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Wakai Toshifumi  若井 俊文

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WAKAI Toshifumi  若井 俊文

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Researcher Number 50372470
Other IDs
Affiliation (Current) 2025: 新潟大学, 医歯学系, 教授
Affiliation (based on the past Project Information) *help 2012 – 2025: 新潟大学, 医歯学系, 教授
2009 – 2011: 新潟大学, 医歯学総合病院, 講師
2009: Niigata University, 医歯学総合病院, 助教
2007: Niigata University, Medical and Dental Hospital, Assistant Professor
2005 – 2006: Niigata University, Medical and Dental Hospital, Fellow, 医歯学総合病院, 医員
2004: Niigata University, Medical and Dental Hospital, Assistant, 医歯学総合病院, 助手
Review Section/Research Field
Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Except Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Human pathology / Gastroenterology / Basic Section 52040:Radiological sciences-related / Medium-sized Section 62:Applied informatics and related fields … More / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / General surgery / Pediatric surgery / Hygiene / Public health/Health science Less
Keywords
Principal Investigator
高次元データ解析 / 癌遺伝子異常 / 胆道癌 / 脂質メディエーター / Hepatocellular carcinoma / small interfeing RNA / Anchorage-independent growth / HepG2 / CEACAM1 / Prognosis … More / Immunohistochemistry / Cytokeratin / Micrometastasis / Lymph node metastasis / Metastasis / Ampullary carcinoma / 上皮内癌 / p53-binding protein 1 / 胆管癌 / 胆道外科学 / ゲ ノム解析 / 16S rRNA遺伝子解析 / 発癌メカニズム / DNA付加体 / ゲノム解析 / 変異シグネチャー解析 / 腫瘍内細菌叢 / 高次元データ解析システム / ゲノム / マイクロサテライト不安定性 / 腫瘍変異負荷 / ゲノム高次元データ解析 / 人工知能 / 深層学習 / 消化器癌 / 体液 / 細菌叢 / バイオマーカー / 薬物療法 / 伝播経路 / 消化器 / ヒト共生細菌叢 / セラミド / リピドミクス解析 / リンパ行性転移 / リンパ行性進展転移 / 細胞情報伝達機構 / 胆道疾患 / 胆汁酸 / スフィンゴシン-1-リン酸 / 転移能 / 膵癌 / 細胞増殖能 / B/6系マウス / CRISPR/Cas9 / リンパ管浸潤 / 細胞外基質 / リンパ管新生 / ダブルノックアウトマウス / 膵臓外科学 / Cytoplasmic domain / Transmembrane domain / Neoplasm metastasis / Isoform / Small interfering RNA / Anticytokeratin / 予後 / 免疫組織化学 / 抗サイトケラチン抗体 / サイトケラチン / 微小転移 / リンパ節転移 / 十二指腸乳頭部癌 / Micrometastases / Lymph node metastases / Metastases / Anticytokeratin antibody / DNA二重鎖切断 / γ-H2AX / DNA損傷修復機構 / field carcinogenesis / 表層拡大進展 / 早期DNA損傷修復機構 / 53-binding protein 1 / アポトーシス / DNA損傷修復応答 / 胆管切離断端 … More
Except Principal Investigator
大腸癌 / 免疫組織化学 / スフィンゴシン-1-リン酸 / 脂質メディエーター / 食道癌 / 胃癌 / 膵癌 / S1P / 化学療法 / 術前化学療法 / 薬剤耐性 / リンパ節転移 / DNA二重鎖切断 / Radiomics / Radiogenomics / 変異シグネチャー / 乳癌 / mutational signature / スフィンゴシンキナーゼ1型 / NQO1 / 炎症性発癌 / 胆嚢癌 / 予測モデル / 直腸癌 / FISH / HER2 / 抗HER2療法 / 治療 / スフィンゴシン-1-リン酸 / 癌遺伝子パネル / SphK1 / 薬物療法抵抗性 / 大腸癌肝転移 / 発癌 / 遺伝子変異 / CRISPR/Cas9 / 遺伝子解析 / 発癌メカニズム / 肝細胞癌 / pSphK1 / 免疫組織化学染色 / 肝転移 / 免疫染色 / 簇出 / p62 / Nrf2 / 食道外科学 / γH2AX / 蛍光二重免疫染色 / 肝がん / DNA損傷応答 / 潰瘍性大腸炎 / 食道扁平上皮癌 / リンパ管侵襲 / 胆道外科学 / 大腸がん / 粘液形質 / BRAF変異 / IRI蛍光法 / 自家移植 / 脂質メディエータ / 血管新生 / 膵島移植 / 放射線・病理画像診断 / バーチャルスライド / 病理画像 / CT画像 / 腫瘍遺伝子変異量 / テクスチャ解析 / 肺癌 / 遺伝子変異解析 / 胆道癌 / 側方リンパ節転移 / 側方リンパ節 / Random forest / 機械学習 / 術前治療 / 癌遺残形式 / 遺伝子多型 / 位相角 / 生体インピーダンス法 / 乳がん / 免疫チェックポイント阻害薬 / 相同組換え修復欠損 / トリプルネガティブ / パスウェイ解析 / 遺伝子異常 / 胆囊癌 / Heterogeneity / 生存解析 / 外科切除 / HER2陽性胆嚢癌 / 遺伝子パネル検査 / 塩基置換 / 固形癌 / 消化器癌 / バイオインフォマティクス / ターゲット遺伝子パネル検査 / 化学放射線療法 / 臨床的完全奏効 / 腫瘍変異負荷量 / pathway解析 / サーベイランス / Watch and Wait / 術前化学放射線療法 / 免疫微小環境 / スフィンゴシン‐1-リン酸 / 腫瘍免疫微小環境 / HER2陽性胃癌 / ERBB2 / trastuzumab / 癌遺伝子解析パネル / HER2陽性 / 門脈 / 直腸浸潤 / 直腸間膜リンパ節 / 直腸間膜リンパ節腫大 / 腹膜癌 / 血行性肝転移 / 直腸間膜リンパ節転移 / 卵巣癌 / 精密医療 / データベース / がんゲノム / トリプルネガティブ乳癌 / 癌代謝 / homologous recombination / 白金系抗癌剤 / がん遺伝子パネル検査 / 相同組換え修復 / 抗がん剤耐性 / 脈管侵襲 / セラミド / TCGA / スフィンゴ脂質 / 腫瘍内リンパ球浸潤 / 低分化胞巣 / TMB-H / SMAD4 / SMAD2 / ACVR2A / TGFBR2 / TGF-β / 転写メディエーター / MED12 / スフィンゴシン‐1‐リン酸 / 癌微小環境 / 胆管生検試料 / 診断 / 生検 / 胆管癌 / 53BP1 / 肝再発 / 再発形式 / 腫瘍関連マクロファージ / マクロファージ遊走阻止因子 / 腫瘍微小環境 / 薬物療法効果予測 / 肝臓外科学 / 薬剤抵抗性 / スフィンゴシン1リン酸 / 炎症性腸疾患 / 相同組み換え修復 / ゲノムシーケンス / BRCA / アクチビン受容体 / 次世代シークエンサー / Hypermutation / アクチビン2型受容体 / MKN74 ヒト胃癌細胞 / CRISPR-Cas9 / アクチビン受容体2A型 / マイクロサテライト不安定 / 遺伝子関連タンパク / ミスマッチ修復遺伝子 / p53 / 発生メカニズム / de novo癌 / HCV / 抗癌剤耐性獲得 / 腫瘍増殖能亢進 / リン酸化p62 / KEAP1 / オートファジー / リンパ行性進展 / 肝臓学 / 消化器内科 / シスプラチン / エクソソーム / スフィンゴシンキナーゼ1型 / リピドミクス解析 / リンパ管新生 / スフィンゴシンキナーゼ / RBP / RTP / 末梢静脈栄養 / Rapid turnover protein / インスリン抵抗性 / タンパク代謝 / 低脂肪経腸栄養剤 / 乳び胸 / 経腸栄養 / CRP / 術後回復 / 脂肪乳剤 / 静脈栄養 / カルニチン / prognosis / surgery / anticytokeratin antibody / immunohistochemistry / hepatic micrometastasis / micrometastasis / liver metastasis / colorectal carcinoma / 生存分析 / 抗サイトケラチン20抗体 / 抗サイトケラチン抗体 / 肝内微小転移 / 微小転移 / AE1/AE3染色 / TUNEL / Ki-67 / 細胞増殖活性 / アポトーシス / 増殖能 / PEPT-2 / PEPT-1 / アミノレブリン酸 / 光線力学診断 / 5-ALA / CAM5.2モノクローナル抗体 / HE染色 / 大腸粘膜下層浸潤癌 / 内視鏡的粘膜切除術 / 粘膜下層浸潤癌 / Keap1 / KRAS / 抗癌剤耐性 / 治療抵抗性 / 酸化ストレス / 術前補助化学療法 / 消化管間質腫瘍 / SSA/P / 大腸鋸歯状病変 / DNA損傷修復応答 / 鋸歯状病変 / 腺腫の癌化 / 大腸癌の発生 / 遠隔転移 / 病期 / CEACAM1 / CEACAM6 / 接着因子 / CEACAM / 肝芽腫 / drug resistance / hepatocellular carcinoma / sorafenib / TGF-beta / 分子標的薬 / ソラフェニブ / リンパ節転移個数 / lymph node ratio / プロテオミクス解析 / チリ / 国際情報交換 / 特異蛋白質 / 腫瘍マーカー / 質量分析 / 特異蛋白 / スクリーニング / 胆嚢がん / dysplasia / 扁平上皮癌 / 飲酒 / 喫煙 / 環境因子 / マッチングデータ / 条件付きロジスティック回帰分析 / 腺癌 / ホットスポット分析 / ロジスティック回帰分析 / 窒素化合物 / リスク因子 / 中国疫学調査 / 医療情報学 / 集団検診 / 地域保健 / 保健医療行政 / 健康管理 / 国際保健学 / 疫学 / 根治手術 / 癌の転移 / 肝切除術 / モノクローナル抗体 / 静脈侵襲 / 肝内進展様式 Less
  • Research Projects

    (61 results)
  • Research Products

    (263 results)
  • Co-Researchers

    (87 People)
  •  消化器癌の全ゲノム解析とRNAシークエンス解析による治療抵抗性分子制御機構の解明Principal Investigator

    • Principal Investigator
      若井 俊文
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Radiogenomics解析による胆道癌リンパ節転移の新規高精度予測モデルの開発

    • Principal Investigator
      坂田 純
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  放射線・病理画像テクスチャ解析を用いた肺癌の腫瘍遺伝子変異量予測モデルの開発

    • Principal Investigator
      山崎 元彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Niigata University
  •  脂質メディエータS1Pの血管新生作用を応用した新たな移植膵島生着率改善の試み

    • Principal Investigator
      三浦 宏平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Niigata University
  •  BRAF変異陽性の大腸癌における分子病理学的特徴を加味した新しい分類法の確立

    • Principal Investigator
      中野 麻恵
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  トリプルネガティブ乳癌における変異シグネチャー解析の臨床病理学的意義の解明

    • Principal Investigator
      土田 純子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Niigata University
  •  大腸癌の変異シグネチャーを予測するRadiogenomics解析法の確立

    • Principal Investigator
      松本 瑛生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  食道癌患者における生体インピーダンス法で測定される位相角の臨床的意義の解明

    • Principal Investigator
      市川 寛
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  食道癌術前化学療法の治療効果予測を目指したNQO1遺伝子多型の臨床的意義の解明

    • Principal Investigator
      石川 卓
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  放射線画像・遺伝子解析を統合した食道癌術前治療後の癌遺残形式予測モデルの開発

    • Principal Investigator
      宗岡 悠介
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Radiogenomicsによる直腸癌側方リンパ節転移の高精度予測モデルの開発

    • Principal Investigator
      中野 雅人
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  腫瘍内細菌叢が引き起こす癌遺伝子異常の同定と変異シグネチャー解析による要因の解明Principal Investigator

    • Principal Investigator
      若井 俊文
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  Development of Artificial Intelligence by Deep Learning Based on Genomic High-Dimensional Data Analysis System for Gastrointestinal CancerPrincipal Investigator

    • Principal Investigator
      WAKAI TOSHIFUMI
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Establishment of a new surveillance method for clinical complete response after chemoradiotherapy in patients with rectal cancer

    • Principal Investigator
      Shimada Yoshifumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Establishment of classification for base substitution pattern and assessment for clinical implication of mutational signature in solid tumors

    • Principal Investigator
      Hirose Yuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Comprehensive cancer-related pathway analysis of genetic abnormalities in HER2-positive gallbladder cancer and their clinical significance

    • Principal Investigator
      Sakata Jun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Clinical Significance of Lipid Mediator in the tumor Microenvironment of Pancreatic Adenocarcinoma

    • Principal Investigator
      TAKIZAWA KAZUYASU
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  New metastatic pathway via mesenteric lymph node involvement in ovarian cancer liver metastasis

    • Principal Investigator
      Nakano Masato
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Clinical significance of comprehensive genomic analysis in HER2 positive gastric cancer

    • Principal Investigator
      Usui Kenji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Elucidation of the interaction between human commensal bacterial flora and host genetic alterations in the digestive tractPrincipal Investigator

    • Principal Investigator
      Wakai Toshifumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  The role of lipid mediator in the tumor immune microenvironment of breast cancer and its therapeutic application

    • Principal Investigator
      Nagahashi Masayuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Hyogo Medical University
      Niigata University
  •  The new classification of colorectal cancer focusing on differences of molecular mechanisms in TGF-b signal pathway

    • Principal Investigator
      Shimada Yoshifumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  The role of lipid mediators for lymphvascular invasion in hepatocellular carcinoma and its clinical significance

    • Principal Investigator
      Hirose Yuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Clinical significance of defective DNA double-strand break repair pathway in gastric cancer

    • Principal Investigator
      Katada Tomohiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Mechanisms of cancer metabolism and drug resistance regulated by S1P in triple negative breast cancer

    • Principal Investigator
      Nagahashi Masayuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  High-dimensional data analysis platform realizing cancer genome medicine

    • Principal Investigator
      Okuda Shujiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 62:Applied informatics and related fields
    • Research Institution
      Niigata University
  •  Molecular mechanism of de novo colorectal carcinoma

    • Principal Investigator
      Ajioka Yoichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Niigata University
  •  The role and clinical relevance of Activin receptor type 2A mutation in gastric cancer

    • Principal Investigator
      Yuza Kizuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Clinical significance of pathogenic germline BRCA1/2 mutations in gastric cancer

    • Principal Investigator
      Takizawa Kazuyasu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Role of lipid mediator in colitis-associated cancer

    • Principal Investigator
      Kameyama Hitoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Elucidation of clinical significance and chemotherapy resistance mechanism of NAD(P)H:quinone oxidoreductase 1 (NQO1) expression for colorectal liver metastasis

    • Principal Investigator
      Nakano Mae
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Elucidation and clinical significance of tumor microenvironmental mechanism of pancreatic cancer through tumor-associated macrophages

    • Principal Investigator
      Takano Kabuto
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Establishment of a new methodology to distinguish between benign and malignant lesions in bile duct biopsy specimens based on an early repair mechanism for DNA double-strand breaks

    • Principal Investigator
      Ishikawa Hirosuke
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Roles and clinical significance of lipid mediator producing enzymes in the formation of the tumor microenvironment of pancreatic cancer

    • Principal Investigator
      Nakajima Masato
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  The mechanism of exosome-mediated drug resistance in hepatoma cells

    • Principal Investigator
      Yasunobu MATSUDA
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Niigata University
  •  Clinical significance of sphingosine-1-phosphate and sphingosine kinase 1 in lymphatic spread of esophageal cancer

    • Principal Investigator
      Ichikawa Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Elucidation of molecular mechanism through autophagy in carcinogenesis of hepatocellular carcinoma

    • Principal Investigator
      Sakata Jun
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Elucidation of a novel cell signaling mechanism by lipid mediators and bile acids in biliary diseasesPrincipal Investigator

    • Principal Investigator
      WAKAI TOSHIFUMI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitine

    • Principal Investigator
      Koyama Yu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Niigata University
  •  Clinical Significance and elucidation of molecular regulation mechanism of lipid mediators in invasion and metastatic ability of gastric cancer

    • Principal Investigator
      Hanyu Takaaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Elucidation of molecular mechanism of lipid mediator involved in metastatic ability of biliary tract cancer / pancreatic cancer and clinical applicationPrincipal Investigator

    • Principal Investigator
      WAKAI TOSHIFUMI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  The role of MED12 expression in molecular mechanism of drug resistance of colorectal cancer

    • Principal Investigator
      Yoshifumi Shimada
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Significance of DNA damage response in histogenesis of colorectal carcinoma

    • Principal Investigator
      AJIOKA Yoichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Niigata University
  •  Analysis of gene expression involved in the prognosis and occurrence site of gastrointestinal stromal tumors

    • Principal Investigator
      ISHIKAWA Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Oxidative stress signaling as the molecular mechanism of chemo-resistance in esophageal cancer

    • Principal Investigator
      KOSUGI Shin-ichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway

    • Principal Investigator
      KAMEYAMA Hitoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Biological evaluation and significance of tumor budding using fluorescence immunohistochemistry in pT1b colorectal cancer

    • Principal Investigator
      NOGAMI Hitoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Prediction of Chemotherapy Response to Pancreatic Cancer Using Photodynamic diagnosis

    • Principal Investigator
      MINAGAWA Masahiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Assessment of proliferation and apoptotic rate of tumor budding cells in pancreatic ductal adenocarcinoma.

    • Principal Investigator
      Takizawa Kazuyasu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Molecular Analysis of Cytokine-mediated Sorafenib Resistance

    • Principal Investigator
      MATSUDA YASUNOBU
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Niigata University
  •  Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinomaPrincipal Investigator

    • Principal Investigator
      WAKAI Toshifumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Molecular Analysis of CEACAM Family in Hepatoblastoma

    • Principal Investigator
      NAKAYA KENGO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatric surgery
    • Research Institution
      Niigata University
  •  Significance of DNA damage response in cancerization in ulcerative colitis

    • Principal Investigator
      AJIOKA Yoichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Niigata University
  •  SEARCHING OF SPECIFIC PROTEINS PRODUCED IN GALLBLADDER CANCER TISSUES FOR THE EARLY DETECTION OF THE CANCER

    • Principal Investigator
      TSUCHIYA Yasuo
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Niigata University of Health and Welfare
  •  A Proposal of New Nodal Classification in Gallbladder Cancer

    • Principal Investigator
      SAKATA Jun
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Epidemiological study for identifying risk factors of esophageal adenocarcinoma in north China.

    • Principal Investigator
      AKAZAWA Kohei
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Public health/Health science
    • Research Institution
      Niigata University
  •  Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinomaPrincipal Investigator

    • Principal Investigator
      WAKAI Toshifumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Mode of Hepatic Spread from Gallbladder Carcinoma : An Immunohistochemical Analysis of 42 Hepatectomized Specimens

    • Principal Investigator
      SHIRAI Yoshio
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  The mechanism and clinical significance of loss of CEACAM1 expression in hepatocellular carcinomaPrincipal Investigator

    • Principal Investigator
      WAKAI Toshifumi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Clinical significance of lymph node micrometastasis in ampullary carcinomaPrincipal Investigator

    • Principal Investigator
      WAKAI Toshifumi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  Colorectal Carcinoma liver Metastases : Immunohistochemical Detection of Hepatic Micrometastases Using Monoclonal Anticytokeratin Antibody

    • Principal Investigator
      SHIRAI Yoshio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      NIIGATA UNIVERSITY

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2007 2006 2005 2003 Other

All Journal Article Presentation Patent

  • [Journal Article] Mucin phenotype and genetic alterations in non-V600E BRAF-mutated colorectal cancer2024

    • Author(s)
      Ozeki Hikaru、Shimada Yoshifumi、Nakano Mae、Kondo Shuhei、Ohashi Riuko、Miwa Yamato、Yamai Daisuke、Matsumoto Akio、Abe Kaoru、Tajima Yosuke、Ichikawa Hiroshi、Sakata Jun、Takii Yasumasa、Sugai Mika、Nagai Takahiro、Ling Yiwei、Okuda Shujiro、Wakai Toshifumi
    • Journal Title

      Human Pathology

      Volume: 145 Pages: 71-79

    • DOI

      10.1016/j.humpath.2024.02.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-23K08189
  • [Journal Article] Clinical Significance of Phosphorylated Sphingosine Kinase 1 Expression in Pancreatic Ductal Adenocarcinoma2023

    • Author(s)
      Nagaro H, Ichikawa H, Takizawa K, Nagahashi M, Abe S, Hirose Y, Moro K, Miura K, Nakano M, Shimada Y, Sakata J, Wakai T
    • Journal Title

      Anticancer Res

      Volume: 43 Issue: 9 Pages: 3969-3977

    • DOI

      10.21873/anticanres.16584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Journal Article] Axillary cutaneous metastasis of colon cancer with microsatellite instability-high and BRAF V600E mutation treated with curative-intent surgery: a case report2023

    • Author(s)
      Yamai Daisuke、Shimada Yoshifumi、Ozeki Hikaru、Matsumoto Akio、Abe Kaoru、Tajima Yosuke、Nakano Mae、Ichikawa Hiroshi、Sakata Jun、Wakai Toshifumi
    • Journal Title

      Surgical Case Reports

      Volume: 9 Issue: 1 Pages: 196-196

    • DOI

      10.1186/s40792-023-01780-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08189, KAKENHI-PROJECT-21H02998
  • [Journal Article] Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex2023

    • Author(s)
      Kurusu Reo、Fujimoto Yuki、Morishita Hideaki、Noshiro Daisuke、Takada Shuhei、Yamano Koji、Tanaka Hideaki、Arai Ritsuko、Kageyama Shun、Funakoshi Tomoko、Komatsu-Hirota Satoko、Taka Hikari、Kazuno Saiko、Miura Yoshiki、Koike Masato、Wakai Toshifumi、Waguri Satoshi、Noda Nobuo N.、Komatsu Masaaki
    • Journal Title

      Developmental Cell

      Volume: - Issue: 13 Pages: 1189-1205

    • DOI

      10.1016/j.devcel.2023.04.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K23841, KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-22K06300, KAKENHI-PROJECT-23K05683, KAKENHI-PROJECT-23K06323, KAKENHI-ORGANIZER-19H05705, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-21H02998, KAKENHI-PROJECT-23K27134, KAKENHI-PROJECT-23K27351, KAKENHI-PROJECT-23H05327
  • [Journal Article] Clinical significance of metastatic tumor deposit foci in rectal cancer in the lateral pelvic lymph node area2023

    • Author(s)
      Yamai Daisuke、Shimada Yoshifumi、Nakano Masato、Ozeki Hikaru、Matsumoto Akio、Abe Kaoru、Tajima Yosuke、Nakano Mae、Ichikawa Hiroshi、Sakata Jun、Nagai Takahiro、Ling Yiwei、Okuda Shujiro、Watanabe Gen、Nogami Hitoshi、Maruyama Satoshi、Takii Yasumasa、Wakai Toshifumi
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 28 Issue: 10 Pages: 1388-1397

    • DOI

      10.1007/s10147-023-02391-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-22K08890
  • [Journal Article] Gene panel testing detects important genetic alterations in ulcerative colitis-associated colorectal neoplasia2022

    • Author(s)
      Shimada Y, Nakano M, Mizuno KI, Yokoyama J, Matsumoto A, Tanaka K, Oyanagi H, Nakano M, Hirose Y, Ichikawa H, Sakata J, Kameyama H, Takii Y, Sugai M, Ling Y, Takeuchi S, Okuda S, Terai S, Ajioka Y, Wakai T.
    • Journal Title

      Oncology Letters

      Volume: 24 Issue: 6 Pages: 442-442

    • DOI

      10.3892/ol.2022.13562

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08750, KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-20K09003
  • [Journal Article] Differential analysis of microbiomes in mucus and tissues obtained from colorectal cancer patients.2022

    • Author(s)
      Tajima Y, Okuda S, Hanai T, Hiro J, Masumori K, Koide Y, Kamiya T, Cheong Y, Inaguma G, Shimada Y, Wakai T, Takihara H, Akimoto S, Matsuoka H, Uyama I, Suda K.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 18193-18193

    • DOI

      10.1038/s41598-022-21928-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Journal Article] Unveiling microbiome profiles in human inner body fluids and tumor tissues with pancreatic or biliary tract cancer.2022

    • Author(s)
      Okuda S, Hirose Y, Takihara H, Okuda A, Ling Y, Tajima Y, Shimada Y, Ichikawa H, Takizawa K, Sakata J, Wakai T.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 8766-8766

    • DOI

      10.1038/s41598-022-12658-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19556, KAKENHI-PROJECT-21K17850, KAKENHI-ORGANIZER-21H05107
  • [Journal Article] Exosomal p38 Mitogen-activated Protein Kinase Promotes Tumour Repopulation in TP53-mutated Bile Duct Cancer Cells2022

    • Author(s)
      大澤まみ、松田康伸、坂田純、若井俊文
    • Journal Title

      Anticancer Res

      Volume: 42 Issue: 2 Pages: 745-757

    • DOI

      10.21873/anticanres.15533

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08365, KAKENHI-PROJECT-21H02998
  • [Journal Article] Histopathological characteristics and artificial intelligence for predicting tumor mutational burden-high colorectal cancer2021

    • Author(s)
      Shimada Yoshifumi、Okuda Shujiro、Watanabe Yu、Tajima Yosuke、Nagahashi Masayuki、Ichikawa Hiroshi、Nakano Masato、Sakata Jun、Takii Yasumasa、Kawasaki Takashi、Homma Kei-ichi、Kamori Tomohiro、Oki Eiji、Ling Yiwei、Takeuchi Shiho、Wakai Toshifumi
    • Journal Title

      Journal of Gastroenterology

      Volume: - Issue: 6 Pages: 547-559

    • DOI

      10.1007/s00535-021-01789-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123, KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-21H02998, KAKENHI-PROJECT-21K17850
  • [Journal Article] Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer.2021

    • Author(s)
      Okuda S, Shimada Y, Tajima Y, Yuza K, Hirose Y, Ichikawa H, Nagahashi M, Sakata J, Ling Y, Miura N, Sugai M, Watanabe Y, Takeuchi S, Wakai T
    • Journal Title

      Comput Struct Biotechnol J

      Volume: 19 Pages: 3330-3338

    • DOI

      10.1016/j.csbj.2021.05.049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22651, KAKENHI-PROJECT-21K17850
  • [Journal Article] Dysregulation of sphingolipid metabolic enzymes leads to high levels of sphingosine‐1‐phosphate and ceramide in human hepatocellular carcinoma2021

    • Author(s)
      Miura Kohei、Nagahashi Masayuki、Prasoon Pankaj、Hirose Yuki、Kobayashi Takashi、Sakata Jun、Abe Manabu、Sakimura Kenji、Matsuda Yasunobu、Butash Ali L.、Katsuta Eriko、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      Hepatology Research

      Volume: 51 Issue: 5 Pages: 614-626

    • DOI

      10.1111/hepr.13625

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18K08672
  • [Journal Article] Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer2021

    • Author(s)
      Ikarashi Mayuko、Tsuchida Junko、Nagahashi Masayuki、Takeuchi Shiho、Moro Kazuki、Toshikawa Chie、Abe Shun、Ichikawa Hiroshi、Shimada Yoshifumi、Sakata Jun、Koyama Yu、Sato Nobuaki、Hait Nitai C.、Ling Yiwei、Okuda Shujiro、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 24 Pages: 13367-13367

    • DOI

      10.3390/ijms222413367

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03714, KAKENHI-PROJECT-21K17850
  • [Journal Article] Urokinase-type Plasminogen Activator Is a Therapeutic Target for Overcoming Sorafenib Resistance in Hepatoma Cells2021

    • Author(s)
      Osawa M, Matsuda Y, Kinoshita Y, Wakai T
    • Journal Title

      Anticancer Res

      Volume: 41 Issue: 2 Pages: 645-660

    • DOI

      10.21873/anticanres.14816

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Journal Article] NQO1 as a Marker of Chemosensitivity and Prognosis for Colorectal Liver Metastasis2021

    • Author(s)
      Hirose Y, Sakata J, Kobayashi T, Miura K, Yuza K, Nakano M, Ichikawa H, Nagahashi M, Shimada Y, Kameyama H, Wakai T
    • Journal Title

      Anticancer Res

      Volume: 41 Issue: 3 Pages: 1563-1570

    • DOI

      10.21873/anticanres.14916

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Journal Article] ASO Author Reflections: Clinical Significance of Mesenteric Lymph Node Involvement in Patients with Ovarian Cancer2021

    • Author(s)
      Shimada Yoshifumi、Tanaka Kana、Nishino Koji、Yoshihara Kosuke、Nakano Masato、Kameyama Hitoshi、Enomoto Takayuki、Wakai Toshifumi
    • Journal Title

      Annals of Surgical Oncology

      Volume: 28 Issue: 12 Pages: 7614-7615

    • DOI

      10.1245/s10434-021-09919-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09116
  • [Journal Article] Clinical Significance of Mesenteric Lymph Node Involvement in the Pattern of Liver Metastasis in Patients with Ovarian Cancer2021

    • Author(s)
      Tanaka Kana、Shimada Yoshifumi、Nishino Koji、Yoshihara Kosuke、Nakano Masato、Kameyama Hitoshi、Enomoto Takayuki、Wakai Toshifumi
    • Journal Title

      Annals of Surgical Oncology

      Volume: 28 Issue: 12 Pages: 7606-7613

    • DOI

      10.1245/s10434-021-09899-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09116, KAKENHI-PROJECT-20K21647
  • [Journal Article] Sphingosine Kinase 1 is Associated With Immune Cell Related Gene Expressions in Human Breast Cancer2020

    • Author(s)
      Junko Tsuchida, Masayuki Nagahashi, Masato Nakajima, Eriko Katsuta, Omar M. Rashid, Qianya Qi, Li Yan, Shujiro Okuda, Kazuaki Takabe, Toshifumi Wakai
    • Journal Title

      Journal of Surgical Research

      Volume: 15 Pages: 645-656

    • DOI

      10.1016/j.jss.2020.06.057

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18049, KAKENHI-PROJECT-19H03714
  • [Journal Article] Genetic profiling for diffuse type and genomically stable subtypes in gastric cancer2020

    • Author(s)
      Ling Yiwei、Watanabe Yu、Nagahashi Masayuki、Shimada Yoshifumi、Ichikawa Hiroshi、Wakai Toshifumi、Okuda Shujiro
    • Journal Title

      Computational and Structural Biotechnology Journal

      Volume: 18 Pages: 3301-3308

    • DOI

      10.1016/j.csbj.2020.10.021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123, KAKENHI-PROJECT-19K20397
  • [Journal Article] RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer2020

    • Author(s)
      Matsumoto A, Shimada Y, Nakano M, Oyanagi H, Tajima Y, Nakano M, Kameyama H, Hirose Y, Ichikawa H, Nagahashi M, Nogami H, Maruyama S, Takii Y, Ling Y, Okuda S, Wakai T.
    • Journal Title

      Oncology Reports

      Volume: 43 Pages: 1853-1862

    • DOI

      10.3892/or.2020.7561

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-17K10624, KAKENHI-PROJECT-19K20397
  • [Journal Article] Hyperbilirubinemia predicts the infectious complications after esophagectomy for esophageal cancer2019

    • Author(s)
      Muneoka Yusuke、Ichikawa Hiroshi、Kosugi Shin-ichi、Hanyu Takaaki、Ishikawa Takashi、Kano Yosuke、Shimada Yoshifumi、Nagahashi Masayuki、Sakata Jun、Kobayashi Takashi、Kameyama Hitoshi、Akazawa Kohei、Wakai Toshifumi
    • Journal Title

      Annals of Medicine and Surgery

      Volume: 39 Pages: 16-21

    • DOI

      10.1016/j.amsu.2019.02.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04093, KAKENHI-PROJECT-16K10491
  • [Journal Article] Phospho-Sphingosine Kinase 1 Expression in Lymphatic Spread of Esophageal Squamous Cell Carcinoma2019

    • Author(s)
      Nemoto Mariko、Ichikawa Hiroshi、Nagahashi Masayuki、Hanyu Takaaki、Ishikawa Takashi、Kano Yosuke、Muneoka Yusuke、Wakai Toshifumi
    • Journal Title

      Journal of Surgical Research

      Volume: 234 Pages: 123-131

    • DOI

      10.1016/j.jss.2018.09.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Journal Article] SMAD4 alteration associates with invasive-front pathological markers and poor prognosis in colorectal cancer2019

    • Author(s)
      Oyanagi H, Shimada Y, Nagahashi M, Ichikawa H, Tajima Y, Abe K, Nakano M, Kameyama H, Takii Y, Kawasaki T, Homma KI, Ling Y, Okuda S, Takabe K, Wakai T.
    • Journal Title

      Histopathology

      Volume: 74 Issue: 6 Pages: 873-882

    • DOI

      10.1111/his.13805

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08612
  • [Journal Article] Clinical application of ceramide in cancer treatment2019

    • Author(s)
      Kazuki Moro, Masayuki Nagahashi, Emmanuel Gabriel, Kazuaki Takabe & Toshifumi Wakai
    • Journal Title

      Breast Cancer

      Volume: 26 Issue: 4 Pages: 407-415

    • DOI

      10.1007/s12282-019-00953-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Journal Article] Pathogenic Germline BRCA1/2 Mutations and Familial Predisposition to Gastric Cancer2018

    • Author(s)
      Ichikawa H, Wakai T, Nagahashi M, Shimada Y, Hanyu T, Kano Y, Muneoka Y, Ishikawa T, Takizawa K, Tajima Y, Sakata J, Kobayashi T, Kameyama H, Yabusaki H, Nakagawa S, Sato N, Kawasaki T, Homma K, Okuda S, Lyle S, Takabe K
    • Journal Title

      JCO precision oncology

      Volume: 5 Issue: 15_suppl Pages: 1-8

    • DOI

      10.1200/jco.2018.36.15_suppl.e13618

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10580
  • [Journal Article] Expression of phosphorylated sphingosine kinase 1 is associated with diffuse type and lymphatic invasion in human gastric cancer.2018

    • Author(s)
      Hanyu T, Nagahashi M, Ichikawa H, Ishikawa T, Kobayashi T, Wakai T.
    • Journal Title

      Surgery

      Volume: [Epub ahead of print] Issue: 6 Pages: 1301-1306

    • DOI

      10.1016/j.surg.2017.11.024

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10087
  • [Journal Article] Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis2018

    • Author(s)
      Hirose Y, Nagahashi M, Katsuta E, Yuza K, Miura K, Sakata J, Kobayashi T, Ichikawa H, Shimada Y, Kameyama H, McDonald KA, Takabe K, Wakai T
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 10814-10814

    • DOI

      10.1038/s41598-018-29144-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Journal Article] Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression2018

    • Author(s)
      Yuza Kizuki、Nakajima Masato、Nagahashi Masayuki、Tsuchida Junko、Hirose Yuki、Miura Kohei、Tajima Yosuke、Abe Manabu、Sakimura Kenji、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      Journal of Surgical Research

      Volume: 232 Pages: 186-194

    • DOI

      10.1016/j.jss.2018.06.019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K10692
  • [Journal Article] Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer.2018

    • Author(s)
      Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Takabe K, Wakai T.
    • Journal Title

      Journal of surgical research

      Volume: 231 Pages: 323-330

    • DOI

      10.1016/j.jss.2018.05.085

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Journal Article] Genomic characterization of colitis-associated colorectal cancer.2018

    • Author(s)
      Kameyama H, Nagahashi M, Shimada Y, Tajima Y, Ichikawa H, Nakano M, Sakata J, Kobayashi T, Narayanan S, Takabe K, Wakai T.
    • Journal Title

      World journal of surgical oncology

      Volume: 16 Issue: 1 Pages: 121-121

    • DOI

      10.1186/s12957-018-1428-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Journal Article] Next generation sequencing-based gene panel tests for the management of solid tumors.2018

    • Author(s)
      Nagahashi M, Shimada Y, Ichikawa H, Kameyama H, Takabe K, Okuda S, Wakai T.
    • Journal Title

      Cancer Sci.

      Volume: 110 Issue: 1 Pages: 6-15

    • DOI

      10.1111/cas.13837

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Journal Article] The role of sphingosine-1-phosphate in inflammation and cancer progression2018

    • Author(s)
      Nagahashi Masayuki、Abe Manabu、Sakimura Kenji、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 12 Pages: 3671-3678

    • DOI

      10.1111/cas.13802

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Journal Article] Feasibility of restorative proctocolectomy in patients with ulcerative colitis-associated lower rectal cancer: A retrospective study.2018

    • Author(s)
      Hotta S, Shimada Y, Nakano M, Yamada S, Abe K, Oyanagi H, Yagi R, Tajima Y, Nakano M, Kameyama H, Nagahashi M, Sakata J, Kobayashi T, Wakai T.
    • Journal Title

      Asian Journal of Surgery

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Journal Article] Feasibility of restorative proctocolectomy in patients with ulcerative colitis-associated lower rectal cancer: A retrospective study.2018

    • Author(s)
      Hotta S, Shimada Y, Nakano M, Yamada S, Abe K, Oyanagi H, Yagi R, Tajima Y, Nakano M, Kameyama H, Nagahashi M, Sakata J, Kobayashi T, Wakai T.
    • Journal Title

      Asian Journal of Surgery

      Volume: 印刷中 Issue: 1 Pages: 267-273

    • DOI

      10.1016/j.asjsur.2018.01.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10130
  • [Journal Article] Association between poorly differentiated clusters and efficacy of 5-fluorouracil-based adjuvant chemotherapy in stage III colorectal cancer.2017

    • Author(s)
      Tajima Y, Shimada Y, Kameyama H, Yagi R, Okamura T, Kobayashi T, Kosugi SI, Wakai T.
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 47 Issue: 4 Pages: 313-320

    • DOI

      10.1093/jjco/hyw209

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10130
  • [Journal Article] Hypermutation and microsatellite instability in gastrointestinal cancers2017

    • Author(s)
      Yuza Kizuki、Nagahashi Masayuki、Watanabe Satoshi、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 67 Pages: 112103-112115

    • DOI

      10.18632/oncotarget.22783

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10579
  • [Journal Article] Relevance of Dissection of the Posterior Superior Pancreaticoduodenal Lymph Nodes in Gallbladder Carcinoma.2017

    • Author(s)
      Sakata J,Kobayashi T,Tajima Y,Ohashi T,Hirose Y,Takano K,Takizawa K,Miura K,Wakai T
    • Journal Title

      Ann Surg Oncol.

      Volume: 24 Issue: 9 Pages: 2474-2481

    • DOI

      10.1245/s10434-017-5939-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Journal Article] 癌と宿主におけるスフィンゴシン-1-リン酸の役割2017

    • Author(s)
      永橋 昌幸,若井 俊文
    • Journal Title

      BIO Clinica

      Volume: 32 Pages: 397-404

    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Journal Article] Prognostic heterogeneity of the seventh edition of UICC Stage III gallbladder carcinoma: Which patients benefit from surgical resection?2017

    • Author(s)
      Sakata J, Kobayashi T, Ohashi T, Hirose Y, Takano K, Takizawa K, Miura K, Ishikawa H, Toge K, Yuza K, Soma D, Ando T, Wakai T
    • Journal Title

      Eur J Surg Oncol.

      Volume: 43 Issue: 4 Pages: 780-787

    • DOI

      10.1016/j.ejso.2017.01.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-16K15610
  • [Journal Article] Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer2017

    • Author(s)
      Shimada Y, Kameyama H, Nagahashi M, Ichikawa H, Muneoka Y, Yagi R, Tajima Y, Okamura T, Nakano M, Sakata J, Kobayashi T, Nogami H, Maruyama S, Takii Y, Hayashida T, Takaishi H, Kitagawa Y, Oki E, Konishi T, Ishida F, Kudo SE, Ring JE, Protopopov A, Lyle S, Ling Y, Okuda S, Ishikawa T, Akazawa K, Takabe K, Wakai T.
    • Journal Title

      Oncotarget

      Volume: 24 Issue: 55 Pages: 93567-93579

    • DOI

      10.18632/oncotarget.20510

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10130
  • [Journal Article] Intravenous Carnitine Administration in Addition to Parenteral Nutrition with Lipid Emulsion may Decrease the Inflammatory Reaction in Postoperative Surgical Patients.2017

    • Author(s)
      KoyamaY, Moro K, Nakano M, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Hanyu T, Shimada Y, Jun Sakata J, Kameyama H, Kobayashi T, Wakai T.
    • Journal Title

      Journal of Clinical Medicine Research

      Volume: 9 Issue: 10 Pages: 831-837

    • DOI

      10.14740/jocmr3113w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Journal Article] Clinical significance of NQO1 expression in patients with advanced KRAS wild colorectal cancer2017

    • Author(s)
      Hitoshi Kameyama, Yuki Hirose, Yasunobu Matsuda, Masayuki Nagahashi, Hiroshi Ichikawa, You Sato, Saki Yamada, Shinnosuke Hotta, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
    • Journal Title

      Int J Clin Exp Pathol

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Journal Article] 肝細胞癌発癌過程におけるオートファジーを介した分子制御機構の解明2017

    • Author(s)
      坂田純、廣瀬雄己、齊藤哲也、小松雅明、若井俊文
    • Journal Title

      Medical Science Digest

      Volume: 43 Pages: 331-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10565
  • [Journal Article] Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer.2017

    • Author(s)
      Shimada Y, Yagi R, Kameyama H, Nagahashi M, Ichikawa H, Tajima Y, Okamura T, Nakano M, Nakano M, Sato Y, Matsuzawa T, Sakata J, Kobayashi T, Nogami H, Maruyama S, Takii Y, Kawasaki T, Homma KI, Izutsu H, Kodama K, Ring JE, Protopopov A, Lyle S, Okuda S, Akazawa K, Wakai T.
    • Journal Title

      Hum Pathol.

      Volume: 印刷中 Pages: 1-9

    • DOI

      10.1016/j.humpath.2017.02.004

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10130
  • [Journal Article] The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications2017

    • Author(s)
      Nakajima M, Nagahashi M, Rashid OM, Takabe K, Wakai T
    • Journal Title

      Tumour Biol.

      Volume: 39 Issue: 4 Pages: 101042-101042

    • DOI

      10.1177/1010428317699133

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-16K15610, KAKENHI-PROJECT-15H05676
  • [Journal Article] 癌と宿主におけるスフィンゴシン-1-リン酸の役割2017

    • Author(s)
      永橋昌幸、若井俊文
    • Journal Title

      BIO Clinica

      Volume: 32 Pages: 397-404

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Journal Article] Prognostic factors after imatinib secondary resistance: survival analysis in patients with unresectable and metastatic gastrointestinal stromal tumors.2016

    • Author(s)
      Kanda T, Ishikawa T, Kosugi S-I, Ueki K, Naito T, Wakai T, Hirota S.
    • Journal Title

      Int J Clin Oncol.

      Volume: 21 Issue: 2 Pages: 295-301

    • DOI

      10.1007/s10147-015-0903-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05166, KAKENHI-PROJECT-26461970
  • [Journal Article] The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases.2016

    • Author(s)
      Nagahashi M, Yuza K, Hirose Y, Nakajima M, Ramanathan R, Hait NC, Hylemon PB, Zhou H, Takabe K, Wakai T.
    • Journal Title

      J Lipid Res.

      Volume: 57 Issue: 9 Pages: 1636-43

    • DOI

      10.1194/jlr.r069286

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
  • [Journal Article] Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods.2016

    • Author(s)
      Nagahashi M, Yamada A, Miyazaki H, Allegood JC, Tsuchida J, Aoyagi T, Huang WC, Terracina KP, Adams BJ, Rashid OM, Milstien S, Wakai T, Spiegel S, Takabe K.
    • Journal Title

      J Mammary Gland Biol Neoplasia

      Volume: 21 Issue: 1-2 Pages: 9-17

    • DOI

      10.1007/s10911-016-9354-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19055, KAKENHI-PROJECT-16K19888
  • [Journal Article] Clinical significance of MED12 expression in colorectal cancer.2016

    • Author(s)
      Shimada Y, Tajima Y, Kameyama H, Yagi R, Okamura T, Hirose Y, Sakata J, Kobayashi T, Matsuda Y, Ajioka Y, Kosugi SI, Wakai T
    • Journal Title

      Int J Clin Exp Pathol.

      Volume: 9 Pages: 6937-44

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10130
  • [Journal Article] 脂質メディエーターを介した胆汁酸シグナル伝達系の役割2016

    • Author(s)
      永橋 昌幸, 大橋 拓, 滝沢 一泰, 坂田 純, 小林 隆, 若井 俊文
    • Journal Title

      胆道

      Volume: 30 Pages: 220-227

    • NAID

      130005157398

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Journal Article] Prognostic significance of NQO1 expression in esophageal squamous cell carcinoma after preoperative chemotherapy with cisplatin and 5-fluorouracil followed by curative esophagectomy2016

    • Author(s)
      Ichikawa H, Kosugi S, Hirose Y, Matsuda Y, Ishikawa T, Hanyu T, Usui K, Muneoka Y, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
    • Journal Title

      International Journal of Clinical and Experimental Pathology

      Volume: 9 Pages: 7393-7401

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461971
  • [Journal Article] Comparison of Number Versus Ratio of Positive Lymph Nodes in the Assessment of Lymph Node Status in Extrahepatic Cholangiocarcinoma2016

    • Author(s)
      Sakata J, Wakai T, Matsuda Y, Ohashi T, Hirose Y, Ichikawa H, Kobayashi T, Minagawa M, Kosugi S, Koyama Y, Akazawa K, Ajioka Y
    • Journal Title

      Ann Surg Oncol

      Volume: 23 Issue: 1 Pages: 225-234

    • DOI

      10.1245/s10434-015-4609-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Journal Article] Surgical and long-term outcomes following oesophagectomy in oesophageal cancer patients with comorbidity2016

    • Author(s)
      Ichikawa H, Kosugi SI, Kanda T, Yajima K, Ishikawa T, Hanyu T, Muneoka Y, Otani T, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
    • Journal Title

      International Journal of Surgery

      Volume: 36 Pages: 212-218

    • DOI

      10.1016/j.ijsu.2016.10.041

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Journal Article] Sphingosine-1-phosphate in the lymphatic fluid determined by novel methods.2016

    • Author(s)
      Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K
    • Journal Title

      Heliyon

      Volume: 2 Issue: 12 Pages: e00219-e00219

    • DOI

      10.1016/j.heliyon.2016.e00219

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K15610, KAKENHI-PROJECT-16K19055
  • [Journal Article] Low fat-containing elemental formula is effective for postoperative recovery and potentially useful for preventing chyle leak during postoperative early enteral nutrition after esophagectomy.2016

    • Author(s)
      Moro K, Koyama Y, Kosugi SI, Ishikawa T, Ichikawa H, Hanyu T, Miura K, Nagahashi M, Nakajima M, Tatsuda K, Tsuchida J, Toshikawa C, Ikarashi M, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Wakai T
    • Journal Title

      Clinical Nutrition

      Volume: 35 Issue: 6 Pages: 1423-1428

    • DOI

      10.1016/j.clnu.2016.03.018

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10047, KAKENHI-PROJECT-16K10491
  • [Journal Article] Tumor budding detection by immunohistochemical staining is not superior to hematoxylin eosin staining for predicting lymph node metastasis in pT1 colorectal cancer.2016

    • Author(s)
      Takuma Okamura
    • Journal Title

      Dis Colon Rectum

      Volume: 59 Issue: 5 Pages: 396-402

    • DOI

      10.1097/dcr.0000000000000567

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462007
  • [Journal Article] Prognostic significance of NQO1 expression in esophageal squamous cell carcinoma after preoperative chemotherapy with cisplatin and 5-fluorouracil followed by curative esophagectomy2016

    • Author(s)
      Ichikawa H, Kosugi S, Hirose Y, Matsuda Y, Ishikawa T, Hanyu T, Usui K, Muneoka Y, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
    • Journal Title

      International Journal of Clinical and Experimental Pathology

      Volume: 9 Pages: 7393-7401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Journal Article] Surgical resection of recurrent gastrointestinal stromal tumor after interruption of long-term nilotinib therapy.2016

    • Author(s)
      Sugase T, Takahashi T, Ishikawa T, Ichikawa H, Kanda T, Hirota S, Nakajima K, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Takiguchi S, Wakai T, Mori M, Doki Y.
    • Journal Title

      Surg Case Rep.

      Volume: 2 Issue: 1 Pages: 137-137

    • DOI

      10.1186/s40792-016-0266-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461970
  • [Journal Article] Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer.2016

    • Author(s)
      Moro K, Nagahashi M, Ramanathan R, Takabe K, Wakai T.
    • Journal Title

      World J Clin Cases.

      Volume: 4 Issue: 7 Pages: 155-64

    • DOI

      10.12998/wjcc.v4.i7.155

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471
  • [Journal Article] DNA damage response and sphingolipid signaling in liver diseases2016

    • Author(s)
      Nagahashi M, Matsuda Y, Moro K, Tsuchida J, Soma D, Hirose Y, Kobayashi T, Kosugi SI, Takabe K, Komatsu M, Wakai T
    • Journal Title

      Surg Today

      Volume: 印刷中 Issue: 9 Pages: 995-1005

    • DOI

      10.1007/s00595-015-1270-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
  • [Journal Article] Valproic acid overcomes transforming growth factor-β-mediated sorafenib resistance in hepatocellular carcinoma2014

    • Author(s)
      Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa, Yuki Hirose, Jun Sakata, Takashi Kobayashi, Shun Fujimaki, Masaaki Takamura, Satoshi Yamagiwa, Yutaka Aoyagi
    • Journal Title

      International Journal of Clinical & Experimental Pathology

      Volume: 7(4) Pages: 1299-1313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590962
  • [Journal Article] Valproic acid overcomes transforming growth factor-β-mediated sorafenib resistance in hepatocellular carcinoma.2014

    • Author(s)
      Matsuda Y, Wakai T, Kubota M, Osawa M, Hirose Y, Sakata J, Kobayashi T, Fujimaki S, Takamura M, Yamagiwa S, Aoyagi Y.
    • Journal Title

      Int J Clin Exp Pathol

      Volume: 7 (4) Pages: 1299-1313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590962
  • [Journal Article] Alteration of DNA damage resopnse in colorectal tumor progression2013

    • Author(s)
      Takabayashi H, Wakai T, Ajioka Y, Korita, Yamaguchi N
    • Journal Title

      Human Pathol

      Volume: 44 Issue: 6 Pages: 1038-1046

    • DOI

      10.1016/j.humpath.2012.09.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590391
  • [Journal Article] Risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts.2013

    • Author(s)
      Ohashi T, Wakai T, Kubota M, Matsuda Y, Arai Y, Ohyama T, Nakaya K, Okuyama N, Sakata J, Shirai Y, Ajioka Y
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 28 Issue: 2 Pages: 243-247

    • DOI

      10.1111/j.1440-1746.2012.07260.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592693, KAKENHI-PROJECT-24659773
  • [Journal Article] Assessment of lymph node status in gallbladder cancer: location, number, or ratio of positive nodes2013

    • Author(s)
      Shirai Y, Sakata J, Wakai T, Ohashi T, Ajioka Y, Hatakeyama K
    • Journal Title

      World Journal of Surgical Oncology

      Volume: 10 Issue: 1 Pages: 87-87

    • DOI

      10.1186/1477-7819-10-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Journal Article] Heavy alcohol intake is a risk factor for esophageal squamous cell carcinoma among middle-aged Chinese men : a case-control study and simulation2013

    • Author(s)
      Kumagai N, Akazawa K, Wakai T et al
    • Journal Title

      Molecular and Clinical Oncology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22406021
  • [Journal Article] Effects of rapamycin on granulation formation in response to centrally-doubled coiled stents as a tracheal substitute.2013

    • Author(s)
      Kubota M, Matsuda Y, Fujimaki S, Osawa M, Wakai T, Nakaya K
    • Journal Title

      J Pediatr Surg

      Volume: 48 Issue: 12 Pages: 2416-2424

    • DOI

      10.1016/j.jpedsurg.2013.08.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592693, KAKENHI-PROJECT-24659773
  • [Journal Article] pT_<2-3> (ss/se)胆嚢癌に対する外科切除2012

    • Author(s)
      若井俊文
    • Journal Title

      肝胆膵画像

      Volume: 14 Pages: 23-29

    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Assessment of lymph node status in gallbladder cancer : location, number, or ratio of positive nodes2012

    • Author(s)
      Shirai Y, Sakata J, Wakai T, Ohashi T, Ajioka Y, Hatakeyama K.
    • Journal Title

      World J Surg Oncol

      Volume: 10 Pages: 87-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Journal Article] Extended radical cholecystectomy for gallbladder cancer : long-term outcomes, indications and limitations2012

    • Author(s)
      Shirai Y, Sakata J, Wakai T, Ohashi T, Hatakeyama K.
    • Journal Title

      World J Gastroenterol

      Volume: 18 Pages: 4736-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Journal Article] Surgical Outcomes of Minor Hepatectomy for Locally Advanced Gallbladder Carcinoma2012

    • Author(s)
      Wakai T, Shirai Y, Sakata J, Tsuchiya Y, Nomura T, Hatakeyama K
    • Journal Title

      Hepatogastroenterology

      Volume: (掲載確定済み) Pages: 59-59

    • DOI

      10.5754/hge12097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Extended radical cholecystectomy for gallbladder cancer : long-term outcomes, indications, and limitations2012

    • Author(s)
      Shirai Y, Sakata J, Wakai T, Ohashi T, Hatakeyama K
    • Journal Title

      World Journal of Gastroenterology

      Volume: (掲載確定済み)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Regional lymphadenectomy for gallbladder cancer : rational extent, technical details, and patient outcomes2012

    • Author(s)
      Shirai Y, Wakai T, Sakata J, Hatakeyama K.
    • Journal Title

      World J Gastroenterol

      Volume: 18 Pages: 2775-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Journal Article] Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling.2012

    • Author(s)
      Fujimaki S, Matsuda Y, Wakai T, Sanpei A, Kubota M, Takamura M, Yamagiwa S, Yano M, Ohkoshi S, Aoyagi Y.
    • Journal Title

      Cancer lett

      Volume: 319 Issue: 1 Pages: 98-108

    • DOI

      10.1155/2013/597095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590962
  • [Journal Article] Full-thickness cholecystectomy with limited lymphadenectomy for gallbladder cancer2012

    • Author(s)
      Shirai Y, Sakata J, Wakai T, Hatakeyama K.
    • Journal Title

      Hepatogastroenterology

      Volume: 59 Pages: 1338-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Journal Article] Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2012

    • Author(s)
      Wakai T, Shirai Y, Sakata J, Korita PV, Ajioka Y, Hatakeyama K
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: 11 Issue: 3 Pages: 362-369

    • DOI

      10.1007/s00534-012-0539-1

    • NAID

      10031168232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590391, KAKENHI-PROJECT-24592021
  • [Journal Article] pT2-3(ss/se)胆嚢癌に対する外科切除2012

    • Author(s)
      若井俊文、白井良夫、坂田純、大橋拓、山口尚之、味岡洋一、畠山勝義
    • Journal Title

      肝胆膵画像

      Volume: 14 Pages: 23-29

    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] 胆嚢癌肝内進展様式とその診断2012

    • Author(s)
      若井俊文、坂田純、大橋拓、井上真、白井良夫、畠山勝義
    • Journal Title

      肝胆膵

      Volume: 64 Pages: 523-530

    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Regional lymphadenectomy for gallbladder cancer: rational extent, technical details, and patient outcomes2012

    • Author(s)
      Shirai Y, Wakai T, Sakata J, Hatakeyama K
    • Journal Title

      World J Gastroenterol

      Volume: 18(22) Issue: 22 Pages: 2775-83

    • DOI

      10.3748/wjg.v18.i22.2775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Journal Article] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011

    • Author(s)
      Wakai T, Shirai Y, Sakata J, Korita PV, Matsuda Y, Takamura M, Ohashi R, Nagahashi M, Ajioka Y, Hatakeyama K
    • Journal Title

      International Journal of Oncology

      Volume: 38 Pages: 1227-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590391
  • [Journal Article] Alcohol Consumption as a Risk Factor for Esophageal Adenocarcinoma in North China2011

    • Author(s)
      Chen J, Zhang N, Ling Y, Wakai T, He Y, Wei L, Wang S, Akazawa K
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 224 Issue: 1 Pages: 21-27

    • DOI

      10.1620/tjem.224.21

    • NAID

      10028233735

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22406021
  • [Journal Article] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011

    • Author(s)
      若井俊文、松田康伸, 他8名
    • Journal Title

      Int J Oncol

      Volume: 38 Issue: 5 Pages: 1227-1236

    • DOI

      10.3892/ijo.2011.959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590835, KAKENHI-PROJECT-21591768, KAKENHI-PROJECT-23590391
  • [Journal Article] 胆嚢癌2011

    • Author(s)
      若井俊文
    • Journal Title

      臨床外科

      Volume: 66 Pages: 1342-1347

    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011

    • Author(s)
      Wakai T, Shirai Y, Sakata J, Korita PV, Matsuda Y, Takamura M, Ohashi R, Nagahashi M, Ajioka Y, Hatakeyama K
    • Journal Title

      Int J Oncol

      Volume: 38(5) Pages: 1227-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Journal Article] 胆管癌根治切除後の胆管切離断端に遺残した上皮内癌における早期DNA損傷修復応答と局所再発との関連2010

    • Author(s)
      若井俊文, 他
    • Journal Title

      胆道

      Volume: 24 Pages: 667-674

    • NAID

      10030361447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Journal Article] Mode of hepatic spread from gallbladder cazcinoma : an immunohistochemical analysis of 42 hepatectomized specimens2010

    • Author(s)
      若井俊文, 白井良夫, ほか4名
    • Journal Title

      American Journal of Surgical Pathology

      Volume: Vol.34 Pages: 65-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Mode of hepatic spread from gallbladder carcinoma : an immunohistochemical analysis of 42 hepatectomized specimens2010

    • Author(s)
      若井俊文, 白井良夫, ほか4名
    • Journal Title

      American Journal of Surgical Pathology Vol.34

      Pages: 65-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] 胆管癌根治切除後の胆管切離断端に遺残した上皮内癌における早期DNA損傷修復応答と局所再発との関連2010

    • Author(s)
      若井俊文, 白井良夫, 坂田純, Korita V. Pavel, 味岡洋一, 畠山勝義
    • Journal Title

      胆道

      Volume: 24(5) Pages: 667-674

    • NAID

      10030361447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Journal Article] Mode of hepatic spread from gallbladder carcinoma American Journal of Surgical Pathology : an immunohistochemical analysis of 42 hepatectomized specimens2010

    • Author(s)
      Wakai T, Shirai Y, Sakata J, Nagahashi M, Ajioka Y, Hatakeyama K
    • Journal Title

      American Journal of Surgical Pathology

      Volume: 34 Pages: 65-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] 進行胆嚢癌における術式選択2010

    • Author(s)
      若井俊文, 白井良夫, ほか4名
    • Journal Title

      外科治療

      Volume: Vol.102 Pages: 232-238

    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Effect of the interaction between the amount and duration of alcohol consumption and tobacco smoking on the risk of esophageal cancer:A case-control study2010

    • Author(s)
      Chen J, Zhang N, Wakai T, Wei L, He Y, Kumagai N, Kitsu K, Wang S, Akazawa K
    • Journal Title

      Experimental and therapeutic medicine

      Volume: 1(6) Issue: 6 Pages: 991-997

    • DOI

      10.3892/etm.2010.152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22406021
  • [Journal Article] Number of positive lymph nodes independently determines the prognosis after resection in patients with gallbladder carcinoma2010

    • Author(s)
      Sakata J, Shirai Y, Wakai T, Ajioka Y, Hatakeyama K
    • Journal Title

      Annals of Surgical Oncology

      Volume: 17 Pages: 1831-1840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591769
  • [Journal Article] Tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 potentates the anchorage-independent growth of human hepatoma HepG2 cells2007

    • Author(s)
      Hokari, M, Matsuda, Y, Wakai, T, et. al.
    • Journal Title

      Life Science 81

      Pages: 336-345

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Journal Article] Tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 potentates the anchorage-independent growth of human hepatoma HepG2 cells.2007

    • Author(s)
      Hokari M, Matsuda Y, Wakai T, et. al.
    • Journal Title

      Life Science 81

      Pages: 336-345

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Journal Article] Long-term outcomes after hepatectomy for recurrences after prior local ablation for hepatocellular carcinoma.2007

    • Author(s)
      Sakata J, Shirai Y, Wakai T, et. al.
    • Journal Title

      European Journal of Surgical Oncology

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Journal Article] Anatomic resection independently improves long-term survival in patients with T1-T2 hepatocellular carcinoma.2007

    • Author(s)
      Wakai, T, Shirai, Y, Sakata, J, et. al.
    • Journal Title

      Annals of Surgical Oncology 14

      Pages: 1356-1365

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Journal Article] Anatomic resection independently improves long-term survival in patients with T1-T2 hepatocellular carcinoma.2007

    • Author(s)
      Wakai T, Shirai Y, Sakata J, et. al.
    • Journal Title

      Annals of Surgical Oncology 14

      Pages: 1356-1365

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Journal Article] Long-term outcomes after hepatectomy for recurrences after prior local ablation for hepatocellular carcinoma.2007

    • Author(s)
      Sakata, J, Shirai, Y, Wakai, T, et. al.
    • Journal Title

      European Journal of Surgical Oncology, PMID 17475439

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Journal Article] Long-term outcomes of hepatectomy vs percutaneous ablation for treatment of hepatocellular carcinoma 【less than or equal】 4 cm2006

    • Author(s)
      Wakai T, Shirai Y, Suda T, Yokoyama N, Sakata J, Cruz PV, Kawai H, Matsuda Y, Watanabe M, Aoyagi Y, Hatakeyama K
    • Journal Title

      World Journal of Gastroenterology 12・4

      Pages: 546-552

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Long-term outcomes of hepatectomy vs percutaneous ablation for treatment of hepatocellular carcinomas 【less than or equal】 4 cm.2006

    • Author(s)
      Wakai T, Shirai Y, Suda T, Yokoyama N, Sakata J, Cruz PV, Kawai H, Matsuda Y, Watanabe M, Aoyagi Y, Hatakeyama K.
    • Journal Title

      World Journal of Gastroenterology 12(4)

      Pages: 546-552

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Jaundice at presentation heralds advanced disease and poor prognosis in patients with ampullary carcinoma.2005

    • Author(s)
      Yokoyama N, Shirai Y, Wakai T, Nagakura S, Akazawa K, Hatakeyama K
    • Journal Title

      World Journal of Surgery 29・4

      Pages: 519-523

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Loss of carcinoembryonic antigen-related cell adhesion molecule 1 expression is an adverse prognostic factor in hepatocellular carcinoma.2005

    • Author(s)
      Cruz PV, Wakai T, Shirai Y, Yokoyama N, Hatakeyama K
    • Journal Title

      Cancer 104・2

      Pages: 354-360

    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Peroral cholangioscopy for non-invasive papillary cholangiocarcinoma with extensive superficial ductal spread.2005

    • Author(s)
      Wakai T, Shirai Y, Hatakeyama K.
    • Journal Title

      World Journal of Gastroenterology 11(41)

      Pages: 6554-6556

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Loss of carcinoembryonic antigen-related cell adhesion molecule 1 expression is an adverse prognostic factor in hepatocellular carcinoma.2005

    • Author(s)
      Cruz PV, Wakai t, Shirai Y, Yokoyama N, Hatakeyama K.
    • Journal Title

      Cancer 104(2)

      Pages: 354-360

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Jaundice at presentation heralds advanced disease and poor prognosis in patients with ampullary carcinoma.2005

    • Author(s)
      Yokoyama N, Shirai Y, Wakai T, Nagakura S, Akazawa K, Hatakeyama K.
    • Journal Title

      World Journal of Surgery 29(4)

      Pages: 519-523

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Impact of ductal resection margin status on long-term survival in patients undergoing resection for extrahepatic cholangiocarcinoma.2005

    • Author(s)
      Wakai T, Shirai Y, Moroda T, Yokoyama N, Hatakeyama K
    • Journal Title

      Cancer 103・6

      Pages: 1210-1216

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Impact of ductal resection margin status on long-term survival in patients undergoing resection for extrahepatic cholangiocarcinoma.2005

    • Author(s)
      Wakai T, Shirai Y, Moroda T, Yokoyama N, Hatakeyama K.
    • Journal Title

      Cancer 103(6)

      Pages: 1210-1216

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Loss of carcinoembryonic antigen-related cell adhesion molecule 1 expression is an adverse prognostic factor in hepatocellular carcinoma.2005

    • Author(s)
      Cruz PV, Wakai t, Shirai Y, Yokoyama N, Hatakeyama K
    • Journal Title

      Cancer 104・2

      Pages: 354-360

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Peroral cholangioscopy for non-invasive papillary cholangiocarcinoma with extensive superficial ductal spread.2005

    • Author(s)
      Wakai T, Shirai Y, Hatakeyama K
    • Journal Title

      World Journal of Gastroenterology 11・41

      Pages: 6554-6556

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Hepatitis viral status affects the pattern of intrahepatic recurrence after resection for hepatocellular carcinoma2003

    • Author(s)
      Toshifumi Wakai
    • Journal Title

      European Journal of Surgical Oncology 29

      Pages: 266-271

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591390
  • [Journal Article] Hepatitis viral status affects the pattern of intrahepatic recurrence after resection for hepatocellular carcinoma.2003

    • Author(s)
      T.Wakai
    • Journal Title

      European Journal of Surgical Oncology Vol.29

      Pages: 266-271

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591390
  • [Journal Article] Clinical significance of lymph node micrometastasis in ampullary carcinoma.

    • Author(s)
      Sakata E, Shirai Y, Yokoyama N, Wakai T, Sakata J, Hatakeyama K.
    • Journal Title

      World Journal of Surgery (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Journal Article] Clinical significance of lymph node micrometastasis in ampullary carcinoma

    • Author(s)
      Sakata E, Shirai Y, Yokoyama N, Wakai T, Sakata J, Hatakeyama K
    • Journal Title

      World Journal of Surgery (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591301
  • [Patent] 変異型ヒトDNAポリメラーゼε2021

    • Inventor(s)
      若井俊文、亀山仁史、永橋昌幸、島田能史、市川 寛
    • Industrial Property Rights Holder
      若井俊文、亀山仁史、永橋昌幸、島田能史、市川 寛
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2024
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Patent] SYSTEM, PROGRAM, AND METHOD FOR DETERMINING HYPERMUTATED TUMOR2021

    • Inventor(s)
      若井俊文、奥田修二郎、島田能史
    • Industrial Property Rights Holder
      若井俊文、奥田修二郎、島田能史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2024
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Patent] SYSTEM, PROGRAM, AND METHOD FOR DETERMINING HYPERMUTATED2021

    • Inventor(s)
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Holder
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Patent] 高頻度変異型癌の判別システム、プログラム及び方法2021

    • Inventor(s)
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Holder
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] 大腸癌肝転移Radiomics解析による遺伝子変異予測モデルの構築2024

    • Author(s)
      松本瑛生,中野雅人,山崎元彦,山井大介,宗岡悠介,田島陽介,島田能史,坂田 純,石川浩志、若井俊文
    • Organizer
      第79回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-22K08794
  • [Presentation] Correlation of mutational signature between whole genome sequencing and gene panel tests in colorectal cancer2023

    • Author(s)
      廣瀬雄己,島田能史,田島陽介,阿部 馨,松本瑛生,大関 瑛,土田純子,諸 和樹,宗岡悠介,市川 寛,竹内志穂,永橋昌幸,坂田 純,奥田修二郎,若井俊文
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08750
  • [Presentation] 切除可能胆嚢癌におけるHER2発現の評価2023

    • Author(s)
      坂田 純、滝沢一泰、三浦宏平、石川博補、廣瀬雄己、峠 弘治、安藤拓也、 水戸正人、三浦要平、長櫓宏規、斎藤征爾、安部 舜、宗岡悠介、加納陽介、 田島陽介、中野麻恵、市川 寛、島田能史、小林 隆、若井俊文
    • Organizer
      第31回日本消化器関連学会週間
    • Data Source
      KAKENHI-PROJECT-21K08770
  • [Presentation] 下部直腸癌の側方領域転移症例における壁外非連続性癌進展病巣の臨床的意義2023

    • Author(s)
      山井大介、島田能史、松本瑛生、阿部馨、田島陽介、中野麻恵、中野雅人、宗岡悠介、臼井賢司、石川博補、加納陽介、市川寛、滝沢一泰、坂田純、小林隆、野上仁、丸山聡、瀧井康公、奥田修二郎、若井俊文
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K08890
  • [Presentation] 遺伝子変異プロファイルからみた直腸癌の術前化学放射線療法における治療効果予測2023

    • Author(s)
      島田能史,田島陽介,中野麻恵,阿部 馨,山井大介,市川 寛,三浦宏平,坂田 純,小林 隆,若井俊文
    • Organizer
      第78回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-21K08703
  • [Presentation] 術前DCF療法後の食道切除例における原発巣の腫瘍遺残形式に関する検討2023

    • Author(s)
      宗岡 悠介, 市川 寛, 番場 竹生, 酒井 剛, 臼井 賢司, 加納 陽介, 島田 能史, 坂田 純, 、小林 隆, 中川 悟, 若井 俊文
    • Organizer
      JDDW2023
    • Data Source
      KAKENHI-PROJECT-22K08866
  • [Presentation] シンポジウム4(SY-04-2)固形癌におけるゲノム医療:腫瘍外科と融合したPrecision Cancer Medicine2023

    • Author(s)
      若井俊文,島田能史,中野麻恵,田島陽介,中野雅人,宗岡悠介,臼井賢司,加納陽介,市川 寛,石川 卓,諸 和樹,土田純子,安部 舜,安藤拓也,石川博補,廣瀬雄己,三浦宏平,滝沢一泰,坂田 純,小林 隆
    • Organizer
      第123回日本外科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] 大腸癌患者の全ゲノム解析と遺伝子パネル検査における変異シグネチャーの相関性2023

    • Author(s)
      廣瀬 雄己, 島田 能史, 田島 陽介, 安部 馨, 松本 瑛生, 大関 瑛, 土田 純子, 諸 和樹, 宗岡 悠介, 市川 寛, 竹内 志穂, 永橋 昌幸, 坂田 純, 奥田 修二郎, 若井 俊文
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] 大腸癌における細菌叢と臨床病理学的因子および予後との関連2023

    • Author(s)
      田島 陽介, 島田 能史, 中野 麻恵, 中野 雅人, 山井 大介, 阿部 馨, 松本 瑛生, 大関 瑛, 宗岡 悠介, 廣瀬 雄己, 臼井 賢司, 石川 博補, 加納 陽介, 三浦 宏平, 市川 寛, 滝沢 一泰, 小林 隆, 坂田 純, 奥田 修二郎, 若井 俊文
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] 指導医養成講座1 胆道癌における遺伝子異常2023

    • Author(s)
      若井俊文
    • Organizer
      第59回日本胆道学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] 術前DCF療法後の食道切除例における再発予後因子の検討2022

    • Author(s)
      宗岡悠介,市川 寛,番場 竹生,臼井賢司,加納陽介,石川 卓,島田能史,坂田 純,小林 隆,中川 悟,若井俊文
    • Organizer
      JDDW2022
    • Data Source
      KAKENHI-PROJECT-22K08866
  • [Presentation] 地域連携を利用した直腸癌の集学的治療への取り組み2022

    • Author(s)
      島田 能史,松本 瑛生,中野 麻恵,中野 雅人,市川 寛,羽入 隆晃,滝沢 一泰,坂田 純,小林 隆,若井 俊文
    • Organizer
      第77回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-21K08703
  • [Presentation] 臨床的側方リンパ節転移の臨床的意義 -病理学的側方リンパ節転移との比較から-2022

    • Author(s)
      山井大介、島田能史、中野雅人、松本瑛生、中野麻恵、滝沢一泰、坂田純、小林隆、瀧井康公、若井俊文
    • Organizer
      第77回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-22K08890
  • [Presentation] ヒトの大腸癌および大腸粘膜に定着した細菌を同定する手法の検討2022

    • Author(s)
      田島陽介、廣純一郎、松岡 宏、花井 恒一、島田能史、奥田修二郎、若井俊文、須田康一
    • Organizer
      第30回日本消化器関連学会週間(JDDW2022)
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] Tumor mutational burden-High大腸癌を予測する人工知能の開発2022

    • Author(s)
      島田能史、奥田修二郎、中野麻恵、松本瑛生、 田島陽介、中野雅人、石川博補、臼井賢司、加納陽介、三浦宏平、市川寛、羽入隆晃、滝沢一泰、石川卓、坂田純、小林隆、野上仁、丸山聡、瀧井康公、若井俊文
    • Organizer
      第122回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] Clinical Significance of the Expression of Phosphorylated Sphingosine Kinase1 in Pancreatic cancer2022

    • Author(s)
      Kazuyasu Takizawa, Hiroki Nagaro, Jun Sakata, Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Takashi Kobayashi, Toshifumi Wakai
    • Organizer
      The 17th Annual Academic Surgical Congress (ASC)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09099
  • [Presentation] 下部直腸癌の側方領域おける壁外非連続性癌進展病巣の臨床的意義2022

    • Author(s)
      山井大介、島田能史、松本瑛生、田島陽介、中野麻恵、中野雅人、宗岡悠介、加納陽介、石川博補、三浦宏平、市川寛、羽入隆晃、滝沢一泰、石川卓、坂田純、小林隆、野上仁、丸山聡、瀧井康公、若井俊文
    • Organizer
      第20回日本消化器外科学会大会
    • Data Source
      KAKENHI-PROJECT-22K08890
  • [Presentation] 肝内胆管癌におけるゲノム医療:腫瘍外科と融合したPrecision Cancer Medicineへの取り組み2022

    • Author(s)
      若井俊文
    • Organizer
      第30回日本消化器関連学会週間(JDDW2022)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer 大腸癌における宿主の遺伝子変異と腫瘍内細菌叢のプロファイリング2021

    • Author(s)
      Toshifumi Wakai, Shujiro Okuda, Yoshifumi Shimada, Yosuke Tajima, Yuki Hirose, Hiroshi Ichikawa, Yiwei Ling, Nobuaki Miura, Mika Sugai, Yu Watanabe, Shiho Takeuchi, Jun Sakata
    • Organizer
      The 32nd Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22651
  • [Presentation] 直腸癌の化学放射線療法における治療効果予測-がん遺伝子パネル検査による遺伝子変異プロファイリングから-2021

    • Author(s)
      島田能史,小柳英人,松本瑛生,阿部馨,田中花菜,田島陽介,中野麻恵,中野雅人,諸和樹,須藤翔,加納陽介,三浦宏平,市川寛,羽入隆晃,滝沢一泰,永橋昌幸,坂田純,小林隆,小杉伸一,若井俊文
    • Organizer
      第121回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21K08703
  • [Presentation] 肥満状態下の乳癌転移におけるスフィンゴシン-1-リン酸の役割2021

    • Author(s)
      永橋 昌幸,土田 純子,諸 和樹,長谷川 遙,小幡 泰生,遠藤 麻巳子, 利川 千絵,五十嵐 麻由子,小山 諭,高部 和明,若井 俊文
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03714
  • [Presentation] 固形癌におけるゲノム医療:腫瘍外科と融合したPrecision Cancer Medicineへの取り組み2021

    • Author(s)
      若井俊文
    • Organizer
      第30回大腸Ⅱc研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] 直腸癌に対する術前化学放射線療法後の直腸温存治療の検討2021

    • Author(s)
      島田能史,松本瑛生,小柳英人,平井裕美子,荒引みちる,田中花菜,阿部馨,田島陽介,中野麻恵,中野雅人,廣瀬雄己,加納陽介,三浦宏平,市川寛,羽入隆晃,滝沢一泰,石川卓,坂田純,小林隆,若井俊文
    • Organizer
      JDDW2021
    • Data Source
      KAKENHI-PROJECT-21K08703
  • [Presentation] NES-06-1 外科学再興シンポジウム06「ゲノム解析による外科治療の進歩」 固形癌におけるゲノム解析に基づく外科治療の現況と将来展望2021

    • Author(s)
      若井俊文
    • Organizer
      第121回日本外科学会定期学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] 卵巣癌直腸浸潤における直腸間膜リンパ節転移は術後の血行性肝転移を予測する2021

    • Author(s)
      田中 花菜, 島田 能史, 中野 麻恵, 中野 雅人, 市川 寛, 羽入 隆晃, 滝沢 一泰, 坂田 純, 小林 隆, 若井 俊文
    • Organizer
      第76回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09116
  • [Presentation] Gene panel testing as a clinical application for detecting HER2 alterations in gastric cancer2020

    • Author(s)
      Hiroshi Ichikawa, Kenji Usui, Yoshifumi Shimada, Yusuke Muneoka, Takaaki Hanyu, Yosuke Kano, Takashi Ishikawa, Kohei Miura, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Hiroshi Yabusaki, Satoru Nakagawa, Hitoshi Kameyama, Shujiro Okuda, Toshifumi Wakai
    • Organizer
      15th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09117
  • [Presentation] 乳癌微小環境における組織間質液中のスフィンゴリン脂質定量の試み2020

    • Author(s)
      永橋昌幸,土田純子,諸 和樹,遠藤麻巳子,庭野稔之,山浦久美子,利川千絵,長谷川美樹,五十嵐麻由子,中島真人,小山 諭,高部和明,若井俊文
    • Organizer
      第28回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Presentation] 慢性炎症による癌の増殖・転移を促進する脂質メディエーター分子機構2020

    • Author(s)
      永橋 昌幸,土田 純子,油座 築,諸 和樹,根本 万里子,廣瀬 雄己,利川 千絵,五十嵐 麻由子,三浦 宏平,市川 寛,羽入 隆晃,滝沢 一泰,中島 真人,島田 能史,小林 隆,坂田 純,石川 卓,亀山 仁史,若井 俊文
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19H03714
  • [Presentation] Association between estrogen receptor status and plasma S1P levels in breast cancer patients2020

    • Author(s)
      Masayuki Nagahashi, Junko Tsuchida, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
    • Organizer
      The 15th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Presentation] Involvement of sphingosine-1-phosphate in tumor immune microenvironment of breast cancer patients2020

    • Author(s)
      Junko Tsuchida, Masayuki Nagahashi, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
    • Organizer
      The 15th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03714
  • [Presentation] 卵巣癌直腸浸潤における直腸間膜リンパ節転移は血行性肝転移の危険因子である2020

    • Author(s)
      中野雅人、島田能史、荒引みちる、田中花菜、阿部 馨、小柳英人、田島陽介、中野麻恵、廣瀬雄己、堅田朋大、加納陽介、三浦宏平、市川 寛、羽入隆晃、滝沢一泰、永橋昌幸、坂田 純、小林 隆、亀山仁史、若井俊文
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19K09116
  • [Presentation] 次世代シークエンサーを用いた遺伝子検査とゲノム解析データベース構築2019

    • Author(s)
      永橋昌幸、若井俊文、島田能史、市川寛、羽入隆晃、滝沢一泰、石川卓、坂田純、小林隆、亀山仁史、竹内志穂、奥田修二郎
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] リン酸化抗体を用いた免疫組織化学による消化器癌の脂質メディエーター解析研究2019

    • Author(s)
      永橋 昌幸, 油座 築, 廣瀬 雄己, 市川 寛, 羽入 隆晃, 島田 能史, 小林 隆, 坂田 純, 亀山 仁史, 若井 俊文
    • Organizer
      第74回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] Genomic alteration spectrum and future direction of targeted therapy for gastric cancer2019

    • Author(s)
      Hiroshi Ichikawa, Hiroshi Yabusaki, Takaaki Hanyu, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      第74回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10580
  • [Presentation] Mutational signatures and clinicopathological relationship extracted from clinical sequence data of 201 cases with colorectal cancer.2019

    • Author(s)
      Takeuchi, S., Ling, Y., Watanabe, Y., Shimada, Y., Wakai, T., Okuda, S.
    • Organizer
      ASHG2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] 大腸癌のPrecision medicineの現状と展望 大腸癌診療における遺伝子パネル検査の可能性2019

    • Author(s)
      島田 能史, 永橋 昌幸, 市川 寛, 田島 陽介, 中野 雅人, 阿部 馨, 田中 花菜, 小柳 英人, 諸 和樹, 滝沢 一泰, 羽入 隆晃, 廣瀬 雄己, 三浦 宏平, 小林 隆, 坂田 純, 亀山 仁史, 野上 仁, 丸山 聡, 瀧井 康公, 若井 俊文
    • Organizer
      第74回日本大腸肛門病学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] Macrophage migration inhibitory factor expression predicts clinical outcomes in patients with resected pancreatic ductal adenocarcinoma2019

    • Author(s)
      (2)Kabuto Takano, Jun Sakata, Yuki Hirose, Kohei Miura, Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Hitoshi Kameyama, Takashi Kobayashi, Toshifumi Wakai
    • Organizer
      The 7th Biennial Congress of the Asian-Pacific-Hepato-Pancreato-Biliary Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10690
  • [Presentation] NQO1 Expression Predicts OS and Response to Preoperative Chemotherapy in Colorectal Liver Metastasis2019

    • Author(s)
      廣瀬雄己、坂田純、小林隆、滝沢一泰、三浦宏平、堅田朋大、永橋昌幸、島田能史、市川寛、亀山仁史、若井俊文
    • Organizer
      14th ANNUAL ACADEMIC SURGICAL CONGRESS
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10663
  • [Presentation] Macrophage migration inhibitory factor expression predicts clinical outcomes in patients with resected pancreatic ductal adenocarcinoma2019

    • Author(s)
      Kabuto Takano, Jun Sakata, Yuki Hirose, Kohei Miura, Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Hitoshi Kameyama, Takashi Kobayashi, Toshifumi Wakai
    • Organizer
      The 7th Biennial Congress of the Asian-Pacific-Hepato-Pancreato-Biliary Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10690
  • [Presentation] 固形癌における包括的ゲノム解析に基づくPrecision Medicine2019

    • Author(s)
      若井俊文、島田能史、永橋昌幸、市川寛、油座築、根本万里子、中野麻恵、廣瀬雄己、滝沢一泰、坂田純、亀山仁史、小林隆、棗田学、吉原弘祐、奥田修二郎
    • Organizer
      第57回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] 日本人ゲノム安定型胃癌の特徴2019

    • Author(s)
      酒井 剛,市川 寛,羽入 隆晃,石川 卓,臼井 賢司,根本 万理子,廣瀬 雄己,堅田 朋大,三浦 宏平,田島 陽介,滝沢 一泰,中野 雅人,島田 能史,永橋 昌幸,坂田 純,小林 隆,亀山 仁史,若井 俊文
    • Organizer
      第27回日本消化器関連学会週間
    • Data Source
      KAKENHI-PROJECT-17K10580
  • [Presentation] リン酸化抗体を用いた免疫組織化学による消化器癌の脂質メディエーター解析研究2019

    • Author(s)
      永橋 昌幸,油座 築,廣瀬 雄己,市川 寛,羽入 隆晃,島田 能史,小林 隆,坂田 純,亀山 仁史,若井 俊文
    • Organizer
      第74回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10692
  • [Presentation] Genomic alteration spectrum and future direction of targeted therapy for gastric cancer2019

    • Author(s)
      Hiroshi Ichikawa, Hiroshi Yabusaki, Takaaki Hanyu, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      第74回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09117
  • [Presentation] 婦人科悪性疾患に対する消化器外科介入症例の検討2019

    • Author(s)
      亀山 仁史, 島田 能史, 阿部 馨, 小柳 英人, 中野 麻恵, 中野 雅人, 市川 寛, 羽入 隆晃, 滝沢 一泰, 永橋 昌幸, 坂田 純, 小林 隆, 西川 伸道, 榎本 隆之, 若井 俊文
    • Organizer
      第41回日本癌局所療法研究会
    • Data Source
      KAKENHI-PROJECT-19K09116
  • [Presentation] Genomic alteration spectrum and future direction of targeted therapy for gastric cancer2019

    • Author(s)
      Hiroshi Ichikawa, Hiroshi Yabusaki, Takaaki Hanyu, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      第74回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-18K08698
  • [Presentation] Defective Homologous Recombination in Platinum-based Chemotherapy for Gastric Cancer2019

    • Author(s)
      T. Katada, H. Ichikawa, Y. Hirose, M. Nagahashi, Y. Shimada, T. Hanyu, T. Ishikawa, Y. Kano, Y. Muneoka, J. Sakata, T. Kobayashi, H. Kameyama, T. Wakai
    • Organizer
      14th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08698
  • [Presentation] Sphingosine-1-phospate Signaling Regulates Drug Resistance Mediated by Glutathione2019

    • Author(s)
      Nagahashi M, Tsuchida J, Moro K, Ikarashi M, Nakajima M, Abe M, Saito T, Komatsu M, Soga T, Takabe K, Sakimura K, Wakai T
    • Organizer
      The 14th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Presentation] 切除不能大腸癌に対するConversion Surgeryの現状 切除不能大腸癌のConversion Surgeryにおける遺伝子パネル検査の意義2019

    • Author(s)
      島田 能史, 中野 雅人, 市川 寛, 永橋 昌幸, 羽入 隆晃, 小林 隆, 坂田 純, 亀山 仁史, 瀧井 康公, 若井 俊文
    • Organizer
      第74回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] Tumor location and alteration spectrum of actionable genes in gastroesophageal cancer2019

    • Author(s)
      Hiroshi Ichikawa, Yoshifumi Shimada, Masayuki Nagahashi, Takaaki Hanyu, Yosuke Kano, Yusuke Muneoka, Takashi Ishikawa, Yuki Hirose, Kohei Miura, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hiroshi Yabusaki, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      第57回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10580
  • [Presentation] 大腸癌Hypermutationの臨床病理学的特徴(Clinicopathological features of hypermutation in colorectal cancer)2019

    • Author(s)
      島田 能史, 田島 陽介, 小柳 英人, 永橋 昌幸, 市川 寛, 中野 麻恵, 中野 雅人, 諸 和樹, 坂田 純, 小林 隆, 亀山 仁史, 奥田 修二郎, 若井 俊文
    • Organizer
      第78回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] Pathogenic germline BRCA1/2 mutations and familial predisposition to gastric cancer2018

    • Author(s)
      Ichikawa H,Nagahashi M,Shimada Y,Hanyu T,Ishikawa T,Muneoka Y,Kano Y,Takizawa K,Miura K,Hirose Y,Yuza K,Tsuchida J,Sakata J,Kobayashi T,Kameyama H,Yabusaki H,Nakagawa S,Okuda S,Takabe K,Wakai T
    • Organizer
      2018 American Society of Clinical Oncology Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10580
  • [Presentation] 大腸癌肝転移に対する術前化学療法 NQO1発現を用いた治療効果予測の可能性2018

    • Author(s)
      相馬大輝、坂田純、小林隆、滝沢一泰、三浦宏平、堅田朋大、石川博補、廣瀬雄己、峠弘治、油座築、安藤拓也、田島陽介、市川寛、羽入隆晃、永橋昌幸、中島真人、島田能史、亀山仁史、若井俊文
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K10663
  • [Presentation] High levels of sphingolipids in human pancreatic cancer2018

    • Author(s)
      K. Yuza, M. Nagahashi, Y. Hirose, M. Nakajima, K. Miura, H. Ichikawa, Y. Shimada, J. Sakata, H. Kameyama, T. Kobayashi, K. Takabe, T. Wakai
    • Organizer
      The 13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] Sphingosine-1-phosphate produced by sphingosine kinase type 1 and type 2 works differently in pancreatic cancer2018

    • Author(s)
      M. Nakajima, K. Yuza, J. Tsuchida, Y. Hirose, K. Miura, H. Ichikawa, Y. Shimada, T. Kobayashi, J. Sakata, H. Kameyama, M. Abe, K. Sakimura, T. Wakai, M. Nagahashi
    • Organizer
      The 13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] High Expression of Sphingosine Kinase 1 in Colitis-Associated Cancer2018

    • Author(s)
      Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Ichikawa H, Sakata J, Kobayashi T, Takabe K, Wakai T
    • Organizer
      13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] 胆管生検で採取した正常上皮・炎症上皮・癌組織におけるDNA二本鎖切断のマーカーであるγH2AX発現の検討2018

    • Author(s)
      廣瀬 雄己, 坂田 純, 安藤 拓也, 油座 築, 堅田 朋大, 三浦 宏平, 滝沢 一泰, 永橋 昌幸, 小林 隆, 若井 俊文
    • Organizer
      日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10691
  • [Presentation] ヒト胆道癌組織における脂質メディエーターS1Pの発現とその意義2018

    • Author(s)
      廣瀬雄己, 永橋昌幸, 油座築, 安藤拓也, 相馬大輝, 諸和樹, 峠弘治, 石川博補, 堅田朋大, 三浦宏平, 市川寛, 滝沢一泰, 中島真人, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
    • Organizer
      第118回日本外科学会定期学術集会(東京都)
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] Chemotherapeutic biomarkers for predicting tumor response in patients with gastric cancer: Defective homologous2018

    • Author(s)
      Ichikawa H,Hanyu T,Ishikawa T,Katada T,Shimada Y,Sakata J,Kobayashi T,Nakagawa S,Kameyama H,Wakai T
    • Organizer
      第73回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10580
  • [Presentation] シンポジウム 5 ゲノム医療推進に向けた取り組みの課題と展望 当科におけるゲノム医療推進に向けた取組み2018

    • Author(s)
      永橋 昌幸,土田 純子,遠藤 麻巳子,諸 和樹,庭野 稔之,山浦 久美子,利川 千絵,長谷川 美樹,五十嵐 麻由子,中島 真人,小山 諭,神林 智寿子,金子 耕司,佐藤 信昭,若井 俊文
    • Organizer
      第26回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Presentation] The Significance of Phospho-Sphingosine Kinase 1 in the Lymphatic Spread of Esophageal Carcinoma2018

    • Author(s)
      Ichikawa H, Nagahashi M, Nemoto M, Hanyu T, Ishikawa T, Kano Y, Muneoka Hirose Y, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Kazuaki T, Wakai T
    • Organizer
      13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] High Levels of Sphingolipids in Human Pancreatic Cancer2018

    • Author(s)
      Yuza K, Nagahashi M, Hirose Y, Nakajima M, Miura K, Ichikawa H, Shimada Y, Sakata J, Kameyama H, Kobayashi T, Takabe K, Wakai T
    • Organizer
      13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] 食道扁平上皮癌リンパ行性進展におけるphospho-sphingosine kinase 1発現の意義2018

    • Author(s)
      市川 寛,根本 万理子,石川 卓,羽入 隆晃,角田 知行,須藤 翔,島田 能史,永橋 昌幸,坂田 純,小林 隆,亀山 仁史,若井 俊文
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] 潰瘍性大腸炎関連大腸癌診断における脂質メディエーター(S1P)解析の有用性2018

    • Author(s)
      亀山仁史,永橋昌幸,油座 築,田島陽介,羽入隆晃,中野雅人,中島真人,島田能史,坂田 純,若井俊文
    • Organizer
      第73回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] 大腸癌肝転移におけるNQO1発現が肝切除術後の遠隔成績に与える影響2018

    • Author(s)
      廣瀬雄己、坂田純、安藤拓也、油座築、峠弘治、堅田朋大、三浦宏平、滝沢一泰、小林隆、永橋昌幸、島田能史、亀山仁史、若井俊文
    • Organizer
      第26回日本消化器関連週間(第17回日本消化器外科学会大会)
    • Data Source
      KAKENHI-PROJECT-17K10663
  • [Presentation] Dysregulation of Sphingolipids in Human Hepatocellular Carcinoma2018

    • Author(s)
      Miura K, Nagahashi M, Hirose Y, Kobayashi T, Sakata J, Kameyama H, Shimada Y, Ichikawa H, Takabe K, Wakai T
    • Organizer
      13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] Sphingosine Kinase Type 1 and Type 2 Works Differently in Pancreatic Cancer2018

    • Author(s)
      Nakajima M, Yuza K, Tsuchida J, Hirose Y, Miura K, Ichikawa H, Shimada Y, Kobayashi T, Sakata J, Kameyama H, Abe M, Sakimura K, Wakai T, Nagahashi M
    • Organizer
      13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] Dysregulation of Sphingolipids in Human Hepatocellular Carcinoma2018

    • Author(s)
      K. Miura, M. Nagahashi, Y. Hirose, T. Kobayashi, J. Sakata, H. Kameyama, Y. Shimada, H. Ichikawa, K. Takabe, T. Wakai
    • Organizer
      The 13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] High Expression of Sphingosine Kinase 1 in Colitis-Associated Cancer2018

    • Author(s)
      Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Ichikawa H, Sakata J, Kobayashi T, Takabe K, Wakai T
    • Organizer
      14th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] Human Biliary Tract Cancer Contains High Levels of S1P2018

    • Author(s)
      Hirose Y, Nagahashi M, Yuza K, Miura K, Sakata J, Kobayashi T, Ichikawa H, Shimada Y, Kameyama H, Takabe K, Wakai T
    • Organizer
      13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] 潰瘍性大腸炎に合併した大腸癌(colitic cancer)におけるリン酸化スフィンゴシンキナーゼ1高発現の意義2018

    • Author(s)
      油座 築、永橋昌幸、島田能史、中野麻恵、田島陽介、亀山仁史、中島真人、市川 寛、坂田 純、小林 隆、高部和明、若井俊文
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] 胆管生検組織標本の良・悪性判定にγH2AX発現が有用である2018

    • Author(s)
      石川 博補, 廣瀬 雄己, 永橋 昌幸, 坂田 純, 相馬 大輝, 安藤 拓也, 油座 築, 堅田 朋大, 三浦 宏平, 滝沢 一泰, 小林 隆, 田島 陽介, 市川 寛, 羽入 隆晃, 島田 能史, 亀山 仁史, 若井 俊文
    • Organizer
      日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K10691
  • [Presentation] 肥満が引き起こす慢性炎症による乳癌の転移促進と脂質メディエーターの役割2018

    • Author(s)
      永橋 昌幸,土田 純子,油座 築,中島 真人,高部 和明,若井 俊文
    • Organizer
      第25回外科侵襲とサイトカイン研究会
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Presentation] 肝細胞癌患者における脂質メディエーター・スフィンゴシン-1-リン酸及びセラミドの定量とその意義2018

    • Author(s)
      永橋 昌幸, 廣瀬 雄己, 三浦 宏平, 油座 築, 相馬 大輝, 安藤 拓也, 峠 弘治, 石川 博輔, 堅田 朋大, 坂田 純, 小林 隆, 中島 真人, 羽入 隆晃, 市川 寛, 石川 卓, 島田 能史, 亀山 仁史, 高部 和明, 若井 俊文
    • Organizer
      日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-18K08672
  • [Presentation] がんプレシジョンメディシン実現に向けたバイオインフォマティクス:遺伝子変異と治療薬の知識ベース2018

    • Author(s)
      竹内志穂、凌一葦、渡邉由、若井俊文、奥田修二郎
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] The Significance of Phospho-Sphingosine Kinase 1 in the Lymphatic Spread of Esophageal Carcinoma2018

    • Author(s)
      Hiroshi Ichikawa, Masayuki Nagahashi, Mariko Nemoto, Takaaki Hanyu, Takashi Ishikawa, Yosuke Kano, Yusuke Muneoka, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10491
  • [Presentation] Human biliary tract cancer contains high levels of S1P2018

    • Author(s)
      Yuki Hirose, Masayuki Nagahashi, Kizuki Yuza, Kohei Miura, Jun Sakata, Takashi Kobayashi, Hiroshi Ichikawa, Yoshifumi Shimada, Hitoshi Kameyama, Kazuaki Takabe, Toshifumi Wakai
    • Organizer
      The 13th Annual Academic Surgical Congress (Florida, USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] Human biliary tract cancer contains high levels of S1P2018

    • Author(s)
      Y. Hirose, M. Nagahashi, K. Yuza, K. Miura, J. Sakata, T. Kobayashi, H. Ichikawa, Y. Shimada, H. Kameyama, K. Takabe, T. Wakai
    • Organizer
      The 13th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] リン酸化スフィンゴシンキナーゼ1の発言と胃癌の進行についての関連2018

    • Author(s)
      羽入隆晃, 永橋昌幸, 市川寛, 石川卓, 角田知行, 須藤翔, 根本万理子, 小杉伸一, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-15K10087
  • [Presentation] Tumor mutation burden in triple negative breast cancer patients in Japan2018

    • Author(s)
      Nagahashi M, Ling Y, Hayashida T, Kitagawa Y, Futamura M, Yoshida K, Kuwayama T, Nakamura S, Toshikawa C, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Miyoshi Y, Tsuchida J, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Takabe K, Okuda S, Wakai T
    • Organizer
      2018 American Society of Clinical Oncology Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Presentation] 胃癌における相同組換え修復機構の破綻と予後2018

    • Author(s)
      市川 寛,羽入 隆晃,石川 卓,加納 陽介,宗岡 悠介,堅田 朋大,島田 能史,永橋 昌幸,坂田 純,小林 隆,亀山 仁史,中川 悟,若井 俊文
    • Organizer
      第26回日本消化器関連学会週間JDDW2018
    • Data Source
      KAKENHI-PROJECT-17K10580
  • [Presentation] 胃癌におけるDNAミスマッチ修復遺伝子変異とアクチビン2型受容体遺伝子変異の検討2017

    • Author(s)
      油座 築,永橋 昌幸,市川 寛,島田 能史,若井 俊文
    • Organizer
      第5回 新潟大学医学系基礎-臨床研究交流会
    • Data Source
      KAKENHI-PROJECT-17K10579
  • [Presentation] Association of activin type II receptor mutation with microsatellite instability in gastric cancer.2017

    • Author(s)
      Yuza K,Nagahashi M,Ichikawa H,Nakajima M,Hanyu T,Ishikawa T,Shimada Y,Sakata J,Kameyama H,Kobayashi T,Nakagawa S,Sato N,Honma K,Kawasaki T,Okuda S,Takabe K,Wakai T
    • Organizer
      2017 ASCO Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10579
  • [Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of gastric cancer2017

    • Author(s)
      Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      The 12th Annual Academic Surgical Congress
    • Place of Presentation
      Las Vegas(USA)
    • Year and Date
      2017-02-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10087
  • [Presentation] 膵がんにおけるCRISPR/Cas9を用いたスフィンゴシン-1-リン酸産生酵素の機能解析2017

    • Author(s)
      中島 真人,永橋 昌幸,三浦 要平,安藤 拓也,油座 築,土田 純子,田島 陽介,坂田 純,小林 隆,亀山 仁史,阿部 学,崎村 建司,若井 俊文
    • Organizer
      第117回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of gastric cancer2017

    • Author(s)
      Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      The 12th Annual Academic Surgical Congress(国際学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10087
  • [Presentation] Function Analysis of Sphingosine-1-Phosphate Produced by Sphingosine Kinases in Pancreatic Cancer Progression.2017

    • Author(s)
      Masato Nakajima,Masayuki Nagahashi,Junko Tsuchida,Hiroshi Ichikawa,Yoshifumi Shimada,Toshifumi Wakai
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] 膵癌細胞におけるスフィンゴシン-1-リン酸産生酵素の働きとその代謝動態制御の解析2017

    • Author(s)
      中島 真人,永橋 昌幸,三浦 要平,安藤 拓也,油座 築,土田 純子,田島 陽介,坂田 純,小林 隆,亀山 仁史,阿部 学,﨑村 建司,曽我 朋義,若井 俊文
    • Organizer
      日本外科代謝栄養学会第54回学術集会
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] 胃癌におけるマイクロサテライト不安定性とアクチビン受容体遺伝子変異の検討2017

    • Author(s)
      油座 築,永橋 昌幸,市川 寛,羽入 隆晃,石川 卓,中島 真人,島田 能史,坂田 純,亀山 仁史,小林 隆,中川 悟,井筒 浩,兒玉 啓輔,高部 和明,若井 俊文
    • Organizer
      第117回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K10579
  • [Presentation] Roles of Sphingosine-1-Phosphate Produced by Sphingosine Kinases in Pancreatic Cancer Progression2017

    • Author(s)
      Nakajima M, Miura Y, Ando T, Yuza K, Tsuchida J, Tajima Y, Abe M, Sakimura K, Wakai T, Nagahashi M
    • Organizer
      The 12th Annual Academic Surgical Congress
    • Place of Presentation
      Las Vegas, USA
    • Year and Date
      2017-02-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of human gastric cancer2017

    • Author(s)
      Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
    • Organizer
      第89回日本胃癌学会総会
    • Data Source
      KAKENHI-PROJECT-15K10087
  • [Presentation] Validity of adding intravenous carnitine to parenteral nutrition with lipid emulsion for deceasing inflammatory reaction of postoperative surgical patients.2017

    • Author(s)
      Koyama Y, Moro K, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Shimada Y, Kameyama H, Kobayashi T, Wakai T
    • Organizer
      39th ESPEN
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Presentation] Activin type II receptor as an affordable surrogate to identify microsatellite instability2017

    • Author(s)
      Yuza K,Nagahashi M,Ichikawa H,Hanyu T,Ishikawa T,Shimada Y,Sakata J,Kameyama H,Kobayashi T,Izutsu H,Kodama K,Takabe K,Wakai T
    • Organizer
      12th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10579
  • [Presentation] 膵癌切除例における Macrophage migration inhibitory factorの発現と治療成績2017

    • Author(s)
      高野可赴、滝沢一泰、坂田純、小林隆、若井俊文、安藤拓也、油座築、峠弘治、石川博補、三浦宏平、大橋拓、市川寛、羽入隆晃、永橋昌幸、石川卓、亀山仁史
    • Organizer
      第117回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K10690
  • [Presentation] Symposia S1:New trends for studying cancer invasion and metastasis The role of sphingosine-1-phosphate in tumor microenvironment and metastasis2017

    • Author(s)
      Nagahashi M, Tsuchida J, Nakajima M, Takabe K, Wakai T
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] Association between Activin receptor type 2A mutation and microsatellite instability in gastric cancer2017

    • Author(s)
      Yuza K,Nagahashi M,Ichikawa H,Shimada Y,Nakajima M,Takabe K,Wakai T
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10579
  • [Presentation] Sphingosine-1-phosphate in the Lymphatic Fluid Determined by Novel Methods2017

    • Author(s)
      Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K
    • Organizer
      The 12th Annual Academic Surgical Congress
    • Place of Presentation
      Las Vegas, USA
    • Year and Date
      2017-02-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] γH2AX expression discriminates between benign and malignant biliary tract biopsy specimens2017

    • Author(s)
      Yuki HIROSE, Masayuki NAGAHASHI, Hirosuke ISHIKAWA, Kizuki YUZA, Kohei MIURA, Hiroshi ICHIKAWA, Yoshifumi SHIMADA, Hitoshi KAMEYAMA, Jun SAKATA, Takashi KOBAYASHI, Toshifumi WAKAI
    • Organizer
      Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10691
  • [Presentation] 周術期末梢静脈栄養 脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果.2017

    • Author(s)
      諸 和樹, 小山 諭, 永橋 昌幸, 三浦 宏平, 土田 純子, 中島 真人, 若井 俊文.
    • Organizer
      第54回日本外科代謝栄養学会
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Presentation] 周術期末梢静脈栄養:脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果2017

    • Author(s)
      諸 和樹、小山 諭、永橋昌幸、三浦宏平、土田純子、中島真人、若井俊文1
    • Organizer
      第54回日本外科代謝栄養学会
    • Place of Presentation
      朱鷺メッセ 新潟コンベンションセンター(新潟県新潟市)
    • Year and Date
      2017-07-06
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Presentation] MED 12 expression may be a significant prognosis prediction in colorectal cancer.2016

    • Author(s)
      Toge K, Shimada Y, Tajima Y, Kameyama H, Yagi R, Okamura T, Hirose Y, Sakata J, Kobayashi T, Ajioka Y, Wakai T
    • Organizer
      26th World Congress of International Association of Surgeons, Gastroenterologists and Oncologists
    • Place of Presentation
      Seoul, Korea
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10130
  • [Presentation] Clinical significance of NQO1 expression in nontumorous squamous epithelium of esophageal cancer patients2016

    • Author(s)
      Kosugi S, Ichikawa H, Hanyu T, Ishikawa T, Wakai T
    • Organizer
      15th World Congress of the International Society for Diseases of the Esophagus
    • Place of Presentation
      Singapore (Republic of Singapore)
    • Year and Date
      2016-09-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461971
  • [Presentation] 5-Aminolevulinic Acid-induced Fluorescence Relates to Prognosis in Pancreatic Cancer2016

    • Author(s)
      Masahiro Minagawa, Tetsuya Naito, Jun Hasegawa, Tatsuo Tani, Naohiro Shimakage, Kazuyasu Takizawa, Kabuto Takano, Toshifumi Wakai
    • Organizer
      71th General Meeting of the Japanese Society of Gastroenterological Surgery
    • Place of Presentation
      あわぎんホール(徳島県徳島市)
    • Year and Date
      2016-07-15
    • Data Source
      KAKENHI-PROJECT-26462055
  • [Presentation] 周術期末梢静脈栄養における脂肪乳剤とカルニチン投与の検討2016

    • Author(s)
      小山 諭、諸 和樹、永橋昌幸、三浦宏平、辰田久美子、土田純子、中島真人、若井俊文
    • Organizer
      第53回日本外科代謝栄養学会
    • Place of Presentation
      伊藤国際学術研究センター(東京都文京区)
    • Year and Date
      2016-07-07
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Presentation] 肥満を伴う乳癌患者における血清スフィンゴシン-1-リン酸の定量2016

    • Author(s)
      土田 純子, 永橋 昌幸, 遠藤 麻巳子, 大溪 彩香, 庭野 稔之, 辰田 久美子, 利川 千絵, 長谷川 美樹, 五十嵐 麻由子, 中島 真人, 小山 諭, 高部 和明, 若井 俊文
    • Organizer
      第78回 日本臨床外科学会総会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都港区)
    • Year and Date
      2016-11-24
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] 大腸癌化学療法におけるNQO1発現解析の意義2016

    • Author(s)
      亀山仁史,廣瀬雄己,島田能史,八木亮磨,田島陽介,岡村拓磨,中野雅人,市川 寛,永橋昌幸,坂田 純,小林 隆,若井俊文
    • Organizer
      JDDW 2016
    • Place of Presentation
      神戸コンベンションセンター(兵庫県神戸市)
    • Year and Date
      2016-11-05
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Presentation] スフィンゴシンキナーゼ欠損細胞の開発とその機能解析2016

    • Author(s)
      中島 真人, 永橋 昌幸, 土田 純子, 市川 寛, 島田 能史, 若井 俊文
    • Organizer
      第75回 日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] Clinical significance of NQO1 expression in patients with KRAS wild-type unresectable colorectal cancer2016

    • Author(s)
      Hitoshi Kameyama, Yuki Hirose, Yoshifumi Shimada, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Masayuki Nagahashi, Takashi Kobayashi, Toshifumi Wakai
    • Organizer
      IASGO 2016
    • Place of Presentation
      Seoul (South Korea)
    • Year and Date
      2016-09-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Presentation] 膵癌におけるアミノレブリン酸蛍光と予後との相関2016

    • Author(s)
      皆川昌広 内藤哲也 長谷川潤 谷達夫 島影尚弘滝沢一泰 高野可赴 若井俊文
    • Organizer
      第71回日本消化器外科学会総会
    • Place of Presentation
      アスティ徳島(徳島県、徳島市)
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-26462055
  • [Presentation] スフィンゴシンキナーゼ欠損細胞の開発とその機能解析2016

    • Author(s)
      中島 真人, 永橋 昌幸, 土田 純子, 市川 寛, 島田 能史, 若井 俊文
    • Organizer
      第75回 日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K15610
  • [Presentation] 検診発見および自己発見乳癌の臨床病理学的特徴と長期成績2016

    • Author(s)
      土田 純子, 永橋 昌幸, 諸 和樹, 庭野 稔之, 辰田 久美子, 利川 千絵, 長谷川 美樹, 萬羽 尚子, 五十嵐 麻由子, 小山 諭, 市川 寛, 中島 真人, 島田 能史, 坂田 純, 小林 隆, 亀山 仁史, 若井 俊文
    • Organizer
      第116回 日本外科学会定期学術集会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市北区)
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] 大腸癌における転写メディエーターMED12異常発現の臨床的意義.2016

    • Author(s)
      島田能史,田島陽介,亀山仁史,八木亮磨,岡村拓磨,中野雅人,坂田 純,小林 隆,小杉伸一,若井俊文.
    • Organizer
      第71回日本消化器外科学会総会
    • Place of Presentation
      アスティとくしま(徳島県、徳島市)
    • Data Source
      KAKENHI-PROJECT-15K10130
  • [Presentation] 胆汁酸はスフィンゴシン-1-リン酸シグナル伝達系を介して 肝臓における脂質代謝を調節している2015

    • Author(s)
      永橋 昌幸,廣瀬 雄己,須藤 翔,大橋 拓,滝沢 一泰,高野 可赴,坂田 純,小林 隆,若井 俊文
    • Organizer
      第51日本胆道学会学術集会
    • Place of Presentation
      ホテル東日本宇都宮(栃木県宇都宮市)
    • Year and Date
      2015-09-17
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] 肝胆膵「肝胆膵外科診療の最前線」2015

    • Author(s)
      若井俊文
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2015-10-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] 肥満はスフィンゴシン-1-リン酸を癌微小環境において増加させる2015

    • Author(s)
      永橋 昌幸,諸 和樹,土田 純子,辰田 久美子,利川 千絵,長谷川 美樹,萬羽 尚子,五十嵐 真由子,坂田 純,小林 隆,亀山 仁史,皆川 昌広,小杉 伸一,小山 諭,高部 和明,若井 俊文
    • Organizer
      第115回日本外科学会定期学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-04-16
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] IMPACT OF SURGICAL RESECTION AND CHEMOTHERAPY ON LONG-TERM OUTCOMES IN PATIENTS WITH LOCALLY ADVANCED GALLBLADDER CARCINOMA2015

    • Author(s)
      T. Wakai, J. Sakata, Y. Hirose, N. Sudo, T. Katada, K. Takizawa, M. Nagahashi, T. Kobayashi
    • Organizer
      46th World Congress of Surgery
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2015-08-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] SymposiumⅢ Laparoscopic cholecystectomy with LN dissection2015

    • Author(s)
      Toshifumi Wakai
    • Organizer
      The 36th Annual Meeting of the Korean Society of Endoscopic & Laparoscopic Surgeons, 2015 International Symposium
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2015-05-29
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] LONG-TERM OUTCOMES OF SURGICAL RESECTION FOR EARLY GALLBLADDER CARCINOMA2015

    • Author(s)
      T. Wakai, J. Sakata, Y. Hirose, N. Sudo, T. Katada, K. Takizawa, M. Nagahashi, T. Kobayashi
    • Organizer
      46th World Congress of Surgery
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2015-08-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04927
  • [Presentation] Expression of NQO1 in esophageal cancer cells after neoadjuvant chemotherapy2014

    • Author(s)
      Takashi Ishikawa, Shin-ichi Kosugi, Hiroshi Ichikawa, Takaaki Hanyu, Tsutomu Suzuki, Toshifumi Wakai
    • Organizer
      14th World Congress of The International Society for Diseases of the Esophagus
    • Place of Presentation
      The Westin Bayshore(バンクーバー、カナダ)
    • Year and Date
      2014-09-24
    • Data Source
      KAKENHI-PROJECT-26461971
  • [Presentation] "Extended" radical cholecystectomy for gallbladder cancer2014

    • Author(s)
      Sakata J, Wakai T, Hirose Y, Katada T, Sudo N, Ohashi T, Takizawa K, Takano K, Kobayashi T, Minagawa M.
    • Organizer
      IHPBA World Congress 2014
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-03-25
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Presentation] 大腸粘膜下層浸潤癌における簇出(budding)の組織学的評価2014

    • Author(s)
      岡村拓磨、島田能史、若井俊文、味岡洋一
    • Organizer
      日本大腸肛門病学会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-11-07
    • Data Source
      KAKENHI-PROJECT-26462007
  • [Presentation] 表層拡大進展を伴う広範囲胆管癌に対する術前評価と外科治療戦略2014

    • Author(s)
      若井俊文,堅田朋大,須藤 翔,齋藤敬太,丸山智宏,滝沢一泰,坂田 純,高野可赴,小林 隆,皆川昌広
    • Organizer
      第69回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-24592021
  • [Presentation] Regional lymphadenectomy for gallbladder cancer : rational extent and patient outcomes2014

    • Author(s)
      Sakata J, Wakai T, Hirose Y, Katada T, Sudo N, Ohashi T, Takizawa K, Takano K, Kobayashi T, Minagawa M.
    • Organizer
      IHPBA World Congress 2014
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-03-25
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Presentation] VALPROIC ACID CONFERS RESISTANCE TO SORAFENIB IN MICE WITH HEPATOCELLULAR CARCINOMA2013

    • Author(s)
      Y. Matsuda, M. Osawa, S. Fujimaki, T. Wakai, M. Kubota, M. Takamura, S. Yamagiwa, Y. Aoyagi
    • Organizer
      欧州消化器病学会
    • Place of Presentation
      ベルリン(ドイツ)
    • Data Source
      KAKENHI-PROJECT-24590962
  • [Presentation] 潰瘍性大腸炎の炎症性発癌過程におけるDNA損傷2013

    • Author(s)
      谷 優佑、味岡洋一、 渡辺佳緒里、若井俊文、山口尚之、高林広明、小林和恵
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23590391
  • [Presentation] Assessment of lymph node status in gallbladder cancer: location, number, or ratio of positive nodes2013

    • Author(s)
      Sakata J, Ohashi T, Hirose Y, Takizawa K, Takano K, Kobayashi T, Minagawa M, Wakai T
    • Organizer
      International Surgical Week 2013
    • Place of Presentation
      Helsinki, Finland
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Presentation] 潰瘍性大腸炎の炎症性発癌過程におけるDNA損傷応答2013

    • Author(s)
      谷優佑, 味岡洋一, 渡辺佳緒里, 若井俊文, 山口尚之, 高林広明, 小林和恵
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2013-06-07
    • Data Source
      KAKENHI-PROJECT-23590391
  • [Presentation] Assessment of lymph node status in gallbladder cancer : location, number, or ratio of positive nodes2013

    • Author(s)
      Sakata J, Ohashi T, Hirose Y, Takizawa K, Takano K, Kobayashi T, Minagawa M, Wakai T.
    • Organizer
      International Surgical Week 2013
    • Place of Presentation
      Helsinki, Finland
    • Data Source
      KAKENHI-PROJECT-23592004
  • [Presentation] 大腸腫瘍の発育進展における, 53BP1を介したDNA損傷修復応答の変化2011

    • Author(s)
      高林広明, 味岡洋一, 若井俊文.
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-23590391
  • [Presentation] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011

    • Author(s)
      Wakai T, Shirai Y, Sakata J, Korita PV, Nagahashi M, Ajioka Y, Hatakeyama K
    • Organizer
      INTERNATIONAL SURGICAL WEEK 2011
    • Place of Presentation
      Yokohama
    • Year and Date
      2011-09-01
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] Early DNA Damage Response and Local Recurrence at Ductal Resection Margins in Patients Undergoing Resection for Extrahepatic Cholangiocarcinoma2010

    • Author(s)
      Wakai T, Shirai Y, Sakata J, Korita PV, Nagahashi M, Hatakeyama K
    • Organizer
      96th Annual Clinical Congress, American College of Surgeons
    • Place of Presentation
      Washington, DC
    • Year and Date
      2010-10-05
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] 肝門部胆管癌術後の胆管切離断端部遺残腫瘍におけるDNA damage responseと予後との関連2010

    • Author(s)
      若井俊文, 他
    • Organizer
      第65回日本消化器外科学会総会
    • Place of Presentation
      下関
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] <ワークショップ>肝門部胆管癌術後の胆管切離断端部遺残腫瘍におけるDNA damage responseと予後との関連2010

    • Author(s)
      若井俊文,白井良夫,坂田純,永橋昌幸,井上真,畠山勝義
    • Organizer
      第65回日本消化器外科学会総会
    • Place of Presentation
      下関
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] 胆管癌における53BP1を介したDNA損傷修復機構の解明及びその臨床的意義2009

    • Author(s)
      若井俊文
    • Organizer
      第17回日本消化器関連学会週間 JDDW 2009
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] 胆管断端における癌遺残が肝外胆管癌根治術後の遠隔成績に与える影響2009

    • Author(s)
      若井俊文,白井良夫,坂田純,金子和弘,永橋昌幸,畠山勝義
    • Organizer
      第64回日本消化器外科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] 胆管癌における53BP1を介したDNA損傷修復機構の解明及びその臨床的意義2009

    • Author(s)
      若井俊文,白井良夫,松田康伸,坂田純,味岡洋一,畠山勝義
    • Organizer
      第17回日本消化器関連学会週間JDDW 2009
    • Place of Presentation
      京都
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] 胆管癌根治切除後の胆管切離断端部遺残腫瘍におけるDNA damage responseと局所再発との関連2009

    • Author(s)
      若井俊文
    • Organizer
      第45回日本胆道学会学術集会
    • Place of Presentation
      東京ベイ幕張(千葉)
    • Year and Date
      2009-09-18
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] 胆管癌根治切除後の胆管切離断端部遺残腫瘍におけるDNA damage responseと局所再発との関連2009

    • Author(s)
      若井俊文,白井良夫,坂田純,金子和弘,永橋昌幸,畠山勝義
    • Organizer
      第45回日本胆道学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2009-09-18
    • Data Source
      KAKENHI-PROJECT-21591768
  • [Presentation] 脈管侵襲を伴う肝細胞癌における細胞接着因子の臨床的意義2007

    • Author(s)
      Pavel Korita, 若井俊文, 白井良夫, 他
    • Organizer
      第107回日本外科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Presentation] Clinical significance of cell adhesion molecules in hepatocellular carcinoma with vascular invasion2007

    • Author(s)
      Korita, P, Wakai, T, Shirai, Y, et. al.
    • Organizer
      The 107th Annual Congress of Japan Surgical Society
    • Place of Presentation
      Osaka
    • Year and Date
      2007-04-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591504
  • [Presentation] TGF-BETA IS A CRITICAL MEDIATOR OF SORAFENIB RESISTANCE IN HEPATOCELLULAR CARCINOMA

    • Author(s)
      Y. Matsuda, M. Osawa, T. Wakai, M. Kubota
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24590962
  • [Presentation] NQO1 EXPRESSION HAS PROGNOSTIC SIGNIFICANCE IN KRAS-WILD UNRESECTABLE COLORECTAL CANCER

    • Author(s)
      Y. Hirose, H. Kameyama, T. Ohashi, K. Takizawa, M. Nagahashi, T. Kobayashi, J. Sakata, T. Wakai
    • Organizer
      46th World Congress of Surgery
    • Place of Presentation
      Bangkok
    • Year and Date
      2015-08-23 – 2015-08-27
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Presentation] 5-Aminolevulinic Acid-induced Fluorescence Relates to the Gemcitabine Clearance in Pancreatic Cancer

    • Author(s)
      Masahiro Minagawa, Kazuyasu Takizawa, Kohei Miura, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
    • Organizer
      Asian-Pacific Hepato-Pancreato-Biliary Association
    • Place of Presentation
      シンガポール
    • Year and Date
      2015-03-18 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-26462055
  • [Presentation] 進行再発大腸癌におけるNQO1発現の臨床的意義

    • Author(s)
      亀山仁史,廣瀬雄己,佐藤 洋,山田沙季,阿部 馨,庭野稔之,岩城孝和,八木亮磨,田島陽介,中野麻恵,中野雅人,島田能史,坂田 純,小林 隆,皆川昌広,小杉伸一,小山 諭,若井俊文
    • Organizer
      第115回日本外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-04-16 – 2014-04-18
    • Data Source
      KAKENHI-PROJECT-26462006
  • [Presentation] 胆道癌として外科切除された良性胆管病変の検討

    • Author(s)
      若井俊文、坂田 純、皆川昌広
    • Organizer
      第49回日本胆道学会学術集会
    • Place of Presentation
      浦安
    • Data Source
      KAKENHI-PROJECT-24592021
  • [Presentation] Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma

    • Author(s)
      Toshifumi Wakai
    • Organizer
      11th World Congress oh the International Hepato-Pancreato-Biliary Association
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-24592021
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