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ASOU Yoshinori  麻生 義則

Researcher Number 50345279
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-1892-1524
Affiliation (Current) 2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help 2025: 東京科学大学, 東京医科歯科大学病院, 非常勤講師
2023: 東京医科歯科大学, 東京医科歯科大学病院, 非常勤講師
2019 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, ジョイントリサーチ講座教授
2015 – 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座准教授
2013 – 2016: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 … More
2014 – 2015: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授
2014: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座准教授
2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄付講座准教授
2012: 東京医科歯科大学, 医歯学総合研究科, 寄付講座教員
2011 – 2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄付講座教員
2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄付講座教員
2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄附講座講師
2010 – 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄附講座教員
2010: 東京医科歯科大学, 医学部附属病院, 助教
2009: Tokyo Medical and Dental University, 医歯学総合研究科, 寄附講座教員
2009: 東京医科歯科大学, 医歯学総合研究科, 寄附講座講師
2008: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師
2007 – 2008: Tokyo Medical and Dental University, Department of Orthopaedic Surgery, Assistant Professor
2007: Tokyo Medical and Dental University, University Hospital Faculty of Medicine, Assistant Professor
2005 – 2007: 東京医科歯科大学, 医学部附属病院, 助手
2004: 国立大学法人東京医科歯科大学, 疾患遺伝子実験センター, 助手
2002 – 2003: 東京医科歯科大学, 疾患遺伝子実験センター, 助手 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Basic Section 56070:Plastic and reconstructive surgery-related / Orthopaedic surgery / 疼痛学
Keywords
Principal Investigator
加齢 / Sirt6 / 老化 / PAI-1 / Runx2 / 骨代謝 / サーチュイン / 山中カクテル / 若返り / 間葉系幹細胞 … More / 腸内細菌叢 / 運動器 / 腸内細菌 / 骨粗鬆症 / サルコペニア / 筋肉 / 骨 / Sirt6 / PAI-1 / 骨細胞 / SOST / FGF23 / ageing / osteoporosis / SIRT6 / キサンチンオキシドリダクターゼ / 膝蓋下脂肪体 / 変形性膝関節症 / 高脂肪食 / 尿酸代謝 / キサンチンオキシダーゼ / 尿酸 / メタボリックシンドローム / 変形性関節症 / animal model / degeneration of intervertebral disc / 間歇的軸圧負荷モデル / Rux2 / 動物モデル / 椎間板変性 / 軟骨代謝 / 軟骨 / Sirt1 … More
Except Principal Investigator
骨代謝 / 変形性関節症 / PAI-1 / 破骨細胞 / 変形性膝関節症 / Runx / 骨芽細胞 / 肉腫 / 骨粗鬆症 / MMP-3 / 椎間板変性 / 軟骨代謝 / 骨細胞 / 老化 / Runx遺伝子 / 脂質代謝 / 形成外科 / 再建 / 遊離皮弁 / ナノバブル水 / ナノバブル水の投与組成の検討 / 実験動物モデルの手技獲得 / RNAseq解析 / 増殖 / p21 / p53 / G2-M arrest / osteosarcoma / U2OS / がん幹細胞 / 加齢 / Sirt4 / サーチュイン / 骨軟骨 / senescence / Sirt6 / 薬理学 / 骨吸収 / 骨形成 / 閉経 / Degeneration of intervertebral disc / TEWAK / TWEAK / laser microdissection / animal model / degeneration of intervertebral disc / 分子生物学 / 網羅的検索 / マイクロダイゼクション / マイクロダイゼクション法 / 動物モデル / transgenic mouse / osteoarthritis / 分子病態 / トランスジェニックマウス / scaffold / mesenchymal stem cell / osteoclast / osteoblast / sheet / Porous body / anterior fusion of spine / Col) composite / type I collagen (HAp / Hydroxyapatite / rhBMP-2 / 人工椎体 / Col複合体 / HAp / 骨髄間葉系細胞 / 骨伝導能 / コラーゲン / 骨代替材料 / 頚椎前方固定システム / Col) / コラーゲン(HAp / 骨形成能 / 骨髄細胞 / コラーゲンナノ複合体 / 水酸アパタイト / 間葉系幹細胞 / シート / 多孔体 / 頚椎前方固定 / PLLAプレート / コラーゲン複合体 / アパタイト / I型コラーゲン / ハイドロキシアパタイト / 成長ホルモン / 臓器連関 / ポリフェノール / 腸内細菌 / 腸内フローラ / アントシアニジン / レニン・アンジオテンシン系 / 臓器間クロストーク / 血圧調節 / 軟骨細胞 / プロレニン受容体 / 血圧調節機構 / シグナル伝達機構 / 活性酸素 / 酸化ストレス / Knee Pain / Lysholm Score / 前十字靭帯再建術(ACL) / Visual Analogue Score (VAS) / 変形性関節症(OA) / Visual Analogue Scale(VAS) / VAS / 関節炎 / オステオポンチン(OPN) / 関節液 / 前十字靭帯損傷 / 膝疼痛 / Osteopontin / TNF / 関節軟骨 / RANKL / RANK / OPG / 軟骨発生 / 軟骨分化 / 軟骨再生 / 遺伝子治療 / 関節病学 / Runx3 / 靭帯骨化症 / 脊椎脊髄病学 / 糖代謝 / 網羅的解析 / 高脂肪食 / obマウス / ob / 脂肪細胞分化 / スクリーニング / 骨芽細胞分化 / 非翻訳RNA / RNA干渉 Less
  • Research Projects

    (28 results)
  • Research Products

    (172 results)
  • Co-Researchers

    (42 People)
  •  線溶系による運動器加齢制御メカニズムの解明Principal Investigator

    • Principal Investigator
      麻生 義則
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Institute of Science Tokyo
  •  酸素ナノバブル水は再建手術の時間を止めるか~耐低酸素能と皮弁阻血時間に着目して~

    • Principal Investigator
      上野 麻由
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Tokyo Medical and Dental University
  •  間葉系幹細胞リプログラミングによるRejuvenationの挑戦Principal Investigator

    • Principal Investigator
      麻生 義則
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of novel sarcoma treatment guidelines targeting the sarcoma microenvironment

    • Principal Investigator
      Katsushi Kikuchi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Nippon Medical School
      Tokyo Medical and Dental University
  •  Molecular mechanisms of locomotor degenerative changes due to crosstalk of aging control factorsPrincipal Investigator

    • Principal Investigator
      ASOU YOSHINORI
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of novel anti-sarcoma drug based on PAI-1 regulation

    • Principal Investigator
      Katsushi Kikuchi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular mechanisms of locomotor degenerative changes due to intestinal agingPrincipal Investigator

    • Principal Investigator
      ASOU YOSHINORI
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Prevention of osteoporosis and osteonecrosis by novel PAI-1 inhibitor

    • Principal Investigator
      Koga Daisuke
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  The role of xanthin oxydase in the etiology of osteoarthritisPrincipal Investigator

    • Principal Investigator
      ASOU Yoshinori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  The rola of Sirt6 in bone and cartilage metabolism

    • Principal Investigator
      OKAWA Atsushi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of novel osteoporosis medication which focusses on the renin angiotensin system in osteocytes

    • Principal Investigator
      Morita Sadao
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  The effect of anthocyanidin on skeletal antiaging

    • Principal Investigator
      Daisuke Koga
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Clarification of the crosstalk between bone and brain.

    • Principal Investigator
      OKAWA Atsushi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of the role of Sirt6 in the chondrocyte metabolismPrincipal Investigator

    • Principal Investigator
      ASOU Yoshinori
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of the role of reactive oxygen species in bone metabolism

    • Principal Investigator
      MORITA Sadao
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Clarification of the crosstalk between bone and blood pressure control.

    • Principal Investigator
      OKAWA Athushi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Osteopontin Level in Synovial Fluid is Associated with the Severity of Joint Pain and Cartilage Degeneration After Anterior Cruciate Ligament Rupture

    • Principal Investigator
      JYU Neishin
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      疼痛学
    • Research Institution
      Tokyo Medical and Dental University
  •  Investigation of the molecular mechanisms through which SIRT1 modulates osteoarthritis progression.Principal Investigator

    • Principal Investigator
      ASO Yoshinori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Investigation of the molecular mechanisms through which osteoclast differentiation regulating factors modulates osteoarthritis progression.

    • Principal Investigator
      KOGA Daisuke
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of the molecular pathogenesis of calcification of the ligament

    • Principal Investigator
      AE Keisuke
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of the regulatory mechanism of early chondrocyte differentiation and application of cartilage repair

    • Principal Investigator
      JINNO Tetsuya
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular analysis of the mechanisms for articular cartilage degeneration induced by metabolic syndrome

    • Principal Investigator
      KOTO Tsuyoshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Identification and characterization of a novel regulatory factor for the determination of osteoblast-adipocyte differentiation using RNA interference

    • Principal Investigator
      ARAI Yoshiyasu
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular analysis for the mechanisms of endoplate sclerosis using laser microdissection technique

    • Principal Investigator
      KOGA Daisuke
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  The mechanism of low back pain and establish for new strategy of treatment

    • Principal Investigator
      HARO Hirotaka
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      University of Yamanashi
  •  Molecular analysis for the mechanisms of intervertebral disc degeneration using experimental animal modelPrincipal Investigator

    • Principal Investigator
      ASOU Yoshinori
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of the molecular pathogenesis of osteoarthritis

    • Principal Investigator
      JINNO Tetsuya
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of the artificial bone using a novel biomaterial HAp/Col composite and PLLA

    • Principal Investigator
      ITOH Soichiro
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Patent

  • [Journal Article] Correction:PAI-1 inhibitor TM5614 leads osteosarcoma cells to G2 arrest2024

    • Author(s)
      Gulinazi Anniwaer Kunikazu Tsuji Shingo Sato Toshio Miyata Atsushi Okawa Yoshinori Asou
    • Journal Title

      Journal of Medical and Dental Sciences

      Volume: 71 Issue: 0 Pages: 1-10

    • DOI

      10.11480/jmds.710001

    • ISSN
      1342-8810, 2185-9132
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09244
  • [Journal Article] PAI‐1 antagonist ameliorates hypophosphatemia in the Hyp vitamin D‐resistant rickets model mouse2023

    • Author(s)
      Qian Cheng、Ito Nobuaki、Tsuji Kunikazu、Sato Shingo、Kikuchi Katsushi、Yoshii Toshitaka、Miyata Toshio、Asou Yoshinori
    • Journal Title

      FEBS Open Bio

      Volume: 14 Issue: 2 Pages: 290-299

    • DOI

      10.1002/2211-5463.13745

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19580, KAKENHI-PROJECT-20KK0205, KAKENHI-PROJECT-22K09302, KAKENHI-PROJECT-21K09293, KAKENHI-PROJECT-21K19556, KAKENHI-PROJECT-23K24455
  • [Journal Article] SIRT6-PAI-1 axis is a promising therapeutic target in aging-related bone metabolic disruption2023

    • Author(s)
      Aobulikasimu Alkebaier、Liu Tao、Piao Jinying、Sato Shingo、Ochi Hiroki、Okawa Atsushi、Tsuji Kunikazu、Asou Yoshinori
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 1-16

    • DOI

      10.1038/s41598-023-33297-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19580, KAKENHI-PROJECT-21K19556, KAKENHI-PROJECT-23K24455, KAKENHI-PROJECT-18H02920
  • [Journal Article] Osteolytic Bone Loss and Skeletal Deformities in a Mouse Model for Early-Onset Paget’s Disease of Bone with PFN1 Mutation Are Treatable by Alendronate2023

    • Author(s)
      Ling Zhu、Aini Hailati、Kajikawa Shuhei、Shirakawa Jumpei、Tsuji Kunikazu、Asou Yoshinori、Koga Hideyuki、Sekiya Ichiro、Nifuji Akira、Noda Masaki、Ezura Yoichi
    • Journal Title

      Pharmaceuticals

      Volume: 16 Issue: 10 Pages: 1395-1395

    • DOI

      10.3390/ph16101395

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19580, KAKENHI-PROJECT-21K09823
  • [Journal Article] PAI-1 inhibitor TM5614 leads osteosarcoma cells to G2 arrest2023

    • Author(s)
      Anniwaer Gilinazi Tsuji Kunikazu Sato Shingo Miyata Toshio Okawa Atsushi Asou Yoshinori
    • Journal Title

      Journal of Medical and Dental Sciences

      Volume: 70 Issue: 0 Pages: 23-32

    • DOI

      10.11480/jmds.700003

    • ISSN
      1342-8810, 2185-9132
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09244
  • [Journal Article] A novel PAI-1 inhibitor prevents ageing-related muscle fiber atrophy.2021

    • Author(s)
      Aihemaiti A, Yamamoto N, Piao J, Oyaizu T, Ochi H, Sato S, Okawa A, Miyata T, Tsuji K, Ezura Y, Asou Y.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 534 Pages: 849-856

    • DOI

      10.1016/j.bbrc.2020.10.089

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09096, KAKENHI-PROJECT-19K22680, KAKENHI-PROJECT-18H02920, KAKENHI-PROJECT-18K19604, KAKENHI-PROJECT-19H03777, KAKENHI-PROJECT-21K19556
  • [Journal Article] Effects of long-term plate fixation with different fixation modes on the radial cortical bone in dogs.2021

    • Author(s)
      Muroi N, Ochi H, Shimada M, Asou Y, Hara Y.
    • Journal Title

      PLoS One.

      Volume: Feb 19;16(2) Issue: 2 Pages: e0247410-e0247410

    • DOI

      10.1371/journal.pone.0247410

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Journal Article] PAI-1活性制御によるサルコペニア予防の可能性2020

    • Author(s)
      麻生 義則・アディハム アハマット
    • Journal Title

      月刊「細胞」

      Volume: 52 Pages: 709-712

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Journal Article] PAI-1活性制御によるサルコペニア予防の可能性2020

    • Author(s)
      麻生 義則, アディハム・アハマット
    • Journal Title

      月刊「細胞」

      Volume: 52 (12) Pages: 709-712

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19604
  • [Journal Article] Proanthocyanidin-rich grape seed extract improves bone loss, bone healing, and implant osseointegration in ovariectomized animals2020

    • Author(s)
      Tenkumo T, Aobulikasimu A, Asou Y, Shirato M, Shishido S, Kanno T, Niwano Y, Sasaki K, Nakamura K.
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 8812-8812

    • DOI

      10.1038/s41598-020-65403-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10180, KAKENHI-PROJECT-18H02920, KAKENHI-PROJECT-18K19604
  • [Journal Article] Expression of type II collagen and aggrecan genes is regulated through distinct epigenetic modifications of their multiple enhancer elements2019

    • Author(s)
      Nham Giang Thi Hien、Zhang Xiang、Asou Yoshinori、Shinomura Tamayuki
    • Journal Title

      Gene

      Volume: 704 Pages: 134-141

    • DOI

      10.1016/j.gene.2019.04.034

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06248, KAKENHI-PROJECT-18H02920, KAKENHI-PROJECT-17K11000
  • [Journal Article] Proanthocyanidin-rich grape seed extract modulates intestinal microbiota in ovariectomized mice2018

    • Author(s)
      Jin G, Asou Y, Ishiyama K, Okawa A, Kanno T, Niwano Y
    • Journal Title

      J Food Sci

      Volume: 印刷中 Issue: 4 Pages: 661-666

    • DOI

      10.1111/1750-3841.14098

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07788, KAKENHI-PROJECT-17K11000, KAKENHI-PROJECT-18H00490
  • [Journal Article] A small molecule PAI-1 inhibitor prevents bone loss by stimulating bone formation in a murine estrogen deficiency-induced osteoporosis model2018

    • Author(s)
      Jin G, Aobulikasimu A, Piao J, Aibibula Z, Koga D, Sato S, Ochi H, Tsuji K, Nakabayashi T, Miyata T, Okawa A, Asou Y.
    • Journal Title

      FEBS Open Bio

      Volume: 8(4) Issue: 4 Pages: 523-532

    • DOI

      10.1002/2211-5463.12390

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10847, KAKENHI-PROJECT-17K11000, KAKENHI-PROJECT-26293332
  • [Journal Article] Intraoperative evaluation of the effects of femoral component offset and head size on joint stability in total hip arthroplasty2017

    • Author(s)
      Jinno Tetsuya、Koga Daisuke、Asou Yoshinori、Morita Sadao、Okawa Atsushi、Muneta Takeshi
    • Journal Title

      Journal of Orthopaedic Surgery

      Volume: 25 Issue: 1

    • DOI

      10.1177/2309499016684298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15541
  • [Journal Article] Limited significance of screening computed tomography after cementless total hip arthroplasty with highly cross-linked polyethylene at 7-10 years of follow-up.2016

    • Author(s)
      Takada R, Jinno T, Koga D, Yamauchi Y, Asou Y, Muneta T, Okawa A.
    • Journal Title

      Mod Rheumatol

      Volume: Feb16 Pages: 1-4

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462361
  • [Journal Article] Xanthine oxidoreductase activation is implicated in the onset of metabolic arthritis.2016

    • Author(s)
      Aibibula Z, Ailixiding M, Iwata M, Piao J, Hara Y, Okawa A, Asou Y.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 472 Issue: 1 Pages: 26-32

    • DOI

      10.1016/j.bbrc.2016.02.039

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15541, KAKENHI-PROJECT-26293332
  • [Journal Article] Pleiotropic Functions of High Fat Diet in the Etiology of Osteoarthritis.2016

    • Author(s)
      Asou Y, Iwata M, Ochi H, Ailixiding M, Aibibula Z, Piao J, Jin G, Hara Y, Okawa A.
    • Journal Title

      PLoS One.

      Volume: 11 Issue: 9 Pages: e0162794-e0162794

    • DOI

      10.1371/journal.pone.0162794

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01633, KAKENHI-PROJECT-26713048, KAKENHI-PROJECT-15K15545, KAKENHI-PROJECT-15K15541, KAKENHI-PROJECT-26293332
  • [Journal Article] Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis.2015

    • Author(s)
      Ailixiding M, Aibibula Z, Iwata M, Piao J, Hara Y, Koga D, Okawa A, Morita S, Asou Y.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 466 Issue: 3 Pages: 319-326

    • DOI

      10.1016/j.bbrc.2015.09.019

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462361, KAKENHI-PROJECT-26293332
  • [Journal Article] Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis.2015

    • Author(s)
      Kobayashi K1, Nojiri H2, Saita Y2, Morikawa D1, Ozawa Y3, Watanabe K3, Koike M1, Asou Y4, Shirasawa T5, Yokote K6, Kaneko K2, Shimizu T3.
    • Journal Title

      Scientific Reports

      Volume: Mar 16;5 Issue: 1 Pages: 9148-9148

    • DOI

      10.1038/srep09148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791568, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-26462319, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
  • [Journal Article] Enhancement of Runx2 expression is potentially linked to β-catenin accumulation in canine intervertebral disc degeneration.2015

    • Author(s)
      Iwata M, Aikawa T, Hakozaki T, Arai K, Ochi H, Haro H, Tagawa M, Asou Y, Hara Y.
    • Journal Title

      J Cell Physiol.

      Volume: Jan;230(1) Issue: 1 Pages: 180-190

    • DOI

      10.1002/jcp.24697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-26293332
  • [Journal Article] 人工股関節全置換術におけるトラネキサム酸静脈内投与の効果と凝固線溶系に与える影響2015

    • Author(s)
      平尾昌之· 神野哲也· 古賀大介· 高田亮平· 瀬川裕子· 星野ちさと· 麻生義則· 森田定雄· 宗田大· 大川淳
    • Journal Title

      Hip Joint

      Volume: 41 Pages: 292-299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462360
  • [Journal Article] MicroRNA-145 regulates osteoblastic differentiation by targeting the transcription factor Cbfb.2015

    • Author(s)
      Fukuda T, Ochi H, Sunamura S, Haiden A, Bando W, Inose H, Okawa A, Asou Y, Takeda S.
    • Journal Title

      FEBS Lett.

      Volume: 589 Issue: 21 Pages: 3302-8

    • DOI

      10.1016/j.febslet.2015.09.024

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15543, KAKENHI-PROJECT-15K15545, KAKENHI-PROJECT-25253090, KAKENHI-PROJECT-25462381, KAKENHI-PROJECT-26293332, KAKENHI-PROJECT-26713048
  • [Journal Article] Tumor necrosis factor-α enhances RANKL expression in gingival epithelial cells via protein kinase A signaling.2014

    • Author(s)
      Fujihara R, Usui M, Yamamoto G, Nishii K, Tsukamoto Y, Okamatsu Y, Sato T, Asou Y, Nakashima K, Yamamoto M.
    • Journal Title

      J Periodontal Res.

      Volume: Aug;49(4) Issue: 4 Pages: 503-507

    • DOI

      10.1111/jre.12131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Journal Article] Massive bone reconstruction with heat-treated bone graft loaded autologous bone marrow-derived strom al cells andβ-tricalcium phosphate composites in canine models2013

    • Author(s)
      Koyanagi H, Ae K, Maehara H, Yuasa M, Masaoka T, Yamada T, Taniyama T, Saito M, Funauchi Y, Yoshii T, Okawa A, Sotome S
    • Journal Title

      J Orthop Res

      Volume: 31(8) Issue: 8 Pages: 1308-16

    • DOI

      10.1002/jor.22368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592179, KAKENHI-PROJECT-25670637
  • [Journal Article] Variations in gene and protein expression in canine chondrodystrophic nucleus pulposus cells following long-term three-dimensional culture.2013

    • Author(s)
      Iwata M, Ochi H, Asou Y, Haro H, Aikawa T, Harada Y, Nezu Y, Yogo T, Tagawa M, Hara Y.
    • Journal Title

      PLoS One

      Volume: May 2;8(5)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Journal Article] Sema3A regulates bone-mass accrual through sensory innervations2013

    • Author(s)
      Fukuda T, Takeda S, Xu R, Ochi H, Sunamura S, Sato T, Shibata S, Yoshida Y, Gu Z, Kimura A, Ma C, Xu C, Bando W, Fujita K, Shinomiya K, Hirai T, Asou Y, Enomoto M, Okano H, Okawa A, Itoh H
    • Journal Title

      Nature.

      Volume: 497 Issue: 7450 Pages: 490-493

    • DOI

      10.1038/nature12115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22600011, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24592188, KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791565, KAKENHI-PROJECT-25670637
  • [Journal Article] Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading.2013

    • Author(s)
      Morikawa D, Nojiri H, Saita Y, Kobayashi K, Watanabe K, Ozawa Y, Koike M, Asou Y, Takaku T, Kaneko K, Shimizu T.
    • Journal Title

      J Bone Miner Res

      Volume: november 28(11) Issue: 11 Pages: 2368-80

    • DOI

      10.1002/jbmr.1981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791568
  • [Journal Article] Initial Responses of Articular Tissues in a Murine High-Fat Diet-Induced Osteoarthritis Model: Pivotal Role of the IPFP as a Cytokine Fountain.2013

    • Author(s)
      Iwata M, Ochi H, Hara Y, Tagawa M, Koga D, Okawa A, Asou Y.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 4 Pages: e60706-e60706

    • DOI

      10.1371/journal.pone.0060706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791565, KAKENHI-PROJECT-25462361, KAKENHI-PROJECT-25670637
  • [Journal Article] After repeated division, bone marrow stromal cells express inhibitory factors with osteogenic capabilities, and EphA5 is a primary candidate2013

    • Author(s)
      Yamada T, Yuasa M, Masaoka T, Taniyama T, Maehara H, Torigoe I, Yoshii T, Shinomiya K, Okawa A, Sotome S
    • Journal Title

      Bone

      Volume: 57(2) Issue: 2 Pages: 343-54

    • DOI

      10.1016/j.bone.2013.08.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592179, KAKENHI-PROJECT-25670637
  • [Journal Article] Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling.2013

    • Author(s)
      Piao J, Tsuji K, Ochi H, Iwata M, Koga D, Okawa A, Morita S, Takeda S, Asou Y.
    • Journal Title

      Scientific Report

      Volume: october 23 Issue: 1 Pages: 3022-3022

    • DOI

      10.1038/srep03022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791565, KAKENHI-PROJECT-25462360, KAKENHI-PROJECT-25670637
  • [Journal Article] Comparison of different distal designs of femoral components and their effects on bone remodeling in 1-stage bilateral total hip arthroplasty2012

    • Author(s)
      Yamauchi Yuki, Jinno Tetsuya, Koga Daisuke, Asou Yoshinori, Morita Sadao, Okawa Atsushi
    • Journal Title

      J Arthroplasty

      Volume: 27巻 Pages: 1538-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659714
  • [Journal Article] Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model2012

    • Author(s)
      Hailati Aini, Hiroki Ochi, Munetaka Iwata, Atsushi Okawa, Daisuke Koga, Mutsumi Okazaki, Atsushi Sano, Yoshinori Asou
    • Journal Title

      PLoS ONE

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21591934
  • [Journal Article] Runx2 haploinsufficiency ameliorates the development of ossification of the posterior longitudinal ligament.2012

    • Author(s)
      Iwasaki M, Piao J, Kimura A, Sato S, Inose H, Ochi H, Asou Y, Shinomiya K, Okawa A, Takeda S.
    • Journal Title

      PLoS One

      Volume: 7 Issue: 8 Pages: e43372-e43372

    • DOI

      10.1371/journal.pone.0043372

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791627, KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791565
  • [Journal Article] 人工股関節全置換術における神経麻痺発生の危険因子の検討2012

    • Author(s)
      高田ちさと,古賀大介,神野哲也,麻生義則,山内裕樹,谷口直史,小谷野岳,佐々木亨,森田定雄,宗田大,大川淳
    • Journal Title

      Hip Joint

      Volume: 38巻 Pages: 448-452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659714
  • [Journal Article] Runx2 expression correlates with the degree of disc aging : a comparison between Magnetic Resonance Imaging and Runx2 expression2012

    • Author(s)
      Itoh H., Hara Y., Yagawa M., Kato T., Ochi H., Koga D., Okawa A., Shinomiya K., Asou Y.
    • Journal Title

      J Vet Med Sci

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21591934
  • [Journal Article] Evaluation of the association between runt-related transcription factor 2 expression and intervertebral disk aging in dogs.2012

    • Author(s)
      Itoh H, Hara Y, Tagawa M, Kato T, Ochi H, Koga D, Okawa A, Asou Y.
    • Journal Title

      Am J Vet Res

      Volume: Oct;73(10):1553-9. Pages: 1553-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Journal Article] 両側一期的人工股関節全置換術におけるドレーン留置の有用性に関する検討2012

    • Author(s)
      小谷野岳,神野哲也,麻生義則,古賀大介,谷口直史,高田ちさと,宗田大,大川淳,森田定雄,山内裕樹
    • Journal Title

      Hip Joint

      Volume: 38巻 Pages: 472-475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659714
  • [Journal Article] Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model2012

    • Author(s)
      Hailati Aini, Hiroki Ochi, Munetaka Iwata, Atsushi Okawa, Daisuke Koga, Mutsumi Okazaki, Atsushi Sano, Yoshinori Asou.
    • Journal Title

      PLoS ONE

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21591935
  • [Journal Article] Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model.2012

    • Author(s)
      Aini H, Ochi H, Iwata M, Okawa A, Koga D, Okazaki M, Sano A, Asou Y.
    • Journal Title

      PLoS One

      Volume: 7(5) Issue: 5 Pages: e37728-e37728

    • DOI

      10.1371/journal.pone.0037728

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-24791565
  • [Journal Article] Runx2 expression correlates with the degree of disc aging : a comparison between Magnetic Resonance Imaging and Runx2 expression2012

    • Author(s)
      Itoh H., Hara Y., Yagawa M., Kato T., Ochi H., Koga D., Okawa A., Shinomiya K., Asou Y.
    • Journal Title

      J Vet Med Sci

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21591935
  • [Journal Article] アプローチによる楔状テイパー型ステム増捻角の比較2011

    • Author(s)
      谷口直史,神野哲也,麻生義則,古賀大介,山内裕樹,宗田 大,大川 淳,森田定雄
    • Journal Title

      Hip Joint

      Volume: 37 Pages: 492-495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659714
  • [Journal Article] TNFR1 deficiency facilitates articular cartilage ossification and osteophyte formation2011

    • Author(s)
      Hailati A., Yamauchi Y., Ochi H., Koga D., Okawa A., Ogishima S., Okazaki M., Asou Y.
    • Journal Title

      Osteoarthritis and Cartilage suppl

    • Data Source
      KAKENHI-PROJECT-21591935
  • [Journal Article] Sirt6 regulates chondrocyte proliferation and differentiation during endochondral ossification2011

    • Author(s)
      Boku K., Ochi H., Tsuji K., Koga D., Okawa A., Morita S., Takeda S., Asou Y.
    • Journal Title

      Journal of Bone and Mineral Research suppl

    • Data Source
      KAKENHI-PROJECT-21591934
  • [Journal Article] Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages2010

    • Author(s)
      Shimizu S, Okuda N, Kato N, Rittling SR, Okawa A, Shinomiya K, Muneta T, Denhardt DT, Noda M, Tsuji K, Asou Y.
    • Journal Title

      Arthritis Rheum

      Volume: 62(5) Pages: 1329-37

    • NAID

      40019208000

    • Data Source
      KAKENHI-PROJECT-21591935
  • [Journal Article] The roles of TNFR1 in lipopolysaccharide-induced bone loss : dual effects of TNFR1 on bone metabolism via osteoclastogenesis and osteoblast survival2010

    • Author(s)
      Ochi, H ; Hara, Y ; Tagawa, M ; Shinomiya, K ; Asou, Y
    • Journal Title

      J Orthop Res

      Volume: 28(5) Pages: 657-63

    • Data Source
      KAKENHI-PROJECT-21591934
  • [Journal Article] 楔状テイパー型モノブロックステムによる前捻角の変化2010

    • Author(s)
      高田亮平(東京医科歯科大学医学部附属病院整形外科), 神野哲也, 麻生義則, 古賀大介, 山内裕樹, 森田定雄, 宗田大, 四宮謙一
    • Journal Title

      日本人工関節学会誌 40

      Pages: 642-643

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] 初回人工股関節全置換術における術後脱臼因子の解析2010

    • Author(s)
      古賀大介、神野哲也、麻生義則、山内裕樹、森田定雄、宗田大、四宮謙一
    • Journal Title

      日本人工関節学会誌 40

      Pages: 72-73

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] The roles of TNFR1 in lipopolysaccharide-induced bone loss : dual effects of TNFR1 on bone metabolism via osteoclastogenesis and osteoblast survival2010

    • Author(s)
      Ochi, H ; Hara, Y ; Tagawa, M ; Shinomiya, K ; Asou, Y
    • Journal Title

      J Orthop Res

      Volume: 28(5) Pages: 657-63

    • Data Source
      KAKENHI-PROJECT-21591935
  • [Journal Article] THA症例における静脈血栓症予防のための抗凝固薬の比較検討2010

    • Author(s)
      松村惠津子(東京医科歯科大学医学部附属病院整形外科), 神野哲也, 麻生義則, 古賀大介, 山内裕樹, 四宮謙一
    • Journal Title

      東日本整形災害外科学会雑誌 22

      Pages: 226-229

    • NAID

      10026919194

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages2010

    • Author(s)
      Shimizu S, Okuda N, Kato N, Rittling SR, Okawa A, Shinomiya K, Muneta T, Denhardt DT, Noda M, Tsuji K, Asou Y
    • Journal Title

      Arthritis Rheum

      Volume: 62(5) Pages: 1329-37

    • NAID

      40019208000

    • Data Source
      KAKENHI-PROJECT-21591934
  • [Journal Article] THA症例における静脈血栓症予防のためのフォンダパリヌクスナトリウムの使用経験2009

    • Author(s)
      宇土美於(東京医科歯科大学医学部附属病院整形外科), 神野哲也, 麻生義則, 古賀大介, 山内裕樹, 宗田大, 四宮謙一, 森田定雄
    • Journal Title

      Hip Joint(0389-3634) 35巻

      Pages: 545-548

    • NAID

      10026119664

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] Effects of compressive loading on biomechanical properties of disc and peripheral tissue in a rat tail model2009

    • Author(s)
      Nakamura T, Iribe T, Asou Y, Miyairi H, Ikegami K, Takakuda K.
    • Journal Title

      Eur Spine J

      Volume: 26

    • Data Source
      KAKENHI-PROJECT-21591935
  • [Journal Article] Effects of compressive loading on biomechanical properties of disc and peripheral tissue in a rat tail model2009

    • Author(s)
      Asou Y, et. al.
    • Journal Title

      Eur Spine J. 18(11)

      Pages: 1595-603

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] TNF-α-induced NF-κB signaling reverses age-related declines in VEGF induction and angiogenic activity in intervertebral disc tissues2009

    • Author(s)
      Asou Y, et. al.
    • Journal Title

      J Orthop.Res. 27(2)

      Pages: 229-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] Effects of compressive loading on biomechanical properties of disc and peripheral tissue in a rat tail model2009

    • Author(s)
      Nakamura T, Iribe T, Asou Y, Miyairi H, Ikegami K, Takakuda K
    • Journal Title

      Eur Spine J

    • Data Source
      KAKENHI-PROJECT-21591934
  • [Journal Article] 人工股関節置換術後の股関節内旋・外旋可動域2009

    • Author(s)
      神野哲也(東京医科歯科大学医学部附属病院整形外科), 古賀大介, 山内裕樹, 相澤純也, 麻生義則, 森田定雄, 宗田大, 四宮謙一
    • Journal Title

      日本人工関節学会誌 39巻

      Pages: 242-243

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] TNF-α-Induced NF-kB Signaling Reverses Age-Related Declines in VEGF Induction and Angiogenic Activity in Intervertebral Disc Tissues2009

    • Author(s)
      麻生義則, ほか
    • Journal Title

      Journal of Orthopaedics Research 27

      Pages: 229-235

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] Effects of compressive loading on biomechanical properties of disc and peripheral tissue in a rat tail model.2009

    • Author(s)
      麻生義則, ほか
    • Journal Title

      European Spine Journal 18

      Pages: 1595-1603

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] 人工股関節置換術における大腿骨側方および前方offsetの変化straight stemとanatomical stemの比較2009

    • Author(s)
      山内裕樹(東京医科歯科大学医学部附属病院整形外科), 神野哲也, 麻生義則, 古賀大介, 森田定雄, 宗田大, 四宮謙一
    • Journal Title

      Hip Joint 35巻

      Pages: 828-831

    • NAID

      10026120238

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] ハイドロキシアパタイト・コーティング人工股関節置換術の中・長期成績2009

    • Author(s)
      神野哲也(東京医科歯科大学医学部附属病院整形外科), 古賀大介, 山内裕樹, 麻生義則, 森田定雄, 長谷川清一郎, 松原正明, 宗田大, 四宮謙一
    • Journal Title

      日本人工関節学会誌 39巻

      Pages: 68-69

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] TNF-alpha-induced NF-kappaB signaling reverses age-related declines in VEGF induction and angiogenic activity in intervertebral disc tissues2009

    • Author(s)
      Ohba T, Haro H, Ando T, Wako M, Suenaga F, Asou Y, Koyama K, Hamada Y, Nakao A.
    • Journal Title

      J Orthop Res

      Volume: 27(2) Pages: 229-35

    • Data Source
      KAKENHI-PROJECT-21591935
  • [Journal Article] TNF-alpha-induced NF-kappaB signaling reverses age-related declines in VEGF induction and angiogenic activity in intervertebral disc tissues2009

    • Author(s)
      Ohba T, Haro H, Ando T, Wako M, Suenaga F, Asou Y, Koyama K, Hamada Y, Nakao A
    • Journal Title

      J Orthop Res

      Volume: 27(2) Pages: 229-35

    • Data Source
      KAKENHI-PROJECT-21591934
  • [Journal Article] 後側方進入による人工股関節置換術後の股関節内旋・外旋可動域2009

    • Author(s)
      神野哲也, 古賀大介, 山内裕樹, 麻生義則, 宗田大, 四宮謙一, 森田定雄, 相澤純也
    • Journal Title

      Hip Joint 35

      Pages: 181-184

    • NAID

      10026118967

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] 股関節疾患における股関節ブロックの有用性について2008

    • Author(s)
      山内裕樹, 神野哲也, 麻生義則, 古賀大介, 森田定雄, 宗田大, 四宮謙一
    • Journal Title

      Hip Joint 34巻

      Pages: 792-795

    • NAID

      10025762772

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] Enhanced type X collagen expression in the extruded nucleus pulposus of the chondrodystrophoid dog2008

    • Author(s)
      麻生 義則
    • Journal Title

      Journal of Veterinary Medical Science 70-1

      Pages: 37-42

    • NAID

      130000447240

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Journal Article] Enhanced type X collagen expression in the extruded nucleus pulposus of the chondrodystrophoid dog2008

    • Author(s)
      Asou Y, Shinomiya K, et. al.
    • Journal Title

      J.Vet.Med.Sci. 70(1)

      Pages: 37-42

    • NAID

      130000447240

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] Enhanced type X collagen expression in the extruded nucleus pulposus of the chondrodystrophoid dog.2008

    • Author(s)
      麻生義則、四宮謙一, ほか
    • Journal Title

      Journal of Veterinary Medical Science 70

      Pages: 37-42

    • NAID

      130000447240

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] 小皮切後側方進入による人工股関節全置換術2008

    • Author(s)
      神野哲也、古賀大介、麻生義則、山内裕樹、森田定雄、宗田大、四宮謙一
    • Journal Title

      日本人工関節学会誌 38巻

      Pages: 420-421

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] セメントレス臼蓋コンポーネント固定におけるスクリュー使用の影響:両側一期的THAにおける短期X線比較2008

    • Author(s)
      神野哲也、麻生義則、古賀大介、山内裕樹、森田定雄、宗田大、四宮謙一
    • Journal Title

      日本人工関節学会誌 38巻

      Pages: 622-623

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] Enhanced type X collagen expression in the extruded nucleus pulposus of the chondrodystrophoid dog.2008

    • Author(s)
      Itoh H. Asou Y et Al.
    • Journal Title

      Journal of Veterinary Medical Science 70(1)

      Pages: 37-42

    • NAID

      130000447240

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Journal Article] The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration : Findings in murine models and in human disease.2008

    • Author(s)
      Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S
    • Journal Title

      Arthritis Rheum. 58(9)

      Pages: 2764-2765

    • NAID

      40017274659

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] 人工股関節全置換術の周術期における理学的静脈血栓塞栓症予防2008

    • Author(s)
      宮崎恭子, 神野哲也, 麻生義則, 古賀大介, 山内裕樹, 森田定雄, 宗田大, 四宮謙一
    • Journal Title

      Hip Joint 34巻

      Pages: 690-692

    • NAID

      10025762577

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] 人工股関節全置換術における創縁皮膚および皮下脂肪の培養結果2008

    • Author(s)
      古賀大介, 神野哲也, 麻生義則, 山内裕樹, 宗田大, 四宮謙一, 森田定雄
    • Journal Title

      Hip Joint 34巻

      Pages: 738-741

    • NAID

      10025762682

    • Data Source
      KAKENHI-PROJECT-20591776
  • [Journal Article] Prevention of cartilage destruction with intraarticular osteoclastogenesis inhibitory factor/osteoprotegerin in a murine model of osteoarthritis.2007

    • Author(s)
      Shimizu S, Asou Y(2番目), Shinomiva K(6番目)ら計7人
    • Journal Title

      Arthritis Rheum 56

      Pages: 3358-65

    • NAID

      40016438510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591555
  • [Journal Article] Prevention of cartilage destruction with intraarticular osteoclastogenesis inhibitory factor/osteoprotegerin in a marinemodel of osteoarthritis.2007

    • Author(s)
      Shimizu S, Asou Y(2番目), Shinomiya K(6番目)ら計7人
    • Journal Title

      Arthritis Rheum 56

      Pages: 3358-65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591656
  • [Journal Article] Runx2 expression correlates with the degree of disc degeneration : a comparison between Magnetic Resonance Imaging and Runx2 expression.

    • Author(s)
      古賀大介、麻生義則、四宮謙一, ほか
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] Runx2 expression in the canine disc : cooperative expression with Matrix Metalloproteinase-13 in herniated discs

    • Author(s)
      Koga D, Shinomiya K., Asou Y, et. al.
    • Journal Title

      (in submit)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Journal Article] Runx2 expression in the canine disc : cooperative expression with Matrix Metalloproteinase-13 in hermiated discs

    • Author(s)
      Itoh H. Asou Y et.
    • Journal Title

      Journal of Orthopaedics Research (in submit)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Patent] ブドウ種子抽出物を含む更年期障害改善剤2023

    • Inventor(s)
      麻生義則, ほか
    • Industrial Property Rights Holder
      株式会社エーゼット
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] PAI-1 accelerates sarcopenia and ageing-related osteoporosis.2019

    • Author(s)
      Aidehamu Aihemaiti, Alkebaier Aobulikasimu,Takuya Oyaizu,Hiroki Ochi,Shingo Sato,Kunikazu Tsuji,Toshio Miyata,Atsushi Okawa,Yoshinori Asou
    • Organizer
      米国骨代謝学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19604
  • [Presentation] PAI-1 accelerates sarcopenia and ageing-related osteoporosis.2019

    • Author(s)
      Aidehamu Aihemaiti, Naoki Yamamoto, Alkebaier Aobulikasimu, Takuya Oyaizu,Hiroki Ochi,Shingo Sato, Kunikazu Tsuji, Toshio Miyata,Atsushi Okawa, Yoshinori Asou
    • Organizer
      米国骨代謝学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11000
  • [Presentation] Osteocyte Sirt6 has crucial roles in bone and phosphate metabolism through senescence- dependent and -independent manner2019

    • Author(s)
      Alkebaier Aobulikasimu*1 , Hiroki Ochi1 , Jinying Piao1 , Shingo Sato1 , Kunikazu Tsuji2 , Atsushi Okawa1 , Yoshinori Asou1
    • Organizer
      米国骨代謝学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09096
  • [Presentation] Osteocyte Sirt6 has crucial roles in bone and phosphate metabolism through senescence- dependent and -independent manner2019

    • Author(s)
      Alkebaier Aobulikasimu*1 , Hiroki Ochi1 , Jinying Piao1 , Shingo Sato1 , Kunikazu Tsuji2 , Atsushi Okawa1 , Yoshinori Asou1
    • Organizer
      米国骨代謝学会(国際学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] PAI-1はロコモティブシンドローム、サルコペニアを加速する。2019

    • Author(s)
      アディハム アハマット1)  アクバル アブルカスム 越智 広樹  山本 尚輝  小柳津 卓哉 宮田 敏男 佐藤 信吾  畑 裕  辻 邦和  大川 淳  麻生 義則
    • Organizer
      日本整形外科基礎学会
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] 骨細胞Sirt6による骨代謝、リン代謝制御機構2019

    • Author(s)
      Alkebaier Aobulikasimu、越智広樹、朴金瑛、佐藤信吾、辻邦和、大川淳、麻生義則
    • Organizer
      日本整形外科基礎学会
    • Data Source
      KAKENHI-PROJECT-18K09096
  • [Presentation] PAI-1はロコモティブシンドローム、サルコペニアを加速する。2019

    • Author(s)
      アディハム アハマット  アクバル アブルカスム  越智広樹 山本尚輝  小柳津卓哉  宮田敏男 佐藤信吾  畑裕  辻邦和  大川淳  麻生義則
    • Organizer
      日本整形外科基礎学会
    • Data Source
      KAKENHI-PROJECT-18K09096
  • [Presentation] PAI-1阻害は筋骨格系組織の退行性変化を予防する。2019

    • Author(s)
      アディハム アハマット1)  アクバル アブルカスム 越智 広樹  山本 尚輝  小柳津 卓哉 宮田 敏男 佐藤 信吾  畑 裕  辻 邦和  大川 淳  麻生 義則
    • Organizer
      骨関節フォーラム
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] 骨細胞Sirt6による骨代謝、リン代謝制御機構2019

    • Author(s)
      Alkebaier Aobulikasimu、越智広樹、朴金瑛、佐藤信吾、辻邦和、大川淳、麻生義則
    • Organizer
      日本整形外科基礎学会
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] PAI-1 accelerates sarcopenia and ageing-related osteoporosis.2019

    • Author(s)
      Aidehamu Aihemaiti,Naoki Yamamoto,Alkebaier Aobulikasimu,Hiroki Ochi, Shingo Sato,Kunikazu Tsuji,Toshio Miyata,Atsushi Okawa,Yoshinori Asou
    • Organizer
      米国骨代謝学会(国際学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] 骨細胞Sirt6による骨代謝制御機構2018

    • Author(s)
      Alkebaier Aobulikasimu、Zulipiya Aibibula、朴金瑛、金光文、越智広樹、佐藤信吾、大川淳、麻生義則
    • Organizer
      骨関節フォーラム
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] 骨細胞のSirt6はSOST発現を介して骨代謝を制御する2018

    • Author(s)
      Alkebaier Aobulikasimu*1, Zulipiya Aibibula1, Jinying Piao1, Shingo Sato2, Hiroki Ochi2, Kunikazu Tsuji3, Atsushi Okawa1, Yoshinori Asou1
    • Organizer
      日本整形外科基礎学会
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] Osteocyte Sirt6 has crucial roles in bone and phosphate metabolism2018

    • Author(s)
      Alkebaier Aobulikasimu*1, Zulipiya Aibibula1, Jinying Piao1, Shingo Sato2, Hiroki Ochi2, Kunikazu Tsuji3, Atsushi Okawa1, Yoshinori Asou1
    • Organizer
      annual meeting for american society of bone and mineral research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02920
  • [Presentation] 新規PAI-1阻害薬は閉経後骨粗鬆症モデルの骨密度を回復させる2017

    • Author(s)
      金 光文, 朴 英瑛, Aobulikasimu Alkebaier, Zulipiya Aibibula, 段 孝, 市村 敦彦, 赤堀 浩司, 宮田 敏男, 越智 広樹, 佐藤 信吾, 大川 淳, 麻生 義則
    • Organizer
      日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-15K15541
  • [Presentation] 新規PAI-1阻害剤はマウス骨髄除去モデルにおいて骨形成を促進する2017

    • Author(s)
      Aobulikasimu Alkebaier, 金 光文, 朴 金瑛, Zulipiya Aibibula, 段 孝, 市村 敦彦, 宮田 敏男, 越智 広樹, 佐藤 信吾, 大川 淳, 麻生 義則
    • Organizer
      日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] 新規PAI-1阻害薬は閉経後骨粗鬆症モデルの骨密度を回復させる2017

    • Author(s)
      金 光文, 朴 英瑛, Aobulikasimu Alkebaier, Zulipiya Aibibula, 段 孝, 市村 敦彦, 赤堀 浩司, 宮田 敏男, 越智 広樹, 佐藤 信吾, 大川 淳, 麻生 義則
    • Organizer
      日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] 新規PAI-1阻害剤はマウス骨髄除去モデルにおいて骨形成を促進する2017

    • Author(s)
      Aobulikasimu Alkebaier, 金 光文, 朴 金瑛, Zulipiya Aibibula, 段 孝, 市村 敦彦, 宮田 敏男, 越智 広樹, 佐藤 信吾, 大川 淳, 麻生 義則
    • Organizer
      日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-15K15541
  • [Presentation] PAI-1 inhibitor treatment attenuates bone loss by stimulating bone formation in a mouse model of postmenopausal osteporosis2017

    • Author(s)
      Guangwen Jin、Jinying Piao、Zulipiya Aibibula、Daisuke Koga、Hiroki Ochi、Kunikazu Tsuji、Toshio Miyata、Atsushi Okawa、Yoshinori Asou
    • Organizer
      Annual meeting for American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11000
  • [Presentation] 新規PAI-1阻害薬は閉経後骨粗鬆症モデルの骨密度を回復させる2017

    • Author(s)
      金 光文(東京医科歯科大学 大学院整形), 朴 英瑛, 段 孝, 市村 敦彦, 赤堀 浩司, 宮田 敏男, 越智 広樹, 佐藤 信吾, 大川 淳, 麻生 義則
    • Organizer
      日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17K11000
  • [Presentation] 新規PAI-1阻害剤はマウス骨髄除去モデルにおいて骨形成を促進する2017

    • Author(s)
      alkebaier・aobulikasimu、金光文、、Zulipiya・Aibibula、朴金瑛、越智広樹、宮田敏男、大川淳、麻生義則
    • Organizer
      日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17K11000
  • [Presentation] PAI-1 inhibitor treatment attenuates bone loss by stimulating bone formation in a mouse model of postmenopausal osteporosis2017

    • Author(s)
      金光文、朴金瑛、ゾリビア・エビブラ、アクバル・アブリカスム、古賀大介、越智広樹、辻邦和、宮田敏男、大川淳、麻生義則
    • Organizer
      Annual meeting for American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] 閉経後骨粗鬆症モデルにおいて新規PAI-1阻害薬は骨形成を刺激して骨密度を回復させる2017

    • Author(s)
      麻生 義則, 金 光文, アブルカスム・アクバル , ゾリビア・エビブラ , 朴 金瑛, 越智 広樹, 宮田 敏男, 大川 淳
    • Organizer
      日本骨粗鬆症学会
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] 閉経後骨粗鬆症モデルにおいて新規PAI-1阻害薬は骨形成を刺激して骨密度を回復させる2017

    • Author(s)
      麻生義則、金光文、alkebaier・aobulikasimu、Zulipiya・Aibibula、朴金瑛、越智広樹、宮田敏男、大川淳
    • Organizer
      日本骨粗鬆症学会
    • Data Source
      KAKENHI-PROJECT-17K11000
  • [Presentation] Xanthine oxidase inhibitor febuxostat attenuate high fat diet-induced osteoarthritis.2016

    • Author(s)
      Zulipiya Aibibula*2, Maierhaba Ailixiding*1, Jinying Piao2 , Daisuke Koga2, Atsushi Okawa2, Yoshinori Asou2
    • Organizer
      Annual meeting for Orthopaedics Research Society
    • Place of Presentation
      フロリダ州オーランド(米国)
    • Year and Date
      2016-03-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462361
  • [Presentation] 高脂肪食誘導性変形性膝関節症におけるキサンチンオキシダーゼ(XOR)の機能解析2016

    • Author(s)
      Zulipiya Aibibula、Maierhaba Ailixiding、朴 金瑛,  金光文、古賀 大介, 大川 淳、 麻生 義則
    • Organizer
      日本整形外科基礎学術集会
    • Place of Presentation
      福岡国際会議場(福岡県 福岡市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K15541
  • [Presentation] Xanthine oxidase inhibitor febuxostat attenuate high fat diet-induced osteoarthritis.2016

    • Author(s)
      Zulipiya Aibibula*2, Maierhaba Ailixiding*1, Jinying Piao2 , Daisuke Koga2, Atsushi Okawa2, Yoshinori Asou2
    • Organizer
      annual meeting of Orthopaedic Research Society
    • Place of Presentation
      フロリダ州オーランド(米国)
    • Year and Date
      2016-03-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15541
  • [Presentation] メタボリックOAにおけるキサンチンオキシダーゼの機能解析2015

    • Author(s)
      ゾリビア アビブラ1)、マルハバ アルシデン2)、朴金瑛1)、金光文1)、大川淳1)、麻生義則
    • Organizer
      東京骨関節フォーラム
    • Place of Presentation
      昭和大学(東京都品川区)
    • Year and Date
      2015-07-04
    • Data Source
      KAKENHI-PROJECT-15K15541
  • [Presentation] メタボリックシンドロームと変形性膝関節症のクロストークにおけるサーチュイン遺伝子Sirt6の機能解析2015

    • Author(s)
      麻生 義則, Maierhaba Ailixiding, Zulipiya Aibibula, 朴 金瑛, 古賀 大介, 大川 淳, 森田 定雄
    • Organizer
      第30回日本整形外科基礎学術集会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-25462361
  • [Presentation] メタボリックシンドロームと変形性膝関節症のクロストークにおけるサーチュイン遺伝子Sirt6の機能解析2015

    • Author(s)
      麻生 義則, Maierhaba Ailixiding, Zulipiya Aibibula, 朴 金瑛, 古賀 大介, 大川 淳, 森田 定雄
    • Organizer
      日本整形外科基礎学会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] セメントレス人工股関節全置換術後の大腿骨脆弱性骨折の特徴2015

    • Author(s)
      平尾昌之、神野哲也、木村晶理、高田亮平、麻生義則、森田定雄、宗田大、大川淳
    • Organizer
      日本股関節学会
    • Place of Presentation
      グランフロント大阪(大阪府大阪市)
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-25462360
  • [Presentation] 人工股関節全置換術におけるトラネキサム酸静脈内投与の効果と凝固線溶系に与える影響(原著論文)2015

    • Author(s)
      平尾 昌之, 神野 哲也, 古賀 大介, 高田 亮平, 瀬川 裕子, 星野 ちさと, 麻生 義則, 森田 定雄, 宗田 大, 大川 淳
    • Organizer
      日本股関節学会
    • Place of Presentation
      グランフロント大阪(大阪府大阪市)
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] 前方進入法と前側方進入法による人工股関節全置換術術後早期CTにおける股関節外転筋断面積の比較検討2015

    • Author(s)
      高田 亮平, 神野 哲也, 古賀 大介, 平尾 昌之, 星野 ちさと, 麻生 義則, 森田 定雄, 宗田 大, 大川 淳
    • Organizer
      日本整形外科学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] 高脂肪食誘導性変形性膝関節症におけるキサンチンオキシダーゼ(XOR)の機能解析2015

    • Author(s)
      麻生 義則, Zulipiya Aibibula, Maierhaba Ailixiding, 朴 金瑛, 金 光文, 古賀 大介, 大川 淳
    • Organizer
      日本整形外科基礎学会)
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-15K15541
  • [Presentation] 高脂肪食誘導性変形性膝関節症におけるキサンチンオキシダーゼ(XOR)の機能解析2015

    • Author(s)
      麻生 義則, Zulipiya Aibibula, Maierhaba Ailixiding, 朴 金瑛, 金 光文, 古賀 大介, 大川 淳
    • Organizer
      第30回日本整形外科基礎学術集会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-25462361
  • [Presentation] 人工股関節全置換術におけるトラネキサム酸静脈内投与の効果と凝固線溶系に与える影響2015

    • Author(s)
      平尾 昌之, 神野 哲也, 古賀 大介, 高田 亮平, 瀬川 裕子, 星野 ちさと, 麻生 義則, 森田 定雄, 宗田 大, 大川 淳
    • Organizer
      第42回日本股関節学会
    • Place of Presentation
      グランフロント大阪(大阪府大阪市)
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-25462361
  • [Presentation] セメントレス人工股関節全置換術後の大腿骨脆弱性骨折2015

    • Author(s)
      平尾 昌之, 神野 哲也, 古賀 大介, 高田 亮平, 麻生 義則, 森田 定雄, 宗田 大, 大川 淳
    • Organizer
      日本整形外科学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] サーチュイン遺伝子Sirt6による軟骨代謝制御2012

    • Author(s)
      麻生 義則
    • Organizer
      東京医科歯科大学第4回硬組織疾患ゲノムセンターセミナー
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Presentation] 短期高脂肪食負荷に対するマウス膝関節の初期組織学的反応2012

    • Author(s)
      Munetaka Iwata, Hiroki Ochi, Yasushi Hara, Daisuke Koga, Masahiro Tagawa, Atsushi Okawa, Yoshinori Asou
    • Organizer
      日本整形外科学会基礎学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Presentation] サーチュイン遺伝子Sirt6による軟骨代謝制御2012

    • Author(s)
      朴金瑛 辻邦和 越智広樹 森田定雄 古賀大介 大川淳 竹田秀 麻生義則
    • Organizer
      日本整形外科学会基礎学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Presentation] 短期高脂肪食負荷によるマウス変形性膝関節症モデルの樹立2011

    • Author(s)
      岩田宗峻,越智広樹,原康,多川政弘,古賀大介,大川淳,麻生義則
    • Organizer
      東京骨関節フォーラム
    • Data Source
      KAKENHI-PROJECT-21591935
  • [Presentation] Sirt6 regulates chondrocyte proliferation and differentiation during endochondral ossification2011

    • Author(s)
      Boku K., Ochi H., Tsuji K., Koga D., Okawa A., Morita S., Takeda S., Asou Y.
    • Organizer
      Annual meeting for American society for bone and mineral research
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] サーチュイン遺伝子Sirt6による軟骨代謝制御2011

    • Author(s)
      麻生義則, ほか
    • Organizer
      東京骨関節フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2011-08-06
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] SHORT TERM HIGH-FAT DIET INDUCES OSTEOPHYTE FORMATION, APOPTOSIS AND DEGENERATION OF ARTICULAR CHONDROCYTE IN MURINE KNEE JOINT2011

    • Author(s)
      古賀大介、麻生義則, ら
    • Organizer
      OsteoArthritis Research Society International (OARSI) 2011 World Congress on Osteoarthritis
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21591935
  • [Presentation] Sirt6 Regulates Chondrocyte Proliferation and Differentiation during Endochondral Ossification2011

    • Author(s)
      麻生義則, ほか
    • Organizer
      American Society for Bone and Mineral Research (ASBMR) 2011 Annual Meeting
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2011-09-19
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] サーチュイン遺伝子Sirt6による軟骨代謝制御2011

    • Author(s)
      朴金瑛,辻邦和,古賀大介,森田定雄,大川淳,竹田秀,麻生義則
    • Organizer
      東京骨関節フォーラム
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] TNFR1 deficiency facilitates articular cartilage ossification and osteophyte formation2011

    • Author(s)
      Hailati A., Yamauchi Y., Ochi H., Koga D., Okawa A., Ogishima S., Okazaki M., Asou Y.
    • Organizer
      OARSI world congress on osteoarthritis
    • Data Source
      KAKENHI-PROJECT-21591935
  • [Presentation] TNFR1 deficiency facilitates articular cartilage ossification and osteophyte formation2011

    • Author(s)
      Hailati A., Yamauchi Y., Ochi H., Koga D., Okawa A., Ogishima S., Okazaki M., Asou Y
    • Organizer
      OARSI world congress on osteoarthritis
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] 短期高脂肪食負荷によるマウス変形性膝関節症モデルの樹立2011

    • Author(s)
      岩田宗峻,越智広樹,原康,多川政弘,古賀大介,大川淳,麻生義則
    • Organizer
      東京骨関節フォーラム
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] Short term high-fat diet induces osteophyte formation apoptosis and degeneration of articular chondrocyte in murine knee joint2011

    • Author(s)
      Iwata M, Ochi H, Hara Y, Koga D, Tagawa M, Okawa A, Asou Y
    • Organizer
      OARSI world congress on osteoarthritis
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] サーチュイン遺伝子Sirt6による軟骨代謝制御2011

    • Author(s)
      朴金瑛,辻邦和,古賀大介,森田定雄,大川淳,竹田秀,麻生義則
    • Organizer
      東京骨関節フォーラム
    • Data Source
      KAKENHI-PROJECT-21591935
  • [Presentation] TNFR1 DEFICIENCY FACILITATES ARTICULAR CARTILAGE OSSIFICATION AND OSTEOPHYTE FORMATION2011

    • Author(s)
      古賀大介、麻生義則, ら
    • Organizer
      OsteoArthritis Research Society International (OARSI) 2011 World Congress on Osteoarthritis
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21591935
  • [Presentation] Chondroprotective effects of procyanidin in murine articular chondrocytes2010

    • Author(s)
      Aini Hailati,麻生義則,越智弘樹,古賀大介,加藤剛,大川淳,佐野淳,岡崎睦
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21591934
  • [Presentation] 両側一期的人工股関節置換術におけるステムデザインの違いによる骨リモデリング様式と骨密度分布の違いについての検討2010

    • Author(s)
      山内裕樹, 神野哲也, 麻生義則, 古賀大介, 森田定雄, 宗田大, 大川淳, 四宮謙一
    • Organizer
      日本整形外科学会雑誌84:S726
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] THAのさらなる耐久性の向上を目指してハイドロキシアパタイトコーティングカップを用いた人工股関節置換術の中長期成績2010

    • Author(s)
      神野哲也, 古賀大介, 山内裕樹, 麻生義則, 松原正明, 長谷川清一郎, 宗田大
    • Organizer
      日本関節病学会誌29:319
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 関節リウマチに対するセメントレス人工股関節置換術後の合併症2010

    • Author(s)
      神野哲也, 古賀大介, 山内裕樹, 麻生義則, 森田定雄, 宗田大
    • Organizer
      日本関節病学会誌29:338
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] Chondroprotective effects of procyanidin in murine articular chondrocytes2010

    • Author(s)
      Aini Hailati,麻生義則,越智弘樹,古賀大介,加藤剛,大川淳,佐野淳,岡崎睦
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21591935
  • [Presentation] 大腿骨コンポーネント形状の違いが人工股関節置換術周術期の凝固線溶系マーカー値に与える影響2010

    • Author(s)
      古賀大介, 神野哲也, 麻生義則, 山内裕樹, 森田定雄, 宗田大, 四宮謙一
    • Organizer
      日本整形外科学会雑誌84:S133
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 近位ハイドロキシアパタイトコーティング・ストレートステムの中・長期成績2009

    • Author(s)
      神野哲也, 古賀大介, 山内裕樹, 麻生義則, 森田定雄, 長谷川清一郎, 松原正明, 宗田大, 四宮謙一
    • Organizer
      第82回日本整形外科学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] Leptin regulation of articular chondrocyte is independent of mechanical stress or sympathetic nerve stimuraltion.2009

    • Author(s)
      加藤剛、麻生義則, ほか
    • Organizer
      米国骨代謝学会
    • Place of Presentation
      米国・デソバー
    • Data Source
      KAKENHI-PROJECT-19591754
  • [Presentation] Leptin regulation of articular chondrocyte is independent of mechanical stress or sympathetic nerve stimuraltion2009

    • Author(s)
      T. Kato, H. OCHI, S. Takeda, K. Tsuji, D. Koga, Y. Hara, M. Tagawa, K. Shinomiya, Y. Asou
    • Organizer
      米国骨代謝学会
    • Data Source
      KAKENHI-PROJECT-19591754
  • [Presentation] Leptin regulation of articular chondrocyte is independent of mechanical stress or sympathetic nerve stimuraltion.2009

    • Author(s)
      古賀、麻生、竹田、四宮, ほか
    • Organizer
      米国骨代謝学会
    • Place of Presentation
      米国
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Presentation] THA症例におけるフォンダパリヌクスナトリウムの使用経験2008

    • Author(s)
      宇土美於、神野哲也、麻生義則、古賀大介、山内裕樹、森田定雄、宗田大、四宮謙一
    • Organizer
      第35回日本股関節学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] セメントレス臼蓋コンポーネント固定におけるスクリュー使用の影響:両側一期的THAにおける短期X線比較2008

    • Author(s)
      神野哲也、麻生義則、古賀大介、山内裕樹、森田定雄、宗田大、四宮謙一
    • Organizer
      第38回日本人工関節学会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] セメントレス人工股関節置換術に対するポリエチレンライナー再置換術の短中期成績2008

    • Author(s)
      古賀大介、神野哲也、麻生義則、山内裕樹、森田定雄、宗田大、四宮謙一
    • Organizer
      第38回日本人工関節学会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 人工股関節全置換術後の静脈血栓塞栓症に対する理学的予防法の有用性2008

    • Author(s)
      宮崎恭子, 神野哲也, 麻生義則, 古賀大介, 山内裕樹, 森田定雄, 宗田大, 四宮謙一
    • Organizer
      日本整形外科学会雑誌(0021-5325)82巻2号PageS202
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 小皮切後側方侵入による人工股関節全置換術2008

    • Author(s)
      神野哲也、古賀大介、麻生義則、山内裕樹、森田定雄、宗田大、四宮謙一
    • Organizer
      第38回日本人工関節学会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 両側THAにおける2種の近位固定型ステムのX線学的検討2008

    • Author(s)
      山内裕樹、神野哲也、麻生義則、古賀大介、森田定雄、宗田大、四宮謙一
    • Organizer
      第38回日本人工関節学会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 後側方進入による人工股関節置換術後の内旋・外旋可動域2008

    • Author(s)
      神野哲也、古賀大介、山内裕樹、相澤純也、麻生義則、宗田大、森田定雄、四宮謙一
    • Organizer
      第35回日本股関節学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 人工股関節全置換術中に採取した創縁皮膚および皮下脂肪の培養結果2008

    • Author(s)
      古賀大介, 神野哲也, 麻生義則, 山内裕樹, 森田定雄, 宗田大, 四宮謙一
    • Organizer
      日本整形外科学会雑誌(0021-5325)82巻2号PageS201
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 人工股関節置換術周術期でのD-Dimer値の推移について-片側手術例と両側一期的手術例の比較検討2008

    • Author(s)
      鈴木英嗣、神野哲也、麻生義則、古賀大介、山内裕樹、宮崎恭子、森田定雄、宗田大、四宮謙一
    • Organizer
      第38回日本人工関節学会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 両側同時THAにおけるStryker Super Secur-fit stemとCentPillar stemの短期成績比較2008

    • Author(s)
      山内裕樹, 神野哲也, 麻生義則, 古賀大介, 森田定雄, 宗田大, 四宮謙一
    • Organizer
      日本整形外科学会雑誌(0021-5325)82巻2号PageS196
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] Effects of additional screw fixation on cementless acetabular cup fixation : Short-term radiographical comparison in bilateral one-stage total hip arthroplasty2008

    • Author(s)
      Jinno T, Asou Y, Koga D, Yamauchi Y, Otabe K, Morita S, Muneta T, Shinomiya K
    • Organizer
      日本整形外科学会雑誌(0021-5325)82巻2号PageS298
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 小皮切後側方進入による人工股関節全置換術2008

    • Author(s)
      神野哲也、古賀大介、麻生義則、山内裕樹、森田定雄、宗田大、四宮謙一
    • Organizer
      第38回日本人工関節学会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20591776
  • [Presentation] 変性椎間板におけるMMP-13と転写因子Runx2の発現解析2007

    • Author(s)
      麻生義則、竹田秀、四宮謙一, ほか
    • Organizer
      日本整形外科基礎学術集会
    • Place of Presentation
      国内
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Presentation] 変性椎間板におけるMMP-13と転写因子Runx2の発現解析2007

    • Author(s)
      麻生 義則
    • Organizer
      日本整形外科基礎学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2007-10-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Presentation] Runx2 expression in the canine disc : cooperative expression with Matrix Metalloproteinase-13 in herniated discs2007

    • Author(s)
      Asou Y, Takeda S, et. al.
    • Organizer
      Annual orthopaedic research meeting of the Japanese orthopaedic
    • Place of Presentation
      Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Presentation] 犬の椎間板逸脱症罹患症例の逸脱椎間板物質におけるRunx2の発現について2006

    • Author(s)
      麻生義則、竹田秀、四宮謙一, ほか
    • Organizer
      日本獣医畜産大学学術交流会
    • Place of Presentation
      国内
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Presentation] Runx2 Expression correlates with Magnetic Resonance Imaging intervertebral disc degeneration2006

    • Author(s)
      麻生 義則
    • Organizer
      米国骨代謝学会
    • Place of Presentation
      米国フィラデルフィア
    • Year and Date
      2006-09-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Presentation] Runx2 Expression correlates with Magnetic Resonance Imaging intervertebral disc degeneration2006

    • Author(s)
      Asou Y, Shinomiya K, et. al.
    • Organizer
      Annual meeting of American society for bone and mineral research
    • Place of Presentation
      US
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Presentation] Runx2 expression is enhanced in the process of canine intervertebral disc degeneration2006

    • Author(s)
      Yoshinori Asou et. al
    • Organizer
      Annual meeting of Orthopaedic Reserch Society
    • Place of Presentation
      Chicago, US
    • Year and Date
      2006-03-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Presentation] Runx2 Expre'ssion correlates with Magnetic Resonance Imaging intervertebral disc degeneration2006

    • Author(s)
      Yoshinori Asou et. al
    • Organizer
      Annual meeting of American society for bone and mineral research
    • Place of Presentation
      Philadelphia, US
    • Year and Date
      2006-09-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Presentation] Runx2 expression is enhanced in the process of intervertebral disc degeneration2006

    • Author(s)
      麻生 義則
    • Organizer
      米国整形外科基礎学会
    • Place of Presentation
      米国シカゴ
    • Year and Date
      2006-03-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Presentation] Runx2 Expression correlates with Magnetic Resonance Imaging intervertebral disc degeneration.2006

    • Author(s)
      麻生義則、竹田秀、四宮謙一, ほか
    • Organizer
      骨代謝学会
    • Place of Presentation
      米国
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Presentation] Degeneration of intervertebral discs by compression2006

    • Author(s)
      Asou Y, et. al.
    • Organizer
      JSME Conference on Frontiers in Bioengineering
    • Place of Presentation
      Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591623
  • [Presentation] Enhanced Runx2 Expression Is Accompanied with Degenerative Changes in Canine Intervertebral Disc2005

    • Author(s)
      麻生 義則
    • Organizer
      米国骨代謝学会
    • Place of Presentation
      米国テネシー州ナッシュビル
    • Year and Date
      2005-09-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Presentation] Enhanced Runx2 Expression Is Accompanied with Degenerative Changes in Canine Intervertebral Disc2005

    • Author(s)
      Yoshinori Asou et. al
    • Organizer
      Annual meeting of American society for bone and mineral research
    • Place of Presentation
      Nashville, US
    • Year and Date
      2005-09-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591553
  • [Presentation] Sirt6 regulate proliferation and differentiation of the postnatal growth plate chondrocyte via Ihh signaling.

    • Author(s)
      Jinying Piao1, Kunikazu Tsuji2, Hiroki Ochi3, Sadao Morita1, Daisuke Koga4, Atsushi Okawa4, Shu Takeda5, Yoshinori Asou4
    • Organizer
      Annual meeting of American Society for Bone and Mineral Research
    • Place of Presentation
      Baltimore USA
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Presentation] サーチュイン遺伝子Sirt6による軟骨代謝制御機構の解析

    • Author(s)
      朴 金瑛, 辻 邦和, 越智 広樹, 古賀 大介, 大川 淳, 竹田 秀, 麻生 義則
    • Organizer
      日本整形外科学会基礎学会
    • Place of Presentation
      鹿児島(城山観光ホテル)
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] サーチュイン遺伝子Sirt6による軟骨代謝制御機構の解析

    • Author(s)
      朴金瑛1 辻邦和2 越智広樹3 古賀大介1 大川淳1 竹田秀3 麻生義則1
    • Organizer
      日本整形外科学会基礎学会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Presentation] The distinct role of the infrapatellar fat pad in a murine high-fat diet-induced osteoarthritis model.

    • Author(s)
      Munetaka Iwata1, Hiroki Ochi2, Yasushi Hara1, Masahiro Tagawa1, Daisuke Koga3, Atsushi Okawa3, Yoshinori Asou3
    • Organizer
      Annual meeting of American Society for Bone and Mineral Research
    • Place of Presentation
      Baltimore USA
    • Data Source
      KAKENHI-PROJECT-24592257
  • [Presentation] 高脂肪食負荷による膝蓋下脂肪体肥大化は力学的負荷とは独立して変形性膝関節症を惹起する

    • Author(s)
      岩田宗峻, 越智 広樹, 原 康, 古賀 大介, 大川 淳, 麻生 義則
    • Organizer
      日本整形外科学会基礎学会
    • Place of Presentation
      鹿児島(城山観光ホテル)
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-26293332
  • [Presentation] The distinct role of the infrapatellar fat pad in a murine high-fat diet-induced osteoarthritis model.

    • Author(s)
      Munetaka Iwata1, Hiroki Ochi2, Yasushi Hara1, Masahiro Tagawa1, Daisuke Koga3, Atsushi Okawa3, Yoshinori Asou3
    • Organizer
      Annual meeting of American Society for Bone and Mineral Research
    • Place of Presentation
      Baltimore USA
    • Data Source
      KAKENHI-PROJECT-25462361
  • [Presentation] 高脂肪食負荷による膝蓋下脂肪体肥大化は力学的負荷とは独立して変形性膝関節症を惹起する。

    • Author(s)
      岩田宗峻1 越智広樹2 原康1 多川政弘1 古賀大介3 大川淳3 麻生義則3
    • Organizer
      日本整形外科学会基礎学会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-24592257
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