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Iwawaki Takao  岩脇 隆夫

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IWAWAKI Takao  岩脇 隆夫

岩脇 隆夫  イワワキ タカオ

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Researcher Number 50342754
Other IDs
Affiliation (Current) 2025: 金沢医科大学, 総合医学研究所, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 金沢医科大学, 総合医学研究所, 教授
2016: 金沢医科大学, 総合医学研究所, 教授
2015: 群馬大学, 医学(系)研究科(研究院), 講師
2011 – 2014: 群馬大学, 先端科学研究指導者育成ユニット, 講師
2010: The Institute of Physical and Chemical Research, 中野生体膜研究室, 客員主管研究員 … More
2009: The Institute of Physical and Chemical Research, 岩脇独立主幹研究ユニット, ユニットリーダー(独立主幹研究員)
2003: 理研, 研究員
2002: 理化学研究所, 細胞修復機構研究チーム, 基礎科学特別研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 59020:Sports sciences-related / Biological Sciences / General physiology / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 42040:Laboratory animal science-related / Environmental physiology(including physical medicine and nutritional physiology) / Neurochemistry/Neuropharmacology
Except Principal Investigator
Basic Section 49060:Virology-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords
Principal Investigator
小胞体ストレス / 細胞ストレス / 炎症 / タンパク質品質管理 / ストレス / 運動 / 睡眠 / 疲労 / 生体イメージング / IRE1 … More / 疾患 / 老化 / マウスモデル / ミトコンドリア / 老化モデル / 疾患モデル / 過食 / エリスロポエチン / ATF4 / ムチン / 癌 / 炎症性腸疾患 / ガン / 脂質代謝 / 酸化ストレス / 天然変性タンパク質 / 分子シャペロン / PERK / IRE1 / 異常タンパク質 / RNase / 小胞体シャペロン / 妊娠 / RNA / 動脈硬化 / 抗体産生 / インスリン / 小胞体ストレス応答 / 唾液腺 / 糖尿病 / 膵臓 / 胎盤 / 血管新生 / トランスジェニックマウス / XBP1 / GFP … More
Except Principal Investigator
毛周期 / 間質性腎炎 / 腎糸球体 / 小胞体ストレス応答 / 急性肝細胞壊死 / エピゲノム / 母体免疫亢進 / 感染 / 虐待 / 育児放棄 / 脳 / マウス / 小胞体ストレス Less
  • Research Projects

    (12 results)
  • Research Products

    (162 results)
  • Co-Researchers

    (25 People)
  •  Functional analysis of endoplasmic reticulum stress disorders in the brain with a view to therapeutic interventions for inappropriate parenting

    • Principal Investigator
      田中 貴士
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kumamoto Health Science University
  •  疲労時に活性化する細胞ストレス応答の生体保護的な役割を解明するためにPrincipal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kanazawa Medical University
  •  Mechanisms of Acute Hepatocellular Necrosis Caused by Prenatal Exposure to Maternal Inflammation

    • Principal Investigator
      八田 稔久
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Kanazawa Medical University
  •  ミトコンドリアで生じる早期の機能的ストレスを可視化するモデルマウス開発Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kanazawa Medical University
  •  Molecular Cell Biology of Fatigue Mechanisms Approached from Developmental Studies of Cellular Stress and InflammationPrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kanazawa Medical University
  •  Transgenic mice for imaging of cellular stress associated with diseases and agingPrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Kanazawa Medical University
  •  Molecular mechanism of overeating regulated by cellular stress responsePrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Kanazawa Medical University
      Gunma University
  •  異常タンパク質インターフェイスとしての天然変性領域の機能解析Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  Physiological and Pathological Function of Cellular Stress ResponsesPrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Gunma University
  •  「天然」変性タンパク質による「非天然」変性タンパク質の感知・認識機構の解析Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
      The Institute of Physical and Chemical Research
  •  Identification of novel ER stress responsive pathways that function in intercellular interactionPrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General physiology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  小胞体ストレス細胞死における分子制御機構の解明Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      The Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent Other

  • [Journal Article] Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Airway Neutrophilia2024

    • Author(s)
      Wu Dandan、Zhang Xing、Zimmerly Kourtney M.、Wang Ruoning、Livingston Amanda、Iwawaki Takao、Kumar Ashok、Wu Xiang、Campen Matthew、Mandell Michael A.、Liu Meilian、Yang Xuexian O.
    • Journal Title

      American Journal of Respiratory Cell and Molecular Biology

      Volume: - Issue: 2 Pages: 169-181

    • DOI

      10.1165/rcmb.2023-0424oc

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27421
  • [Journal Article] A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages2024

    • Author(s)
      I. Sasaki, Y. Fukuda-Ohta, C. Nakai, N. Wakaki-Nishiyama, C. Okamoto, D. Okuzaki, S. Morita, S. Kaji, Y. Furuta, H. Hemmi, T. Kato, A. Yamamoto, E. Tosuji, SI Saitoh, T. Tanaka, K. Hoshino, S. Fukuda, K. Miyake, E. Kuroda, KJ Ishii, T. Iwawaki, K. Furukawa, T. Kaisho.
    • Journal Title

      Cell Reports

      Volume: 43 Issue: 4 Pages: 113981-113981

    • DOI

      10.1016/j.celrep.2024.113981

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PROJECT-23K19487, KAKENHI-PROJECT-22K07006, KAKENHI-PROJECT-22K19424, KAKENHI-PLANNED-22H05184, KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-21H04800, KAKENHI-PROJECT-23K27421
  • [Journal Article] Keratinocyte-Specific SOX2 Overexpression Suppressed Pressure Ulcer Formation after Cutaneous Ischemia?Reperfusion Injury via?Enhancement of Amphiregulin Production2024

    • Author(s)
      Inoue Yuta、Uchiyama Akihiko、Amalia Syahla Nisaa、Ishikawa Mai、Kosaka Keiji、Sekiguchi Akiko、Ogino Sachiko、Yokoyama Yoko、Torii Ryoko、Hosoi Mari、Akai Ryoko、Iwawaki Takao、Morasso Maria I.、Motegi Sei-ichiro
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 144 Issue: 1 Pages: 142-151.e5

    • DOI

      10.1016/j.jid.2023.06.202

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27421
  • [Journal Article] Partial limitation of cellular functions and compensatory modulation of unfolded protein response pathways caused by double-knockout of ATF6α and ATF6β2024

    • Author(s)
      Akai R, Hamashima H, Saito M, Kohno K, Iwawaki T
    • Journal Title

      Cell Stress Chaperones

      Volume: 29 Issue: 1 Pages: 34-48

    • DOI

      10.1016/j.cstres.2023.11.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08219, KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-23K27421
  • [Journal Article] Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis2023

    • Author(s)
      Awasthi D, Chopra S, Cho BA, Emmanuelli A, Sandoval TA, Hwang SM, Chae CS, Salvagno C, Tan C, Vasquez-Urbina L, Fernandez Rodriguez JJ, Santagostino SF, Iwawaki T, Romero-Sandoval EA, Crespo MS, Morales DK, Iliev ID, Hohl TM, Cubillos-Ruiz JR
    • Journal Title

      J Clin Invest

      Volume: 133 Issue: 17

    • DOI

      10.1172/jci167359

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-23K27421
  • [Journal Article] Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration2023

    • Author(s)
      Massoudi D, Gorman S, Kuo YM, Iwawaki T, Oakes SA, Papa FR, Gould DB
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 64 Issue: 4 Pages: 30-30

    • DOI

      10.1167/iovs.64.4.30

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-23K27421
  • [Journal Article] Dynamic change and preventive role of stress response via Keap1-Nrf2 during renal crystal formation2023

    • Author(s)
      Ushimoto C, Sugiki S, Kunii K, Inoue S, Kuroda E, Akai R, Iwawaki T, Miyazawa K
    • Journal Title

      Free Radic Biol Med

      Volume: 207 Pages: 120-132

    • DOI

      10.1016/j.freeradbiomed.2023.07.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-23K27421
  • [Journal Article] Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity2023

    • Author(s)
      Flores-Santibanez F, Rennen S, Fernandez D, De Nolf C, Van De Velde E, Gaete Gonzalez S, Fuentes C, Moreno C, Figueroa D, Lladser A, Iwawaki T, Bono MR, Janssens S, Osorio F
    • Journal Title

      Front Immunol

      Volume: 14 Pages: 1209588-1209588

    • DOI

      10.3389/fimmu.2023.1209588

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-23K27421
  • [Journal Article] ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions2023

    • Author(s)
      Jeong H, Hong EH, Ahn JH, Cho J, Jeong JH, Kim CW, Yoon BI, Koo JH, Park YY, Yang YM, Iwawaki T, Vallance BA, Chang SY, Ko HJ
    • Journal Title

      Exp Mol Med

      Volume: 55 Issue: 2 Pages: 401-412

    • DOI

      10.1038/s12276-023-00945-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-23K27421
  • [Journal Article] The Unfolded Protein Response Sensor IRE1 Regulates Activation of In Vitro Differentiated Type 1 Conventional DCs with Viral Stimuli2023

    • Author(s)
      Medel B, Bernales JI, Lira A, Fernandez D, Iwawaki T, Vargas P, Osorio F
    • Journal Title

      Int J Mol Sci

      Volume: 24 Issue: 12 Pages: 10205-10205

    • DOI

      10.3390/ijms241210205

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-23K27421
  • [Journal Article] 疲労を考える上で関心を向けざるを得ない細胞ストレス応答の分子メカニズム2022

    • Author(s)
      黒田絵莉子, 赤井良子, 岩脇隆夫
    • Journal Title

      日本疲労学会誌

      Volume: 16 Pages: 9-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] Salmonella Exhibit Altered Cellular Localization in the Presence of HLA-B27 and Codistribute with Endo-Reticular Membrane2022

    • Author(s)
      Kriston-Vizi Janos、Lenart Izabela、Iwawaki Takao、Gould Keith、Nesbeth Darren、Powis Simon J.、Antoniou Antony N.
    • Journal Title

      Journal of Immunology Research

      Volume: 2022 Pages: 9493019-9493019

    • DOI

      10.1155/2022/9493019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] The unfolded protein response transducer IRE1α promotes reticulophagy in podocytes2022

    • Author(s)
      Navarro-Betancourt Jos? R.、Papillon Joan、Guillemette Julie、Chung Chen-Fang、Iwawaki Takao、Cybulsky Andrey V.
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

      Volume: 1868 Issue: 6 Pages: 166391-166391

    • DOI

      10.1016/j.bbadis.2022.166391

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] Targeting IRE1 endoribonuclease activity alleviates cardiovascular lesions in a murine model of Kawasaki disease vasculitis2022

    • Author(s)
      Marek-Iannucci Stefanie、Yildirim Asli D.、Hamid Syed M.、Ozdemir Asli B.、Gomez Angela C.、Kocat?rk Beg?m、Porritt Rebecca A.、Fishbein Michael C.、Iwawaki Takao、Noval Rivas Magali、Erbay Ebru、Arditi Moshe
    • Journal Title

      JCI Insight

      Volume: 7 Issue: 6

    • DOI

      10.1172/jci.insight.157203

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] Intercepting IRE1 kinase‐FMRP signaling prevents atherosclerosis progression2022

    • Author(s)
      Yildirim Zehra、Baboo Sabyasachi、Hamid Syed M、Dogan Asli E、Tufanli Ozlem、Robichaud Sabrina、Emerton Christina、Diedrich Jolene K、Vatandaslar Hasan、Nikolos Fotis、Gu Yanghong、Iwawaki Takao、Tarling Elizabeth、Ouimet Mireille、Nelson David L、Yates John R、Walter Peter、Erbay Ebru
    • Journal Title

      EMBO Molecular Medicine

      Volume: 14 Issue: 4

    • DOI

      10.15252/emmm.202115344

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] Mechanisms of liver injury in high fat sugar diet fed mice that lack hepatocyte X-box binding protein 12022

    • Author(s)
      Liu Xiaoying、Taylor Sarah A.、Gromer Kyle D.、Zhang Danny、Hubchak Susan C.、LeCuyer Brian E.、Iwawaki Takao、Shi Zengdun、Rockey Don C.、Green Richard M.
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 1 Pages: e0261789-e0261789

    • DOI

      10.1371/journal.pone.0261789

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] Alterations in UPR Signaling by Methylmercury Trigger Neuronal Cell Death in the Mouse Brain2022

    • Author(s)
      Nomura Ryosuke、Takasugi Nobumasa、Hiraoka Hideki、Iijima Yuta、Iwawaki Takao、Kumagai Yoshito、Fujimura Masatake、Uehara Takashi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 23 Pages: 15412-15412

    • DOI

      10.3390/ijms232315412

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-20K07014
  • [Journal Article] Inhibition of skin fibrosis in systemic sclerosis by botulinum toxin B via the suppression of oxidative stress2021

    • Author(s)
      Baral H, Sekiguchi A, Uchiyama A, Nisaa Amalia S, Yamazaki S, Inoue Y, Yokoyama Y, Ogino S, Torii R, Hosoi M, Akai R, Iwawaki T, Ishikawa O, Motegi SI
    • Journal Title

      J Dermatol Sci

      Volume: 48 Issue: 7 Pages: 1052-1061

    • DOI

      10.1111/1346-8138.15888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism2021

    • Author(s)
      Roy A, Tomaz da Silva M, Bhat R, Bohnert KR, Iwawaki T, Kumar A
    • Journal Title

      Elife

      Volume: 10

    • DOI

      10.7554/elife.73215

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α2021

    • Author(s)
      Duwaerts CC, Siao K, Soon RK Jr, Her C, Iwawaki T, Kohno K, Mattis AN, Maher JJ
    • Journal Title

      Cell Death Differ

      Volume: 28 Issue: 5 Pages: 1455-1465

    • DOI

      10.1038/s41418-020-00671-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Journal Article] Spatiotemporal analysis of the UPR transition induced by methylmercury in the mouse brain.2021

    • Author(s)
      Hiraoka, H., Nomura, R., Takasugi, N., Akai, R., Iwawaki, T., Kumagai, Y., Fujimura, M., and Uehara, T.
    • Journal Title

      Arch. Toxicol.

      Volume: 95 Issue: 4 Pages: 1241-1250

    • DOI

      10.1007/s00204-021-02982-9

    • NAID

      120007185542

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-20J11445, KAKENHI-PROJECT-19K22498, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-21H03334, KAKENHI-PROJECT-20K07014
  • [Journal Article] IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival2020

    • Author(s)
      Batista Alyssa、Rodvold Jeffrey J.、Xian Su、Searles Stephen C.、Lew Alyssa、Iwawaki Takao、Almanza Gonzalo、Waller T. Cameron、Lin Jonathan、Jepsen Kristen、Carter Hannah、Zanetti Maurizio
    • Journal Title

      PLOS Biology

      Volume: 18 Issue: 6 Pages: e3000687-e3000687

    • DOI

      10.1371/journal.pbio.3000687

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] AAV-mediated ERdj5 overexpression protects against P23H rhodopsin toxicity2020

    • Author(s)
      Aguila Monica、Bellingham James、Athanasiou Dimitra、Bevilacqua Dalila、Duran Yanai、Maswood Ryea、Parfitt David A、Iwawaki Takao、Spyrou Giannis、Smith Alexander J、Ali Robin R、Cheetham Michael E
    • Journal Title

      Human Molecular Genetics

      Volume: 29 Issue: 8 Pages: 1310-1318

    • DOI

      10.1093/hmg/ddaa049

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Transgenic mouse model exhibiting weak red fluorescence before and strong green fluorescence after Cre/loxP-mediated recombination2020

    • Author(s)
      Akai Ryoko、Saito Michiko、Kohno Kenji、Iwawaki Takao
    • Journal Title

      Experimental Animals

      Volume: 69 Issue: 3 Pages: 306-318

    • DOI

      10.1538/expanim.19-0085

    • NAID

      130007884759

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α Promotes Zika Virus Infection via XBP12020

    • Author(s)
      Kolpikova Elena P.、Tronco Ana R.、Den Hartigh Andreas B.、Jackson Konner J.、Iwawaki Takao、Fink Susan L.
    • Journal Title

      Viruses

      Volume: 12 Issue: 3 Pages: 278-278

    • DOI

      10.3390/v12030278

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Protective effect of dimethyl fumarate for the development of pressure ulcers after cutaneous ischemia‐reperfusion injury2020

    • Author(s)
      Inoue Yuta、Uchiyama Akihiko、Sekiguchi Akiko、Yamazaki Sahori、Fujiwara Chisako、Yokoyama Yoko、Ogino Sachiko、Torii Ryoko、Hosoi Mari、Akai Ryoko、Iwawaki Takao、Ishikawa Osamu、Motegi Sei‐ichiro
    • Journal Title

      Wound Repair and Regeneration

      Volume: 28 Issue: 5 Pages: 600-608

    • DOI

      10.1111/wrr.12824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions2020

    • Author(s)
      Xu Longyong、Iwawaki Takao、Chen Xi et al
    • Journal Title

      Nature Cell Biology

      Volume: 22 Issue: 10 Pages: 1162-1169

    • DOI

      10.1038/s41556-020-00581-x

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model2020

    • Author(s)
      Yamazaki Sahori、Sekiguchi Akiko、Uchiyama Akihiko、Fujiwara Chisako、Inoue Yuta、Yokoyama Yoko、Ogino Sachiko、Torii Ryoko、Hosoi Mari、Akai Ryoko、Iwawaki Takao、Ishikawa Osamu、Motegi Sei-ichiro
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1349-1349

    • DOI

      10.1038/s41598-020-58452-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Role of IRE1α in podocyte proteostasis and mitochondrial health2020

    • Author(s)
      Navarro-Betancourt Jos? R.、Papillon Joan、Guillemette Julie、Iwawaki Takao、Chung Chen-Fang、Cybulsky Andrey V.
    • Journal Title

      Cell Death Discovery

      Volume: 6 Issue: 1 Pages: 128-128

    • DOI

      10.1038/s41420-020-00361-4

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] ERdj5 in Innate Immune Cells Is a Crucial Factor for the Mucosal Adjuvanticity of Cholera Toxin2019

    • Author(s)
      Kim MS, Yi EJ, Kim YI, Kim SH, Jung YS, Kim SR, Iwawaki T, Ko HJ, Chang SY
    • Journal Title

      Front Immunol

      Volume: 10 Pages: 1249-1249

    • DOI

      10.3389/fimmu.2019.01249

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Zinc deficiency exacerbates pressure ulcers by increasing oxidative stress and ATP in the skin2019

    • Author(s)
      Nakamura H, Sekiguchi A, Ogawa Y, Kawamura T, Akai R, Iwawaki T, Makiguchi T, Yokoo S, Ishikawa O, Motegi SI
    • Journal Title

      J Dermatol Sci

      Volume: 95 Issue: 2 Pages: 62-69

    • DOI

      10.1016/j.jdermsci.2019.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells2019

    • Author(s)
      Liu L, Zhao M, Jin X, Ney G, Yang KB, Peng F, Cao J, Iwawaki T, Del Valle J, Chen X, Li Q
    • Journal Title

      Nat Cell Biol

      Volume: 21 Issue: 3 Pages: 328-337

    • DOI

      10.1038/s41556-019-0285-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replication2019

    • Author(s)
      Antoniou AN, Lenart I, Kriston-Vizi J, Iwawaki T, Turmaine M, McHugh K, Ali S, Blake N, Bowness P, Bajaj-Elliott M, Gould K, Nesbeth D, Powis SJ
    • Journal Title

      Ann Rheum Dis

      Volume: 78 Issue: 1 Pages: 74-82

    • DOI

      10.1136/annrheumdis-2018-213532

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain2019

    • Author(s)
      Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, Kossenkov AV, Crespo MS, Dannenberg AJ, Glimcher LH, Romero-Sandoval EA, Cubillos-Ruiz JR
    • Journal Title

      Science

      Volume: 365 Issue: 6450

    • DOI

      10.1126/science.aau6499

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming2019

    • Author(s)
      Medel B, Costoya C, Fernandez D, Pereda C, Lladser A, Sauma D, Pacheco R, Iwawaki T, Salazar-Onfray F, Osorio F
    • Journal Title

      Front Immunol

      Volume: 9 Pages: 3050-3050

    • DOI

      10.3389/fimmu.2018.03050

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD2019

    • Author(s)
      Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, Iwawaki T, Ting JP, Serody JS, Murphy WJ, Hill GR, Murray PJ, Bronte V, Munn DH, Zeiser R, Blazar BR
    • Journal Title

      Blood

      Volume: 134 Issue: 19 Pages: 1670-1682

    • DOI

      10.1182/blood.2019001950

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] MITOL prevemts ER stress-induced apoptosis by IRE1 ubiquitylation at mitochondrial-ER contact sites.2019

    • Author(s)
      Takeda, K., Nagashima, S., Shiiba, I., Uda, A., Tokuyama, T., Ito, N., Fukuda, T., Matsushita, N., Ishido, S., Iwawaki, T., Uehara, T., Inatome, R., and Yanagi, S.
    • Journal Title

      EMBO J.

      Volume: 38 Issue: 15

    • DOI

      10.15252/embj.2018100999

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22498, KAKENHI-PUBLICLY-18H04869, KAKENHI-PROJECT-17H04053, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-17K08793, KAKENHI-PROJECT-19K16527
  • [Journal Article] Ablation of the Chaperone Protein ERdj5 Results in a Sjogren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients2019

    • Author(s)
      Apostolou E, Moustardas P, Iwawaki T, Tzioufas AG, Spyrou G
    • Journal Title

      Front Immunol

      Volume: 10 Pages: 506-506

    • DOI

      10.3389/fimmu.2019.00506

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap12019

    • Author(s)
      Suzuki Takafumi、Muramatsu Aki、Saito Ryota、Iso Tatsuro、Shibata Takahiro、Kuwata Keiko、Kawaguchi Shin-ichi、Iwawaki Takao、Adachi Saki、Suda Hiromi、Morita Masanobu、Uchida Koji、Baird Liam、Yamamoto Masayuki
    • Journal Title

      Cell Reports

      Volume: 28 Issue: 3 Pages: 746-758

    • DOI

      10.1016/j.celrep.2019.06.047

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H00990, KAKENHI-PROJECT-19H01019, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17H06170, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Inhibitory effect of kaempferol on skin fibrosis in systemic sclerosis by the suppression of oxidative stress2019

    • Author(s)
      Sekiguchi A, Motegi SI, Fujiwara C, Yamazaki S, Inoue Y, Uchiyama A, Akai R, Iwawaki T, Ishikawa O
    • Journal Title

      J Dermatol Sci

      Volume: 96 Issue: 1 Pages: 8-17

    • DOI

      10.1016/j.jdermsci.2019.08.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells2018

    • Author(s)
      Yuichi Tsuchiya, Michiko Saito, Hiroshi Kadokura, Jun-ichi Miyazaki, Fumi Tashiro, Yusuke Imagawa, Takao Iwawaki, Kenji Kohno
    • Journal Title

      The Journal of Cell Biology

      Volume: 217 Issue: 4 Pages: 1287-1301

    • DOI

      10.1083/jcb.201707143

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07381, KAKENHI-PROJECT-24228002, KAKENHI-PLANNED-26116006, KAKENHI-PUBLICLY-18H05047, KAKENHI-PROJECT-17H01468, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-17K15134, KAKENHI-PLANNED-26116005
  • [Journal Article] タンパク質恒常性と糖代謝異常に関わる小胞体ストレス応答の役割2018

    • Author(s)
      岩脇隆夫
    • Journal Title

      金沢医科大学雑誌

      Volume: 43 Pages: 15-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] 小胞体ストレスの生体イメージング2018

    • Author(s)
      岩脇隆夫, 赤井良子
    • Journal Title

      THE BONE

      Volume: 32 Pages: 171-177

    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response2018

    • Author(s)
      Chapple RH, Hu T, Tseng YJ, Liu L, Kitano A, Luu V, Hoegenauer KA, Iwawaki T, Li Q, Nakada D
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.31159

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A2018

    • Author(s)
      Urra H, Henriquez DR, Canovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic A, Gonzalez-Billault C, Hetz C
    • Journal Title

      Nature Cell Biology

      Volume: 20 Issue: 8 Pages: 942-953

    • DOI

      10.1038/s41556-018-0141-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress2018

    • Author(s)
      Sekiguchi A, Motegi SI, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Perera B, Nakamura H, Ogino S, Yokoyama Y, Akai R, Iwawaki T, Ishikawa O
    • Journal Title

      Journal of Dermatological Science

      Volume: 90 Issue: 2 Pages: 144-153

    • DOI

      10.1016/j.jdermsci.2018.01.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] Activation of Host IRE1α-Dependent Signaling Axis Contributes the Intracellular Parasitism of Brucella melitensis2018

    • Author(s)
      Pandey A, Lin F, Cabello AL, da Costa LF, Feng X, Feng HQ, Zhang MZ, Iwawaki T, Rice-Ficht A, Ficht TA, de Figueiredo P, Qin QM
    • Journal Title

      Frontiers in Cellular and Infection Microbiology

      Volume: 8 Pages: 103-103

    • DOI

      10.3389/fcimb.2018.00103

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine?kinase IRE1alpha2018

    • Author(s)
      Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, Tavernier S, Iwawaki T, Bloch Y, Savvides SN, Lambrecht BN, Janssens S, Elewaut D, Drennan MB
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 5340-5340

    • DOI

      10.1038/s41467-018-07758-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Correlation Between Attenuation of Protein Disulfide Isomerase Activity Through S-Mercuration and Neurotoxicity Induced by Methylmercury.2015

    • Author(s)
      Makino K, Okuda K, Sugino E, Nishiya T, Toyama T, Iwawaki T, Fujimura M, Kumagai Y, Uehara T.
    • Journal Title

      Neurotox Res

      Volume: 27 Issue: 2 Pages: 99-105

    • DOI

      10.1007/s12640-014-9494-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J03394, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25670029, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26460068
  • [Journal Article] Protection afforded by pre- or post-treatment with 4-phenylbutyrateagainst liver injury induced by acetaminophen overdose in mice2014

    • Author(s)
      Daisuke Shimizua, Yoichi Ishitsuka, Keishi Miyata, Yoshiro Tomishima, Yuki Kondo, Mitsuru Irikura, Takao Iwawaki, Yuichi Oike, Tetsumi Irie
    • Journal Title

      Pharmacol. Res.

      Volume: 87 Pages: 26-41

    • DOI

      10.1016/j.phrs.2014.06.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25461114, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
  • [Journal Article] Evaluating experimental cerebral malaria using oxidative stress indicator OKD48 mice.2014

    • Author(s)
      Imai T, Iwawaki T, Akai R, Suzue K, Hirai M, Taniguchi T, Okada H, Hisaeda H.
    • Journal Title

      Int J Parasitol.

      Volume: 44 Issue: 10 Pages: 681-685

    • DOI

      10.1016/j.ijpara.2014.06.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-25670226, KAKENHI-PROJECT-26860276, KAKENHI-PROJECT-26870094
  • [Journal Article] Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia-reperfusionin jury2014

    • Author(s)
      Toshinori Takagi, Akira Kitashoji, Takao Iwawaki, Kazuhiro Tsuruma, Masamitsu Shimazawa, Shinichi Yoshimura, Toru Iwama, Hideaki Hara
    • Journal Title

      Free Radic. Biol. Med.

      Volume: 72 Pages: 124-133

    • DOI

      10.1016/j.freeradbiomed.2014.04.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25861266
  • [Journal Article] The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control2014

    • Author(s)
      Dimitra Athanasiou, Dalila Bevilacqua, Monica Aguila, Caroline McCulley, Naheed Kanuga, Takao Iwawaki, J. Paul Chapple, Michael E. Cheetham
    • Journal Title

      Hum. Mol. Genet.

      Volume: 23 Issue: 24 Pages: 6594-6606

    • DOI

      10.1093/hmg/ddu385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] A role for regulated IRE-1 dependent decay in curtailing immunoglobulin secretion from plasma cells2014

    • Author(s)
      Sandrine Benhamron, Takao Iwawaki, Jae-Seon So, Ann-Hwee Lee, Boaz Tirosh
    • Journal Title

      Eur. J. Immunol.

      Volume: 44 Issue: 3 Pages: 867-876

    • DOI

      10.1002/eji.201343953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Inositol-requiring enzyme 1-α regulates CD8α+ dendritic cell function via regulated mRNA decay2014

    • Author(s)
      Fabiola Osorio, Simon Tavernier, Eik Hoffmann, Yvan Saeys, Liesbet Martens, Jessica Vetters, Iris Delrue, Riet De Rycke, Eef Parthoens, Philippe Poulliot, Takao Iwawaki, Sophie Janssens, Bart N. Lambrecht
    • Journal Title

      Nat. Immunol.

      Volume: 15 Issue: 3 Pages: 248-257

    • DOI

      10.1038/ni.2808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Comparative analysis of ER stress response into HIV protease inhibitors : Lopinavir but not Darunavir induces potent ER stress response via ROS/JNK pathway.2013

    • Author(s)
      Taura M, Kariya R, Kudo E, Goto H, Iwawaki T, Amano M, Suico MA, Kai H, Mitsuya H, Okada S.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 65 Pages: 778-788

    • DOI

      10.1016/j.freeradbiomed.2013.08.161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08328, KAKENHI-PROJECT-23390265, KAKENHI-PROJECT-24390049
  • [Journal Article] Paneth cells as a site of origin for intestinal inflammation2013

    • Author(s)
      Adolph,T.E.,Tomczak,M.F.,Niederreiter,L.,Ko,H.J.,Bock,J.,Martinez-Naves,E.,Glickman,J.N.,Tschurtschenthaler,M.,Hartwig,J.,Hosomi,S.,Flak,M.B.,Cusick,J.L.,Kohno,K.,Iwawaki,T.,Billmann-Born,S.,Raine,T.,Bharti,R.,Lucius,R.,Kweon,M.N.,Marciniak,S.J.,Choi,A.,Hagen,S.J.,Schreiber,S.,Rosenstiel,P.,Kaser,A.,Blumberg,RS.
    • Journal Title

      Nature

      Volume: 503 Issue: 7475 Pages: 272-276

    • DOI

      10.1038/nature12599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24390049
  • [Journal Article] 小胞体ストレスシグナルの感知・生体防御機構2013

    • Author(s)
      岩脇隆夫
    • Journal Title

      細胞

      Volume: 45 Pages: 168-171

    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] 小胞体ストレスシグナルの感知・生体防御機構2013

    • Author(s)
      岩脇 隆夫
    • Journal Title

      細胞

      Volume: 45 Pages: 168-171

    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Journal Article] 生きているマウスで酸化ストレスを見えるように2013

    • Author(s)
      及川大輔、岩脇隆夫
    • Journal Title

      化学と生物

      Volume: 51 Pages: 361-363

    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] CHOP is a critical regulator of acetaminophen-induced hepatotoxicity2013

    • Author(s)
      Dotan Uzi, Liran Barda, Viviana Scaiewicz, Maya Mills, Tobias Mueller, Agueda Gonzalez-Rodriguez, Angela M. Valverde, Takao Iwawaki, Yaakov Nahmias, Ramnik J. Xavier, Raymond T. Chung, Boaz Tirosh, Oren Shibolet
    • Journal Title

      J. Hepatol.

      Volume: 59 Issue: 3 Pages: 495-503

    • DOI

      10.1016/j.jhep.2013.04.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] ER stress transcription factor Xbp1 suppresses intestinal tumourigenesis and directs intestinal stem cells.2013

    • Author(s)
      Niederreiter, L., Fritz, T. M. J., Adolph, T.E., Krismer, A. M., Offner, F. A., Tschurtschenthaler, M., Flak, M. B., Hosomi, S., Tomczak, M. F., Kaneider, N. C., Sarcevic, E., Kempster, S. L., Raine, T., Esser, D., Rosenstiel, P., Kohno, K., Iwawaki, T., Tilg, H., Blumberg, R. S., and Kaser, A.
    • Journal Title

      J. Exp. Med.

      Volume: 210(10) Issue: 10 Pages: 2041-2056

    • DOI

      10.1084/jem.20122341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24390049
  • [Journal Article] Identification of the redox partners of ERdj5/JPDI, a PDI family member, from an animal tissue.2013

    • Author(s)
      Kadokura, H., Saito, M., Tsuru, A., Hosoda, A., Iwawaki, T., Inaba, K., & Kohno, K.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 440 Issue: 2 Pages: 245-250

    • DOI

      10.1016/j.bbrc.2013.09.063

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500496, KAKENHI-PUBLICLY-24113702, KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24580141
  • [Journal Article] MTP inhibition induces ER stress and increases gene transcription via Ire1α/cJun to enhance plasma ALT/AST.2013

    • Author(s)
      Josekutty, J., Iqbal, J., Iwawaki, T., Kohno, K., and Hussain, M.
    • Journal Title

      J. Biol. Chem.

      Volume: 288(20) Issue: 20 Pages: 14372-14383

    • DOI

      10.1074/jbc.m113.459602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24390049
  • [Journal Article] The role of the unfolded protein response in diabetes mellitus2013

    • Author(s)
      Takao Iwawaki, Daisuke Oikawa
    • Journal Title

      Semin. Immunopathol.

      Volume: 35 Issue: 3 Pages: 333-350

    • DOI

      10.1007/s00281-013-0369-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins2013

    • Author(s)
      Daisuke Oikawa, Takao Iwawaki
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 433 Issue: 4 Pages: 426-431

    • DOI

      10.1016/j.bbrc.2013.02.119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] 小胞体ストレスの可視化2012

    • Author(s)
      岩脇 隆夫
    • Journal Title

      生体の科学

      Volume: 65 Pages: 388-389

    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Journal Article] 小胞体ストレスの可視化2012

    • Author(s)
      岩脇隆夫
    • Journal Title

      生体の科学

      Volume: 65 Pages: 388-389

    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Function of yeast and amphioxus tRNA ligase in IRE1alpha-dependent XBP1 mRNA splicing2011

    • Author(s)
      Takao Iwawaki
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 413 Issue: 4 Pages: 527-531

    • DOI

      10.1016/j.bbrc.2011.08.129

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Journal Article] Positive contribution of the IRE1alpha-XBP1 pathway to placental expression of CEA family genes.2010

    • Author(s)
      Daisuke Oikawa, Ryoko Akai, Takao Iwawaki
    • Journal Title

      FEBS Lett. vol.584

      Pages: 1066-1070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Positive contribution of Erdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland.2010

    • Author(s)
      Akira Hosoda, Mio Tokuda, Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Journal Title

      Biochem. J. vol.425

      Pages: 117-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] IRE1alpha disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level.2010

    • Author(s)
      Takao Iwawaki
    • Journal Title

      PLoS ONE

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] The endoplasmic reticulum stress-CHOP pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques.2010

    • Author(s)
      Hirato Tsukano, Tomomi Gotoh, Motoyoshi Endo, Miyata Keishi, Hirokazu Tazume, Tsuyoshi Kadomatsu, Masato Yano, Takao Iwawaki, Kenji Kohno, Kimi Araki, Hiroshi Mizuta, Yuichi Oike
    • Journal Title

      Arterioscler. Thromb. Vasc.Biol. vol.30

      Pages: 1925-1932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] IRE1alpha disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level.2010

    • Author(s)
      Takao Iwawaki, Ryoko Akai, Kenji Kohno
    • Journal Title

      PLoS ONE vol.5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Identication of a consensus element recognized and cleaved by IRE1alpha.2010

    • Author(s)
      Daisuke Oikawa, Mio Tokuda, Akira Hosoda, Takao Iwawaki
    • Journal Title

      Nucleic Acid Res. vol.38

      Pages: 6265-6273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.2009

    • Author(s)
      Takao Iwawaki, Ryoko Akai, Shinya Yamanaka, Kenji Kohno
    • Journal Title

      Proc.Natl.Acad.Sci.USA vol.106

      Pages: 16657-16662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Function of IRE1 Alpha in the Placenta is Essential for Placental Development and Embryonic Viability2009

    • Author(s)
      Takao Iwawaki
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 16657-16662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Patent] 炎症レポーターシステム2014

    • Inventor(s)
      岩脇隆夫、及川大輔、石川智夫、山村研一
    • Industrial Property Rights Holder
      群馬大学、熊本大学、株式会社トランスジェニック
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-07-31
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Patent] 酸化ストレスインジケーター発現用核酸構築物とその使用2012

    • Inventor(s)
      岩脇隆夫, 及川大輔
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2012-01-20
    • Overseas
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 酸化ストレスの視点から尿路結石学と向き合う2023

    • Author(s)
      牛本千春子、國井建司郎、井上慎也、赤井良子、黒田絵莉子、岩脇隆夫、宮澤克人
    • Organizer
      日本尿路結石症学会第33回学術集会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 腎結晶形成におけるKeap1-Nrf2 経路を介したストレス応答の関与2023

    • Author(s)
      牛本千春子、杉木滋、國井建司郎、井上慎也、赤井良子、黒田絵莉子、岩脇隆夫、宮澤克人
    • Organizer
      第26回北陸泌尿器科Research Meeting
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 運動後急性腎不全の機序解明2023

    • Author(s)
      野村和利、赤井良子、谷田守、矢部友久、熊野奨、宮竹敦彦、岡田圭一郎、大串勇気、沖野一晃、藤 本圭司、倉田康孝、岩脇隆夫、横山仁、古市賢吾
    • Organizer
      第66回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 酸化ストレスの視点から尿路結石学と向き合う2023

    • Author(s)
      牛本千春子、國井建司郎、井上慎也、赤井良子、黒田絵莉子、岩脇隆夫、宮澤克人
    • Organizer
      第110回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] Deletion of IRE1α Exacerbates Diabetic Nephropathy in Mice2023

    • Author(s)
      Andrey V. Cybulsky, Joan Papillon, Julie Guillemette, Jose R. Navarro-Betancourt, Chen-Fang Chung, Takao Iwawaki, Ivan G. Fantus
    • Organizer
      KIDNEY WEEK 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] ATF6β欠損マウスが示す多動表現型と横隔膜ヘルニア2023

    • Author(s)
      赤井良子、濱嶋尚代、岩脇隆夫
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 小胞体ストレス応答のシグナル経路により制御される過食行動の分子メカニズム2022

    • Author(s)
      赤井良子、黒田絵莉子、濱嶋尚代、岩脇隆夫
    • Organizer
      第69回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] Proteostatic sensor Ire1, promotes bone formation by potentiating Wnt signaling in osteoblast progenitors2022

    • Author(s)
      Lakshmi Divya Kolora, Christian Melendez-Suchi, Sara Higsley, Veronica Butler, John Lipold, Takao Iwawaki, Maria Almeida, Kartik Shankar, Douglas J Adams, Srividhya Iyer
    • Organizer
      Gordon Research Conference (Bones and Teeth)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 腎結晶形成におけるKeap1-Nrf2経路を介したストレス応答の果たす役割2022

    • Author(s)
      牛本千春子、國井建司郎、井上慎也、赤井良子、黒田絵莉子、岩脇隆夫、宮澤克人
    • Organizer
      第16回臨床ストレス応答学会大会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] ATF6αとATF6βの二重欠損が引き起こすUPR制御機構の代償的変調と細胞機能の関係2022

    • Author(s)
      赤井良子、濱嶋尚代、斉藤美知子、河野憲二、岩脇隆夫
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 腎結晶形成におけるKeap1-Nrf2経路を介したストレス応答の関与2022

    • Author(s)
      牛本千春子、國井建司郎、井上慎也、赤井良子、黒田絵莉子、岩脇隆夫、宮澤克人
    • Organizer
      第32回日本尿路結石症学会・学術集会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] ATF6αとATF6βの二重欠損が引き起こすUPR制御機構の代償的変調と細胞機能の関係2022

    • Author(s)
      赤井良子、黒田絵莉子、濱嶋尚代、斉藤美知子、河野憲二、岩脇隆夫
    • Organizer
      第16回臨床ストレス応答学会大会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 腎結晶形成における Keap1-Nrf2経路を介した ストレス応答の解析2022

    • Author(s)
      牛本千春子、國井建司郎、井上慎也、黒田絵莉子、赤井良子、岩脇隆夫、宮澤克人
    • Organizer
      第31回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] ミトコンドリア異常を可視化するマウスの作製に向けた新規FRETレポーター遺伝子の開発2021

    • Author(s)
      黒田絵莉子、赤井良子、濱嶋尚代、岩脇隆夫
    • Organizer
      第56回金沢医科大学医学会・学術集会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 細胞ストレス応答の発展的研究から迫る疲労の分子メカニズム2021

    • Author(s)
      岩脇隆夫
    • Organizer
      第17回日本疲労学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 生体イメージングマウスを用いた腎結晶形成における酸化ストレス応答の解析2021

    • Author(s)
      牛本千春子、國井建司郎、井上慎也、赤井良子、岩脇隆夫、宮澤克人
    • Organizer
      第31回日本尿路結石症学会・学術集会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] A Non-canonical Role for IRE1α in Podocyte Endoplasmic Reticulum (ER)-phagy2021

    • Author(s)
      Jose R. Navarro-Betancourt, Joan Papillon, Julie Guillemette, Takao Iwawaki, Andrey V. Cybulsky
    • Organizer
      KIDNEY WEEK 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 赤色蛍光/発光レポーターにATF4の翻訳活性化機構を応用した統合ストレス可視化モデルマウスの開発2021

    • Author(s)
      赤井良子、黒田絵莉子、濱嶋尚代、岩脇隆夫
    • Organizer
      第68回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] The ER sensor, IRE1, promotes bone formation by increasing nuclear localization of β-catenin in osteoprogenitors2021

    • Author(s)
      Srividhya Iyer, Lakshmi Kolora, Christian Melendez-Suchi, Sara Higsley, Veronica Butler, John Lipold, Takao Iwawaki, Maria Almeida, Kartik Shankar, Douglas Adams
    • Organizer
      FASEB SRC The ER Conferences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] 炎症性腸疾患における小胞体ストレス応答の関与について2021

    • Author(s)
      中山哲雄、栗林志行、岩脇隆夫、平戸純子、深井泰守、富澤琢、橋本悠、田中寛人、草野元康、浦岡俊夫
    • Organizer
      第101回日本消化器内視鏡学会総会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] ATF4の翻訳活性化機構に赤色蛍光/発光レポーターを応用した統合ストレス可視化モデルマウスの開発2021

    • Author(s)
      赤井良子、黒田絵莉子、濱嶋尚代、岩脇隆夫
    • Organizer
      第73回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] ENDOPLASMIC RETICULUM STRESS IS ASSOCIATED WITH CLINICAL FEATURES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE2021

    • Author(s)
      Tetsuo Nakayama, Shiko Kuribayashi, Takao Iwawaki, Junko Hirato, Ryoko Akai, Yasumori Fukai, Hirohito Tanaka, Taku Tomizawa, Yu Hashimoto, Motoyasu Kusano, Toshio Uraoka
    • Organizer
      Digestive Disease Week 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03334
  • [Presentation] ストレス可視化モデルマウスの開発と疲労研究への応用2020

    • Author(s)
      岩脇隆夫、赤井良子
    • Organizer
      第16回日本疲労学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] IRE1α Is Essential for Podocyte Proteostasis and Mitochondrial Health2020

    • Author(s)
      Jose R. Navarro-Betancourt, Joan Papillon, Julie Guillemette, Takao Iwawaki, Andrey V. Cybulsky
    • Organizer
      KIDNEY WEEK 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] Role of IRE1α in Podocyte Proteostasis2019

    • Author(s)
      Jose R Navarro-Betancourt, Joan Papillon, Julie Guillemette, Takao Iwawaki, Andrey V Cybulsky
    • Organizer
      KIDNEY WEEK 2019
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] Comparison between endoscopic and histopathological findings in patients with ulcerative colitis2019

    • Author(s)
      Tetsuo Nakayama, Shiko Kuribayashi, Junko Hirato, Takao Iwawaki, Ko Nakata, Hirohito Tanaka, Taku Tomizawa, Hiroko Hosaka, Yasuyuki Shimoyama, Osamu Kawamura, Motoyasu Kusano, Toshio Uraoka
    • Organizer
      Digestive Disease Week 2019
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 睡眠不足モデルマウスにおける細胞ストレス応答と炎症反応の生体イメージング2019

    • Author(s)
      赤井良子、岩脇隆夫
    • Organizer
      第66回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 小胞体ストレス応答分子により制御される過食行動の分子メカニズム2019

    • Author(s)
      岩脇隆夫、赤井良子
    • Organizer
      第14回臨床ストレス応答学会大会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] ATF4の翻訳活性化機構を利用した統合ストレス可視化モデルマウスの開発2018

    • Author(s)
      赤井良子, 岩脇隆夫
    • Organizer
      住商ファーマインターナショナル株式会社in vivoイメージングフォーラム2018
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 細菌によって利用される宿主細胞の生体防御反応~小胞体ストレス応答~2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第55回日本細菌学会中部支部学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 細胞ストレスおよび炎症可視化モデルマウスの開発とその性能2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第342回熊本大学・発生研セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] ATF4の翻訳活性化機構を利用した統合ストレス可視化モデルマウスの開発と疲労研究への応用2018

    • Author(s)
      岩脇隆夫, 赤井良子
    • Organizer
      第14回日本疲労学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 細胞ストレスおよび炎症可視化モデルマウスの開発とその性能2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第16回京都薬科大学・実験動物セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 『見えない』を『見える』にするマウス2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第20回KMU研究推進セミナー
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] ATF4の翻訳活性化機構を利用した統合ストレス可視化モデルマウスの開発2018

    • Author(s)
      赤井良子, 岩脇隆夫
    • Organizer
      第65回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 異常行動およびエイジングにまで拡がる小胞体ストレス研究の新展開2017

    • Author(s)
      岩脇隆夫
    • Organizer
      東京大学大学院薬学系研究科遺伝学教室主催研究集会2017
    • Place of Presentation
      和光純薬湯河原研修所(静岡県熱海市)
    • Year and Date
      2017-03-12
    • Data Source
      KAKENHI-PROJECT-15K15038
  • [Presentation] 酸化ストレス可視化マウスを用いた脳マラリアの新しい評価法2014

    • Author(s)
      今井孝、岩脇隆夫、赤井良子、鈴江一友、平井誠、谷口委代、岡田紘子、久枝一
    • Organizer
      第83回日本寄生虫学会大会
    • Place of Presentation
      愛媛大学
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] The role of ER stress responses in the control of blood glucose and the biosynthesis of insulin2014

    • Author(s)
      Ryoko Akai, Takao Iwawaki
    • Organizer
      7th APOCB Congress and ASCB Workshops
    • Place of Presentation
      Biopolis(シンガポール)
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins2014

    • Author(s)
      Takao Iwawaki, Daisuke Oikawa
    • Organizer
      7th APOCB Congress and ASCB Workshops
    • Place of Presentation
      Biopolis(シンガポール)
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 胎盤でのCathepsin遺伝子発現制御におけるIRE1αおよびXBP1の役割2013

    • Author(s)
      岩脇隆夫、及川大輔
    • Organizer
      第60回北関東医学会総会
    • Place of Presentation
      群馬大学
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Fatty acid flux regulates IRE1α activity to control the NLRP3 inflammasome in myeloid cells2013

    • Author(s)
      Megan Robblee, Jess P. Abate, Alex Samocha, Takao Iwawaki, Suneil K. Koliwad
    • Organizer
      The 2013 Meeting on Metabolic Signaling & Disease
    • Place of Presentation
      Cold Spring Harbor(米国)
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Intrinsically disordered regions in handling of misfolded/unfolded proteins in the ER2013

    • Author(s)
      Takao Iwawaki
    • Organizer
      The 2nd ISIDP International Symposium
    • Place of Presentation
      RIKEN, Yokohama
    • Year and Date
      2013-01-23
    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能2013

    • Author(s)
      岩脇隆夫
    • Organizer
      第86回日本生化学会バイオインダストリーセミナー
    • Place of Presentation
      パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞内異常タンパク質代謝における天然変性領域の役割2012

    • Author(s)
      岩脇隆夫
    • Organizer
      新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」第2回公開シンポジウム
    • Place of Presentation
      千里ラィフサイェンスセンター(招待講演)
    • Year and Date
      2012-01-25
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 小胞体ストレスを『より簡便』に検出する方法2012

    • Author(s)
      岩脇隆夫
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(招待講演)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能2012

    • Author(s)
      岩脇隆夫
    • Organizer
      細胞センサーの分子機構・相互作用・ネットワーク研究会
    • Place of Presentation
      生理学研究所
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 酸化ストレス可視化モデルマウスの開発2012

    • Author(s)
      岩脇隆夫
    • Organizer
      第8回日本疲労学会総会・学術集会
    • Place of Presentation
      国立スポーツ科学センター
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] IRE1αとIRE1βによる小胞体ストレス感知機構の違い2012

    • Author(s)
      岩脇 隆夫
    • Organizer
      第7回小胞体ストレス研究会
    • Place of Presentation
      広島大学
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Presentation] 胎盤における小胞体ストレス応答分子の機能2012

    • Author(s)
      岩脇隆夫
    • Organizer
      第4回群馬分子医学研究会
    • Place of Presentation
      群馬大学
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 動物個体における小胞体ストレスと酸化ストレスのイメージング技術の開発2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第10回国際バイオEXPO
    • Place of Presentation
      東京ビッグサイト
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] Screening for XBP1 splicing-associated RNA ligase2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] Transgenic mouse models for monitoring cellular stress2011

    • Author(s)
      Iwawaki Takao
    • Organizer
      奈良先端未来開拓コロキウム"Protein and Organelle Dynamics under Cellular Stress Conditions"
    • Place of Presentation
      奈良先端科学技術大学院大学(招待講演)
    • Year and Date
      2011-05-31
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 酸化ストレス可視化モデルマウスの開発2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第6回IVISユーザー会
    • Place of Presentation
      パシフィコ横浜(招待講演)
    • Year and Date
      2011-11-04
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] XBP1のスプライシングに関わるRNAリガーゼのスクリーニング2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第63回日本細胞生物学会
    • Place of Presentation
      北海道大学
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] マウス個体における酸化ストレスイメージングシステムの開発2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第6回臨床ストレス応答学会
    • Place of Presentation
      名古屋大学医学部
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 膵臓β細胞でのインスリン産生におけるIRE1とATF6の役割2010

    • Author(s)
      藤岡洋美、土屋雄一、斉藤美知子、岩脇隆夫、森和俊、河野憲二
    • Organizer
      第33回日本分子生物学会・第83回日本生化学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] The role of ER stress responses in the control of blood glucose levels and the biosynthesis of insulin2010

    • Author(s)
      Takao Iwawaki
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] The role of ER stress responses in the control of blood glucose levels and the biosynthesis of insulin2010

    • Author(s)
      Takao Iwawaki, Akira Hosoda, Ryoko Akai, Mio Tokuda
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      in Nara
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 血糖値調節およびインスリン生合成における小胞体ストレス応答の役割2010

    • Author(s)
      岩脇隆夫
    • Organizer
      第5回臨床ストレス応答学会
    • Place of Presentation
      徳島
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 血糖値調節およびインスリン生合成における小胞体ストレス応答の役割2010

    • Author(s)
      岩脇隆夫、細田章、赤井良子、徳田美緒
    • Organizer
      第33回日本分子生物学会・第83回日本生化学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 血糖値調節およびインスリン生合成における小胞体ストレス応答の役割2010

    • Author(s)
      岩脇隆夫、細田章、赤井良子、徳田美緒
    • Organizer
      第5回臨床ストレス応答学会
    • Place of Presentation
      徳島大
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 胎盤形成における小胞体ストレスセンサーとビタミンEの役割2009

    • Author(s)
      岩脇隆夫
    • Organizer
      エーザイ株式会社第12回Vitamin E Update Forum
    • Place of Presentation
      如水会館、東京
    • Year and Date
      2009-08-31
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Contribution of IRE1 signaling to placental angiogenesis and functuion for embryogenesis2009

    • Author(s)
      岩脇隆夫
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Genome-wide screening method for the cleavage target of IRE1alpha2009

    • Author(s)
      Daisuke Oikawa, Mio Tokuda, Akira Hosoda, Takao Iwawaki
    • Organizer
      The 32nd Annual Meeting of the Molecular Biology Society of Japan
    • Place of Presentation
      in Yokohama
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland2009

    • Author(s)
      Akira Hosoda, Mio Tokuda, Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Phenotype analysis of IRE1 alpha conditional knockout mice2009

    • Author(s)
      Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 胎盤形成における小胞体ストレスセンサーとビタミンEの役割2009

    • Author(s)
      岩脇隆夫
    • Organizer
      エーザイ株式会社 第12回 Vitamin E Update Forum
    • Place of Presentation
      東京
    • Year and Date
      2009-08-31
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] PSG遺伝子群の胎盤発現に対するIRE1a-XBP1経路の貢献2009

    • Author(s)
      及川大輔、赤井良子、岩脇隆夫
    • Organizer
      第61回日本細胞生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland2009

    • Author(s)
      Akira Hosoda, Mio Tokuda, Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Organizer
      The 32nd Annual Meeting of the Molecular Biology Society of Japan
    • Place of Presentation
      in Yokohama
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Contribution of IRE1alpha-XBP1 pathway to the placental expression of PSG genes2009

    • Author(s)
      Daisuke Oikawa, Ryoko Akai, Takao Iwawaki
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine, Poster Presentation
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Contribution of IRE1 signaling to placental angiogenesis and function for embryogenesis2009

    • Author(s)
      Takao Iwawaki, Ryoko Akai, Shinya Yamanaka, Kenji Kohno
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 群馬大学で名付けられた遺伝子、IRE1

    • Author(s)
      岩脇隆夫
    • Organizer
      第61回北関東医学会総会
    • Place of Presentation
      群馬大(群馬県前橋市)
    • Year and Date
      2014-09-25 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能

    • Author(s)
      岩脇隆夫
    • Organizer
      岡山大&理研ジョイントシンポジウム「最先端計測技術のトレンド2013」
    • Place of Presentation
      岡山大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 動物個体レベルでみる小胞体ストレス応答分子IRE1αの役割

    • Author(s)
      岩脇隆夫
    • Organizer
      第122回東京大学生命環境科学セミナー
    • Place of Presentation
      東京大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 小胞体ストレス応答不全による糖尿病発症機構の解明

    • Author(s)
      斉藤美知子、土屋雄一、岩脇隆夫、森和俊、宮崎純一、河野憲二
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Unfolded protein response is differently activated by membrane lipid saturation and unfolded proteins in the endoplasmic reticulum

    • Author(s)
      Nozomu Kono, Yuto Kitai, Hiroyuki Ariyama, Daisuke Oikawa, Takao Iwawaki, Hiroyuki Arai
    • Organizer
      FASEB SRC: Phospholipid Cell Signaling and Metabolism in Inflammation and Cancer
    • Place of Presentation
      Niagara Falls (USA)
    • Year and Date
      2014-06-01 – 2014-06-06
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] メチル水銀誘発性神経細胞死における小胞体ストレスの関与

    • Author(s)
      奥田洸作、牧野堅人、外山喬士、西屋禎、岩脇隆夫、熊谷嘉人、上原孝
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      ウインクあいち
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能

    • Author(s)
      岩脇隆夫
    • Organizer
      第5回実験動物センター・テクニカルセミナー
    • Place of Presentation
      東京医科歯科大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能

    • Author(s)
      岩脇隆夫
    • Organizer
      第8回医工連携グループミーティング
    • Place of Presentation
      群馬大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] インスリン生合成に必要な膵臓ベータ細胞におけるeIF2αキナーゼとホスファターゼのバランス機構

    • Author(s)
      岩脇 隆夫、赤井 良子、細田 章、徳田 美緒
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 小胞体ストレスセンサーIRE1αによる細胞質スプライシングに必要なmRNAの構造及び配列の解析

    • Author(s)
      池端悠介、今川佑介、柳谷耕太、田丸良子、金谷重彦、岩脇隆夫、河野憲二
    • Organizer
      第66回日本細胞生物学会
    • Place of Presentation
      東大寺総合文化センター(奈良県奈良市)
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] インスリン産生細胞における小胞体ストレスセンサーIRE1alphaの生理的役割

    • Author(s)
      土屋雄一、斉藤美知子、岩脇隆夫、宮崎純一、河野憲二
    • Organizer
      第66回日本細胞生物学会
    • Place of Presentation
      東大寺総合文化センター(奈良県奈良市)
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-24390049
  • []

  • 1.  田中 貴士 (30734694)
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    # of Collaborated Products: 0 results
  • 2.  堀 修 (60303947)
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    # of Collaborated Products: 0 results
  • 3.  竹屋 元裕 (90155052)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  古山 貴文 (20802268)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  浦 大樹 (90624958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  田中 聡 (10321944)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  八田 稔久 (20238025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  清水 陽 (30808077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  坂田 ひろみ (50294666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  茂田 大地 (40974663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  友杉 充宏 (60533429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OIKAWA Daisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 13.  TAKAHASHI Yayoi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ASAI Chiaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  YOSHINO Mayuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  AKAI Ryoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  SAITO Michiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  SUZUKI Takafumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  門倉 広
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  河野 憲二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 21.  平井 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  改正 恒康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  上原 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 24.  伊藤 昭博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  熊谷 嘉人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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