Sakamoto Kimitoshi 坂元君年

… Alternative Names

坂元君年サカモトキミトシ

SAKAMOTO Kimitoshi 坂元君年

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Researcher Number	50361465
Other IDs
Affiliation (Current)	2025: 弘前大学, 農学生命科学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 弘前大学, 農学生命科学部, 准教授 2011 – 2017: 弘前大学, 農学生命科学部, 准教授 2008: 東大, 医学(系)研究科(研究院), 助教 2007: The University of Tokyo, 大学院・医学系研究科, 助教 2004 – 2005: 東京大学, 大学院・医学系研究科, 助手
Review Section/Research Field	Principal Investigator Parasitology (including Sanitary zoology) / Basic Section 38040:Bioorganic chemistry-related / Parasitology (including sanitary zoology) Except Principal Investigator Medium-sized Section 38:Agricultural chemistry and related fields / Basic Section 44040:Morphology and anatomical structure-related / Morphology/Structure
Keywords	Principal Investigator ミトコンドリア呼吸鎖 / 蠕虫 / キノール酸化酵素 / アスコフラノン / シアン耐性末端酸化酵素 / トリパノソーマ / 水酸化-脱炭酸反応 / 水酸化ー脱炭酸酵素 / 脱炭酸酵素 / 水酸化酵素 … More / ユビキノン生合成 / ロドキノン / コハク酸脱水素酵素 / ミトコンドリア … More Except Principal Investigator 生殖様式転換 / プラナリア / 電子伝達系 / 余剰還元力 / 物質生産 / 低酸素 / 嫌気 / ロドキノン / 低酸化還元電位型キノン / 嫌気的呼吸鎖 / バイオリファイナリー / 脂質性リガンド / 有性化 / 脂溶性リガンド / カンテツ / 核内受容体 / 有性化因子 / 生殖細胞 / 生殖様式 Less

水酸化-脱炭酸反応から読み解くユビキノン生合成Principal Investigator
- Principal Investigator
  
  坂元君年
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Hirosaki University
Development of anaerobic biorefinery utilize anaerobic respiratory chain
- Principal Investigator
  
  Nakazawa Masami
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Identification and analysis of lipophilic ligands for the nuclear receptor essential for planarian sexualization
- Principal Investigator
  
  Kobayashi Kazuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  Hirosaki University
Identification of sex-inducing substances that can trigger the switching from asexual to sexual reproduction in planarians.
- Principal Investigator
  
  Kazuya Kobayashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphology/Structure
- Research Institution
  Hirosaki University
Reaction mechanism analysis and inhibitor screening of helminthic fumarate quinone reductasePrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Kimitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Hirosaki University
Development of the expression system of helminthic mitochondrial quinol-fumarate reductase in bacteria.Principal Investigator
- Principal Investigator
  
  SAKAMOTO Kimitoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Hirosaki University
アフリカトリパノソーマシアン耐性キノール酸化酵素の分子機構Principal Investigator
- Principal Investigator
  
  坂元君年
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  The University of Tokyo
アフリカトリパノソーマミトコンドリア末端酸化酵素キノール酸化反応の分子機構Principal Investigator
- Principal Investigator
  
  坂元君年
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  The University of Tokyo

All 2023 2021 2020 2017 2016 2015 2014 2013 2012 2011 2010 2006 2005 Other

All Journal Article Presentation

[Journal Article] UbiN, a novel Rhodobacter capsulatus decarboxylative hydroxylase involved in aerobic ubiquinone biosynthesis2023
- Author(s)
  Nagatani Haruka、Mae Yoshiyuki、Konishi Miharu、Matsuzaki Motomichi、Kita Kiyoshi、Daldal Fevzi、Sakamoto Kimitoshi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 13 Issue: 11 Pages: 2081-2093
- DOI
  10.1002/2211-5463.13707
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05048
[Journal Article] Identification of novel yolk ferritins unique to planarians: planarians supply aluminum rather than iron to vitellaria in egg capsules2021
- Author(s)
  Kawase Osamu、Iwaya Hisashi、Asano Yoshiya、Inoue Hiromoto、Kudo Seiya、Sasahira Motoki、Azuma Nobuyuki、Kondoh Daisuke、Ichikawa-Seki Madoka、Xuan Xuenan、Sakamoto Kimitoshi、Okamoto Hikaru、Nakadate Hinaki、Inoue Wataru、Saito Ikuma、Narita Miyu、Sekii Kiyono、Kobayashi Kazuya
- Journal Title
  
  Cell and Tissue Research
  
  Volume: 386 Issue: 2 Pages: 391-413
- DOI
  10.1007/s00441-021-03506-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05236, KAKENHI-PROJECT-19H03256, KAKENHI-PROJECT-21K05954, KAKENHI-PROJECT-19K16175
[Journal Article] The Open Form Inducer Approach for Structure-Based Drug Design2016
- Author(s)
  D. K. Inaoka, M. Iida, T. Tabuchi, T. Honma, N. Lee, S. Hashimoto, S. Matsuoka, T. Kuranaga, K. Sato, T. Shiba, K. Sakamoto, E. O. Balogun, S. Suzuki, T. Nara, J. R. Rocha, C. A. Montanari, A. Tanaka, M. Inoue, K. Kita, S. Harada
- Journal Title
  
  PLoS ONE
  
  Volume: 11 Issue: 11 Pages: e0167078-e0167078
- DOI
  10.1371/journal.pone.0167078
- NAID
  120006987593
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01130, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15J12403, KAKENHI-PROJECT-26304041, KAKENHI-PROJECT-26460504, KAKENHI-PROJECT-16K15268
[Journal Article] Knockdown of the coenzyme Q synthesis gene Smed-dlp1 affects planarian regeneration and tissue homeostasis2015
- Author(s)
  Shiobara Y, Harada C, Shiota T, Sakamoto K, Kita K, Tanaka S, Tabata K, Sekie K, Yamamoto Y, Sugiyama T
- Journal Title
  
  Redox Biol
  
  Volume: 6 Pages: 599-606
- DOI
  10.1016/j.redox.2015.10.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26350915, KAKENHI-PROJECT-26460504
[Journal Article] Enhancement of protocatechuate decarboxylase activity for the effective production of muconate from lignin-related aromatic compounds.2014
- Author(s)
  Sonoki T., Morooka M., Sakamoto K., Otsuka Y., Nakamura M, Jellison J, Goodell B.
- Journal Title
  
  Journal of Biotechnology
  
  Volume: 192 Pages: 71-77
- DOI
  10.1016/j.jbiotec.2014.10.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460504, KAKENHI-PROJECT-26850041
[Journal Article] Pharmacophore identification of ascofuranone, potent inhibitor of cyanide-insensitive alternative oxidase of Trypanosoma brucei2013
- Author(s)
  Saimoto H, Kido Y, Haga Y, Sakamoto K, Kita K
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 153 Pages: 267-273
- Data Source
  KAKENHI-PROJECT-23590484
[Journal Article] Structure of the trypanosome cyanide-insensitive alternative oxidase2013
- Author(s)
  Shiba T, Kido Y, Sakamoto K, Inaoka DK, Tsuge C, Tatsumi R, Takahashi G, Balogun EO, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Saimoto H, Moore AL, Harada S, Kita K
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 110 Pages: 4580-4585
- Data Source
  KAKENHI-PROJECT-23590484
[Journal Article] Cloning and characterization of hypoxia-inducible factor-1 subunits from Ascaris suum - a parasitic nematode highly adapted to changes of oxygen conditions during its life cycle2013
- Author(s)
  Goto, M., Amino, H., Nakajima, M., Tsuji, N., Sakamoto, K., Kita, K.
- Journal Title
  
  Gene
  
  Volume: 516 Issue: 1 Pages: 39-47
- DOI
  10.1016/j.gene.2012.12.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590484
[Journal Article] Age-related changes in the activities of respiratory chain complexes and mitochondrial morphology in Drosophila2012
- Author(s)
  Oda Y, Yui R, Sakamoto K, Kita K, Matsuura ET
- Journal Title
  
  Mitochondrion
  
  Volume: 12 Pages: 345-351
- Data Source
  KAKENHI-PROJECT-23590484
[Journal Article] Crystal structure of mitochondrial quinol-fumarate reductase from the parasitic nematode Ascaris suum2012
- Author(s)
  Shimizu H, Osanai A, Sakamoto K, Inaoka D K, Shiba T, Harada S, Kita K
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 151 Pages: 589-592
- NAID
  10031166100
- Data Source
  KAKENHI-PROJECT-23590484
[Journal Article] Age-related changes in the activities of respiratory chain complexes and mitochondrial morphology in Drosophila.2011
- Author(s)
  Oda, Y., Yui, R., Sakamoto, K., Kita, K., Matsuura, E.T.
- Journal Title
  
  Mitochondrion
  
  Volume: 12 Issue: 2 Pages: 345-351
- DOI
  10.1016/j.mito.2012.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590484
[Journal Article] Ukulactones A and B, new NADH-fumarate reductase inhibitors produced by Penicillium sp. FKI-33892011
- Author(s)
  Mori M, Morimoto H, Kim YP, Ui H, Nonaka K, Masuma R, Sakamoto K, Kita K, Tomoda H, Shiomi K, Omura S
- Journal Title
  
  Tetrahedron
  
  Volume: 67 Pages: 6582-6586
- Data Source
  KAKENHI-PROJECT-23590484
[Journal Article] Uklactones A and B, new NADH-fumarate reductase inhibitors produced by Penicillium sp.FKI-33892011
- Author(s)
  M.Mori, H.Morimoto, Y.-P.Kim, H.Ui, K.Nonaka, R.Masuma, K.Sakamoto, K.Kita, H.Tomoda, K.Shiomi, S.Omura
- Journal Title
  
  Tetrahedron
  
  Volume: 67 Issue: 35 Pages: 6582-6586
- DOI
  10.1016/j.tet.2011.05.090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580129, KAKENHI-PROJECT-23590484
[Journal Article] Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies2010
- Author(s)
  Nakamura, K., Fujioka, S., Fukumoto, S., Inoue, N., Sakamoto, K., Hirata, H., Kido, Y., Yabu, Y., Suzuki, T., Watanabe, Y., Saimoto, H., Akiyama, H. and Kita, K.
- Journal Title
  
  Parasitology International
  
  Volume: 59 (4) Issue: 4 Pages: 560-564
- DOI
  10.1016/j.parint.2010.07.006
- NAID
  10029826326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380186, KAKENHI-PROJECT-23590484
[Journal Article] Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus2006
- Author(s)
  Nishida S, Kurokawa K, Matsuo M, Sakamoto K, Ueno K, Kita K, Sekimizu K
- Journal Title
  
  The Journal of Biological Chemistry 281
  
  Pages: 1714-1724
- Data Source
  KAKENHI-PROJECT-16790244
[Journal Article] Mass spectrometric analysis of the ubiquinol-binding site in cytochrome bd from Escherichia coli2006
- Author(s)
  Matsumoto Y, Murai M, Fujita D, Sakamoto K, Miyoshi H, Yoshida M, Mogi T
- Journal Title
  
  The Journal of Biological Chemistry 281
  
  Pages: 1905-1912
- Data Source
  KAKENHI-PROJECT-16790244
[Journal Article] Mutational analysis of the Trypanosoma vivax alternative oxidase : The E(X)_6Y motif is conserved in both mitochondrial alternative oxidase and plastid terminal oxidase and is indispensable for enzyme activity2005
- Author(s)
  Nakamura K, Sakamoto K, Kido Y, Fujimoto Y, Suzuki T, Suzuki M, Yabu Y, Ohta N, Tsuda A, Onuma M, Kita K.
- Journal Title
  
  Biochemical and Biophysical Research Communications 334
  
  Pages: 593-600
- Data Source
  KAKENHI-PROJECT-16790244
[Journal Article] Alternative Oxidase (AOX) Genes of African Trypanosomes : Phylogeny and Evolution of AOX and Plastid Terminal Oxidase Families2005
- Author(s)
  Suzuki T, Hashimoto T, Yabu Y, Majiwa PA, Ohshima S, Suzuki M, Lu S, Hato M, Kido Y, Sakamoto K, Nakamura K, Kita K, Ohta N
- Journal Title
  
  The Journal of Eukaryotic Microbiology 52
  
  Pages: 374-381
- Data Source
  KAKENHI-PROJECT-16790244
[Presentation] ユビキノン生合成水酸化酵素が脱炭酸能を有する可能性2023
- Author(s)
  小西美晴、永谷悠、坂元君年
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K05048
[Presentation] 新たなユビキノン生合成水酸化脱炭酸酵素の同定2023
- Author(s)
  小西美晴、永谷悠、坂元君年
- Organizer
  日本コエンザイムQ協会第20回研究会
- Data Source
  KAKENHI-PROJECT-23K05048
[Presentation] 電子伝達体キノンの構成改変による物質生産転換法の開発2021
- Author(s)
  長谷川雅樹、中澤昌美、坂元君年、柏山祐一郎、上田光宏、阪本龍司
- Organizer
  第31回イソプレノイド研究会
- Data Source
  KAKENHI-PROJECT-20K21287
[Presentation] ロドキノンを介する嫌気的呼吸鎖と共役した長鎖脂肪酸合成系の解明2020
- Author(s)
  中澤昌美、髙橋夢月、乾　博、坂元君年、上田光宏、阪本龍司
- Organizer
  第30回イソプレノイド研究会
- Data Source
  KAKENHI-PROJECT-20K21287
[Presentation] メタボローム解析を用いたプラナリア有性化因子の同定2017
- Author(s)
  宮下奏一郎・石川正樹・虻川真里奈・関井清乃・坂元君年・前澤孝信・小林一也
- Organizer
  日本動物学会第88回富山大会
- Data Source
  KAKENHI-PROJECT-15K07121
[Presentation] Rhodobacter capsulatus由来bdキノール酸化酵素の解析2016
- Author(s)
  坂元君年, 佐々木智子, Fevzi Daldal
- Organizer
  日本生化学会東北支部第82回例会
- Place of Presentation
  弘前大学
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26460504
[Presentation] ユビキノンおよびロドキノンの機能研究材料としてのプラナリア2016
- Author(s)
  鎌田紗綾, 坂元君年
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  東北大学
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460504
[Presentation] アルファプロテオバクテリア綱の細菌が持つコハク酸脱水素酵素の鉄硫黄クラスター近傍アミノ酸変異による活性制御の解析2016
- Author(s)
  前田晴香、Fevzi Daldal、坂元君年
- Organizer
  日本農芸化学会2016年大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460504
[Presentation] Rhodobacter capsulatusとRhodospirillum rubrum間でのキメラ型コハク酸‐ユビキノン還元酵素の作製2013
- Author(s)
  福士実咲・柴谷恵太・Hendri Aldrat・北潔・Fevzi Daldal・坂元君年
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜・横浜
- Data Source
  KAKENHI-PROJECT-23590484
[Presentation] Rhodobacter capsulatusとRhodospirillum rubrum間でのキメラ型コハク酸‐ユビキノン還元酵素の作製2013
- Author(s)
  福士実咲、柴谷恵太、Hendri Aldrat、北潔、Fevzi Daldal、坂元君年
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590484
[Presentation] 紅色光合成細菌Rhodobacter capsulatusを用いたコハク酸脱水素酵素複合体の異種生物間発現2012
- Author(s)
  坂元君年・Hendri Aldrat・北潔
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学
- Data Source
  KAKENHI-PROJECT-23590484
[Presentation] コハク酸脱水素酵素複合体の異種生物間発現系の開発2011
- Author(s)
  坂元君年・Hendri Aldrat・北潔
- Organizer
  日本農芸化学会東北支部第146回大会
- Place of Presentation
  山形大学
- Data Source
  KAKENHI-PROJECT-23590484
[Presentation] コハク酸脱水素酵素複合体の異種生物間発現系の開発
- Author(s)
  坂元　君年、Hendri Aldrat、北　潔
- Organizer
  日本農芸化学会東北支部
- Place of Presentation
  山形大学農学部
- Data Source
  KAKENHI-PROJECT-23590484
[Presentation] 淡水性プラナリアからのミトコンドリア単離
- Author(s)
  室川聡大、櫻田拓也、坂元君年
- Organizer
  第87回生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460504
[Presentation] 紅色光合成細菌Rhodobacter capsulatusを用いたコハク酸脱水素酵素複合体の異種生物間発現
- Author(s)
  坂元　君年、Aldrat Hendri、北　潔
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学
- Data Source
  KAKENHI-PROJECT-23590484

1. Kazuya Kobayashi (50360110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. Nakazawa Masami (90343417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 関まどか (20700488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 柏山祐一郎 (00611782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 藤原崇之 (10595151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KAZURO Shiomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. MASUMA Rokuro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 井上昇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 渡辺純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 山本順寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 井上将行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakamoto Kimitoshi 坂元 君年

坂元 君年 サカモト キミトシ

SAKAMOTO Kimitoshi 坂元 君年

Research Projects

Research Products

Co-Researchers

水酸化-脱炭酸反応から読み解くユビキノン生合成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of anaerobic biorefinery utilize anaerobic respiratory chain

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and analysis of lipophilic ligands for the nuclear receptor essential for planarian sexualization

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of sex-inducing substances that can trigger the switching from asexual to sexual reproduction in planarians.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Reaction mechanism analysis and inhibitor screening of helminthic fumarate quinone reductasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the expression system of helminthic mitochondrial quinol-fumarate reductase in bacteria.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アフリカトリパノソーマシアン耐性キノール酸化酵素の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アフリカトリパノソーマミトコンドリア末端酸化酵素キノール酸化反応の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] UbiN, a novel Rhodobacter capsulatus decarboxylative hydroxylase involved in aerobic ubiquinone biosynthesis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of novel yolk ferritins unique to planarians: planarians supply aluminum rather than iron to vitellaria in egg capsules2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Open Form Inducer Approach for Structure-Based Drug Design2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Knockdown of the coenzyme Q synthesis gene Smed-dlp1 affects planarian regeneration and tissue homeostasis2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhancement of protocatechuate decarboxylase activity for the effective production of muconate from lignin-related aromatic compounds.2014

Author(s)

Journal Title

DOI

Data Source

Sakamoto Kimitoshi 坂元君年

坂元君年サカモトキミトシ

SAKAMOTO Kimitoshi 坂元君年