Ohtake Kazuo 大竹一男

… Alternative Names

大竹一男オオタケカズオ

OHTAKE Kazuo 大竹一男

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Researcher Number	50337482
Other IDs
Affiliation (Current)	2025: 城西大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2020: 城西大学, 薬学部, 准教授 2015 – 2016: 城西大学, 薬学部, 助教 2007 – 2012: 城西大学, 薬学部, 助教 2004 – 2005: 城西大学, 薬学部・病態解析学講座, 助手
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Applied health science / Digestive surgery / Emergency medicine
Keywords	Principal Investigator 一酸化窒素 / ERK / Raf / リン酸化 / RKIP / 生理活性 / 翻訳後修飾 / 細胞増殖 / ニトロソ化 / シグナル伝達 … More / 蛋白質 / 整理活性 / 癌 / ニトロソ化たんぱく質 / プロテオーム / 亜硝酸塩 / 硝酸塩 / ニトロソ化たん白質 / 胃粘膜 … More Except Principal Investigator 糖尿病 / 絶食 / アポトーシス / 誘導型NO合成酵素 / 一酸化窒素 / 低栄養 / BDHQ / ADAS-jcog / 長谷川式 / 改定長谷川式簡易認知スケール / 認知機能低下予防 / 認知機能 / アルツハイマー型認知症 / 改定長谷川式 / ADAS-Jcog / MMSE / HDS-R / 高齢者 / 微量栄養素 / 認知機能検査 / 軽度認知障害 / 認知症 / DHA / EPA / 血管内皮機能障害 / 低酸素トレーニング / n-3系多可不飽和脂肪酸 / 血管内皮細胞 / 脂肪酸 / 血管内皮機能 / エイコサペンタエン酸 / n-3系多価不飽和脂肪酸 / 糖尿病合併症 / 虚血再灌漑 / デキサメサゾン / 亜硝酸 / 虚血再灌流 / クラッシュ症候群 / 腸蠕動運動 / 細胞増殖 / ROS / グルタミン / nNOS / iNOS / 廃用性腸管萎縮 / 神経型NO合成酵素 / 再摂食 / 廃用性腸管粘膜萎縮 / 栄養 / -酸化窒素 / 腸管萎縮 / 腸管粘膜萎縮 Less

The effect of prophylactic supplementation of insufficient micronutrients for cognitive impairment in Japanese senile.
- Principal Investigator
  
  Kasono Keizo
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Josai University
The investigations of the effects of fatty acids consumption or direct administration on the functions of cardiovascular system.
- Principal Investigator
  
  Keizo Kasono
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Josai University
The role of neuronal and inducible NOS in the regulation of intestinal apoptosis in fasting and refeeding rat
- Principal Investigator
  
  UCHIDA Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Josai University
tudy of therapeutic effect of sodium nitrite on crush syndrome
- Principal Investigator
  
  KOBAYASHI Jun
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Josai University
Effect of nitorosylated- and phosphorylated-RKIP on cell-proliferation signal in gastric cancer cellsPrincipal Investigator
- Principal Investigator
  
  OHTAKE Kazuo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Josai University
絶食時の廃用性腸管萎縮における一酸化窒素の役割に関する研究
- Principal Investigator
  
  UCHIDA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Josai University
マウス胃液及び胃粘膜上皮細胞におけるニトロソ化たん白質の網羅的解析Principal Investigator
- Principal Investigator
  
  大竹一男
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Josai University

All 2021 2020 2019 2016 2013 2012 2011 2009

All Journal Article Presentation

[Journal Article] 高齢者に不足しがちな微量栄養素の補充による認知機能低下予防効果の検討（第2報）2021
- Author(s)
  加園恵三、糸井郁美、本松茂、柴祥子、大竹一男、加藤勇太
- Journal Title
  
  地域ケアリング
  
  Volume: 23 Pages: 60-64
- NAID
  40022635204
- Data Source
  KAKENHI-PROJECT-17K01866
[Journal Article] 高齢者に不足しがちな微量栄養素の補充による認知機能低下予防効果の検討2020
- Author(s)
  加園恵三、糸井郁美、本松茂、高村亜矢乃、柴祥子、大竹一男、加藤勇太
- Journal Title
  
  地域ケアリング
  
  Volume: 22 Pages: 67-71
- Data Source
  KAKENHI-PROJECT-17K01866
[Journal Article] 高齢者に不足しがちな微量栄養素の補充による認知機能低下予防効果の検討　～亜鉛と認知症の関連～2020
- Author(s)
  加園恵三、柴祥子、大竹一男、加藤勇太
- Journal Title
  
  細胞
  
  Volume: 52 Pages: 130-134
- NAID
  40022457178
- Data Source
  KAKENHI-PROJECT-17K01866
[Journal Article] Effects of Fish Oil Supplement on Normobaric Hypoxic Training of the University Male Ekiden Runners2016
- Author(s)
  櫛部静二、小林　悟、竹之内康広、金　賢珠、新井尚之、野部浩司、大竹一男、白幡　晶、加園恵三
- Journal Title
  
  Journal of Lipid Nutrition
  
  Volume: 25 Issue: 1 Pages: 61-74
- DOI
  10.4010/jln.25.61
- NAID
  130005151388
- ISSN
  1343-4594, 1883-2237
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26350904
[Journal Article] Acute lethal crush-injured rats can be successfully rescued by a single injection of high-dose dexamethasone through a pathway involving PI3K-Akt-eNOS signaling2013
- Author(s)
  Isamu Murata, Kazuya Ooi, Shingo Shoji, Yohei Motohashi, Miwa Kan, Kazuo Ohtake, Soichiro Kimura, Hideo Ueda, GenyaNakano,Kunihiro Sonoda, Yutaka Inoue, Hiroyuki Uchida, Ikuo Kanamoto,Yasunori Morimoto, and Jun Kobayashi
- Journal Title
  
  Journal of Trauma and Acute Care Surgery
  
  Volume: (in press)
- NAID
  120005539642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592021
[Journal Article] Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model2012
- Author(s)
  Isamu Murata, Ryo Nozaki, Kazuya Ooi,Kazuo Ohtake, Soichiro Kimura, Hideo Ueda,Genya Nakano, Kunihiro Sonoda, Yutaka Inoue, Hiroyuki Uchida, Ikuo Kanamoto,Yasunori Morimoto, Jun Kobayashi
- Journal Title
  
  Journal of Trauma
  
  Volume: Vol.72 Pages: 1548-1554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592021
[Journal Article] Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model2012
- Author(s)
  Isamu Murata, Ryo Nozaki, Kazuya Ooi, Kazuo Ohtake, Soichiro Kimura, Hideo Ueda, Genya Nakano, Kunihiro Sonoda, Yutaka Inoue, Hiroyuki Uchida, Ikuo Kanamoto, Yasunori Morimoto, Jun Kobayashi
- Journal Title
  
  Journal of Trauma
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592021
[Journal Article] Characterization of systemic and histologicinjury following crush syndrome andintervals of reperfusion in a small animal model2011
- Author(s)
  Isamu Murata, Kazuya Ooi, Hiromi Sasaki, Soichiro Kimura, Kazuo Ohtake, Hideo Ueda, Hiroyuki Uchida, Norikiyo Yasui,Yasuhiro Tsutsui, Naoya Yoshizawa, Ichiro Hirotsu, Yasunori Morimoto, Jun Kobayashi
- Journal Title
  
  Journal of Trauma
  
  Volume: Vol. 70 Pages: 1453-1463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592021
[Journal Article] Characterization of systemic and histologic injury following crush syndrome and intervals of reperfusion in a small animal model2011
- Author(s)
  Isamu Murata, Kazuya Ooi, Hiromi Sasaki, Soichiro Kimura, Kazuo Ohtake, Hideo Ueda, Hiroyuki Uchida, Norikiyo Yasui, Yasuhiro Tsutsui, Naoya Yoshizawa, Ichiro Hirotsu, Yasunori Morimoto, Jun Kobayashi
- Journal Title
  
  Journal of Trauma
  
  Volume: 70 Pages: 1453-1463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592021
[Journal Article] Proteomic approach for identification of protein S-nitrosation in mousegastric mucosa treated with S-nitrosoglutathione2009
- Author(s)
  K.Ohtake, 他3名
- Journal Title
  
  J Proteomics 72
  
  Pages: 750-760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790505
[Journal Article] Proteomic approach for identification of protein S-nitrosation in mouse gastric mucosa2009
- Author(s)
  Ohtake K, Shimada N, Uchida N, Kobayashi
- Journal Title
  
  Nitric Oxide 20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790505
[Journal Article] Proteomic approach for identification of protein S-nitrosation in mouse gastric mucosa treated with S-nitrosoglutathione2009
- Author(s)
  Ohtake K, Shimada N, Uchida N, Kobayashi
- Journal Title
  
  J. Proteomics 72
  
  Pages: 750-760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790505
[Journal Article] Proteomic approach for identification of protein S-nitrosation in mousegastric mucosa2009
- Author(s)
  K.Ohtake, 他3名
- Journal Title
  
  Nitric Oxide 20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790505
[Presentation] 3種類の認知機能検査を用いた糖尿病患者中心の内科外来診療における認知機能低下早期発見の試み2019
- Author(s)
  糸井　郁美、加藤　勇太、斎藤　雅文、高村　亜矢乃、大竹　一男、本松　茂、加園　恵三
- Organizer
  第62回日本糖尿病学会年次集会
- Data Source
  KAKENHI-PROJECT-17K01866
[Presentation] Crush syndromeに対する筋肉内Dexamethazone 投与の効果に関する研究2013
- Author(s)
  後藤麻依、村田勇、大竹一男、井上裕、小林順、金本郁男
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22592021
[Presentation] Crush syndrome ラットモデルに対する亜硝酸塩と輸液大量投与の相乗効果に関する研究2013
- Author(s)
  鈴木隆太、村田勇、大竹一男、井上裕、小林順、金本郁男
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22592021
[Presentation] Nitrite ameliorates ischemia/reperfusion injury of skeletal muscle in rat crush injury model2011
- Author(s)
  Jun Kobayashi, Ryo Nozaki, Isamu Murata, Kazuo Ohtake, Kazuya Ooi, Kunihiro Sonoda, Genya Nakano, Soichiro Kimura, Hideo Ueda, Hiroyuki Uchida, Yasunori Morimoto
- Organizer
  Approaching the Clinic: Nitrite and Nitrate Pathophysiology and Therapy Conference
- Place of Presentation
  アトランタ米国
- Data Source
  KAKENHI-PROJECT-22592021
[Presentation] Nitrite ameliorates ischemia/reperfusion injury of skeletal muscle in rat crush injury model2011
- Author(s)
  Jim Kobayashi, Ryo Nozaki, Isamu Murata, Kazuo Ohtake, Kazuya Ooi, Kunihiro Sonoda, Genya Nakano, Soichiro Kimura, Hideo Ueda, Hiroyuki Uchida, Yasunori Morimoto
- Organizer
  Fourth Bi-annual conference. Approaching the clinic : Nitrite and Nitrate Pathophysiology and Therapy
- Place of Presentation
  Emory Conference Center Hotel, Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-22592021
[Presentation] Proteomic approach for identification of protein S-nitrosation in mouse gastric mucosa2009
- Author(s)
  K Ohtake, 他3名
- Organizer
  THIRD INTERNATIONAL MEETING ON THE ROLE OF NITRITE IN PHYSIOLOGY, PATHOPHYSIOLOGY, AND THERAPERUTICS
- Place of Presentation
  スウェーデンストックホルムカロリンスカ研究所
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20790505
[Presentation] Proteomic approach for identification of protein S-nitrosationin mouse gastric mucosa2009
- Author(s)
  K Ohtake, 他3名
- Organizer
  THIRD INTERNATIONAL MEETING ONTHE ROLE OF NITRITE IN PHYSIOLOGY, PATHOPHYSIOLOGY, AND THERAPERUTICS
- Place of Presentation
  スウェーデンストックホルムカロリンスカ研究所
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20790505
[Presentation] S-ニトロソ化RKIPはRKIPリン酸化を阻害し、 ERI(リン酸化を活性化する2009
- Author(s)
  大竹一男, 他3名
- Organizer
  第9回日本NO学会学術集会
- Place of Presentation
  静岡グランシップ
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20790505
[Presentation] S-ニトロソ化RKIPはRKIPリン酸化を阻害し、ERKリン酸化を活性化する2009
- Author(s)
  大竹一男, 他3名
- Organizer
  第9回日本NO学会学術集会
- Place of Presentation
  静岡グランシップ
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20790505
[Presentation] ヒト胃細胞におけるNOストレスはRKIP非依存的にERKをリン酸化する2009
- Author(s)
  大竹一男
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20790505

1. Keizo Kasono (90177387)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. UCHIDA Hiroyuki (20245195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KOBAYASHI Jun (20153611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 竹之内康広 (30582233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MURATA Isamu (80610667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. 伊東順太 (40609096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 野部浩司 (30276612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 加藤勇太 (20792170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Ohtake Kazuo 大竹 一男

大竹 一男 オオタケ カズオ

OHTAKE Kazuo 大竹 一男

Research Projects

Research Products

Co-Researchers

The effect of prophylactic supplementation of insufficient micronutrients for cognitive impairment in Japanese senile.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigations of the effects of fatty acids consumption or direct administration on the functions of cardiovascular system.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of neuronal and inducible NOS in the regulation of intestinal apoptosis in fasting and refeeding rat

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

tudy of therapeutic effect of sodium nitrite on crush syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of nitorosylated- and phosphorylated-RKIP on cell-proliferation signal in gastric cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

絶食時の廃用性腸管萎縮における一酸化窒素の役割に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マウス胃液及び胃粘膜上皮細胞におけるニトロソ化たん白質の網羅的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 高齢者に不足しがちな微量栄養素の補充による認知機能低下予防効果の検討（第2報）2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 高齢者に不足しがちな微量栄養素の補充による認知機能低下予防効果の検討2020

Author(s)

Journal Title

Data Source

[Journal Article] 高齢者に不足しがちな微量栄養素の補充による認知機能低下予防効果の検討 ～亜鉛と認知症の関連～2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effects of Fish Oil Supplement on Normobaric Hypoxic Training of the University Male Ekiden Runners2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Acute lethal crush-injured rats can be successfully rescued by a single injection of high-dose dexamethasone through a pathway involving PI3K-Akt-eNOS signaling2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model2012

Author(s)

Journal Title

Data Source

[Journal Article] Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model2012

Ohtake Kazuo 大竹一男

大竹一男オオタケカズオ

OHTAKE Kazuo 大竹一男

[Journal Article] 高齢者に不足しがちな微量栄養素の補充による認知機能低下予防効果の検討　～亜鉛と認知症の関連～2020