TATSUNO Ichiro 立野一郎

Researcher Number	50311642
Other IDs
Affiliation (Current)	2023: 名古屋市立大学, 医薬学総合研究院(医学), 講師
Affiliation (based on the past Project Information) *help	2019 – 2022: 名古屋市立大学, 医薬学総合研究院(医学), 講師 2016 – 2018: 名古屋市立大学, 大学院医学研究科, 講師 2012 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 講師 2014: 名古屋市立大学, 大学院医学研究科, 講師 2007 – 2012: Nagoya City University, 大学院・医学研究科, 講師 2008: Nagoya City University, 大学院医学研究科, 講師 1999 – 2002: 東京大学, 医科学研究所, 助手
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / Infectious disease medicine Except Principal Investigator Basic Section 54030:Infectious disease medicine-related / Basic Section 49050:Bacteriology-related / Plastic surgery / Bacteriology (including mycology) / Infectious disease medicine / Bacteriology (including Mycology)
Keywords	Principal Investigator NADase / LEE / O157 / Adherence / A群レンサ球菌 / IFS / Nga / 付着 / fab / msrD … More / salK / salR / mefA / Sreptococcus / S. pyogenes / 劇症型感染症 / pyogenes / streptococcus / 二成分制御系 / Ａ群レンサ球菌 / fabT / ゲノム / 病原性 / transcriptional regulator / O157:H7 / 転写制御 / 蛍光 / LPS / 連鎖球菌 / レンサ球菌 / 人喰いバクテリア / A 群レンサ球菌 / A 群連鎖球菌 / 劇症型 / A群連鎖球菌 / Tir / intimin / 腸管出血性大腸菌 / 腸上皮細胞 / TypeIII / EHEC … More Except Principal Investigator A群連鎖球菌 / 病原性 / A群レンサ球菌 / 二成分制御系 / 立体構造 / センサータンパク質 / バイオフィルム / 二成分制御因子 / 劇症型感染症 / 転写調節因子 / DNA分解酵素 / 蛋白質分解酵素 / 発現制御 / 毒素蛋白質 / 糖鎖結合タンパク質 / 貪食能 / マクロファージ / 二成分制御 / 組換えタンパク質 / ヒスチジンキナーゼ / 血管吻合 / 細菌 / 緑膿菌 / 微小血管 / 感染 / 吻合部血栓 / 微小血栓 / 機序 / 抗凝固剤 / 血栓 / 黄色ブドウ球菌 / 細菌感染 / 微小血管吻合 / 病原因子 / 薬剤耐性 / msr(D) / mef(A) / ファージ / マクロライド / 環境因子 / 人食いバクテリア / 転写因子 / 遺伝子発現 / 遺伝子制御 / 環境ストレス / 二成分制御系因子 Less

Group A Streptococcus glycoproteins evade immune defense mechanisms
- Principal Investigator
  
  井坂雅徳
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nagoya City University
機能未同定転写調節因子の網羅的解析によるA群レンサ球菌毒素蛋白質発現機構の解明
- Principal Investigator
  
  長谷川忠男
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Nagoya City University
A群連鎖球菌spy1588遺伝子の酸感受性機構と病原性発症機構の解明
- Principal Investigator
  
  井坂雅徳
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nagoya City University
Elucidation of macrolide resistance mechanism and virulence of Streptococcus pyogenes focused on phage DNA
- Principal Investigator
  
  Hasegawa Tadao
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Nagoya City University
Microvascular anastomotic thrombosis by bacterial infection: Elucidation of mechanism and counterplan
- Principal Investigator
  
  Toriyama Kazuhiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nagoya City University
Mechanism of a streptococcal toxic shock syndrome to non-streptococcal toxic shock syndrome transition in the novel-type Streptococcus pyogenes isolatesPrincipal Investigator
- Principal Investigator
  
  Tatsuno Ichiro
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagoya City University
Search for genes involved in severe invasion of Streptococcus pyogenes and analysis of the mechanism of its onset
- Principal Investigator
  
  Isaka Masanori
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagoya City University
Analysis of the networks of the two-component sensor proteins in Streptococcus pyogenes
- Principal Investigator
  
  HASEGAWA Tadao
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nagoya City University
In vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolatesPrincipal Investigator
- Principal Investigator
  
  TATSUNO Ichiro
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nagoya City University
Characterization of the NAD-glycohydrolase in streptococcal strainsPrincipal Investigator
- Principal Investigator
  
  TATSUNO Ichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nagoya City University
Analysis of novel adherence factors for initial infection in Enterohemorrhagic Escherichia coli O157SakaiPrincipal Investigator
- Principal Investigator
  
  TATSUNO Ichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
腸管出血性大腸菌O157Sakaiによる腸管上皮細胞への付着機構の解析Principal Investigator
- Principal Investigator
  
  立野一郎
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo

[Journal Article] A greater effect on clarithromycin resistance of mef associated msr than mef associated msr in Streptococcus pyogenes2022
- Author(s)
  Tatsuno Ichiro、Isaka Masanori、Hasegawa Tadao
- Journal Title
  
  Microbiology and Immunology
  
  Volume: - Issue: 6 Pages: 299-306
- DOI
  10.1111/1348-0421.12974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08443
[Journal Article] Mechanism of transient photothermal inactivation of bacteria using a wavelength-tunable nanosecond pulsed lase2021
- Author(s)
  Ichiro Tatsuno, Yuna Niimi, Makoto Tomita, Hiroshi Terashima, Tadao Hasegawa & Takahiro Matsumoto
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 22310-22310
- DOI
  10.1038/s41598-021-01543-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H01150, KAKENHI-PROJECT-18K08443
[Journal Article] Streptococcus pyogenes TrxSR Two-Component System Regulates Biofilm Production in Acidic Environments2021
- Author(s)
  Isaka Masanori、Okamoto Akira、Miura Yutaka、Tatsuno Ichiro、Maeyama Jun-ichi、Hasegawa Tadao
- Journal Title
  
  Infection and Immunity
  
  Volume: 89 Issue: 11
- DOI
  10.1128/iai.00360-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08443, KAKENHI-PROJECT-21K07035
[Journal Article] Transient photothermal inactivation of Escherichia coli stained with visible dyes by using a nanosecond pulsed laser2020
- Author(s)
  Kohmura Y, Igami N, Tatsuno I, Hasegawa T, Matsumoto T.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 17805-17805
- DOI
  10.1038/s41598-020-74714-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08443
[Journal Article] Complete Genome Sequence of emm1 Streptococcus pyogenes 10-85, a Strain Isolated from a Patient with Streptococcal Toxic Shock Syndrome in Japan.2019
- Author(s)
  Tatsuno I, Isaka M, Matsumoto M, Nishio N, Matsui H, Hasegawa T.
- Journal Title
  
  Microbiol Resour Announc
  
  Volume: 13 Issue: 24
- DOI
  10.1128/mra.00453-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08443, KAKENHI-PROJECT-19K11687, KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-16K01827
[Journal Article] Prevalence of emm1 Streptococcus pyogenes having a novel type of genomic composition.2019
- Author(s)
  Tatsuno I, Isaka M, Matsumoto M, Hasegawa T.
- Journal Title
  
  Microbiol Immunol
  
  Volume: 63 Issue: 10 Pages: 413-426
- DOI
  10.1111/1348-0421.12739
- NAID
  40022036977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08443, KAKENHI-PROJECT-15K09575
[Journal Article] Total Internal Reflection of Deep-Ultraviolet Light in a Water Waveguide and Its Application to Water Disinfection Technologies2019
- Author(s)
  Matsumoto Takahiro、Kikojima Rika、Fukuoka Tomomi、Tatsuno Ichiro、Hasegawa Tadao
- Journal Title
  
  Water
  
  Volume: 11 Issue: 2 Pages: 294-294
- DOI
  10.3390/w11020294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575
[Journal Article] Instantaneous Water Purification by Deep Ultraviolet Light in Water Waveguide: Escherichia Coli Bacteria Disinfection2019
- Author(s)
  Matsumoto Takahiro、Tatsuno Ichiro、Hasegawa Tadao
- Journal Title
  
  Water
  
  Volume: 11 Issue: 5 Pages: 968-968
- DOI
  10.3390/w11050968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575
[Journal Article] Homologous role of CovRS two-component regulatory system in NAD+ -glycohydrolase activity in Streptococcus dysgalactiae subsp. equisimilis as in Streptococcus pyogenes.2019
- Author(s)
  Hasegawa T, Matsumoto M, Hata N, Yano H, Isaka M, Tatsuno I.
- Journal Title
  
  APMIS
  
  Volume: 127 Issue: 2 Pages: 87-92
- DOI
  10.1111/apm.12914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-16K08782, KAKENHI-PROJECT-26461512, KAKENHI-PROJECT-18K08443
[Journal Article] Functional Predominance of msr(D), Which Is More Effective as mef(A)-Associated Than mef(E)-Associated, Over mef(A)/mef(E) in Macrolide Resistance in Streptococcus pyogenes2018
- Author(s)
  Tatsuno Ichiro、Isaka Masanori、Masuno Katsuaki、Hata Nanako、Matsumoto Masakado、Hasegawa Tadao
- Journal Title
  
  Microbial Drug Resistance
  
  Volume: in press Issue: 8 Pages: 1089-1097
- DOI
  10.1089/mdr.2017.0277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-16K08782, KAKENHI-PROJECT-26461512, KAKENHI-PROJECT-18K08443
[Journal Article] Female GADD34 mice develop age-related inflammation and hepatocellular carcinoma2017
- Author(s)
  Nishio Naomi、Hasegawa Tadao、Tatsuno Ichiro、Isaka Masanori、Isobe Ken-ichi
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 17 Issue: 12 Pages: 2593-2601
- DOI
  10.1111/ggi.13080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-16K01827, KAKENHI-PROJECT-26461512, KAKENHI-PROJECT-16H05280
[Journal Article] Characterisation of clinically isolated Streptococcus pyogenes from balanoposthitis patients, with special emphasis on emm89 isolates2017
- Author(s)
  Hasegawa Tadao、Hata Nanako、Matsui Hideyuki、Isaka Masanori、Tatsuno Ichiro
- Journal Title
  
  Journal of Medical Microbiology
  
  Volume: 66 Issue: 4 Pages: 511-516
- DOI
  10.1099/jmm.0.000460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-26461512
[Journal Article] Characterization of clinically isolated Streptococcus pyogenes from balanoposthitis patients with special emphasis on emm89 isolates.2017
- Author(s)
  Hasegawa T, Hata N, Matsui H, Isaka M, Tatsuno I
- Journal Title
  
  J. Med. Microbiol.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08782
[Journal Article] Further evidence on the functional predominance of msr(D) over mef(A) and mef(E) in macrolide resistance in Streptococcus pyogenes2017
- Author(s)
  Ichiro Tatsuno, Masanori Isaka, Katsuaki Masuno, Nanako Hata, Masakado Matsumoto, Tadao Hasegaw.
- Journal Title
  
  Microbiology
  
  Volume: inpress
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461512
[Journal Article] Two-Component Systems Involved in Susceptibility to Nisin A in Streptococcus pyogenes.2016
- Author(s)
  Kawada-Matsuo M, Tatsuno I, Arii K, Zendo T, Oogai Y, Noguchi K, Hasegawa T, Sonomoto K, Komatsuzawa H.
- Journal Title
  
  Appl Environ Microbiol.
  
  Volume: 16；82（19） Issue: 19 Pages: 5930-5939
- DOI
  10.1128/aem.01897-16
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05036, KAKENHI-PROJECT-15K20365, KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-15K11017
[Journal Article] Predominant role of msr(D) over mef(A) in macrolide resistance in Streptococcus pyogenes.2016
- Author(s)
  Zhang Y, Tatsuno I, Okada R, Hata N, Matsumoto M, Isaka M, Isobe K, Hasegawa T.
- Journal Title
  
  microbiology
  
  Volume: 162 Issue: 1 Pages: 46-52
- DOI
  10.1099/mic.0.000206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26461512
[Journal Article] The YvqE two-component system controls biofilm formation and acid production in Streptococcus pyogenes2016
- Author(s)
  Isaka M, Tatsuno I, Maeyama J, Matsui H, Zhang Y, Hasegawa T
- Journal Title
  
  APMIS
  
  Volume: In press Issue: 7 Pages: 574-85
- DOI
  10.1111/apm.12538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460558, KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-26461512
[Journal Article] Pathogenic description of Streptococcus pyogenes among invasive and non-invasive diseases in Aichi, Japan.2016
- Author(s)
  Matsumoto M, Yamada K, Suzuki M, Adachi H, Kobayashi S, Yamashita T, Minagawa H, Tatsuno I, Hasegawa T.
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575
[Journal Article] Relevance of spontaneous fabT mutations to a streptococcal toxic shock syndrome to non-streptococcal toxic shock syndrome transition in the novel-type Streptococcus pyogenes isolates that lost a salRK.2016
- Author(s)
  Tatsuno I, Okada R, Matsumoto M, Hata N, Matsui H, Zhang Y, Isaka M, Hasegawa T.
- Journal Title
  
  APMIS
  
  Volume: 124 Issue: 5 Pages: 414-24
- DOI
  10.1111/apm.12521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-26461512
[Journal Article] Description of the Pathogenic Features of <i>Streptococcus pyogenes</i> Isolates from Invasive and Non-Invasive Diseases in Aichi, Japan2016
- Author(s)
  Masakado Matsumoto, Kazuhiro Yamada, Masahiro Suzuki, Hirokazu Adachi, Shinichi Kobayashi, Teruo Yamashita, Hiroko Minagawa, Ichiro Tatsuno and Tadao Hasegawa
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 69 Issue: 4 Pages: 338-341
- DOI
  10.7883/yoken.JJID.2015.334
- NAID
  130005165475
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08663, KAKENHI-PROJECT-15K09575
[Journal Article] Analysis of the roles of NrdR and DnaB from Streptococcus pyogenes in response to host defense.2015
- Author(s)
  Zhang Y, Okada R, Isaka M, Tatsuno I, Isobe K, Hasegawa T.
- Journal Title
  
  APMIS
  
  Volume: 123 Issue: 3 Pages: 252-259
- DOI
  10.1111/apm.12340
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590531, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26461512
[Journal Article] Simultaneous isolation of emm89-type Streptococcus pyogenes strains with a wild-type or mutated covS gene from a single streptococcal toxic shock syndrome patient2014
- Author(s)
  Masuno K, Okada R, Zhang Y, Isaka M, Tatsuno I, Shibata S, Hasegawa T
- Journal Title
  
  J. Med. Microbiol
  
  Volume: 63 Issue: 4 Pages: 504-507
- DOI
  10.1099/jmm.0.070300-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590531
[Journal Article] Emergence of type I restriction modification system-negative emm1 type Streptococcus pyogenes clinical isolates in Japan.2014
- Author(s)
  Okada R, Matsumoto M, Zhang Y, Isaka M, Tatsuno I, Hasegawa T.
- Journal Title
  
  APMIS
  
  Volume: 122 Pages: 914-921
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461512
[Journal Article] Relevance of the two-component sensor protein CiaH to acid and oxidative stress responses in Streptococcus pyogenes2014
- Author(s)
  Tatsuno I, Isaka M, Okada R, Zhang Y, Hasegawa T
- Journal Title
  
  BMC Res Notes
  
  Volume: 7 Issue: 1 Pages: 189-189
- DOI
  10.1186/1756-0500-7-189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590531, KAKENHI-PROJECT-26461512
[Journal Article] Partial loss of CovS function in Streptococcus pyogenes causes severe invasive disease.2013
- Author(s)
  Tatsuno I, Okada R, Zhang Y, Isaka M, Hasegawa T.
- Journal Title
  
  BMC Res Notes.
  
  Volume: 6(1) Issue: 1 Pages: 126-126
- DOI
  10.1186/1756-0500-6-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425, KAKENHI-PROJECT-24590531
[Journal Article] Characterization of NADase-inactive NAD^+ glycohydrolase in Streptococcus pyogenes.2013
- Author(s)
  Tatsuno I, Isaka M, Hasegawa T.
- Journal Title
  
  Advances in Microbiology.
  
  Volume: 3(1) Issue: 01 Pages: 91-100
- DOI
  10.4236/aim.2013.31015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] Characterization of NADase-inactive NAD+ glycohydrolase in Streptococcus pyogenes.2013
- Author(s)
  Tatsuno I, Isaka M, Hasegawa T.
- Journal Title
  
  Adv Microbiol
  
  Volume: 3 Pages: 91-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590531
[Journal Article] Variation in M protein production among Streptococcus pyogenes strains according to emm genotype.2011
- Author(s)
  Matsumoto M, Suzuki M, Hirose K, Hiramatsu R, Minagawa H, Minami M, Tatsuno I, Okamoto A, Ohta M, Hasegawa T.
- Journal Title
  
  Microbiol Immunol
  
  Volume: 55(6) Issue: 6 Pages: 379-87
- DOI
  10.1111/j.1348-0421.2011.00329.x
- NAID
  10031121482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] Analysis of two-component sensor proteins involved in response to acid stimuli in Streptococcus pyogenes.2011
- Author(s)
  Ichikawa M, Minami M, Isaka M, Tatsuno I, Hasegawa T
- Journal Title
  
  Microbiology
  
  Volume: 157 Issue: 11 Pages: 3187-94
- DOI
  10.1099/mic.0.050534-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590485, KAKENHI-PROJECT-21790425
[Journal Article] Variation in M protein production among Streptococcus pyogenes strains according to emm genotype.2011
- Author(s)
  松本昌門、立野一郎, (7番目)
- Journal Title
  
  Microbiol Immunol
  
  Volume: (In press)
- NAID
  10031121482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] Analysis of two-component sensor proteins involved in the response to acid stimuli in Streptococcus pyogenes2011
- Author(s)
  Ichikawa M, Minami M, Isaka M, Tatsuno I, et al
- Journal Title
  
  Microbiology
  
  Volume: 157 Pages: 3187-3194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] Characterization of virulence-associated and cell-wall-located DNase of Streptococcus pyogenes2010
- Author(s)
  長谷川忠男、立野一郎(4番目)
- Journal Title
  
  Microbiology 156
  
  Pages: 184-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] NADase as a target molecule of in vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates.2010
- Author(s)
  立野一郎, (他3名)
- Journal Title
  
  BMC Microbiol.
  
  Volume: 10 Pages: 144-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] Clindamycin-induced CovS-mediated regulation of the production of virulent exoproteins streptolysin O, NAD glycohydrolase, and streptokinase in Streptococcus pyogenes2010
- Author(s)
  Minami M, Kamimura T, Isaka M, Tatsuno I, Ohta M, Hasegawa T
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 54 Issue: 1 Pages: 98-102
- DOI
  10.1128/aac.00804-09
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590485, KAKENHI-PROJECT-21790425
[Journal Article] Characterization of Streptococcus pyogenes Isolated from Balanoposthitis Patients Presumably Transmitted by Penile-Oral Sexual Intercourse2010
- Author(s)
  南正明、立野一郎(8番目)
- Journal Title
  
  Curr Microbiol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] Detection of invasive protein profile of Streptococcus pyogenes M1 isolates from pharyngitis patients2010
- Author(s)
  Hasegawa T, Okamoto A, Kamimura T, Tatsuno I, Hashikawa S, Yabutani M, Matsumoto M, Yamada K, Isaka M, Minami M, Ohta M
- Journal Title
  
  APMIS
  
  Volume: 118 Issue: 3 Pages: 167-78
- DOI
  10.1111/j.1600-0463.2009.02574.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590485, KAKENHI-PROJECT-21790425
[Journal Article] Characterization of Streptococcus pyogenes isolated from balanoposthitis patients presumably transmitted by penile-oral sexual intercourse2010
- Author(s)
  Minami M, Wakimoto Y, Matsumoto M, Matsui H, Kubota Y, Okada A, Isaka M, Tatsuno I, Tanaka Y, Hasegawa T
- Journal Title
  
  Curr Microbiol
  
  Volume: 61 Issue: 2 Pages: 101-105
- DOI
  10.1007/s00284-010-9581-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590485, KAKENHI-PROJECT-21790425
[Journal Article] Characterization of a virulence-associated and cell-wall-located DNase of Streptococcus pyogenes2010
- Author(s)
  Hasegawa T, Minami M, Okamoto A, Tatsuno I, Isaka M, Ohta M
- Journal Title
  
  Microbiology
  
  Volume: 156 Issue: 1 Pages: 184-190
- DOI
  10.1099/mic.0.031955-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590485, KAKENHI-PROJECT-21790425
[Journal Article] NADase as a target molecule of in vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates2010
- Author(s)
  Tatsuno I, Isaka M, Minami M, Hasegawa T
- Journal Title
  
  BMC Microbiol
  
  Volume: 10 Issue: 1 Pages: 144-144
- DOI
  10.1186/1471-2180-10-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590485, KAKENHI-PROJECT-21790425
[Journal Article] Characterization of Streptococcus pyogenes Isolated from Balanoposthitis Patients Presumably Transmitted by Penile-OralSexual Intercourse2010
- Author(s)
  南正明、立野一郎, (8番目)
- Journal Title
  
  Curr Microbiol.
  
  Volume: 61 Pages: 101-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] Detection of invasive protein profile of Streptococcus pyogenes M1 isolates from pharyngitis patients.2010
- Author(s)
  長谷川忠男、立野一郎(4番目)
- Journal Title
  
  APMIS VOL.118
  
  Pages: 167-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790425
[Journal Article] The streptococcal inhibitor of complement(SIC) protects Streptococcus pyogenes from bacteriocin-like inhibitory substance(BLIS) from Streptococcus salivarius2009
- Author(s)
  Minami M, Ohmori D, Tatsuno I, Isaka M, Kawamura Y, Ohta M, Hasegawa T
- Journal Title
  
  FEMS Microbiol Lett
  
  Volume: 298 Issue: 1 Pages: 67-73
- DOI
  10.1111/j.1574-6968.2009.01696.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590485, KAKENHI-PROJECT-21790425
[Journal Article] Characterization of the NAD-glycohydrolase in streptococcal strains2008
- Author(s)
  立野一郎, 他
- Journal Title
  
  Microbiology 153
  
  Pages: 4253-4260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590452
[Journal Article] Characterization of the NAD-glycohydrolase in streptococcal strains2007
- Author(s)
  Tatsuno I, Sawai J, Okamoto A, Matsumoto M, Minami M, Isaka M, Ohta M, Hasegawa T
- Journal Title
  
  Microbiology 153
  
  Pages: 4253-4260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590452
[Presentation] Prevalence of emm1 Streptococcus pyogenes having a novel type of genomic composition2020
- Author(s)
  立野一郎，井坂雅徳，松本昌門，長谷川忠男
- Organizer
  第９３回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K08443
[Presentation] Prevalence of emm1 Streptococcus pyogenes having a nobel type of genomic composition2020
- Author(s)
  Tatsuno Ichiro, Masanori Isaka, masakado Matsumoto, Tadao Hasegawa
- Organizer
  日本細菌学会
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] A群連鎖球菌二成分制御因子SPY1588の酸感受性と自己リン酸化2019
- Author(s)
  井坂雅徳、立野一郎、前山順一、長谷川忠男
- Organizer
  第９２回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K08443
[Presentation] Prevalence of emm1 Streptococcus pyogenes having a novel type of genomic composition2019
- Author(s)
  立野一郎，井坂雅徳, 松本昌門, 長谷川忠男
- Organizer
  第５６回　日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-18K08443
[Presentation] A 群連鎖球菌二成分制御因子 SPY1588 の酸感受性と自己リン酸化について2019
- Author(s)
  井坂雅徳，立野一郎，前山順一，長谷川忠男
- Organizer
  第９２回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K08443
[Presentation] Two component sensor system SPY1588 regulates biofilm production and promotes transcription of mga gene2018
- Author(s)
  井坂雅徳、立野一郎、前山順一、長谷川忠男
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] 二成分制御センサータンパク質SPY1588は、バイオフィルム産生とmgaプロモーター発現を促進させる2018
- Author(s)
  井坂雅徳、立野一郎、前山順一、長谷川忠男
- Organizer
  第91回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] Functional Predominance of msr(D), Which Is More Effective as mef(A)-Associated Than mef(E)-Associated, Over mef(A)/mef(E) in Macrolide Resistance in Streptococcus pyogenes2018
- Author(s)
  立野一郎、松本昌門、松井秀之、井坂雅徳、長谷川忠男
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] Functional Predominance of msr(D), over mef(E) in Macrolide Resistance in Streptococcus pyogenes2018
- Author(s)
  立野一郎、松本昌門、松井秀之、井坂雅徳、長谷川忠男
- Organizer
  日本細菌学会総会　福岡
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] 二成分制御センサータンパク質 SPY1588 は，バイオフィルム産生と mga プロモーター発現を促進させる2018
- Author(s)
  井坂雅徳，立野一郎，前山順一，長谷川忠男
- Organizer
  第９１回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] Functional predominance of msr(D), over mef(E) in macrolide resistance in Streptococcus pyogenes2018
- Author(s)
  立野一郎、松本昌門、松井秀之、井坂雅徳、長谷川忠男
- Organizer
  第91回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] A群レンサ球菌におけるmef(A), mef(E)マクロライド耐性システムの解析2017
- Author(s)
  長谷川忠男、松本昌門、松井秀之、井坂雅徳、立野一郎
- Organizer
  第54回日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-16K08782
[Presentation] Predominant role of msr(D) over mef(A) in macrolide-resistance in Streptococcus pyogenes2016
- Author(s)
  張顔，立野一郎，松本昌門，井坂雅徳，長谷川忠男
- Organizer
  第89回　日本細菌学会総会
- Place of Presentation
  大阪　国際交流センター(大阪市天王寺区)
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] 化膿レンサ球菌の二成分制御系によるナイシン耐性機構2016
- Author(s)
  松尾美樹、立野一郎、長谷川忠男、小松澤均
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター　(大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] Characterization of spontaneous fabT mutations in the novel-type Streptococcus pyogenes isolates2016
- Author(s)
  立野一郎，松本昌門，松井秀之，井坂雅徳，長谷川忠男
- Organizer
  第89回　日本細菌学会総会
- Place of Presentation
  大阪　国際交流センター(大阪市天王寺区)
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] Characterization of spontaneous fabT mutations in the novel-type Streptococcus pyogenes isolates2016
- Author(s)
  立野一郎、松本昌門、松井秀之、井坂雅徳、長谷川忠男
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター (大阪市)
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] A群レンサ球菌におけるマクロライド系抗生物質耐性メカニズムの解明2016
- Author(s)
  長谷川忠男、立野一郎、井坂雅徳
- Organizer
  第45回東海乳酸菌研究会
- Place of Presentation
  中日パレス（名古屋市）
- Year and Date
  2016-02-06
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] Predominant role of msr (D) over mef (A) in macroride-resistance in Streptococcus pyogenes2016
- Author(s)
  張顔、立野一郎、松本昌門、井坂雅徳、長谷川忠男
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] Streptococcus pyogenes 二成分制御因子はバイオフィルム形成を制御する2015
- Author(s)
  井坂雅徳、立野一郎、岡本陽、前山順一、長谷川忠男
- Organizer
  第29回　日本バイオフィルム学会
- Place of Presentation
  ホテル竹島（愛知県蒲郡市）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] A群レンサ球菌に関する研究2015
- Author(s)
  立野一郎
- Organizer
  第52回日本細菌学会中部支部総会
- Place of Presentation
  名古屋市立大学(名古屋市)
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-15K09575
[Presentation] 二成分制御因子によるA群連鎖球菌のバイオフィルム形成機構の解析2014
- Author(s)
  井坂雅徳、立野一郎、前山順一、長谷川忠男
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京　タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24590531
[Presentation] 近年出現したA群レンサ球菌salR-salK欠損株に関する研究2014
- Author(s)
  立野一郎、岡田涼、張顔、松本昌門、畑七奈子、井坂雅徳、長谷川忠男
- Organizer
  第46回レンサ球菌研究会
- Place of Presentation
  東京大学農学部弥生キャンパス内フードサイエンス棟中島董一郎記念ホール（東京都・文京区）
- Year and Date
  2014-06-27
- Data Source
  KAKENHI-PROJECT-24590531
[Presentation] A群レンサ球菌における二成分制御系センサータンパク質の機能解析2013
- Author(s)
  立野一郎
- Organizer
  東海乳酸菌研究会
- Place of Presentation
  中日パレス（愛知県）
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] A群連鎖球菌二成分制御因子SPY1622のバイオフィルム形成機構の解析2013
- Author(s)
  井坂雅徳、立野一郎、前山順一、長谷川忠男
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ国際会議場（千葉）
- Data Source
  KAKENHI-PROJECT-24590531
[Presentation] S.pyogenes二成分制御系因子SPY1622の酸感受性およびバイオフィルム形成の作用機序2012
- Author(s)
  長谷川忠雄、井坂雅徳、立野一郎, 他3名
- Organizer
  東海乳酸菌研究会
- Place of Presentation
  中日パレス(愛知県)
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] A群レンサ球菌csrS遺伝子の変異と菌の病原性に関する研究2012
- Author(s)
  立野一郎
- Organizer
  日本細菌学会・中部支部総会
- Place of Presentation
  金沢大学医学類十全講堂 (石川県）
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] Analysis of two component regulatory systems in S. pyogenes2012
- Author(s)
  立野一郎
- Organizer
  第85回日本細菌学会
- Place of Presentation
  長崎新聞文化ホール(長崎県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] Analysis of two component regulatory systems in S.pyogenes2012
- Author(s)
  立野一郎, 他4名
- Organizer
  日本細菌学会
- Place of Presentation
  長崎新聞文化ホール(長崎県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] A群レンサ球菌csrS遺伝子の変異と菌の病原性に関する研究2012
- Author(s)
  立野一郎
- Organizer
  日本細菌学会・中部支部総会
- Place of Presentation
  金沢大学医学類十全講堂(石川県)
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] A群レンサ球菌における二成分制御系因子の解析2011
- Author(s)
  立野一郎
- Organizer
  日本細菌学会・中部支部総会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] 劇症型A群連鎖球菌NAD-glycohydrolaseとMタンパク質のマウスへの経鼻投与による抗原性及び防御効果2010
- Author(s)
  井坂雅徳、立野一郎, (他4名)
- Organizer
  日本細菌学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21790425
[Presentation] 劇症型感染症由来A群連鎖球菌によって菌体外に分泌されるNgaタンパク質と病態の関係2009
- Author(s)
  立野一郎、井坂雅徳、南正明、長谷川忠男
- Organizer
  日本細菌学会
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-19590452
[Presentation] A群連鎖球菌Ngaタンパク質のNAD活性に関与する領域及び、劇症型感染症との因果関係についての解析2008
- Author(s)
  立野一郎、井坂雅徳、南正明、松井秀之、長谷川忠男
- Organizer
  日本細菌学会
- Place of Presentation
  京都
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19590452
[Presentation] 劇症型A群連鎖球菌臨床分離株の食菌抵抗性の検討2008
- Author(s)
  井坂雅徳、前山順一、立野一郎、南正明、松井秀之、長谷川忠男
- Organizer
  日本細菌学会
- Place of Presentation
  京都
- Year and Date
  2008-03-24
- Data Source
  KAKENHI-PROJECT-19590452
[Presentation] マウスモデルを用いたA群連鎖球菌劇症型感染症の発症抑制2008
- Author(s)
  立野一郎、井坂雅徳、南正明、長谷川忠男
- Organizer
  日本細菌学会中部支部総会
- Place of Presentation
  金沢
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590452
[Presentation] 劇症型A群連鎖球菌の菌体外毒素Ngaタンパク質及び、Ngaを中和するIFSタンパク質に関する研究2008
- Author(s)
  長谷川忠男、立野一郎
- Organizer
  東海乳酸菌研究会
- Place of Presentation
  名古屋
- Year and Date
  2008-02-02
- Data Source
  KAKENHI-PROJECT-19590452
[Presentation] 近年出現した新規A群レンサ球菌の特性に関する研究
- Author(s)
  岡田涼、松本昌門、張顔、松井秀之、井坂雅徳、立野一郎、長谷川忠男
- Organizer
  第50回日本細菌学会中部支部総会
- Place of Presentation
  蒲郡　ホテル竹島
- Data Source
  KAKENHI-PROJECT-24590531
[Presentation] Molecule identification and property of biofilm formation produced by Streptococcus pyogenes
- Author(s)
  M isaka ,I Tatsuno, J Maeyama,T Hasegawa
- Organizer
  日本細菌学会総会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] Relevance of MefA on macrolide resistance in novel emm1 S pyogenes
- Author(s)
  Y Zhang, M Matsumoto,M Isaka,I Tatsuno,T Hasegawa
- Organizer
  日本細菌学会総会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26461512
[Presentation] S.pyogenes 二成分制御因子SPY1622の酸感受およびバイオフィルム形成の作用機序について
- Author(s)
  井坂雅徳、立野一郎、市川真理子、松井秀之、南正明、長谷川忠男
- Organizer
  第21回Lancefieldレンサ球菌研究会
- Place of Presentation
  大阪大学（大阪）
- Data Source
  KAKENHI-PROJECT-24590531
[Presentation] A群連鎖球菌が産生するバイオフィルムの構成成分の同定とその特性について
- Author(s)
  井坂雅徳、立野一郎、前山順一、長谷川忠男
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  長良川国際会議場（岐阜県・岐阜市）
- Year and Date
  2015-03-26 – 2015-03-27
- Data Source
  KAKENHI-PROJECT-24590531

1. HASEGAWA Tadao (10314014)

# of Collaborated Projects: 7 results

# of Collaborated Products: 60 results
2. ISAKA Masanori (40336673)

# of Collaborated Projects: 7 results

# of Collaborated Products: 49 results
3. 前山順一 (40199641)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. 矢木宏和 (70565423)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Toriyama Kazuhiro (40314017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 内堀貴文 (30625760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐藤秀吉 (70528968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 青山峰芳 (70363918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MINAMI Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
10. 野口和行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 冨田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TATSUNO Ichiro 立野 一郎

Research Projects

Research Products

Co-Researchers

Group A Streptococcus glycoproteins evade immune defense mechanisms

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機能未同定転写調節因子の網羅的解析によるA群レンサ球菌毒素蛋白質発現機構の解明

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A群連鎖球菌spy1588遺伝子の酸感受性機構と病原性発症機構の解明

Principal Investigator

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Elucidation of macrolide resistance mechanism and virulence of Streptococcus pyogenes focused on phage DNA

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Microvascular anastomotic thrombosis by bacterial infection: Elucidation of mechanism and counterplan

Principal Investigator

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Mechanism of a streptococcal toxic shock syndrome to non-streptococcal toxic shock syndrome transition in the novel-type Streptococcus pyogenes isolatesPrincipal Investigator

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Search for genes involved in severe invasion of Streptococcus pyogenes and analysis of the mechanism of its onset

Principal Investigator

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Analysis of the networks of the two-component sensor proteins in Streptococcus pyogenes

Principal Investigator

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In vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolatesPrincipal Investigator

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Characterization of the NAD-glycohydrolase in streptococcal strainsPrincipal Investigator

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Analysis of novel adherence factors for initial infection in Enterohemorrhagic Escherichia coli O157SakaiPrincipal Investigator

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腸管出血性大腸菌O157Sakaiによる腸管上皮細胞への付着機構の解析Principal Investigator

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[Journal Article] A greater effect on clarithromycin resistance of mef associated msr than mef associated msr in Streptococcus pyogenes2022

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TATSUNO Ichiro 立野一郎