MORIMOTO Konosuke 森本浩之輔

Researcher Number	50346970
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 熱帯医学研究所, 特定教授
Affiliation (based on the past Project Information) *help	2023: 長崎大学, 熱帯医学研究所, 教授 2022: 長崎大学, 熱帯医学研究所, 特定教授 2020 – 2021: 長崎大学, 熱帯医学研究所, 教授 2012 – 2019: 長崎大学, 熱帯医学研究所, 准教授 2008 – 2010: Nagasaki University, 熱帯医学研究所, 准教授
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Basic Section 54030:Infectious disease medicine-related Except Principal Investigator Respiratory organ internal medicine / Epidemiology and preventive medicine
Keywords	Principal Investigator 炎症終息 / 肺胞マクロファージ / efferocytosis / 小胞体ストレス / アポトーシス / インフルエンザ様症状 / サーベイランス / 病原体サーベイランス / 急性呼吸器感染症 / 高齢者 … More / 肺炎球菌保菌 / 高齢者肺炎 / 肺炎 / 保菌 / 肺炎球菌 / 呼吸器内科学 / effercocytosis / RhoA / ER stress / apoptosis / 急性肺障害 / 肺線維症 / 組織修復 / 肺気腫 / 慢性肺疾患 / 閉塞性肺疾 / 閉塞性肺疾患 … More Except Principal Investigator 成人肺炎 / 呼吸器感染症 / 肺炎球菌血清型 / 肺炎球菌性肺炎 / マルチプレックスPCR / 血清型 / 肺炎球菌 / サーファクタント / 遺伝性疾患 / ラメラ体 / 肺胞上皮細胞 / 肺線維症 / 間質性肺炎 / SP-C / iPS細胞 / 敗血症 / 急性肺障害 / Rhoキナーゼ / ROCK / ARDS / 敗血症性ショック / 血管透過性亢進 / セロトニン Less

パンデミック後を見据えた急性呼吸器感染症サーベイランスの構築Principal Investigator
- Principal Investigator
  
  森本浩之輔
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Nagasaki University
高齢者肺炎における肺炎球菌保菌調査の構築と分析Principal Investigator
- Principal Investigator
  
  森本浩之輔
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nagasaki University
Analysis of protective mechanism of acute lung injury via serotonin transporter/serotonin blockade
- Principal Investigator
  
  TANAKA Takeshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagasaki University
Can endoplasmic reticulum stress on alveolar macrophages be a therapeutic target for lung fibrosis?Principal Investigator
- Principal Investigator
  
  MORIMOTO Konosuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagasaki University
Study for pulmonary fibrosis using iPS cells
- Principal Investigator
  
  Isao Ito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Deveropement of nano-fludic technology based PCR for epidemiology of pneumococcus serotypes
- Principal Investigator
  
  FURUMOTO Akitsugu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Nagasaki University
The impact of ER stress on resolution of inflammation and tissue repair in lungPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Konosuke
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagasaki University
Efferocytosis as a novel therapeutic target of emphysemaPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Konosuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagasaki University

All 2019 2017 2016 2015 2014 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Impairment of tissue repair in pneumonia due to β-cell deficiency: role of endoplasmic reticulum stress in alveolar macrophages.2019
- Author(s)
  Yamashita Y, Kuroki R, Takaki M, Tanaka T, Senba M, Morimoto K, Amano H.
- Journal Title
  
  BMC Res Notes
  
  Volume: 12 Issue: 1 Pages: 160-160
- DOI
  10.1186/s13104-019-4209-0
- NAID
  120006987760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09545
[Journal Article] The burden and etiology of community-onset pneumonia in the aging Japanese population: a multicenter prospective study.2015
- Author(s)
  Morimoto K, Suzuki M, Ishifuji T, Yaegashi M, Asoh N, Hamashige N, Abe M, Aoshima M, Ariyoshi K; Adult Pneumonia Study Group-Japan (APSG-J).
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0122247-e0122247
- DOI
  10.1371/journal.pone.0122247
- NAID
  120006987098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460761
[Journal Article] Defective efferocytosis by alveolar macrophages in IPF patients.2012
- Author(s)
  Morimoto K, Janssen WJ, Terada M.
- Journal Title
  
  Respiratory Medicine
  
  Volume: 106 Issue: 12 Pages: 1800-1803
- DOI
  10.1016/j.rmed.2012.08.020
- NAID
  120006985828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591169
[Journal Article] Receptor for advanced glycation end products binds to phosphatidylse rine and assists in the clearance of apoptotic cells.2011
- Author(s)
  He M, Kubo H, Morimoto K, Fujino N, Suzuki T, Takahasi T, Yamada M, Yamaya M, Maekawa T, Yamamoto Y, Yamamoto H
- Journal Title
  
  EMBO Rep.
  
  Volume: 12 Pages: 358-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590900
[Journal Article] Receptor for advanced glycation end products binds to phosphatidylserine and assists in the clearance of apoptotic cells.2011
- Author(s)
  He M, Kubo H, Morimoto K, Fujino N, Suzuki T, Takahasi T, Yamada M, Yamaya M, Maekawa T, Yamamoto Y, Yamamoto H.
- Journal Title
  
  EMBO Rep. 12(4)
  
  Pages: 358-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590900
[Journal Article] Monocyte chemoattractant protein-1/CC chemokine ligand 2 enhances apoptotic cell removal by macrophages through Racl activation2010
- Author(s)
  Tanaka T, Terada M, Ariyoshi K, Morimoto K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 399 Pages: 677-682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590900
[Journal Article] Monocyte chemoattractant protein-1/CC chemokine ligand 2 enhances apoptotic cell removal by macrophages through Rac1 activation.2010
- Author(s)
  Tanaka T, Terada M, Ariyoshi K, Morimoto K.
- Journal Title
  
  Biochem Biophys Res Commun. 399
  
  Pages: 677-682
- NAID
  120006985830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590900
[Presentation] 小胞体ストレスはPERK経路を介してefferocytosisを抑制する2017
- Author(s)
  伊藤博之, 山下嘉郎, 泉田真衣, 高木理博, 田中健之, 森本浩之輔
- Organizer
  日本肺サーファクタント・界面医学会
- Data Source
  KAKENHI-PROJECT-16K09545
[Presentation] タバコ煙抽出液は小胞体ストレスによってRhoA依存性にefferocytosisを抑制する2016
- Author(s)
  森本浩之輔
- Organizer
  日本呼吸器学会学術総会
- Place of Presentation
  京都国際会館（京都府、京都市）
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-24591169
[Presentation] Cigarette smoke extract induced endoplasmic reticulum stress suppresses efferocytosis by macrophages through RhoA activation2015
- Author(s)
  森本浩之輔
- Organizer
  米国胸部疾患学会
- Place of Presentation
  米国コロラド州デンバー
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591169
[Presentation] 日本における成人肺炎の疫学2014
- Author(s)
  森本浩之輔、Adult pneumonia study group-Japan(研究グループの全員を代表する）
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  大阪(大阪国際会議場　大阪市北区中之島５丁目３－５１）
- Data Source
  KAKENHI-PROJECT-25460761
[Presentation] Production of Hepatocyte Growth Factor by Alveolar Macrophages that Have Engulfed Apoptotic Cells is Impaired in Streptozotocin-induced Diabetetic Mice.2011
- Author(s)
  Morimoto K, Kuroki R, Yamashita Y, Tanaka T, Takaki M, Ariyoshi K, Amano H
- Organizer
  American Thoracic Society International Conference
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-20590900
[Presentation] 肺の炎症巣でのアポトーシス細胞貪食除去(Efferocytosis)におけるMCP-1/CCR2の役割2009
- Author(s)
  田中健之、寺田真由美、森本浩之輔、有吉紅也
- Organizer
  日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20590900
[Presentation] 肺の炎症巣でのアポトーシス細胞貪食除去におけるMCP-1/CCL2の役割2009
- Author(s)
  田中健之、寺田真由美、森本浩之輔、有吉紅也
- Organizer
  第49回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20590900
[Presentation] MCP-1/CCL2 (Monocyte Chemoattractant Protein-1/CC Chemokine Ligand-2) enhance apoptotic cells removal(efferocytosis) through activation of Rac1.2009
- Author(s)
  田中健之, 森本浩之輔, 有吉紅也
- Organizer
  American Thoracic Society International Conference
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-20590900
[Presentation] MCP-1/CCL2(Monocyte Chemoattractant Protein-1/CC Chemokine Ligand-2)enhance apoptotic cells removal(efferocytosis)through activation of Racl.2009
- Author(s)
  田中健之、寺田真由美、森本浩之輔、有吉紅也
- Organizer
  American Thoracic Society International Conference.
- Place of Presentation
  米国サンディエゴ
- Data Source
  KAKENHI-PROJECT-20590900
[Presentation] びまん性肺疾患における気管支肺胞洗浄液中肺胞マクロファージのアポトーシス細胞貪食率.2008
- Author(s)
  森本浩之輔, 寺田真由美, 田中健之, 土橋佳子, 有吉紅也
- Organizer
  第48回日本呼吸器学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590900
[Presentation] COPDにおけるapoptotic cell clearanceの意義.2008
- Author(s)
  森本浩之輔
- Organizer
  第60回日本呼吸器学会日本結核病学会九州地方会春季大会
- Place of Presentation
  宮崎
- Year and Date
  2008-04-26
- Data Source
  KAKENHI-PROJECT-20590900

1. TANAKA Takeshi (30432967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. Isao Ito (40447975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. FURUMOTO Akitsugu (50380952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. DHOUBHADEL Bhim Gopal (80761113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUZUKI Motoi (60444874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 浅香勲 (10543639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MORIMOTO Konosuke 森本 浩之輔

Research Projects

Research Products

Co-Researchers

パンデミック後を見据えた急性呼吸器感染症サーベイランスの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高齢者肺炎における肺炎球菌保菌調査の構築と分析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of protective mechanism of acute lung injury via serotonin transporter/serotonin blockade

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Can endoplasmic reticulum stress on alveolar macrophages be a therapeutic target for lung fibrosis?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for pulmonary fibrosis using iPS cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Deveropement of nano-fludic technology based PCR for epidemiology of pneumococcus serotypes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The impact of ER stress on resolution of inflammation and tissue repair in lungPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Efferocytosis as a novel therapeutic target of emphysemaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impairment of tissue repair in pneumonia due to β-cell deficiency: role of endoplasmic reticulum stress in alveolar macrophages.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The burden and etiology of community-onset pneumonia in the aging Japanese population: a multicenter prospective study.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Defective efferocytosis by alveolar macrophages in IPF patients.2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Receptor for advanced glycation end products binds to phosphatidylse rine and assists in the clearance of apoptotic cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Receptor for advanced glycation end products binds to phosphatidylserine and assists in the clearance of apoptotic cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Monocyte chemoattractant protein-1/CC chemokine ligand 2 enhances apoptotic cell removal by macrophages through Racl activation2010

Author(s)

MORIMOTO Konosuke 森本浩之輔