Hattori Akira 服部明

… Alternative Names

HATTORI Akira 服部明

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Researcher Number	50300893
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Affiliation (Current)	2025: 京都大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2025: 京都大学, 薬学研究科, 准教授 2012 – 2016: 京都大学, 薬学研究科(研究院), 准教授 2015: 京都大学, 大学院薬学研究科, 准教授 2014 – 2015: 京都大学, 薬学研究院, 准教授 2007 – 2012: Kyoto University, 薬学研究科, 准教授 … More 2008: 独立行政法人理化学研究所, 辻本細胞生化学研究室, 客員研究員 2005 – 2006: RIKEN, Lab.of Cell.Biochem., Senior Research Scientist, 辻本細胞生化学研究室, 先任研究員 2004: 独立行政法人理化学研究所, 辻本細胞生化学研究室, 研究員 2003: 独立行政法人理化学研究所, 細胞生化学研究室, 研究員 2002: 理化学研究所, 細胞生科学研究室, 研究員 1999 – 2001: 理化学研究所, 細胞生化学研究室, 研究員 1998: 理化学研究所, 細胞生化学研究室, 基礎科学特別研究員 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Biological pharmacy / Tumor biology / General physiology / Chemical biology / Biological Sciences / Functional biochemistry Except Principal Investigator Obstetrics and gynecology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields … More / Pathological medical chemistry / Biological pharmacy / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Chemical pharmacy / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Surgery related to the biological and sensory functions and related fields / Biological pharmacy Less
Keywords	Principal Investigator 脱ユビキチン化酵素 / 小胞体アミノペプチダーゼ / X線結晶構造解析 / 脂肪細胞由来ロイシンアミノペプチダーゼ / アミノペプチダーゼ / ユビキチン / 小胞体貯留機構 / MHCクラスI抗原ペプチド / オキシトシナーゼサブファミリー / 胎盤性ロイシンアミノペプチダーゼ … More / プローブ / activity-based probe / プロテアーゼ / 部位特異的変異導入法 / 脂肪細胞由来ロイシンアミノペプチターゼ / 白血球由来アルギニンアミノペプチダーゼ / 阻害剤 / ユビキチン添加酵素 / p120カテニン / USP47 / 細胞間接着 / ユビキチン化修飾 / anisomycin / p38MAPキナーゼ / HIF-1 / 低酸素応答 / タンパク質分解 / プロテアソーム / 低酸素誘導因子 / 脱ユビキチン化酵素活性 / システインプロテアーゼ / activety-based probe / プロテオミクス解析 / アクティビティーベースドプローブ / ユビキチン様ドメイン / 酸化ストレス / 活性制御 / 小胞体貯留 / マクロファージ / HLA / 一塩基多型 / 強直性脊椎炎 / 抗原ペプチド / 遺伝子発現調節 / Laeverin / 基質特異性 / 抗原提示 / M1ファミリー / 白血球由来アルギニンアミノペプチターゼ / 小胞体アミノペプチターゼ / 活性発現メカニズム / インターフェロンーγ / 遺伝子発現調節機構 / タンパク質結晶化 / ウィルス感染 / インターフェロン-γ / 内在性抗原生成 / 小胞体 / 酵母Two-Hybrid法 / 小胞体内腔可溶性タンパク質 / 血圧調節 / CHO細胞 / 金属酵素 / ペプチドホルモン / プロモーター領域 / 遺伝子構造 / オキシトシナーゼ / シグナル伝達 / セラミド / COX-2 / MAPキナーゼファミリー / 細胞質ホスホリパーゼA2 / L929細胞 / インテグリン / Caspase / cPLA2 / 細胞内シグナル伝達系 / アポトーシス / 腫瘍壊死因子 … More Except Principal Investigator laeverin / 胚シグナル / 分子ひずみ / 免疫寛容 / 胎盤性ロイシンアミノペプチダーゼ / 脂肪細胞由来ロイシンアミノペプチダーゼ / アミノペプチダーゼ / 小員環 / シクロブテン / 中員環 / 小胞体アミノペプチダーゼ / オキシトシナーゼサブファミリー / 白血球由来アルギニンアミノペプチダーゼ / 幹細胞 / 生物活性分子 / 面性不斉 / 臍帯血 / 胎児循環幹細胞 / バソプレシン / Laeverin / HCG / ERAP1 / ノックアウトマウス / 不斉合成 / 反応開発 / シクロブタン / 有機合成 / 一酸化窒素 / 高血圧症 / 免疫細胞 / 着床 / 透明帯 / 胚着床 / 胎盤形成 / 大量発現系 / アミノペプチダーゼA / 分子不斉 / 多環芳香族炭化水素 / フロー合成 / 微小環境形成 / がん幹細胞 / 刺激応答型分子 / 生理活性物質 / 炭素四員環 / イノラート / 多環芳香族化合物 / 酸化 / C-C結合開裂 / ひずみ化合物 / 刺激応答 / ADC / 精密有機合成 / ひずみ分子 / 癌転移 / 自己免疫疾患 / 免疫応答異常 / 電子環状反応 / 新規反応 / ヘリセン / シクロブタノン / シクロプロパン / 生理活性天然物 / キラリティ / 有機材料 / 医薬候補化合物 / 小員環化合物 / 中員環化合物 / ヒト絨毛 / テロメラーゼ活性 / Oct4 / hTERT / 初期絨毛 / 遺伝子改変マウス / 絨毛間質 / 循環幹細胞 / 絨毛由来幹細胞 / 透明帯の糖鎖構造 / 着床不全 / 高架式十字迷路試験 / 強制水泳試験 / 尾懸垂試験 / ERAP1-/-マウス / 遺伝子欠損マウス / セロトニン / ER Retention Mechanism / MHC Class I Antigenic Peptides / NRK52E Cells / Leukocyte-derived Arginine Aminopeptidase / Adipocyte-derived Leucine Aminopeptidase / Placental Leucine Aminopeptidase / Oxytocinase Subfamily / Aminopeptidase / 小胞体貯留機構 / 腎尿細管 / 本態性高血圧症 / 小胞体貯留 / 抗原ペプチド / 小胞体内貯留 / MHCクラスI抗原ペプチド / 腎尿細管細胞 / 白血球由来アルギニンアミノペブチダーゼ / cDNA CLONING / BLOOD PRESSURE / VASOPRESSIN / BIOACTIVE PEPTIDE / ADIPOCYTE-DERIVED LEUCINE AMINBOPEPTIDASE / PLACENTAL LEUCINE AMINOPEPTIDASE / OXYTOCINASE / AMINOPEPTIDASE / 胎盤性ロイシンアミノペプチターゼ / 金属酵素 / タンパク質結晶化 / CHO細胞 / ペプチドホルモン / 神経細胞 / プロモーター領域 / 尿細管 / 遺伝子クローニング / 血圧調節 / 生理活性ペプチド / オキシトシナーゼ / カルモジュリン / MyD88 / Toll-様受容体 / アルギニン / M1アミノペプチダーゼ / 触媒反応 / 合成化学 / 四員環炭化水素 / 生物活性天然物 / 機能性分子 / 天然物合成 / ヒト絨毛外栄養膜細胞 / NO産生 / LPS / インターフェロン / マクロファージ / 樹状細胞 / 胚認識 / 糖鎖抗原 / EPF / 絨毛外栄養膜細胞 / 子宮内膜 / 血小板 / 末梢血単核球 / 妊娠 / 黄体形成 / 組織再構築 / アンギオテンシンIV / 立体構造解析 / 白血球由来アルギニンアミノペップチダーゼ / リーベリン / 一塩基多型 / 基質特異性 / 阻害剤 / インターフェロン-γ / HuVEC / 血管新生 Less

がん悪性化の共通制御点を形成するユビキチン修飾反応の解明とその創薬への応用Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kyoto University
分子ひずみを活用する生体機能分子の創出
- Principal Investigator
  
  高須清誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kyoto University
脈管内がん幹細胞の胚シグナル分子による微小環境形成機構とそれを標的にした治療戦略
- Principal Investigator
  
  藤原浩
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
ユビキチン修飾反応による細胞間接着維持の分子メカニズムの解明と創薬への応用Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kyoto University
新規胚シグナルlaeverinの幹細胞と免疫システムに対する作用の解明と臨床応用
- Principal Investigator
  
  藤原浩
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
Identification and analysis of a new group of diseases with a common etiology of abnormal immune response to embryonic signals
- Principal Investigator
  
  Fujiwara Hiroshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
Design, Synthesis and Evaluation of Biologically Active Molecules Based on Ring Strain
- Principal Investigator
  
  Takasu Kiyosei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Kyoto University
Promoting mechnisms of embryonic signals in embryo implantation induced by the immune system
- Principal Investigator
  
  Hiroshi Fujiwara
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
Identification and analysis of circulating embryonic stem cells derived from human chorionic stroma at early stage
- Principal Investigator
  
  Fujiwara Hiroshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
Analysis of chorionic villi-derived embryo stem cells by novel sten cell markers, laeberin and hTERT
- Principal Investigator
  
  Hiroshi Fujiwara
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
Identification of non-canonical degradation pathway of HIF-1 alpha promoted by de-ubiqutinating enzyme inhibitor.Principal Investigator
- Principal Investigator
  
  Hattori Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto University
Stereocontrolled synthesis of poly-substituted medium-sized cyclic compounds by electrocyclic ring opening reaction and the synthesis of biologically active molecules
- Principal Investigator
  
  Takasu Kiyosei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Role of ERAP1 in the pathogenesis of mental disorders
- Principal Investigator
  
  TSUJIMOTO MASAFUMI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Teikyo Heisei University
Identification of embryo-derived implantation-inducing factors (embryonic signals) and their clinical application
- Principal Investigator
  
  Hiroshi Fujiwara
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
Discovery of new reactions and utilities of 4-membered carbocyles based on their unique ring strains.
- Principal Investigator
  
  TAKASU KIYOSEI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Pathophysiological roles of M1 aminopeptidases
- Principal Investigator
  
  TSUJIMOTO Masafumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Teikyo Heisei University
Mechanism of unanchored polyubiquitin chain productionPrincipal Investigator
- Principal Investigator
  
  HATTORI Akira
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Kyoto University
Role of aminopeptidases in atherosclerosis
- Principal Investigator
  
  TSUJIMOTO Masafumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Teikyo Heisei University
Induction of immune-tolerance by a novel human trophoblast-specific soluble factor, laeverin
- Principal Investigator
  
  FUJIWARA Hiroshi
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyoto University
抗原トリミングアミノペプチダーゼの作用発現メカニズムと制御Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Biochemical and physiological studies on deubiquitinating enzymes based on an analysis of the enzymatic activity dynamicsPrincipal Investigator
- Principal Investigator
  
  HATTORI Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical biology
- Research Institution
  Kyoto University
Analysis of maternal recognition through embryo-specific sugar antigen and its inducing mechanisms for embryo implantation and placentation
- Principal Investigator
  
  FUJIWARA Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
  Kyoto University
免疫系による発生初期胚の認識機構-透明帯を利用した哺乳類の着床誘導戦略の証明-
- Principal Investigator
  
  藤原浩
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyoto University
Analysis of tissue remodeling mechanisms by circulating blood cells during human reproduction
- Principal Investigator
  
  FUJIWARA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyoto University
Biological Function of the M1 Family of Human AminopeptidasesPrincipal Investigator
- Principal Investigator
  
  HATTORI Akira
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Mechanisms of Enzymatic Action of the Oxytocinase Subfamily of Aminopeptidases
- Principal Investigator
  
  TSUJIMOTO Masafumi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
小胞体におけるMHCクラスI提示抗原のN末端トリミング過程の分子メカニズム解析Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
  The Institute of Physical and Chemical Research
血管新生の制御を目指した新たな標的分子の探索
- Principal Investigator
  
  TSUJIMOTO Masafumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
抗原ペプチドプロセシングにおける小胞体アミノペプチダーゼの作用メカニズムの解明Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
The oxytocinase subfamily of M1 aminopeptidases
- Principal Investigator
  
  TSUJIMOTO Masafumi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  RIKEN
オキシトシナーゼサブファミリーの細胞内膜系局在の意義およびそのメカニズムの解明Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
オキシトシナーゼサブファミリーに属する新規酵素の生理機能の解明Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
STRUCTURE AND FUNCTION OF NOVEL AMINOPEPTIDASES BELONGING TO OXYTOCINASE SUB-FAMILY
- Principal Investigator
  
  TSUJIMOTO Masafumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Riken
腫瘍壊死因子によるアポトーシス誘導のシグナル系におけるcPLA_2の役割の解明Principal Investigator
- Principal Investigator
  
  服部明
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research

[Book] Aminopeptidase Q/Laeverin in Handbook of Proteolytic Enzymes 3rd ed2013
- Author(s)
  Hattori A, Maruyama M, Fujiwara H, & Tsujimoto M
- Data Source
  KAKENHI-PROJECT-23310160
[Book] Handbook of Proteolytic Enzymes (Aminopeptidase Q/Laeverin)2013
- Author(s)
  Akira Hattori
- Total Pages
  3
- Publisher
  Elsevier
- Data Source
  KAKENHI-PUBLICLY-23133504
[Book] in Handbook of Proteolytic Enzymes 3^<rd> ed2013
- Author(s)
  Hattori A, Maruyama M, Fujiwara H, & Tsujimoto M
- Publisher
  Aminopeptidase Q/Laeverin
- Data Source
  KAKENHI-PROJECT-24659099
[Book] Aminopeptidase Q/Laeverin in Handbook of proteolytic enzymes third edition2013
- Author(s)
  Akira Hattori, Masato Maruyama Hiroshi Fujiwara Masafumi Tsujimoto
- Total Pages
  4104
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-24659153
[Book] Handbook of Proteolytic Enzymes, 3rd Edition2011
- Author(s)
  Hattori A., et al.
- Publisher
  Elsevier(in press)
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Establishment of an MR1 Presentation Reporter Screening System and Identification of Phenylpropanoid Derivatives as MR1 Ligands2023
- Author(s)
  Matsuoka Takuro、Hattori Akira、Oishi Shinya、Araki Mitsugu、Ma Biao、Fujii Toshiki、Arichi Norihito、Okuno Yasushi、Kakeya Hideaki、Yamasaki Sho、Ohno Hiroaki、Inuki Shinsuke
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 66 Issue: 17 Pages: 12520-12535
- DOI
  10.1021/acs.jmedchem.3c01122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17975, KAKENHI-PROJECT-22K06677, KAKENHI-PROJECT-22KJ1866, KAKENHI-PLANNED-22H05183, KAKENHI-PLANNED-23H04882, KAKENHI-PROJECT-23H00403, KAKENHI-PROJECT-23K27294
[Journal Article] Bisabosqual A: a novel asparagine synthetase inhibitor suppressing the proliferation and migration of human non-small cell lung cancer A549 cells.2023
- Author(s)
  Pan Y-J., Suzuki T, Sakai S., Hirano Y., Ikeda H., Hattori A., Dohmae N., Nishio K. and Kakeya H.
- Journal Title
  
  Eur. J. Pharm.
  
  Volume: 960 Pages: 176156-176156
- DOI
  10.1016/j.ejphar.2023.176156
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06677, KAKENHI-PLANNED-23H04882
[Journal Article] Laeverin/aminopeptidase Q induces indoleamine 2,3-dioxygenase-1 in human monocytes2023
- Author(s)
  Suzuki Takuma、Iizuka Takashi、Kagami Kyosuke、Matsumoto Takeo、Yamazaki Rena、Daikoku Takiko、Horie Akihito、Ono Masanori、Hattori Akira、Fujiwara Hiroshi
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 9 Pages: 107692-107692
- DOI
  10.1016/j.isci.2023.107692
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16765, KAKENHI-PROJECT-22K06677
[Journal Article] Spheroid formation induces chemokine production in trophoblast-derived Swan71 cells.2023
- Author(s)
  Kanda T., Kagami K., Iizuka T., Kasama H., Matsumoto T., Sakai Y., Suzuki T., Yamamoto M., Matsuoka A., Yamazaki R., Hattori A., Horie A., Daikoku T., Ono M. and Fujiwara H.
- Journal Title
  
  American J. Reprod. Immunol.
  
  Volume: 90 Issue: 2
- DOI
  10.1111/aji.13752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06677
[Journal Article] Acute-phase protein-like properties of endoplasmic reticulum aminopeptidase 1.2019
- Author(s)
  Goto Y, Nakamura TJ, Ogawa K, Hattori A, Tsujimoto M.
- Journal Title
  
  J Biochem.
  
  Volume: 165 Issue: 2 Pages: 159-165
- DOI
  10.1093/jb/mvy090
- NAID
  40021809947
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07114, KAKENHI-PROJECT-16K08630
[Journal Article] Factors Regulating Human Extravillous Trophoblast Invasion: Chemokine-peptidase and CD9-integrin Systems2018
- Author(s)
  Fujiwara Hiroshi、Matsumoto Hisanori、Sato Yukiyasu、Horie Akihito、Ono Masanori、Nakamura Mitsuhiro、Mizumoto Yasunari、Kagami Kyosuke、Fujiwara Tomoko、Hattori Akira、Maida Yoshiko、Daikoku Takiko、Imakawa Kazuhiko、Araki Yoshihiko
- Journal Title
  
  Current Pharmaceutical Biotechnology
  
  Volume: 19 Issue: 10 Pages: 764-770
- DOI
  10.2174/1389201019666181029164906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11111, KAKENHI-PROJECT-16K07114, KAKENHI-PROJECT-16K11107
[Journal Article] CD9 suppresses human extravillous trophoblast invasion2016
- Author(s)
  Matsumoto H, Sato Y, Horie A, Suginami K, Tani H, Hattori A, Araki Y, Kagami K, Konishi I, Fujiwara H
- Journal Title
  
  Placenta
  
  Volume: 47 Pages: 105-112
- DOI
  10.1016/j.placenta.2016.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293358, KAKENHI-PROJECT-16K15702, KAKENHI-PROJECT-16K07114, KAKENHI-PROJECT-16K11085
[Journal Article] Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages2015
- Author(s)
  Yoshikuni Goto, Kenji Ogawa, Takahiro J Nakamura, Akira Hattori, Masafumi Tsujimoto
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 157 Issue: 6 Pages: 439-49
- DOI
  10.1093/jb/mvv001
- NAID
  40020489236
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659153, KAKENHI-PROJECT-26860160, KAKENHI-PROJECT-25293083
[Journal Article] Involvement of Phenylalanine 297 in the Construction of the Substrate Pocket of Human Aminopeptidase B.2015
- Author(s)
  Ohnishi A., Watanabe J., Ogawa Y., Goto Y., Hattori A., Tsujimoto M.
- Journal Title
  
  Biochemistry
  
  Volume: 54(39) Issue: 39 Pages: 6062-70
- DOI
  10.1021/acs.biochem.5b00964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460172, KAKENHI-PROJECT-25293083
[Journal Article] Substrate-dependentnitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages2015
- Author(s)
  Goto, Y., Ogawa, K., Nakamura, T.J., Hattori, A. and Tsujimoto, M.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 157 Pages: 439-449
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15088
[Journal Article] Role of glutamine-169 in the substrate recognition of human aminopeptidase B.2014
- Author(s)
  Ogawa Y, Ohnishi A, Goto Y, Sakuma Y, Watanabe J, Hattori A, Tsujimoto M.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1840 Pages: 1872-1881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160
[Journal Article] Role of glutamine-169 in the substrate recognition of human aminopeptidase B2014
- Author(s)
  Ogawa Y, Ohnishi A, Goto Y, Sakuma Y, Watanabe J, Hattori A, Tsujimoto M
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1840 Issue: 6 Pages: 1872-1881
- DOI
  10.1016/j.bbagen.2014.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-24790083, KAKENHI-PROJECT-25293083, KAKENHI-PROJECT-25460172
[Journal Article] TLR-Mediated Secretion of Endoplasmic Reticulum Aminopeptidase 1 from Macrophages2014
- Author(s)
  Goto Y, Ogawa K, Nakamura TJ, Hattori A, Tsujimoto M.
- Journal Title
  
  J Immunol
  
  Volume: 192 Issue: 9 Pages: 4443-4452
- DOI
  10.4049/jimmunol.1300935
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-24659153, KAKENHI-PROJECT-24790083, KAKENHI-PROJECT-24790238, KAKENHI-PROJECT-25293083, KAKENHI-PROJECT-26860160
[Journal Article] Chemical tagging of a drug target using 5-sulfonyl tetrazole2013
- Author(s)
  Otsuki S, Nishimura S, Takabatake H, Nakajima K, Takasu Y, Yagura T, Sakai Y, Hattori A, & Kakeya H
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 23 Issue: 6 Pages: 1608-1611
- DOI
  10.1016/j.bmcl.2013.01.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-221S0001
[Journal Article] Endoplasmic reticulum aminopeptidases : biochemistry, physiology and pathology2013
- Author(s)
  Hattori A, & Tsujimoto M
- Journal Title
  
  J Biochem
  
  Volume: 154 Issue: 3 Pages: 219-228
- DOI
  10.1093/jb/mvt066
- NAID
  40019769818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-24659153, KAKENHI-PROJECT-25293083
[Journal Article] New insights into the role of aminopeptidases in the treatment for both preeclampsia and preterm labor2013
- Author(s)
  Mizutani S, Tsunemi T, Mizutani E, Hattori A, Tsujimoto M, & Kobayashi H
- Journal Title
  
  Expert Opin Investig Drugs
  
  Volume: 22 Issue: 11 Pages: 1425-1436
- DOI
  10.1517/13543784.2013.825248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099
[Journal Article] Design of pH-dependent DNA Cleavage Agents Activated through Ring Contraction Rearrangement2013
- Author(s)
  Yuuki Nagamoto, Akira Hattori, Hideaki Kakeya, Yoshiji Takemoto, Kiyosei Takasu
- Journal Title
  
  Chem. Commun.
  
  Volume: (In Press) Issue: 26 Pages: 262-264
- DOI
  10.1039/c3cc39246e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02579, KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659003, KAKENHI-PROJECT-24659099, KAKENHI-PUBLICLY-24106719
[Journal Article] Association of epigenetic alterations in the human C7orf24 gene with the aberrant gene expression in malignant cells2013
- Author(s)
  Ohno Y, Hattori A, Yoshiki T, & Kakeya H
- Journal Title
  
  J Biochem
  
  Volume: 154 Issue: 4 Pages: 355-362
- DOI
  10.1093/jb/mvt063
- NAID
  40019817550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099
[Journal Article] Exon 10 coding sequence is important for endoplasmic reticulum retention of endoplasmic reticulum minopeptidase 12012
- Author(s)
  Akira Hattori, Yoshikuni Goto Masafumi Tsujimoto
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 35 Pages: 601-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659153
[Journal Article] Laeverin/amino peptidase Q induces trophoblast invasion during human early placentation2012
- Author(s)
  Horie A, Fujiwara H, Sato Y, Suginami K, Matsumoto H, Maruyama M, Konishi I, Hattori A.
- Journal Title
  
  Hum Reprod
  
  Volume: 27 Issue: 5 Pages: 1267-76
- DOI
  10.1093/humrep/des068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390452, KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24592470, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-24659730, KAKENHI-PUBLICLY-23133504
[Journal Article] Tumescenamide C, an antimicrobial cyclic lipodepsipeptide from Streptomyces sp2012
- Author(s)
  Kishimoto S, Tsunematsu Y, Nishimura S, Hayashi Y, Hattori A, & Kakeya H
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Issue: 27-28 Pages: 5572-5578
- DOI
  10.1016/j.tet.2012.04.075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099
[Journal Article] C7orf24/gamma-glutamyl cyclotransferase as a molecular target for cancer chemotherapy2012
- Author(s)
  Ohno Y, Hattori A, & Kakeya H
- Journal Title
  
  Nihon Rinsho
  
  Volume: 70 Pages: 723-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160
[Journal Article] Laeverin/aminopeptidase Q induces trophoblast invasion during human early placentation2012
- Author(s)
  Horie A, Fujiwara H, Sato Y, Suginami K, Matsumoto H, Maruyama M, Konishi I, Hattori A
- Journal Title
  
  Hum Reprod
  
  Volume: 27 Pages: 1267-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390389
[Journal Article] Exon 10 Coding Sequence Is Important for Endoplasmic Reticulum Retention of Endoplasmic Reticulum Aminopeptidase 12012
- Author(s)
  Hattori A, Goto Y & Tsujimoto M
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 4 Pages: 601-605
- DOI
  10.1248/bpb.35.601
- NAID
  130001872211
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-24790083, KAKENHI-PUBLICLY-23133504
[Journal Article] C7orf24/gamma-glutamyl cyclotransferase as a molecular target for cancer chemotherapy2012
- Author(s)
  Ohno Y, Hattori A, & Kakeya H
- Journal Title
  
  Nihon Rinsho
  
  Volume: 70 Pages: 723-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659099
[Journal Article] Involvement of Glutamine-238 in the Substrate Specificity of Human Laeverin/Aminopeptidase Q2011
- Author(s)
  Hattori A., Goto Y., et al
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 1 Pages: 24-27
- DOI
  10.1248/bpb.34.24
- NAID
  130000402257
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23133504, KAKENHI-PROJECT-23310160
[Journal Article] The Arabidopsis aminopeptidase LAP2 regulates plant growth, leaf longevity and stress response2011
- Author(s)
  Hattori A., Waditee-Sirisattha R., et al
- Journal Title
  
  New Phytol
  
  Volume: 191 Issue: 4 Pages: 958-969
- DOI
  10.1111/j.1469-8137.2011.03758.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23133504
[Journal Article] Multiple NF-Y-binding CCAAT boxes are essential for transcriptional regulation of the human C7orf24 gene, a novel tumor-associated gene2011
- Author(s)
  Ohno Y, Hattori A, Ueda M, Kageyama S, Yoshiki T, & Kakeya H
- Journal Title
  
  FEBS J
  
  Volume: 278 Issue: 21 Pages: 4088-4099
- DOI
  10.1111/j.1742-4658.2011.08314.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160
[Journal Article] Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides.2011
- Author(s)
  Zervoudi E, Papakyriakou A, Georgiadou D, Evnouchidou I, Gajda A, Poreba M, Salvesen GS, Drag M, Hattori A, Swevers L, Vourloumis D, Stratikos E.
- Journal Title
  
  Biochem J 435
  
  Pages: 411-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Involvement of glutamine-238 in the substrate specificity of human laeverin/aminopeptidase Q.2011
- Author(s)
  Goto Y, Yoshioka R, Arisaka N, Hattori A, Tsujimoto M.
- Journal Title
  
  Biol Pharm Bull 34
  
  Pages: 24-27
- NAID
  130000402257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gamma2011
- Author(s)
  Hattori A., Goto Y., et al
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 24 Pages: 21906-21914
- DOI
  10.1074/jbc.m111.239111
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23133504, KAKENHI-PROJECT-23310160
[Journal Article] Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides2011
- Author(s)
  Hattori A., Zervoudi E., et al
- Journal Title
  
  Biochem J
  
  Volume: 435 Issue: 2 Pages: 411-420
- DOI
  10.1042/bj20102049
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23133504
[Journal Article] Role of the Arabidopsis leucine aminopeptidase 22011
- Author(s)
  Hattori A., Waditee-Sirisattha R., et al
- Journal Title
  
  Plant Signal Behav
  
  Volume: 6 Pages: 1581-1583
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23133504
[Journal Article] The arabidopsis aminopeptidase LAP2 regulates plant growth2011
- Author(s)
  Waditee R, Shibato J, Rakwal R, Sirisattha S, Hattori A, Nakano T, Takabe T, Tsujimoto M.
- Journal Title
  
  leaf longevity and stress response. New Phytologist in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme2011
- Author(s)
  Hattori A., Evnouchidou I., et al
- Journal Title
  
  J Immunol
  
  Volume: 186 Issue: 4 Pages: 1909-13
- DOI
  10.4049/jimmunol.1003337
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23133504
[Journal Article] Oxytocin hypersensitivity in pregnant P-LAP deficient mice.2009
- Author(s)
  Ishii M, Naruse K, Hattori A, Tsujimoto M, Ishiura S, Numaguchi Y, Murohara T, Kobayashi H, Mizutani S.
- Journal Title
  
  Life Sci 84
  
  Pages: 668-672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs).2009
- Author(s)
  Ishii M, Hattori A, Numaguchi Y, Ma X, Nagasaka T, Tsujimoto M, Murohara T, Kobayashi H, Mizutani S.
- Journal Title
  
  Early Hum Dev 85
  
  Pages: 589-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Histidine 379 of Human Laeverin/Aminopeptidase Q, a Nonconserved Residue within the Exopeptidase Motif, Defines Its Distinctive Enzymatic Properties.2009
- Author(s)
  Maruyama M, Arisaka N, Goto Y, Ohsawa Y, Inoue H, Fujiwara H, Hattori A, Tsujimoto M,
- Journal Title
  
  Journal of Biological Chemistry 284
  
  Pages: 34692-34702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390434
[Journal Article] Histidine 379 of human laeverin/aminopeptidase Q, a nonconserved residue within the exopeptidase motif, defines its distinctive enzymatic properties.2009
- Author(s)
  Maruyama M, Arisaka N, Goto Y, Ohsawa Y, Inoue H, Fujiwara H, Hattori A, Tsujimoto M.
- Journal Title
  
  J Biol Chem 284
  
  Pages: 34692-34702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Glutamine-181 is crucial in the enzymatic activity and substrate specificity of human endoplasmic-reticulum aminopeptidase-1.2008
- Author(s)
  Goto Y, Tanji H, Hattori A, Tsujimoto M.
- Journal Title
  
  Biochem J 416
  
  Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] The effect of recombinant aminopeptidase a on hypertension in spontaneously hypertensive rats: its effect in comparison with candesartan.2008
- Author(s)
  Ishii M, Hattori A, Numaguchi Y, Tsujimoto M, Ishiura S, Kobayashi H, Murohara T, Wright JW, Mizutani S.
- Journal Title
  
  Horm Metab Res 40
  
  Pages: 887-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Glutamine-181 is crucial in the enzymatic activity and substrate specificity of human endoplasmic reticulum aminopeptidase-12008
- Author(s)
  Goto, Y., Tanji, H., Hattori, A. and Tsujimoto, M.
- Journal Title
  
  Biochem. J. 416
  
  Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] New insights into the importance of aminopeptidase A in hypertension.2008
- Author(s)
  Mizutani S, Ishii M, Hattori A, Nomura S, Numaguchi Y, Tsujimoto M, Kobayshi H, Murohara T, Wright JW.
- Journal Title
  
  Heart Fail Rev 13
  
  Pages: 273-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] The effect of recombinant aminopeptidase A on hypertension in spontaneously hypertensive rats: its effect in comparison with candesartan2008
- Author(s)
  Ishii, M., Hattori, A., Numaguchi, Y., Tsujimoto, M., Ishiura, S., Kobayashi, H., Murohara, T., Wright, J.W. and Mizutani, S.
- Journal Title
  
  Horm Metab Res. 40
  
  Pages: 887-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] Biochemical and enzymatic properties of the M1 family of aminopeptidases involved in the regulation of blood pressure.2008
- Author(s)
  Tsujimoto M, Goto Y, Maruyama M, Hattori A.
- Journal Title
  
  Heart Fail Rev 13
  
  Pages: 285-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590057
[Journal Article] Biochemical and enzymatic properties of M1 family of aminopeptidases involved in the regulation of blood pressure2008
- Author(s)
  Tsujimoto, M., Goto, Y., Maruyama, M. and Hattori, A.
- Journal Title
  
  Heart Fail. Rev. 13
  
  Pages: 285-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] Laeverin/aminopeptidase Q, a novel bestatin sensitive leucine aminopeptidase belonging to the M1 family of aminopsptidases2007
- Author(s)
  Maruyama, M., Hattori, A., Goto, Y., Ueda, M., Maeda, M., Fujiwara, H. and Tsujimoto, M.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 20088-20096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] Asparatic acid-221 is critical in the calcium-induced modulation of the enzymatic activity of human aminopeptidase A2007
- Author(s)
  Goto, Y., Hattori, A., Mizutani, S, and Tsujimoto, M.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 37074-37081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] Essential role of placental leucine aminopeptidase in gynecologic malignancy2007
- Author(s)
  Mizutani, S., Shibata, K., Kikkawa, F., Hattori, A., Tsujimoto, M., Ishii, M. and Kobayashi, H.
- Journal Title
  
  Expert Opin. Ther. Targets 11
  
  Pages: 453-461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] New insights into the importance of aminopeptidase A in hypertension2007
- Author(s)
  Mizutani, S., Ishii, M., Hattori, A., Nomura, S., Numaguchi, Y., Tsujimoto, M., Kobayashi, H., Murohara, T. and Wright, J.S.
- Journal Title
  
  Heart Fail. Rev. 13
  
  Pages: 273-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] M1アミノペプチダーゼファミリーノ新たな生理機能2006
- Author(s)
  服部明
- Journal Title
  
  日本血栓止血学会誌 17
  
  Pages: 20-28
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] M1アミノペプチダーゼファミリーの新たな生理機能2006
- Author(s)
  服部明, 辻本雅文
- Journal Title
  
  日本血栓止血学会誌 17
  
  Pages: 20-28
- NAID
  10021258236
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] M1アミノペプチダーゼファミリーの新たな生理機能2006
- Author(s)
  服部明
- Journal Title
  
  日本血栓止血学会誌 17
  
  Pages: 20-28
- NAID
  10021258236
- Data Source
  KAKENHI-PROJECT-18790077
[Journal Article] M1アミノペプチダーゼファミリーの新たな生理機能2006
- Author(s)
  服部明, 辻本雅文
- Journal Title
  
  日本血栓止血学会誌 17
  
  Pages: 20-28
- NAID
  10021258236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-12006
- Author(s)
  Goto, Y., Hattori, A., Ishii, Y. and Tsujimoto, M.
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 1833-1838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] Physiological roles of M1 aminopeptidase family2006
- Author(s)
  Hattori A., Tsujimoto M.
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis 17
  
  Pages: 20-28
- NAID
  10021258236
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] Enzymatic properties of human aminopeptidase A; regulation of its enzymatic activity by calcium and angiotensin IV2006
- Author(s)
  Goto, Y., Hattori, A., Ishii, Y., Mizutani, S. and Tsujimoto, M.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 23503-23513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390031
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2005
- Author(s)
  Tsujimoto M., Hattori A.
- Journal Title
  
  Biochiemica et Biophysica Acta (in press)
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2005
- Author(s)
  Tsujimoto M., Hattori A.
- Journal Title
  
  Biochiemica et Biophysica Acta (in press)
- Data Source
  KAKENHI-PROJECT-16790072
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2005
- Author(s)
  Tsujimoto M., Hattori A.
- Journal Title
  
  Biochim.Biophys.Acta 1751
  
  Pages: 9-18
- Data Source
  KAKENHI-PROJECT-16790072
[Journal Article] Endoplasmic reticulum aminopeptidases2005
- Author(s)
  Hattori A., Tsujimoto M.
- Journal Title
  
  Kagaku To Seibutsu 43
  
  Pages: 739-745
- NAID
  130003634488
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] 小胞体アミノペプチダーゼの発見とそのMHCクラスI抗原ペプチドプロセシングにおける役割2005
- Author(s)
  服部明, 辻本雅文
- Journal Title
  
  化学と生物 43巻11号
  
  Pages: 698-704
- Data Source
  KAKENHI-PROJECT-16659025
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2005
- Author(s)
  Tsujimoto M., Hattori A.
- Journal Title
  
  Biochimica et Biophysica Acta 1751
  
  Pages: 9-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2005
- Author(s)
  Tsujimoto M., Hattori A.
- Journal Title
  
  Biochim.Biophys.Acta 1751
  
  Pages: 9-18
- Data Source
  KAKENHI-PROJECT-16659025
[Journal Article] 小胞体アミノペプチダーゼの発見とそのMHCクラスI抗原ペプチドプロセシングにおける役割2005
- Author(s)
  服部明, 辻本雅文
- Journal Title
  
  化学と生物 43巻11号
  
  Pages: 698-704
- Data Source
  KAKENHI-PROJECT-16790072
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2005
- Author(s)
  Tsujimoto M., Hattori A.
- Journal Title
  
  Biochim.Biophys.Acta 1751
  
  Pages: 9-18
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] 小胞体アミノペプチダーゼの発見とMHCクラス-I抗原ペプチドプロセシングにおける役割2005
- Author(s)
  服部明, 辻本雅文
- Journal Title
  
  化学と生物 43
  
  Pages: 739-745
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2005
- Author(s)
  Tsujimoto M., Hattori A.
- Journal Title
  
  Biochiemica et Biophysica Acta (in press)
- Data Source
  KAKENHI-PROJECT-16659025
[Journal Article] 小胞体アミノペプチダーゼの発見とそのMHCクラスI抗原ペプチドプロセシングにおける役割2005
- Author(s)
  服部明, 辻本雅文
- Journal Title
  
  化学と生物 43巻11号
  
  Pages: 698-704
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] Processing of antigenic peptidases by aminopeptidases2004
- Author(s)
  Hattori A., Tsujimoto M.
- Journal Title
  
  Biological and Pharmaceutical.Bulletin 27
  
  Pages: 777-780
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] Processing of antigenic peptidases by aminopeptidases2004
- Author(s)
  Hattori A., Tsujimoto M.
- Journal Title
  
  Biological and Pharmaceutical Bulletin 27
  
  Pages: 777-780
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] Processing of antigenic peptidases by aminopeptidases2004
- Author(s)
  Hattori A., Tsujimoto M.
- Journal Title
  
  Biological and Pharmaceutical.Bulletin 27
  
  Pages: 777-780
- Data Source
  KAKENHI-PROJECT-16790072
[Journal Article] Processing of antigenic peptidases by aminopeptidases2004
- Author(s)
  Hattori A., Tsujimoto M.
- Journal Title
  
  Biological and Pharmaceutical Bulletin 27
  
  Pages: 777-780
- Data Source
  KAKENHI-PROJECT-16659025
[Journal Article] The oxytocinase subfamily of M1 aminopeptidases2003
- Author(s)
  Hattori A., Tsujimoto M
- Journal Title
  
  SEIKAGAKU 70
  
  Pages: 1225-1230
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Journal Article] オキシトシナーゼサブファミリー-M1アミノペプチダーゼの新しいサブファミリーの同定とその生理機能2003
- Author(s)
  服部明, 辻本雅文
- Journal Title
  
  生化学 75
  
  Pages: 1225-1230
- NAID
  50000316590
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390032
[Presentation] Calpain7の細胞内局在の解析2018
- Author(s)
  松原拓真、服部　明、掛谷秀昭
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07114
[Presentation] 酵素反応速度論的解析を用いた脱ユビキチン化酵素USP47の C末端領域の機能解析2018
- Author(s)
  福岡啓太、服部　明、掛谷秀昭
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07114
[Presentation] 小胞体アミノペプチダーゼはエンドトキシンショック時に惹起される一酸化窒素合成を亢進する2016
- Author(s)
  後藤芳邦, 小川健司, 中村孝博, 服部明, 辻本雅文
- Organizer
  第89回　日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K15088
[Presentation] 細菌感染に伴い血中に分泌されたERAP1は血中アミノ酸や一酸化窒素濃度を調節する2015
- Author(s)
  後藤芳邦, 小川健司, 中村孝博, 青嶋瑞樹, 荒俣晃貴, 高田慧, 町田綾乃, 吉野僚太, 服部明, 辻本雅文
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25293083
[Presentation] 細菌感染に伴い血中に分泌されたERAP1は血中アミノ酸や一酸化窒素濃度を調節する2015
- Author(s)
  後藤芳邦, 小川健司, 中村孝博, 青嶋瑞樹, 荒俣晃貴, 高田慧, 町田綾乃, 吉野僚太, 服部明, 辻本雅文
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15088
[Presentation] Activity-based Profiling による酸化ストレス感受性脱ユビキチン化酵素の同定2014
- Author(s)
  服部明, 西川未来子, 朴錦花, 小林万祐子, 森吉英子, 掛谷秀昭
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学(京都府)
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 脱ユビキチン化酵素(USP)47の分子内ドメインの機能解析2014
- Author(s)
  青木　豊, 朴　錦花, 小林　万祐子, 服部　明, 掛谷　秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学（熊本県）
- Invited
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱Urm1化活性の検出および分子同定2014
- Author(s)
  小林万祐子, 服部明, 青木豊, 掛谷秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学（熊本県）
- Invited
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱Urm1化活性の検出および分子同定2014
- Author(s)
  小林万祐子, 服部明, 青木豊, 掛谷秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学(熊本県)
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 脱Urm1化活性の検出および分子同定2014
- Author(s)
  小林万祐子, 服部明, 青木豊, 掛谷秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学（熊本県）
- Invited
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 脱Urm1化活性の検出および分子同定2014
- Author(s)
  小林万祐子,服部明,青木豊,掛谷秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学(熊本県)
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱ユビキチン化酵素(USP)47の分子内ドメインの機能解析2014
- Author(s)
  青木豊,朴錦花,小林万祐子,服部明,掛谷秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学(熊本県)
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱ユビキチン化酵素(USP)47の分子内ドメインの機能解析2014
- Author(s)
  青木　豊, 朴　錦花, 小林　万祐子, 服部　明, 掛谷　秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学（熊本県）
- Invited
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 脱ユビキチン化酵素(USP)47 の分子内ドメインの機能解析2014
- Author(s)
  青木豊, 朴錦花, 小林万祐子, 服部明, 掛谷秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本大学(熊本県)
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 分泌型小胞体アミノペプチダーゼ１によるArg産生を介したマクロファージのNO産生亢進2013
- Author(s)
  後藤芳邦、小川健司、中村孝博、服部　明、辻本雅文
- Organizer
  第18回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25293083
[Presentation] 脱ユビキチン化酵素(USP)47 の活性発現機構の解析2013
- Author(s)
  朴錦花, 服部明, 青木豊, 小林万祐子, 森吉英子, 掛谷秀昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] マクロファージ古典的活性化に重要なトール様受容体を介した小胞体アミノペプチダーゼの分泌2013
- Author(s)
  後藤芳邦、小川健司、中村孝博、服部　明、辻本雅文
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25293083
[Presentation] マクロファージ古典的活性化に重要なトール様受容体を介した小胞体アミノペプチダーゼの分泌2013
- Author(s)
  後藤芳邦、小川健司、中村孝博、服部　明、辻本雅文
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659153
[Presentation] 分泌型小胞体アミノペプチダーゼ１によるArg産生を介したマクロファージのNO産生亢進2013
- Author(s)
  後藤芳邦、小川健司、中村孝博、服部　明、辻本雅文
- Organizer
  第18回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-24659153
[Presentation] 脱ユビキチン化酵素(USP)47の活性発現機構の解析2013
- Author(s)
  朴錦花,服部明,青木豊,小林万祐子,森吉英子,掛谷秀昭
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] Activity-based Profillingによる酸化ストレス感受性脱ユビキチン化酵素の同定2012
- Author(s)
  服部　明
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学（京都府）
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 脱ユビキチン化酵素UCH-L3 は酸化ストレスの標的タンパク質である2012
- Author(s)
  服部明, 西川未来子, 朴錦花, 小林万祐子, 森吉英子, 掛谷秀昭
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] Enzymatic properties of recombinant human ubiquitin specific protease 472012
- Author(s)
  朴錦花, 田代亜衣香, 西川未来子, 森吉英子, 服部明, 掛谷秀昭
- Organizer
  Organization for Oncology and Translational Research (OOTR) 8th Annual Meeting
- Place of Presentation
  ウェスティン都ホテル(京都府)
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 小胞体アミノペプチダーゼの分泌を介したマクロファージのNO産生亢進2012
- Author(s)
  後藤芳邦, 小川健司, 服部明, 辻本雅文
- Organizer
  第85回　日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24659153
[Presentation] 脱ユビキチン化酵素UCH-L3は酸化ストレスの標的タンパク質である2012
- Author(s)
  服部　明
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱ユビキチン化酵素(USP)47 の活性発現における分子内ユビキチン様ドメインの役割2012
- Author(s)
  朴錦花, 服部明, 青木豊, 小林万祐子, 森吉英子, 掛谷秀昭
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] Activity-based Profillingによる酸化ストレス感受性脱ユビキチン化酵素の同定2012
- Author(s)
  服部　明
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学（京都府）
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱ユビキチン化酵素UCH-L3は酸化ストレス下で不活性化される2012
- Author(s)
  服部明、西川未来子, 他
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] ヒトUSP47の脱ユビキチン化酵素活性の解析2012
- Author(s)
  服部明、朴錦花, 他
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] Activity-based Profilingによる酸化ストレス感受性脱ユビキチン化酵素の同定2012
- Author(s)
  服部明,西川未来子,朴錦花,小林万祐子,森吉英子,掛谷秀昭
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都大学(京都府)
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱ユビキチン化酵素(USP)47の活性発現における分子内ユビキチン様ドメインの役割2012
- Author(s)
  朴錦花,服部明,青木豊,小林万祐子,森吉英子,掛谷秀昭
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] ヒトUSP47 の脱ユビキチン化酵素活性の解析2012
- Author(s)
  朴錦花, 田代亜衣香, 西川未来子, 森吉英子, 服部明, 掛谷秀昭
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 脱ユビキチン化酵素UCH-L3は酸化ストレスの標的タンパク質である2012
- Author(s)
  服部　明
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] 脱ユビキチン化酵素UCH-L3は酸化ストレスの標的タンパク質である2012
- Author(s)
  服部明,西川未来子,朴錦花,小林万祐子,森吉英子,掛谷秀昭
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] Enzymatic properties of recombinant human ubiquitin specific protease 472012
- Author(s)
  朴錦花,田代亜衣香,西川未来子,森吉英子,服部明,掛谷秀昭
- Organizer
  Organization for Oncology and Translational Research (OOTR) 8th Annual Meeting
- Place of Presentation
  ウェスティン都ホテル(京都府)
- Data Source
  KAKENHI-PROJECT-24659099
[Presentation] 脱ユビキチン化酵素UCH-L3 は酸化ストレス下で不活性化される2012
- Author(s)
  西川未来子, 小林万祐子, 朴錦花, 森吉英子, 服部明, 掛谷秀昭.
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] グランザイムB をレポーターに用いた脱ユビキチン化酵素活性測定法の構築2011
- Author(s)
  服部明, 朴錦花, 田代亜衣香, 森吉英子, 掛谷秀昭
- Organizer
  第84回日本生化学会大
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] ヒト絨毛外栄養膜細胞に特異的な新規aminopeptidase "laeverin"の同定とその機能解析2011
- Author(s)
  服部明、堀江昭史, 他
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンタービル(大阪府)
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PUBLICLY-23133504
[Presentation] 小胞体アミノペプチダーゼの分泌機構2011
- Author(s)
  服部明、後藤芳邦, 他
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-23133504
[Presentation] Characterization of enzymatic properties of recombinant human specific protease 472011
- Author(s)
  Hattori, A., Tashiro, A., Piao, J.-H., Moriyoshi, E., Kakeya, H.
- Organizer
  7th General Meeting of the International Proteolysis Society
- Place of Presentation
  San Diego, USA
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] ヒトC7orf24の遺伝子発現は、転写開始点近傍の3ヶ所のCCAAT配列に制御される2011
- Author(s)
  服部明、大野裕司, 他
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] ヒトC7orf24 の遺伝子発現は,転写開始点近傍の3 ヶ所のCCAAT 配列に制御される2011
- Author(s)
  大野裕司, 服部明, 上田正道, 影山進,吉貴達寛, 掛谷秀昭
- Organizer
  第84回日本生化学会大
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] グランザイムBをレポーターに用いた脱ユビキチン化酵素活性測定法の構築2011
- Author(s)
  服部明, 他
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23310160
[Presentation] Phagocytosis of macrophages is facilitated by secreted ER-aminopeptidase 1.2010
- Author(s)
  後藤芳邦、小川健司、服部明、辻本雅文
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同年会
- Place of Presentation
  兵庫・神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] Histidine-379 of human laeverin/aminopeptidase Q, a non-conserved residue within the exopeptidase motif, defines its distinctive enzymatic properties2009
- Author(s)
  Hattori A, Maruyama M, Arisaka Y, Goto Y, Ohsawa Y, Inoue H, Fujiwara H, Tsujimoto M
- Organizer
  6th General meeting of the International Proteolytic Society
- Place of Presentation
  Gold Coast, Australia.
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] 小胞体アミノペプチダーゼの基質認識機構2009
- Author(s)
  後藤芳邦、丹治弘江、服部明、辻本雅文
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] Histidine-379 of human Laeverin/aminopeptidase Q, a non-conserved residue within the exopeptidase motif, defines its distincitive enzymatic properites2009
- Author(s)
  Hattori A, et al.
- Organizer
  6th General Meeting of the International Proteolysis Society
- Place of Presentation
  Gold Coast, Australia
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] マクロファージにおけるカルシウムを介した小胞体アミノペプチダーゼ-1の分泌2009
- Author(s)
  後藤芳邦、服部明、辻本雅文
- Organizer
  第82回日本生化学会
- Place of Presentation
  兵庫・神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] 小胞体アミノペプチダーゼの基質認識機構2009
- Author(s)
  後藤芳邦、服部明、辻本雅文
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都・京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] ERAP-1/A-LAP is secreted from macrophages treated with IFN- and LPS2009
- Author(s)
  Goto Y, Hattori A, Tsujimoto M
- Organizer
  6th General meeting of the International Proteolytic Society.
- Place of Presentation
  Gold Coast, Australia
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] カルシウムイオンによるアミノペプチダーゼ-A活性制御機構の解明2008
- Author(s)
  後藤芳邦、服部明、辻本雅文
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] ヒト脂肪細胞由来ロイシンアミノペプチダーゼのGln-181残基は基質特異性に重要である2008
- Author(s)
  後藤芳邦、丹治弘江、服部明、辻本雅文
- Organizer
  第13回病態と治療のおけるプロテアーゼとインヒビター学会
- Place of Presentation
  大阪・千里
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] ヒト脂肪細胞由来ロイシンアミノペプチダーゼのGln-181残基は基質特異性に重要である2008
- Author(s)
  後藤芳邦、丹治弘江、服部明、辻本雅文
- Organizer
  第31回日本分子生物学会年会/第81回日本生化学会大会 (BMB2008)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] 点変異導入によるヒトLaeverinのHis379残基の機能解析2008
- Author(s)
  有坂尚美、丸山正人、服部明、辻本雅文
- Organizer
  第31回日本分子生物学会・第82回日本生化学会合同年会
- Place of Presentation
  兵庫・神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] ヒトLaeverinの酵素学的性状の発現におけるHis379残基の役割2008
- Author(s)
  有坂尚美、丸山正人、服部明、辻本雅文
- Organizer
  第13回病態と治療のおけるプロテアーゼとインヒビター学会
- Place of Presentation
  大阪・千里
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] ヒト脂肪細胞由来ロイシンアミノペプチダーゼのGln-181残基は基質特異性に重要である2008
- Author(s)
  後藤芳邦、丹治弘江、服部明、辻本雅文
- Organizer
  第31回日本分子生物学会・第81回日本生化学会合同年会
- Place of Presentation
  兵庫・神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20590057
[Presentation] 点変異導入によるヒトlaeverinのHis379残基の機能解明2008
- Author(s)
  有坂尚美、丸山正人、服部明、辻本雅文
- Organizer
  第31回日本分子生物学会年会/第81回日本生化学会大会 (BMB2008)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] Asp-221 plays an essential role in the calcium-dependent regulatory mechanism of human aminopeptidase A2007
- Author(s)
  Goto, Y., Hattori, A. Mizutani, S. and Tsujimoto, M.
- Organizer
  5th General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras, Greece
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] Laeverin/aminopeptidase Q: a novel bestatin sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases2007
- Author(s)
  Maruyama, M., Hattori, A, Goto, Y. Ueda, M. Maeda, M. Fujiwara, H. and Tsujimoto, M.
- Organizer
  5th General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras, Greece
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] ヒトアミノペプチダーゼAのAsp221残基はカルシウムによる活性制御に必須である2007
- Author(s)
  後藤芳邦、服部明、辻本雅文
- Organizer
  第30回日本分子生物学会年会/第80回日本生化学会大会 (BMB2007)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] 新規M1アミノペプチダーゼLaeverinの生理機能2007
- Author(s)
  服部明
- Organizer
  第30回日本分子生物学会年会/第80回日本生化学会大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-18790077
[Presentation] 新規アミノペプチダーゼLaeverinの酵素学的性状の解析2007
- Author(s)
  丸山正人、服部明、後藤芳邦、藤原浩、辻本雅文
- Organizer
  第12回病態と治療におけるプロテアーゼとインヒビター研究会
- Place of Presentation
  吹田
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] アミノペプチダーゼAのAsp-221残基はカルシウムとの相互作用に必須である2007
- Author(s)
  後藤芳邦、服部明、辻本雅文
- Organizer
  第12回病態と治療におけるプロテアーゼとインヒビター研究会
- Place of Presentation
  吹田
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] 新規MlアミノペプチダーゼLaeverinの生理機能2007
- Author(s)
  服部明
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] Characterization of recombinant human aminopeptidase A expressed in a baculovirus system2006
- Author(s)
  Goto, Y., Hattori, M., Ishii, Y., Mizutani, S. and Tsujimoto, M.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] Identification of SDF2-L1 as a binding protein to A-LAP/ERAP1 in the ER2006
- Author(s)
  Hattori, A. and Tsujimoto, M.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] 神経細胞における胎盤性ロイシンアミノペプチダーゼの細胞膜移行誘導メカニズムの解明2006
- Author(s)
  丸山正人、服部明、辻本雅文
- Organizer
  第11回病態と治療におけるプロテアーゼとインヒビター研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] アミノペプチダーゼAの酵素活性はCa^<2+>とAngIVによって制御される2006
- Author(s)
  後藤芳邦、服部明、辻本雅文
- Organizer
  第50回日本薬学会関東支部大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-18390031
[Presentation] 小胞体アミノペプチダーゼ1遺伝子欠損に伴うマクロファージのFcγ受容体依存性貪食活性の低下
- Author(s)
  後藤芳邦、小川健司、中村孝博、服部明、辻本雅文
- Organizer
  第87回　日本生化学会大会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25293083
[Presentation] 小胞体アミノペプチダーゼ1遺伝子欠損に伴うマクロファージのFcγ受容体依存性貪食活性の低下
- Author(s)
  後藤芳邦、小川健司、中村孝博、服部明、辻本雅文
- Organizer
  第８７回日本生化学会大会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24659153

1. FUJIWARA Hiroshi (30252456)

# of Collaborated Projects: 12 results

# of Collaborated Products: 4 results
2. ARAKI Yoshihiko (70250933)

# of Collaborated Projects: 9 results

# of Collaborated Products: 2 results
3. TSUJIMOTO Masafumi (00281668)

# of Collaborated Projects: 7 results

# of Collaborated Products: 54 results
4. 河崎洋志 (50303904)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. 大黒多希子 (30767249)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. TAKASU KIYOSEI (10302168)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. 小野政徳 (70348712)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
8. GOTO Yoshikuni (90455345)

# of Collaborated Projects: 4 results

# of Collaborated Products: 30 results
9. NISHI Eiichiro (30362528)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
10. NISHIO Takeshi (70303790)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. SATO Yukiyasu (00508236)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
12. YAMAOKA Yousuke (60624723)

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# of Collaborated Products: 0 results
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# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
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# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. MARUYAMA Masato (00399445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
17. FUJITA Jun (50173430)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. OISHI Shinya (80381739)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. NISHIMURA Shinichi (30415260)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
20. HORIE Akihito (30535836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 高倉正博 (20313661)

# of Collaborated Projects: 2 results

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22. 毎田佳子 (20397219)

# of Collaborated Projects: 2 results

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23. 篁俊成 (00324111)

# of Collaborated Projects: 2 results

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24. 藤原智子 (60310744)

# of Collaborated Projects: 2 results

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25. 鏡京介 (80748616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
26. 前田大地 (30585500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
27. 水本泰成 (00420331)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
28. TAKAO Yumi (20447957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. INOUE Hideshi (20184765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. IMAGAWA Kazuhiko (00291956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. OGAWA Yuko (30267330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
32. OGAWA Kenji (50251418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
33. NOMURA Yosihiro (10228372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. MATSUMOTO Hideo (00312257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. MASUDA Shinako (30342851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. TANIOKA Toshihiro (80360585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 京哲 (50272969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 中村充宏 (50377397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 岩垂純平 (00740739)

# of Collaborated Projects: 1 results

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40. 和田泰三 (30313646)

# of Collaborated Projects: 1 results

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41. 谷内江昭宏 (40210281)

# of Collaborated Projects: 1 results

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42. 堀家慎一 (40448311)

# of Collaborated Projects: 1 results

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43. 渡会浩志 (70415339)

# of Collaborated Projects: 1 results

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44. 伊藤潤哉 (30454143)

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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47. 八木真太郎 (60447969)

# of Collaborated Projects: 1 results

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48. 松下貴史 (60432126)

# of Collaborated Projects: 1 results

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49. 後藤典子 (10251448)

# of Collaborated Projects: 1 results

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50. 黒田悠介 (60870863)

# of Collaborated Projects: 1 results

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51. Shimoda Kazuma

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. Ito Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. Ogawa Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. Tsutsumi Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. 小西郁生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 山崎晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 井貫晋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hattori Akira 服部 明

HATTORI Akira 服部 明

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がん悪性化の共通制御点を形成するユビキチン修飾反応の解明とその創薬への応用Principal Investigator

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ユビキチン修飾反応による細胞間接着維持の分子メカニズムの解明と創薬への応用Principal Investigator

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Identification of non-canonical degradation pathway of HIF-1 alpha promoted by de-ubiqutinating enzyme inhibitor.Principal Investigator

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Hattori Akira 服部明

HATTORI Akira 服部明