Yamamoto Kenji 山本兼司

… Alternative Names

山本兼司ヤマモトケンジ

KENJI Yamamoto 山本兼司

YAMAMOTO Kenji 山本兼司

Less

Researcher Number	50378775
Other IDs	https://orcid.org/0000-0003-1240-6369
Affiliation (Current)	2024: 独立行政法人国立病院機構南京都病院 (臨床研究部), 臨床研究部, 臨床研究部長(移行) 2024: 独立行政法人国立病院機構(宇多野病院臨床研究部), その他部局等, 研究員(移行)
Affiliation (based on the past Project Information) *help	2020 – 2022: 独立行政法人国立病院機構(宇多野病院臨床研究部), その他部局等, 研究員(移行) 2016: 独立行政法人国立病院機構(宇多野病院臨床研究部), その他部局等, 研究員(移行) 2011 – 2015: 独立行政法人国立病院機構(宇多野病院臨床研究部), その他部局等, 研究員 2008: 研究員 2008: 独立行政法人国立病院機構, 宇多野病院臨床研究部, 研究員 2007: 国立病院機構(宇多野病院臨床研究部), 研究員
Review Section/Research Field	Principal Investigator Neurology / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Neurology
Keywords	Principal Investigator カルシウム / レビー小体型認知症 / パーキンソン病 / オリゴマー / αシヌクレイン / カルシウムチャンネル / シナプス伝達 / 神経変性 / パッチクランプ / 膜興奮性 … More / カリウムチャンネル / homer / 3xTgマウス / homer1a / BKチャンネル / アミロイド前駆蛋白 / Homer / アミロイド前駆体蛋白 / アミロイドβ / 小胞体 / カルシウム結合蛋白 / カルシウム遊離 / IP3受容体 / ドーパミン … More Except Principal Investigator αシヌクレイ / Lewy小体 / プロテアソーム / 多系統萎縮症 / 不溶タンパク / 加齢 / ゲルろ過 / ミトコンドリア / ドパミン / オリゴマー / パーキンソン病 / 神経細胞死 Less

The analysis of aberrant machinery mediated by intraneural and extraneural alpha-synuclein oilgomersPrincipal Investigator
- Principal Investigator
  
  Yamamoto Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Utano National Hospital
The neuronal dysfunction by alpha-synuclein oligomers in Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  Yamamoto Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Department of Clinical Research, National Hospital Organization Utano National Hospital
analysis of abnormal neuronal excitability mediated by alpha-synuclein oligomerPrincipal Investigator
- Principal Investigator
  
  KENJI Yamamoto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Department of Clinical Research, National Hospital Organization Utano National Hospital
Relationship between neuronal death and inclusion body formation
- Principal Investigator
  
  SAWADA Hideyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Department of Clinical Research, National Hospital Organization Utano National Hospital

All 2022 2021 2020 2016 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Compassionate open- label use of rituximab following a randomised clinical trial against neuromyelitis optica (RIN-2 study): B cell monitoring-based administration.2022
- Author(s)
  Tahara M, Oeda T, Okada K, Ochi K, Maruyama H, Fukaura H, Nomura K, Shimizu Y, Nakashima I, Misu T, Umemura A, Yamamoto K, Sawada H.
- Journal Title
  
  Mult Scler Relat Disord.
  
  Volume: 60 Pages: 103730-103730
- DOI
  10.1016/j.msard.2022.103730
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07953, KAKENHI-PROJECT-22K07505, KAKENHI-PROJECT-20K07753
[Journal Article] Amyloid β and Amyloid Precursor Protein Synergistically Suppress Large-Conductance Calcium-Activated Potassium Channel in Cortical Neurons.2021
- Author(s)
  Yamamoto K, Yamamoto R, Kato N.
- Journal Title
  
  Front Aging Neurosci.
  
  Volume: 13 Pages: 660319-660319
- DOI
  10.3389/fnagi.2021.660319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07753, KAKENHI-PROJECT-21K07489, KAKENHI-PROJECT-21K11251, KAKENHI-PROJECT-18KK0468
[Journal Article] Complicity of α-synuclein oligomer and calcium dyshomeostasis in selective neuronal vulnerability in Lewy body disease.2021
- Author(s)
  Yamamoto K
- Journal Title
  
  Arch Pharm Res.
  
  Volume: 44 Issue: 6 Pages: 564-573
- DOI
  10.1007/s12272-021-01334-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07753
[Journal Article] Older-onset levodopa-responsive parkinsonism with normal DAT-SPECT and pterin hypometabolism.2021
- Author(s)
  Togo K, Ishihara T, Yamamoto K, Sawada H.
- Journal Title
  
  BMJ Case Rep.
  
  Volume: 14 Issue: 5 Pages: e240067-e240067
- DOI
  10.1136/bcr-2020-240067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07753
[Journal Article] Early-start vs delayed-start donepezil against cognitive decline in Parkinson disease: a randomized clinical trial.2021
- Author(s)
  Sawada H, Oeda T, Kohsaka M, Tomita S, Umemura A, Park K, Yamamoto K, Kiyohara K
- Journal Title
  
  Expert Opin Pharmacother.
  
  Volume: 22 Issue: 3 Pages: 363-371
- DOI
  10.1080/14656566.2020.1814255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07753
[Journal Article] Safety and efficacy of rituximab in neuromyelitis optica spectrum disorders (RIN-1 study): a multicentre, randomised, double-blind, placebo-controlled trial.2020
- Author(s)
  Tahara M, Oeda T, Okada K, Kiriyama T, Ochi K, Maruyama H, Fukaura H, Nomura K, Shimizu Y, Mori M, Nakashima I, Misu T, Umemura A, Yamamoto K, Sawada H.
- Journal Title
  
  Lancet Neurol.
  
  Volume: 19 Issue: 4 Pages: 298-306
- DOI
  10.1016/s1474-4422(20)30066-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07953, KAKENHI-PROJECT-20K07753, KAKENHI-PROJECT-18K07387
[Journal Article] Subclinical Elevation of Plasma C-Reactive Protein and Illusions/Hallucinations in Subjects with Parkinson’s Disease: Case–control Study2014
- Author(s)
  Sawada H et al.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e85886-e85886
- DOI
  10.1371/journal.pone.0085886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591265
[Journal Article] Trigger medications and patient-related risk factors for Parkinson disease psychosis requiring anti-psychotic drugs: a retrospective cohort study2013
- Author(s)
  Sawada H et al.
- Journal Title
  
  BMC Neurol.
  
  Volume: 13 Issue: 1 Pages: 145-145
- DOI
  10.1186/1471-2377-13-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591265
[Journal Article] Diagnostic Accuracy of Apparent Diffusion Coefficient and 123I-Metaiodobenzylguanidine for Differentiation of Multiple System Atrophy and Parkinson’s Disease2013
- Author(s)
  Umemura A, et al.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e61066-e61066
- DOI
  10.1371/journal.pone.0061066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591265
[Journal Article] Catecholamines and Neurodegeneration in Parkinson’s Disease―From Diagnostic Marker to Aggregations of α-Synuclein2013
- Author(s)
  Sawada H et al.
- Journal Title
  
  Diagnostics
  
  Volume: 3 Issue: 2 Pages: 210-221
- DOI
  10.3390/diagnostics3020210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591265
[Journal Article] Suppression of a neocortical potassium channel activity by intracellular amyloid-β and its rescue with Homer1a.2011
- Author(s)
  Yamamoto K, Ueta Y, Wang L, Yamamoto R, Inoue N, Inokuchi K, Aiba A, Yonekura H, Kato N.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31 Issue: 31 Pages: 11100-11109
- DOI
  10.1523/jneurosci.6752-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300106, KAKENHI-PROJECT-22500360, KAKENHI-PROJECT-23590349, KAKENHI-PROJECT-23591265, KAKENHI-PROJECT-23650214
[Journal Article] Suppression of a neocortical potassium channel activity by intracellular amyloid-β and its rescue with Homer1a.2011
- Author(s)
  Yamamoto K, et al.
- Journal Title
  
  J Neurosci.
  
  Volume: 31 Pages: 11100-11109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591265
[Journal Article] Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models2009
- Author(s)
  Takeuchi H, Yanagida T, Inden M, Takata K, Kitamura Y, Yamakawa K, Sawada H, Izumi Y, Yamamoto N, Kihara T, Uemura K, Inoue H, Taniguchi T, Akaike A, Takahashi R, Shimohama S.
- Journal Title
  
  J. Neurosci. Res 87
  
  Pages: 576-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease model2009
- Author(s)
  Takeuchi H, Yangagida T, Inden M, Takata K, Kitamura Y, Yamakawa K, Sawada H, Izumi Y, Yamamoto N, Kihara T, Uemura K, Inoue H, Taniguchi T, Akaike A, Takahashi R, Shimahama S.
- Journal Title
  
  J Nerosci Res 87
  
  Pages: 576-585
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] Vulnerability to glutamate toxicity of dopaminergic Neurons is dependent on endogenous dopamine and MAPK activation2009
- Author(s)
  Izumi Y, Yamamoto N, Matsuo T, Wakita S, Takeuchi H, Kume T, Katsuki H, Sawada H, Akaike A.
- Journal Title
  
  J. Neurochem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] Vulnerability to glutamate toxicity of dopaminergic neurons is dependent on endogenous dopamine and MAPK activation2009
- Author(s)
  Izumi Y, Yamamoto N, Matsuo T, Wakita S. Takeuchi H, Kume T, Katsuki H, Sawada H, Akaike A.
- Journal Title
  
  J Neurochem 110
  
  Pages: 745-755
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] Diagnositc accuracy of cardiac metaiodobenzylguanidine scintigraphy in Parkinson disease2009
- Author(s)
  Sawada H, Oeda T, Yamamoto K, Kitagwa N, Mizuta E, Hosokawa R, Ohba M, Nishio R, Yamakawa K, Takeuchi H, Shimohama S, Takahashi R, Kawamura T.
- Journal Title
  
  Eur. J. Neurol 16
  
  Pages: 174-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] Diagnostic accuracy of cardiac metaiodobenzylguanidine scintigraphy in Parkinson disease2009
- Author(s)
  Sawada H, Oeda T, Yamamoto K, Kitagawa N, Mizuta E, Hosokawa R, Ohba M, Nishio R, Yamakawa K, Takeuchi H, Shimohama S, Takahashi R, Kawamura T.
- Journal Title
  
  Eur J Neurol 16
  
  Pages: 174-182
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] High risk factors for valvular heart disease from dopamine agonists in patients with Parkinson's disease2009
- Author(s)
  Oeda T, Masaki M, Yamamoto K, Mizuta E, Kitagawa N, Isono T, Taniguchi S, Doi K, Yaku H, Yutani C, Kawamura T, Kuno S, Sawada H.
- Journal Title
  
  J. Neural Transm 116
  
  Pages: 171-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] Regulation of intracellular dopamine levels by dopaminergic drugs : Involvement of vesicular monoamine transporter2008
- Author(s)
  Izumi Y, Yamamoto N, Kume T, Katsuki H, Sawada H, Akaike A.
- Journal Title
  
  Eur J Pharmacol 582
  
  Pages: 52-61
- Data Source
  KAKENHI-PROJECT-19591026
[Journal Article] Dopamine facilitates a-synuclein oligomerization in human neuroblastoma SH-SY5Y cells
- Author(s)
  Yamakawa K, Izumi Y, Takeuchi H, Yamamoto N, Kume T, Akaike A, Takahashi R, Shimohama S, Sawada H.
- Journal Title
  
  Biochem Biophys Res Comm (in press)
- Data Source
  KAKENHI-PROJECT-19591026
[Presentation] パーキンソン病患者における嚥下機能障害の機序について～嚥下造影検査による検討2022
- Author(s)
  冨田聡, 大江田知子, 高坂雅之, 朴貴瑛, 石原稔也, 野元翔平, 斎藤慶介,田原将行, 山本兼司, 澤田秀幸
- Organizer
  第63回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病の側屈姿勢における垂直認知障害と右側側頭頭頂皮質との関係2022
- Author(s)
  高坂雅之, 大江田知子, 高屋成利, 冨田聡, 朴貴瑛, 石原稔也, 野元翔平, 山本兼司, 澤田秀幸
- Organizer
  第16回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] レボドパ代謝物3-O-methyldopaのパーキンソン病経過に及ぼす影響2022
- Author(s)
  大江田知子, 高坂雅之, 冨田聡, 朴貴瑛, 石原稔也, 野元翔平, 森裕子, 山本兼司, 澤田秀幸
- Organizer
  第16回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] THE MODE OF SYNERGISTIC SUPPRESSION ON LARGE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BY AMYLOID BETA OLIGOMER AND AMYLOID PRECURSOR PROTEIN2022
- Author(s)
  Yamamoto K, Yamamoto R, Kato N
- Organizer
  16th International Conference on Alzheimer’s & Parkinson’s Diseases (AD/PD2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病の睡眠障害に対するレボドパ・カルビドパ配合経腸用液療法の長期有効性2022
- Author(s)
  高坂雅之, 大江田知子, 冨田聡, 朴貴瑛, 石原稔也, 野元翔平, 山本兼司, 澤田秀幸
- Organizer
  第63回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] The mode of synergistic suppression on BK channel by Aβ oligomer and amyloid precursor protein2022
- Author(s)
  Yamamoto K, Yamamoto R, Kato N
- Organizer
  第63回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病における咳感受性低下は肺炎発症を予測する注目すべき非運動症状である2022
- Author(s)
  冨田聡, 大江田知子, 高坂雅之, 朴貴瑛, 石原稔也, 野元翔平, 齊藤慶介, 西野晃平, 水井大介, 高木宥磨, 米谷廉, 田原将行, 山本兼司, 澤田秀幸
- Organizer
  第16回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] 進行性核上性麻痺患者の臨床像の変化2022
- Author(s)
  石原稔也, 大江田知子, 野元翔平, 朴貴瑛, 髙坂雅之, 冨田聡, 田原将行, 山本兼司, 澤田秀幸
- Organizer
  第63回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病(PD)/レビー小体型認知症(DLB)の血圧日内変動と幻視2022
- Author(s)
  野元翔平, 大江田知子, 笠原仁菜, 内炭弘嗣, 冨田聡, 梅村敦史, 高坂雅之, 朴貴瑛, 石原稔也, 田原将行, 山本兼司, 澤田秀幸
- Organizer
  第63回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病(PD)/レビー小体型認知症(DLB)の異常な血圧変動と幻視の出現2022
- Author(s)
  野元翔平, 大江田知子, 内炭弘嗣, 冨田聡, 高坂雅之, 朴貴瑛, 石原稔也, 田原将行, 山本兼司, 澤田秀幸
- Organizer
  第16回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] レボドパ・カルビドパ配合経腸用液療法の長期有効性と安全性の検討2021
- Author(s)
  高坂雅之, 大江田知子, 梅村敦史, 冨田聡, 朴貴瑛, 山本兼司, 澤田秀幸
- Organizer
  第14回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] レボドパ・カルビドパ配合経腸用液療法の睡眠障害に対する長期効果2021
- Author(s)
  高坂雅之, 大江田知子, 冨田聡, 朴貴瑛, 石原稔也, 野元翔平, 山本兼司, 澤田秀幸
- Organizer
  第15回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] The mode of cooperative suppression on large conductance calcium-activated potassium channel by amyloid β oligomer and amyloid precursor protein2021
- Author(s)
  Yamamoto K, Yamamoto R, Kato N
- Organizer
  北米神経科学学会（Neuroscience 2021）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病認知機能に対するドネペジル早期治療群と遅発治療群のランダム比較試験2021
- Author(s)
  澤田秀幸, 大江田知子, 高坂雅之, 冨田聡, 梅村敦史, 朴貴瑛, 山本兼司, 田原将行, 清原康介
- Organizer
  第62回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病(PD)/レビー小体型認知症(DLB)の血圧変動と精神症状および認知症の関連2021
- Author(s)
  野元翔平, 冨井康宏, 大江田知子, 笠原仁菜, 内炭弘嗣, 冨田聡, 梅村敦史, 高坂雅之, 朴貴瑛, 石原稔也, 田原将行, 山本兼司, 戸田真太郎, 山本康正, 澤田秀幸
- Organizer
  第62回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] 進行性認知症とParkinsonismを呈し、黒質変性を認めたTDP-43 proteinopathyの1剖検例2021
- Author(s)
  冨田聡, 井上貴美子, 山下里佳, 大江田知子, 山本兼司, 高坂雅之, 朴貴瑛, 野元翔平, 石原稔也, 藤村晴俊,村山繁雄, 澤田秀幸
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] A clinicopathological case report of limbic-predominant age-related TDP-43 encephalopathy(LATE)2021
- Author(s)
  冨田聡, 井上貴美子, 山下里佳, 大江田知子, 山本兼司, 梅村敦史, 高坂雅之, 朴貴瑛, 野元翔平, 石原稔也, 藤村晴俊,村山繁雄, 澤田秀幸
- Organizer
  第62回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病/レビー小体型認知症(PD/DLB)の血圧変動と精神症状および認知症との関連2021
- Author(s)
  野元翔平, 冨井康宏, 大江田知子, 笠原仁菜, 内炭弘嗣, 冨田聡, 梅村敦史, 高坂雅之, 朴貴瑛, 石原稔也, 田原将行, 山本兼司, 戸田真太郎, 山本康正, 澤田秀幸
- Organizer
  第15回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] PD/DLBの概日血圧変動と精神症状および認知症との関連2021
- Author(s)
  野元翔平, 冨井康宏, 大江田知子, 笠原仁菜, 内炭弘嗣, 冨田聡, 梅村敦史, 高坂雅之, 朴貴瑛, 石原稔也, 田原将行, 山本兼司, 戸田真太郎, 山本康正, 澤田秀幸
- Organizer
  第14回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] THE COOPERATIVE SUPPRESSION OF LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BY AMYLOID BETA AND AMYLOID PRECURSORPROTEIN IN CORTICAL NEURONS2021
- Author(s)
  Yamamoto K, Yamamoto R, Kato N
- Organizer
  第24回 World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] 進行性核上性麻痺患者の垂直性眼球運動障害と生命予後の関係2021
- Author(s)
  石原稔也, 大江田知子, 朴貴瑛, 高坂雅之, 梅村敦史, 冨田聡, 田原将行, 山本兼司, 澤田秀幸
- Organizer
  第14回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病におけるドネペジルの疾患修飾効果 Delayed-start study2021
- Author(s)
  澤田秀幸, 大江田知子, 高坂雅之, 冨田聡, 梅村敦史, 朴貴瑛, 山本兼司, 田原将行, 清原康介
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] The mode of synergistic suppression on large conductance calcium-activated potassium channel by amyloid β and amyloid precursor protein2021
- Author(s)
  Yamamoto K, Yamamoto R, Kato N
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] アミロイドβとアミロイド前駆蛋白の協調によるBKチャンネル抑制様式2021
- Author(s)
  山本兼司，山本亮，加藤伸郎
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] レボドパ・カルビドパ配合経腸用液療法の長期有効性と安全性の検討2021
- Author(s)
  高坂雅之, 大江田知子, 梅村敦史, 冨田聡, 朴貴瑛, 山本兼司, 澤田秀幸
- Organizer
  第62回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] 進行性核上性麻痺における垂直性眼球運動障害と予後の関連2021
- Author(s)
  石原稔也, 大江田知子, 野元翔平, 朴貴瑛, 髙坂雅之, 梅村敦史, 冨田聡, 田原将行, 山本兼司, 澤田秀幸
- Organizer
  第62回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] 進行期パーキンソン病におけるレボドパ・カルビドパ配合経腸用液療法の長期有効性と安全性の検討2020
- Author(s)
  高坂雅之, 大江田知子, 梅村敦史, 冨田聡, 朴貴瑛, 山本兼司, 澤田秀幸
- Organizer
  第74回国立病院総合医学会
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病/レビー小体型認知症の概日血圧変動と精神症状および認知症の関連2020
- Author(s)
  野元翔平, 冨井康宏, 大江田知子, 笠原仁菜, 内炭弘嗣, 冨田聡, 梅村敦史, 高坂雅之, 朴貴瑛, 石原稔也, 田原将行, 山本兼司, 戸田真太郎, 山本康正, 澤田秀幸
- Organizer
  第61回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] パーキンソン病における咳感受性低下に関連する脳部位に関する検討2020
- Author(s)
  冨田聡, 大江田知子, 高屋成利, 高坂雅之, 朴貴瑛, 梅村敦史, 森裕子, 石原稔也, 野元翔平, 田原将行, 山本兼司, 澤田秀幸
- Organizer
  第61回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] レボドパ・カルビドパ配合経腸用液の長期投与における有効性と安全性の検討2020
- Author(s)
  高坂雅之, 大江田知子, 梅村敦史, 冨田聡, 朴貴瑛, 山本兼司, 澤田秀幸
- Organizer
  第61回日本神経学会学術会議
- Data Source
  KAKENHI-PROJECT-20K07753
[Presentation] Aberrant calcium release from IP3 receptor by α-synuclein oligomers: involvement of the calcium-binding protein2016
- Author(s)
  山本兼司、澤田秀幸
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] The mechanism of aberrant calcium release from IP3 receptor by intraneural alpha-synuclein oligomers2016
- Author(s)
  Kenji Yamamoto, Hideyuki Sawada
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] The involvement of the calcium binding protein in aberrant calcium release from IP3 receptor by alpha-synuclein oligomers2016
- Author(s)
  Kenji Yamamoto, Hideyuki Sawada
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] The mechanism of aberrant calcium release from IP3 receptor by intraneural alphasynuclein oligomers2016
- Author(s)
  山本兼司、澤田秀幸
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] Aberrant calcium release from IP3 receptor by alpha-synuclein oligomers: involvement of the calcium-binding protein2016
- Author(s)
  Kenji Yamamoto, Hideyuki Sawada
- Organizer
  第39 回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] αシヌクレインオリゴマーによる神経発火頻度抑制にはSKチャンネル・IP3受容体の機能連関が寄与する2015
- Author(s)
  山本兼司、澤田秀幸
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] α-synuclein oligomers suppress spike firing by strengthening functional coupling of L-type calcium channel, SK-type potassium channel, and inositol trisphosphate receptor in neocortical pyramidal neurons2015
- Author(s)
  Yamamoto K, Sawada H
- Organizer
  Annual Meeting of Society for Neuroscience 2015
- Place of Presentation
  米国、シカゴ
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] alpha-synuclein oligomers enhance functional coupling of SK, VDCC and IP3R2015
- Author(s)
  山本兼司、澤田秀幸
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] Down-regulation of spike frequency by alpha-synuclein oligomer2014
- Author(s)
  山本兼司他
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Down-regulation of spike frequency by alpha-synuclein oligomer2014
- Author(s)
  山本兼司、山川健太郎、澤田秀幸
- Organizer
  第55日本神経学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] αシヌクレインオリゴマーによる大脳皮質錐体細胞の発火制御機構2013
- Author(s)
  山本兼司、山川健太郎、澤田秀幸
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都
- Year and Date
  2013-06-20
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Suppression of spike frequency by α-Synuclein oligomer in neocortical pyramidal neurons2013
- Author(s)
  Yamamoto K et al.
- Organizer
  21th World Congress of Neurology
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] αシヌクレインオリゴマーは大脳皮質錐体細胞の発火頻度を低下させる2013
- Author(s)
  山本兼司、山川健太郎、澤田秀幸
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2013-05-29
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Suppression of spike frequency byα-Synuclein oligomer in neocortical pyramidal neurons2013
- Author(s)
  K. Yamamoto, K. Yamakawa, H. Sawada
- Organizer
  21^<th> World Congress of Neurology
- Place of Presentation
  Vienna, Austria
- Year and Date
  2013-09-24
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Nutritional status as a predictor of the mortality in patients with Parkinson's disease2012
- Author(s)
  Motoyama R, Oeda T, Hari Y, Hayashi R, Uemura A, Tomita S, Kohsaka M, Yamamoto K, Konishi T, Sawada H
- Organizer
  16^<th> Congress of the European Federation of Neurological Societies
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2012-09-09
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Levodopa responsiveness for progressive supranuclear palsy can predict early onset of aspiration pneumonia2012
- Author(s)
  Tomita S, Oeda T, Nakano H, Umemura A, Hayashi R, Yamamoto K, Sawada H
- Organizer
  16^<th> Congress of the European Federation of Neurological Societies
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2012-09-10
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Brain MRI apparent diffusion co-efficient (ADC) in Parkinson's disease with dementia2012
- Author(s)
  Umemura A, Oeda T, Kohsaka M,Tomita S, Hayashi R, Yamamoto K, Sawada H
- Organizer
  16^<th> Congress of the European Federation of Neurological Societies
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2012-09-09
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Ocular application of oxybuprocaine hydrochloride against apraxia of lid opening : a randomized controlled trial2012
- Author(s)
  Kohsaka M, Oeda T, Nakano H, Umemura A, Tomita S, Hayashi R, Yamamoto K, Sawada H
- Organizer
  16^<th> Congress of the European Federation of Neurological Societies
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2012-09-09
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Hallucinations and Delusions in Patients with Parkinson's Disease - Evaluation by the Parkinson Psychosis Questionnaire2011
- Author(s)
  Sawada H, Oeda T, Umemura A, Tomita S, Hayashi R, Kohsaka M, Nakano H, Yamamoto K
- Organizer
  15^<th> Congress of the European Federation of Neurological Societies
- Place of Presentation
  Budapest, Hungary
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] Role of Brain MRI Apparent Diffusion Coefficient (ADC) in the Differential Diagnosis of Parkinson's Disease (PD) and Progressive Supranuclear Palsy (PSP)2011
- Author(s)
  Umemura A, Oeda T, Kohsaka M,Tomita S, Hayashi R, Yamamoto K, Sawada H
- Organizer
  15^<th> Congress of the European Federation of Neurological Societies
- Place of Presentation
  Budapest, Hungary
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-23591265
[Presentation] ドパミン受容体リガンドによるドパミン含有量低下作用機序の解明2008
- Author(s)
  泉安彦, 山本憲幸, 久米利明, 澤田秀幸, 赤池昭紀
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜市
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19591026
[Presentation] Induction of heme oxygenase-1 by proteasome inhibition is involved in the protection of dopaminergic neurons : implication of ubiquitin-proteasome degradation2007
- Author(s)
  Yamamoto N, Sawada H, Izumi Y, et al.
- Organizer
  XVIIth WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam, Netherland
- Data Source
  KAKENHI-PROJECT-19591026
[Presentation] Cardiac metaiodobenzylguanidine scintigraphy as a peripheral biomarker for the diagnosis of Parkinson disease2007
- Author(s)
  Sawada H, Oeda T, Yamamoto K, et al.
- Organizer
  XVIIth WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam, Netherland
- Data Source
  KAKENHI-PROJECT-19591026
[Presentation] Cardiac metaiodobenzylguanidine scintigraphy as a peripheral biomarker for the diagnosis of Parkinson disease.2007
- Author(s)
  Sawada H, Oeda T, Yamamoto K, et. al.
- Organizer
  XVIIth WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam, Netherland
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19591026
[Presentation] Induction of heme oxygenase-1 by proteasome inhibition is involved in the protection of dopaminergic neurons : implication of ubiquitin-proteasome degradation.2007
- Author(s)
  Yamamoto N, Sawada H, Izumi Y, et. al.
- Organizer
  XVIIth WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam, Netherland
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19591026
[Presentation] alpha-synuclein oligomers enhance functional coupling of SK, VDCC and IP3R
- Author(s)
  Kenji Yamamoto, Hideyuki Sawada
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟、朱鷺メッセ
- Year and Date
  2015-05-20 – 2015-05-23
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] Inovolvement of SK-type calcium-activated potassium channel in α-synuclein oligomer-mediated suppression of spike frequency in neocorical
- Author(s)
  Kenji Yamamoto, Hideyuki Sawada
- Organizer
  Annual Meeting of Society for Neuroscience 2014
- Place of Presentation
  米国、シカゴ
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] Functional coupling of SK channel and IP3 receptor contibutes the suppression of spike frequency by α-synuclein oligomer
- Author(s)
  Kenji Yamamoto, Hideyuki Sawada
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸、神戸国際会議場
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] αシヌクレインオリゴマーによる大脳皮質錐体細胞の発火抑制機構
- Author(s)
  山本兼司、澤田秀幸、他
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡、福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461287
[Presentation] α-synuclein oligomers suppressed spike frequency by enhancing afterhyperpolarization in neocortical pyramidal neurons
- Author(s)
  Kenji Yamamoto, Hideyuki Sawada
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26461287

1. SAWADA Hideyuki (30335260)

# of Collaborated Projects: 4 results

# of Collaborated Products: 66 results
2. IZUMI Yasuhiko (60456837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. YAMAKAWA Kentaro (70447960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 三須建郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 饗場篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamoto Kenji 山本 兼司

山本 兼司 ヤマモト ケンジ

KENJI Yamamoto 山本 兼司

YAMAMOTO Kenji 山本 兼司

Research Projects

Research Products

Co-Researchers

The analysis of aberrant machinery mediated by intraneural and extraneural alpha-synuclein oilgomersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The neuronal dysfunction by alpha-synuclein oligomers in Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

analysis of abnormal neuronal excitability mediated by alpha-synuclein oligomerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between neuronal death and inclusion body formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Compassionate open- label use of rituximab following a randomised clinical trial against neuromyelitis optica (RIN-2 study): B cell monitoring-based administration.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Amyloid β and Amyloid Precursor Protein Synergistically Suppress Large-Conductance Calcium-Activated Potassium Channel in Cortical Neurons.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complicity of α-synuclein oligomer and calcium dyshomeostasis in selective neuronal vulnerability in Lewy body disease.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Older-onset levodopa-responsive parkinsonism with normal DAT-SPECT and pterin hypometabolism.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Early-start vs delayed-start donepezil against cognitive decline in Parkinson disease: a randomized clinical trial.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety and efficacy of rituximab in neuromyelitis optica spectrum disorders (RIN-1 study): a multicentre, randomised, double-blind, placebo-controlled trial.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Subclinical Elevation of Plasma C-Reactive Protein and Illusions/Hallucinations in Subjects with Parkinson’s Disease: Case–control Study2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trigger medications and patient-related risk factors for Parkinson disease psychosis requiring anti-psychotic drugs: a retrospective cohort study2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnostic Accuracy of Apparent Diffusion Coefficient and 123I-Metaiodobenzylguanidine for Differentiation of Multiple System Atrophy and Parkinson’s Disease2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Catecholamines and Neurodegeneration in Parkinson’s Disease―From Diagnostic Marker to Aggregations of α-Synuclein2013

Author(s)

Journal Title

DOI

Yamamoto Kenji 山本兼司

山本兼司ヤマモトケンジ

KENJI Yamamoto 山本兼司

YAMAMOTO Kenji 山本兼司