Seki Naohiko 関直彦

… Alternative Names

Researcher Number	50345013
Other IDs
Affiliation (Current)	2021: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2021: 千葉大学, 医学(系)研究科(研究院), 准教授 2015 – 2019: 千葉大学, 大学院医学研究院, 准教授 2011 – 2016: 千葉大学, 医学(系)研究科(研究院), 准教授 2013: 千葉大学, 大学院医学研究院, 准教授 2007 – 2012: Chiba University, Graduate School, Dept Genome Sci, Assoc Prof … More
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related / Thoracic surgery Except Principal Investigator Urology / Otorhinolaryngology / Thoracic surgery / Surgical dentistry / Respiratory organ internal medicine / Surgical dentistry / Basic Section 53030:Respiratory medicine-related … More
Keywords	Principal Investigator マイクロRNA / 癌抑制遺伝子 / 頭頸部扁平上皮癌 / 機能性RNA / 発現プロファイル / 癌抑制型マイクロRNA / 治療抵抗性 / 癌 / 機能性核酸 / 頭頚部扁平上皮癌 … More Except Principal Investigator マイクロRNA / microRNA / マイクロアレイ / 癌抑制遺伝子 / 膀胱癌 / 前立腺癌 / マイクロＲＮＡ / 頭頸部扁平上皮癌 / ゲノム / 肺癌 / 癌 / 発現プロファイル / 去勢抵抗性 / 腎細胞癌 / 予後 / cDNA microarray / maspin / stathmin / 治療抵抗性 / DNAチップ / 口腔扁平上皮癌 / 遺伝子発現プロファイリング / cDNA / がん抑制遺伝子 / NBI / 遺伝子解析 / 浸潤 / 頭頸部癌 / 扁平上皮癌 / ナノミセル / 去勢抵抗性前立腺癌 / 転移 / 口腔癌 / 癌遺伝子 / オルガノイド / 喫煙 / 外科 / 尿路上皮癌 / 腫瘍マーカー / 蛍光電子内視鏡 / 下咽頭癌 / 遺伝子 / がん / 癌抑制 / 転移抑制 / 癌抑制型マイクロRNA / セツキシマブ / 分子標的薬 / 化学療法 / DNA microarray / oral squamous cell carcinoma / 腺癌 / microarray / gene expression / mouse / bone formation / fracture repair / periostin / knock-out mouse / TNF-alpha / cDNAマイクロアレイ / マイクロアレイ解析 / 唾液腺癌 / oral cancer / microarray analysis / salivary gland tumor / Lung cancer / Microarray / Prognosis / 2D-DIGE / MALDI-TOF / MS / peptide mass fingerprinting / COPD / VEGF / 放射線感受性 / SKP2 / CKS1 / p16INK4a / p14ARF / SNP / MMP-1 / siRNA / 抗がん剤 / PET / 細胞外マトリックス / 腎癌 / 薬剤耐性 / 核酸 / 小細胞肺癌 / 機能性RNA / 分子細胞呼吸器学 / エクソソーム / 発癌抵抗性 / 発癌予防法 / 飲酒 / 唾液腺 / 呼吸器外科学 / -マイクロアレイ / FSCN1 / 診断マーカー / 超拡大内視鏡 / 気管支異形成 / 蛍光電子視鏡 / 神経ペプチド / ニューロテンシン / アポトーシス / 標的遺伝子解析 / PC3 / 細胞増殖 / 標的遺伝子 / 増殖 / 発癌 / 上顎洞癌 / miR-874 / HDAC1 / 上顎癌 / NKT細胞 / 癌免疫療法 / 悪性黒色腫 / 細胞障害性T細胞 / アジュバント療法 / 先進医療 / アジュバンド療法 / 膀胱がん / miR-504 / CDK6 / ｍｉｃｒｏＲＮＡ / ゲノムシークエンス / 治療効果予測因子 / 上皮成長因子受容体 / EGFR / 分子ネットワーク / 薬剤感受性 / chemotherapy / drug resistance / 悪性度評価 / 悪牲度評価 / 悪性度評価法 / diagnosis / risk for carcinogenesis / risk for micrometastasis / risk for malignant grade / 骨折治癒 / periostin(ペリオスチン) / in situ hybridization / Northern blotting / RT-PCR / 仮骨 / 遺伝子機能評価 / 庸平上皮癌 / 遺伝子クローニング / squamous cell carcinoma / pleomorphic adenoma / 胃癌 / 微小転移 / センチネルリンパ節生検 / LAMP法遺伝子増幅 / 微小転移診断 / GASTRIC CANCER / MICROMETASTASIS / SENTINEL LYMPH NODE / LAMP AMPLIFICATION / cDNA MICROARRAY / 腺様嚢胞癌 / 線様嚢胞癌 / 唾液腺腫瘍 / adenoid cystic carcinoma / タンパク発現プロファイリ / タンパク発現プロファイリング / _2D-DIGE / petide mass fingerprinting / profiling of protein expression / 血管内皮前駆細胞 / 肺気腫 / 骨髄 / マウス / Emphysema / Smoking / Endothelial Progenitor Cells / Bone Marrow / Mouse / 消化器扁平上皮癌 / 遺伝子発現解析 / human squamous cell carcinoma / radiosensitivity / gene expression profile / 浸潤性 / DNAメチル化 / DNAマイクロアレイ / クラスター解析 / 再発 / Bladder cancer / invasiveness / prognosis / DNA methylation / 変形性膝関節症 / ホームエクササイズ / 間接裂隙 / 運動療法 / 有効性 / 自然経過 / knee osteoarethritis / home-base exercise / joint space width / 遺伝子治療 / Radiation sensitivity / Genetherapy / テーラーメイド治療 / tailor-made treatment / シスプラチン / 遺伝子発現 / 放射線治療 / マルチモダリティー治療 / 細胞周期 / 放射線 / Cisplatin / Gene expression / Radiotherapy / Multi-modality therapy / Cell cycle / 高解像度気管支ビデオスコープ / 気管支dysplasia / AFI / high resolution bronchovideoscopy / bronchial dysplasia / MET / 低酸素 / 泌尿器癌 / microＲＮＡ / スニチニブ耐性 / miRNA-199 / miRNA-223 / 治療標的型マイクロRNA / シグナル伝達 / 核酸医薬 / DONSON / 次世代シーケンサー / ホルモン感受性 / CRPC / 次世代シークエンサー / ネットワーク / 網羅的解析 / miR-99a-3p / 特発性肺線維症 / 肺線維症 / Notch / heterogeneity / 3Ｄ培養 / 癌幹細胞 / 肺扁平上皮癌 / ドラッグリポジショニング / 間質性肺炎合併肺癌 / トリプルネガティブ乳癌 / プロファイル / 大腸癌 / 食道扁平上皮癌 Less

頭頸部癌・転写調節領域を指標とした薬剤耐性に関与する機能性RNA分子の探索Principal InvestigatorOngoing
- Principal Investigator
  
  関直彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
マイクロRNAを起点とした肺扁平上皮癌に関する分子経路と新規治療法の探索研究Ongoing
- Principal Investigator
  
  内田章文
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kagoshima University
小細胞肺癌の機能性RNA統合解析に基づくドラッグ・リポジショニングの考案Ongoing
- Principal Investigator
  
  水野圭子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kagoshima University
機能性RNA統合理解に基づく間質性肺炎合併肺癌の分子経路探索と新規治療法の開発Ongoing
- Principal Investigator
  
  眞田宏樹
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kagoshima University
Elucidation of therapeutic target molecular pathway by understanding tripli negative breast cancer and functional RNA integrationOngoing
- Principal Investigator
  
  戸田洋子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kagoshima University
Diagnostic and identification of therapeutic target molecules based on functional RNA network search in colorectal cancer.
- Principal Investigator
  
  吉満工平
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kagoshima University
Elucidation of molecular pathogenesis of esophageal squamous cell carcinoma based on comprehensive functional RNA analysisOngoing
- Principal Investigator
  
  和田真澄
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kagoshima University
機能性RNAを起点とした治療抵抗性頭頸部扁平上皮癌のドラッグリポジション戦略Ongoing
- Principal Investigator
  
  吉川直子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
食道扁平上皮癌オルガノイド・マイクロRNA解析による治療抵抗性分子経路の解明
- Principal Investigator
  
  下之薗将貴
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kagoshima University
消化器癌個別化治療にむけた3D培養と共培養を用いた癌組織不均一性の基礎研究Ongoing
- Principal Investigator
  
  喜多芳昭
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kagoshima University
機能性RNA解析に基づく頭頚部扁平上皮癌治療抵抗性獲得機序の探索Principal InvestigatorOngoing
- Principal Investigator
  
  関直彦
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
浸潤性膀胱癌・オルガノイド培養系を用いた機能性RNA解析と術前化学療法の最適化
- Principal Investigator
  
  菅原翔
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Chiba University
Development of innovative therapy for treatment-resistant small cell lung cancer based on functional RNA network analysis
- Principal Investigator
  
  KUMAMOTO TOMOHIRO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kagoshima University
Elucidate the functional RNA network in castration-resistant prostate cancer and therapeutic approach
- Principal Investigator
  
  Kojima Satoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Teikyo University
Identification of drug-resistance related RNA networks in head and neck squamous cell carcinoma cells
- Principal Investigator
  
  HANAZAWA TOYOYUKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Elucidation of the microRNA-mediated RNA networks in castration resistant prostate cancer and development of innovative treatments
- Principal Investigator
  
  Ichikawa Tomohiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Chiba University
Exploring molecular network of functional nucleic acid and developing therapeutic innovations in drug-resistant renal cell carcinoma
- Principal Investigator
  
  NAKAGAWA Masayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Development of the innovative treatment based on the search of microRNA blocking growth signals in urothelial carcinoma
- Principal Investigator
  
  YOSHINO Hirofumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Identification of activated molecular pathways involved in treatment-resistant head and neck squamous cell carcinoma
- Principal Investigator
  
  KIKKAWA NAOKO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Development of nuclear acid medicine by using tumor suppressive microRNA conjugated with high molecular nano-micelle
- Principal Investigator
  
  TATARANO Shuichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Investigation of the common RNA networks in lung cancer and idiopathic pulmonary fibrosis for the new strategy of the diseases.
- Principal Investigator
  
  MATAKI Hiroko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kagoshima University
Elucidation of extracellular matrix molecular pathway regulated by metastasis-suppressing microRNAs in prostate cancer.
- Principal Investigator
  
  KATO MAYUKO
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Chiba University
Elucidation of the extracellular matrix signal mechanism controled by tumor suppressor microRNAs in head and neck cancer
- Principal Investigator
  
  Ichiro Fukumoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Southen Tohoku Research Institute for Neuroscience
  Chiba University
Development of novel therapeutic strategies in head and neck squamous cell carcinoma based on microRNA-mediated cancer pathwaysPrincipal Investigator
- Principal Investigator
  
  SEKI NAOHIKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Development of novel nucleic acid treatment through nano-micelles delivering tumor suppressive microRNA in bladder cancer
- Principal Investigator
  
  ENOKIDA Hideki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Study for elucidating tumor suppressive microRNA that has anti proliferation and prevent metastasis by using metastasis model mouse in bladder cancer
- Principal Investigator
  
  ITESAKO Toshihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Analysis of functional RNA networks and investigation of their target genes in castration-resistant prostate cancer (CRPC).
- Principal Investigator
  
  Kojima Satoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Teikyo University
Investigation into the predictor of cetuximab effect based on microRNA in head and neck squamous cell carcinoma
- Principal Investigator
  
  Hanazawa Toyoyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Investigation of hypoxia resistance in renal cell carcinoma based on functional RNA network analyses
- Principal Investigator
  
  Chiyomaru Takeshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Clarification of microRNA functional networks and development of novel tools for diagnosis and treatment of castration-resistant prostate cancer
- Principal Investigator
  
  Ichikawa Tomohiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Chiba University
Development of novel tumor markers for renal cell carcinoma by evaluating small nuclear acid in blood
- Principal Investigator
  
  tatarano shuichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kagoshima University
Order made therapy for bladder cancer by investigating functional RNAs associated molecular networks
- Principal Investigator
  
  Nakagawa Masayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Development of new therapeutic strategies of hypopharyngeal cancer based on the RNA network analysis
- Principal Investigator
  
  KIKKAWA Naoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Development of adjuvant therapy for head and neck cancer by activation of NKT cells via nasal mucosa
- Principal Investigator
  
  Okamoto Yoshitaka
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Identification of tumor-suppressive microRNAs regulating metastatic pathways in HNSCCPrincipal Investigator
- Principal Investigator
  
  SEKI Naohiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Analysis of gene regulation networks controlled by microRNA in castration resistant prostate cancer
- Principal Investigator
  
  KOJIMA Satoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Teikyo University
Identification of tumor suppressive nucleic acid medicine in maxillary sinus squamous cell carcionma
- Principal Investigator
  
  HANAZAWA Toyoyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Anti-proliferative miRNA expression in squamous cell carcinoma of the lung: Pursue for the common therapeutic targets of the tobacco-related cancer
- Principal Investigator
  
  MORIYA Yasumitsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba Cancer Center (Research Institute)
  Chiba University
Identification of differentially expressed microRNAs in head and neck squamous cell carcinoma based on microRNA expression signaturePrincipal Investigator
- Principal Investigator
  
  SEKI Naohiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Analysis of function and the target genes of micro-RNAs in prostate cancer
- Principal Investigator
  
  KOJIMA Satoko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Teikyo University
Developing new treatment modalities of urothelial carcinoma through regulating microRNA expression
- Principal Investigator
  
  NAKAGAWA Masayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
新しい超拡大内視鏡システムとマイクロアレイによる気管支異形成遺伝子発現の解析
- Principal Investigator
  
  渋谷潔
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba University
Role of Neuropeptide Signals Induced Metastasis of Hypopharyngeal Cancer
- Principal Investigator
  
  HANAZAWA Toyoyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Prediction of lymph node metastasis by gene expression profiling in patients with primary resected lung cancer
- Principal Investigator
  
  IYODA Akira
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kitasato University
  Chiba University
Screening and validation of target molecules involved in mechanism of multi-modality therapy
- Principal Investigator
  
  TAKIGUCHI Yuichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
The treatment strategy of bronchial dysplasia using a novel autofluorescence imaging bronchovideoscope system and microarray
- Principal Investigator
  
  SHIBUYA Kiyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba University
Efficacy and natural course of therapeutic exercise for patients with knee osteoarthritis : Analysis by SNP
- Principal Investigator
  
  KUROSAWA Hisashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
The development of the novel genetherapy to enhance the radiation sensitivity.
- Principal Investigator
  
  NIMURA Yoshinori
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Chiba Cancer Center (Research Institute)
The strategy based on gene expression profiling using microarray for tailor-made treatment in patients with lung cancer
- Principal Investigator
  
  IYODA Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba University
Development of cancer immunotherapy using cancer-specific peptide based on genome analysisPrincipal Investigator
- Principal Investigator
  
  SEKI Naohiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba University
Identification of proteins associated with oral cancer by global proteomic approach.
- Principal Investigator
  
  TANZAWA Hideki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Role of Endothelial progenitor Cell in the pathogenesis of COPD
- Principal Investigator
  
  KASAHARA Yasunori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Construction of in-house cDNA microarrays for identifying radiotherapeutic molecular markers in human aquamous cell carcinoma
- Principal Investigator
  
  UZAWA Katsuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Chiba University
Establishment of prediction system for the prognosis of patients with bladder cancer
- Principal Investigator
  
  NAKAGAWA Masayuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
唾液腺組織のcDNAライブラリー作成と唾液腺疾患用DNAチップの開発作製
- Principal Investigator
  
  丹沢秀樹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Search for oral cancer specific genes and molecular cloning using in-house cDNA microaray
- Principal Investigator
  
  SHIBA Masashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
ESTABLISHMENT OF AN INTRA-OPERATIVE TECHNIQUE FOE DETECTION OF MICROMETASTASES IN GASTRIC CANCER SURGERY USING LAMP GENE AMPLIFICATION.
- Principal Investigator
  
  HAYASHI Hedeki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Gene expression profiling in primary lung cancer with oligonucleotide microarray.
- Principal Investigator
  
  IYODA Akira
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba University
Gene profiling in adenoid cystic carcinoma cells using in-house cDNA microaray
- Principal Investigator
  
  YOKOE Hidetaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
独自に開発したDNAチップを用いた発癌因子抵抗性評価および発癌予防法の開発
- Principal Investigator
  
  宮川昌久
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Development of the method to select the most effective anti-cancer chemotherapy using in-house cDNA microarray
- Principal Investigator
  
  UZAWA Katsuhiro, 宮川昌久
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Development of the diagnostic method to evaluate the risks for carcinogenesis, micro-metastasis, and malignant grade of oral cancer using in-house cDNA microarray
- Principal Investigator
  
  TANZAWA Hideki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Identification of novel genes regulating fracture healing and their functional analyzes
- Principal Investigator
  
  YAMAZAKI Masashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University

[Journal Article] Regulation of Oncogenic Targets by miR-99a-3p (Passenger Strand of miR-99a-Duplex) in Head and Neck Squamous Cell Carcinoma.2020
- Author(s)
  Okada Reona、Koshizuka Keiichi、Yamada Yasutaka、Moriya Shogo、Kikkawa Naoko、Kinoshita Takashi、Hanazawa Toyoyuki、Seki Naohiko
- Journal Title
  
  Cells.
  
  Volume: 8 Pages: 1535-1535
- DOI
  10.3390/cells8121535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-19K18795, KAKENHI-PROJECT-17K11375
[Journal Article] Regulation of aberrantly expressed SERPINH1 by antitumor miR-148a-5p inhibits cancer cell aggressiveness in gastric cancer.2020
- Author(s)
  Kawagoe K, Wada M, Idichi T, Okada R, Yamada Y, Moriya S, Okubo K, Matsushita D, Arigami T, Kurahara H, Maemura K, Natsugoe S, Seki N.
- Journal Title
  
  J Hum Genet
  
  Volume: -
- DOI
  10.1038/s10038-020-0746-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08687
[Journal Article] Role of pre-miR-532 (miR-532-5p and miR-532-3p) in regulation of gene expression and molecular pathogenesis in renal cell carcinoma.2019
- Author(s)
  Yamada Y, Arai T, Kato M, Kojima S, Sakamoto S, Komiya A, Naya Y, Ichikawa T, Seki N.
- Journal Title
  
  American Journal of Clinical and Experimental Urology
  
  Volume: 7 Pages: 11-30
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05462
[Journal Article] Gene regulation by antitumor miR-204-5p in pancreatic ductal adenocarcinoma: The clinical significance of direct RACGAP1 regulation.2019
- Author(s)
  Khalid M, Idichi T, Seki N, Wada M, Yamada Y, Fukuhisa H, Toda H, Kita Y, Kawasaki Y, Tanoue K, Kurahara H, Mataki Y, Maemura K, Natsugoe S.
- Journal Title
  
  Cancers
  
  Volume: 11 Pages: 327-327
- DOI
  10.3390/cancers11030327
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08687, KAKENHI-PROJECT-18K16322, KAKENHI-PROJECT-16K19945, KAKENHI-PROJECT-18K08626, KAKENHI-PROJECT-18K15219
[Journal Article] Gene regulation by antitumor miR-130b-5p in pancreatic ductal adenocarcinoma: the clinical significance of oncogenic EPS82019
- Author(s)
  Fukuhisa H, Seki N, Idichi T, Kurahara H, Yamada Y, Toda H, Kita Y, Kawasaki Y, Tanoue K, Mataki Y, Maemura K, Natsugoe S.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: - Pages: 521-534
- DOI
  10.1038/s10038-019-0584-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08687, KAKENHI-PROJECT-18K16322, KAKENHI-PROJECT-16K19945, KAKENHI-PROJECT-18K08626, KAKENHI-PROJECT-18K15219
[Journal Article] Pirin: a potential novel therapeutic target for castration-resistant prostate cancer regulated by miR-455-5p.2019
- Author(s)
  Arai Takayuki、Kojima Satoko、Yamada Yasutaka、Sugawara Sho、Kato Mayuko、Yamazaki Kazuto、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  Mol Oncol
  
  Volume: 13 Pages: 322-337
- DOI
  10.1002/1878-0261.12405
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-18K16724, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K11160
[Journal Article] Molecular pathogenesis of esophageal squamous cell carcinoma: Identification of the antitumor effects of miR?145?3p on gene regulation2019
- Author(s)
  Shimonosono M, Idichi T, Seki N, Yamada Y, Arai T, Arigami T, Sasaki K, Omoto I, Uchikado Y, Kita Y, Kurahara H, Maemura K, Natsugoe S.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 54 Pages: 637-688
- DOI
  10.3892/ijo.2018.4657
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08687, KAKENHI-PROJECT-18K16322, KAKENHI-PROJECT-16K10510, KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-17H04285
[Journal Article] Involvement of dual-strand of the miR-144 duplex and their targets in the pathogenesis of lung squamous cell carcinoma2019
- Author(s)
  Uchida Akifumi、Seki Naohiko、Mizuno Keiko、Misono Shunsuke、Yamada Yasutaka、Kikkawa Naoko、Sanada Hiroki、Kumamoto Tomohiro、Suetsugu Takayuki、Inoue Hiromasa
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 420-432
- DOI
  10.1111/cas.13853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-18K09338
[Journal Article] Role of pre-miR-532 (miR-532-5p and miR-532-3p) in regulation of gene expression and molecular pathogenesis in renal cell carcinoma2019
- Author(s)
  Yasutaka Yamada,Takayuki Arai, Mayuko Kato,Satoko Kojima, Shinichi Sakamoto, Akira Komiya, Yukio Naya, Tomohiko Ichikawa, and Naohiko Seki
- Journal Title
  
  Am J Clin Exp Urol
  
  Volume: 7 Pages: 11-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11160
[Journal Article] Molecular Pathogenesis of Interstitial Cystitis Based on microRNA Expression Signature: miR-320 Family-Regulated Molecular Pathways and Targets2019
- Author(s)
  Arai T, Fuse M, Goto Y, Kaga K, Kurozumi A, Yamada Y, Sugawara S, Okato A, Ichikawa T, Yamanishi T, Seki N.
- Journal Title
  
  J Hum Genet.
  
  Volume: 印刷中 Pages: 543-554
- DOI
  10.1038/s10038-018-0419-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16779, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
[Journal Article] Regulation of KIF2A by Antitumor miR-451a Inhibits Cancer Cell Aggressiveness Features in Lung Squamous Cell Carcinoma2019
- Author(s)
  Uchida Akifumi、Seki Naohiko、Mizuno Keiko、Yamada Yasutaka、Misono Shunsuke、Sanada Hiroki、Kikkawa Naoko、Kumamoto Tomohiro、Suetsugu Takayuki、Inoue Hiromasa
- Journal Title
  
  Cancers
  
  Volume: 11 Pages: 258-258
- DOI
  10.3390/cancers11020258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-18K09338
[Journal Article] RNA‐sequence‐based microRNA expression signature in breast cancer: tumor‐suppressive miR‐101‐5p regulates molecular pathogenesis2019
- Author(s)
  Toda Hiroko、Seki Naohiko、Kurozumi Sasagu、Shinden Yoshiaki、Yamada Yasutaka、Nohata Nijiro、Moriya Shogo、Idichi Tetsuya、Maemura Kosei、Fujii Takaaki、Horiguchi Jun、Kijima Yuko、Natsugoe Shoji
- Journal Title
  
  Molecular Oncology
  
  Volume: 14 Pages: 426-446
- DOI
  10.1002/1878-0261.12602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09049, KAKENHI-PROJECT-18K16322
[Journal Article] Micro ‐ribonucleic acid expression signature of metastatic castration‐resistant prostate cancer: Regulation of NCAPH by antitumor miR‐199a/b‐3p2019
- Author(s)
  Arai T, Kojima S, Yamada Y, Sugawara S, Kato M, Yamazaki K, Naya Y, Ichikawa T, Seki N.
- Journal Title
  
  Int J Urol
  
  Volume: 26 Pages: 506-520
- DOI
  10.1111/iju.13911
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16724, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-18K16685
[Journal Article] Molecular Pathogenesis of Gene Regulation by the miR-150 Duplex: miR-150-3p Regulates TNS4 in Lung Adenocarcinoma2019
- Author(s)
  Misono Shunsuke、Seki Naohiko、Mizuno Keiko、Yamada Yasutaka、Uchida Akifumi、Sanada Hiroki、Moriya Shogo、Kikkawa Naoko、Kumamoto Tomohiro、Suetsugu Takayuki、Inoue Hiromasa
- Journal Title
  
  Cancers
  
  Volume: 11 Pages: 601-601
- DOI
  10.3390/cancers11050601
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09338
[Journal Article] Passenger strand of miR-145-3p acts as a tumor-suppressor by targeting MYO1B in head and neck squamous cell carcinoma2018
- Author(s)
  Yamada Y, Koshizuka K, Hanazawa T, Kikkawa N, Okato A, Idichi T, Arai T, Sugawara S, Katada K, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol
  
  Volume: 52 Pages: 166-178
- DOI
  10.3892/ijo.2017.4190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229, KAKENHI-PROJECT-18K09338
[Journal Article] Impact of novel oncogenic pathways regulated by antitumor miR-451a in renal cell carcinoma2018
- Author(s)
  Yamada Yasutaka、Arai Takayuki、Sugawara Sho、Okato Atsushi、Kato Mayuko、Kojima Satoko、Yamazaki Kazuto、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Pages: 1239-1253
- DOI
  10.1111/cas.13526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-17K16778
[Journal Article] Anti-tumor roles of both strands of the miR-455 duplex: their targets SKA1 and SKA3 are involved in the pathogenesis of renal cell carcinoma.2018
- Author(s)
  Yamada, Y. Arai, T. Kojima, S. Sugawara, S. Kato, M. Okato, A. Yamazaki, K. Naya, Y. Ichikawa, T. Seki, N.
- Journal Title
  
  Oncotarget
  
  Volume: 9 (42) Pages: 26638-26658
- DOI
  10.18632/oncotarget.25410
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-18K16723, KAKENHI-PROJECT-16H05462
[Journal Article] Dual strands of the miR-223 duplex (miR-223-5p and miR-223-3p) inhibit cancer cell aggressiveness: targeted genes are involved in bladder cancer pathogenesis2018
- Author(s)
  Sugawara Sho、Yamada Yasutaka、Arai Takayuki、Okato Atsushi、Idichi Tetsuya、Kato Mayuko、Koshizuka Keiichi、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 印刷中 Pages: 657-668
- DOI
  10.1038/s10038-018-0437-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
[Journal Article] Inhibition of integrin beta1-mediated oncogenic signalling by the antitumor microRNA-29 family in head and neck squamous cell carcinoma2018
- Author(s)
  Koshizuka Keiichi、Kikkawa Naoko、Hanazawa Toyoyuki、Yamada Yasutaka、Okato Atsushi、Arai Takayuki、Katada Koji、Okamoto Yoshitaka、Seki Naohiko
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 3663-3676
- DOI
  10.18632/oncotarget.23194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
[Journal Article] Regulation of NCAPG by miR-99a-3p (passenger strand) inhibits cancer cell aggressiveness and is involved in CRPC2018
- Author(s)
  Arai, T. Okato, A. Yamada, Y. Sugawara, S. Kurozumi, A. Kojima, S. Yamazaki, K. Naya, Y. Ichikawa, T. Seki, N.
- Journal Title
  
  Cancer Medicine
  
  Volume: 7(5) Pages: 1988-2002
- DOI
  10.1002/cam4.1455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
[Journal Article] Downregulation of matrix metalloproteinase 14 by the antitumor miRNA, miR-150-5p, inhibits the aggressiveness of lung squamous cell carcinoma cells2018
- Author(s)
  Suetsugu Takayuki、Koshizuka Keiichi、Seki Naohiko、Mizuno Keiko、Okato Atsushi、Arai Takayuki、Misono Shunsuke、Uchida Akifumi、Kumamoto Tomohiro、Inoue Hiromasa
- Journal Title
  
  International Journal of Oncology
  
  Volume: 52 Pages: 913-924
- DOI
  10.3892/ijo.2017.4232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09338
[Journal Article] Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma2018
- Author(s)
  Koshizuka, K., T. Hanazawa, N. Kikkawa, K. Katada, A. Okato, T. Arai, T. Idichi, Y. Osako, Y. Okamoto and N. Seki
- Journal Title
  
  Auris Nasus Larynx.
  
  Volume: - Pages: 854-865
- DOI
  10.1016/j.anl.2017.11.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-17K16778
[Journal Article] Regulation of HMGB3 by antitumor miR-205-5p inhibits cancer cell aggressiveness and is involved in prostate cancer pathogenesis.2018
- Author(s)
  Yamada Yasutaka、Nishikawa Rika、Kato Mayuko、Okato Atsushi、Arai Takayuki、Kojima Satoko、Yamazaki Kazuto、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Pages: 195-205
- DOI
  10.1038/s10038-017-0371-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-16K20125, KAKENHI-PROJECT-17K11160
[Journal Article] Regulation of antitumor miR-144-5p targets oncogenes: Direct regulation of syndecan-3 and its clinical significance.2018
- Author(s)
  Yamada, Y. Arai, T. Kojima, S. Sugawara, S. Kato, M. Okato, A. Yamazaki, K. Naya, Y. Ichikawa, T. Seki, N.
- Journal Title
  
  Cancer Science
  
  Volume: 109 (9) Pages: 2919-2936
- DOI
  10.1111/cas.13722
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-18K16723, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
[Journal Article] Molecular pathogenesis of renal cell carcinoma: Impact of the anti-tumor miR-29 family on gene regulation2018
- Author(s)
  Yamada, Y. Sugawara, S. Arai, T. Kojima, S. Kato, M. Okato, A. Yamazaki, K. Naya, Y. Ichikawa, T. Seki, N.
- Journal Title
  
  International Journal of Urology
  
  Volume: 25(11) Pages: 953-965
- DOI
  10.1111/iju.13783
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-18K16685, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
[Journal Article] Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs2017
- Author(s)
  Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Okamoto Y, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中 Pages: 30288-30304
- DOI
  10.18632/oncotarget.16327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
[Journal Article] Dual Strands of Pre-miR-149 Inhibit Cancer Cell Migration and Invasion through Targeting FOXM1 in Renal Cell Carcinoma2017
- Author(s)
  Okato Atsushi、Arai Takayuki、Yamada Yasutaka、Sugawara Sho、Koshizuka Keiichi、Fujimura Lisa、Kurozumi Akira、Kato Mayuko、Kojima Satoko、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Pages: 1969-1969
- DOI
  10.3390/ijms18091969
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-17K16778, KAKENHI-PROJECT-16H05462
[Journal Article] Involvement of aberrantly expressed microRNAs in the pathogenesis of head and neck squamous cell carcinoma2017
- Author(s)
  Koshizuka Keiichi、Hanazawa Toyoyuki、Arai Takayuki、Okato Atsushi、Kikkawa Naoko、Seki Naohiko
- Journal Title
  
  Cancer metastasis reviews
  
  Volume: 36 Pages: 525-545
- DOI
  10.1007/s10555-017-9692-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893
[Journal Article] Regulation of metastasis-promoting LOXL2 gene expression by antitumor microRNAs in prostate cancer.2017
- Author(s)
  Kato M, Kurozumi A, Goto Y, Matsushita R, Okato A, Nishikawa R, Fukumoto I, Koshizuka K, Ichikawa T, Seki N.
- Journal Title
  
  Journal of Human genetics
  
  Volume: 62 Pages: 123-132
- NAID
  40021036352
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K20125
[Journal Article] Dual strands of pre-miR-150 (miR-150-5p and miR-150-3p) act as antitumor miRNAs targeting SPOCK1 in naive and castration-resistant prostate cancer.2017
- Author(s)
  Okato Atsushi、Arai Takayuki、Kojima Satoko、Koshizuka Keiichi、Osako Yusaku、Idichi Tetsuya、Kurozumi Akira、Goto Yusuke、Kato Mayuko、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  International journal of oncology
  
  Volume: 51 Pages: 245-256
- DOI
  10.3892/ijo.2017.4008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-16K20125
[Journal Article] Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma2017
- Author(s)
  Arai Takayuki、Okato Atsushi、Kojima Satoko、Idichi Tetsuya、Koshizuka Keiichi、Kurozumi Akira、Kato Mayuko、Yamazaki Kazuto、Ishida Yasuo、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Pages: 2088-2101
- DOI
  10.1111/cas.13331
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-17K16778, KAKENHI-PROJECT-16H05462
[Journal Article] Regulation of metastasis-promoting LOXL2 gene expression by antitumor microRNAs in prostate cancer.2017
- Author(s)
  Kurozumi A, Kato M, Goto Y, Matsushita R, Nishikawa R, Okato A, Fukumoto I, Ichikawa T, Seki N.
- Journal Title
  
  J Hum Genet.
  
  Volume: in press Pages: 123-132
- DOI
  10.3892/ijo.2016.3440
- NAID
  40021036352
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-15K20070, KAKENHI-PROJECT-15K20071
[Journal Article] Regulation of metastasis-promoting LOXL2 gene expression by antitumor microRNAs in prostate cancer.2017
- Author(s)
  Kato M, Kurozumi A, Goto Y, Matsushita R, Okato A, Nishikawa R, Fukumoto I, Koshizuka K, Ichikawa T, Seki N.
- Journal Title
  
  J Hum Genet.
  
  Volume: 62 Pages: 123-132
- DOI
  10.1038/jhg.2016.68
- NAID
  40021036352
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-15K20070
[Journal Article] Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer.2017
- Author(s)
  Goto Yusuke、Kurozumi Akira、Arai Takayuki、Nohata Nijiro、Kojima Satoko、Okato Atsushi、Kato Mayuko、Yamazaki Kazuto、Ishida Yasuo、Naya Yukio、Ichikawa Tomohiko、Seki Naohiko
- Journal Title
  
  British journal of cancer
  
  Volume: 117 Pages: 409-420
- DOI
  10.1038/bjc.2017.191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11160, KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-16K20125
[Journal Article] Dual-receptor (EGFR and c-MET) inhibition by tumor-suppressive miR-1 and miR-206 in head and neck squamous cell carcinoma2017
- Author(s)
  Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Matsushita R, Mataki H, Mizuno K, Okamoto Y, Seki N.
- Journal Title
  
  J Hum Genet.
  
  Volume: 62 Pages: 113-121
- DOI
  10.1038/jhg.2016.47
- NAID
  40021036343
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
[Journal Article] The microRNA signatures: aberrantly expressed microRNAs in head and neck squamous cell carcinoma.2017
- Author(s)
  Keiichi Koshizuka, Toyoyuki Hanazawa, Ichiro Fukumoto, Naoko Kikkawa, Yoshitaka Okamoto, Naohiko Seki.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 62 Pages: 3-13
- DOI
  10.1038/jhg.2016.105
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-15K10800
[Journal Article] Regulation of ITGA3 by the anti-tumor miR-199 family inhibits cancer cell migration and invasion in head and neck cancer2017
- Author(s)
  Koshizuka Keiichi、Hanazawa Toyoyuki、Kikkawa Naoko、Arai Takayuki、Okato Atsushi、Kurozumi Akira、Kato Mayuko、Katada Koji、Okamoto Yoshitaka、Seki Naohiko
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Pages: 1681-1692
- DOI
  10.1111/cas.13298
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
[Journal Article] The microRNA expression signature of small cell lung cancer: tumor suppressors of miR-27a-5p and miR-34b-3p and their targeted oncogenes2017
- Author(s)
  Mizuno Keiko、Mataki Hiroko、Arai Takayuki、Okato Atsushi、Kamikawaji Kazuto、Kumamoto Tomohiro、Hiraki Tsubasa、Hatanaka Kazuhito、Inoue Hiromasa、Seki Naohiko
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 62 Pages: 671-678
- DOI
  10.1038/jhg.2017.27
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19458
[Journal Article] Aberrantly expressed microRNAs in bladder cancer and renal cell carcinoma.2017
- Author(s)
  Kurozumi A, Goto Y, Okato A, Ichikawa T, Seki N.
- Journal Title
  
  J Hum Genet.
  
  Volume: 62 Pages: 49-56
- DOI
  10.1038/jhg.2016.84
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-15K20071
[Journal Article] Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer2016
- Author(s)
  Goto Y, Kojima S, Kurozumi A, Kato M, Okato A, Matsushita R, Ichikawa T, Seki N.
- Journal Title
  
  Br J Cancer.
  
  Volume: 114 Pages: 1135-1144
- DOI
  10.1038/bjc.2016.95
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20071
[Journal Article] Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): Inhibition of bladder cancer cell aggressiveness.2016
- Author(s)
  Matsushita R, Yoshino H, Enokida H, Goto Y, Miyamoto K, Yonemori M, Inoguchi S, Nakagawa M, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Pages: 28460-28487
- DOI
  10.18632/oncotarget.8668
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-26462416, KAKENHI-PROJECT-15K20071, KAKENHI-PROJECT-16K20145
[Journal Article] Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma.2016
- Author(s)
  Ichiro Fukumoto, Naoko Kikkawa, Ryosuke Matsushita, Mayuko Kato, Akira Kurozumi, Rika Nishikawa, Yusuke Goto, Keiichi Koshizuka, Toyoyuki Hanazawa, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Journal Title
  
  J Hum Genet.
  
  Volume: 61(2) Pages: 109-118
- DOI
  10.1038/jhg.2015.120
- NAID
  40020742209
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596
[Journal Article] Regulation of LOXL2 and SERPINH1 by antitumor microRNA-29a in lung cancer with idiopathic pulmonary fibrosis.2016
- Author(s)
  Kamikawaji K, Seki N, Watanabe M, Mataki H, Kumamoto T, Takagi K, Mizuno K, Inoue H.
- Journal Title
  
  J Hum GenetJ Hum Genet.
  
  Volume: 12 Pages: 985-993
- NAID
  40021022822
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19458
[Journal Article] Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer.2016
- Author(s)
  Goto Y, Kojima S, Kurozumi A, Kato M, Okato A, Matsushita R, Ichikawa T, Seki N.
- Journal Title
  
  British journal of cancer
  
  Volume: 114 Pages: 1135-44
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K20125
[Journal Article] Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer.2016
- Author(s)
  Kurozumi A, Goto Y, Matsushita R, Fukumoto I, Kato M, Nishikawa R, Sakamoto S, Enokida H, Nakagawa M, Ichikawa T, Seki N.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Pages: 84-94
- DOI
  10.1111/cas.12842
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20071, KAKENHI-PROJECT-25462469, KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-15K20070
[Journal Article] The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma2016
- Author(s)
  Goto Y, Kurozumi A, Nohata N, Kojima S, Matsushita R, Yoshino H, Yamazaki K, Ishida Y, Ichikawa T, Naya Y, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Pages: 59070-59086
- DOI
  10.18632/oncotarget.10887
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20071
[Journal Article] 新前立腺癌学　－最新の基礎研究と診断・治療－　VI. 臨床応用を目指した基礎研究：バイオマーカーの開発：microRNA,2016
- Author(s)
  26.小島聡子、関直彦
- Journal Title
  
  医学書院
  
  Volume: 74（３） Pages: 201-204
- Data Source
  KAKENHI-PROJECT-26462430
[Journal Article] Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer2016
- Author(s)
  Okato A, Goto Y, Kurozumi A, Kato M, Kojima S, Matsushita R, Yonemori M, Miyamoto K, Ichikawa T, Seki N.
- Journal Title
  
  International journal of oncology
  
  Volume: 49 Pages: 111-22
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K20125
[Journal Article] Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer.2016
- Author(s)
  Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Nakagawa M, Enokida H.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 115 Pages: 354-363
- DOI
  10.1038/bjc.2016.179
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-26462416, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K20145
[Journal Article] Dual tumor-suppressors miR-139-5p and miR-139-3p targeting matrix metalloprotease 11 in bladder cancer.2016
- Author(s)
  Yonemori M, Seki N, Yoshino H, Matsushita R, Miyamoto K, Nakagawa M, Enokida H.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Pages: 1233-1242
- DOI
  10.1111/cas.13002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K20145
[Journal Article] The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma2016
- Author(s)
  Fukumoto I, Koshizuka K, Hanazawa T, Kikkawa N, Matsushita R, Kurozumi A, Kato M, Okato A, Okamoto Y, Seki N.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 49（3） Pages: 1119-1129
- DOI
  10.3892/ijo.2016.3602
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
[Journal Article] Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer2016
- Author(s)
  Okato A, Goto Y, Kurozumi A, Kato M, Kojima S, Matsushita R, Yonemori M, Miyamoto K, Ichikawa T, Seki N.
- Journal Title
  
  Int J Oncol.
  
  Volume: 49 Pages: 111-122
- DOI
  10.3892/ijo.2016.3522
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20071
[Journal Article] MicroRNA-205 inhibits cancer cell migration and invasion via modulation of centromere protein F regulating pathways in prostate cancer.2015
- Author(s)
  Nishikawa R, Goto Y, Kurozumi A, Matsushita R, Enokida H, Kojima S, Naya Y, Nakagawa M, Ichikawa T, Seki N
- Journal Title
  
  International Journal of Urology
  
  Volume: 22 Pages: 867-877
- DOI
  10.1111/iju.12829
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20070, KAKENHI-PROJECT-25293333
[Journal Article] MicroRNA expression signature of oral squamous cell carcinoma; functional role of microRNA-26a/b in the modulation of novel cancer pathways2015
- Author(s)
  Fukumoto I, Hanazawa T, Kinoshita T, Kikkawa N, Koshizuka K, Goto Y, Nishikawa R, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 112 Pages: 891-900
- DOI
  10.1038/bjc.2015.19
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-25861528, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-26462596
[Journal Article] MicroRNA-26a/b directly regulate La-related protein 1 and inhibit cancer cell invasion in prostate cancer.2015
- Author(s)
  Kato M, Goto Y, Matsushita R, Kurozumi A, Fukumoto I, Nishikawa R, Sakamoto S, Enokida H, Nakagawa M, Ichikawa T, Seki N.
- Journal Title
  
  Int J Oncol
  
  Volume: 47 Pages: 710-718
- DOI
  10.3892/ijo.2015.3043
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20070, KAKENHI-PROJECT-15K20071, KAKENHI-PROJECT-25462469, KAKENHI-PROJECT-25293333
[Journal Article] Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C.2015
- Author(s)
  Mataki H, Enokida H, Chiyomaru T, Mizuno K, Matsushita R, Goto Y, Nishikawa R, Higashimoto I, Samukawa T, Nakagawa M, Inoue H, Seki N.
- Journal Title
  
  J Hum Genet
  
  Volume: 60 Pages: 53-61
- DOI
  10.1038/jhg.2014.111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-24659407, KAKENHI-PROJECT-25293192
[Journal Article] Functional significance of aberrantly expressed microRNAs in prostate cancer.2015
- Author(s)
  Goto Y, Kurozumi A, Enokida H, Ichikawa T, Seki N.
- Journal Title
  
  Int J Urol
  
  Volume: 22 Pages: 242-252
- DOI
  10.1111/iju.12700
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293333
[Journal Article] Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma.2015
- Author(s)
  Mataki H, Seki N, Chiyomaru T, Enokida H, Goto Y, Kumamoto T, Machida K, Mizuno K, Nakagawa M, Inoue H.
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Pages: 1039-1050
- DOI
  10.3892/ijo.2014.2802
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-24659407, KAKENHI-PROJECT-25293192
[Journal Article] Dual regulation of receptor tyrosine kinase genes EGFR and c-Met by the tumor-suppressive microRNA-23b/27b cluster in bladder cancer.2015
- Author(s)
  Chiyomaru T, Seki N, Inoguchi S, Ishihara T, Mataki H, Matsushita R, Goto Y, Nishikawa R, Tatarano S, Itesako T, Nakagawa M, Enokida H.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 46 Pages: 487-496
- DOI
  10.3892/ijo.2014.2752
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-26462416
[Journal Article] MicroRNA expression signature of castration-resistant prostate cancer: the microRNA-221/222 cluster functions as a tumour suppressor and disease progression marker.2015
- Author(s)
  Goto Y, Kojima S, Nishikawa R, Kurozumi A, Kato M, Enokida H, Matsushita R, Yamazaki K, Ishida Y, Nakagawa M, Naya Y, Ichikawa T, Seki N
- Journal Title
  
  Br J Cancer.
  
  Volume: 113 Pages: 1055-1065
- DOI
  10.1038/bjc.2015.300
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462430, KAKENHI-PROJECT-15K20071, KAKENHI-PROJECT-25293333
[Journal Article] Expression of the tumor suppressive miRNA-23b/27b cluster is a good prognostic marker in clear cell renal cell carcinoma.2014
- Author(s)
  Ishihara T, Seki N, Inoguchi S, Yoshino H, Tatarano S, Yamada Y, Itesako T, Goto Y, Nishikawa R, Nakagawa M, Enokida H.
- Journal Title
  
  The Journal of Urology
  
  Volume: 192 Pages: 1822-1830
- DOI
  10.1016/j.juro.2014.07.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430137, KAKENHI-PROJECT-26861276
[Journal Article] Tumor-suppressive microRNA-218 inhibits cancer cell migration and invasion via targeting of LASP1 in prostate cancer.2014
- Author(s)
  Nishikawa R, Goto Y, Sakamoto S, Chiyomaru T, Enokida H, Kojima S, Kinoshita T, Yamamoto N, Nakagawa M, Naya Y, Ichikawa T, Seki N.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Pages: 802-811
- DOI
  10.1111/cas.12441
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-26462430
[Journal Article] The microRNA expression signature of bladder cancer by deep sequencing: the functional significance of the miR-195/497 cluster.2014
- Author(s)
  Itesako T, Seki N, Yoshino H, Chiyomaru T, Yamasaki T, Hidaka H, Yonezawa T, Nohata N, Kinoshita T, Nakagawa M, Enokida H.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462490
[Journal Article] The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer.2014
- Author(s)
  Goto Y, Kojima S, Nishikawa R, Enokida H, Chiyomaru T, Kinoshita T, Nakagawa M, Naya Y, Ichikawa T, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 7748-7759
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293333
[Journal Article] microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma.2014
- Author(s)
  Kikkawa N, Kinoshita T, Nohata N, Hanazawa T, Yamamoto N, Fukumoto I, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol
  
  Volume: 44 Pages: 2085-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462676
[Journal Article] The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer2014
- Author(s)
  Kojima S, Enokida H, Yoshino H, Itesako T, Chiyomaru T, Kinoshita T, Fuse M, Nishikawa R, Goto Y, Naya Y, Nakagawa M, Seki N.
- Journal Title
  
  J Hum Genet
  
  Volume: 59(2) Pages: 1973-1982
- DOI
  10.1038/jhg.2013.121
- NAID
  40019987497
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791636, KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-26462430
[Journal Article] The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer2014
- Author(s)
  Satoko Kojima, Hideki Enokida, Hirofumi Yoshino, Toshihiko Itesako, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Rika Nishikawa, Yusuke Goto, Yukio Naya, Masayuki Nakagawa and Naohiko Seki
- Journal Title
  
  J Hum Genet
  
  Volume: 59(2) Pages: 78-87
- NAID
  40019987497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592351
[Journal Article] Tumour-suppressive microRNA-224 inhibits cancer cell migration and invasion via targeting oncogenic TPD52 in prostate cancer2014
- Author(s)
  Goto Y, Nishikawa R, Kojima S, Chiyomaru T, Enokida H, Inoguchi S, Kinoshita T, Fuse M, Sakamoto S, Nakagawa M, Naya Y, Ichikawa T, Seki N.
- Journal Title
  
  FEBS Lett
  
  Volume: 588(10) Pages: 1973-1982
- DOI
  10.1016/j.febslet.2014.04.020
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791636, KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-26462430
[Journal Article] microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma2014
- Author(s)
  Kikkawa N, Kinoshita T, Nohata N, Hanazawa T, Yamamoto N, Fukumoto I, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 44(6) Pages: 2085-2092
- DOI
  10.3892/ijo.2014.2349
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25861528
[Journal Article] Tumor-suppressive microRNA-29s inhibit cancer cell migration and invasion via targeting LAMC1 in prostate cancer.2014
- Author(s)
  Nishikawa R, Goto Y, Kojima S, Enokida H, Chiyomaru T, Kinoshita T, Sakamoto S, Fuse M, Nakagawa M, Naya Y, Ichikawa T, Seki N
- Journal Title
  
  Int J Oncol
  
  Volume: 45(1) Pages: 401-10
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  10.3892/ijo.2014.2437
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791636, KAKENHI-PROJECT-25293333, KAKENHI-PROJECT-26462430
[Journal Article] The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer.2014
- Author(s)
  Goto Y, Kojima S, Nishikawa R, Enokida H, Chiyomaru T, Kinoshita T, Nakagawa M, Naya Y, Ichikawa T, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 5（1７） Pages: 7748-7759
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462430
[Journal Article] Identification of tumour suppressive microRNA-451a in hypopharyngeal squamous cell carcinoma based on microRNA expression signature2014
- Author(s)
  Fukumoto I, Kinoshita T, Hanazawa T, Kikkawa N, Chiyomaru T, Enokida H, Yamamoto N, Goto Y, Nishikawa R, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Br J Cancer
  
  Volume: 111 Pages: 386-394
- DOI
  10.1038/bjc.2014.293
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-25861528
[Journal Article] The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer.2014
- Author(s)
  Satoko Kojima, Hideki Enokida, Hirofumi Yoshino, Toshihiko Itesako, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Rika Nishikawa, Yusuke Goto, Yukio Naya, Masayuki Nakagawa and Naohiko Seki.
- Journal Title
  
  J Hum Genet.
  
  Volume: 59(2) Pages: 78-87
- NAID
  40019987497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592351
[Journal Article] Tumour-suppressive microRNA-24-1 inhibits cancer cell proliferation through targeting FOXM1 in bladder cancer.2014
- Author(s)
  Inoguchi S, Seki N, Chiyomaru T, Ishihara T, Matsushita R, Mataki H, Itesako T, Tatarano S, Yoshino H, Goto Y, Nishikawa R, Nakagawa M, Enokida H.
- Journal Title
  
  FEBS letter
  
  Volume: 588 Pages: 3170-3179
- DOI
  10.1016/j.febslet.2014.06.058
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-26462416
[Journal Article] Epithelial–mesenchymal transition-related microRNA-200s regulate molecular targets and pathways in renal cell carcinoma2013
- Author(s)
  Hirofumi Yoshino, Hideki Enokida, Toshihiko Itesako, Shuichi Tatarano, Takashi Kinoshita, Miki Fuse, Satoko Kojima, Masayuki Nakagawa and Naohiko Seki.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 58(8) Pages: 508-16
- DOI
  10.1038/jhg.2013.31
- NAID
  10031195279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592351, KAKENHI-PROJECT-24791636
[Journal Article] Tumor-suppressive microRNA-1291 directly regulates glucose transporter 1 in renal cell carcinoma.2013
- Author(s)
  Yamasaki T, Seki N, Yoshino H, Itesako T, Yamada Y, Tatarano S, Hidaka H, Yonezawa T, Nakagawa M, Enokida H.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Pages: 1411-1419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430137
[Journal Article] MicroRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway.2013
- Author(s)
  Yamasaki T, Seki N, Yoshino H, Itesako T, Hidaka H, Yamada Y, Tatarano S, Yonezawa T, Kinoshita T, Nakagawa M, Enokida H.
- Journal Title
  
  Journal of Urology
  
  Volume: 190 Pages: 1059-2068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430137
[Journal Article] The polycomb protein Ezh2 regulates differentiation and plasticity of CD4+ T helper type 1 and type 2 cells.2013
- Author(s)
  Tumes, D. J., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., Motohashi, S., and Nakayama, T.
- Journal Title
  
  Immunity
  
  Volume: 39 Pages: 819-32
- DOI
  10.1016/j.immuni.2013.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592083, KAKENHI-PROJECT-24790460, KAKENHI-PROJECT-24790461, KAKENHI-PROJECT-25860351, KAKENHI-PROJECT-25860352
[Journal Article] Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma2013
- Author(s)
  Hirofumi Yoshino, Hideki Enokida, Toshihiko Itesako, Satoko Kojima, Takashi Kinoshita, Shuichi Tatarano, Takeshi Chiyomaru, Masayuki Nakagawa and Naohiko Seki.
- Journal Title
  
  Cancer Sci
  
  Volume: 104(12) Pages: 1567-1574
- DOI
  10.1111/cas.12280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592351
[Journal Article] Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma.2013
- Author(s)
  Yoshino H, Enokida H, Itesako T, Kojima S, Kinoshita T, Tatarano S, Chiyomaru T, Nakagawa M, Seki N.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Pages: 1567-1574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430137
[Journal Article] Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma.2013
- Author(s)
  Yamada Y, Hidaka H, Seki N, Yoshino H, Yamasaki T, Itesako T, Nakagawa M, Enokida H.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Pages: 304-312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430137
[Journal Article] Tumour suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma.2013
- Author(s)
  Kinoshita T, Nohata N, Hanazawa T, Kikkawa N, Yamamoto N, Yoshino H, Itesako T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 109 Pages: 2636-2645
- DOI
  10.1038/bjc.2013.607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25670694, KAKENHI-PROJECT-25861528
[Journal Article] Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma2013
- Author(s)
  Nohata N, Hanazawa T, Kinoshita T, Inamine A, Kikkawa N, Itesako T, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Br J Cancer.
  
  Volume: 108 Pages: 1648-1658
- DOI
  10.1038/bjc.2013.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592575, KAKENHI-PROJECT-25861528
[Journal Article] Epithelial-mesenchymal transition-related microRNA-200s regulate molecular targets and pathways in renal cell carcinoma.2013
- Author(s)
  Yoshino H, Enokida H, Itesako T, Tatarano S, Kinoshita T, Fuse M, Kojima S, Nakagawa M, Seki N.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 58 Pages: 1059-1068
- NAID
  10031195279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430137
[Journal Article] Tumor suppressive microRNA-133a regulates novel targets: Moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma.2012
- Author(s)
  Kinoshita T, Nohata N, Fuse M, Hanazawa T, Kikkawa N, Fujimura L, Takano H, Yamada Y, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418 Pages: 1821-1830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249081
[Journal Article] Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma2012
- Author(s)
  Moriya Y, Yoshino I, Seki N et al.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 57 Pages: 38-45
- NAID
  10030662337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591559
[Journal Article] microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers.2012
- Author(s)
  Nohata N, Hanazawa T, Enokida H, Seki N
- Journal Title
  
  Oncotarget
  
  Volume: 3 Pages: 9-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505
[Journal Article] Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma2012
- Author(s)
  Kinoshita T, Nohata N, Yoshino H, Hanazawa T, Kikkawa N, Fujimura L, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 185-93
- DOI
  10.3892/ijo.2011.1196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
[Journal Article] Actin-related protein 2/3 complex subunit5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma2012
- Author(s)
  Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, Hanazawa T, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol
  
  Volume: (印刷中) Pages: 1770-1778
- DOI
  10.3892/ijo.2012.1390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790688, KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
[Journal Article] Tumor suppressive microRNA-133a regulates novel targets: moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma2012
- Author(s)
  Takashi Kinoshita
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418 Pages: 378-83
- DOI
  10.1016/j.bbrc.2012.01.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
[Journal Article] Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.2012
- Author(s)
  Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, Hanazawa T, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol.
  
  Volume: 40 Pages: 1770-1778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249081
[Journal Article] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma.2012
- Author(s)
  Kinoshita T, Hanazawa T, Nohata N, Kikkawa N, Enokida H, Yoshino H, Yamasaki T, Hidaka H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 3 Pages: 1386-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505
[Journal Article] Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer2012
- Author(s)
  1) Miki Fuse, Satoko Kojima,Enokida H, Chiyomaru T, Yoshino H, Niziro Nohata, Takashi Kinoshita, Shinich Sakamoto, Yukio Naya, Masayuki Nakagawa, Tomohiko Ichikawa, Naohiko Seki.
- Journal Title
  
  J Hum Genet
  
  Volume: 57(11) Pages: 691-699
- DOI
  10.1038/jhg.2012.95
- NAID
  10031126990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592351, KAKENHI-PROJECT-24791636
[Journal Article] The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways2012
- Author(s)
  Kinoshita T, Hanazawa T, Nohata N, Okamoto Y, Seki N
- Journal Title
  
  J Hum Genet
  
  Volume: 57 Pages: 556-563
- DOI
  10.1038/jhg.2012.75
- NAID
  10031056783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24592590
[Journal Article] Tumor suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer2012
- Author(s)
  Kojima S, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nohata N, Fuse M, Ichikawa T, Naya Y, Nakagawa M, Seki N.
- Journal Title
  
  Brit. J. Can
  
  Volume: 106(2) Pages: 405-413
- DOI
  10.1038/bjc.2011.462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390420, KAKENHI-PROJECT-23592351, KAKENHI-PROJECT-24592590
[Journal Article] Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma.2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Fujimura L, Yoshino H, Kawakami K, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  Int J Oncol. 38(1)
  
  Pages: 209-217
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] Mir-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma : correlation with stage and grade, and comparison with urinary cytology.2011
- Author(s)
  Yasutoshi Yamada, Hideki Enokida, Satoko Kojima, Kazumori Kawakami, Takeshi Chiyomaru, Shuichi Tatarano, Hirofumi Yoshino, Kazuya Kawahara, Kenryu Nishiyama, Naohiko Seki, Masayuki Nakagawa.
- Journal Title
  
  Cancer Sci 102(3)
  
  Pages: 522-529
- NAID
  10029290902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791530
[Journal Article] LY6K is a novel molecular target in bladder cancer on basis of integrate genome-wide profiling.2011
- Author(s)
  Matsuda R, Enokida H, Chiyomaru T, Kikkawa N, Sugimoto T, Kawakami K, Tatarano S, Yoshino H, Toki K, Uchida Y, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
- Journal Title
  
  Br J Cancer. 104
  
  Pages: 376-386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines.2011
- Author(s)
  Yoshitomi T, Kawakami K, Enokida H, Chiyomaru T, Kagara I, Tatarano S, Yoshino H, Arimura H, Nishiyama K, Seki N, Nakagawa M.
- Journal Title
  
  Oncol Rep. 25
  
  Pages: 1661-1668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer.2011
- Author(s)
  Tatarano S, Chiyomaru T, Kawakami K, Enokida H, Yoshino H, Hidaka H, Yamasaki T, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
- Journal Title
  
  Int J Oncol. 39
  
  Pages: 13-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Sakurai D, Sasaki K, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 1099-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] Mir-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology.2011
- Author(s)
  Yamada Y et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 522-529
- DOI
  10.1111/j.1349-7006.2010.01816.x
- NAID
  10029290902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501298, KAKENHI-PROJECT-23592351
[Journal Article] Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata
- Journal Title
  
  Br J Cancer
  
  Volume: 105 Pages: 833-41
- DOI
  10.1038/bjc.2011.311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505
[Journal Article] Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC)2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Sakurai D, Fujimura L, Kawakami K, Chiyomaru T, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  J Hum Genet
  
  Volume: 56 Pages: 595-601
- NAID
  40018947302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1.2011
- Author(s)
  Fuse M, Nohata N, Kojima S, Sakamoto S, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, Naya Y, Ichikawa T, Seki N.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 38(4) Pages: 1093-1101
- DOI
  10.3892/ijo.2011.919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390420, KAKENHI-PROJECT-21592032, KAKENHI-PROJECT-23592351
[Journal Article] Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Fujimura L, Yoshino H, Kawakami K, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  Int J Oncol
  
  Volume: 38 Pages: 209-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma : correlation with stage and grade, and comparison with urinary cytology.2011
- Author(s)
  Yamada Y, Enokida H, Kojima S, Kawakami K, Chiyomaru T, Tatarano S, Yoshino H, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
- Journal Title
  
  Cancer Sci. 102
  
  Pages: 522-529
- NAID
  10029290902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] MiR-133a induces apoptosis through direct regulation of GSTP1 in bladder cancer cell lines.2011
- Author(s)
  Uchida Y, Chiyomaru T, Enokida H, Kawakami K, Tatarano S, Kawahara K, Nishiyama K, Seki N, Nakagawa M.
- Journal Title
  
  Urol Oncol. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Sakurai D, Fujimura L, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nakagawa M, Katayama A, Harabuchi Y, Okamoto Y, Seki N
- Journal Title
  
  Br J Cancer
  
  Volume: 105 Pages: 833-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1.2011
- Author(s)
  Miki Fuse, Nijiro Nohata, Satoko Kojima, Shinichi Sakamoto, Takeshi Chiyomaru, Kazumori Kawakami, Hideki Enokida, Masayuki Nakagawa, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
- Journal Title
  
  Int.J.Oncol. 38
  
  Pages: 1093-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791530
[Journal Article] The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer.2011
- Author(s)
  Yoshino H, Chiyomaru T, Enokida H, Kawakami K, Tatarano S, Nishiyama K, Nohata N, Seki N, Nakagawa M.
- Journal Title
  
  Br J Cancer. 104
  
  Pages: 808-818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma2011
- Author(s)
  Nohata N, Sone Y, Hanazawa T, Fuse M, Kikkawa N, Yoshino H, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, Shozu M, Okamoto Y, Seki N
- Journal Title
  
  Oncotarget
  
  Volume: 2 Pages: 29-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] 前立腺がんにおけるマイクロＲＮＡ発現プロファイル2011
- Author(s)
  小島聡子、納谷幸男、市川智彦、関直彦
- Journal Title
  
  日本臨床　増刊号　前立腺癌（第2版）
  
  Volume: 24(8) Pages: 92-95
- Data Source
  KAKENHI-PROJECT-23592351
[Journal Article] Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 1099-107
- DOI
  10.3892/ijo.2011.1096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505
[Journal Article] miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer.2010
- Author(s)
  Chiyomaru T, Enokida H, Tatarano S, Kawahara K, Uchida Y, Nishiyama K, Fujimura L, Kikkawa N, Seki N, Nakagawa M.
- Journal Title
  
  Br J Cancer. 102
  
  Pages: 883-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC)2010
- Author(s)
  Kikkawa N, Hanazawa T, Fujimura L, Nohata N, Suzuki H, Chazono H, Sakurai D, Horiguchi S, Okamoto Y, Seki N
- Journal Title
  
  Br J Cancer
  
  Volume: 103 Pages: 877-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] マイクロRNA(miR-145、miR-133a・b)の頭頸部扁平上皮癌における増殖・浸潤抑制機能と標的遺伝子の同定2010
- Author(s)
  花澤豊行, 吉川直子, 野畑二次郎, 堅田浩司, ムラディル・ムラリフ, 鈴木誉, 佐々木慶太, 茶薗英明, 堀口茂俊, 岡本美孝, 関直彦
- Journal Title
  
  頭頸部癌 36(1)
  
  Pages: 1-8
- NAID
  10029079202
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC).2010
- Author(s)
  Kikkawa N, Hanazawa T, Fujimura L, Nohata N, Suzuki H, Chazono H, Sakurai D, Horiguchi S, Okamoto Y, Seki N.
- Journal Title
  
  Br J Cancer. 7;103(6)
  
  Pages: 877-884
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] Identification of novel microRNA targets based on microRNA signatures in bladder cancer.2009
- Author(s)
  Ichimi T, Enokida H, Okuno Y, Kunimoto R, Chiyomaru T, Kawamoto K, Kawahara K, Toki K, Kawakami K, Nishiyama K, Tsujimoto G, Nakagawa M, Seki N.
- Journal Title
  
  Int J Cancer. 125
  
  Pages: 345-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390427
[Journal Article] Prediction of lymph node metastasis by gene expression profiling in patients with primary resected lung cancer2009
- Author(s)
  Moriya Y, Iyoda A, Kasai Y, Sugimoto T, Hashida J, Nimura Y, Kato M, Takiguchi M, Fujisawa T, Seki N, Yoshino I
- Journal Title
  
  Lung Cancer 64
  
  Pages: 86-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591610
[Journal Article] The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.2009
- Author(s)
  Sugimoto T, Seki N, Shimizu S, Kikkawa N, Tsukada J, Shimada H, Sasaki K, Hanazawa T, Okamoto Y, Hata A
- Journal Title
  
  Genes Chromosomes Cancer. 48(2)
  
  Pages: 132-142
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] Identification of a novel therapeutic target for head and neck squamous cell carcinomas : A role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway.2008
- Author(s)
  Shimizu S, Tsukada J, Sugimoto T, Kikkawa N, Sasaki K, Chazono H, Hanazawa T, Okamoto Y, Seki N
- Journal Title
  
  Int J Cancer. 15;123(8)
  
  Pages: 1816-1823
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] Identification of differentially expressed genes in human bladder cancer through genome-wide gene expression profiling2006
- Author(s)
  Kawakami K, Enokida H, Tachiwada T, Gotanda T, Tsuneyoshi K, Kubo H, Nishiyama K, Takiguchi M, Nakagawa, M, Seki N.
- Journal Title
  
  Oncology Reports (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591603
[Journal Article] WISP-2 expression in human salivary gland tumors2006
- Author(s)
  Kouzu Y, Uzawa K, Kato M, Higo M, Nimura Y, Harada K, Numata T, Seki N, Sato M, Tanzawa H
- Journal Title
  
  Int J Mol Med 17
  
  Pages: 567-573
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209059
[Journal Article] Identification of candidate radioresistant genes in human squamous cell carcinoma cells through gene expression analysis using DNA microarrays.2005
- Author(s)
  Higo M, Uzawa K, Kouzu Y, Bukawa H, Nimura Y, Seki N, Tanzawa H.
- Journal Title
  
  Oncol Rep. 14
  
  Pages: 1293-1298
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591189
[Journal Article] In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines.2003
- Author(s)
  Moriya T, Seki N, Shimada K, Kato M, Yakushiji T, Nimura Y, Uzawa K, Takiguchi M
- Journal Title
  
  Int J Mol Med. 12
  
  Pages: 429-435
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390608
[Journal Article] In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines.2003
- Author(s)
  Moriya T, Seki N, Shimada K, Kato M, Yakushiji T, Nimura Y, Uzawa K, Takiguchi M, Tanzawa H.
- Journal Title
  
  Int J Mol Med 12
  
  Pages: 429-435
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390608
[Patent] microRNA発現プロファイリングに基づく尿路上皮癌の検出方法2010
- Inventor(s)
  関直彦、榎田英樹、中川昌之
- Industrial Property Rights Holder
  国立大学法人千葉大学、国立大学法人鹿児島大学
- Industrial Property Number
  2010-159384
- Filing Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-20390427
[Patent] microRNA発現プロファイリングに基づく膀胱癌の検出方法2009
- Inventor(s)
  関直彦, 中川昌之
- Industrial Property Rights Holder
  千葉大学、鹿児島大学
- Patent Publication Number
  2009-100687
- Filing Date
  2009-05-14
- Data Source
  KAKENHI-PROJECT-20390427
[Patent] microRNA発現プロファイリングに基づく尿路上皮癌の検出方法2007
- Inventor(s)
  関直彦、榎田英樹、中川昌之
- Industrial Property Rights Holder
  国立大学法人千葉大学、国立大学法人鹿児島大学
- Industrial Property Number
  2007-276191
- Filing Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] 癌抑制型microRNA-144 の制御する腎癌分子ネットワークの探索2019
- Author(s)
  山田康隆、菅原翔、新井隆之、岡東篤、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 転移性前立腺癌における遠隔リンパ節の予後因子としての重要性2019
- Author(s)
  小島聡子、加藤智規、増田広、荒木千裕、巣山貴仁、芳生旭辰、大塚耕太郎、三神功亮、関根啓太、納谷幸男
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 癌抑制型マイクロRNA-99a-3p を起点とした去勢抵抗性前立腺癌・治療標的分子の探索2019
- Author(s)
  新井隆之、小島聡子、山田康隆、菅原翔、岡東篤、納谷幸男、市川智彦、関直彦
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 癌抑制型 microRNA-451a の制御する腎癌分子ネットワークの探索2018
- Author(s)
  山田康隆、菅原翔、新井隆之、岡東篤、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第 106 回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] Antitumor miR-451a regulatory network is associated with poor prognosis of renal cell carcinoma2018
- Author(s)
  Y. Yamada, S. Sugawara, T. Arai, A. Okato, S. Kojima, Y. Naya, T. Ichikawa, N. Seki.
- Organizer
  AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 癌抑制型マイクロ RNA(miR-10a-5p) が制御する治療抵抗性腎癌・新規分子ネットワークの探索2018
- Author(s)
  新井隆之、岡東篤、小島聡子、黒住顕、加藤繭子、納谷幸男、市川智彦、関直彦
- Organizer
  第 106 回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 癌抑制型マイクロＲＮＡにより制御される細胞周期関連遺伝子NCAPGは、去勢知恵構成前立腺癌の治療法的分子である2018
- Author(s)
  新井隆之、岡東篤、山田康隆、菅原翔、黒住顕、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第27回　泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] Regulation of NCAPG by miR-99a-3p (passenger strand) inhibits cancer cell aggressiveness and is involved in CRPC2018
- Author(s)
  T. Arai, A. Okato, Y. Yamada, S. Sugawara, A. Kurozumi, S. Kojima, Y. Naya, T. Ichikawa, N. Seki.
- Organizer
  AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 腎細胞癌・マイクロ RNA 発現プロファイルに基づく、機能性 RNA ネットワークの探索2018
- Author(s)
  岡東篤、新井隆之、山田康隆、菅原翔、黒住顕、加藤繭子、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第 106 回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 癌抑制型microRNA-451の制御する腎癌分子ネットワークの探索2018
- Author(s)
  山田康隆、菅原翔、新井隆之、岡東篤、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第27回　泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 治療抵抗性腎癌細胞で発現低下を認めるmiR-10aの機能解析と新規機能性RNA分子ネットワークの探索2017
- Author(s)
  新井隆之、五島悠介、岡東篤、黒住顕、加藤繭子、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 癌抑制型microRNA-320aが制御する前立腺癌分子ネットワークの探索2017
- Author(s)
  岡東篤、五島悠介、黒住顕、加藤繭子、新井隆之、小島聡子、市川智彦、関直彦
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 新規癌抑制型マイクロRNA(miR-145-3p)を基点とした去勢抵抗性前立腺癌・治療標的分子の探索2017
- Author(s)
  黒住顕、五島悠介、野畑二次郎、小島聡子、新井隆之、岡東篤、加藤繭子、納谷幸男、市川智彦、関直彦
- Organizer
  第26回泌尿器科分子・細胞研究会
- Place of Presentation
  全労済ソレイユ (大分)
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly regulate metastasis-promoting LOXL2 in prostate cancer2017
- Author(s)
  Mayuko Kato, Akira Kurozumi, Yusuke Goto, Ryosuke Matsushita, Ichiro Fukumoto, Atsushi Okato, Rika Nishikawa, Shinichi Sakamoto, Tomohiko Ichikawa, Naohiko Seki
- Organizer
  American Association for Cancer Research Annual meeting 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana, USA
- Year and Date
  2017-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20125
[Presentation] Impact of antitumore microRNA-145-3p regulated RNA networks in castration-resistant prostate cancer.2017
- Author(s)
  Akira Kurozumi, Yusuke Goto, Nijiro Nohata, Satoko Kojima, Takayuki Arai, Atsushi Okato, Mayuko Kato, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  American Urology Association 2017 in Boston
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] MicroRNA expression signature of patients with tyrosine kinase inhibitors failure: miR-10a-5p inhibits cancer cell aggressiveness in renal cell carcinoma.2017
- Author(s)
  Takayuki Arai, Atsushi Okato, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Keiichi Koshizuka, Satoko Kojima, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] miR-150前駆体から派生する2種類のマイクロRNA（miR-150-5p, miR-150-3p）は前立腺癌において癌抑制機能を有する2017
- Author(s)
  岡東篤、新井隆之、黒住顕、加藤繭子、五島悠介、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第26回泌尿器科分子・細胞研究会
- Place of Presentation
  全労済ソレイユ (大分)
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) are involved in castration-resistant prostate cancer pathogenesis.2017
- Author(s)
  Mayuko Kato, Akira Kurozumi, Yusuke Goto, Nijiro Nohata, Takayuki Arai, Atsushi Okato, Keiichi Koshizuka, Satoko Kojima, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 前立腺癌ゲノムシークエンスにより明らかとなった新規癌抑制型マイクロRNA (miR-150-5p/miR-150-3p)の機能解析2017
- Author(s)
  岡東篤、五島悠介、黒住顕、加藤繭子、新井隆之、小島聡子、市川智彦、関直彦
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] TKI治療抵抗性腎細胞癌・マイクロRNA発現プロファイル：microRNA-10a-5pの機能解析と標的分子の探索2017
- Author(s)
  新井隆之、岡東篤、黒住顕、加藤繭子、五島悠介、小島聡子、納谷幸男、市川智彦、関直彦
- Organizer
  第26回泌尿器科分子・細胞研究会
- Place of Presentation
  全労済ソレイユ (大分)
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] 前立腺疾患機能性RNA解析に基づく前立腺癌特異的分子ネットワークの探索2017
- Author(s)
  岡東篤、小島聡子、市川智彦、関直彦
- Organizer
  第33回前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] 次世代シークエンサーを用いた頭頸部扁平上皮癌・マイクロＲＮＡ発現プロファイルに基づく新規癌抑制型マイクロＲＮＡの探索2017
- Author(s)
  吉川直子　越塚慶一　花澤豊行　福本一郎　岡本美孝　関直彦
- Organizer
  第41回頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-16K11224
[Presentation] Impact of microRNA expression signature of patients with TKI failure:regulation of miR-10a-5p pathways in renal cell carcinoma．2017
- Author(s)
  Takayuki Arai, Atsushi Okato, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Satoko Kojima, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  American Urology Association 2017 in Boston
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] Dual-strands pre-microRNA-150 (miR-150-5p and miR-150-3p) acts as tumor suppressor in prostate cancer.2017
- Author(s)
  Atsushi Okato, Takayuki Arai, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Keiichi Koshizuka, Satoko Kojima, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] miR-452 inhibits migration and invasion of prostate cancer cells by targeting E3 ubiquitin ligase-1 (WWP1).2017
- Author(s)
  Satoko Kojima, Yusuke Goto, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Takayuki Arai, Tomohiko Ichikawa, Yukio Naya, Naohiko Seki.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] Tumor-suppressive microRNA-26a-5p/-26b-5p inhibit cancer cell migration and invasion through targeting PLOD2 that is a potential prognostic maker in bladder cancer.2017
- Author(s)
  Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Sakaguchi T, Sugita S, Enokida H, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  Boston (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293354
[Presentation] The microRNA expression signature of patients with renal cell carcinoma: Tumor suppressive miR-149-5p targeting FOXM1.2017
- Author(s)
  Atsushi Okato, Takayuki Arai, Akira Kurozumi, Mayuko Kato, Yusuke Goto, Satoko Kojima, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  American Urology Association 2017 in Boston
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11160
[Presentation] Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) are involved in castration-resistant prostate cancer pathogenesis2017
- Author(s)
  Mayuko Kato, Akira Kurozumi, Yusuke Goto, Nijiro Nohata, Takayuki Arai, Atsushi Okato, Keiichi Koshizuka, Satoko Kojima, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20125
[Presentation] 機能性RNAネットワークの解析に基づく去勢抵抗性前立腺癌治療標的分子の同定2016
- Author(s)
  黒住顕、五島悠介、小島聡子、市川智彦、関直彦
- Organizer
  第32回前立腺シンポジウム
- Place of Presentation
  東京コンファレンスセンター (品川)
- Year and Date
  2016-12-10
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] 頭頸部扁平上皮癌において癌抑制型miR-1/206はEGFRとc-METを制御する．2016
- Author(s)
  11.越塚慶一, 花澤豊行, 福本一郎, 吉川直子, 松下良介, 俣木浩子, 水野圭子, 岡本美孝, 関直彦．
- Organizer
  第75回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26462596
[Presentation] Dual-strands of microRNA-139 (miR-139-5p and miR-139-3p) targeting matrix metalloprotease 11 (MMP11) in bladder cancer2016
- Author(s)
  Yonemori M, Seki N, Yoshino H, Matsushita R, Miyamoto K, Nakagawa M, Enokida H.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] Identification of dual tumorsuppressors (miR-225p/miR-223p) based on microRNA expression signature by deep sequencing of CRPC.2016
- Author(s)
  Yusuke Goto, Satoko Kojima, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Yukio Naya, Hideki Enokida, Ryosuke Matsushita, Masayuki Nakagawa, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  American Urology Association
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Dual tumor-suppressors (miR-145-5p/miR-145-3p) inducing cancer cell apoptosis via direct targeting UHRF1 in bladder cancer2016
- Author(s)
  Matsushita R, Seki N, Yoshino H, Miyamoto K, Yonemori M, Kurozumi A, Goto Y, Enokida H, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  San Diego (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293354
[Presentation] 全ゲノムCRPC機能性RNA発現解析に基づくCRPC活性化分子経路の探索2016
- Author(s)
  五島悠介、小島聡子、松下良介、黒住顕、加藤繭子、西川里佳、坂本信一、榎田英樹、中川昌之、納谷幸男、市川智彦、関直彦
- Organizer
  第104回日本泌尿器科学会総会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Tumor suppressive miRNA-26a/b inhibit cell migration and invasion through targeting a prognostic marker, Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) in bladder cancer.2016
- Author(s)
  Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Nakagawa M, Enokida H.
- Organizer
  第68回西日本泌尿器科学会
- Place of Presentation
  海峡メッセ下関（山口県下関市）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] Regulation of UHRF1mediated pathways by tumorsuppressive microRNA101 in molecular targeted therapy resistant renal cell carcinoma.2016
- Author(s)
  Yusuke Goto, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Satoko Kojima, Ryosuke Matsushita, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  American Urology Association
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-05-06
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Dual tumor-suppressors miR-139-5p/-3p derived from pre-miR-139 via targeting matrix metalloprotease 11 (MMP11) in bladder cancer2016
- Author(s)
  Yonemori M, Seki N, Matsushita R, Miyamoto K, Yoshino H, Goto Y, Kato M, Kurozumi A, Nakagawa M, Enokida H
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  San Diego (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293354
[Presentation] microRNA-320aはLAMP1の発現を抑制して前立腺癌細胞の遊走・浸潤を制御する2016
- Author(s)
  岡東篤、五島悠介、黒住顕、加藤繭子、小島聡子、坂本信一、松下良介、榎田英樹、中川昌之、市川智彦、関直彦
- Organizer
  第25回泌尿器科分子・細胞研究会
- Place of Presentation
  ハイアットリージェンシー大阪（大阪府大阪市）
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] 全ゲノムシークエンス解析によって明らかとなった去勢抵抗性前立腺癌・癌抑制型マイクロRNAクラスター（miR-221/222）の機能解析2016
- Author(s)
  五島悠介、黒住顕、小島聡子、加藤繭子、岡等篤、坂本信一、松下良介、榎田英樹、中川昌之、市川智彦、関直彦
- Organizer
  第25回泌尿器科分子・細胞研究会
- Place of Presentation
  ハイアットリージェンシー大阪（大阪府大阪市）
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Identification of dual tumor-suppressors (miR-222-5p/miR-222-3p) based on microRNA expression signature by deep sequencing of CRPC.2016
- Author(s)
  Goto Y, Kojima S, Kurozumi A, Kato M, Okato A, Sakamoto S, Naya Y, Enokida H, Matsushita R, Nakagawa M, Ichikawa T, Seki N.
- Organizer
  AUA annual meeting 2016
- Place of Presentation
  San Diego Convention Center, San Diego, 米国　カリフォルニア州
- Year and Date
  2016-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05462
[Presentation] Dual tumor-suppressors (miR-145-5p/miR-145-3p) inducing cancer cell apoptosis via direct targeting UHRF1 in bladder cancer2016
- Author(s)
  Matsushita R, Seki N, Yoshino H, Miyamoto K, Yonemori M, Kurozumi A, Goto Y, Enokida H, and Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  San Diego（USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462416
[Presentation] Targeting multiple functions of E3 ubiquitin ligase-1 (WWP1) signaling by miR-452 inhibits cancer cell migration and invasion in prostate cancer.2015
- Author(s)
  Goto Y, Kurozumi A, Nishikawa R, Kato M, Sakamoto S, Kojima S, Naya Y Enokida H, Nakagawa M, Ichikawa T, Seki N.
- Organizer
  AUA annual meeting 2015
- Place of Presentation
  New Orleans Morial Convention Center, New Orleans, 米国　ルイジアナ州
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293333
[Presentation] GOLM1は複数の癌抑制型microRNAによって制御される前立腺癌の新規癌遺伝子である2015
- Author(s)
  五島悠介、小島聡子、黒住顕、西川里佳、加藤繭子、千代丸剛、榎田英樹、中川昌之、納谷幸男、市川智彦、関直彦
- Organizer
  第103回日本泌尿器科学会総会
- Place of Presentation
  ホテル日航金沢（石川県、金沢市）
- Year and Date
  2015-04-18
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] 去勢抵抗性前立腺癌マイクロＲＮＡ発現プロファイルに基づく新規分子ネットワークの解析.2015
- Author(s)
  小島聡子、五島悠介、西川里佳、黒住顕、千代丸剛、榎田英樹、中川昌之、市川智彦、山崎一人、石田康生、関直彦、納谷幸男
- Organizer
  第103回日本泌尿器科学会総会
- Place of Presentation
  ホテル日航金沢（石川県、金沢市）
- Year and Date
  2015-04-18
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] CRPC臨床検体を用いた機能性RNA発見解析に基づくCRPC治療標的活性化経路の探索2015
- Author(s)
  五島悠介、小島聡子、市川智彦、関直彦
- Organizer
  第31回前立腺シンポジウム
- Place of Presentation
  東京コンファレンスセンター・品川（東京都、港区）
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] 去勢抵抗性前立腺癌マイクロRNA発現プロファイルに基づいた癌抑制型miR-22/222クラスターの機能解析2015
- Author(s)
  五島悠介、小島聡子、西川里佳、松下良介、福本一郎、坂本信一、榎田英樹、中川昌之、納谷幸男、市川智彦、関直彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Targeting multiple functions of E3 ubiquitin ligase-1 (WWP1) signaling by miR-452 inhibits cancer cell migration and invasion in prostate cancer.2015
- Author(s)
  Yusuke Goto, Akira Kurozumi, Rika Nishikawa, Mayuko Kato, Shinichi Sakamoto, Satoko Kojima, Yukio Naya, Hideki Enokida, Masayuki Nakagawa, Tomohiko Ichikawa, Naohiko Seki.
- Organizer
  AUA 2015 （米国泌尿器科学会）
- Place of Presentation
  ニューオーリンズ（アメリカ合衆国）
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Tumor suppressive microRNA-218 inhibites cancer cell migration and invasion via targeting LASP1 in prostate cancer2014
- Author(s)
  Nishikawa R, Goto Y, Kinoshita T, Sakamoto S, Chiyomaru T, Enokida H, Kojima S, Nakagawa M, Naya Y, Ichikawa T, Seki N.
- Organizer
  AACR 2014 annual meeting
- Place of Presentation
  San Diego Convention Center (San Diego, USA)
- Data Source
  KAKENHI-PROJECT-25293333
[Presentation] 癌抑制型microRNAによって制御されるGOLM1は前立腺癌の新規癌遺伝子である2014
- Author(s)
  西川里佳、五島悠介、坂本信一、千代丸　剛、榎田英樹、小島聡子、中川昌之、納谷幸男、市川智彦、関　直彦
- Organizer
  第23回泌尿器科分子・細胞研究会
- Place of Presentation
  山形テルサ（山形県山形市）
- Data Source
  KAKENHI-PROJECT-25293333
[Presentation] 複数の癌抑制型microRNAによって制御されるGOLM1は前立腺癌の新規癌遺伝子である2014
- Author(s)
  五島悠介、西川里佳、坂本信一、千代丸　剛、榎田英樹、小島聡子、中川昌之、納谷幸男、市川智彦、関　直彦
- Organizer
  第23回泌尿器科分子・細胞研究会
- Place of Presentation
  山形テルサ（山形県山形市）
- Data Source
  KAKENHI-PROJECT-25293333
[Presentation] 下咽頭癌においてｍｉＲ－５０４はＣＤＫ６の制御を介して細胞増殖を抑制する2014
- Author(s)
  吉川直子　花澤豊行　木下崇　福本一郎　岡本美孝　関直彦
- Organizer
  第38回　日本頭頸部癌学会
- Place of Presentation
  東京ファッションタウンビル（東京都江東区）
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-25462676
[Presentation] 癌抑制型microRNAが制御する前立腺癌転移機構の解明2013
- Author(s)
  五島悠介、西川里佳、坂本信一、小島聡子、市川智彦、関　直彦
- Organizer
  第29回前立腺シンポジウム
- Place of Presentation
  東京コンファレンスセンター品川（東京都港区）
- Data Source
  KAKENHI-PROJECT-25293333
[Presentation] Expression signature of tumor-suppressive miRNA and control of cancer associated molecular pathways in prostate cancer.2013
- Author(s)
  5) Satoko Kojima, Hideki Enokida, Hirohumi Yoshino, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Yukio Naya, Masayuki Nakagawa, Naohiko Seki
- Organizer
  第104回AUA Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] Expression signature of tumor-suppressive miRNA and control of cancer associated molecular pathways in prostate cancer2013
- Author(s)
  Satoko Kojima, Hideki Enokida, Hirohumi Yoshino, Takeshi Chiyomaru, Takashi Kinoshita, Miki Fuse, Yukio Naya, Masayuki Nakagawa, Naohiko Seki
- Organizer
  第104回AUA Annual Meeting 2013
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma2013
- Author(s)
  Takashi Kinoshita, Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Noriko Yamamoto, Hideki Enokida, Hirofumi Yoshino, Takeshi Yamasaki, Hideo Hidaka, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR Annual 104th Meeting
- Place of Presentation
  Washington, DC, USA)
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] Identification of pureine nucleoside phosphorylase (PNP) as a novel target of tumor suppressors miR-1 and MiR-133a in prostate cancer2012
- Author(s)
  Satoko Kojima, Takeshi Chiyomaru, Hirofumi Yoshino, Hideki Enokida, Nijiro Nohata, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
- Organizer
  第103回AUA annual meeting
- Place of Presentation
  Atlanta, GA USA(Abstract No 487)
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] Tumor suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer2012
- Author(s)
  Satoko Kojima, Takeshi Chiyomaru, Hideki Enokida, Kazumori Kawakami, Hirofumi Yoshino, Nijiro Nohata, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
- Organizer
  27^<th> EAU
- Place of Presentation
  Paris(abstract No 842)
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] microRNA-874 as a tumor suppressor in maxillary sinus squamous cell carcinoma based on microRNA expression signature2012
- Author(s)
  Toyoyuki Hanazawa, Nijiro Nohata, Takashi Kinoshita,Naoko Kikkawa,Miki Fuse, Takeshi Chiyomaru, Hirofumi Yoshinoi, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 103rd Annual Meeting
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] 前立腺癌におけるmicro-RNA発現プロファイルと遺伝子制御の探索2012
- Author(s)
  小島聡子、布施美樹、千代丸剛、野畑二次郎、木下崇、吉野裕史、榎田英樹、中川昌之、市川智彦、納谷幸男、関直彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] 癌抑制型microRNA-874が制御する頭頸部扁平上皮癌の新規分子ネットワークの解明2012
- Author(s)
  花澤豊行、野畑二次郎、木下崇、吉川直子、堅田浩司、茶薗英明、岡本美孝、関直彦
- Organizer
  第36回日本頭頸部癌学会学術講演会
- Place of Presentation
  島根県民会館島根
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] MicroRNAs detection in urine as diagnostic markers and predictors of recurrence of non-muscle invasive bladder cancer.2012
- Author(s)
  Hideki Enokida, Yasutoshi Yamada, Hirofumi Yoshino, Shuichi Tatarana, Hideo Hidaka, Takeshi Yamasaki, Takeshi Chiyomaru, Satoko Kojima, Naohiko Seki, Masayuki Nakagawa.
- Organizer
  第103回　米国泌尿器科学会AUA annual meeting
- Place of Presentation
  アトランタ
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] Tumor suppressive microRNA-1 and microRNA-133a cluster regulating molecular targets in head and neck squamous cell carcinoma2012
- Author(s)
  Nijiro Nohata, Toyoyuki Hanazawa, Takashi Kinoshita, Naoko Kikkawa, Daiju Sakurai, Miki Fuse, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  8th International Conference on Head and Neck Cancer
- Place of Presentation
  Toronto, ON, Canada
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] Tumor suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer2012
- Author(s)
  Satoko Kojima, Takeshi Chiyomaru, Hideki Enokida, Kazumori Kawakami, Hirofumi Yoshino,Nijiro Nohata3, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
- Organizer
  27ｔｈ　Ａｎｎｕａｌ　ＥＡＵ　ｃｏｎｇｒｅｓｓ
- Place of Presentation
  Paris France
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] Identification of pureine nucleoside phosphorylase (PNP) as a novel target of tumor suppressors miR-1 and MiR-133a in prostate cancer.2012
- Author(s)
  Satoko Kojima, Takeshi Chiyomaru, Hirofumi Yoshino, Hideki Enokida, Nijiro Nohata, Miki Fuse, Tomohiko Ichikawa, Yukio Naya, Masayuki Nakagawa, and Naohiko Seki
- Organizer
  第103回　米国泌尿器科学会AUA annual meeting
- Place of Presentation
  アトランタ
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] 癌抑制型microRNA-874が制御する頭頸部扁平上皮癌の新規分子ネットワークの解明2012
- Author(s)
  花澤豊行、野畑二次郎、木下崇、吉川直子、堅田浩司、茶薗英明、岡本美孝、関直彦
- Organizer
  第36回日本頭頸部癌学会
- Place of Presentation
  島根県民会館（島根）
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] Tumor suppressive microRNA-1/-133a regulates multiple oncogenes in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata, Toyoyuki Hanazawa, Takashi Kinoshita, Naoko Kikkawa, Muradil Mutallip, Takeshi Chiyomaru, Kazumori Kawakami, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Rhodes Island, Greece
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] The tumor suppressive miRNA cluster of miR-1 and miR-133a targets oncogenic TAGLN2 gene in bladder cancer.2011
- Author(s)
  Yoshino H, Enokida H, Seki N, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  Washington DC
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] 前立腺癌におけるmiR-1およびmiR-133aの機能解析と標的遺伝子PNPの同定2011
- Author(s)
  小島聡子、千代丸剛、川上一盛、榎田英樹、野畑二次郎、布施美樹、吉野裕史、稲原昌彦、中川昌之、納谷幸男、関直彦
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  京都(P-2101)
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] Functional role of LASP1 in bladder cancer cell viability and its regulation by microRNAs.2011
- Author(s)
  Chiyomaru T, Enokida H, Seki N, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  Washington DC
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] Identification of tumor suppressive micro RNAs in maxillary sinus squamous cell carcinoma based on micro RNA expression signature2011
- Author(s)
  Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Akihiro Katayama, Yasuaki Harabuchi, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] miR-218 on the genomic loss region of chromosome 4P15.31 functions as a tumor suppressor in bladder cancer.2011
- Author(s)
  Tatarano S, Enokida H, Seki N, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  Washington DC
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] miR-133a as a tumor suppressive microRNA targeting multiple oncogenes in head neck squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Miki Fuse, Takeshi Chiyomaru, Kazumori Kawakami, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] Tumor suppressive microRNA-375 targeting multiple oncogenes in maxillary sinus squamous cell carcinoma (MSSCC)2011
- Author(s)
  Takashi Kinoshita, Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Mutallip Muradil, Hirofumi Yoshino, Kazumori Kawakami, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場名古屋
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] Identification of tumor suppressive microRNAs in maxillary sinus squamous cell carcinoma based on microRNA expression signature2011
- Author(s)
  Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Akihiro Katayama, Yasuaki Harabuchi, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] 前立腺癌におけるmiR-1およびmiR-133aの機能解析と標的遺伝子PNPの同定2011
- Author(s)
  小島聡子、千代丸剛、川上一盛、榎田英樹、野畑二次郎、布施美樹、吉野裕史、稲原昌彦、中川昌之、納谷幸男、関直彦
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23592351
[Presentation] MicroRNAs (miR-96 and miR-183) detection serves as urine markers in patients with urothelial carcinoma.2011
- Author(s)
  Enokida H, Seki N, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  Washington DC
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines.2011
- Author(s)
  Yoshitomi T, Enokida H, Seki N, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  Washington DC
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] 前立腺癌におけるmiR-200 familyおよびmiR-205の機能解析2010
- Author(s)
  小島聡子、榎田英樹、千代丸剛、中川昌之、稲原昌彦、納谷幸男、関直彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21791530
[Presentation] 進行前立腺癌におけるmicroRNAのプロファイル解析2010
- Author(s)
  小島聡子、榎田英樹、千代丸剛、稲原昌彦、中川昌之、納谷幸男、関直彦
- Organizer
  第19回泌尿器分子・細胞研究会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-21791530
[Presentation] MiR-133a functions as a tumor suppressor and directly regulates GSTP1 expression in bladder cancer.2010
- Author(s)
  Uchida Y, Enokida H, Seki N, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting.
- Place of Presentation
  San Francisco
- Year and Date
  2010-05-31
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] miR-145 and miR-133a function as tumor suppressors and directly regulate FSCN1 expression in bladder cancer.2010
- Author(s)
  Chiyomaru T, Enokida H, Seki N, Nakagawa M.
- Organizer
  European Association of Urology (EAU) annual meeting
- Place of Presentation
  Barcelona
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation]2009
- Author(s)
  Satoko Kojima, Ryoko Watanabe, Jun Tsukada, Yuzo Furuya, Naohiko Seki.
- Organizer
  The 100^<th> AUA annual meeting MiR-15a functions as a tumor suppressor for prostate cancer by targeting multiple oncogenes.
- Place of Presentation
  Chicago, Illinois, USA.
- Data Source
  KAKENHI-PROJECT-21791530
[Presentation] MiR-15a functions as a tumor suppressor for prostate cancer by targeting multiple oncogenes.2009
- Author(s)
  Satoko Kojima, Ryoko Watanabe, Jun Tsukada, Yuzo Furuya, Naohiko Seki
- Organizer
  EUA The 24^<th> annual congress of European association of urology, 17-21 march 2009 Stockholm, Sweden Abstract 777.
- Place of Presentation
  Stockholm, Sweden.
- Data Source
  KAKENHI-PROJECT-21791530
[Presentation] 進行前立腺癌におけるmicroRNAの発現解析2009
- Author(s)
  小島聡子、有馬雅史、榎田英樹、千代丸剛、中川昌之、稲原昌彦、関直彦
- Organizer
  第68回日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21791530
[Presentation] Identification of differentially expressed mature microRNAs in bladder cancer.2008
- Author(s)
  Enokida H, Seki N, Nakagawa M.
- Organizer
  23rd Annual European Association of Urology Congress(EAU)
- Place of Presentation
  Milan
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-20390427
[Presentation] The functional significance and its regulated molecular targets of microRNA-23b/27b/24-1 cluster in prostate cancer.
- Author(s)
  Goto Y, Nishikawa R, Kojima S, Sakamoto S, Kawamura K, Imamoto T, Chiyomaru T, Enokida H, Kinoshita T, Naya Y, Nakagawa M, Ichikawa T, Seki N.
- Organizer
  American Urological Association annual meeting 2014
- Place of Presentation
  米国フロリダ州オーランド市　Orange County Convention Center
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25293333
[Presentation] マイクロRNA-143/145クラスターは前立腺癌において、GOLM1を標的とし、癌抑制遺伝子として機能する
- Author(s)
  小島聡子、榎田英樹、吉野裕史、井出迫俊彦、千代丸剛、木下崇、五島悠介、布施美紀、西川里佳、納谷幸男、中川昌之、関直彦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  （パシフィコ横浜）横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Tumour suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOKM1 in prostate cancer
- Author(s)
  S.Kojima, H.Enomoto, H.Yoshino, T.Itesako, T.Chiyomaru, T.Kinoshita, M.Fuse, Y.Goto, R.Nishikawa, Y.Naya, M.Nakagawa, N Seki
- Organizer
  29th Annual EAU Congress
- Place of Presentation
  Stockholm(ｽｳｪｰﾃﾞﾝ）
- Year and Date
  2014-04-11 – 2014-04-15
- Data Source
  KAKENHI-PROJECT-26462430
[Presentation] Tumor suppressive microRNA-224 inhibits cancer cell migration and invasion via targeting TPD52 in prostate cancer.
- Author(s)
  Goto Y, Nishikawa R, Kojima S, Sakamoto S, Kawamura K, Imamoto T, Chiyomaru T, Enokida H, Kinoshita T, Naya Y, Nakagawa M, Ichikawa T, Seki N.
- Organizer
  American Urological Association annual meeting 2014
- Place of Presentation
  米国フロリダ州オーランド市　Orange County Convention Center
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25293333

1. HANAZAWA Toyoyuki (90272327)

# of Collaborated Projects: 9 results

# of Collaborated Products: 46 results
2. ENOKIDA Hideki (80347103)

# of Collaborated Projects: 8 results

# of Collaborated Products: 35 results
3. TANZAWA Hideki (50236775)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
4. UZAWA Katsuhiro (30302558)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
5. NAKAGAWA Masayuki (90164144)

# of Collaborated Projects: 7 results

# of Collaborated Products: 32 results
6. KOJIMA Satoko (10345019)

# of Collaborated Projects: 6 results

# of Collaborated Products: 92 results
7. IYODA Akira (10302548)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
8. SHIBUYA Kiyoshi (20302565)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
9. Mizuno Keiko (50531414)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
10. 夏越祥次 (70237577)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
11. FUJISAWA Takehiko (80110328)

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# of Collaborated Products: 0 results
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# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 4 results

# of Collaborated Products: 45 results
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# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
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# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
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# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
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# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
21. INOGUCHI Satoru

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
22. ISHIHARA Tomoaki

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
23. Matsushita Ryousuke

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
24. Miyamoto Kazutaka

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
25. Yonemori Masaya

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
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# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
27. MOTOHASHI Shinichiro (60345022)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
28. Ichiro Fukumoto (70748764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
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# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
30. KATAOKA Kazunori (00130245)

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31. MIYATA Kanjiro (50436523)

# of Collaborated Projects: 2 results

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32. SHIMADA Hideaki (20292691)

# of Collaborated Projects: 2 results

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# of Collaborated Projects: 2 results

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44. AMANO Hideki (60296481)

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
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# of Collaborated Projects: 1 results

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47. ITESAKO Toshihiko (10642613)

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51. SHIBA Masashi (20301096)

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52. HAYASHI Hedeki (20312960)

# of Collaborated Projects: 1 results

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53. OCHIAI Takenori (80114255)

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54. GUNJI Yoshio (60241957)

# of Collaborated Projects: 1 results

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55. ABIKO Yoshimitsu (70050086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
56. NISHIYAMA Kenryu (80264422)

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58. KIM Sung-gon (70255694)

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59. OHSAWA Aki (50407251)

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# of Collaborated Projects: 1 results

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61. TANAKA Yuriko (40396685)

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62. TAKIGUCHI Yuichi (30272321)

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63. KUROSU Kstsushi (20291106)

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64. SUZUKI Makoto (80312957)

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65. YASUFUKU Kazuhiro (60372356)

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66. NAKAJIMA Takahiro (20400913)

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85. 戸田洋子 (90814301)

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86. 新田吉陽 (20725733)

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89. 和田真澄 (60836112)

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90. KURAHARA Hiroshi

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91. SHINODA Kenta

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# of Collaborated Products: 1 results
92. UCHIKADO Yasuto

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# of Collaborated Products: 1 results
93. ARIGAMI Takaaki

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# of Collaborated Products: 1 results
94. NAYA Yukio

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# of Collaborated Products: 1 results
95. KIJIMA Yuko

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# of Collaborated Products: 1 results
96. INAMINE Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
97. 五島悠介

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# of Collaborated Products: 9 results
98. 木下崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
99. 堅田浩司

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# of Collaborated Products: 4 results
100. 布施美樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
101. 西川里佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
102. 滝口正樹

# of Collaborated Projects: 0 results

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103. 藤村理紗

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
104. 川崎洋太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
105. 前村公成

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
106. 又木雄弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
107. 高野晴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
108. 鈴木茜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
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# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
110. 小野寺淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
111. 佐々木健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
112. 寒川卓哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Seki Naohiko 関 直彦

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SEKI Naohiko 関 直彦

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頭頸部癌・転写調節領域を指標とした薬剤耐性に関与する機能性RNA分子の探索Principal InvestigatorOngoing

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マイクロRNAを起点とした肺扁平上皮癌に関する分子経路と新規治療法の探索研究Ongoing

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小細胞肺癌の機能性RNA統合解析に基づくドラッグ・リポジショニングの考案Ongoing

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機能性RNA統合理解に基づく間質性肺炎合併肺癌の分子経路探索と新規治療法の開発Ongoing

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Elucidation of therapeutic target molecular pathway by understanding tripli negative breast cancer and functional RNA integrationOngoing

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Elucidation of molecular pathogenesis of esophageal squamous cell carcinoma based on comprehensive functional RNA analysisOngoing

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機能性RNAを起点とした治療抵抗性頭頸部扁平上皮癌のドラッグリポジション戦略Ongoing

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消化器癌個別化治療にむけた3D培養と共培養を用いた癌組織不均一性の基礎研究Ongoing

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Project Period (FY)

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機能性RNA解析に基づく頭頚部扁平上皮癌治療抵抗性獲得機序の探索Principal InvestigatorOngoing

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Principal Investigator

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Seki Naohiko 関直彦

関直彦セキナオヒコ

SEKI Naohiko 関直彦