KOBORI Masuko 小堀真珠子

Researcher Number	50353941
Other IDs
Affiliation (Current)	2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 国立健康・栄養研究所食品保健機能研究センター, センター長
Affiliation (based on the past Project Information) *help	2017: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門, ユニット長 2016: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門食品健康機能研究領域, ユニット長 2015: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門・食品健康機能研究領域, ユニット長 2014: 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・食品機能研究領域, 上席研究員 2013 – 2014: 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所食品機能研究領域, 上席研究員 2011 – 2012: 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・食品機能研究領域, 上席研究員 2009 – 2010: National Agricultural Research Organization, 食品総合研究所食品機能研究領域, ユニット長
Review Section/Research Field	Principal Investigator Eating habits, studies on eating habits / Eating habits
Keywords	Principal Investigator 内臓脂肪組織 / 免疫 / 肥満 / ケルセチン / β-クリプトキサンチン / 慢性炎症 / クルクミン / 内臓脂肪蓄積 / アレルギー / 皮膚炎 … More / NF-κB / Akt / チロシンキナーゼ / 喘息 / T細胞 / マスト細胞 / フラボノイド Less

Suppressive effects of dietary antioxidants on inflammation of visceral adipose tissues in diet-induced obese micePrincipal Investigator
- Principal Investigator
  
  KOBORI Masuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  National Agriculture and Food Research Organization
Improvement of immune system by food components in visceral adipose tissues of diet-induced obese micePrincipal Investigator
- Principal Investigator
  
  KOBORI Masuko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  National Agriculture and Food Research Organization
Suppressive effect of flavonoid on mast cell activation related to remodeling in asthmaPrincipal Investigator
- Principal Investigator
  
  KOBORI Masuko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  National Agriculture and Food Research Organization

All 2017 2016 2015 2014 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Quercetin suppresses immune cell accumulation and improves mitochondrial gene expression in adipose tissue of diet-induced obese mice.2016
- Author(s)
  Masuko Kobori, Yumiko Takahashi, Mutsumi Sakurai, Yukari Akimoto, Tojiro Tsushida, Hideaki Oike, Katsunori Ippoushi
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 60 Issue: 2 Pages: 300-312
- DOI
  10.1002/mnfr.201500595
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K00867
[Journal Article] Chronic high intake of quercetin reduces oxidative stress and induces expression of the antioxidant enzymes in the liver and visceral adipose tissues in mice.2015
- Author(s)
  Masuko Kobori, Yumiko Takahashi, Yukari Akimoto, Mutsumi Sakurai, Izumi Matsunaga, Haruno Nishimuro, Katsunari Ippoushi, Hideaki Oike, Mayumi Ohnishi-Kameyama
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 15 Pages: 551-560
- DOI
  10.1016/j.jff.2015.04.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24501024
[Journal Article] High glucose increases the expression of proinflammatory cytokines and secretion of TNFα and β-hexosaminidase in human mast cells2012
- Author(s)
  Nagai K, Fukushima T, Oike H, Kobori M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 687(1-3) Issue: 1-3 Pages: 39-45
- DOI
  10.1016/j.ejphar.2012.04.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501024
[Journal Article] The hydroxyflavone, fisetin, suppresses mast cell activation induced by interaction with activated T cell membranes2009
- Author(s)
  Kanji Nagai, Yumiko Takahashi, Ichiho Mikamim Tatsunobu Fukushima, Hideaki Oike and Masuko Kobori
- Journal Title
  
  British Journal of Pharmacology 2009
  
  Volume: 158(3) Issue: 3 Pages: 907-919
- DOI
  10.1111/j.1476-5381.2009.00365.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500814
[Presentation] Effect of the antioxidant curcumin on transcriptome and lipid profiles in visceral adipose tissues of diet-induced obese mice.2017
- Author(s)
  Masuko Kobori, Yumiko Takahashi, Hiroaki Takeda, Masatomo Takahashi, Yukari Akimoto, Mutsumi Sakurai, Hideaki Oike, Yoshihiro Izumi, Takeshi Bamba, Toshiyuki Kimura
- Organizer
  ISNFF2017 The International Conference and Exhibition on Nutraceutical & Functional Foods
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00867
[Presentation] クルクミンが食餌性肥満モデルマウスの精巣上体脂肪組織に及ぼす影響2017
- Author(s)
  小堀真珠子,高橋弓子,秋元由香里,桜井睦,大池秀明,木村俊之
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K00867
[Presentation] Curcumin alters gene expression and lipid profiles in visceral adipose tissue of diet-induced obese mice2017
- Author(s)
  Masuko Kobori, Yumiko Takahashi, Hiroaki Takeda, Masatomo Takahashi, Yukari Akimoto, Mutsumi Sakurai, Hideaki Oike, Yoshihiro Izumi, Takeshi Bamba, Toshiyuki Kimura
- Organizer
  46th Annual Meeting of Food and Agriculture Panel,US-Japan Cooperative Program in Natural Resources
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00867
[Presentation] ケルセチンの摂取は食餌性肥満モデルにおける精巣上体脂肪組織の炎症を抑制する2016
- Author(s)
  小堀真珠子、高橋弓子、桜井睦、秋元由香里、大池秀明、一法師克成
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K00867
[Presentation] Dietary Quercetin Suppresses inflammation of Visceral Adipose Tissue and Improves Metabolic Syndrome in Diet-induced Obese Mice.2016
- Author(s)
  Masuko Kobori
- Organizer
  7th Annual Conference American Council for Medicinally Active Plants.
- Place of Presentation
  リマ（ペルー）
- Year and Date
  2016-06-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00867
[Presentation] ffects of curcumin and quercetin on diet-induced obesity and metabolic syndrome in mice.2016
- Author(s)
  Masuko Kobori
- Organizer
  45th United States-Japan Cooperative Program in. Natural Resources (UJNR) Food and Agriculture Panel Meeting.
- Place of Presentation
  ホノルル（アメリカ）
- Year and Date
  2016-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00867
[Presentation] Quercetin suppresses the accumulation of immune cells in epididymal adipose tissues of diet-induced obese mice2015
- Author(s)
  Masuko Kobori
- Organizer
  International Conference on Food Factors (ICoFF2015)
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2015-11-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00867
[Presentation] ケルセチンが西洋型食で誘導される脂肪組織の免疫システム活性化に及ぼす影響2014
- Author(s)
  山内優輝、高橋弓子、秋元由香里、大池秀明一法師克成小堀真珠子
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学（神奈川県）
- Data Source
  KAKENHI-PROJECT-24501024
[Presentation] グルコースがマスト細胞の活性化に及ぼす影響2012
- Author(s)
  永井寛治, 小堀真珠子
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学(京都府)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-21500814
[Presentation] グルコースがマスト細胞の活性化に及ぼす影響2012
- Author(s)
  永井寛治、福島達伸、大池秀明、小堀真珠子
- Organizer
  日本農芸化学会2012年度大会要旨集
- Place of Presentation
  京都
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-21500814
[Presentation] 活性化T細胞刺激によるマスト細胞活性化に対するフラボノイドの抑制効果2011
- Author(s)
  永井寛治、福島達伸、大池秀明、小堀真珠子
- Organizer
  日本農芸化学会2011年度大会
- Place of Presentation
  京都
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21500814
[Presentation] 活性化T細胞刺激によるマスト細胞活性化に対するフラボノイドの抑制効果2011
- Author(s)
  永井寛治、福島達伸、大池秀明、小堀真珠子
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学(京都府)
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21500814
[Presentation] グルコースのマスト細胞活性化作用2010
- Author(s)
  永井寛治、福島達伸、大池秀明、小堀真珠子
- Organizer
  日本食品科学工学会
- Place of Presentation
  東京農大学
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21500814
[Presentation] グルコースのマスト細胞活性化作用2010
- Author(s)
  永井寛治、福島達伸、大池秀明、小堀真珠子
- Organizer
  日本食品科学工学会
- Place of Presentation
  東京農業大学(東京都)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21500814
[Presentation] 活性化T細胞接着刺激によるマスト細胞の活性化機構2009
- Author(s)
  永井寛治、小堀真珠子
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21500814

1. NAGAI Kanji

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

KOBORI Masuko 小堀 真珠子

Research Projects

Research Products

Co-Researchers

Suppressive effects of dietary antioxidants on inflammation of visceral adipose tissues in diet-induced obese micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Improvement of immune system by food components in visceral adipose tissues of diet-induced obese micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Suppressive effect of flavonoid on mast cell activation related to remodeling in asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Quercetin suppresses immune cell accumulation and improves mitochondrial gene expression in adipose tissue of diet-induced obese mice.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic high intake of quercetin reduces oxidative stress and induces expression of the antioxidant enzymes in the liver and visceral adipose tissues in mice.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High glucose increases the expression of proinflammatory cytokines and secretion of TNFα and β-hexosaminidase in human mast cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The hydroxyflavone, fisetin, suppresses mast cell activation induced by interaction with activated T cell membranes2009

Author(s)

Journal Title

DOI

Data Source

[Presentation] Effect of the antioxidant curcumin on transcriptome and lipid profiles in visceral adipose tissues of diet-induced obese mice.2017

Author(s)

Organizer

Data Source

[Presentation] クルクミンが食餌性肥満モデルマウスの精巣上体脂肪組織に及ぼす影響2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Curcumin alters gene expression and lipid profiles in visceral adipose tissue of diet-induced obese mice2017

Author(s)

Organizer

Data Source

[Presentation] ケルセチンの摂取は食餌性肥満モデルにおける精巣上体脂肪組織の炎症を抑制する2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Dietary Quercetin Suppresses inflammation of Visceral Adipose Tissue and Improves Metabolic Syndrome in Diet-induced Obese Mice.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ffects of curcumin and quercetin on diet-induced obesity and metabolic syndrome in mice.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Quercetin suppresses the accumulation of immune cells in epididymal adipose tissues of diet-induced obese mice2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KOBORI Masuko 小堀真珠子