Murakami Tsutomu 村上努

… Alternative Names

MURAKAMI Tsutomu 村上努

Less

Researcher Number	50336385
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2022: 国立感染症研究所, エイズ研究センター, 主任研究官 2016 – 2018: 国立感染症研究所, エイズ研究センター, 室長 2014 – 2015: 国立感染症研究所, その他部局等, その他 2010 – 2012: 国立感染症研究所, エイズ研究センター, 室長 2004 – 2005: 国立感染症研究所, エイズ研究センター, 主任研究官 2002 – 2003: 琉球大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Virology / Basic Section 54030:Infectious disease medicine-related / Basic Section 49060:Virology-related / Virology Except Principal Investigator Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 58020:Hygiene and public health-related: including laboratory approach / General surgery
Keywords	Principal Investigator HIV-1 / HIV / 二量体化 / 膜融合 / カプシド蛋白質 / 抗HIV剤 / 侵入阻害剤 / I型膜融合 / 低分子 / 二量体 … More / 阻害ペプチド / 阻害剤 / host factors / cell-type dependent / matrix / uncoating / 脱穀 / 宿主因子 / 細胞依存性 / マトリックス / 脱殻 / Viral protease / Processing / Membrane fusion / entry / Virus binding / Gag proteins / Env proteins / プロテアーゼ / Gagプロセッシング / ウイルスプロテアーゼ / プロセッシング / ウイルスの吸着・侵入 / Gag蛋白 / Env蛋白 / マトリックス蛋白質 / 抗HIV-1活性 / カプシド / 抗HIV-1薬 / Gag蛋白質 / ペプチド / 粒子形成 / 細胞内輸送 / Rab蛋白質 / Rab 蛋白質 … More Except Principal Investigator リン酸化 / 活性化 / プロドラッグ / 抗HIV薬 / リン酸プロドラッグ / 阻害剤 / ポリメラーゼ / 核酸アナログ / 共有結合医薬 / 分子疫学 / 宿主側因子 / 遺伝子変異 / 病態進行 / エイズ発症 / HIV / 自然免疫 / 免疫制御 / 移植免疫 Less

カプシド蛋白質の二量体化を標的とした新規抗HIV薬開発に向けた基礎研究Principal Investigator
- Principal Investigator
  
  村上努
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  National Institute of Infectious Diseases
Molecular design strategy to avoid side effects of covalent drugs
- Principal Investigator
  
  Kimura Yasuaki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Nagoya University
Development of highly active HIV fusion inhibitorsPrincipal Investigator
- Principal Investigator
  
  Murakami Tsutomu
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
Analysis of viraal and host factors affecting the rapid disease progression of novel HIV variant infection.
- Principal Investigator
  
  Kawahata Takuya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Osaka Institute of Public Health
Transplantation tolerance by regulatory immune response through innate immunity stimulation
- Principal Investigator
  
  Fujino Masayuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Institute of Infectious Diseases
Inhibition of HIV-1 by Gag peptidesPrincipal Investigator
- Principal Investigator
  
  Murakami Tsutomu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Role of Rab proteins and related host factors in HIV-1 assemblyPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Tsutomu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Identification of host factors involved in HIV uncoatigPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Tutomu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Elucidation of HIV-1 envelope incorporation into virionsPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Tsutomu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  University of the Ryukyus

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2012 2011 2010 2005 Other

All Journal Article Presentation

[Journal Article] Low-molecular-weight Anti-HIV-1 Agents Targeting HIV-1 Capsid Proteins2023
- Author(s)
  Kobayakawa, T., M. Yokoyama, K. Tsuji, M. Fujino, M. Kurakami, T. Onishi, S. Boku, T. Ishii, Y.Miura, K. Shimohara, Y. Kishihara, N. Ohashi, O. Kotani, T. Murakami, H. Sato and H. Tamamura
- Journal Title
  
  RSC Advances
  
  Volume: 13 Issue: 3 Pages: 2156-2167
- DOI
  10.1039/d2ra06837k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08615, KAKENHI-PROJECT-22K15243
[Journal Article] Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins2021
- Author(s)
  Kobayakawa Takuya、Yokoyama Masaru、Tsuji Kohei、Fujino Masayuki、Kurakami Masaki、Boku Sayaka、Nakayama Miyuki、Kaneko Moemi、Ohashi Nami、Kotani Osamu、Murakami Tsutomu、Sato Hironori、Tamamura Hirokazu
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 2 Pages: 208-208
- DOI
  10.3390/biom11020208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] Potent leads based on CA-19L, an anti-HIV active HIV-1 capsid fragment2021
- Author(s)
  Tsuji Kohei、Wang Rongyi、Kobayakawa Takuya、Owusu Kofi Baffour-Awuah、Fujino Masayuki、Kaneko Moemi、Yamamoto Naoki、Murakami Tsutomu、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 30 Pages: 115923-115923
- DOI
  10.1016/j.bmc.2020.115923
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] Bivalent HIV-1 fusion inhibitors based on peptidomimetics2020
- Author(s)
  Kobayakawa T, Ebihara K, Tsuji K, Kawada T, Fujino M, Honda Y, Ohashi N, Murakami T, Tamamura H
- Journal Title
  
  Bioorg Med Chem.
  
  Volume: 28 Pages: 115812-115812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07158
[Journal Article] Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment2020
- Author(s)
  Tsuji Kohei、Owusu Kofi Baffour-Awuah、Kobayakawa Takuya、Wang Rongyi、Fujino Masayuki、Kaneko Moemi、Yamamoto Naoki、Murakami Tsutomu、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 11 Pages: 115488-115488
- DOI
  10.1016/j.bmc.2020.115488
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] Bivalent HIV-1 fusion inhibitors based on peptidomimetics2020
- Author(s)
  Kobayakawa Takuya、Ebihara Kento、Tsuji Kohei、Kawada Takuma、Fujino Masayuki、Honda Yuzuna、Ohashi Nami、Murakami Tsutomu、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 24 Pages: 115812-115812
- DOI
  10.1016/j.bmc.2020.115812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] Matrix mutations that alter Gag membrane binding modulate mature core formation and post-entry events.2019
- Author(s)
  Hikichi, Y., E. Takeda, M. Fujino, E. Nakayama, T. Matano, and T. Murakami
- Journal Title
  
  Virology
  
  Volume: 532 Pages: 97-107
- DOI
  10.1016/j.virol.2019.04.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07158, KAKENHI-PROJECT-18H02666, KAKENHI-PROJECT-18H03046
[Journal Article] Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands2019
- Author(s)
  3.Sakyiamah MM., Kobayakawa T., Fujino M., KonnoM., Narumi T., Tanaka T., Nomura W., Yamamoto N., Murakami T., and Tamamura H.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 2 Issue: 6 Pages: 1130-1138
- DOI
  10.1016/j.bmc.2019.02.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07158, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-15K10043, KAKENHI-PROJECT-16K01931
[Journal Article] Dimeric C34 derivatives linked through disulfide bridges as new HIV-1 fusion inhibitors.2019
- Author(s)
  Kobayakawa, T., K. Ebihara, Y. Honda, M. Fujino, W. Nomura, N. Yamamoto, T. Murakami, and H. Tamamura
- Journal Title
  
  Chembiochem.
  
  Volume: なし Issue: 16 Pages: 2101-2108
- DOI
  10.1002/cbic.201900187
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07158, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19H02827
[Journal Article] Identification of human immunodeficiency virus type-1 Gag-TSG101 interaction inhibitors by high-throughput screening2018
- Author(s)
  Lowela Siarot, Nopporn Chutiwitoonchai, Hirotaka Sato, Hao Chang, Hironori Sato, Masayuki,Fujino,Tsutomu Murakami,Toshihiro Aono, Eiichi Kodama, Kazumichi Kuroda, Masami Takei, Yoko Aida
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 503 Issue: 4 Pages: 2970-2976
- DOI
  10.1016/j.bbrc.2018.08.079
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02590, KAKENHI-PROJECT-16H05346, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-15K10043
[Journal Article] Identification of human immunodeficiency virus type-1 Gag-TSG101 interaction inhibitors by high-throughput screening.2018
- Author(s)
  2.Siarot L., Chutiwitoonchai N., Sato H., Chang H., Sato H., Fujino M,. Murakami T., Aono T, Kodama E., Kuroda K., Takei M., Aida Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 503 Pages: 2970-2976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07158
[Journal Article] Development of Anti-HIV Peptides Based on a Viral Capsid Protein2017
- Author(s)
  Takaaki Mizuguchi, Nami Ohashi, Daichi Matsumoto, Chie Hashimoto, Wataru Nomura, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura
- Journal Title
  
  Biopolymers: Peptide Science
  
  Volume: 印刷中 Issue: 1
- DOI
  10.1002/bip.22920
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-26460566, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K15139, KAKENHI-PROJECT-18K07158
[Journal Article] Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins2015
- Author(s)
  Mizuguchi T, Ohashi N, Nomura W, Komoriya M, Hashimoto C, Yamamoto N, Murakami T, and Tamamura H
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Pages: 4423-4427
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460566
[Journal Article] HIV感染症の治癒を目指して2015
- Author(s)
  村上　努
- Journal Title
  
  日本エイズ学会誌
  
  Volume: 17
- NAID
  40020506362
- Data Source
  KAKENHI-PROJECT-26460566
[Journal Article] The Interaction of HIV -1 with the Host Factors2005
- Author(s)
  Jun Komzno, Yuko Futahasi, Emiko Urano, Kosuke Miyauchi, Tsutomu Murakami, Zene Matsuda, Naoki Yamamoto
- Journal Title
  
  Jpn.J.Infect.Dis 58(3)
  
  Pages: 125-130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590389
[Journal Article] The Interaction of HIV-1 with the Host Factors2005
- Author(s)
  Komano J, Futahasi Y, Urano E, Miyauti K, Murakami T, Matuda Z, Yamamoto N
- Journal Title
  
  Jpn J Infect Dis 58巻3号
  
  Pages: 125-130
- Data Source
  KAKENHI-PROJECT-16590389
[Journal Article] The Interaction of HIV-1 with the Host Factors.2005
- Author(s)
  Jun Komano, Yuuko Futahasi, Emiko Urano, Kosuke Miyauti, Tsutomu Murakami, Zen Matuda, Naoki Yamamoto.
- Journal Title
  
  Jpn J Infect Dis. 58巻3号
  
  Pages: 125-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590389
[Journal Article] AIDSの新たな治療標的を求めて2005
- Author(s)
  山本直樹, 松田善衛, 村上努, 駒野淳
- Journal Title
  
  HIV-1の宿主因子.実験医学 23巻13号
  
  Pages: 8719-8728
- Data Source
  KAKENHI-PROJECT-16590389
[Journal Article] AIDSの新たな治療標的を求めて : HIV-1の宿主因子.2005
- Author(s)
  山本直樹, 松田善衛, 村上努, 駒野淳
- Journal Title
  
  実験医学 23巻13号
  
  Pages: 8719-8728
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590389
[Journal Article] Toward a discovery of novel targets for AIDS treatment : host factors for HIV2005
- Author(s)
  Naoki Yamamoto, Zen Matsuda, Tsutomu Murakami, Jun Komano
- Journal Title
  
  Jikkenigaku 23(13)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590389
[Presentation] Gag蛋白質前駆体（Pr55Gag）の折畳み制御機構の予測と検証2022
- Author(s)
  村上　努、横山　勝、佐藤裕徳、野間口雅子、小谷　治
- Organizer
  第36回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K08615
[Presentation] カプシド二量体化を標的とした新規抗HIV-1低分子化合物の解析2020
- Author(s)
  村上　努、小早川拓也、倉上真樹、横山　勝、小谷　治、辻　耕平、佐藤裕徳、玉村啓和
- Organizer
  第34回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] 二量体化HIV-1膜融合阻害剤の作用機序2019
- Author(s)
  村上　努、海老原健人、小早川拓也、藤野真之、児玉栄一、玉村啓和
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] プロテアーゼ領域と逆転写酵素領域の配列を用いた新型変異HIV 感染のスクリーニング法に関する検討2019
- Author(s)
  渡邊大、川畑拓也、森治代、小島洋子、駒野淳、塩田達雄、中山英美、村上努、桝田智仁、廣田和之、上地隆史、西田恭治、上平朝子、白阪琢磨
- Organizer
  第33回近畿エイズ研究会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] 二量体化HIV-1膜融合阻害薬の作用機構2019
- Author(s)
  村上　努、海老原健人、小早川拓也、藤野真之、児玉栄一、玉村啓和
- Organizer
  第33回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] 二量体化HIV-1膜融合阻害薬の作用機構2019
- Author(s)
  村上　努、海老原健人、小早川拓也、藤野真之、児玉栄一、玉村啓和
- Organizer
  第33回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] 二量体化HIV-1膜融合阻害剤の作用機序2019
- Author(s)
  村上　努、海老原健人、小早川拓也、藤野真之、児玉栄一、玉村啓和
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] HIV陽性患者の中枢神経病変 -脳生検術の必要性-2019
- Author(s)
  高野浩司、西本渓佑、山﨑弘輝、村上皓紀、館　哲郎、木谷知樹、金村米博、中島伸、桝田智仁、来住知美、廣田和之、上地隆史、渡邊　大、西田恭治、上平朝子、藤中俊之
- Organizer
  日本脳神経外科学会第78回学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] 二量体化に基づいた新規抗HIV-1膜融合阻害薬の創出2018
- Author(s)
  村上　努、海老原健人、藤野真之、本田柚奈、小早川拓也、野村　渉、玉村啓和
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10043
[Presentation] ウイルスポリメラーゼの不可逆的阻害を目指した新規2’-&βセレノ核酸アナログ.2018
- Author(s)
  村上　努、木村康明、新美結士、藤野真之、片倉秀雄、鈴木哲朗、児玉栄一、阿部　洋.
- Organizer
  第32回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Biological and molecular characterization of a novel anti-HIV-1 compound created by in silico design and de novo organic synthesis2018
- Author(s)
  Murakami T, Fujino M, Yokoyama M, Kobayakawa T, Takeuchi H, Masuda T, Kotani O, Tamamura H, Sato H.
- Organizer
  The 2018 Meeting on Retroviruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10043
[Presentation] Characterization of novel HIV-1 inhibitors targeting Gag-TSG101 interaction2018
- Author(s)
  Siarot Lowela、Chutiwitoonchai Nopporn、佐藤洋隆、Chang Hao、小谷治、横山勝、佐藤裕徳、藤野真之、村上勉、近藤恭光、本田香り、長田裕之、上田一樹、伊藤嘉浩、青野俊裕、児玉栄一、黒田和道、武井正美、間陽子
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10043
[Presentation] ウイルスポリメラーゼの不可逆阻害を目指した新規2'-& βセレノ核酸アナログの創製2018
- Author(s)
  村上　努、木村康明、新美結士、藤野真之、片倉秀雄、鈴木哲朗、児玉栄一、阿部　洋
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] Development of new membrane fusion inhibitors against HIV-1 by “dimerization” strategy2018
- Author(s)
  Murakami T, X Ebihara K, Fujino M, Honda Y, Kobayakawa T, Nomura W, Tamamura H
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10043
[Presentation] Development of 2’-β Seleno nucleoside analogs as irreversible inhibitors for viral polymerases.2018
- Author(s)
  Kimura Y, Niimi Y, Katakura H, Suzuki T, Murakami, T, Kodama E, Abe H.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Characterization of novel HIV-1 inhibitors targeting Gag-TSG101 interaction2018
- Author(s)
  L. Siarot、N. Chutiwitoonchai、佐藤洋隆、H. Chang、小谷　治、横山　勝、佐藤裕徳、藤野真之、村上　努、近藤恭光、本田香織、長田裕之、上田一樹、伊藤嘉浩、青野俊裕、児玉栄一、黒田和道、武井正美、間　陽子
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] Characterization of Novel HIV-1 inhibitors targeting Gag-TSG101 interaction.2018
- Author(s)
  L. Siarot、N. Chutiwitoonchai、佐藤洋隆、H. Chang、小谷　治、横山　勝、佐藤裕徳、藤野真之、村上　努、近藤恭光、本田香織、長田裕之、上田一樹、伊藤嘉浩、青野俊裕、児玉栄一、黒田和道、武井正美、間　陽子.
- Organizer
  第32回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Development of 2’-β modified nucleosides for irreversible viral polymerases inhibitor.2018
- Author(s)
  Niimi Y, Katakura H, Suzuki T, Takeda A, Murakami T, Kodama E, Abe H.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Development of new membrane fusion inhibitors against HIV-1 by dimerization strategy.2018
- Author(s)
  Murakami T, Ebihara K, Fujino M, Honda Y, Kobayakawa T, Nomura W, Tamamura H. Development of new membrane fusion inhibitors against HIV-1 by dimerization strategy.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Biological and molecular characterization of a novel anti-HIV-1 compound created by in silico design and de novo organic synthesis.2018
- Author(s)
  Murakami T, Fujino M, Yokoyama M, Kobayakawa T, Takeuchi H, Masuda T, Kotani O, Tamamura H, Sato H.
- Organizer
  Cold Spring Harbor Laboratory 43rd annual meeting on Retroviruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Development of 2’-β Seleno nucleoside analogs as irreversible inhibitors for viral polymerases2018
- Author(s)
  Kimura Y, Niimi Y, Katakura H, Suzuki T, Murakami, T, Kodama E, Abe H
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] Biological and molecular characterization of a novel anti-HIV-1 compound created by in silico design and de novo organic synthesis2018
- Author(s)
  Murakami T, Fujino M, Yokoyama M, Kobayakawa T, Takeuchi H, Masuda T, Kotani O, Tamamura H, Sato H
- Organizer
  Cold Spring Harbor Laboratory 43rd annual meeting on Retroviruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] ウイルスポリメラーゼの不可逆阻害を目指した新規2'-&βセレノ核酸アナログの創製2018
- Author(s)
  村上　努、木村康明、新美結士、藤野真之、片倉秀雄、鈴木哲朗、児玉栄一、阿部　洋
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10043
[Presentation] Development of new membrane fusion inhibitors against HIV-1 by dimerization strategy2018
- Author(s)
  Murakami T, Ebihara K, Fujino M, Honda Y, Kobayakawa T, Nomura W, Tamamura H
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] Development of 2’-β modified nucleosides for irreversible viral polymerases inhibitor2018
- Author(s)
  Niimi Y, Katakura H, Suzuki T, Takeda A, Murakami T, Kodama E, Abe H
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03046
[Presentation] 二量体化に基づいた新規膜融合阻害剤の創出.2018
- Author(s)
  村上　努、海老原健人、藤野真之、本田柚子奈、小早川拓也、野村　渉、玉村啓和.
- Organizer
  第32回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Design and virological evaluation of partial peptides of HIV-1 capsid2017
- Author(s)
  Tsutomu Murakami, Moemi Kaneko, Masayuki Fujino, Wataru Nomura, Hirokazu Tamamura
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10043
[Presentation] HIV外皮タンパク質gp41由来ペプチドC34を基にした二価型膜融合阻害剤の創製2017
- Author(s)
  海老原健人, 本田柚子奈, 水口貴章, 野村　渉, 藤野真之, 村上　努, 玉村啓和
- Organizer
  第27回抗ウイルス療法学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10043
[Presentation] NanoBRET法を用いた生細胞内HIV-1 Gagの多量体化解析および結合宿主因子探索.2016
- Author(s)
  宮川　敬、松山慎一郎、村上　努、梁　明秀
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-26460566
[Presentation] 複製前期過程に障害を有するHIV-1マトリックス(MA)変異体のウイルス学的解析2016
- Author(s)
  引地優太、武田英里、藤野真之、Eric O. Freed、中山英美、村上　努
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-26460566
[Presentation] HIV-1カプシドタンパク質由来ペプチドライブラリーの構築と阻害剤の創出2015
- Author(s)
  谷田部夏香、松本大地、橋本知恵、藤野真之、水口貴章、大橋南美、野村　渉、村上　努、玉村啓和
- Organizer
  第29回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Year and Date
  2015-11-29
- Data Source
  KAKENHI-PROJECT-26460566
[Presentation] R Functional analysis of Rab11a in HIV-1 assembly.2012
- Author(s)
  Murakami T., H. Wu, M. Kawamata, J. Chiba, and T. Takemura
- Organizer
  The 2012 Meeting on Retroviruses
- Place of Presentation
  Cold Spring Harbor, USA
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Functional analysis of Rab11a in HIV-1 assembly.2012
- Author(s)
  村上　努
- Organizer
  2012 Meeting on Retroviruses
- Place of Presentation
  Cold Spring Harbor, USA
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Role of Rab11a in Virus Assembly of HIV-12011
- Author(s)
  Murakami T., H.Wu, M.Kawamata, J.Chiba, T.Takemura
- Organizer
  XV International Congress of Virology
- Place of Presentation
  Sapporo convention Center, Sapporo
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Functional analysis of Rab 11a in HIV-1 Replication2011
- Author(s)
  Murakami T., H.Wu, M.Kawamata, K.Hayashi, J.Chiba, T.Takemura
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Role of Rab11a in HIV-1 assembly2011
- Author(s)
  Murakami T., H. Wu, M.Kawamata, J.Chiba, T.Takemura
- Organizer
  The 2011 Meeting on Retroviruses
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Role of Rab11a in Virus Assembly of HIV-1.2011
- Author(s)
  Murakami T., H. Wu, M. Kawamata, J. Chiba, and T. Takemera
- Organizer
  XV International Congress of Virology
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Role of Rab11a in HIV-1 assembly2011
- Author(s)
  Murakami T., H. Wu, M. Kawamata, J. Chiba, and T. Takemura
- Organizer
  The 2011 Meeting on Retroviruses
- Place of Presentation
  Cold Spring Harbor, USA,
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] HIV-1 粒子形成過程におけるRab11a 蛋白質の機能解析2011
- Author(s)
  呉鴻規、竹村太地郎、川又美弥子、千葉丈、村上努
- Organizer
  第25回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Roles of Rab proteins in HIV-1 assembly2010
- Author(s)
  T.Murakami, H.Wu, M.Kawamata, M.Tsuruoka, J.Chiba, T.Takemura.
- Organizer
  The 10^<th> Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] Rab蛋白質のHIV-1複製における役割2010
- Author(s)
  村上努、呉鴻規、川又美弥子、鶴岡幹大、千葉丈、竹村太地郎
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590427
[Presentation] HIV-1外被タンパク質gp41-CHRの二量体構造を基盤とした膜融合阻害剤の有用性
- Author(s)
  野村　渉、水口　貴章、大橋　南美、Mathieu Metifiot、藤野　真之、Yves Pommier、駒野　淳、村上　努、玉村　啓和
- Organizer
  第28回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26460566
[Presentation] HIV-1マトリックス(MA)変異体を用いた複製前期過程の解析
- Author(s)
  引地　優太、武田　英里、藤野　真之、Eric O. Freed、中山　英美、塩田　達雄、俣野　哲朗、村上　努
- Organizer
  第28回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26460566
[Presentation] 新規 CXCR4阻害剤 KRH-3955 耐性HIV-1の誘導とその解析
- Author(s)
  引地　優太、横山　勝、竹村　太地郎、藤野　真之、熊倉　成、山本　直樹、佐藤　祐徳、俣野　哲朗、村上　努
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26460566

1. 玉村啓和 (80217182)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. YOSHIDA Atsushi (10242778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TANAKA Yuetsu (30163588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YAMAMOTO Naoki (00094053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. Fujino Masayuki (50392329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. Kawahata Takuya (80270768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Kimura Yasuaki (80769977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 森一泰 (20270655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 梨井康 (60321890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 塩田達雄 (00187329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 渡邊大 (10372624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 森治代 (20250300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 駒野淳 (60356251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 小島洋子 (70291218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. NOMURA Wataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. Sato Hirotaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 間陽子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murakami Tsutomu 村上 努

MURAKAMI Tsutomu 村上 努

Research Projects

Research Products

Co-Researchers

カプシド蛋白質の二量体化を標的とした新規抗HIV薬開発に向けた基礎研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular design strategy to avoid side effects of covalent drugs

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of highly active HIV fusion inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of viraal and host factors affecting the rapid disease progression of novel HIV variant infection.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transplantation tolerance by regulatory immune response through innate immunity stimulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibition of HIV-1 by Gag peptidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Rab proteins and related host factors in HIV-1 assemblyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of host factors involved in HIV uncoatigPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of HIV-1 envelope incorporation into virionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Low-molecular-weight Anti-HIV-1 Agents Targeting HIV-1 Capsid Proteins2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potent leads based on CA-19L, an anti-HIV active HIV-1 capsid fragment2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bivalent HIV-1 fusion inhibitors based on peptidomimetics2020

Author(s)

Journal Title

Data Source

[Journal Article] Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment2020

Author(s)

Murakami Tsutomu 村上努

MURAKAMI Tsutomu 村上努