BONKOBARA Makoto 盆子原誠

… Alternative Names

盆子原誠ボンコバラマコト

MAKOTO Bonkobara 盆子原誠

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Researcher Number	50343611
Other IDs
Affiliation (Current)	2025: 日本獣医生命科学大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 日本獣医生命科学大学, 獣医学部, 教授 2015 – 2023: 日本獣医生命科学大学, 獣医学部, 教授 2011 – 2014: 日本獣医生命科学大学, 獣医学部, 准教授 2006 – 2011: Nippon Veterinary and Life Science University, Department of Veterinary Science, Lecturer, 獣医学部, 講師 2006 – 2007: 日本獣医生命科学大学, 獣医学研究科, 講師 … More 2005: Nippon Veterinary & Animal Science University, Department of Veterinary Medicine, Assistant Professor, 獣医学部, 講師 2003 – 2004: 日本獣医畜産大学, 獣医学部, 助手 2002: 日本獣医畜産大学, 獣医畜産学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Clinical veterinary science / Applied veterinary science / Applied veterinary science Except Principal Investigator Veterinary medical science / Clinical veterinary science / Basic veterinary science/Basic zootechnical science / Basic Section 42020:Veterinary medical science-related
Keywords	Principal Investigator 犬 / 肥満細胞腫 / KIT変異 / 耐性 / チロシンキナーゼ阻害剤 / イマチニブ / チロシンキナーゼ / 猫 / 樹状細胞 / 分子糊 … More / SHP099 / SHP2 / トセラニブ / 個別化治療 / 耐性化 / 獣医腫瘍学 / 獣医臨床病理学 / 獣医学 / KIT / co-stimulation / antigen / suppression / T-cells / dendritic cells / 共刺激 / 抗原 / 抑制 / T細胞 / 転移 / 上皮性腫瘍 / 血中循環腫瘍細胞 / 顆粒細胞腫瘍 / 遺伝子動態 / 形質転換機構 / 黒色腫 / 顆粒細胞腫 / Oncogene addiction / ダサチニブ / キナーゼ / oncogene addiction / 組織球性肉腫 / c-kit変異 / プロテアソーム阻害剤 / NFkB / 分子標的薬 / 悪性黒色腫 / 分子標的療法 / c-kit / 白血球 / Dec2FR / プロモーター活性 / DNAワクチン / ゲノム / ランゲルハンス細胞 / Dectin-2 / ウシ / 転写活性 / プロモーター … More Except Principal Investigator AIM / 免疫 / アポトーシス / 腫瘍 / Th1 / がん / 犬 / ウイルス / 内科 / 病態 / macrophage / 組織球 / CD5L / 癌 / 獣医学 / ヌードマウス / イヌ / 組織球性肉腫 / マクロファージ / Persistent infection / Evasion of immune-system / Proteolysis / Ubiquitin / 持続感染 / 免疫回避機構 / 蛋白質分解 / ユビキチン / insulin signal / fatty acid synthase / gluconeogenetic enzyme / glycolytic enzyme / insulin resistance / diabetes mellitus / obesity / cat / リンゴ酸デヒドロゲナーゼ / インスリンシグナル / 脂肪酸合成酵素 / 糖新生系酵素 / 解糖系酵素 / インスリン抵抗性 / 糖尿病 / 肥満 / 猫 / Dndritic cell-mediated therapy / Babesiosis / Malignant melanoma / Th2 cell / Induction into Th1 / Th2 cell differentiation / Stimulating factor / Established cell / Dendritic cell / Antigen presenting cell / 細胞免疫療法 / Th2 / Th2分化・誘導 / 分化・誘導 / 免疫細胞療法 / バベシア症 / 悪性黒色腫 / Th2細胞への分化・誘導 / Th2細胞 / 疾患時のTh1 / 誘導物質 / 株化細胞 / 樹状細胞 / 抗原提示細胞 / 乳癌 / 横紋筋肉腫 / 炎症性乳癌 / がん幹細胞 / 自己複製能 / 癌幹細胞 / ネコＡＢ式血液型 / イヌDEA式血液型 / 遺伝子発現解析 / 責任候補遺伝子 / ゲノムワイド関連解析 / 輸血副作用 / ネコAB / イヌDEA1.1 / 遺伝子 / 抗原エピトープ / ネコＡＢ / イヌＤＥＡ / 血液型 / 輸血 / 小動物 / 血液型物質 / 遺伝子検査 / 輸血医療 / ウイルス複製制御 / ノンコーディングRNA / 遺伝子制御 / ncRNA / ネコ / 感染症 Less

犬TP53変異扁平上皮癌における「未成熟終止コドン読み飛ばし」に基づく治療戦略の創出Principal Investigator
- Principal Investigator
  
  盆子原誠
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Nippon Veterinary and Life Science University
Development of a novel therapeutic strategy for KIT mutation-positive canine mast cell tumor using molecular gluePrincipal Investigator
- Principal Investigator
  
  盆子原誠
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Nippon Veterinary and Life Science University
Analysis of diversity in tyrosine kinase inhibitor resistance in mast cell tumors toward establishment of individualized therapyPrincipal Investigator
- Principal Investigator
  
  Bonkobara Makoto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Nippon Veterinary and Life Science University
AIM expression, mutation and function in canine histiocytic sarcoma
- Principal Investigator
  
  Yonezawa Tomohiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Studies on the mechanisms and therapeutic approach for resistance of tyrosine kinase inhibitors in mast cell tumourPrincipal Investigator
- Principal Investigator
  
  BONKOBARA MAKOTO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
The role of canine AIM in histiocytic sarcoma
- Principal Investigator
  
  Yonezawa Tomohiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo
Identification and clinical application of cancer stem cells derived from canine refractory cancers
- Principal Investigator
  
  Michishita Masaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
Establishment of detection system for canine circulating tumor cellPrincipal Investigator
- Principal Investigator
  
  BONKOBARA Makoto
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
Molecular analysis and development of a DNA-testing method for erythrocyte blood group antigens
- Principal Investigator
  
  OMI TOSHINORI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
Changes of DNA profile in canine granular tumor cells transformed to melanoma cellsPrincipal Investigator
- Principal Investigator
  
  BONKOBARA Makoto
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
Analysis of oncogene addiction and development of molecular-targeted therapy for small animal tumoursPrincipal Investigator
- Principal Investigator
  
  BONKOBARA Makoto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
Analysis of aberrantly activated receptor tyrosine kinase and development of molecular targeting therapy in small animals with malignancies.Principal Investigator
- Principal Investigator
  
  MAKOTO Bonkobara
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
Analysis of regulation on feline infectious peritonitis virus replication by RNA interference
- Principal Investigator
  
  TANAKA Yoshikazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Nippon Veterinary and Life Science University
Study for inhibitory regulation of auto reactive T-cell by DC-HILPrincipal Investigator
- Principal Investigator
  
  BONKOBARA Makoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
家畜の感染症に対する表皮ランゲルハンス細胞を標的としたDNAワクチンの開発Principal Investigator
- Principal Investigator
  
  盆子原誠
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
Studies on regulatory mechanism of Th1/Th2 cell differentiation by antigen presenting cell (APC) and onAPC-mediated immunotherapy
- Principal Investigator
  
  ONO Kenichiro
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Clinical veterinary science
- Research Institution
  The University of Tokyo
Analysis of onset mechanism of obesity and diabetes in cats and its application to veterinary medicine
- Principal Investigator
  
  ARAI Toshiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
Analysis for selective ubiquitination of host immune proteins by Bovine Herpes virus type4 proteins
- Principal Investigator
  
  TANAKA Yoshikazu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Nippon Veterinary & Animal Science University
イヌDectin-2プロモーターによる新しい抗腫瘍DNAワクチン開発の基礎研究Principal Investigator
- Principal Investigator
  
  盆子原誠
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Nippon Veterinary and Life Science University

[Book] Veterinary Oncology2014
- Author(s)
  盆子原誠
- Publisher
  インターズー
- Data Source
  KAKENHI-PROJECT-25660244
[Book] 犬と猫の早期疾病診断学2011
- Author(s)
  盆子原誠, 他
- Publisher
  チクサン出版社
- Data Source
  KAKENHI-PROJECT-21580395
[Book] 犬と猫の早期疾病診断学(予防動物医学研究会編)2011
- Author(s)
  盆子原誠, 他多数
- Total Pages
  206
- Publisher
  チクサン出版社
- Data Source
  KAKENHI-PROJECT-21580395
[Journal Article] Whole exome and transcriptome analysis revealed the activation of ERK and Akt signaling pathway in canine histiocytic sarcoma2023
- Author(s)
  Asada H, Tani A, Sakuma H, Hirabayashi M, Matsumoto Y, Watanabe K, Tsuboi M, Yoshida S, Harada K, Uchikai T, Goto-Koshino Y, Chambers JK, Ishihara G, Kobayashi T, Irie M, Uchida K, Ohno K, Bonkobara M, Tsujimoto H, Tomiyasu H.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 8512-8512
- DOI
  10.1038/s41598-023-35813-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06031, KAKENHI-PROJECT-23K23778
[Journal Article] Establishment of a BRAF V595E-mutant canine prostate cancer cell line and the antitumor effects of MEK inhibitors against canine prostate cancer2023
- Author(s)
  Kobayashi Masanori、Onozawa Moe、Watanabe Shiho、Nagashima Tomokazu、Tamura Kyoichi、Kubo Yoshiaki、Ikeda Akiko、Ochiai Kazuhiko、Michishita Masaki、Bonkobara Makoto、Kobayashi Masato、Hori Tatsuya、Kawakami Eiichi
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: - Issue: 2 Pages: 1-10
- DOI
  10.1111/vco.12879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06429, KAKENHI-PROJECT-22K05996, KAKENHI-PROJECT-22K06031, KAKENHI-PROJECT-23K05561, KAKENHI-PROJECT-21K14989
[Journal Article] A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis2021
- Author(s)
  Tani Hiroyuki、Miyamoto Ryo、Noguchi Syunya、Kurita Sena、Nagashima Tomokazu、Michishita Masaki、Yayoshi Naoko、Tamura Kyoichi、Bonkobara Makoto
- Journal Title
  
  BMC Veterinary Research
  
  Volume: 17 Issue: 1 Pages: 147-147
- DOI
  10.1186/s12917-021-02864-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06429, KAKENHI-PROJECT-19H03131, KAKENHI-PROJECT-19J15532, KAKENHI-PROJECT-19K06391
[Journal Article] Commitment toward cell death by activation of autophagy with survivin inhibitor YM155 in two canine squamous cell carcinoma cell lines with high expression of survivin2021
- Author(s)
  Miyamoto Ryo、Tani Hiroyuki、Ikeda Tomoyo、Saima Hono、Tamura Kyoichi、Bonkobara Makoto
- Journal Title
  
  Research in Veterinary Science
  
  Volume: 135 Pages: 412-415
- DOI
  10.1016/j.rvsc.2020.10.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06429, KAKENHI-PROJECT-19H03131, KAKENHI-PROJECT-19J15532
[Journal Article] Molecular characterization of canine <scp>SHP2</scp> mutants and anti‐tumour effect of <scp>SHP2</scp> inhibitor, <scp>SHP099</scp> , in a xenograft mouse model of canine histiocytic sarcoma2021
- Author(s)
  Tani Hiroyuki、Miyamoto Ryo、Nagashima Tomokazu、Michishita Masaki、Tamura Kyoichi、Bonkobara Makoto
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: 20 Issue: 1 Pages: 109-117
- DOI
  10.1111/vco.12751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06391, KAKENHI-PROJECT-19H03131
[Journal Article] Foxp3+ Regulatory T Cells Associated with CCL17/CCR4 Expression in Carcinomas of Dogs2020
- Author(s)
  Shingo Maeda, Maho Nakazawa, Mona Uchida, Ryohei Yoshitake, Takayuki Nakagawa, Ryohei Nishimura, Ryo Miyamoto, Makoto Bonkobara, Tomohiro Yonezawa, Yasuyuki Momoi
- Journal Title
  
  Veterinary Pathology
  
  Volume: In press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03131
[Journal Article] Nimustine Treatment of 11 Cases of Canine Histiocytic Sarcoma.2020
- Author(s)
  Tani H, Kurita S, Miyamoto R, Sawada H, Fujiwara-Igarashi A, Michishita M, Azakami D, Hasegawa D, Tamura K, Bonkobara M.
- Journal Title
  
  J Am Anim Hosp Assoc.
  
  Volume: 56 Issue: 3 Pages: 146-146
- DOI
  10.5326/jaaha-ms-6959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06429, KAKENHI-PROJECT-19H03132, KAKENHI-PROJECT-19J15532, KAKENHI-PROJECT-19H03131
[Journal Article] Foxp3+ Regulatory T Cells Associated With CCL17/CCR4 Expression in Carcinomas of Dogs.2020
- Author(s)
  Maeda S, Nakazawa M, Uchida M, Yoshitake R, Nakagawa T, Nishimura R, Miyamoto R, Bonkobara M, Yonezawa T, Momoi Y
- Journal Title
  
  Veterinary Pathology
  
  Volume: 29 Issue: 4 Pages: 1-10
- DOI
  10.1177/0300985820921535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J15532, KAKENHI-PROJECT-18H02340, KAKENHI-PROJECT-19H03131
[Journal Article] The secondary KIT mutation p.Ala510Val in a cutaneous mast cell tumour carrying the activating mutation p.Asn508Ile confers resistance to masitinib in dogs2020
- Author(s)
  Gentilini Fabio、Turba Maria Elena、Dally Claire、Takanosu Masamine、Kurita Sena、Bonkobara Makoto
- Journal Title
  
  BMC Veterinary Research
  
  Volume: 16 Issue: 1 Pages: 64-64
- DOI
  10.1186/s12917-020-02284-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03131
[Journal Article] Anti-tumour activity of oncolytic reovirus against canine histiocytic sarcoma cells2019
- Author(s)
  Igase Masaya、Shousu Kazuha、Fujiki Noriyuki、Sakurai Masashi、Bonkobara Makoto、Hwang Chung C.、Coffey Matt、Noguchi Shunsuke、Nemoto Yuki、Mizuno Takuya
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: 17 Issue: 2 Pages: 184-193
- DOI
  10.1111/vco.12468
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14588, KAKENHI-PROJECT-16J06655, KAKENHI-PROJECT-19H03131
[Journal Article] Genetic alterations of KIT during clonal expansion and subsequent acquisition of resistance to toceranib in a canine mast cell tumor cell line.2019
- Author(s)
  Kurita S, Miyamoto R, Tani H, Kobayashi M, Sasaki T, Tamura K, Bonkobara M.
- Journal Title
  
  J Vet Pharmacol Ther.
  
  Volume: 42 Issue: 6 Pages: 673-681
- DOI
  10.1111/jvp.12816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06429, KAKENHI-PROJECT-19H03131, KAKENHI-PROJECT-19H03132, KAKENHI-PROJECT-19J15532
[Journal Article] Canine histiocytic sarcoma cell lines with SHP2 p.Glu76Gln or p.Glu76Ala mutations are sensitive to allosteric SHP2 inhibitor SHP099.2019
- Author(s)
  Tani H, Kurita S, Miyamoto R, Ochiai K, Tamura K, Bonkobara M.
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: - Issue: 2 Pages: 161-168
- DOI
  10.1111/vco.12524
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06390, KAKENHI-PROJECT-19K06429, KAKENHI-PROJECT-19H03131, KAKENHI-PROJECT-19H03132, KAKENHI-PROJECT-19J15532
[Journal Article] Effect of dasatinib in a xenograft mouse model of canine histiocytic sarcoma and in vitro expression status of its potential target EPHA22018
- Author(s)
  Ito K, Miyamoto R, Tani H, Kurita S, Kobayashi M, Tamura K, Bonkobara M
- Journal Title
  
  J Vet Pharmacol Ther
  
  Volume: 41 Issue: 1
- DOI
  10.1111/jvp.12449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04601
[Journal Article] A decrease in ubiquitination and resulting prolonged life-span of KIT underlies the KIT overexpression-mediated imatinib resistance of KIT mutation-driven canine mast cell tumor cells2017
- Author(s)
  Kobayashi M, Kuroki S, Kurita S, Miyamoto R, Tani H, Tamura K, Bonkobara M
- Journal Title
  
  Oncol Rep
  
  Volume: 38 Issue: 4 Pages: 2543-2550
- DOI
  10.3892/or.2017.5865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04601
[Journal Article] MicroRNA expression profiling in canine prostate cancer.2017
- Author(s)
  Kobayashi M, Saito A, Tanaka Y, Michishita M, Kobayashi M, Irimajiri M, Kaneda T, Ochiai K, Bonkobara M, Takahashi K, Hori T, Kawakami E.
- Journal Title
  
  J Vet Med Sci.
  
  Volume: In press
- NAID
  130005549028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04601
[Journal Article] Identification of a secondary mutation in the KIT kinase domain correlated with imatinib-resistance in a canine mast cell tumor2017
- Author(s)
  Nakano Y, Kobayashi M, Bonkobara M, Takanosu M
- Journal Title
  
  Vet Immunol Immunopathol
  
  Volume: 188 Pages: 84-88
- DOI
  10.1016/j.vetimm.2017.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04601
[Journal Article] Properties of the feline tumour suppressor reduced expression in immortalized cells (REIC/Dkk-3).2017
- Author(s)
  Ochiai K, Oda H, Shono S, Kato Y, Sugihara S, Nakazawa S, Azakami D, Michishita M, Onozawa E, Bonkobara M, Sako T, Shun-Ai L, Ueki H, Watanabe M, Omi T.
- Journal Title
  
  Vet Comp Oncol
  
  Volume: In press Issue: 4 Pages: 1181-1186
- DOI
  10.1111/vco.12254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K07754
[Journal Article] Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines2017
- Author(s)
  Kato Yuiko、Ochiai Kazuhiko、Kawakami Shota、Nakao Nobuhiro、Azakami Daigo、Bonkobara Makoto、Michishita Masaki、Morimatsu Masami、Watanabe Masami、Omi Toshinori
- Journal Title
  
  BMC Veterinary Research
  
  Volume: 13 Issue: 1 Pages: 170-170
- DOI
  10.1186/s12917-017-1094-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08053, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-15H04297, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K07754
[Journal Article] Oncocytic carcinoma of the salivary gland in a dog.2017
- Author(s)
  Nakahira R, Michishita M, Kato M, Okuno Y, Hatakeyama H, Yoshimura H, Azakami D, Ochiai K, Bonkobara M, Takahashi K.
- Journal Title
  
  J Vet Diagn Invest
  
  Volume: 29 Issue: 1 Pages: 105-108
- DOI
  10.1177/1040638716673126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-26292161
[Journal Article] MicroRNA expression profiling in canine prostate cancer2017
- Author(s)
  Kobayashi M, Saito A, Tanaka Y, Michishita M, Kobayashi M, Irimajiri M, Kaneda T, Ochiai K, Bonkobara M, Takahashi K, Hori T, Kawakami E
- Journal Title
  
  Journal of Veterianry Medical Science
  
  Volume: 79 Issue: 3 Pages: 719-725
- DOI
  10.1177/1040638717698179
- NAID
  130005549028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26292161
[Journal Article] Selective growth inhibition by suppression of F1Fo ATPase in canine malignant melanoma cell lines.2017
- Author(s)
  Kuroki S, Kobayashi M, Tani H, Miyamoto R, Kurita S, Tamura K, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  J Vet Pharmacol Ther
  
  Volume: 40 Issue: 1 Pages: 101-104
- DOI
  10.1111/jvp.12336
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K18798
[Journal Article] Receptor tyrosine kinase KIT: Prognostic and therapeutic involvement in canine mast cell tumours.2016
- Author(s)
  Takeuchi Y, Bonkobara M.
- Journal Title
  
  Vet J
  
  Volume: 210 Pages: 5-6
- DOI
  10.1016/j.tvjl.2015.07.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04601
[Journal Article] The canine prostate cancer cell line CHP-1 shows over-expression of the co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α2016
- Author(s)
  Azakami, D., Nakahira, R., Kato, Y., Michishita, M., Kobayashi, M., Onozawa, E., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M., Ishioka, K., Sako, T., Ochiai, K., and Omi, T.
- Journal Title
  
  Veterinary and Compapative Oncology
  
  Volume: 印刷中 Issue: 2 Pages: 557-562
- DOI
  10.1111/vco.12199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07754, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15H04297
[Journal Article] Recent developments in veterinary diagnostics: Current status and future potential.2016
- Author(s)
  Bonkobara M.
- Journal Title
  
  Vet J
  
  Volume: 215 Pages: 1-2
- DOI
  10.1016/j.tvjl.2016.08.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04601
[Journal Article] Molecular Characterization of the Cytidine Monophosphate-N-Acetylneuraminic Acid Hydroxylase (CMAH) Gene Associated with the Feline AB Blood Group System.2016
- Author(s)
  Omi T, Nakazawa S, Udagawa C, Tada N, Ochiai K, Chong YH, Kato Y, Mitsui H, Gin A, Oda H, Azakami D, Tamura K, Sako T, Inagaki T, Sakamoto A, Tsutsui T, Bonkobara M, Tsuchida S, Ikemoto S.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 10 Pages: e0165000-e0165000
- DOI
  10.1371/journal.pone.0165000
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-15K18798, KAKENHI-PROJECT-16K08062
[Journal Article] Molecular cloning of canine co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α (SGTA) and investigation of its ability to suppress androgen receptor signalling in androgen-independent prostate cancer.2015
- Author(s)
  Kato, Y., Ochiai, K., Michishita, M., Azakami, D., Nakahira, R., Morimatsu, M., Ishiguro-Oonuma, T., Yoshikawa, Y., Kobayashi, M., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M., and Omi, T.
- Journal Title
  
  The Vwterinary Journal
  
  Volume: 206 Issue: 2 Pages: 145-148
- DOI
  10.1016/j.tvjl.2015.08.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07754, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-13J10765, KAKENHI-PROJECT-26292161
[Journal Article] <b>Polymorphisms of canine BRCA2 BRC repeats affecting interaction with </b><b>RAD51 </b>2015
- Author(s)
  Kazuhiko Ochiai, Toshina Ishiguro-Oonuma, Yasunaga Yoshikawa, Chihiro Udagawa, Yuiko Kato, Masami Watanabe, Makoto Bonkobara, Masami Morimatsu, Toshinori Omi
- Journal Title
  
  Biomed. Res.
  
  Volume: 36 Issue: 2 Pages: 155-158
- DOI
  10.2220/biomedres.36.155
- NAID
  130005065275
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-26660243, KAKENHI-PROJECT-15H04601
[Journal Article] Molecular changes associated with the development of resistance to imatinib in an imatinib-sensitive canine neoplastic mast cell line carrying a KIT c.1523A>T mutation2015
- Author(s)
  Kobayashi M, Kuroki S, Tanaka Y, Moriya Y, Kozutumi Y, Uehara Y, Ono K, Tamura K, Washizu T, Bonkobara M.
- Journal Title
  
  Eur J Haematol.
  
  Volume: In press Issue: 6 Pages: 524-31
- DOI
  10.1111/ejh.12526
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24380173, KAKENHI-PROJECT-15K18798, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-13J10765
[Journal Article] Dysregulation of tyrosine kinases and use of imatinib in small animal practice2015
- Author(s)
  Bonkobara M.
- Journal Title
  
  Vet J.
  
  Volume: In press Issue: 2 Pages: 180-188
- DOI
  10.1016/j.tvjl.2014.12.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24380173
[Journal Article] The genetic association study between polymorphisms in uncoupling protein 2 and uncoupling protein 3 and metabolic data in dogs.2014
- Author(s)
  Udagawa C, Tada N, Asano J, Ishioka K, Ochiai K, Bonkobara M, Tsuchida S, Omi T.
- Journal Title
  
  BMC Res Notes.
  
  Volume: 7 Issue: 1 Pages: 904-904
- DOI
  10.1186/1756-0500-7-904
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24380173
[Journal Article] Molecular Cloning and Gene Expression of Canine Apoptosis Inhibitor of Macrophage2014
- Author(s)
  Tomura S, Uchida M, Yonezawa T, Kobayashi M, Bonkobara M, Arai S, Miyazaki T, Tamahara S, Matsuki N.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 76 Issue: 12 Pages: 1641-1645
- DOI
  10.1292/jvms.14-0166
- NAID
  130004684872
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J10765, KAKENHI-PROJECT-24380161, KAKENHI-PROJECT-24380173, KAKENHI-PROJECT-25660251
[Journal Article] Analysis of mitochondrial DNA HVR1 haplotype of pure-bred domestic dogs in Japan.2013
- Author(s)
  Sugiyama S, Chong YH, Shito M, Kasuga M, Kawakami T, Udagawa C, Aoki H, Bonkobara M, Tsuchida S, Sakamoto A, Okuda H, Nagai A, Omi T.
- Journal Title
  
  Leg Med (Tokyo).
  
  Volume: 15 Issue: 6 Pages: 303-309
- DOI
  10.1016/j.legalmed.2013.08.005
- Data Source
  KAKENHI-PROJECT-24380173
[Journal Article] Identification of dasatinib as an in vitro potent growth inhibitor of canine histiocytic sarcoma cells2013
- Author(s)
  Ito K, Kuroki S, Kobayashi M, Ono K, Washizu T, Bonkobara M
- Journal Title
  
  Veterinary Journal
  
  Volume: (In press) Issue: 3 Pages: 536-540
- DOI
  10.1016/j.tvjl.2012.12.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380173
[Journal Article] Validation of the prognostic value of histopathological grading or c-kit mutation in canine cutaneous mast cell tumours: a retrospective cohort study2013
- Author(s)
  Takeuchi Y, Fujino Y, Watanabe M, Takahashi M, Nakagawa T, Takeuchi A, Bonkobara M, Kobayashi T, Ohno K, Uchida K, Asano K, Nishimura R, Nakayama H, Sugano S, Ohashi Y, Tsujimoto H
- Journal Title
  
  Vet J
  
  Volume: 196 Issue: 3 Pages: 492-498
- DOI
  10.1016/j.tvjl.2012.11.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22688026, KAKENHI-PROJECT-23780318, KAKENHI-PROJECT-24380173
[Journal Article] The proteasome inhibitor bortezomib inhibits the growth of canine malignant melanoma cells in vitro and in vivo.2013
- Author(s)
  Ito K, Kobayashi M, Kuroki S, Sasaki Y, Iwata T, Mori K, Kuroki T, Ozawa Y, Tetsuka M, Nakagawa T, Hiroi T, Yamamoto H, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  Vet J.
  
  Volume: ３ Issue: 3 Pages: 577-582
- DOI
  10.1016/j.tvjl.2013.08.003
- Data Source
  KAKENHI-PROJECT-24380173
[Journal Article] Imatinib-associated tumour response in a dog with a non-resectable gastrointestinal stromal tumour harbouring a c-kit exon 11 deletion mutation.2013
- Author(s)
  Kobayashi M, Kuroki S, Ito K, Yasuda A, Sawada H, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  Vet J.
  
  Volume: 198 Issue: 1 Pages: 271-274
- DOI
  10.1016/j.tvjl.2013.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380173, KAKENHI-PROJECT-13J10765
[Journal Article] Establishment of a PCR analysis method for canine BRCA22012
- Author(s)
  Yoshikawa Y, Morimatsu M, Ochiai K, Okuda K, Taoda T, Chikazawa S, Shimamura A, Omi T, Bonkobara M, Orino K, Watanabe K.
- Journal Title
  
  BMC Res Notes
  
  Volume: (in press) Issue: 1 Pages: 173-173
- DOI
  10.1186/1756-0500-5-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580395, KAKENHI-PROJECT-23580399, KAKENHI-PROJECT-23780326, KAKENHI-PROJECT-24380173, KAKENHI-PROJECT-24780313
[Journal Article] Reconstruction of stratum corneum in organotypically cultured canine keratinocyte-derived CPEK cells2011
- Author(s)
  Yagihara H, Okumura T, Shiomi E, Shinozaki N, Kuroki S, Sasaki Y, Ito K, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  Veterinary Research Communications
  
  Volume: 35(7) Pages: 433-437
- Data Source
  KAKENHI-PROJECT-21580395
[Journal Article] Establishment and Characterization of Canine Rhabdomyosarcoma Cell Line, CMS-C2011
- Author(s)
  Azakami D, Shibutani H, Dohi M, Takasaki M, Ishioka K, Mori A, Momota Y, Bonkobara M, Washizu T, Michishita M, Hatakeyama H, Ogasawara S, Sako T.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 73(8) Pages: 1105-1108
- NAID
  130000677101
- Data Source
  KAKENHI-PROJECT-21580395
[Journal Article] Imatinib elicited a favorable response in a dog with a mast cell tumor carrying a c-kit c. 1523A> T mutation via suppression of constitutive KIT activation2011
- Author(s)
  Yamada O, Kobayashi M, Sugisaki O, Ishii N, Ito K, Kuroki S, Sasaki Y, Isotani M, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  Veterinary Immunology and Immunopathology
  
  Volume: 142 Pages: 101-106
- Data Source
  KAKENHI-PROJECT-21580395
[Journal Article] Canine intestinal mast cell tumor with c-kit exon 8 mutation responsive to imatinib therapy2011
- Author(s)
  Kobayashi M, Sugisaki O, Ishii N, Yamada O, Ito K, Kuroki S, Sasaki Y, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  Veterinary Journal. 2011 in press
  
  Volume: (in press) Issue: 1 Pages: 264-267
- DOI
  10.1016/j.tvjl.2011.10.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580395
[Journal Article] Imatinib elicited a favorable response in a dog with a mast cell tumor carrying a c-kit c.1523A>T mutation via suppression of constitutive KIT activation2011
- Author(s)
  Yamada O, Kobayashi M, Sugisaki O, Ishii N, Ito K, Kuroki S, Sasaki Y, Isotani M, Ono K, Washizu T, Bonkobara M
- Journal Title
  
  Veterinary Immunology and Immunopathology
  
  Volume: 142 Pages: 101-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580395
[Journal Article] Mutations in the fifth immunoglobulin-like domain of kit are common and potentially sensitive to imatinib mesylate in feline mast cell tumors2010
- Author(s)
  Isotani M, Yamada O, Lachowicz J. L, Tamura K, Yagihara H, Fujino Y, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 148(1) Pages: 144-153
- Data Source
  KAKENHI-PROJECT-21580395
[Journal Article] Expression of canine Kdap in normal, hyperplastic and neoplastic epidermis2008
- Author(s)
  Yagihara, H., Kinjo, E., Kobayashi, Y., Tsuji, A., Nishimura, Y., Shinozaki, N., Tamura, K., Isotani, M., Nakagaki, K., Takahashi, K, Ono, K, Washizu, T., Bonkobara, M.
- Journal Title
  
  Vet. J. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Comparison of surface markers among 7 cell lines from canine histiocytic sarcoma2008
- Author(s)
  Azakami, D., Bonkobara, Washizu, T., Matsuki, N., Ono, K.
- Journal Title
  
  J. Vet. Med. Sci. (submitted)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Changes of surface markers on 7 canine histiocytic sarcoma cell lines by cultivation with GM-CSF and IL-42008
- Author(s)
  Azakami, D., Bonkobara, Washizu, T., Matsuki, N., Ono, K.
- Journal Title
  
  J. Vet. Med. Sci. (submitted)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Induction of dendric cell-mediated immune response against canine malignant melanoma cells2008
- Author(s)
  Tamura, K., Yamada, M., Isotani, M., Arai, H., Yagihara, H., Ono, K., Washizu, T., Bonkobara, M.
- Journal Title
  
  Vet. J. 175
  
  Pages: 126-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Comparison of dendric cell-mediated immune responses among canine malignant cells2007
- Author(s)
  Tamura, K., Arai, H., Ueno, E., Saito, C., Yagihara, H., Isotani, M., Ono., K, Washizu, T., Bonkobara, M.
- Journal Title
  
  J. Vet. Med. Sci. 69
  
  Pages: 925-930
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Light-chain multiple myeloma in a cat2007
- Author(s)
  Yamada O, Tamura K, Yagihara H, Isotani M, Azakami M, Sawada S, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  J Vet Diagn Invest(PubMed PMID : 17609361) 19(4)
  
  Pages: 443-7
- Data Source
  KAKENHI-PROJECT-19580351
[Journal Article] Blastic natural killer cell leukaemia in a dog - A case report.2007
- Author(s)
  Bonkobara M
- Journal Title
  
  Veterinary Journal. (In press)
- Data Source
  KAKENHI-PROJECT-18580323
[Journal Article] Efficient generation of canine bone marrow-derived dendric cells2006
- Author(s)
  Isotani, M., Katsuma, K, Tamura, K., Yamada, M., Yagihara, H., Azagami, D., Ono, K., Washizu, T., Bonkobara, M.
- Journal Title
  
  J. Vet. Med. Sci. 68
  
  Pages: 809-814
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Identification and gene expression of bovine C-type lectin dectin-2.2006
- Author(s)
  Bonkobara M
- Journal Title
  
  Vet Immunol Immunopathol. 1110(1-2)
  
  Pages: 179-186
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580246
[Journal Article] Development of the polymerase chain reaction assay based on the canine genome database for detection of monoclonality in B cell lymphoma.2006
- Author(s)
  Tamura K, Yagihara H, Isotani M, Ono K, Washizu T, Bonkobara M.
- Journal Title
  
  Vet Immunol Immunopathol. 110
  
  Pages: 163-167
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Establishment and biological characterization of canine histiocytic sarcoma cell lines2006
- Author(s)
  Azakami, D., Bonkobara, M., Iida, A., Hiraiwa, M., Kato, R., Niikura, Y., Iwaki, S., Washizu, T., Matsuki, N., Ono, K.
- Journal Title
  
  J. Vet. Med. Sci. 68
  
  Pages: 1343-1346
- NAID
  130000447983
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Identification and cornification-related gene expression of canine keratinocyte differentiation-associated protein, Kdap2006
- Author(s)
  Yagihara, H., Terada, Y., Sugimoto, S., Hidaka, F., Yamada, O., Ono, K., Washizu, T., Ariizumi, K., Bonkobara, M.
- Journal Title
  
  Vet. J. 172
  
  Pages: 141-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Identification and gene expression of bovine C-type lectin dectin-22006
- Author(s)
  Bonkobara M
- Journal Title
  
  Vet Immunol Immunopathol 110(1-2)
  
  Pages: 179-86
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580246
[Journal Article] Identification and gene expression of bovine C-type lectin dectin-22006
- Author(s)
  Makoto Bonkobara
- Journal Title
  
  Veterinary Immunology and Immunopathology 110
  
  Pages: 163-167
- Data Source
  KAKENHI-PROJECT-16380214
[Journal Article] Identification and Gene Expression of Bovine C-type Lectin Dectin-2.2006
- Author(s)
  Bonkobara M.
- Journal Title
  
  Veterinary Immunology and Immunopathology (In press)
- Data Source
  KAKENHI-PROJECT-16580246
[Journal Article] Neuronal expression of keratinocyte-associated transmembrane protein-4, KCT-4, in mouse brain and its up-regulation by neurite outgrowth of Neuro-2a cells.2006
- Author(s)
  Yamada O, Tamura K, Yagihara H, Isotani M, Washizu T, Bonkobara M.
- Journal Title
  
  Neurosci Lett. 392
  
  Pages: 226-230
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] UVB radiation upregulates dectin-2 expression in epidermal Langerhans cells.2005
- Author(s)
  Bonkobara M
- Journal Title
  
  Photochemistry and Photobiology (In press)
- Data Source
  KAKENHI-PROJECT-16580246
[Journal Article] Canine Epidermal Langerhans Cells Express a and γ but not β Chains of High-Affinity IgE Receptor.2005
- Author(s)
  Bonkobara M, Miyake F, Yagihara H, Yamada O, Azakami D, Washizu T, Cruz PD Jr, Ariizumi K.
- Journal Title
  
  Veterinary Research Communications (印刷中)
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Characterization of cDNA and the genomic sequence encoding canine neural-cell adhesion molecule, CD56/N-CAM.2005
- Author(s)
  Bonkobara M, Sato T, Takahashi N, Kasahara Y, Yagihara H, Tamura K, Isotani M, Azakami D, Ono K, Washizu T.
- Journal Title
  
  Vet Immunol Immunopathol. 107
  
  Pages: 171-176
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Ultraviolet-B radiation upregulates expression of dectin-2 on epidermal Langerhans cells by activating the gene promoter.2005
- Author(s)
  Bonkobara M, Yagihara H, Yudate T, Chung JS, Washizu T, Ariizumi K, Cruz PD Jr.
- Journal Title
  
  Photochem Photobiol. 81
  
  Pages: 944-948
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Canine epidermal langerhans cells express alpha and gamma but not beta chains of high-affinity of IgE receptor2005
- Author(s)
  Bonkobara M, et al.
- Journal Title
  
  Veterinary Research Communications 29
  
  Pages: 499-505
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380214
[Journal Article] Changes in activities of enzymes related to energy metabolism in canine lymphoma cells.2005
- Author(s)
  Washizu T, Azakami D, Bonkobara M, Washizu M, Arai T.
- Journal Title
  
  Journal of Veterinary Medical Science (印刷中)
- NAID
  110003963779
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Characterization of cDNA and the genomic sequence encoding canine neural-cell adhesion molecule, CD56/N-CAM2005
- Author(s)
  Bonkobara M, et al.
- Journal Title
  
  Veterinary Immunology and Immunopathology 107
  
  Pages: 171-176
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380214
[Journal Article] Characterization of cDNA and the genomic sequence encoding canine neural-cell adhesion molecule, CD56/N-CAM2005
- Author(s)
  Makoto Bonkobara
- Journal Title
  
  Veterinary Immunology and Immunopathology 107
  
  Pages: 171-176
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380214
[Journal Article] Comparison of expression of glucokinase gene and activities of enzymes related to glucose metabolism in livers between dog and cat.2005
- Author(s)
  Tanaka T, Inoue A.Takeguchi A, Washizu T, Bonkobara M, Arai T.
- Journal Title
  
  Veterinary Research Communications (印刷中)
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Characterization of cDNA and the genomic sequence encoding canine neural-cell adhesion molecule, CD56/N-CAM.2005
- Author(s)
  Bonkobara, M. et al.
- Journal Title
  
  Vet.Immunol.Immunopathol. 107
  
  Pages: 171-176
- Data Source
  KAKENHI-PROJECT-16208031
[Journal Article] Identification and cornification-related gene expression of canine keratinocyte differentiation-associated protein, Kdap.2005
- Author(s)
  Yagihara H, Terada Y, Sugimoto S, Hidaka F, Yamada O, Ono K, Washizu T, Ariizumi K, Bonkobara M.
- Journal Title
  
  Veterinary Journal (印刷中)
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Canine epidermal langerhans cells express alpha and gamma but not beta chains of high-affinity of IgE receptor2005
- Author(s)
  Makoto Bonkobara
- Journal Title
  
  Veterinary Research Communications 29
  
  Pages: 499-505
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380214
[Journal Article] Characterization of Kdap, a protein secreted by keratinocytes.2004
- Author(s)
  Tsuchida S, Bonkobara M, McMilan JR, Akiyama M, Yudate T, Aragane Y, Tezuka T, Shimizu H, Cruz PD Jr, Ariizutni K.
- Journal Title
  
  Journal of Investigative Dermatology 122
  
  Pages: 1225-1234
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Transcriptional regulation of dectin-2 promoter in transgenic mouse.2004
- Author(s)
  Bonkobara M, Yudate T, Yagihara H, Washizu T, Cruz PD Jr, Ariizumi K.
- Journal Title
  
  Journal of Veterinary Medical Science 66
  
  Pages: 1483-1489
- NAID
  10014192219
- Data Source
  KAKENHI-PROJECT-16780214
[Journal Article] Transcriptional regulation of dectin-2 promoter in transgenic mouse.2004
- Author(s)
  Bonkobara M
- Journal Title
  
  Journal of Veterinary Medical Science 66・12
  
  Pages: 1483-1489
- NAID
  10014192219
- Data Source
  KAKENHI-PROJECT-16580246
[Presentation] 犬の扁桃扁平上皮癌株化細胞におけるアファチニブの増殖抑制効果とその作用機序の解析2023
- Author(s)
  宮本良, 田村恭一, 盆子原誠
- Organizer
  獣医がん分子生物学研究会
- Data Source
  KAKENHI-PROJECT-22K06031
[Presentation] 分子標的治療薬のレビュー2022
- Author(s)
  盆子原誠
- Organizer
  第25回日本獣医がん学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03131
[Presentation] 犬の組織球性肉腫の発生・病態におけるApoptosis Inhibitor of Macrophage (AIM)の遺伝子変異による影響の検討2020
- Author(s)
  内田萌菜、米澤智洋、茂木朋貴、藤井渉、盆子原誠、原田慶、小林哲也、前田真吾、桃井康行
- Organizer
  第16回日本獣医内科学アカデミー
- Data Source
  KAKENHI-PROJECT-18H02340
[Presentation] Expression and genetic variation of apoptosis inhibitor of macrophage in canine histiocytic sarcoma2019
- Author(s)
  Mona UCHIDA, Kazuyuki UCHIDA, Hiroyuki TANI, Makoto BONKOBARA, Shingo MAEDA, Tomohiro YONEZAWA
- Organizer
  American College of Veterinary Internal Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02340
[Presentation] 犬骨髄細胞を用いた骨髄由来免疫抑制細胞の分化誘導2019
- Author(s)
  浅倉大輝、亀山仁美、田邉優、佐藤志織、菅沼亮太、田中文哉、山下諒、盆子原誠、田村恭一
- Organizer
  日本獣医臨床病理学会2019年大会
- Data Source
  KAKENHI-PROJECT-19H03131
[Presentation] Expression of apoptosis inhibitor of macrophage in canine histiocytic sarcoma and its relation to tumor malignancy2018
- Author(s)
  M. Uchida, Y. Matsumiya, M. Bonkobara, S. Maeda, T. Yonezawa
- Organizer
  Proceedings of the 18th biennial congress of the international society for animal clinical pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02340
[Presentation] 犬の肥満細胞腫におけるチロシンキナーゼ阻害剤耐性化機構2018
- Author(s)
  盆子原誠
- Organizer
  日本獣医内科アカデミー
- Invited
- Data Source
  KAKENHI-PROJECT-15H04601
[Presentation] ACNUにより治療した組織球性肉腫の犬の5例2017
- Author(s)
  飯島しずか、谷浩由輝、栗田晟那、宮本良、澤田治美、安田暁子、盆子原誠、田村恭一
- Organizer
  日本獣医臨床病理学会年次大会
- Data Source
  KAKENHI-PROJECT-15H04601
[Presentation] 担がん犬における末梢血中骨髄由来免疫抑制細胞の量的解析2016
- Author(s)
  宮本拓弥、藤原万里子、山本華以、山下諒、田村恭一、盆子原誠
- Organizer
  日本獣医臨床病理学会・年次大会
- Place of Presentation
  日本獣医生命科学大学（東京都武蔵野市）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-15H04601
[Presentation] 犬の悪性黒色腫4例に対するボルテゾミブの効果に関する検討2016
- Author(s)
  谷浩由輝、山本仁美、栗田晟那、宮本良、小野憲一朗、田村恭一、盆子原誠
- Organizer
  日本獣医臨床病理学会・年次大会
- Place of Presentation
  日本獣医生命科学大学（東京都武蔵野市）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-15H04601
[Presentation] 輸血副作用を惹起するネコAB式血液型を担うCMAH遺伝子の変異部位同定2015
- Author(s)
  左向　敏紀，小山　秀一，盆子原　誠，鷲巣　月美，落合　和彦，土田　修一，近江　俊徳
- Organizer
  第2回獣医生命科学会
- Place of Presentation
  日本獣医生命科学大学（武蔵野市，東京）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-25450454
[Presentation] Apoptosis inhibitor of macrophage (AIM)がイヌ組織球性肉腫株化細胞にもたらす影響2015
- Author(s)
  内田萌菜、米澤智洋、佐伯亘平、盆子原誠、前田真吾、松木直章
- Organizer
  獣医臨床病理学会2015年大会
- Place of Presentation
  日本獣医生命科学大学
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15H04590
[Presentation] 獣医療における分子標的薬の将来展望2015
- Author(s)
  盆子原誠
- Organizer
  獣医内科アカデミー
- Place of Presentation
  横浜
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] Genomic analysis of CMAH gene in a blood type B cat2015
- Author(s)
  Omi T, Taniguchi H, Ezoe S, Ochiai K, Sako T, Azakami D, Bonkobara M, Tsuchida S, Udagawa C.
- Organizer
  40th World Small Animal Veterinary Association Congress
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450454
[Presentation] B型ネコのCMAH遺伝子解析：新規変異遺伝子のcDNA単離とディプロタイプ2015
- Author(s)
  近江俊徳，宇田川智野，落合和彦，盆子原　誠，呰上大吾，左向敏紀，土田修一
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学（十和田市，青森）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-25450454
[Presentation] イマチニブ耐性を獲得した肥満細胞腫の犬の９例2015
- Author(s)
  守口昌悟、佐野文郁、林麻央、今井貴昌、小林正人、山下傑夫、小野憲一郎、田村恭一、盆子原誠、鷲巣月美
- Organizer
  獣医臨床病理学会
- Place of Presentation
  東京
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-26660243
[Presentation] 獣医療における分子標的薬の展望2015
- Author(s)
  盆子原誠
- Organizer
  獣医内科アカデミー（招待講演）
- Place of Presentation
  横浜
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26660243
[Presentation] イマチニブの登場と肥満細胞腫の治療2014
- Author(s)
  盆子原誠
- Organizer
  獣医内科アカデミー
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] In vitro Screening of Compounds led to the Identification of Dasatinib as a Potent Growth Inhibitor for Canine Histiocytic Sarcoma Cells2013
- Author(s)
  Keita ITO, Shiori KUROKI, Masato KOBAYASHI, Jason Wilson, Tsukimi WASHIZU, Makoto BONKOBARA
- Organizer
  WSAVA FASAVA 2013
- Place of Presentation
  ニュージーランド
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] Molecular basis of imatinib therapy in mast cell tumors2013
- Author(s)
  Makoto BONKOBARA
- Organizer
  WSAVA FASAVA 2013
- Place of Presentation
  ニュージーランド
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] イマチニブが奏効した犬の消化管間質腫瘍の1症例2013
- Author(s)
  小林正人、黒木詩織、伊藤慶太、安田暁子、澤田治、美小野憲一郎、鷲巣月美、盆子原誠
- Organizer
  獣医臨床病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] 分子標的薬による肥満細胞腫の治療2013
- Author(s)
  盆子原誠
- Organizer
  獣医臨床フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25660244
[Presentation] ここまで使えるフローサイトメトリー2013
- Author(s)
  盆子原誠
- Organizer
  獣医臨床病理学会2013年大会
- Data Source
  KAKENHI-PROJECT-25660244
[Presentation] Molecular-targeting therapy with imatinib in mast cell tumors2013
- Author(s)
  Makoto BONKOBARA
- Organizer
  WSAVA FASAVA 2013
- Place of Presentation
  ニュージーランド
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] 犬組織球性肉腫に対するダサチニブの増殖抑制効果に関する研究2012
- Author(s)
  伊藤慶太、池谷早代、竹下恭平、黒木詩織、小林正人、盆子原誠、鷲巣月美
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] 腫瘍の遺伝子検査～犬と猫の肥満細胞腫～2012
- Author(s)
  盆子原誠
- Organizer
  日本獣医内科学アカデミー/日本獣医臨床病理学会
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] 犬の悪性黒色腫細胞に対するBortezomibの増殖抑制効果に関する研究2012
- Author(s)
  手塚雅典、中川朋子、廣井輝代、山本仁美、小澤佑太、伊藤慶太、黒木詩織、小林正人、盆子原誠、鷲巣月美
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] イヌ乳腺腫瘍関連遺伝子BRCA2のBRC repeat 3に存在するSNPsの頻度および機能に及ぼす影響の検討2012
- Author(s)
  落合和彦、塩入弓絵、染田沙織、大澤有加、宇田川智野、森松正美、吉川泰永、盆子原誠、土田修一、近江俊徳
- Organizer
  第155回日本獣医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] イヌUCP2およびUCP3 : SNPディスカバリーと2犬種のSNPジェノタイピング2012
- Author(s)
  宇田川智野、多田尚美、青木博史、盆子原誠、土田修一、落合和彦、石岡克己、鄭英和、近江俊徳
- Organizer
  第155回日本獣医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] Molecular targeted therapy with imatinib in canine and feline mast cell tumor2012
- Author(s)
  Makoto BONKOBARA
- Organizer
  2012 RIVM International Symposium
- Place of Presentation
  韓国
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] 犬のイマチニブ耐性肥満細胞腫細胞株の樹立と耐性化機構の解析2012
- Author(s)
  田中優、小堤友香梨、守谷友加里、上原裕司、小林正人、杉崎修、伊藤慶太、黒木詩織、盆子原誠、鷲巣月美
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-24380173
[Presentation] 猫の肥満細胞腫の現状と分子標的療法2011
- Author(s)
  盆子原誠
- Organizer
  West Japan Veterinary Forum
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] 犬と猫の肥満細胞腫に対する分子標的療法の展開～c-kit変異とイマチニブの効果～2011
- Author(s)
  盆子原誠
- Organizer
  日本獣医内科学アカデミー/日本獣医臨床病理学会/日本獣医皮膚科学会
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] 分子生物学から見る肥満細胞腫2011
- Author(s)
  盆子原誠
- Organizer
  West Japan Veterinary Forum
- Place of Presentation
  大阪
- Year and Date
  2011-06-19
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] 犬の腫瘍の新しい診断・治療戦略～肥満細胞腫2011
- Author(s)
  盆子原誠
- Organizer
  予防動物医学研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] 犬の腫瘍の新しい診断・治療戦略～肥満細胞腫～2011
- Author(s)
  盆子原誠
- Organizer
  予防動物医学研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] イマチニブが奏功したc-kitエクソン8に重複配列挿入変異を有する腸管型肥満細胞腫の犬の1例2011
- Author(s)
  小林正人・杉崎修、小堤友香梨・田中優・守谷友加里・石井典子・伊藤慶太・盆子原誠・小野憲一郎・鷲巣月美
- Organizer
  日本獣医内科学アカデミー/日本獣医臨床病理学会/日本獣医皮膚科学会
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] イマチニブが奏功したc-kitエクソン9に点変異を有する肥満細胞腫の犬の1例2010
- Author(s)
  杉崎修・小林正人・小堤友香梨・田中優・守谷友加里・石井典子・山田理・礒谷真由・伊藤慶太・盆子原誠・小野憲一郎・鷲巣月美
- Organizer
  日本獣医臨床病理学会大阪シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] 猫の肥満細胞腫における新規c-kit遺伝子変異の同定とイマチニブによるKITリン酸化抑制の検討2010
- Author(s)
  石井典子・杉崎修・小林正人・山田理・西上達也・吉田俊一・磯谷真弓・伊藤慶太・盆子原誠・小野憲一郎・鷲巣月美
- Organizer
  第150回日本獣医学会
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] 犬の悪性黒色腫株化細胞に対する分子標的薬の増殖抑制効果に関する研究2010
- Author(s)
  岩田泰介・黒木哲也・森光平・小澤佑太・手塚雅典・中川朋子・廣井輝代・伊藤慶太・盆子原誠・小野憲一郎・鷲巣月美
- Organizer
  第150回日本獣医学会
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] イマチニブが奏功したc-kitエクソン9に点変異を有する肥満細胞腫の犬の1例2010
- Author(s)
  小林正人・杉崎修、小堤友香梨・田中優・守谷友加里・石井典子・山田理・礒谷真由・伊藤慶太・盆子原誠、小野憲一郎・鷲巣月美
- Organizer
  第150回日本獣医学会
- Data Source
  KAKENHI-PROJECT-21580395
[Presentation] ネコAB式血液型における抗原出現頻度とDNAタイピング
- Author(s)
  宇田川智野、片桐紗貴子、橘　早紀、蒔田莉菜、古関純也、江添沙耶谷口ひろみ、落合和彦、盆子原　誠、土田修一、近江俊徳
- Organizer
  日本DNA多型学会第22回学術集会
- Place of Presentation
  仙台市戦災復興記念館(宮城県）
- Data Source
  KAKENHI-PROJECT-25450454
[Presentation] Phenotypic and molecular genetic analysis of the cat AB blood group system
- Author(s)
  Toshinori Omi、Chihiro Udagawa、Rina Makita、Junya Furuseki、 Kazuhiko Ochiai、Daigo Azakami、Toshinori Sako、Makoto Bonkobara、Shuichi Tsuchida、Shigenori Ikemoto
- Organizer
  34th International Society for Animal Genetics Conference
- Place of Presentation
  Xi'an, China
- Year and Date
  2014-07-27 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25450454
[Presentation] Genomic analysis of CMAH gene in a blood type B cat
- Author(s)
  Toshinori Omi、Hiromi Taniguchi、Saya Ezoe、 Kazuhiko Ochiai、Toshinori Sako、Daigo Azakami、Makoto Bonkobara、Shuichi Tsuchida、Chihiro Udagawa
- Organizer
  40th World Small Animal Veterinary Association Congress
- Place of Presentation
  Bangkok,Thailand
- Year and Date
  2015-05-15 – 2015-05-20
- Data Source
  KAKENHI-PROJECT-25450454
[Presentation] ゲノムワイド関連解析によるイヌ赤血球型（DEA1.1）責任候補遺伝子探索の試み
- Author(s)
  近江俊徳、宇田川智野、呰上大吾、浅野潤三、落合和彦、盆子原誠、土田修一
- Organizer
  日本獣医臨床病理学会2014年大会．
- Place of Presentation
  東京
- Year and Date
  2014-05-31 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-25450454
[Presentation] ネコのAB式血液型における各抗原の出現頻度について
- Author(s)
  蒔田莉菜、古関純也、宇田川智野、鄭　英和、落合和彦、呰上大吾、盆子原　誠、土田修一、近江俊徳
- Organizer
  第44回日本比較臨床医学会
- Place of Presentation
  自然科学研究機構（愛知県）
- Data Source
  KAKENHI-PROJECT-25450454

1. TANAKA Yoshikazu (50291159)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. ONO Kenichiro (50111480)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
3. AZAKAMI DAIGO (80453934)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. TOSHIRO Arai (70184257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. WASHIZU Tsukimi (20191736)

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6. TAZAKI Hiroyuki (80231405)

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7. OMI Toshinori (40296091)

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# of Collaborated Products: 12 results
8. Michishita Masaki (50434147)

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# of Collaborated Products: 5 results
9. MATSUKI Naoaki (40251417)

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# of Collaborated Products: 4 results
10. Yonezawa Tomohiro (10433715)

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# of Collaborated Products: 4 results
11. 佐々木崇 (50723897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. TOMIHARI Mizuki (00552754)

# of Collaborated Projects: 1 results

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13. SHIMADA Takashi (20125074)

# of Collaborated Projects: 1 results

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14. TUCHIDA Shuichi (20217326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
15. NAKAGAWA TAKAYUKI (40447363)

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16. ICHIKAWA HITOSHI (30201924)

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17. YOSHIMURA HISASHI (70645241)

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18. MATSUMOTO Yoshitsugu (00173922)

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19. SHIMADA Terumasa (00264812)

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20. KIMURA Nobuhiro (00350174)

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21. TAMURA KYOICHI (00722282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
22. 落合和彦 (30550488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. 石渡俊行 (90203041)

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24. 角田茂 (80345032)

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25. 前田真吾 (80755546)

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# of Collaborated Products: 3 results
26. NAKAHIRA REI

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27. ARIIZUMI KIYOSHI

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28. YASUDA AKIKO

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29. SHIGIHARA KAE

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30. FUJINO Yasuhito

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31. NAKAO Nobuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 鷲巣月美

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
33. 根本有希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

BONKOBARA Makoto 盆子原 誠

盆子原 誠 ボンコバラ マコト

MAKOTO Bonkobara 盆子 原誠

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犬TP53変異扁平上皮癌における「未成熟終止コドン読み飛ばし」に基づく治療戦略の創出Principal Investigator

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Development of a novel therapeutic strategy for KIT mutation-positive canine mast cell tumor using molecular gluePrincipal Investigator

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Analysis of diversity in tyrosine kinase inhibitor resistance in mast cell tumors toward establishment of individualized therapyPrincipal Investigator

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Studies on the mechanisms and therapeutic approach for resistance of tyrosine kinase inhibitors in mast cell tumourPrincipal Investigator

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Establishment of detection system for canine circulating tumor cellPrincipal Investigator

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Changes of DNA profile in canine granular tumor cells transformed to melanoma cellsPrincipal Investigator

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Analysis of oncogene addiction and development of molecular-targeted therapy for small animal tumoursPrincipal Investigator

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Analysis of aberrantly activated receptor tyrosine kinase and development of molecular targeting therapy in small animals with malignancies.Principal Investigator

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Study for inhibitory regulation of auto reactive T-cell by DC-HILPrincipal Investigator

BONKOBARA Makoto 盆子原誠

盆子原誠ボンコバラマコト

MAKOTO Bonkobara 盆子原誠