NAKAGAWA Takeya 中川武弥

… Alternative Names

Researcher Number	50363502
Other IDs
External Links
Affiliation (Current)	2019: 長崎大学, 医歯薬学総合研究科(医学系), 助教
Affiliation (based on the past Project Information) *help	2017 – 2019: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2014: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2012 – 2013: 長崎大学, 医歯(薬)学総合研究科, 助教 2007 – 2012: 長崎大学, 大学院・医歯薬学総合研究科, 助教 2010 – 2011: 長崎大学, 大学院・医歯(薬)学総合研究科, 助教 2005 – 2006: 長崎大学, 大学院医歯薬学総合研究科, 助手 2004 – 2005: Nagasaki University, Graduate School of Biomedical Sciences, Research Associate, 大学院・医歯薬学総合研究科, 助手
Review Section/Research Field	Principal Investigator Molecular biology Except Principal Investigator General medical chemistry / Biological Sciences
Keywords	Principal Investigator 遺伝子 / 転写調節 / piRNA / ヒストン修飾 / 脱リン酸化 / ヒストン / 試験管内遺伝子転写 / genome / 遺伝子転写 / 転写 … More Except Principal Investigator 遺伝子転写 / クロマチン / ヒストン / ユビキチン化 / エピジェネティクス / ヌクレオソーム / リン酸化 / アセチル化 / 翻訳後修飾 / 転写開始 / 脱ユビキチン化 / USP21 / nucleosome / DNA高次構浩 / transcription / histone / chromatin / 再構築 / 肝再生 / acetylation / phosphorylation / 高次構造 / クロストーク / H2A / SOX2 / マイクロアレイ / TBP / DNA高次構造 / リモデリング / 部分肝切除 Less

Chromatin remodeling and Induction of pluripotency via Sox2/TBP complexOngoing
- Principal Investigator
  
  伊藤敬
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki University
ゲノムDNAを鋳型とする試験管内遺伝子転写系を用いた新奇SOX2複合体の機能解析Principal InvestigatorOngoing
- Principal Investigator
  
  中川武弥
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Nagasaki University
Analysis of piRNA biosynthesis mechanism and identification of its target genePrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Takeya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Nagasaki University
Analysis of gene transcription start regulatory mechanism by crosstalk between histone modificationsPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Takeya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Nagasaki University
Post-translational histnoe modification and transcriptional regulation.
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki University
Mechanisms of transcriptional regulation by histone H2A specific deubiquitylase
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki University
Post-translational histnoe modification and chromatin strucure
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
Phosphorylation and ubiquitylation of H2A regulate chromatin structure and function
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki University
Analysis of effect for DNA structure by phosphorylation of histone proteinPrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Takeya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Nagasaki University
Core histone modifications change the higher order of DNA structurec resulting in its biological output
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki University

All 2018 2013 2010 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] 新ラボマニュアル遺伝子工学2003
- Author(s)
  分担執筆池原強, 中川武弥, 伊藤敬
- Total Pages
  291
- Publisher
  丸善株式会社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] MicroRNA-3662 expression correlates with antiviral drug resistance in adult T-cell leukemia/lymphoma cells.2018
- Author(s)
  Yasui K, Izumida M, Nakagawa T, Kubo Y, Hayashi H, Ito T, Ikeda H, Matsuyama T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中
- DOI
  10.1016/j.bbrc.2018.04.159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15319, KAKENHI-PROJECT-17H04044
[Journal Article] The USP21 Short Variant (USP21SV) Lacking NES, Located Mostly in the Nucleus In Vivo, Activates Transcription by Deubiquitylating ubH2A In Vitro2013
- Author(s)
  Hiroshi Okuda, Hideki Ohdan, Manabu Nakayama, Haruhiko Koseki, Takeya Nakagawa, Takashi Ito
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25840010
[Journal Article] Transcriptional activation of polycomb-repressed genes by ZRF12010
- Author(s)
  Richly H, Rocha-Viegas L, Ribeiro JD, Demajo S, Gundem G, Lopez-Bigas N, Nakagawa T, Rospert S, Ito T, Di Croce L.
- Journal Title
  
  Nature.
  
  Volume: 468 Pages: 1124-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570173
[Journal Article] Transcriptional activation of polycomb-repressed genes by ZRF12010
- Author(s)
  Richly H, Rocha-Viegas L, Ribeiro JD, Demajo S, Gundem G, Lopez-Bigas N, Nakagawa T, Rospert S, Ito T, Di Croce L
- Journal Title
  
  Nature
  
  Volume: 468 Pages: 1124-1128
- Data Source
  KAKENHI-PROJECT-21390085
[Journal Article] Transcriptional activation of polycomb-repressed genes by ZRF1.2010
- Author(s)
  Richly H, Rocha-Viegas L, Ribeiro JD, Demajo S, Gundem G, Lopez-Bigas N, Nakagawa T, Rospert S, Ito T, Di Croce L.
- Journal Title
  
  Nature
  
  Volume: 468 Pages: 1124-1128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390085
[Journal Article] Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di-and trimethylation.2008
- Author(s)
  Nakagawa, T., Kajitani, T., Togo, S., Masuko, N., Ohdan, H., Hishlkawa, Y., Koji, T., Matsuyama, T., Ikura, T., Murainatsu, M., and Ito, T.
- Journal Title
  
  Genes Dev 22
  
  Pages: 37-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390077
[Journal Article] Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation.2008
- Author(s)
  Nakagawa, T., Kajitani, T., Togo, S., Masuko, N., Ohdan, H., Hishikawa, Y., Koji, T., Matsuyama, T., Ikura, T., Muramatsu, M., Ito, T.
- Journal Title
  
  Genes Dev 22(1)
  
  Pages: 37-49
- Data Source
  KAKENHI-PROJECT-17054032
[Journal Article] Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di-and trimethylation.2008
- Author(s)
  Nakagawa, T., Kajitani, T., Togo, S., Masuko, N., Ohdan, H., Hishikawa, Y., Koji, T., Matsuyama, T., Ikura, T., Muramatsu, M., and Ito, T.
- Journal Title
  
  Genes Dev 22
  
  Pages: 37-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054032
[Journal Article] クロマチン再構築因子2006
- Author(s)
  難波泰明, 梶谷卓也, 中川武弥, 伊藤敬
- Journal Title
  
  蛋白質核酸酵素 51
  
  Pages: 2076-2082
- Data Source
  KAKENHI-PROJECT-17054032
[Journal Article] クロマチン再構築因子2006
- Author(s)
  難波泰明, 梶谷卓也, 中川武弥, 伊藤敬
- Journal Title
  
  蛋白質核酸酵素 51
  
  Pages: 2076-2082
- Data Source
  KAKENHI-PROJECT-17390083
[Journal Article] クロマチンと病態2005
- Author(s)
  中川武弥, 田頭英樹, 沖昌也, 伊藤敬
- Journal Title
  
  Molecular Medicine 42
  
  Pages: 966-972
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390083
[Journal Article] クロマチンと病態2005
- Author(s)
  中川武弥, 田頭英樹, 沖昌也, 伊藤敬
- Journal Title
  
  Molecular Medicine 42
  
  Pages: 966-972
- Data Source
  KAKENHI-PROJECT-17390083
[Journal Article] クロマチンと病態2005
- Author(s)
  中川武弥, 田頭英樹, 沖昌也, 伊藤敬
- Journal Title
  
  Molecular Medicine 42
  
  Pages: 966-972
- Data Source
  KAKENHI-PROJECT-17054032
[Journal Article] クロマチンと病態2005
- Author(s)
  中川武弥, 田頭英樹, 沖昌也, 伊藤敬
- Journal Title
  
  Molecular Medicine 42
  
  Pages: 966-972
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390083
[Journal Article] 2008. Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation2005
- Author(s)
  Nakagawa, T., Kajitani, T., Togo, S., Masuko, N., Ohdan, H., Hishikawa, Y., Koji, T., Matsuyama, T., Ikura, T., Muramatsu, M., and Ito, T
- Journal Title
  
  Genes Dev Dev22(1)
  
  Pages: 37-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390077
[Journal Article] Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo.2004
- Author(s)
  Aihara, H., Nakagawa, T., Yasui, K., Ohta, T., Hirose, S., Dhomae, N., Takio, K., Kaneko, M., Takeshima, Y., Muramatsu, M., Ito, T.
- Journal Title
  
  Genes Dev 18
  
  Pages: 877-888
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] Isoflavones stimulate estrogen receptor-mediated core histone acetylation.2004
- Author(s)
  Hong, T., Nakagawa, T et al.
- Journal Title
  
  Biochem Biophys Res Commun 317
  
  Pages: 259-264
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] Isoflavones stimulate estrogen receptor-mediated core histone acetylation.2004
- Author(s)
  Hong, T., Nakagawa, T., Pan, W., Kim, M.Y., Kraus, W.L, Ikehara, T., Yasui, K., Aihara, H., Takebe, M., Muramatsu, M., Ito, T.
- Journal Title
  
  Biochem Biophys Res Commun 317
  
  Pages: 259-264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] Isfolavones stimulate estrogen receptor-mediated core histone acetylation2004
- Author(s)
  Hong, T., Nakagawa, T., Pan, W., Kim, M.Y., Kraus, W.L., Ikehara, T., Yasui, K., Aihara, H., Takebe, M., Muramatsu, M., Ito, T.
- Journal Title
  
  Biochem Biophys Res Commun 317
  
  Pages: 259-264
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo.2004
- Author(s)
  Aihara, H., Nakagawa, T., Yasui, K., Ohta, T., Hirose, S., Dhomae, N., Takio, K., Kaneko, M., Takeshima, Y., Muramatsu, M., Ito, T
- Journal Title
  
  Genes Dev 18
  
  Pages: 877-888
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo.2004
- Author(s)
  Aihara, H., Nakagawa, T.et al.
- Journal Title
  
  Genes Dev 18
  
  Pages: 877-888
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] Signal transduction and chromatin2003
- Author(s)
  Nakagawa, T., Ito, T.
- Journal Title
  
  Tanpakushitu Kakusan Koso 48
  
  Pages: 2234-2240
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.2003
- Author(s)
  Kitagawa, H., Fujiki, R., Yoshimura, K., Mezaki, Y., Uematsu, Y., Matsui, D., Ogawa, S., Unno, K., Okubo, M., Tokita, A., Nakagawa, T., Ito, T.et al.
- Journal Title
  
  Cell 113
  
  Pages: 905-917
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] シグナル伝達とクロマチン制御2003
- Author(s)
  中川武弥, 伊藤敬
- Journal Title
  
  蛋白質核酸酵素 48
  
  Pages: 2234-2240
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Journal Article] The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.2003
- Author(s)
  Kitagawa, H., Fujiki, R., Yoshimura, K., Mezaki, Y., Uematsu, Y., Matsui, D., Ogawa, S., Unno, K., Okubo, M., Tokita, A., Nakagawa, T., Ito, T., Ishimi, Y., Nagasawa, H., Matsumoto, T., Yanagisawa, J., Kato, S.
- Journal Title
  
  Cell 113
  
  Pages: 905-917
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390098
[Presentation] Deubiquitylation of hisotne H2A activates transcriptiona initiation via trans-histone crosstalk with H3K4 di-and tri-methylation.2008
- Author(s)
  Nakagawa, T., Takuya Kajitani, Shinji Togo, Norio Masuko, Yoshitaka Hishikawa, Koji Takehiko, Toshifumi Matsuyama, Hideki, Ohdan, Tsuyoshi Ikura, Masami Muramatsu and Takashi Ito
- Organizer
  Keystone Symposia
- Place of Presentation
  Keystone
- Data Source
  KAKENHI-PROJECT-19390077
[Presentation] USP activates transcriptional initiation by isopeptide bond hydrolyzation of ubiquitylated H2A and trans-histone crosstalk2007
- Author(s)
  Nakagawa, T., Takuya Kajitani, Shinji Togo, Norio Masuko, Yoshitaka Hishikawa, Koji Takehiko, Toshifumi Matsuyama, Hideki, Ohdan, Tsuyoshi Ikura, Masami Muramatsu and Takashi Ito
- Organizer
  Keystone Symposia
- Place of Presentation
  Colorado
- Data Source
  KAKENHI-PROJECT-17054032
[Presentation] Keystone Symposia 2008 Regulatory Mechanismas in Eukaryotic transcription(Poster Session 2)
- Author(s)
  Takeya Nakagawa, Takuya Kajitani, Shinji Togo, Norio Masuko, Hideki, Ohdan, Yoshitaka Hishikawa, Koji Takehiko, Toshifumi Matsuyama, Tsuyoshi Ikura, Masami Muramatsu and Takashi Ito,
- Organizer
  Deubiquitylation of hisotne H2A activates transcriptiona initiation via trans-histone crosstalk with H3K4 di- and tri-methylation.Kevin Struhl, and John T. Lis
- Place of Presentation
  Keystone Ressort Keystone, Colorado
- Data Source
  KAKENHI-PROJECT-19390077
[Presentation] ATP-Dependent Stimulator of Nucleosomal Histone Acetylation (ASNA) modifies H2A during Transcriptional Activation
- Author(s)
  Masamichi Doiguchi, Takeya Nakagawa, Hitoshi Ueda, Masami Muramatsu, and Takashi Ito
- Place of Presentation
  Department of Biochemistry, Nagasaki University of Medicine, Nagasaki, Japan1. The Graduate School of Natural Science and Technology and Department of Biology, Faculty of Science, Okayama University, Tsushima-naka, Okayama, Japan2. Saitama Medical School
- Data Source
  KAKENHI-PROJECT-19390077

1. ITO Takashi (90306275)

# of Collaborated Projects: 7 results

# of Collaborated Products: 27 results
2. YASUI Kiyoshi (50372777)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. NANABA Yasuaki (90444869)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MIZUSAKI Hirofumi (40467957)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 沖昌也 (60420626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 今村優子 (50610937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. IKEHARA Tsuyoshi (90359951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 米田光宏 (80508367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 林日出喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAGAWA Takeya 中川 武弥

中川 武弥 ナカガワ タケヤ

Research Projects

Research Products

Co-Researchers

Chromatin remodeling and Induction of pluripotency via Sox2/TBP complexOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ゲノムDNAを鋳型とする試験管内遺伝子転写系を用いた新奇SOX2複合体の機能解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of piRNA biosynthesis mechanism and identification of its target genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of gene transcription start regulatory mechanism by crosstalk between histone modificationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Post-translational histnoe modification and transcriptional regulation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of transcriptional regulation by histone H2A specific deubiquitylase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Post-translational histnoe modification and chromatin strucure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Phosphorylation and ubiquitylation of H2A regulate chromatin structure and function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of effect for DNA structure by phosphorylation of histone proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Core histone modifications change the higher order of DNA structurec resulting in its biological output

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 新ラボマニュアル遺伝子工学2003

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] MicroRNA-3662 expression correlates with antiviral drug resistance in adult T-cell leukemia/lymphoma cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The USP21 Short Variant (USP21SV) Lacking NES, Located Mostly in the Nucleus In Vivo, Activates Transcription by Deubiquitylating ubH2A In Vitro2013

Author(s)

Journal Title

Data Source

NAKAGAWA Takeya 中川武弥

中川武弥ナカガワタケヤ

[Journal Article] クロマチンと病態2005