Yamaji Toshiyuki 山地俊之

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YAMAJI Toshiyuki 山地俊之

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Researcher Number	50332309
Other IDs
Affiliation (Current)	2025: 順天堂大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2024: 順天堂大学, 薬学部, 教授 2015 – 2023: 国立感染症研究所, 細胞化学部, 室長 2014: 国立感染症研究所, その他部局等, 主任研究官 2009 – 2014: National Institute of Infectious Diseases, 細胞化学部, 主任研究官 2008: National Institute of Infectious Diseases, 細胞化学部第二室, 研究員
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Basic Section 49060:Virology-related / Environmental and hygienic pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Functional biochemistry
Keywords	Principal Investigator スフィンゴ糖脂質 / ゲノムワイドスクリーニング / 糖鎖 / 遺伝子編集法 / 糖脂質 / スクリーニング / 代謝 / 脂質 / 志賀毒素 / 血清 … More / リソソーム / ゲノムワイド探索 / CRISPRライブラリー / サルベージ経路 / スフィンゴ脂質 / 膜輸送 / 脂質輸送 / ゴルジ体 / ゲノム編集 / ゲノム編集法 / shRNA / 膜タンパク / FAIM2 / TMBIMファミリー / 細菌毒素 / トランスゴルジネットワーク / 糖転移酵素 … More Except Principal Investigator ゲノム編集 / スクリーニング / Vero細胞 / 感染症 / クラミジア / HeLa細胞 / 脂質輸送 / セラミド / 脂質 / ウイルス受容体 / CRISPR / トゴトウイルス / 細胞改変 / ワクチン産生細胞 / ゲノムワイドスクリーニング / 宿主因子 / 複製 / レプリコン / 黄熱ウイルス / ヒトパピローマウイルス / E2 / FLCN / sgRNAライブラリー / CRISPR-Cas9 / 細胞侵入 / HPV / Huh細胞 / ウイルス感染症 / フラビウイルス / ワクチン / ウイルス / 宿主細胞 / ベロ細胞 / 細胞基材 / プレスクトリン相同ドメイン / クラミジア菌 / 性感染症 / ゲノム / ワクチン細胞基材 / 細胞内寄生 / ホスホイノシチド / プレクストリン相同ドメイン / 輸送 / 生体膜 / スフィンゴ脂質 / タンパク質リン酸化 / ゴルジ体 / 小胞体 / リン酸化 / スフィンゴミエリン / 輸送タンパク質 / 膜輸送 Less

CRISPR全ゲノム探索によるThogotovirus属ウイルスの宿主受容体の同定
- Principal Investigator
  
  本間悠太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Juntendo University
A replicon-based screen of yellow fever virus host factors: Toward generation of highly productive virus-producer cell lines
- Principal Investigator
  
  齊藤恭子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  National Institute of Infectious Diseases
Comprehensive analysis of the sphingolipid recycling pathway based on genome-wide screeningPrincipal Investigator
- Principal Investigator
  
  YAMAJI Toshiyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  National Institute of Infectious Diseases
Omics analysis in human papillomavirus cell entry
- Principal Investigator
  
  Ishii Yoshiyuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
Exploration of Glucosylceramide Transport Factors Using CRISPR LibraryPrincipal Investigator
- Principal Investigator
  
  Yamaji TOshiyuki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Institute of Infectious Diseases
Genomics-based improvement of Vero cells for virus growth
- Principal Investigator
  
  Hanada Kentaro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  National Institute of Infectious Diseases
Search for new factors involved in glycolipid metabolism and transport by a genome-wide shRNA screenPrincipal Investigator
- Principal Investigator
  
  Yamaji Toshiyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Institute of Infectious Diseases
Molecular strategy for the prevention of Chlamydia hijacking of a host lipid transport system
- Principal Investigator
  
  HANADA KENTARO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  National Institute of Infectious Diseases
Regulation of glycosphingolipids biosynthesis by multi-spanning transmembrane protein family TMBIMs and their molecular machineryPrincipal Investigator
- Principal Investigator
  
  YAMAJI Toshiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Institute of Infectious Diseases
Regulatory mechanism of intracellular trafficking of ceramide
- Principal Investigator
  
  HANADA KENTARO
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Institute of Infectious Diseases
A genetic biochemical search and analysis for factors involved in glycosphingolipid metabolism and trafficPrincipal Investigator
- Principal Investigator
  
  YAMAJI Toshiyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Institute of Infectious Diseases

[Journal Article] Construction of Sphingolipid Remodeled Cells by Genome Editing2023
- Author(s)
  Yamaji T, Homma Y
- Journal Title
  
  Method Mol Biol
  
  Volume: 2613 Pages: 111-125
- DOI
  10.1007/978-1-0716-2910-9_10
- ISBN
  9781071629093, 9781071629109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02435
[Journal Article] Involvement of a cluster of basic amino acids in phosphorylation-dependent functional repression of the ceramide transport protein CERT2022
- Author(s)
  Goto A, Egawa D, Tomishige N, Yamaji T, Shimasaki K, Kumagai K, Hanada K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 15 Pages: 8576-8576
- DOI
  10.3390/ijms23158576
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02435
[Journal Article] Compartmentalization of casein kinase 1 γ CSNK1G controls the intracellular trafficking of ceramide2022
- Author(s)
  Goto A, Sakai s, Mizuike A, Yamaji T, Hanada K
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 7 Pages: 164624-164624
- DOI
  10.1016/j.isci.2022.104624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02435, KAKENHI-WRAPUP-22H04899, KAKENHI-PLANNED-17H06417
[Journal Article] Hyperosmotic Stress Induces Phosphorylation of CERT and Enhances Its Tethering Throughout the Endoplasmic Reticulum2022
- Author(s)
  Shimasaki K, Kumagai K, Sakai S, Yamaji T, Hanada K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 7 Pages: 4025-4025
- DOI
  10.3390/ijms23074025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02435, KAKENHI-WRAPUP-22H04899, KAKENHI-PLANNED-17H06417
[Journal Article] Poliovirus-nonsusceptible Vero cell line for the World Health Organization global action plan2021
- Author(s)
  Okemoto-Nakamura Y, Someya K, Yamaji T, Saito K, Takeda M, Hanada K
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 6746-6746
- DOI
  10.1038/s41598-021-86050-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-17H04003
[Journal Article] Golgi maturation-dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3.2021
- Author(s)
  Riccardo Rizzo, Domenico Russo, Kazuo Kurokawa, Alfredo Budillon, Franck Perez, Seetharaman Parashuraman, Yusuf A Hannun, Akihiko Nakano, Daniela Corda, Giovanni D’Angelo and Alberto Luini et al.,.
- Journal Title
  
  The EMBO Journal
  
  Volume: 40 Issue: 8
- DOI
  10.15252/embj.2020107238
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06650, KAKENHI-PLANNED-17H06420, KAKENHI-PROJECT-18H05275, KAKENHI-PROJECT-17K07357, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
[Journal Article] Galabiosylceramide is present in human cerebrospinal fluid2021
- Author(s)
  Akiyama H, Ide M, Yamaji T, Mizutani Y, Niimi Y, Mutoh T, Kamiguchi H, Hirabayashi Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 536 Pages: 73-79
- DOI
  10.1016/j.bbrc.2020.12.051
- Data Source
  KAKENHI-PROJECT-17K07357
[Journal Article] Identification of SYS1 as a Host Factor Required for Shiga Toxin-Mediated Cytotoxicity in Vero Cells2021
- Author(s)
  Sakuma Chisato、Sekizuka Tsuyoshi、Kuroda Makoto、Hanada Kentaro、Yamaji Toshiyuki
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 9 Pages: 4936-4936
- DOI
  10.3390/ijms22094936
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-18K14912, KAKENHI-PROJECT-21H02435, KAKENHI-PLANNED-17H06417
[Journal Article] Concise and Reliable Syntheses of Glycodendrimers via Self-Activating Click Chemistry: A Robust Strategy for Mimicking Multivalent Glycan?Pathogen Interactions2020
- Author(s)
  Farabi K, Manabe Y, Ichikawa H, Miyake S, Tsutsui M, Kabayama K, Yamaji T, Tanaka K, Hung S-C, Fukase K.
- Journal Title
  
  J Org Chem
  
  Volume: 85 Issue: 24 Pages: 16014-16023
- DOI
  10.1021/acs.joc.0c01547
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-20K05727, KAKENHI-PLANNED-15H05836, KAKENHI-PROJECT-16H05924, KAKENHI-PUBLICLY-20H04709, KAKENHI-PROJECT-20H05675
[Journal Article] Identification of Characteristic Genomic Markers in Human Hepatoma HuH-7 and Huh7.5.1-8 Cell Lines2020
- Author(s)
  Kawamoto M#, Yamaji T#, Saito K, Shirasago Y, Satomura K, Endo T, Fukasawa M, Hanada K, Osada N.
- Journal Title
  
  Front Genet
  
  Volume: 11 Pages: 546106-546106
- DOI
  10.3389/fgene.2020.546106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-17H04003
[Journal Article] Blood group P1 antigen?bearing glycoproteins are functional but less efficient receptors of Shiga toxin than conventional glycolipid-based receptors2020
- Author(s)
  Morimoto K, Suzuki N, Tanida I, Kakuta S, Furuta Y, Uchiyama Y, Hanada K, Suzuki Y, Yamaji T.
- Journal Title
  
  J Biol Chem
  
  Volume: 295 Issue: 28 Pages: 9490-9501
- DOI
  10.1074/jbc.ra120.013926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-20K06520, KAKENHI-PUBLICLY-20H05342, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
[Journal Article] Preparation of Fluorescent Recombinant Shiga Toxin B Subunit and Its Application to Flow Cytometry2020
- Author(s)
  Yamaji T
- Journal Title
  
  Methods Mol Biol,
  
  Volume: 2132 Pages: 463-474
- DOI
  10.1007/978-1-0716-0430-4_45
- ISBN
  9781071604298, 9781071604304
- Data Source
  KAKENHI-PROJECT-17K07357
[Journal Article] Comparative characterization of flavivirus production in two cell lines: Human hepatoma-derived Huh7.5.1-8 and African green monkey kidney-derived Vero2020
- Author(s)
  Kyoko Saito, Masayoshi Fukasawa, Yoshitaka Shirasago, Ryosuke Suzuki, Naoki Osada, Toshiyuki Yamaji, Takaji Wakita, Eiji Konishi, Kentaro Hanada
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 4 Pages: e0232274-e0232274
- DOI
  10.1371/journal.pone.0232274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08362, KAKENHI-PROJECT-17K07357, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-17H04003
[Journal Article] Sphingomyelin Is Essential for the Structure and Function of the Double-Membrane Vesicles in Hepatitis C Virus RNA Replication Factories2020
- Author(s)
  Gewaid H, Aoyagi H, Arita M, Watashi K, Suzuki R, Sakai S, Kumagai K, Yamaji T, Fukasawa M, Kato F, Hishiki T, Mimata A, Sakamaki Y, Ichinose S, Hanada K, Muramatsu M, Wakita T, Aizaki H.
- Journal Title
  
  J Virol
  
  Volume: 94 Issue: 23
- DOI
  10.1128/jvi.01080-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-20K07532, KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-17K08870
[Journal Article] A CRISPR screen identifies LAPTM4A and TM9SF proteins as glycolipid-regulating factors2019
- Author(s)
  Yamaji T, Sekizuka T, Tachida Y, Sakuma C, Morimoto K, Kuroda M, Hanada K
- Journal Title
  
  iScience
  
  Volume: 11 Pages: 409-424
- DOI
  10.1016/j.isci.2018.12.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PLANNED-17H06417
[Journal Article] 哺乳動物のセラミド関連脂質生合成2019
- Author(s)
  山地俊之
- Journal Title
  
  セラミド研究の新展開～基礎から応用へ～
  
  Volume: 0 Pages: 22-31
- Data Source
  KAKENHI-PROJECT-17K07357
[Journal Article] A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-Regulating Factor2019
- Author(s)
  Yamaji Toshiyuki、Hanamatsu Hisatoshi、Sekizuka Tsuyoshi、Kuroda Makoto、Iwasaki Norimasa、Ohnishi Makoto、Furukawa Jun-ichi、Yahiro Kinnosuke、Hanada Kentaro
- Journal Title
  
  iScience
  
  Volume: 15 Pages: 407-420
- DOI
  10.1016/j.isci.2019.05.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-19K07534, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
[Journal Article] Chlamydia trachomatis‐infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 22019
- Author(s)
  Tachida Yuriko、Kumagai Keigo、Sakai Shota、Ando Shuji、Yamaji Toshiyuki、Hanada Kentaro
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 3 Pages: 519-529
- DOI
  10.1002/1873-3468.13632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-18K06649, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
[Journal Article] Nanotubes connecting B lymphocytes: High impact of differentiation-dependent lipid composition on their growth and mechanics2017
- Author(s)
  Toth EA, Oszvald A, Peter M, Balogh G, Osteikoetxea- Molnar A, Bozo T, Szabo-Meleg E, Nyitrai M, Derenyi I, Yamaji T, Hanada K, Vigh L, Matko J
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1862 Issue: 9 Pages: 991-1000
- DOI
  10.1016/j.bbalip.2017.06.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07357
[Journal Article] Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide2016
- Author(s)
  Yamaji T, Horie A, Tachida Y, Sakuma C, Suzuki Y, Kushi Y, Hanada K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 17 Issue: 10 Pages: 1761-1761
- DOI
  10.3390/ijms17101761
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440069
[Journal Article] Sphingolipid metabolism and interorganellar transport: localization of sphingolipid enzymes and lipid transfer proteins2015
- Author(s)
  Toshiyuki Yamaji and Kentaro Hanada
- Journal Title
  
  Traffic
  
  Volume: 16 Issue: 2 Pages: 101-122
- DOI
  10.1111/tra.12239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460086, KAKENHI-PROJECT-25670065, KAKENHI-PROJECT-26440069
[Journal Article] Establishment of HeLa cell mutants deficient in sphingolipid- related genes using TALENs2014
- Author(s)
  Yamaji T, Hanada K.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770164
[Journal Article] Establishment of HeLa cell mutants deficient in sphingolipid-related genes by using TALENs2014
- Author(s)
  Yamaji T, and Hanada K
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 2 Pages: e88124-e88124
- DOI
  10.1371/journal.pone.0088124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370054, KAKENHI-PROJECT-23770164, KAKENHI-PROJECT-25670065
[Journal Article] The genome landscape of the African green monkey kidney-derived Vero cell line.2014
- Author(s)
  Osada N, Kohara A, Yamaji T, Hirayama N, Kasai F, Sekizuka T, Kuroda M, Hanada K
- Journal Title
  
  DNA Res.
  
  Volume: 21 Issue: 6 Pages: 673-683
- DOI
  10.1093/dnares/dsu029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23113008, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-25670065, KAKENHI-PROJECT-26251040, KAKENHI-PROJECT-26440069
[Journal Article] Binding of a sialic acid-recognizing lectin Siglec-9 modulates adhesion dynamics of cancer cells via calpain-mediated protein degradation2013
- Author(s)
  Sabit I, Hashimoto N, Matsumoto Y, Yamaji T, Furukawa K, Furukawa K.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 35417-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770164
[Journal Article] Binding of a sialic acid-recognizing lectin Siglec-9 modulates adhesion dynamics of cancer cells via calpain-mediated protein degradation.2013
- Author(s)
  Sabit I.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288 Issue: 49 Pages: 35417-27
- DOI
  10.1074/jbc.m113.513192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23770164, KAKENHI-PROJECT-24390078
[Journal Article] Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing2013
- Author(s)
  Kukimoto I, Maehama T, Sekizuka T, Ogasawara Y, Kondo K, Kusumoto-Matsuo R, Mori S, Ishii Y, Takeuchi T, Yamaji T, Takeuchi F, Hanada K, Kuroda M.
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770164
[Journal Article] Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors, siglec-7 and-92012
- Author(s)
  Miyazaki, K., Sakuma, K., Kawamura, Y. I., Izawa, M., Ohmori, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Suzuki, A., Saito, Y., Dohi, T., and Kannagi, R.
- Journal Title
  
  J. Immunol
  
  Volume: 188 Issue: 9 Pages: 4690-4700
- DOI
  10.4049/jimmunol.1100605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590324, KAKENHI-PROJECT-22590712, KAKENHI-PROJECT-22790774, KAKENHI-PUBLICLY-23112520, KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-23770164
[Journal Article] Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT)2012
- Author(s)
  Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, Takahashi H, and Shimada I
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 40 Pages: 33706-33718
- DOI
  10.1074/jbc.m112.367730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370054, KAKENHI-PROJECT-23770164, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-23790118, KAKENHI-PROJECT-24370048, KAKENHI-PROJECT-24890263, KAKENHI-PUBLICLY-23107735, KAKENHI-PUBLICLY-24102524
[Journal Article] "3D Modeling of a Natural Killer Receptor, Siglec-7 : Critical Amino Acids for Glycan-Binding and Cell Death-Inducing Activity"「Modeling and Simulation in Engineering」2012
- Author(s)
  Yamaji T., Yamaguchi Y., Mitsuki M., Takashima S., Waguri S., Hashimoto Y., Nara K.
- Journal Title
  
  INTECH
  
  Volume: (ISBN : 978-953-307- 959-2, 103-116)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770164
[Journal Article] Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT)2012
- Author(s)
  Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, Takahashi H, Shimada I.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 33706-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770164
[Journal Article] Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors siglec-7 and -92012
- Author(s)
  Miyazaki K, Sakuma K, Kawamura YI, Izawa M, Ohmori K, Mitsuki M, Yamaji T, Hashimoto Y, Suzuki A, Saito Y, Dohi T, Kannagi R.
- Journal Title
  
  J Immunol
  
  Volume: 188 Pages: 4690-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770164
[Journal Article] 3D Modeling of a Natural Killer Receptor, Siglec-7: Critical Amino Acids for Glycan-Binding and Cell Death-Inducing Activity2011
- Author(s)
  Yamaji T., Yamaguchi Y., Mitsuki M., Takashima S., Waguri S., Hashimoto Y., and Nara K.
- Journal Title
  
  「Modeling and Simulation in Engineering, INTECH
  
  Volume: ISBN: 978-953-307-959-2 Pages: 103-116
- DOI
  10.5772/31157
- ISBN
  9789535100126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770164
[Journal Article] Siglec-7 mediates nonapoptotic cell death independently of its immunoreceptor tyrosine-based inhibitory motifs in monocytic cell line U9372010
- Author(s)
  Mitsuki, M., Nara, K., Yamaji, T., Enomoto, A., Kanno, M., Yamaguchi, Y., Yamada, A., Waguri, S., Hashimoto, Y.
- Journal Title
  
  Glycobiology 20(3)
  
  Pages: 395-402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturb a trans-Golgi network enzyme, Gb3 synthase, and reduce Gb3 biosynthesis.2010
- Author(s)
  Yamaji, T., Nishikawa, K., Hanada, K.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 35505-35518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] Siglec-7 mediates non-apoptotic cell death independently of its immunoreceptor tyrosine-based inhibitory motifs in monocytic cell line U937.2010
- Author(s)
  Mitsuki, M., Nara, K., Yamaji, T., Enomoto A., Kanno, M., Yamaguchi, Y., Yamada, A., Waguri, S., Hashimoto, Y. (equal contribution)
- Journal Title
  
  Glycobiology 20
  
  Pages: 395-402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturb a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis2010
- Author(s)
  Yamaji T, Nishikawa K, and Hanada K
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Issue: 46 Pages: 35505-35518
- DOI
  10.1074/jbc.m110.154229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370054
[Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis2010
- Author(s)
  Toshiyuki Yamaji
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 285 Pages: 35505-35518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370054
[Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis2010
- Author(s)
  Yamaji, T., Nishikawa, K., Hanada, K.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 35505-35518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] CERT-mediated trafficking of ceramide.2009
- Author(s)
  Hanada, K., Kumagai, K., Tomishige, N., Yamaji, T.
- Journal Title
  
  Biochim. Biophys.A cta 1791
  
  Pages: 684-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] CERT-mediated trafficking of ceramide2009
- Author(s)
  Hanada, K., Kumagai, K., Tomishige, N., Yamaji, T.
- Journal Title
  
  Biochim Biophys Acta. 1791(7)
  
  Pages: 684-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] CERT-mediated trafficking of ceramide2009
- Author(s)
  Hanada, K., Kumagai, K., Tomishige, N., and Yamaji, T.
- Journal Title
  
  Biochim Biophys Acta. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] Two sphingolipid transfer proteins, CERT and FAPP2 : Their roles in sphingolipid metabolism.2008
- Author(s)
  Yamaji, T., Kumagai, K., Tomishige, N., Hanada, K.
- Journal Title
  
  IUBMB Life 60
  
  Pages: 511-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Journal Article] Two sphingolipid transfer proteins, CERT and FAPP2 : Their roles in sphingolimd metabolism2008
- Author(s)
  Yamaji, T., Kumagai, K., Tomishige, N., and Hanada, K.
- Journal Title
  
  IUBMB Life. 60(8)
  
  Pages: 511-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] C10orf76-PI4KB軸によって遠位ゴルジ体へのCERT依存性セラミド輸送が組織化される2022
- Author(s)
  水池　彩、酒井祥太、加藤薫、山地俊之、花田賢太郎
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] 小胞体-ゴルジ体間セラミド輸送の場の多様性2022
- Author(s)
  水池　彩、酒井祥太、加藤薫、山地俊之、花田賢太郎
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] ヒトマクロファージによる抗酸菌の殺菌機構における極長鎖脂肪酸鎖を有するスフィンゴ脂質の役割について2022
- Author(s)
  花房慶、中山仁志、山地俊之、岩渕和久
- Organizer
  第15回セラミド研究会学術集会・第16回スフィンゴテラピィ研究会合同年会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] Casein kinase 1γの分布区画化が小胞体―ゴルジ体間セラミド輸送を制御する2022
- Author(s)
  後藤麻子、酒井祥太、水池彩、山地俊之、花田賢太郎
- Organizer
  第15回セラミド研究会学術集会・第16回スフィンゴテラピィ研究会合同年会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] 極長鎖セラミド依存的なネクロプトーシスの誘導2022
- Author(s)
  北谷和之、小木曽悠里、山澤龍治、伊藤潔、松田将也、山地俊之、花田賢太郎、坂本渉、Daniel Canals、Yusuf A. Hannun、奈邉健
- Organizer
  第15回セラミド研究会学術集会・第16回スフィンゴテラピィ研究会合同年会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] カゼインキナーゼ 1γ の C 末端脂質修飾に依存した細胞内局在変化がスフィンゴミエリン生合成におけるセラミド輸送を制御する2022
- Author(s)
  後藤麻子、酒井祥太、水池彩、山地俊之、花田賢太郎
- Organizer
  第64回脂質生化学会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] カゼインキナーゼ1γのC末端領域依存的な細胞内局在の変化がスフィンゴミエリン生合成におけるセラミド輸送に影響を及ぼす2021
- Author(s)
  後藤麻子, 水池彩, 山地俊之, 花田賢太郎
- Organizer
  第73回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] 合成糖鎖提示手法を用いた糖鎖－ガレクチン相互作用によるタンパク質動態制御2021
- Author(s)
  三浦彩音、樺山一哉、真鍋良幸、三宅秀斗、白川明日香、初村洋紀、山地俊之、鈴木健一、深瀬浩一
- Organizer
  第15回ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] ANXA1をキャリアとした細胞内で作用する標的結合タンパク質の創出2021
- Author(s)
  内野美佳子、黒澤静霞、山地俊之、相川京子
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] ゲノム編集法を用いた生体膜脂質や糖鎖の代謝及び感染症研究2021
- Author(s)
  山地俊之
- Organizer
  東京医科歯科大学大学院特別セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] ゲノムワイドCRISPRスクリーニングによるHPV細胞侵入に必要な宿主因子の同定2021
- Author(s)
  石井克幸、山地俊之、本間悠太、関塚剛史
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-18K07154
[Presentation] Application of genome editing technologies to studies on sphingolipid biology2021
- Author(s)
  山地俊之
- Organizer
  第141回日本薬学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] 小胞体-ゴルジ体間セラミド輸送ゾーンの形成に重要なPI4KB結合因子の解析2021
- Author(s)
  水池彩、酒井祥太、加藤薫、山地俊之、花田賢太郎
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] Quantitative Analysis of Galectin-dependent Glycoprotein Dynamics by using Synthetic Glycan Displaying System on the Cell Surface2021
- Author(s)
  Ayane Miura, Kazuya Kabayama, Yoshiyuki Manabe, Shuto Miyake, Asuka Shirakawa, Hiroki Shomura, Toshiyuki Yamaji, Kenichi G.N. Suzuki, Koichi Fukase
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] ヒト脳脊髄液には志賀毒素と反応する新奇糖脂質が存在する2021
- Author(s)
  秋山央子、山地俊之、水谷泰彰、新美芳樹、武藤多津郎、上口裕之、平林義雄
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] 8.Modulation of Zika virus replication via glucosylceramide 1 synthase and glycosphingolipids2021
- Author(s)
  Brown M, Cerone J, Ogbamikael S, Yager E, Yamaji T, Barroso M, Hanada K, Konan K
- Organizer
  Eastern Society for Pediatric Research Annual Meeting ESPR2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] 生細胞表層への合成糖鎖導入および糖鎖-レクチン相互作用の分子化学的解析2021
- Author(s)
  三浦彩音、樺山一哉、真鍋良幸、三宅秀斗、白川明日香、初村洋紀、山地俊之、鈴木健一、深瀬浩一
- Organizer
  第40回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21H02435
[Presentation] P1糖鎖エピトープを有する糖タンパク質の志賀毒素受容体としての機能解析2020
- Author(s)
  森本貫太、鈴木詔子、谷田以誠、角田宗一郎、古田陽子、内山安男、花田賢太郎、鈴木佑典、山地俊之
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] ヒト脳脊髄液にはガラビオシルセラミド（Gb2）が存在する2020
- Author(s)
  秋山央子、井出三津子、山地俊之、植田晃広、新美芳樹、武藤多津郎、上口裕之、平林義雄
- Organizer
  第62回脂質生化学会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] 小胞体-ゴルジ体連携ゾーンにおけるCERTの機能制御に関する因子の探索2020
- Author(s)
  水池彩、酒井祥太、山地俊之、花田賢太郎
- Organizer
  第62回脂質生化学会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] スフィンゴ脂質のC型肝炎ウイルス複製における役割の解析2020
- Author(s)
  相崎英樹、青柳東代、若江亨祥、有田峰太郎、渡士幸一、鈴木亮介、熊谷圭悟、山地俊之、深澤征義、村松正道、脇田隆字、花田賢太郎
- Organizer
  第62回脂質生化学会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] ヒトマクロファージの免疫応答における極長鎖脂肪酸鎖を含むスフィンゴ脂質の役割2020
- Author(s)
  花房慶、中山仁志、山地俊之、岩渕和久
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] CRISPRライブラリーを用いたSubtilase cytotoxinによる致死に耐性を示す細胞の樹立と受容体認識機構の解明2019
- Author(s)
  八尋錦之助、大西真、花田賢太郎、山地俊之
- Organizer
  第23回腸管出血性大腸菌研究会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] 糖鎖結合性細菌毒素を用いたゲノムワイドCRISPRスクリーニング2019
- Author(s)
  山地俊之
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] P1糖鎖エピトープを有した糖タンパク質の志賀毒素受容体としての機能解析2019
- Author(s)
  森本貫太、鈴木詔子、花田賢太郎、鈴木佑典、山地俊之
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] Application of genome editing technologies to studies on sphingolipid and glycan metabolisms2019
- Author(s)
  Toshiyuki Yamaji
- Organizer
  1st Japan-Europe Workshop on Glycosphingolipids and Membrane homeostatsis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] ゲノムワイドCRISPR/Cas9スクリーニングシステムのin silico解析webアプリケーション2019
- Author(s)
  関塚剛史、佐久間智理、糸川健太郎、花田賢太郎、黒田誠、山地俊之
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] ゲノムワイドスクリーニングによって同定された糖鎖発現制御因子の解析2019
- Author(s)
  山地俊之、関塚剛史、花松久寿、黒田誠、古川潤一、八尋錦之助、花田賢太郎
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] Genome-wide CRISPR screens identify novel glycan regulators2019
- Author(s)
  Toshiyuki Yamaji, Tsuyoshi Sekizuka, Hisatoshi Hanamatsu, Makoto Kuroda, Jun-ichi Furukawa, Kinnosuke Yahiro, Kentaro Hanada
- Organizer
  25th International Symposium on Glycoconjugates
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] Chlamydia trachomatisは細胞内寄生に宿主のスフィンゴミエリン生合成を必要としない2018
- Author(s)
  立田由里子, 熊谷圭悟, 酒井祥太, 山地俊之, 花田賢太郎
- Organizer
  第60回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] Genome-Wide CRISPR Screening for Identifying Genes Involved in Glycolipid Metabolism2018
- Author(s)
  Yamaji T, Hanada K
- Organizer
  Gordon Research Conference on Glycolipid and Sphingolipid Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] 遺伝子編集法を用いた宿主細胞因子の探索及び糖鎖生合成研究への応用2018
- Author(s)
  山地俊之
- Organizer
  第16回糖鎖科学コンソーシアムシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] Chlamydia trachomatisは細胞内寄生に宿主のスフィンゴミエリン生合成を必要としない2018
- Author(s)
  立田由里子, 熊谷圭悟, 酒井祥太, 山地俊之, 花田賢太郎
- Organizer
  第11回セラミド研究会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] ゲノム編集法を用いた糖鎖・脂質代謝関連因子の探索2018
- Author(s)
  山地俊之
- Organizer
  第2回オルガネラゾーン研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] CRISPRライブラリーを用いた糖脂質生合成に影響を及ぼす因子の探索2017
- Author(s)
  山地俊之、関塚剛史、佐久間智理、立田由里子、黒田誠、花田賢太郎
- Organizer
  2017年度生命科学系学会合同年次大会第40回日本分子生物学会年会・第90回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] CRISPRライブラリーを用いた志賀毒素の細胞障害作用に対するゲノムワイドスクリーニング2017
- Author(s)
  山地俊之、立田由里子、佐久間智理、関塚剛史、黒田誠、花田賢太郎
- Organizer
  第59回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-17K07357
[Presentation] HaloTagテクノロジーを用いた細胞表面へのGb3糖鎖提示システムの構築と評価2016
- Author(s)
  三宅秀斗，樺山一哉，真鍋良幸，Siyu Chen，山地俊之，花田賢太郎，深瀬浩一
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  京田辺
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] Application of genome editing technologies for studies on sphingolipid and glycan metabolisms2016
- Author(s)
  Toshiyuki Yamaji, Tsuyoshi Sekizuka, Kinnosuke Yahiro, Yuriko Tachida, Chisato Sakuma, Makoto Kuroda, Kentaro Hanada
- Organizer
  EMBO Workshop “Glycosylation in the Golgi complex”
- Place of Presentation
  Vico Equense, Italy
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] ゲノム編集技術を用いたスフィンゴ脂質・糖鎖の代謝研究2016
- Author(s)
  山地　俊之、関塚　剛史、八尋　錦之助、鈴木　佑典、櫛　泰典、黒田　誠、花田賢太郎
- Organizer
  第３５回日本糖質学会年会
- Place of Presentation
  高知
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] Chlamydia hijacking of the host cell CERT2015
- Author(s)
  Kentaro Hanada, Toshiyuki Yamaji, Keigo Kumagai
- Organizer
  第10回スフィンゴテラピィ研究会
- Place of Presentation
  金沢
- Year and Date
  2015-06-16
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] 慢性骨髄性白血病細胞株K562細胞の膜脂質組成によるγ-グロビン発現制御機構2015
- Author(s)
  田村恭祐、鈴木佑典、山地俊之、長谷川拓馬、稲岡夏希、野崎真李果、櫛泰典
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] クラミジア・トラコマティスによってハイジャックされる宿主セラミド輸送機構2015
- Author(s)
  熊谷圭悟、山地俊之、山本章嗣、花田賢太郎
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] 志賀毒素の細胞障害作用を指標としたゲノムワイドshRNAスクリーニング2015
- Author(s)
  山地俊之、堀江亜矢、関塚剛史、竹内史比古、黒田誠、花田賢太郎
- Organizer
  第57回脂質生化学会
- Place of Presentation
  東京
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] 志賀毒素の細胞傷害作用に対するゲノムワイドshRNAスクリーニング2014
- Author(s)
  堀江亜矢、関塚剛史、竹内史比古、黒田誠、花田賢太郎、山地俊之
- Organizer
  第８７回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] TALEN-mediated disruption of several sphingolipid-related genes in a HeLa cell line2014
- Author(s)
  Yamaji T, and Hanada K
- Organizer
  Gordon Research Conference on Glycolipid and Sphingolipid Biology
- Place of Presentation
  Ventura, CA, USA
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] Genetic approaches for studying sphingolipid metabolism: Construction of sphingolipid gene disruptants in HeLa cells by genome editing2014
- Author(s)
  Yamaji T, Hanada K
- Organizer
  6th Asian Community of Glycoscience and Glycotechnology
- Place of Presentation
  Hyderabad, India
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] TALEN-Mediated Disruption of Several Sphingolipid-Related Genes in a HeLa cell line2014
- Author(s)
  Toshiyuki Yamaji and Kentaro Hanada
- Organizer
  Gordon Research Conference on Glycolipid and Sphingolipid Biology
- Place of Presentation
  Ventura, California, USA
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line."2014
- Author(s)
  Yamaji T, Hanada K.
- Organizer
  Gordon Research Conference on Glycolipid and Sphingolipid Biology
- Place of Presentation
  Ventura, USA
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2014
- Author(s)
  Yamaji T, Hanada K
- Organizer
  Gordon Research Conference on Glycolipid and Sphingolipid Biology
- Place of Presentation
  Ventura, USA
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] アフリカミドリザル腎由来Vero細胞のゲノム構造決定2014
- Author(s)
  花田賢太郎、山地俊之、黒田誠、関塚剛史、小原有弘、笠井文生、平山知子、長田直樹
- Organizer
  第８７回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26440069
[Presentation] TALEN-Mediated Disruption of Several Sphingolipid-Related Genes in a HeLa cell line2014
- Author(s)
  Toshiyuki Yamaji and Kentaro Hanada
- Organizer
  Gordon Research Conference on Glycolipid and Sphingolipid Biology
- Place of Presentation
  Ventura, CA, USA
- Data Source
  KAKENHI-PROJECT-25670065
[Presentation] 人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第32回日本糖質学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25670065
[Presentation] "人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa細胞変異株パネル作成の試み"2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第8回スフィンゴテラピィ研究会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa細胞変異株パネル作成の試み2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第８回スフィンゴテラピー研究会
- Place of Presentation
  加賀
- Data Source
  KAKENHI-PROJECT-25670065
[Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013
- Author(s)
  Yamaji, Y., Hanada, K.
- Organizer
  54th International Conference on the Bioscience of Lipids
- Place of Presentation
  Bari, Italy
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] "人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製"2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013
- Author(s)
  Toshiyuki Yamaji and Kentaro Hanada
- Organizer
  54th International Conference on the Bioscience of Lipids: Linking Transcription to Physiology in Lipidomics
- Place of Presentation
  Bari, Italy
- Data Source
  KAKENHI-PROJECT-25670065
[Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013
- Author(s)
  山地俊之, 花田賢太郎
- Organizer
  第86回日生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] TALEN- Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line."2013
- Author(s)
  Yamaji Y, Hanada K.
- Organizer
  54^<th> International Conference on the Bioscience of Lipids
- Place of Presentation
  Bari, Italy
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013
- Author(s)
  Yamaji T, and Hanada K
- Organizer
  54th International Conference on the Bioscience of Lipids : Linking Transcription to Physiology in Lipidomics
- Place of Presentation
  Bari, Italy
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] 人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第32回日本糖質学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] Biding of Siglec-9 to the counter-receptors on cancer cells regulates adhesion dynamics via protease-mediated degradation of focal adhesion kinase (FAK)2013
- Author(s)
  Yilihamujiang, S., Hashimoto, N., Matsumoto, Y., Hashimoto, Y., Yamaji, T., Furukawa, K., Furukawa, K.
- Organizer
  第８６回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013
- Author(s)
  Toshiyuki Yamaji and Kentaro Hanada
- Organizer
  54th International Conference on the Bioscience of Lipids: Linking Transcription to Physiology in Lipidomics
- Place of Presentation
  Bari, Italy
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] "遺伝生化学的手法を用いたスフィンゴ糖脂質研究"2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa細胞変異株パネル作成の試み2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第8回スフィンゴテラピー研究会
- Place of Presentation
  加賀
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] "人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製"2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  松島
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊:HeLa細胞変異株パネル作成の試み2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第8回スフィンゴテラピィ研究会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013
- Author(s)
  山地俊之, 花田賢太郎
- Organizer
  第55回日本脂質生化学会大会
- Place of Presentation
  松島
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] 人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  松島
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] Biding of Siglec-9 to the counter-receptors on cancer cells regulates adhesion dynamics via protease-mediated degradation of focal adhesion kinase (FAK)."2013
- Author(s)
  Yilihamujiang S, Hashimoto N, Matsumoto Y, Hashimoto Y, Yamaji T, Furukawa K, Furukawa K.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 人工ヌクレアーゼTALEN を用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013
- Author(s)
  山地俊之, 花田賢太郎
- Organizer
  第32回日本糖質学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] 人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第３２回日本糖質学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第55回日本脂質生化学会大会
- Place of Presentation
  松島
- Data Source
  KAKENHI-PROJECT-25670065
[Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa 細胞変異株パネル作成の試み2013
- Author(s)
  山地俊之,花田賢太郎
- Organizer
  第8回スフィンゴテラピー研究会
- Place of Presentation
  加賀
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013
- Author(s)
  山地俊之、花田賢太郎
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25670065
[Presentation] "podocalyxin上のO-glycanは癌の免疫逃避を促進する"2012
- Author(s)
  南部今日子、橋本登、伊藤静香、山地俊之、橋本康弘、古川圭子、古川鋼一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] Structural basis for the preferential recognition of phosphatidylinositol 4-monophosphate by the pleckstrin homology domain of the ceramide trafficking protein CERT2012
- Author(s)
  Hanada K, Sugiki T, Takeuchi K, Tokunaga, Y, Terasawa, H, Kumagai, K, Yamaji, T, Takahashi, H, Shimada, I
- Organizer
  2012 ASBMB Special Symposium, Frontiers in Lipid Biology
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] podocalyxin上のO-glycanは癌の免疫逃避を促進する2012
- Author(s)
  南部今日子、橋本登、伊藤静香、山地俊之、橋本康弘、古川圭子、古川鋼一
- Organizer
  第８５回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] Structural basis for the recognition of phosphatidylinositol 4-monophosphate by the pleckstrin homology domain of the ceramide trafficking protein CERT2012
- Author(s)
  Kentaro Hanada, Toshihiko Sugiki, Koh Takeuchi, Yuji Tokunaga, Hiroaki Terasawa, Keigo Kumagai, Toshiyuki Yamaji, Hideo Takahashi, and Ichio Shimada
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] セラミド輸送タンパク質CERTのプレクストリン相同ドメインによるホスファチジルイノシトール４ーリン酸認識の構造基盤2012
- Author(s)
  花田賢太郎、杉木俊彦、竹内恒、山地俊之、高野等覚、徳永祐二、熊谷圭吾、高橋栄夫、嶋田一夫
- Organizer
  第８５回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 糖脂質再構成細胞における膜流動性と成長因子受容体の関連2012
- Author(s)
  櫻井祐介、山地俊之、花田賢太郎、樺山一哉
- Organizer
  第８５回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] "セラミド輸送タンパク質CERTのプレクストリン相同ドメインによるホスファチジルイノシトール4ーリン酸認識の構造基盤"2012
- Author(s)
  花田賢太郎、杉木俊彦、竹内恒、山地俊之、高野等覚、徳永祐二、熊谷圭吾、高橋栄夫、嶋田一夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 糖脂質再構成細胞における膜流動性と成長因子受容体の関連2012
- Author(s)
  櫻井祐介、山地俊之、花田賢太郎、樺山一哉
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] TMBIMファミリーの糖脂質生合成への影響とその制御機構2011
- Author(s)
  山地俊之、西川喜代孝、花田賢太郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 糖鎖受容体Siglec-7を介する細胞死の分子機構の解明2011
- Author(s)
  奈良清光、三ツ木元章、榎本綾子、菅野真由美、山口芳樹、二川了次、城谷圭朗、山地俊之、山田茜、和栗聡
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] Siglec-7 induces non-apoptotic cell death of U9372011
- Author(s)
  Nara K, Mitsuki M, Yamaji T, Enomoto A, Kanno M, Yamaguchi Y, Yamada Y, Waguri S, Hashimoto Y.
- Organizer
  The 31^<th> Naito Conference on Glycan expression and Regulation [II]
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 糖脂質再構成細胞における受容体活性と膜流動性の関連性の解析2011
- Author(s)
  櫻井祐介、山地俊之、花田賢太郎、樺山一哉
- Organizer
  第８４回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] TMBIMファミリーの糖脂質生合成への影響とその制御機構2011
- Author(s)
  山地俊之、西川喜代孝、花田賢太郎
- Organizer
  第８４回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23770164
[Presentation] 糖鎖受容体Siglec-7を解する細胞死の分子機構の解明2010
- Author(s)
  奈良清光、三ツ木元章、榎本綾子、菅野真由美、山口芳樹、二川了次、城谷圭朗、山地俊之、山田茜、和栗聡
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010
- Author(s)
  Yamaji, T., Nishikawa, K., Hanada, K.
- Organizer
  The 28^<th> Naito Conference on Glycan Expression and Regulation [I]
- Place of Presentation
  湘南国際村センター(神奈川県)
- Year and Date
  2010-07-29
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010
- Author(s)
  Yamaji, T., Nishikawa, K., Hanada, K.
- Organizer
  The 28^<th> Naito Conference on Glycan Expression and Regulation[I]
- Place of Presentation
  湘南
- Year and Date
  2010-07-29
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010
- Author(s)
  Yamaji T, Nishikawa T, and Hanada K
- Organizer
  The 27th Naito Conference on Membrane Dynamics and Lipid Biology [I]
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] Siglec-7を介したU937細胞の細胞死に必要な細胞外領域の同定" 日本生化学会東北支部2010
- Author(s)
  奈良清光、菅野真由美、三ツ木元章、山地俊之、山口芳樹、和栗聡、橋本康弘
- Organizer
  第76回例会・シンポジウム
- Place of Presentation
  福島
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010
- Author(s)
  Yamaji, T., Nishikawa, K., Hanada, K.
- Organizer
  The 27^<th> Naito Conference on Membrane Dynamics and Lipid Biology [I]
- Place of Presentation
  シャトレーゼガトーキンクダムサッポロ(北海道)
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Siglec-7を介したU937細胞の細胞死に必要な細胞外領域の同定2010
- Author(s)
  奈良清光、菅野真由美、三ツ木元章、山地俊之、山口芳樹、和栗聡、橋本康弘
- Organizer
  日本生化学会東北支部第76回例会・シンポジウム
- Place of Presentation
  コラッセ福島(福島県)
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010
- Author(s)
  Toshiyuki Yamaji
- Organizer
  The 27^<th> Naito Conference on Membrane Dynamics and Lipid Biology [I]
- Place of Presentation
  Sapporo, Hokkaido, Japan
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-22370054
[Presentation] 糖鎖受容体Siglec-7を解する細胞死の分子機構の解明2010
- Author(s)
  奈良清光、三ツ木元章、榎本綾子、菅野真由美、山口芳樹、二川了次、城谷圭朗、山地俊之、山田茜、和栗聡
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010
- Author(s)
  Yamaji, T., Nishikawa, K., Hanada, K.
- Organizer
  The 27^<th> Naito Conference on Membrane Dynamics and Lipid Biology [I]
- Place of Presentation
  札幌
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] 志賀毒素耐性遺伝子の単離2009
- Author(s)
  山地俊之、西川喜代孝、花田賢太郎
- Organizer
  第29回日本糖質学会年会
- Place of Presentation
  高山
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] 志賀毒素耐性遺伝子の単離2009
- Author(s)
  山地俊之、西川喜代孝、花田賢太郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Binding specificity of siglec-7 prepared from various animal cell lines2009
- Author(s)
  Ito, S., Ito, N., Tsuchida, A., Tokuda, N., Yagi, H., Kato, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Crocker, P.R., Furukawa K.
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] Binding specificity of siglec-7 prepared from various animal cell lines2008
- Author(s)
  Ito, S., Ito, N., Tsuchida, A., Tokuda, N., Yagi, H., Kato, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Crocker, P. R., and Furukawa K.
- Organizer
  日本分子生物学会年会・日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20770114
[Presentation] アフリカミドリザル腎由来Vero細胞のゲノム構造決定
- Author(s)
  花田賢太郎、山地俊之、黒田誠、関塚剛史、小原有弘、笠井文生、平山知子、長田直樹
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25670065

1. HANADA KENTARO (30192701)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
2. SAITO Kyoko (70235034)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KUMAGAI Keigo (40443105)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. SUGIKI Toshihiko (70635698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUKASAWA Masayoshi (20291130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKUMA Chisato (80782888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Ishii Yoshiyuki (90342899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 関塚剛史 (40462775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 谷田以誠 (30296868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 本間悠太 (70812642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAKUMA Keiichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. OSADA Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 神奈木玲児

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 黒川量雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 齋藤恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaji Toshiyuki 山地 俊之

YAMAJI Toshiyuki 山地 俊之

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CRISPR全ゲノム探索によるThogotovirus属ウイルスの宿主受容体の同定

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A replicon-based screen of yellow fever virus host factors: Toward generation of highly productive virus-producer cell lines

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Comprehensive analysis of the sphingolipid recycling pathway based on genome-wide screeningPrincipal Investigator

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Omics analysis in human papillomavirus cell entry

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Exploration of Glucosylceramide Transport Factors Using CRISPR LibraryPrincipal Investigator

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Genomics-based improvement of Vero cells for virus growth

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Search for new factors involved in glycolipid metabolism and transport by a genome-wide shRNA screenPrincipal Investigator

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Molecular strategy for the prevention of Chlamydia hijacking of a host lipid transport system

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Regulation of glycosphingolipids biosynthesis by multi-spanning transmembrane protein family TMBIMs and their molecular machineryPrincipal Investigator

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Regulatory mechanism of intracellular trafficking of ceramide

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A genetic biochemical search and analysis for factors involved in glycosphingolipid metabolism and trafficPrincipal Investigator

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[Journal Article] Construction of Sphingolipid Remodeled Cells by Genome Editing2023

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[Journal Article] Involvement of a cluster of basic amino acids in phosphorylation-dependent functional repression of the ceramide transport protein CERT2022

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Yamaji Toshiyuki 山地俊之

YAMAJI Toshiyuki 山地俊之