HASHIMOTO Nobuyuki 橋本伸之

Researcher Number	50324752
Affiliation (based on the past Project Information) *help	2013: 地方独立行政法人大阪府立病院機構, 大阪府立成人病センター(研究所)リハビリテーション科, 部長 2012: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, その他 2012: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, リハビリテーション科部長 2011: 大阪大学, 医学(系)研究科(研究院), 助教 2007 – 2011: 大阪大学, 医学系研究科, 助教 2008: 大阪大学, 大学院・医学系研究科, 助教 2001 – 2003: 大阪大学, 医学系研究科, 助手
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery
Keywords	Principal Investigator 骨軟部腫瘍 / 肺転移 / 肉腫 / 微小環境 / 直鎖状ユビキチン修飾 / NF-kB / ユビキチン修飾 / NF-κB / 骨肉腫 / メカニズム / 悪性骨軟部腫瘍 … More Except Principal Investigator … More NF-kB / パルテノライド / VCP / 肺転移 / 骨肉腫 / アポトーシス / 微小環境 / 悪性骨腫瘍 / organ-specific metastasis / cadherin / insuline-like growth factor / MAP kinase / tyrosine kinase / osteosarcoma / bone metastasis / 血管新生因子 / 低分子G蛋白 / 増殖因子 / 破骨細胞 / 転移性骨腫瘍 / 遺伝子発現 / 臓器特異性 / 転移性肺腫瘍 / 臓器選択的転移 / カドヘリン / インスリン様増殖因子 / MAPキナーゼ / チロシンキナーゼ / 骨肉種 / 骨転移 / iPS細胞 / 無血清培地 / 骨芽細胞分化 / 化学療法 / 間葉系幹細胞 / 骨再生医療 / VEGF / IκBα / NFκB / HIF-1 / 遊走能 / 抗腫瘍作用 / アピジェニン / 吸入療法 / 細胞増殖 / デコイオリゴヌクレオチド / E2F / NFкB / 骨形成因子 / 転移 Less

Optimization of Regeneration Technique for Large Bone Defect
- Principal Investigator
  
  MYOUI Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
骨肉腫治療標的分子の探索～ラット発癌モデルとマウス肺転移モデルによる解析～Principal Investigator
- Principal Investigator
  
  橋本伸之
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
  Osaka University
Pre-metastatic Niche and Its Role in Lung Metastasis of Malignant Musculoskeletal TumorsPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Nobuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Molecular mechanisms of the metastasis of malignant bone tumors and anti-metastasis therapy
- Principal Investigator
  
  MYOUI Akira
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Metastasis of bone related malignancies ; its mechanisms and experimental treatment
- Principal Investigator
  
  MYOUI Akira
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University

All 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] がんを生きるための骨転移リテラシー2013
- Author(s)
  橋本伸之
- Total Pages
  245
- Publisher
  文芸社
- Data Source
  KAKENHI-PROJECT-23592184
[Journal Article] Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells2012
- Author(s)
  Tomonoga, M., et al.
- Journal Title
  
  Int.J.Oncol.
  
  Volume: 40 Pages: 409-417
- DOI
  10.3892/ijo.2011.1209
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117006, KAKENHI-PROJECT-22249008, KAKENHI-PROJECT-23390070, KAKENHI-PROJECT-23390364, KAKENHI-PROJECT-23657075
[Journal Article] Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells.2011
- Author(s)
  Tomonaga M, Hashimoto N, Tokunaga F, Onishi M, Myoui A, Yoshikawa H, Iwai K.
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 409-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592184
[Journal Article] Evaluation of chemotherapy response in osteosarcoma with FDG-PET2009
- Author(s)
  Hamada K, Tomita Y, Inoue A, Fujimoto T, Hashimoto N, Myoui A, Yoshikawa H, Hatazawa J
- Journal Title
  
  Ann Nucl Med 23(1)
  
  Pages: 89-95
- NAID
  10025135442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591631
[Journal Article] Radio-sensitization of the Murine Osteosarcoma Cell Line LM8 with Parthenolide, a Natural Inhibitor of NF-κB.
- Author(s)
  Sugiyasu K Hashimoto N, Myoui A, Yoshikawa H, et al.
- Journal Title
  
  Oncology Letters. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591754
[Presentation] マウス骨肉腫肺転移における新規NFκB活性化経路(LUBAC)の役割2010
- Author(s)
  友永真人、橋本伸之、名井陽、吉川秀樹, ほか
- Organizer
  第43回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-20591754
[Presentation] マウス骨肉腫肺転移における新規NFκB活性化経路(LUBAC)の役割2010
- Author(s)
  友永真人、橋本伸之、名井陽、吉川秀樹, ほか
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20591754
[Presentation] Radio-sensitization of the Murine Osteosarcoma Cell Line LM8 with Parthenolide, a Natural Inhibitor of NF-κB.2010
- Author(s)
  杉安謙仁朗, 橋本伸之, 名井陽, 吉川秀樹, et al.
- Organizer
  56^<th> annual meetingof orthopaedic research society
- Place of Presentation
  New Orleans, USA.
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-20591754
[Presentation] マウス骨肉腫肺転移における新規NFκB活性化経路(LUBAC)の役割2010
- Author(s)
  友永真人、橋本伸之、名井陽、吉川秀樹, ほか
- Organizer
  第19回日本がん転移学会
- Place of Presentation
  金沢市
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20591754
[Presentation] NFκB阻害剤パルテノライドによるマウス骨肉腫LM8の放射線感受性増強実験2010
- Author(s)
  杉安謙仁朗、橋本伸之、名井陽、吉川秀樹, ほか
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591754
[Presentation] NFκB阻害剤パルテノライドによるマウス骨肉腫LM8の放射線感受性増強実験2010
- Author(s)
  杉安謙仁朗、橋本伸之、名井陽、吉川秀樹, ほか
- Organizer
  第43回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-20591754

1. MYOUI Akira (10263261)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. YOSHIKAWA Hideki (60191558)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. TAKENAKA Satoshi (00588379)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. UEDA Takafumi (00324773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TOMITA Tetsuya (30283766)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKA Norifumi (90601964)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OKAMOTO Mina (50457008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAMAI Noriyuki (60464244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HIGUCHI Chikahisa (40432421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HONDA Hirotsugu (90624213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKASE Takanobu (00283755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鳥塚之嘉 (20324775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YONEDA Toshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NISHIMURA Riko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HIRAGA Toru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ITOH Kazuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ARAKI Nobuhito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TOMITA Yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. KISHIDA Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 田村太資

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 外堀司

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中崎学人

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 吉岡潔子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 藤本哲穂

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 野村幸嗣

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 濱田健一郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 南野勝彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 杉安謙仁朗

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 友永真人

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 富田哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HASHIMOTO Nobuyuki 橋本 伸之

Research Projects

Research Products

Co-Researchers

Optimization of Regeneration Technique for Large Bone Defect

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨肉腫治療標的分子の探索～ラット発癌モデルとマウス肺転移モデルによる解析～Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pre-metastatic Niche and Its Role in Lung Metastasis of Malignant Musculoskeletal TumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of the metastasis of malignant bone tumors and anti-metastasis therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metastasis of bone related malignancies ; its mechanisms and experimental treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] がんを生きるための骨転移リテラシー2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of chemotherapy response in osteosarcoma with FDG-PET2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Radio-sensitization of the Murine Osteosarcoma Cell Line LM8 with Parthenolide, a Natural Inhibitor of NF-κB.

Author(s)

Journal Title

Data Source

[Presentation] マウス骨肉腫肺転移における新規NFκB活性化経路(LUBAC)の役割2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] マウス骨肉腫肺転移における新規NFκB活性化経路(LUBAC)の役割2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Radio-sensitization of the Murine Osteosarcoma Cell Line LM8 with Parthenolide, a Natural Inhibitor of NF-κB.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] マウス骨肉腫肺転移における新規NFκB活性化経路(LUBAC)の役割2010

Author(s)

Organizer

Place of Presentation

Year and Date

HASHIMOTO Nobuyuki 橋本伸之