Uekita Talkamasa 上北尚正

… Alternative Names

上北尚正ウエキタタカマサ

UEKITA Takamasa 上北尚正

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Researcher Number	50373402
Other IDs
Affiliation (Current)	2025: 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群), 応用科学群, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群), 応用科学群, 准教授 2017: 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群), 応用科学群, 准教授 2016: 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工, 応用科学群, 准教授 2014 – 2015: 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工, その他部局等, 准教授 2013: 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工, 応用科学群, 准教授 … More 2010 – 2012: 独立行政法人国立がん研究センター, 研究所, 主任研究員 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 細胞増殖因子研究部, 主任研究官 2005 – 2006: 国立がんセンター(研究所及び東病院臨床開発センター), 細胞増殖因子研究部, 研究員 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 50010:Tumor biology-related / Tumor biology / Tumor biology Except Principal Investigator Basic Section 32020:Functional solid state chemistry-related
Keywords	Principal Investigator CDCP1 / 細胞運動能 / 足場非依存性 / シグナル伝達 / がん転移 / 複合体形成 / 癌転移 / MMP / 浸潤 / PKCδ … More / Src型キナーゼ / 足場非依存性増殖 / MT-SP1 / 足場非依存性能 / セリンプロテアーゼ / 多量体形成 / 膜型セリンプロテアーゼ / 細胞死 / 細胞内シグナル / Src / 低分子化合物 / MT1-MMP / Autophagy / ERK / Metastasis / Invasion / Ras / 細胞間接着 / がんの浸潤 / がんの浸潤・転移 / アノイキス … More Except Principal Investigator 光化学 / 金属錯体 / プロドラッグ / 外部刺激応答 / 配位子交換反応 / メタロドラッグ / 光異性化 / 光反応 / 抗がん剤 / 光配位子置換反応 / ルテニウム Less

Basic research on the development of new therapeutic methods for cancer metastasis targeting the CDCP1 extracellular domainPrincipal Investigator
- Principal Investigator
  
  Uekita Talkamasa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群)
Development of multi-stimuli-responsive metallodrugs
- Principal Investigator
  
  Hirahara Masanari
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 32020:Functional solid state chemistry-related
- Research Institution
  Osaka Institute of Technology
  防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群)
Basic research on cancer therapy development targeting anchorage independencePrincipal Investigator
- Principal Investigator
  
  Uekita Takamasa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群)
Analysis of the mechanism of cancer progression that overcome the cellular senescence by activated RasPrincipal Investigator
- Principal Investigator
  
  UEKITA TAKAMASA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群)
  National Center of Neurology and Psychiatry
Functional analysis of a novel signal molecule CDCP1 which regulates anchorage-independent growth in cancer cellsPrincipal Investigator
- Principal Investigator
  
  UEKITA Takamasa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
がん細胞の足場非依存性増殖におけるSrc型キナーゼの新規シグナル伝達機構の解明Principal Investigator
- Principal Investigator
  
  上北尚正
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2024 2023 2022 2021 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Ruthenium Pyrazole Complexes: A Family of Highly Active Metallodrugs for Photoactivated Chemotherapy2024
- Author(s)
  Hirahara Masanari、Iwamoto Aki、Teraoka Yuto、Mizuno Yuki、Umemura Yasushi、Uekita Takamasa
- Journal Title
  
  Inorganic Chemistry
  
  Volume: 63 Issue: 4 Pages: 1988-1996
- DOI
  10.1021/acs.inorgchem.3c03716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07165, KAKENHI-PROJECT-23K26766
[Journal Article] C9orf10/Ossa regulates the bone metastasis of established lung adenocarcinoma cell subline <scp>H322L‐BO4</scp> in a mouse model2024
- Author(s)
  Uekita Takamasa、Yagi Reiko、Ichimura Tohru、Sakai Ryuichi
- Journal Title
  
  Genes to Cells
  
  Volume: 29 Issue: 4 Pages: 290-300
- DOI
  10.1111/gtc.13103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07105, KAKENHI-PROJECT-21K05322, KAKENHI-PROJECT-21K07165
[Journal Article] An ionic liquid-assisted sample preparation method for sensitive integral-membrane proteome analysis2023
- Author(s)
  Masato Taoka, Kota Kamei, Akiko Kashima, Yuko Nobe, Takahiro Takekiyo, Takamasa Uekita, Tohru Ichimura
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 683 Pages: 115349-115349
- DOI
  10.1016/j.ab.2023.115349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05322, KAKENHI-PROJECT-21K07165
[Journal Article] The extracellular CUB domain of CDCP1 is involved in cell-cell contact and regulates collective cell migration in BxPC3 cells.2018
- Author(s)
  Sawayama T, Uekita T
- Journal Title
  
  Memoir NDA
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06850
[Journal Article] Novel small molecule inhibiting CDCP1-PKCδ pathway reduces tumor metastasis and proliferation.2017
- Author(s)
  Nakashima K, Uekita T, Yano S, Kikuchi JI, Nakanishi R, Sakamoto N, Fukumoto K, Nomoto A, Kawamoto K, Shibahara T, Yamaguchi H, Sakai R.
- Journal Title
  
  Cancer Sci.
  
  Volume: 印刷中 Issue: 5 Pages: 1049-1057
- DOI
  10.1111/cas.13218
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26290043, KAKENHI-PROJECT-15K06850, KAKENHI-PROJECT-16K14616, KAKENHI-PROJECT-16K14622
[Journal Article] A Sensitive Microbead-Based Organic Media-Assisted Method for Proteomics Sample Preparation from Dilute and Denaturing Solutions2017
- Author(s)
  Taoka Masato、Fujii Michihiko、Tsuchiya Masahiro、Uekita Takamasa、Ichimura Tohru
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 9 Issue: 49 Pages: 42661-42667
- DOI
  10.1021/acsami.7b16095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07764, KAKENHI-PROJECT-15K06850, KAKENHI-PROJECT-15K14427
[Journal Article] TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells.2017
- Author(s)
  Kawaguchi Y, Taoka M, Takekiyo T, Uekita T, Shoji I, Hachiya N, Ichimura T.
- Journal Title
  
  PLoS One
  
  Volume: １２（１） Issue: 1 Pages: 1-5
- DOI
  10.1371/journal.pone.0169436
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06850, KAKENHI-PROJECT-26660176
[Journal Article] Augmentation of invadopodia formation in temozolomide-resistant or adopted glioma is regulated by c-Jun terminal kinase-paxillin axis2015
- Author(s)
  Ueno H, Tomiyama A, Yamaguchi H, Uekita T et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 468 Issue: 1-2 Pages: 240-247
- DOI
  10.1016/j.bbrc.2015.10.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06850, KAKENHI-PROJECT-25430126, KAKENHI-PROJECT-25461494, KAKENHI-PROJECT-26290043
[Journal Article] Flotillin-1 regulates oncogenic signaling in neuroblastoma cells by regulating ALK membrane association.2014
- Author(s)
  Tomiyama A, Uekita T, Kamata R, Sasaki K, Takita J, Ohira M, Nakagawara A, Kitanaka C, Mori K, Yamaguchi H, Sakai R.
- Journal Title
  
  Cancer Res.
  
  Volume: 74(14) Issue: 14 Pages: 3790-3801
- DOI
  10.1158/0008-5472.can-14-0241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24501327, KAKENHI-PROJECT-25253095, KAKENHI-PROJECT-25430126, KAKENHI-PROJECT-25461402, KAKENHI-PROJECT-26290043, KAKENHI-PROJECT-26293242, KAKENHI-PROJECT-26461603, KAKENHI-PROJECT-26670493
[Journal Article] Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis2014
- Author(s)
  Uekita T, Fujii S et al.
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 12 Issue: 10 Pages: 1449-1459
- DOI
  10.1158/1541-7786.mcr-13-0587
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24501327, KAKENHI-PROJECT-26290043
[Journal Article] Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells.2013
- Author(s)
  Uekita T, Fujii S, Miyazawa Y, Hashiguchi A, Abe H, Sakamoto M, Sakai R.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 7 Pages: 865-870
- DOI
  10.1111/cas.12154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300353, KAKENHI-PROJECT-24501327, KAKENHI-PUBLICLY-23112524
[Journal Article] CDCP1 regulates the function of MT1-MMP and invadopodia-mediated invasion of cancer cells.2013
- Author(s)
  Miyazawa Y, Uekita T, Ito Y, Seiki M, Yamaguchi H, Sakai R.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 11(6) Issue: 6 Pages: 628-37
- DOI
  10.1158/1541-7786.mcr-12-0544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-23300353, KAKENHI-PROJECT-24501327, KAKENHI-PROJECT-25430126
[Journal Article] Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis2011
- Author(s)
  Uekita T. and Sakai R
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 11 Pages: 1943-1948
- DOI
  10.1111/j.1349-7006.2011.02052.x
- NAID
  10030244592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590350, KAKENHI-PUBLICLY-23112524, KAKENHI-PROJECT-23300353
[Journal Article] Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis2011
- Author(s)
  Tkamasa Uekita, Ryuichi Sakai
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 1943-1948
- NAID
  10030244592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590350
[Journal Article] CUB Domain-Containing Protein 1, a Prognostic Factor for Human Pancreatic Cancers, Promotes Cell Migration and Extracellular Matrix Degradation2010
- Author(s)
  Y.Miyazawa, T.Uekita, et al.(他6名)
- Journal Title
  
  Cancer Research 70(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590350
[Journal Article] CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation2010
- Author(s)
  Miyazawa Y., Uekita T., Hiraoka N., Fujii S., Kosuge T., Kanai Y., Nojima Y. and Sakai R.
- Journal Title
  
  Cancer Res
  
  Volume: 70 Issue: 12 Pages: 5136-5146
- DOI
  10.1158/0008-5472.can-10-0220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590350
[Journal Article] CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation.2010
- Author(s)
  Y.Miyazawa, T.Uekita, et al., 他6名
- Journal Title
  
  Cancer Research
  
  Volume: 70 Pages: 5136-5146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590350
[Journal Article] Expression of CUB domain containing protein(CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung2009
- Author(s)
  Ikeda JI., Oda T., Inoue M., Uekita T., Sakai R., Okumura M., Aozasa K. and Morii E.
- Journal Title
  
  Cancer Sci
  
  Volume: 100 Issue: 3 Pages: 429-433
- DOI
  10.1111/j.1349-7006.2008.01066.x
- NAID
  10025143186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590350
[Journal Article] Expression of CUB domain containing protein(CDCP1)is correlated with prognosis and survival of patients with adenocarcinoma of lung2009
- Author(s)
  J.Ikeda, T.Uekita, E.Morii, et al.(他4名)
- Journal Title
  
  Cancer Science 100
  
  Pages: 429-433
- NAID
  10025143186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] Regulatory mechanism of cancer metastasis via CDCP1 cleavage by membrane-type serine protease MT-SP12023
- Author(s)
  上北尚正、浅見佳紀
- Organizer
  第32回日本がん転移学会が駆出集塊・総会
- Data Source
  KAKENHI-PROJECT-21K07165
[Presentation] C9orf10/Ossa regulates bone metastasis of established lung adenocarcinoma sub-line H322L-BO4 cells in mouse model2023
- Author(s)
  上北尚正、八木玲子、市村徹、堺隆一
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07165
[Presentation] Ruthenium Pyrazole-Pyrazolate Complexes: Unique Photosubstitution Reactions and Applications to Photoactivated Chemotherapeutic Prodrugs2023
- Author(s)
  Masanari HIRAHARA, Yuto TERAOKA, Keiichi FUJIMORI, Takayo MORIUCHI, Takamasa UEKITA
- Organizer
  錯体化学会　第72回討論会
- Data Source
  KAKENHI-PROJECT-20K05456
[Presentation] MT-SP1によるCDCP1同種２量体形成の制御機構の解析2022
- Author(s)
  浅見佳紀、上北尚正
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K07165
[Presentation] Analysis of the control mechanism of cancer metastasis though CDCP1 cleaved by membrane serine protease MT-SP１.2022
- Author(s)
  Y. Asami, T. Uekita
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07165
[Presentation] Analysis of regulatory mechanism of cancer metastasis via CDCP1 cleavage by MT-SP1.2022
- Author(s)
  Y.Asami, T.Uekita
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07165
[Presentation] 膜型セリンプロテアーゼMT-SP1によるCDCP1切断を介した癌転移制御機構の解析2022
- Author(s)
  浅見佳紀、上北尚正
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07165
[Presentation] Analysis of the control mechanism of CDCP1 homophilic complex formation by MTSP12021
- Author(s)
  Y. Asami, T. Uekita
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07165
[Presentation] CDCP1細胞外ドメイン依存的な同種多量体形成を介した足場非依存性能の制御機構の解明2017
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] Homophilic complex formation of CDCP1 by CUB2 domain regulates lung cancer invasion.2017
- Author(s)
  Sawayama T, Uekita T
- Organizer
  NCRI Cancer Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] The possibility of CUB2 domain of CDCP1 extracellular domain as a novel therapeutic target for cancer metastasis.2017
- Author(s)
  澤山忠司、上北尚正
- Organizer
  CinBio 2017
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] Analysis of FAK-mediated anchorage-independent cell growth in small cell lung cancer.2017
- Author(s)
  上北尚正
- Organizer
  第26回がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] Cleavage of CDCP1 regulates signaling of anchorage-independence through its homophilic complex formation.2017
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第26回がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] CDCP1細胞外ドメインによる同種2量体形成はSrcを活性化し癌の足場非依存性を制御する2016
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第25回日本がん転移学会学術集会・総会
- Place of Presentation
  米子コンベンションセンター
- Year and Date
  2016-07-21
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] CDCP1細胞外ドメインによる同種多量体形成はSrcを活性化し肺がん転移を亢進する2016
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第39回分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] Dimerization of CDCP1 via extracellular domain regulates anchorage independence by activating Src signaling2016
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] CDCP1は細胞外ドメインによる同種複合体形成を介してがん細胞の運動能を制御する2015
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第７４回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] CDCP1細胞外ドメインは，同種２量体形成によってがん細胞の運動能を制御する。2015
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第２４回日本がん転移学会学術集会/総会
- Place of Presentation
  シティプラザ大阪
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] CDCP1細胞外ドメインは，同種多量体形成によってがん細胞の運動能を促進する。2015
- Author(s)
  澤山忠司、上北尚正
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06850
[Presentation] Oncogenic Ras-ERK signaling requires activation of CDCP1 pathway for promotion of tumor metastasis2013
- Author(s)
  Ryuichi Sakai, Takamasa Uekita
- Organizer
  9th AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui, USA
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] CDCP1はMT1-MMPの機能と浸潤突起を介したがん細胞の浸潤を制御する2013
- Author(s)
  上北尚正、山口英樹、堺隆一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] 新規ALK結合蛋白質であるFlotillin-1はendocytosisを介してALKシグナルを制御する2013
- Author(s)
  富山新太、上北尚正、堺隆一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] 癌細胞の足場非依存性におけるCDCP1シグナルを介したAutophagy抑制の重要性2013
- Author(s)
  上北尚正
- Organizer
  第22回日本がん転移学会学術集会・総会
- Place of Presentation
  長野
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] ALKのネガティブレギュレータFLOT1の神経芽腫における役割2013
- Author(s)
  富山新太、上北尚正
- Organizer
  第19回神経芽腫研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] CDCP1 regulates the function of MT1-MMP and invadopodia-mediated invasion of Cancer cells2013
- Author(s)
  T Uekita, R Sakai
- Organizer
  The 7th Mechanisms & Models of Cancer
- Place of Presentation
  Salk Inst.　La Jolla USA
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] Ras-ERKシグナルによる癌の転移能の亢進はCDCP1発現誘導を介する2012
- Author(s)
  上北尚正
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] 癌の足場非依存性と浸潤・転移を制御する新規因子CDCP1の解析2012
- Author(s)
  上北尚正、堺隆一
- Organizer
  平成23年度「個体レベルでのがん研究支援活動」ワークショップ個体レベルのがん研究のパラダイムー動物発がんモデルと分子機構の解明-
- Place of Presentation
  琵琶湖ホテル、滋賀県大津市
- Year and Date
  2012-01-19
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] CDCP1はRasにより発現誘導され、癌細胞の足場非依存性及び、浸潤・転移に関与する2012
- Author(s)
  上北尚正
- Organizer
  第21回日本がん転移学会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] 新規ALK結合蛋白質Flotillin-1はendocytosisを介してALKシグナルを制御する2012
- Author(s)
  富山新太、上北尚正
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] 癌の足場非依存性と浸潤・転移を制御する新規因子CDCP1の解析2012
- Author(s)
  上北尚正、堺隆一
- Organizer
  平成23年度「個体レベルでのがん研究支援活動」ワークショップ個体レベルのがん研究のパラダイム-動物発がんモデルと分子機構の解明-
- Place of Presentation
  琵琶湖ホテル
- Year and Date
  2012-01-19
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] Flotillin-1 is a novel ALK binding protein which regulates ALK signaling through receptor endocytosis2012
- Author(s)
  Arata Tomiyama, Takamasa Uekita
- Organizer
  Advances in Neuroblastoma Research Conference 2012
- Place of Presentation
  Tront, CA
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] Suppression of autophagy by CDCP1 is essential for anoikis resistance in cancer cells2011
- Author(s)
  Takamasa Uekita, Ryuichi Sakai
- Organizer
  70^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  NAGOYA CONGRESS CENTER, Nagoya, Japan
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] Suppression of autophagy by CDCP1 is essential for anoikis resistance in cancer cells2011
- Author(s)
  Uekita T. and Sakai R
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] CDCP1 Links Ras and Src Signaling Pathway as a Common Effector for the Promotion of Tumor Metastasis2011
- Author(s)
  Takamasa Uekita, Ryuichi Sakai
- Organizer
  The 6^<th> Mechanisms & Models of Cancer
- Place of Presentation
  Salk Inst., La Jolla, CA, USA
- Year and Date
  2011-08-14
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] CDCP1 links Ras and Src signaling pathway as a common effector for the promotion of tumor metastasis2011
- Author(s)
  Uekita T. and Sakai R
- Organizer
  The 6th Mechanisms & Models of Cancer
- Place of Presentation
  Salk
- Year and Date
  2011-08-14
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] がん細胞の浸潤に関与するCDCP1及び下流因子PKCδの機能解析2010
- Author(s)
  宮澤悠里、上北尚正、堺隆一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] 癌細胞の足場非依存性増殖におけるCDCP1のAutophagy抑制の重要性2010
- Author(s)
  上北尚正、堺隆一
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] Oncogenic Ras induces CDCP1 expression and regulates anoikis resistance, motility and invasion in cancer cells2010
- Author(s)
  Takamasa Uekita, Ryuichi Sakai, et al., 他2名
- Organizer
  69^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka international Convention Center RIHGA Royal Hotel Osaka
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] Oncogenic Ras induces CDCP1 expression and regulates anoikis resistance, motility and invasion in cancer cells2010
- Author(s)
  Uekita T. and Sakai R
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] 肺がんの骨転移モデル作製と骨転移関連因子の探索2010
- Author(s)
  八木玲子、上北尚正、堺隆一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] Regulation of metastasis and invasion by a novel Src substrate CDCP12009
- Author(s)
  Takamasa Uekita, Ryuichi Sakai
- Organizer
  68^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  PACIFICO YOKOHAMA
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] CDCP1は膵癌の転移・浸潤能に関わる予後因子である2009
- Author(s)
  上北尚正、堺隆一
- Organizer
  第18回日本がん転移学会学術集会・総会
- Place of Presentation
  旭川グランドホテル
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] Regulation of metastasis and invasion by a novel Src substrate CDCP12009
- Author(s)
  Uekita T. and Sakai R
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590350
[Presentation] CDCP1細胞外ドメインは、同種多量体形成によってがん細胞の運動能を促進する。
- Author(s)
  澤山忠司、上北尚正
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] Oncogenic Ras-ERK signaling activates CDCP1 pathway to promote tumor invasion and metastasis
- Author(s)
  上北尚正、堺隆一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501327
[Presentation] Analysis of anchorage-independent growth signaling in small cell lung cancer (SCLC)
- Author(s)
  上北尚正、堺隆一
- Organizer
  第23回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-24501327

1. YAMAGUCHI Hideki (10345035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. Hirahara Masanari (90609835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 堺隆一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. 市村徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 竹清貴浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 田岡万悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 市川美紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 中川原章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 藤井道彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 清木元治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uekita Talkamasa 上北 尚正

上北 尚正 ウエキタ タカマサ

UEKITA Takamasa 上北 尚正

Research Projects

Research Products

Co-Researchers

Basic research on the development of new therapeutic methods for cancer metastasis targeting the CDCP1 extracellular domainPrincipal Investigator

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Development of multi-stimuli-responsive metallodrugs

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Basic research on cancer therapy development targeting anchorage independencePrincipal Investigator

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Analysis of the mechanism of cancer progression that overcome the cellular senescence by activated RasPrincipal Investigator

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Functional analysis of a novel signal molecule CDCP1 which regulates anchorage-independent growth in cancer cellsPrincipal Investigator

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がん細胞の足場非依存性増殖におけるSrc型キナーゼの新規シグナル伝達機構の解明Principal Investigator

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[Journal Article] Ruthenium Pyrazole Complexes: A Family of Highly Active Metallodrugs for Photoactivated Chemotherapy2024

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[Journal Article] C9orf10/Ossa regulates the bone metastasis of established lung adenocarcinoma cell subline <scp>H322L‐BO4</scp> in a mouse model2024

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[Journal Article] An ionic liquid-assisted sample preparation method for sensitive integral-membrane proteome analysis2023

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[Journal Article] The extracellular CUB domain of CDCP1 is involved in cell-cell contact and regulates collective cell migration in BxPC3 cells.2018

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[Journal Article] Novel small molecule inhibiting CDCP1-PKCδ pathway reduces tumor metastasis and proliferation.2017

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[Journal Article] A Sensitive Microbead-Based Organic Media-Assisted Method for Proteomics Sample Preparation from Dilute and Denaturing Solutions2017

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[Journal Article] TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells.2017

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[Journal Article] Augmentation of invadopodia formation in temozolomide-resistant or adopted glioma is regulated by c-Jun terminal kinase-paxillin axis2015

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Uekita Talkamasa 上北尚正

上北尚正ウエキタタカマサ

UEKITA Takamasa 上北尚正