ANDO Hideaki 安東英明

… Alternative Names

安東英明アンドウヒデアキ

Less

Researcher Number	50373262
Affiliation (based on the past Project Information) *help	2018 – 2019: 東京大学, 大学院医学系研究科(医学部), 特任准教授 2013: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員 2011 – 2012: 独立行政法人理化学研究所, 発生神経生物研究チーム, 研究員 2009 – 2010: The Institute of Physical and Chemical Research, 発生神経生物研究チーム, 客員研究員 2006: 理研, 研究員 2005: 独立行政法人理化学研究所, 発生神経生物研究チーム, 研究員
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 46030:Function of nervous system-related / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator IP3受容体 / カルシウム / タンパク質相互作用 / PIP2 / PIP kinase / IRBIT / カルシウムシグナル / 小胞体-ミトコンドリア接触部位 / 遺伝性疾患 / CA8 … More / 脊髄小脳失調症 / miRNA / マイクロRNA / イノシトールリン脂質 / PIP2合成酵素 / リン酸化 / calcium / IP3 Less

細胞内カルシウムチャネルの変異を原因とする神経変性疾患の発症機序解明Principal Investigator
- Principal Investigator
  
  安東英明
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  The University of Tokyo
Regulation of neuronal development by microRNAsPrincipal Investigator
- Principal Investigator
  
  ANDO Hideaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The Institute of Physical and Chemical Research
Regulation of phospholipid metabolisms by IRBIT familyPrincipal Investigator
- Principal Investigator
  
  ANDO Hideaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research
IP_3シグナルによるリン脂質代謝のフィードバック制御機構の解明Principal Investigator
- Principal Investigator
  
  安東英明
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2019 2018 2017 2014 2013 2011 2010 2009

All Journal Article Presentation Patent

[Journal Article] IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer2019
- Author(s)
  Adam Bartok, David Weaver, Tunde Golenar, Zuzana Nichtova, Mate Katona, Szava Bansaghi, Kamil J. Alzayady, V. Kaye Thomas, Hideaki Ando, Katsuhiko Mikoshiba, Suresh K. Joseph, David I. Yule, Gyorgy Csordas, Gyorgy Hajnoczky
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 3726-3726
- DOI
  10.1038/s41467-019-11646-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06540
[Journal Article] Aberrant IP3 receptor activities revealed by comprehensive analysis of pathological mutations causing spinocerebellar ataxia 292018
- Author(s)
  Ando Hideaki、Hirose Matsumi、Mikoshiba Katsuhiko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 48 Pages: 12259-12264
- DOI
  10.1073/pnas.1811129115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06540
[Journal Article] Remodeling of Ca2+ signaling in cancer: Regulation of inositol 1,4,5-trisphosphate receptors through oncogenes and tumor suppressors.2017
- Author(s)
  Ando H, Kawaai K, Bonneau B, Mikoshiba K.
- Journal Title
  
  Adv Biol Regul.
  
  Volume: pii: S2212-4926(17) Pages: 30188-4
- DOI
  10.1016/j.jbior.2017.12.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-18K06540
[Journal Article] IRBIT: A regulator of ion channels and ion transporters2014
- Author(s)
  Ando H, Kawaai K, Mikoshiba K
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 印刷中 Issue: 10 Pages: 2195-204
- DOI
  10.1016/j.bbamcr.2014.01.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458, KAKENHI-PROJECT-24700389, KAKENHI-PROJECT-25221002
[Journal Article] Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice2013
- Author(s)
  Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S
- Journal Title
  
  Gastroenterology
  
  Volume: 145(1) Pages: 232-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458
[Journal Article] A Genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis2013
- Author(s)
  Lesiak A, Pelz C, Ando H, Zhu M, Davare M, Lambert TJ, Hansen KF, Obrietan K, Appleyard SM, Impey S, Wayman GA
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 6 Pages: e64658-e64658
- DOI
  10.1371/journal.pone.0064658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458
[Journal Article] A genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis2013
- Author(s)
  Lesiak A, Pelz C, Ando H, Zhu M, Davare M, Lambert TJ, Hansen KF, Obrietan K, Appleyard SM, Impey S, Wayman GA
- Journal Title
  
  PLoS One
  
  Volume: 8(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458
[Journal Article] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice.2013
- Author(s)
  Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S
- Journal Title
  
  Gastroenterology
  
  Volume: S0016-5085(13) Issue: 1 Pages: 232-241
- DOI
  10.1053/j.gastro.2013.03.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458, KAKENHI-PROJECT-24590332, KAKENHI-PROJECT-24591225, KAKENHI-PROJECT-24700389, KAKENHI-PROJECT-25221002
[Journal Article] IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway2011
- Author(s)
  Yang D, Li Q, So I, Huang CL, Ando H, Mizutani A, Seki G, Mikoshiba K, Thomas PJ, Muallem S
- Journal Title
  
  J. Clin. Invest
  
  Volume: 121(3) Pages: 956-965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500458
[Journal Article] IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.2011
- Author(s)
  Yang D, Li Q, So I, Huang CL, Ando H, Mizutani A, Seki G, Mikoshiba K, Thomas PJ, Muallem S
- Journal Title
  
  J.Clin.Invest. 121(3)
  
  Pages: 956-965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21870049
[Journal Article] Isolation of inositol 1,4,5-trisphosphate receptor-associating proteins and selective knockdown using RNA interference.2010
- Author(s)
  Mizutani A, Kawaai K, Hisatsune C, Ando H, Michikawa T, Mikoshiba K
- Journal Title
  
  Methods Mol.Biol. 645
  
  Pages: 133-141
- Data Source
  KAKENHI-PROJECT-21870049
[Journal Article] An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage.2010
- Author(s)
  Ando H, Mizutani A, Mikoshiba K
- Journal Title
  
  J.Neurochem. 109(2)
  
  Pages: 539-550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21870049
[Journal Article] Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.2009
- Author(s)
  Kiefer H, Mizutani A, Iemura S, Natsume T, Ando H, Kuroda Y, Mikoshiba K
- Journal Title
  
  J.Biol.Chem. 284(16)
  
  Pages: 10694-10705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21870049
[Journal Article] IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct.2009
- Author(s)
  Yang D, Shcheynikov N, Zeng W, Ohana E, So I, Ando H, Mizutani A, Mikoshiba K, Muallem S
- Journal Title
  
  J.Clin.Invest. 119(1)
  
  Pages: 193-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21870049
[Patent] Control of intercellular target molecule by IP3 receptor-binding protein2013
- Inventor(s)
  Mikoshiba K, Ando H, Mizutani A
- Industrial Property Rights Holder
  科学技術振興機構
- Acquisition Date
  2013-03-13
- Overseas
- Data Source
  KAKENHI-PROJECT-23500458
[Patent] Control of function of intracellular Ca ion2010
- Inventor(s)
  Mikoshiba K, Mizutani A, Ando H
- Industrial Property Rights Holder
  Japan Science and Technology Agency
- Acquisition Date
  2010-05-04
- Overseas
- Data Source
  KAKENHI-PROJECT-21870049
[Patent] 細胞内Caイオンの機能制御2010
- Inventor(s)
  御子柴克彦、廣田順二、安東英明
- Industrial Property Rights Holder
  独立行政法人科学技術振興機構
- Acquisition Date
  2010-03-12
- Data Source
  KAKENHI-PROJECT-21870049
[Presentation] 遺伝性運動失調症の原因となるIP3受容体I型及びその制御タンパク質CA8の点突然変異体の解析2019
- Author(s)
  安東英明, 廣瀬松美, 御子柴克彦
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06540
[Presentation] 脊髄小脳失調症29型で同定されたIP3受容体I型の突然変異体の機能解析2019
- Author(s)
  安東英明, 廣瀬松美, 御子柴克彦
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06540
[Presentation] Multiple functions of an IP3 receptor binding protein, IRBIT2011
- Author(s)
  Ando H, Shirakabe K, Kiefer H, Mizutani A, Yamada H, Seki G, Yang D, Muallem S, Mikoshiba K
- Organizer
  The 10th JBS Biofrontier Symposium: New Aspects of Phospholipid Biology and Medicine 2011
- Place of Presentation
  ルイガンスホテル(福岡)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-23500458
[Presentation] Multiple functions of an IP3 receptor binding protein, IRBIT2011
- Author(s)
  Hideaki Ando
- Organizer
  The 10th JBC Biofrontier Symposium, New Aspecs of Phospholipid Biology and Medicine 2011
- Place of Presentation
  ルイガンスホテル（福岡）
- Data Source
  KAKENHI-PROJECT-23500458
[Presentation] IP3受容体結合タンパク質IRBITのホモログLong-IRBITの発現・機能解析2009
- Author(s)
  安東英明、水谷顕洋、御子柴克彦
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21870049

1. TAKENAWA Tadaomi (40101315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. IJUIN Takeshi (00361626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ITOH Toshiki (30313092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HISATSUNE Chihiro (10321803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUGAWARA Takeyuki (70584522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FURUTA Toshiaki (90231571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAWAAI Katsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ANDO Hideaki 安東 英明

安東 英明 アンドウ ヒデアキ

Research Projects

Research Products

Co-Researchers

細胞内カルシウムチャネルの変異を原因とする神経変性疾患の発症機序解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of neuronal development by microRNAsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of phospholipid metabolisms by IRBIT familyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IP_3シグナルによるリン脂質代謝のフィードバック制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aberrant IP3 receptor activities revealed by comprehensive analysis of pathological mutations causing spinocerebellar ataxia 292018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Remodeling of Ca2+ signaling in cancer: Regulation of inositol 1,4,5-trisphosphate receptors through oncogenes and tumor suppressors.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IRBIT: A regulator of ion channels and ion transporters2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice2013

Author(s)

Journal Title

Data Source

[Journal Article] A Genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis2013

Author(s)

Journal Title

Data Source

[Journal Article] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway2011

Author(s)

Journal Title

Data Source

[Journal Article] IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.2011

Author(s)

Journal Title

Data Source

[Journal Article] Isolation of inositol 1,4,5-trisphosphate receptor-associating proteins and selective knockdown using RNA interference.2010

Author(s)

Journal Title

Data Source

[Journal Article] An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage.2010

ANDO Hideaki 安東英明

安東英明アンドウヒデアキ