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Harada Yuka  原田 結花

ORCIDConnect your ORCID iD *help
… Alternative Names

原田 結花  ハラダ ユカ

HARADA Yuka  原田 結花

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Researcher Number 50379848
Other IDs
External Links
Affiliation (Current) 2019: 東京都立駒込病院(臨床研究室), 臨床試験科, 医長
Affiliation (based on the past Project Information) *help 2019: 東京都立駒込病院(臨床研究室), 臨床試験科, 医長
2017: 文京学院大学, 保健医療技術学部, 教授
2015 – 2016: 文京学院大学, 保健医療学部, 教授
2013 – 2014: 順天堂大学, 医学部, 助教
2007 – 2012: Hiroshima University, Research Institute for Radiation Biology and Medicine, Assistant Professor
2006: 広島大学, 原爆放射線医科学研究所, 助手
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
Hematology / Hygiene / Area studies / Risk sciences of radiation and chemicals / Basic Section 54010:Hematology and medical oncology-related / Medical genome science
Keywords
Principal Investigator
MLL / 骨髄異形成症候群 / RUNX1 / Evil / AML1 / BMI1 / RUNX1変異 / エトポシド / 急性骨髄性白血病 / ヒト造血幹細胞 … More / 急性前骨髄球性白血病 / 遺伝子転座 / キメラ遺伝子 / 転写因子 / 骨髄異形成／骨髄増殖性腫瘍 / Myelodysplastic syndrome / AMLl / Translocation / 治療関連白血病 / 骨髄異形成症候群（MDS） / 治療関連造血器腫瘍 / 造血幹細胞 / Evi1 / AML1/RUNX1遺伝子 / 放射線傷害耐性 / 低線量被曝 / 遺伝子異常 / Hematopoietic stem cells / ATRA / 遺伝子変異 / Partner gene mutations / 癌 / 協調遺伝子変異 / 家族性造血器腫瘍 / マウスBMTモデル / スプライシング因子変異 / 慢性骨髄単球性白血病 / Therapy related leukemia … More
Except Principal Investigator
骨髄異形成症候群 / セミパラチンスク / RUNX1 / 放射線障害 / カザフスタン / AML1 / コホート研究 / RUNX1変異 / 原爆被爆者 / 急性前骨髄球性白血病 / 増殖制御 / 固形がん死亡 / 骨髄不全症 / ヒト造血幹細胞 / CDC25C変異 / 健康被害 / MDS/MPN / 遺伝子ノックダウン / がん死亡危険度 / 健康影響 / 協調遺伝子変異 / 慢性骨髄単球性白血病（CMML） / KIT / 非コード性RNA / BMI-1 / 循環器疾患 / 血清飢餓 / 家族性MDS / 精神的影響 / 骨髄球系造血器腫瘍 / 放射性粉塵 / Evi1 / AML1/RUNX1遺伝子 / ベータ線被曝 / 染色体外因子 / 到達時年齢依存性 / 初期放射線 / 被曝時年齢依存性 / 転写因子 / CEBPA遺伝子 / スプライシング因子 / 受容体型チロシンキナーゼ / 多段階発がん仮説 / チロシンキナーゼ型受容体 / 放射線感受性 / BMTモデル / RUNX1遺伝子 / Microparticle effect / 医学的影響 / RUNX1遺伝子変異 / 放射性微粒子 / 急性骨髄性白血病 / 内部被曝 / 死亡危険度 / ベータ線被ばく / 骨髄性白血病 / 造血幹細胞 / 内部被ばく / マンガン56 / 疾患関連遺伝子 / 遺伝子変異 / 発がん数理モデル / 国際情報交換 / モデルマウス / 放射線被曝 / shRNA / 骨髄増殖性腫瘍 / 放射性曝露要因 / 核被害 / 黒い雨 / ノックダウン / 被ばく被害 / セミパラチンスク旧ソ連核実験場 / 数理モデル / 被ばく / 造血器悪性腫瘍 / 線量評価 / 機能性非コードRNA / ミトコンドリア機能動態 / 固形がん / 非初期放射線 / 骨髄増殖性疾患 / iPS細胞 / 被爆時年齢依存性 / BMI1 / GATA2遺伝子変異 / 放射線発がん / アンケート調査 / 放射線 / 放射線後障害 / microparticle effects / アイソタイプ / 間接被爆 Less

  • Research Projects

    (15 results)

  • Research Products

    (575 results)

  • Co-Researchers

    (68 People)

  •  Molecular mechanisms of lower-risk MDSOngoing

    • Principal Investigator
      原田 浩徳
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science

  •  若年発症家族性骨髄異形成症候群を造血幹細胞早期老化モデルとした分子発症機構の解明Principal InvestigatorOngoing

    • Principal Investigator
      原田 結花
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Bunkyo Gakuin University

  •  Overexpression of RUNX1 short isoform induced by epigenetic dysregulation in the development of myelodysplastic/myeloproliferative neoplasms (MDS/MPN)

    • Principal Investigator
      Harada Hironori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo University of Pharmacy and Life Science
      Juntendo University

  •  Study of the radiation fallout around the former Soviet Union Semipalatinsk nuclear test site - Dosimetry and health effects -

    • Principal Investigator
      HOSHI Masaharu
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Hiroshima University

  •  Molecular mechanisms of radiation-associated myelodysplastic syndromes (MDS)Principal Investigator

    • Principal Investigator
      HARADA Yuka
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Bunkyo Gakuin University
      Juntendo University

  •  Social medical study of late effect of radiation exposure on young persons

    • Principal Investigator
      OHTAKI Megu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene
    • Research Institution
      Hiroshima University

  •  The function of the novel noncoding RNA related to the growth control of myeloid leukemia cells

    • Principal Investigator
      HIRANO Tetsuo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical genome science
    • Research Institution
      Hiroshima University

  •  Molecular mechanisms of myelodysplastic syndromes (MDS) using RUNX1-mutated iPS cells derived from familial MDS patients

    • Principal Investigator
      HARADA Hironori
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Juntendo University
      Hiroshima University

  •  Research on the radiation exposure among inhabitants near the Semipalatinsk Nuclear Test Site

    • Principal Investigator
      KAWANO Noriyuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Area studies
    • Research Institution
      Hiroshima University

  •  Molecular mechanism of the therapy-related myeloid neoplasmsPrincipal Investigator

    • Principal Investigator
      HARADA Yuka
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Hiroshima University

  •  Socio-medical research about late-effects among A-bomb survivors

    • Principal Investigator
      OHTAKI Megu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene
    • Research Institution
      Hiroshima University

  •  Establishment of new classification in myeloid neoplasms for personalized medicine

    • Principal Investigator
      HARADA Hironori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Hiroshima University

  •  Human Effects in Inhabitants near the Semipalatinsk Nuclear Test Site

    • Principal Investigator
      KAWANO Noriyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Area studies
    • Research Institution
      Hiroshima University

  •  AML1 point mutations play a pivotal role in the pathogenesis of MDS/AML

    • Principal Investigator
      HARADA Hironori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Hiroshima University

  •  Genetic pathway in molecular pathogenesis of myelodysplastic syndrome (MDS) with AML1 point mutationsPrincipal Investigator

    • Principal Investigator
      HARADA Yuka
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Hiroshima University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

  • [Book] 単球増加．内科外来診断navi，富野康日己監修2017
    • Author(s)
      原田浩徳
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Book] アルキル化薬による染色体異常とMDSの発生．造血器腫瘍アトラス改訂第５版，阿部達生編2016
    • Author(s)
      原田結花　原田浩徳
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Book] 顆粒球減少症．研修ノートシリーズ「血液科研修ノート」，神田善伸責任編集2016
    • Author(s)
      原田浩徳
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Book] Epigenetic changesと白血病―CpGアイランドのメチル化やヒストン脱アセチル化．造血器腫瘍アトラス改訂第５版，阿部達生編2016
    • Author(s)
      原田結花　原田浩徳
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Book] Epigenetic changesと白血病―CpGアイランドのメチル化やヒストン脱アセチル化．造血器腫瘍アトラス改訂第５版，阿部達生編2016
    • Author(s)
      原田結花，原田浩徳
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Book] アルキル化薬による染色体異常とMDSの発生．造血器腫瘍アトラス改訂第５版，阿部達生編2016
    • Author(s)
      原田結花，原田浩徳
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Book] 顆粒球減少症．研修ノートシリーズ「血液科研修ノート」，神田善伸責任編集2016
    • Author(s)
      原田浩徳
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Book] 骨髄異形成症候群 ガイドライン外来診療20152015
    • Author(s)
      原田浩徳
    • Total Pages
      694
    • Publisher
      日経メディカル開発
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Book] 骨髄異形成症候群．ガイドライン外来診療20152015
    • Author(s)
      原田浩徳
    • Total Pages
      694
    • Publisher
      日経メディカル開発
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Book] Principles and Practice 血液・造血器・リンパ系，千葉　滋編（分担執筆，遺伝子検査）2015
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      385
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Book] 骨髄異形成症候群（MDS）の基礎と臨床　改訂版，朝長万左男編，(分担執筆，MDSの遺伝子異常スペクトラムと臨床的意義)2015
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      323
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Book] 骨髄異形成症候群．ガイドライン外来診療20152015
    • Author(s)
      原田浩徳
    • Total Pages
      694
    • Publisher
      日経メディカル開発
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Book] 骨髄異形成症候群:ガイドライン外来診療20152014
    • Author(s)
      原田浩徳
    • Total Pages
      696
    • Publisher
      日経メディカル開発
    • Data Source
      KAKENHI-PROJECT-26257501

  • [Book] 新・カラーテキスト血液病学2013
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      5
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Book] 「エピゲノム異常と発がん」, 『新・カラーテキスト血液病学(木崎昌弘編)』2013
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      687
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Book] エピゲノム異常と発がん　新・カラーテキスト血液病学（木崎昌弘編）2013
    • Author(s)
      原田結花,原田浩徳
    • Total Pages
      687
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Book] エピゲノム異常と発がん　新・カラーテキスト血液病学（木崎昌弘編）2013
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      687
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Book] エピゲノム異常と発がん　新・カラーテキスト血液病学（木崎昌弘編）2013
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      687
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Book] 造血器腫瘍とエピジェネティクス―治療への応用と新たな展開―2012
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      251
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Book] EBM血液疾患の治療2012-20132012
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      590
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Book] 造血器腫瘍とエピジェネティクス―治療への応用と新たな展開―2012
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      251
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Book] EBM血液疾患の治療2012-20132012
    • Author(s)
      原田結花，原田浩徳
    • Total Pages
      590
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Book] Molecular mechanisms that produce radiation-ihduced or therapy-related MDS/AML by RUNX1/AML1 point mutations A New Challenge of Radiation Health Risk Management(Nakashima M, Takamura N, Suzuki K, Yamashita S (Eds.))2012
    • Author(s)
      Harada H, Harada Y
    • Total Pages
      276
    • Publisher
      Nagasaki Newspaper Publish
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] A New Challenge of Radiation Health Risk Management. Nakashima M, et al, (Eds.)2012
    • Author(s)
      Harada H, Harada Y
    • Publisher
      Nagasaki Newspaper
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Book] A New Challenge ofRadiation Health Risk Molecularmechanisms that produce radiation-inducedor therapy-related MDS/ AML by RUNX1/ AML1point mutations, Management. Nakashima M, Takamura N, Suzuki K, Yamashita S(Eds.)2012
    • Author(s)
      Harada H, Harada Y
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 骨髄性白血病の発症機構.「I章.造血システムと腫瘍化」血液専門医テキスト(日本血液学会編)2011
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      556
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-21249041

  • [Book] 骨髄性白血病の発症機構.「I章.造血システムと腫瘍化」血液専門医テキスト(日本血液学会編)2011
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      556
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Book] 「治療レナリドミド」,骨髄異形成症候群(MDS)診療up-to-date(松田晃編)2011
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      183
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Book] 4.骨髄性白血病の発症機序.「I章.造血システムと腫瘍化」日本血液学会編,血液専門医テキスト2011
    • Author(s)
      原田浩徳
    • Publisher
      南光堂(印刷中)
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 骨髄性白血病の発症機構.「I章.造血システムと腫瘍化」血液専門医テキスト(日本血液学会編)2011
    • Author(s)
      原田結花、原田浩徳
    • Total Pages
      556
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Book] 骨髄性白血病の発症機構.I章.造血システムと腫瘍化」血液専門医テキスト2011
    • Author(s)
      原田結花,原田浩徳
    • Publisher
      日本血液学会編
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 「骨髄性白血病の発症機構(I章造血システムと腫瘍化)」, 血液専門医テキスト(日本血液学会編)2011
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      556
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Book] 治療レナリドミド.骨髄異形成症候群(MDS)診療up-to-date(松田晃編)2011
    • Author(s)
      原田結花、原田浩徳
    • Total Pages
      183
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Book] 治療レナリドミド.骨髄異形成症候群(MDS)診療up-to-date2011
    • Author(s)
      原田結花,原田浩徳
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 骨髄性白血病の発症機構.「I章.造血システムと腫瘍化」血液専門医テキスト(日本血液学会編)2011
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      556
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 治療レナリドミド.骨髄異形成症候群(MDS)診療up-to-date(松田晃編)2011
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      183
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Book] 治療レナリドミド.骨髄異形成症候群(MDS)診療up-to-date(松田晃編)2011
    • Author(s)
      原田結花, 原田浩徳
    • Total Pages
      183
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 血液専門医テキスト, 骨髄性白血病の発症機構.I章.造血システムと腫瘍化(日本血液学会編)2011
    • Author(s)
      原田結花,原田浩徳
    • Total Pages
      566
    • Data Source
      KAKENHI-PROJECT-21249041

  • [Book] 8.DNAメチル化阻害剤～急性骨髄性白血病に対する効果～.「血液疾患における分子標的治療 ドラッグラグ解消に向けて」I.白血病2010
    • Author(s)
      今川潤、原田浩徳
    • Total Pages
      350
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 1.レナリドミド～骨髄異形成症候群の治療～.「血液疾患における分子標的治療 ドラッグラグ解消に向けて」IV.骨髄異形成症候群2010
    • Author(s)
      原田結花、原田浩徳
    • Total Pages
      350
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Book] 1.レナリドミド～骨髄異形成症候群の治療～.「血液疾患における分子標的治療 ドラッグラグ解消に向けて」IV.骨髄異形成症候群2010
    • Author(s)
      原田結花、原田浩徳
    • Total Pages
      350
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 治療関連白血病の予後・治療法. 血液診療エキスパートvol. 1白血病2009
    • Author(s)
      原田浩徳, 他
    • Publisher
      中外医学社(印刷中)
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Book] 治療関連白血病の予後・治療法. 血液診療エキスパート vol. 1白血病2009
    • Author(s)
      原田浩徳, 原田結花
    • Total Pages
      351
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Book] 治療関連白血病の予後・治療法. 金倉譲シリーズ監修(松村到, 高橋聡, 宮崎泰司編, 血液診療エキスパートvol.1白血病. 東京)2009
    • Author(s)
      原田浩徳, 原田結花
    • Publisher
      中外医学社(印刷中)
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Book] 治療関連白血病の予後・治療法2009
    • Author(s)
      原田浩徳,原田結花
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MDS分子病態研究の進歩2017
    • Author(s)
      原田浩徳
    • Journal Title

      臨床血液

      Volume: 58 Pages: 1941-1950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Journal Article] High expression of ABCG2 induced by EZH2 disruption plays pivotal roles in MDS pathogenesis2017
    • Author(s)
      Kawabata K C、Hayashi Y、Inoue D、Meguro H、Sakurai H、Fukuyama T、Tanaka Y、Asada S、Fukushima T、Nagase R、Takeda R、Harada Y、Kitaura J、Goyama S、Harada H、Aburatani H、Kitamura T
    • Journal Title

      Leukemia

      Volume: 32 Pages: 419-428

    • DOI
      10.1038/leu.2017.227
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09831, KAKENHI-PUBLICLY-17H05634, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-15K09460

  • [Journal Article] Donor cell leukemia arising from preleukemic clones with a novel germline DDX41 mutation after allogenic hematopoietic stem cell transplantation.2017
    • Author(s)
      Kobayashi S、Kobayashi A、Osawa Y、Nagao S、Takano K、Okada Y、Tachi N、Teramoto M、Kawamura T、Horiuchi T、Kato S、Maekawa T、Yamamura T、Watanabe J、Harada Y、Harada H、Sato K、Kimura F
    • Journal Title

      Leukemia

      Volume: 31 Pages: 1020-1022

    • DOI
      10.1038/leu.2017.44
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09831, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-15K09460

  • [Journal Article] レナリドミド（低リスクMDS）［骨髄疾患による貧血：成人骨髄異形成症候群（MDS）治療］2017
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      日本臨牀増刊号「貧血学」

      Volume: 75 Pages: 262-267

    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] Myeloid neoplasms with germ line RUNX1 mutation.2017
    • Author(s)
      Hayashi Yoshihiro、Harada Yuka、Huang Gang、Harada Hironori
    • Journal Title

      Int J Hematol

      Volume: 106 Pages: 183-188

    • DOI
      10.1007/s12185-017-2258-5
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09831, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-15K09460

  • [Journal Article] MDS分子病態研究の進歩2017
    • Author(s)
      原田浩徳
    • Journal Title

      臨床血液

      Volume: 58 Pages: 1941-1950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] Overexpression of RUNX1 short isoform has an important role in the development of myelodysplastic/myeloproliferative neoplasms2017
    • Author(s)
      Sakurai Hiroko、Harada Yuka、Ogata Yosuke、Kagiyama Yuki、Shingai Naoki、Doki Noriko、Ohashi Kazuteru、Kitamura Toshio、Komatsu Norio、Harada Hironori
    • Journal Title

      Blood Advances

      Volume: 1 Pages: 1382-1386

    • DOI
      10.1182/bloodadvances.2016002725
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09831, KAKENHI-PUBLICLY-17H05634, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-15K09460

  • [Journal Article] 非5q欠失骨髄異形成症候群に対するレナリドミドの臨床効果2017
    • Author(s)
      原田結花、原田浩徳
    • Journal Title

      血液内科

      Volume: 74 Pages: 644-649

    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Journal Article] 非5q欠失骨髄異形成症候群に対するレナリドミドの臨床効果.2017
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 74 Pages: 644-649

    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] レナリドミド（低リスクMDS）［骨髄疾患による貧血：成人骨髄異形成症候群（MDS）治療］2017
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      日本臨牀増刊号「貧血学」

      Volume: 75(Suppl 1) Pages: 262-267

    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Journal Article] Understanding of MPN and MDS/MPN based on molecular pathogenesis and clinical aspects.2017
    • Author(s)
      Harada Hironori
    • Journal Title

      Int J Hematol

      Volume: 105 Pages: 709-710

    • DOI
      10.1007/s12185-017-2244-y
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09831, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-15K09460

  • [Journal Article] アルキル化剤［白血病の発症機序：抗がん剤による治療関連白血病の発症機構］2016
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      日本臨牀増刊号「白血病学（上）」

      Volume: 74 Pages: 350-354

    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] エピゲノム変異による白血病発症［白血病の発症機序］2016
    • Author(s)
      新谷直樹，原田結花，原田浩徳
    • Journal Title

      日本臨牀増刊号「白血病学（上）」

      Volume: 74(Suppl 8) Pages: 345-349

    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Journal Article] Spectrum of clinical and genetic features of patients with inherited platelet disorder with suspected predisposition to hematological malignancies: a nationwide survey in Japan2016
    • Author(s)
      Yoshimi A, Toya T, Nannya Y, Takaoka K, Kirito K, Ito E, Nakajima H, Hayashi Y, Takahashi T, Moriya-Saito A, Suzuki K, Harada H, Komatsu N, Usuki K, Ichikawa M, Kurokawa M
    • Journal Title

      Ann Oncol

      Volume: 2016 Feb 15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] アルキル化剤［白血病の発症機序：抗がん剤による治療関連白血病の発症機構］2016
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      日本臨牀増刊号「白血病学（上）」

      Volume: 74(Suppl 8) Pages: 350-354

    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Journal Article] 【骨髄増殖性腫瘍のマネジメントと最近の展開】 原発性骨髄線維症におけるオーロラキナーゼの作用機序.2016
    • Author(s)
      新谷直樹，原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 73(3) Pages: 310-5

    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Journal Article] The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition.2016
    • Author(s)
      Sashida G, Wang S, Tomioka T, Oshima M, Kazumasa Aoyama K, Kanai A, Mochizuki-Kashio M, Harada H, Shimoda K, Iwama A.
    • Journal Title

      J Exp Med.

      Volume: 213 Pages: 1459-1477

    • DOI
      10.1084/jem.20151121
    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-26461396, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-16KT0113, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-16K09831, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959

  • [Journal Article] Chronic myelomonocytic leukemia (CMML): recent advances in molecular pathogenesis and treatment2016
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      臨床血液

      Volume: 57(2) Issue: 2 Pages: 147-155

    • DOI
      10.11406/rinketsu.57.147
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-25461422

  • [Journal Article] 原発性骨髄線維症におけるオーロラキナーゼの作用機序2016
    • Author(s)
      新谷直樹，原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 73 Pages: 310-315

    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] Genetic basis of myeloid transformation in familial platelet disorder/acute　myeloid　leukemia patients with　haploinsufficient RUNX1 allele.2016
    • Author(s)
      Sakurai M, Kasahara H, Yoshida K, Yoshimi A, Kunimoto H, Watanabe N, Shiraishi Y, Chiba K, Tanaka H, Harada Y, Harada H, Kawakita T, Kurokawa M, Miyano S, Takahashi S, Ogawa S, Okamoto S, Nakajima H
    • Journal Title

      Blood Cancer J.

      Volume: 6

    • DOI
      10.1038/bcj.2015.81
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09460, KAKENHI-PUBLICLY-15H01481, KAKENHI-PROJECT-25461422, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16J07143

  • [Journal Article] エピゲノム変異による白血病発症［白血病の発症機序］2016
    • Author(s)
      新谷直樹，原田結花，原田浩徳
    • Journal Title

      日本臨牀増刊号「白血病学（上）」

      Volume: 74 Pages: 345-349

    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] del(5q)MDSに対するレナリドミドの作用機構2016
    • Author(s)
      原田結花，原田浩徳．
    • Journal Title

      血液内科

      Volume: 72 Pages: 665-670

    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Journal Article] del(5q)MDSに対するレナリドミドの作用機構2016
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 72(5) Pages: 665-670

    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Journal Article] Spectrum of clinical and genetic features of patients with inherited platelet disorder with suspected predisposition to hematological malignancies: a nationwide survey in Japan2016
    • Author(s)
      Yoshimi A, Toya T, Nannya Y, Takaoka K, Kirito K, Ito E, Nakajima H, Hayashi Y, Takahashi T, moriya-Saito A, Suzuki K, Harada H, Komatsu N, Usuki K, Ixhikawa M, Kurokawa M.
    • Journal Title

      Ann Oncol.

      Volume: 27 Pages: 887-895

    • DOI
      10.1093/annonc/mdw066
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-16K09831

  • [Journal Article] Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression2015
    • Author(s)
      Hirano Tetsuo, Yoshikawa Ryoko, Harada Hironori, Harada Yuka, Ishida Atsuhiko, Yamazaki Takeshi
    • Journal Title

      Mol Cancer

      Volume: 14 Pages: 90-104

    • DOI
      10.1186/s12943-015-0364-7
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24510277, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-25461422

  • [Journal Article] 【特集：血液内科診療の展望】　骨髄異形成症候群診療の展望2015
    • Author(s)
      原田浩徳
    • Journal Title

      日医大医会誌

      Volume: 11(4) Pages: 187-191

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] 白血病の発症機序と分子標的治療2015
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      臨床雑誌「内科」

      Volume: 116(2) Pages: 191-197

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] 【骨髄異形成症候群（MDS）－最近の進歩－】　基礎：MDSの分子病態2015
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      最新医学

      Volume: 70(11) Pages: 2069-2075

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] A C-terminal mutant of C/EBP (C/EBPa-Cm) down-regulates the Csf1r, a potent accelerator in the progression of AML with C/EBPa-Cm2015
    • Author(s)
      Togami, K., Kitaura, J., Uchida, T., Inoue, D., Nishimura, K., Kawabata, K.C., Nagase, R., Horikawa, S., Izawa, K., Fukuyama, T., Nakahara, F., Oki, T., Harada, Y., Harada, H., Aburatani, H. and Kitamura, T.
    • Journal Title

      Exp Hematol.

      Volume: 43 Pages: 300-308

    • DOI
      10.1016/j.exphem.2014.11.011
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249039, KAKENHI-PUBLICLY-25118709, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-13J09414, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-26670465

  • [Journal Article] SETBP1 mutations drive leukemic transformation in ASXL1-murtated MDS.2015
    • Author(s)
      Inoue D, Kitaura J, Matsui H, Hou HA, Chou WC, Nagamachi A, Kawabata KC, Togami K, Nagase R, Horikawa S, Saika M, Micol JB, Hayashi Y, Harada Y, Harada H, Inaba T, Tien HF, Abdel-Wahab O, Kitamura T.
    • Journal Title

      Leukemia

      Volume: 29(4) Pages: 847-57

    • DOI
      10.1038/leu.2014.301
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J09414, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-26893051, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-26670465, KAKENHI-PROJECT-26860735, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-24249039

  • [Journal Article] 【特集／骨髄異形成症候群（MDS）の病態解析と治療の進歩】　メチル化阻害薬の効果予測とゲノム解析2015
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 71(5) Pages: 593-599

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] 【特集：急性骨髄性白血病のゲノム解析～現状と展望～】 Germline変異と急性骨髄性白血病2015
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 25(11) Pages: 1607-1615

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] A randomized controlled trial comparing darbepoetin alfa doses in red blood cell transfusion-dependent patients with low- or intermediate-1 risk myelodysplastic syndromes.2015
    • Author(s)
      Jang JH, Harada H, Shibayama H, Shimazaki R, Kim HJ, Sawada K, Mitani K
    • Journal Title

      Int J Hematol

      Volume: 102(4) Pages: 401-412

    • DOI
      10.1007/s12185-015-1862-5
    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-25461449

  • [Journal Article] 9.Harada H, Harada Y. Recent advances in myelodysplastic syndromes: molecular pathogenesis and its implications for targeted therapies2015
    • Author(s)
      Harada H, Harada Y
    • Journal Title

      Cancer Sci

      Volume: 106 Pages: 329-336

    • DOI
      10.1111/cas.12614
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-26257501, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-25461422

  • [Journal Article] 【血液疾患とクローン性】 造血器腫瘍のクローン性進展　骨髄異形成症候群の病型悪化とクローン性進展2014
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 24(6) Pages: 895-902

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation.2014
    • Author(s)
      Sashida, G., Harada, H., Matsui, H., Oshima, M., Yui, M., Harada, Y., Tanaka, S., Mochizuki-Kashio, M., Wang, C., Saraya, A., Muto, T., Hayasi, Y., Suzuki, K., Nakajima, H., Inaba, T., Koseki, H., Huang, G., Kitamura, T. and Iwama, A.
    • Journal Title

      Nat Commun.

      Volume: 5 Pages: 4177-4177

    • DOI
      10.1038/ncomms5177
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24249054, KAKENHI-PROJECT-24591397, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PUBLICLY-25130702, KAKENHI-PROJECT-25461422, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-26257501, KAKENHI-PROJECT-26461396, KAKENHI-PROJECT-26461460

  • [Journal Article] 【赤血球造血と疾患をめぐる最近の進歩】 MDSに対する薬物療法の進歩2014
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 68(5) Pages: 616-623

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] 【血液疾患とクローン性】 造血器腫瘍のクローン性進展　骨髄異形成症候群の病型悪化とクローン性進展2014
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 24(6) Pages: 895-902

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] 骨髄異形成症候群におけるRUNX1変異とBMI1過剰発現の協調作用2014
    • Author(s)
      原田結花，北村俊雄，原田浩徳
    • Journal Title

      血液内科

      Volume: 68 Pages: 805-813

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP9 up-regulation in leukemic cells.2014
    • Author(s)
      Nakahara F, Kitaura J, Uchida T, Nishida C, Togami K, Inoue D, Matsukawa T, Kagiyama Y, Enomoto Y, Kawabata KC, Chen-Yi L, Komeno Y, Izawa K, Oki T, Nagae G, Harada Y, Harada H, Otsu M, Aburatani H, Heissig B, Hattori K, Kitamura T.
    • Journal Title

      blood

      Volume: 123(25) Pages: 3932-3942

    • DOI
      10.1182/blood-2013-01-476747
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J09414, KAKENHI-PLANNED-22112007, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24591382, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-25860521, KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-26461415

  • [Journal Article] 【赤血球造血と疾患をめぐる最近の進歩】 MDSに対する薬物療法の進歩2014
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 68(5) Pages: 805-813

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] 骨髄系造血器腫瘍発症の分子機構2014
    • Author(s)
      北村俊雄，井上大地，中原史雄，大河内直子，加藤菜穂子，戸上勝仁，内田智之，鍵山侑希，川畑公人，永瀬玲奈，堀川小百合，林 康貴，齋賀真言，伊沢久未，沖 俊彦，千葉 滋，原田結花，原田浩徳，北浦次郎
    • Journal Title

      臨床血液

      Volume: 55(10) Pages: 1715-1723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] Molecular basis of hematological malignancies2014
    • Author(s)
      北村俊雄，井上大地，中原史雄，大河内直子，加藤菜穂子，戸上勝仁，内田智之，鍵山侑希，川畑公人，永瀬玲奈，堀川小百合，林 康貴，齋賀真言，伊沢久未，沖 俊彦，千葉 滋，原田結花，原田浩徳，北浦次郎
    • Journal Title

      臨床血液

      Volume: 55 Issue: 10 Pages: 1715-1723

    • DOI
      10.11406/rinketsu.55.1715
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis2014
    • Author(s)
      Uchida T, Kawabata KC, Kitamura T., et al.
    • Journal Title

      Experimental hematology

      Volume: S0301-472X(14) Pages: 56-3

    • DOI
      10.1016/j.exphem.2014.01.009
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J09414, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422

  • [Journal Article] Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.2014
    • Author(s)
      Lam K, Muselman A, Du R, Harada Y, Scholl AG, Yan M, Matsuura S, Weng S, Harada H, Zhang DE
    • Journal Title

      Blood

      Volume: 124 Pages: 2203-2212

    • DOI
      10.1182/blood-2014-02-554543
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-26257501

  • [Journal Article] 広島で近距離被爆後に長期間を経て白血病を発症した母娘例2014
    • Author(s)
      岡田浩佑，鎌田七男，藤村欣吾，河村 寛，中井志郎，田中公夫，小熊信夫，許 泰一，岩戸康司，板垣充弘，宮原弥恵，新谷貴洋，原田浩徳，佐々木英夫
    • Journal Title

      広島医学

      Volume: 67 Pages: 396-400

    • Data Source
      KAKENHI-PROJECT-26257501

  • [Journal Article] Recurrent CDC25C mutations drive malignant transformation in FPD/AML.2014
    • Author(s)
      Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, Nakagawa M, Nannya Y, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Ichikawa M, Mano H, Kurokawa M
    • Journal Title

      Nature Communications

      Volume: 5 Pages: 4770-4770

    • DOI
      10.1038/ncomms5770
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24390268, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670482, KAKENHI-PROJECT-25830139, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-26461598, KAKENHI-PROJECT-26860474

  • [Journal Article] Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients. Leukemia,2014
    • Author(s)
      Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Yuasa S, Yamazaki S, Nishimura T, Sadahira K, Fukuda K, Okano H, Nakauchi H, Morita Y, Matsumura I, Kudo K, Ito E, Ebihara Y, Tsuji K, Harada Y, Harada H, Okamoto S, Nakajima H
    • Journal Title

      Leukemia.

      Volume: 28 Pages: 2344-2354

    • DOI
      10.1038/leu.2014.136
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390272, KAKENHI-PROJECT-24591398, KAKENHI-PROJECT-24659467, KAKENHI-PUBLICLY-25118716, KAKENHI-PUBLICLY-25130712, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-25461439, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-26257501, KAKENHI-PROJECT-26293243, KAKENHI-PROJECT-26670511

  • [Journal Article] ばく関連資料データベース(新聞記事)のテキスト解析の試み2014
    • Author(s)
      佐藤裕哉，佐藤健一，原田結花，嶋本浩子，原憲行，原田浩徳，大瀧 慈，田代 聡
    • Journal Title

      広島医学

      Volume: 67(4) Pages: 406-409

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] 骨髄系造血器腫瘍発症の分子機構2014
    • Author(s)
      北村俊雄，井上大地，中原史雄，大河内直子，加藤菜穂子，戸上勝仁，内田智之，鍵山侑希，川畑公人，永瀬玲奈，堀川小百合，林 康貴，齋賀真言，伊沢久未，沖 俊彦，千葉 滋，原田結花，原田浩徳，北浦次郎
    • Journal Title

      臨床血液

      Volume: 55(10) Pages: 1715-1723

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] 【赤血球造血と疾患をめぐる最近の進歩】 MDSに対する薬物療法の進歩2014
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 68 Pages: 616-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] 【血液疾患とクローン性】 造血器腫瘍のクローン性進展　骨髄異形成症候群の病型悪化とクローン性進展2014
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 24 Pages: 895-902

    • Data Source
      KAKENHI-PROJECT-26257501

  • [Journal Article] 広島原爆入市被曝者の移動経路の分析2014
    • Author(s)
      佐藤裕哉, 佐藤健一, 原 憲行, 布施博之, 原田結花
    • Journal Title

      長崎医学会雑誌

      Volume: 89 Pages: 240-243

    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] 広島原爆入市被曝者の移動経路の分析2014
    • Author(s)
      佐藤裕哉，佐藤健一，原　憲行，布施博之，原田結花
    • Journal Title

      長崎医学会雑誌

      Volume: 89 Pages: 240-243

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] 骨髄異形成症候群におけるRUNX1変異とBMI1過剰発現の協調作用2014
    • Author(s)
      8.原田結花，北村俊雄，原田浩徳
    • Journal Title

      血液内科

      Volume: 68 Pages: 805-813

    • Data Source
      KAKENHI-PROJECT-26257501

  • [Journal Article] 広島で近距離被爆後に長期間を経て白血病を発症した母娘例2014
    • Author(s)
      岡田浩佑，鎌田七男，藤村欣吾，河村 寛，中井志郎，田中公夫，小熊信夫，許 泰一，岩戸康司，板垣充弘，宮原弥恵，新谷貴洋，原田浩徳，佐々木英夫
    • Journal Title

      広島医学

      Volume: 67 Pages: 396-400

    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] 骨髄異形成症候群におけるRUNX1変異とBMI1過剰発現の協調作用2014
    • Author(s)
      原田結花，北村俊雄，原田浩徳
    • Journal Title

      血液内科

      Volume: 68(6) Pages: 805-813

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] 原爆・被ばく関連資料データベース(新聞記事)のテキスト解析の試み2014
    • Author(s)
      佐藤裕哉，佐藤 健，原田結花，嶋本浩子，原憲行，原田浩徳，大瀧 慈，田代 聡
    • Journal Title

      広島医学

      Volume: 67 Pages: 406-409

    • Data Source
      KAKENHI-PROJECT-26257501

  • [Journal Article] 原爆・被ばく関連資料データベース（新聞記事）のテキスト解析の試み2014
    • Author(s)
      佐藤裕哉, 佐藤健一, 原田結花, 嶋本浩子, 原 憲行, 原田浩徳, 大瀧 慈, 田代 聡
    • Journal Title

      広島医学

      Volume: 67 Pages: 406-409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] 【血液疾患とクローン性】 造血器腫瘍のクローン性進展　骨髄異形成症候群の病型悪化とクローン性進展2014
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 24 Pages: 895-902

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] 広島で近距離被爆後に長期間を経て白血病を発症した母娘例2014
    • Author(s)
      岡田浩佑，鎌田七男，藤村欣吾，河村 寛，中井志郎，田中公夫，小熊信夫，許 泰一，岩戸康司，板垣充弘，宮原弥恵，新谷貴洋，原田浩徳，佐々木英夫
    • Journal Title

      広島医学

      Volume: 67(4) Pages: 396-400

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes2013
    • Author(s)
      Harada Y, Inoue D, Ding Y, Imagawa J, Doki N, Matsui H, Yahata T, Matsushita H, Ando K, Sashida G, Iwama A, Kitamura T, Harada H
    • Journal Title

      Blood

      Volume: 121 Pages: 3434-3446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] 急性前骨髄球性白血病．特集：臨床血液学　今後の展望（2013年版）―骨髄系疾患―2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      臨床血液

      Volume: 54 Pages: 49-60

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] CMML発症のゲノム異常2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 67 Pages: 305-312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] 原田結花，原田浩徳 低リスクMDSに対するレナリドミド2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 67(3) Pages: 305-312

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] Myelodysplastic syndromes are induced by histone methylation-altering ASXL1 mutations2013
    • Author(s)
      Inoue D, Kitaura J, Togami K, Nishimura K, Enomoto Y, Uchida T, Kagiyama Y, Kawabata KC, Nakahara F, Izawa K, Oki T, Maehara A, Isobe M, Tsuchiya A, Harada Y, Harada H, Ochiya T, Aburatani H, Kimura H, Thol F, Heuser M, Levine RL, Abdel-Wahab O, Kitamura T
    • Journal Title

      J Clin Invest

      Volume: 123 Pages: 4627-4640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] MDSに対するメチル化阻害剤による治療の現状と展望2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 66(3) Pages: 316-322

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes2013
    • Author(s)
      Harada Y, Inoue D, Ding Y, Imagawa J, Doki N, Matsui H, Yahata T, Matsushita H, Ando K, Sashida G, Iwama A, Kitamura T, Harada H
    • Journal Title

      Blood

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDSに対するメチル化阻害剤による治療の現状と展望2013
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液内科

      Volume: 66(3)巻 Pages: 316-322

    • Data Source
      KAKENHI-PROJECT-23310183

  • [Journal Article] MDSに対するメチル化阻害剤による治療の現状と展望2013
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液内科

      Volume: 66(3) Pages: 316-322

    • Data Source
      KAKENHI-PROJECT-23310183

  • [Journal Article] CMML発症のゲノム異常2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 67(5) Pages: 631-637

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] 急性前骨髄球性白血病．特集：臨床血液学　今後の展望（2013年版）―骨髄系疾患―2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      臨床血液

      Volume: 54 Pages: 49-60

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDSに対するメチル化阻害剤による治療の現状と展望2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 66(3) Pages: 316-322

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] Myelodysplastic syndromes are induced by histone methylation-altering ASXL1 mutations2013
    • Author(s)
      Inoue, D
    • Journal Title

      J Clin Invest.

      Volume: 123 Pages: 4627-40

    • DOI
      10.1172/jci70739
    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23310183, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422

  • [Journal Article] 低リスクMDSに対するレナリドミド2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 67(3) Pages: 305-312

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] MDS に対するメチル化阻害剤による治療の現状と展望2013
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      液内科

      Volume: 66(3) Pages: 316-322

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] 低リスクMDSに対するレナリドミド2013
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液内科

      Volume: 67(3) Pages: 305-312

    • Data Source
      KAKENHI-PROJECT-23310183

  • [Journal Article] High early death rate in elderly patients with acute promyelocytic leukemia treated with all-trans retinoic acid combined chemotherapy2013
    • Author(s)
      Imagawa J, Harada Y, Shimomura T, Tanaka H, Okikawa Y, Harada H
    • Journal Title

      Int J Hematol

      Volume: 98 Pages: 264-266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Journal Article] High early death rate in elderly patients with acute promyelocytic leukemia treated with all-trans retinoic acid combined chemotherapy2013
    • Author(s)
      Imagawa J, Harada Y, Shimomura T, Tanaka H, Okikawa Y, Harada H
    • Journal Title

      Int J Hematol

      Volume: vol. 98(2) Pages: 264-266

    • DOI
      10.1007/s12185-013-1390-0
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310183, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422

  • [Journal Article] CMML発症のゲノム異常2013
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液内科

      Volume: 67(5) Pages: 631-637

    • Data Source
      KAKENHI-PROJECT-23310183

  • [Journal Article] 急性前骨髄球性白血病.特集:臨床血液学 今後の展望(2013 年版)-骨髄系疾患-2013
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      臨床血液

      Volume: 54(1) Pages: 49-60

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] CMML発症のゲノム異常2013
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 67(5) Pages: 631-637

    • Data Source
      KAKENHI-PROJECT-25461422

  • [Journal Article] RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes.2013
    • Author(s)
      原田結花、井上大地, 他
    • Journal Title

      Blood

      Volume: 128(3) Pages: 3434-3436

    • DOI
      10.1182/blood-2012-06-434423
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04145, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23310183, KAKENHI-PROJECT-24590361, KAKENHI-PROJECT-24591397, KAKENHI-PROJECT-24591398, KAKENHI-PROJECT-24591411, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422

  • [Journal Article] Expansion of CD8+/ perforin+ T-cells predicts response to ciclosporinA therapy in patients with erythroidhypoplasia/ aplasia2012
    • Author(s)
      Nitta H, Harada Y, Hyodo H, Kimura A, Harada H
    • Journal Title

      Brit. J. Haemtol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249041

  • [Journal Article] 骨髄異形成症候群(MDS)と慢性骨髄性白血病(CML)における白血病移行の分子機構.第73回日本血液学会学術集会シンポジウム 112012
    • Author(s)
      北村俊雄,大河内直子,井上大地,戸上勝仁,内田智之,鍵山侑希,川畑公人,千葉 滋,原田結花,原田浩徳,北浦次郎,中原史雄
    • Journal Title

      臨床血液

      Volume: 53(8) Pages: 734-739

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] A sharp fluctuation in peripheral blood cells shortly after dasatinib administration2012
    • Author(s)
      Imagawa J, Tanaka H, Matsumoto K, Morita K, Harada Y, Harada H
    • Journal Title

      Int J Hematol

      Volume: 96(2) Pages: 194-199

    • DOI
      10.1007/s12185-012-1138-2
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-23310183, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-23118518

  • [Journal Article] 治療関連白血病の病因・病態と治療2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      日本臨牀

      Volume: 70 Pages: 699-703

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] 放射線発がん(骨髄異形成症候群・白血病)の分子病態,特集「放射線の人体影響～原爆・チェルノブイリの知見とフクシマ」2012
    • Author(s)
      Nitta H, Harada Y, Hyodo H, Kimura A, Harada H
    • Journal Title

      血液フロンティア

      Volume: (in press) Pages: 1775-1781

    • DOI
      10.1111/j.1365-2141.2012.09057.x
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249041, KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-23310183, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-23118518

  • [Journal Article] Morphologic analysis in myelodysplastic syndromes with del(5q) treated with lenalidomide. A2012
    • Author(s)
      Matsuda A, Taniwaki M, Jinnai I, Harada H, Watanabe M, Suzuki K, Yanagita S, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Tohyama K, Takatoku M, Ozawa K
    • Journal Title

      LeukRes.

      Volume: (in press) Pages: 575-580

    • DOI
      10.1016/j.leukres.2011.11.011
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-23590696, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-23118518

  • [Journal Article] 骨髄異形成症候群（MDS）と慢性骨髄性白血病（CML）における白血病移行の分子機構2012
    • Author(s)
      北村俊雄，大河内直子，井上大地，戸上勝仁，内田智之，鍵山侑希，川畑公人，千葉　滋，原田結花，原田浩徳，北浦次郎，中原史雄
    • Journal Title

      臨床血液

      Volume: 53 Pages: 734-739

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] RUNX1異常によるAML2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      最新医学

      Volume: 67 Pages: 2433-2439

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] 造血器腫瘍におけるEZH2変異とその機能的意義[特集:造血器腫瘍の新たな分子病態とその臨床的意義]2012
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液内科

      Volume: 64(2) Pages: 139-144

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MDSにおける遺伝子変異の臨床的意義［特集：造血不全症］2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 64 Pages: 551-556

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDS における遺伝子変異の臨床的意義[特集:造血不全症]2012
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液内科

      Volume: 64(5) Pages: 551-556

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDSにおける遺伝子変異の臨床的意義［特集：造血不全症］2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 64 Pages: 551-556

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] Fynis not essential for Bcr-Abl-induced leukemogenesis in mouse bone marrow transplantation models2012
    • Author(s)
      Doki N, Kitaura J, Inoue D, Kato N, Kagiyama Y, Uchida T, Togami K, Isobe M, Ito S, Maehara A, Izawa K, Oki T, HaradaY, Nakahara F, Harada H, Kitamura T
    • Journal Title

      Int J Hematol

      Volume: 95(2) Pages: 167-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Fyn is not essential for Bcr-Abl-induced leukemogenesis in mouse bone marrow transplantation models.2012
    • Author(s)
      Doki N, Kitaura J, Inoue D, Kato N, Kagiyama Y, Uchida T, Togami K, Isobe M, Ito S, Maehara A, Izawa K, Oki T, Harada Y, Nakahara F, Harada H, Kitamura T
    • Journal Title

      Int. J. Hematol.

      Volume: 95(2) Pages: 167-175

    • DOI
      10.1007/s12185-011-0994-5
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22591038, KAKENHI-PUBLICLY-23118518, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23791074, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002

  • [Journal Article] MDSの分子病態［特集：MDSをめぐる最近の進歩―治癒を目指して］2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 65 Pages: 300-307

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Molecular mechanisms that produce radiation-induced or therapy-related MDS/AML by RUNX1/AML1 point mutations2012
    • Author(s)
      Harada H, Harada Y
    • Journal Title

      Acta Medica Nagasakiensia

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDS の分子病態[特集:MDS をめぐる最近の進歩-治癒を目指して]2012
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液内科

      Volume: 65(3) Pages: 300-307

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] C-terminal mutation of RUNX1 attenuates the DNA-damage repairresponse in hematopoietic stem cells.2012
    • Author(s)
      Satoh Y, Matsumura I, Tanaka H, HaradaH, Harada Y, Matsui K, Shibata M, MizukiM, Kanakura Y
    • Journal Title

      Leukemia

      Volume: 26(2) Pages: 303-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] 造血器腫瘍における EZH2 変異とその機能的意義[特集:造血器腫瘍の新たな分子病態とその臨床的意義]2012
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液内科

      Volume: 64(2) Pages: 139-144

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDSの分子病態［特集：MDSをめぐる最近の進歩―治癒を目指して］2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      血液内科

      Volume: 65 Pages: 300-307

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] RUNX1異常によるAML．特集：急性骨髄性白血病：分子異常と予後2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      最新医学

      Volume: 67 Pages: 2433-2439

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] 治療関連白血病の病因・病態と治療2012
    • Author(s)
      原田結花，原田浩徳
    • Journal Title

      日本臨牀

      Volume: 70 Pages: 699-703

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] RUNX1 異常によるAML.特集:急性骨髄性白血病:分子異常と予後2012
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      最新医学

      Volume: 67(10) Pages: 2433-2439

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] C-terminal mutation of RUNX1 attenuates the DNA- damage repair response in hematopoietic stem cells2012
    • Author(s)
      Satoh Y, Mizuki M, Kanakura Y, et al
    • Journal Title

      Leukemia

      Volume: 26(2) Pages: 303-311

    • DOI
      10.1038/leu.2011.202
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591202, KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22390194, KAKENHI-PROJECT-22591034, KAKENHI-PROJECT-22591036, KAKENHI-PROJECT-22591038, KAKENHI-PUBLICLY-23118518, KAKENHI-PROJECT-23310183, KAKENHI-PROJECT-23591385, KAKENHI-PROJECT-23591387, KAKENHI-PROJECT-23659488, KAKENHI-PROJECT-22659180, KAKENHI-PUBLICLY-23130513

  • [Journal Article] 治療関連白血病の病因・病態と治療.造血器腫瘍学-基礎と臨床の最新研究動向-第2版2012
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      金倉 譲編.日本臨牀

      Volume: 70(suppl 2) Pages: 699-703

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Morphologic analysis in myelodysplastic syndromes with del(5q) treated with lenalidomide2012
    • Author(s)
      Matsuda A, Taniwaki M, Jinnai I, HaradaH, Watanabe M, Suzuki K, Yanagita S, SuzukiT, Yoshida Y, Kimura A, Tsudo M, TohyamaK, Takatoku M, Ozawa K
    • Journal Title

      A Japanese multi-institutional study. LeukRes

      Volume: 36(5) Pages: 575-580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Molecular mechanisms that produce radiation-induced or therapy-related MDS/AML by RUNX1/AML1 point mutations2012
    • Author(s)
      Harada H, Harada Y
    • Journal Title

      Acta Medica Nagasakiensia

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Journal Article] 骨髄異形成症候群（MDS）と慢性骨髄性白血病（CML）における白血病移行の分子機構2012
    • Author(s)
      北村俊雄，大河内直子，井上大地，戸上勝仁，内田智之，鍵山侑希，川畑公人，千葉　滋，原田結花，原田浩徳，北浦次郎，中原史雄
    • Journal Title

      臨床血液

      Volume: 53 Pages: 734-739

    • Data Source
      KAKENHI-PROJECT-24591398

  • [Journal Article] Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell2012
    • Author(s)
      Oki T, Kitaura J, Watanabe-Okochi N, Nishimura K, Maehara A, Uchida T, Komeno Y, Nakahara F, Harada Y, Sonoki T, Harada H, Kitamura T
    • Journal Title

      Leukemia

      Volume: (in press) Pages: 1038-1045

    • DOI
      10.1038/leu.2011.328
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23791074, KAKENHI-PROJECT-24591398, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PUBLICLY-23118518

  • [Journal Article] [解説]APL治療後の二次性骨髄性腫瘍とその特徴2011
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液内科

      Volume: 63 Pages: 382-388

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Good' ssyndrome-associated pure red cell aplasia with myelodysplastic syndrome2011
    • Author(s)
      Nitta H, Harada Y, Okikawa Y, Fujii M, Arihiro K, Kimura A, Harada
    • Journal Title

      Intern Med

      Volume: 50(18) Pages: 2011-2014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis : lessons from clinical data and BMT models2011
    • Author(s)
      Kato N, Harada Y, Harada H, et al.
    • Journal Title

      Blood

      Volume: 117(1) Pages: 221-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] メチル化阻害剤の作用機構.特集「注目されるDNAメチル化と脱メチル化剤～骨髄異形成症候群(MDS)を中心に～2011
    • Author(s)
      原田結花, 今川潤, 原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 21 Pages: 1291-1298

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Good's Syndrome-Associated Pure Red Cell Aplasia with Myelodysplastic Syndrome2011
    • Author(s)
      Nitta H, Harada Y, Okikawa Y, Fujii M, Arihiro K, Kimura A, Harada H
    • Journal Title

      Intern Med

      Volume: 50 Issue: 18 Pages: 2011-2014

    • DOI
      10.2169/internalmedicine.50.5709
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249041, KAKENHI-PROJECT-22591038, KAKENHI-PUBLICLY-23118518, KAKENHI-PROJECT-23310183

  • [Journal Article] MDS「分子病態」2011
    • Author(s)
      原田浩徳
    • Journal Title

      第73回日本血液学会学術集会教育講演特集号.臨床血液

      Volume: 52 Pages: 1525-1534

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] メチル化阻害剤の作用機構2011
    • Author(s)
      原田結花,今川 潤,原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 21(9) Pages: 1291-1298

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Molecular mechanisms that produce secondary MDS/AML by RUNX1/AML1 Point Mutations2011
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: 112(2) Pages: 425-432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] ダサチニブ少量療法が有効であったイマチニブ不耐容慢性好酸球性白血病2011
    • Author(s)
      今川潤, 原田結花, 吉田徹巳, 樽谷美保, 木村昭郎, 松元加奈, 森田邦彦, 原田浩徳
    • Journal Title

      臨床血液

      Volume: 52(7) Pages: 546-550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] APL治療後の二次性骨髄性腫瘍とその特徴2011
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液内科

      Volume: 63(3) Pages: 382-388

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MPNと遺伝2011
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      最新医学

      Volume: 66(11) Pages: 2552-2557

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] APL治療後の二次性骨髄性腫瘍とその特徴2011
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液内科

      Volume: 63(3) Pages: 382-388

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] [解説]APL 治療後の二次性骨髄性腫瘍とその特徴2011
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液内科

      Volume: 63(3) Pages: 382-288

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Molecular mechanisms that produce secondary MDS/AML by RUNX1/AML1 point mutations2011
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      J Cell Biochem

      Volume: 112(2) Pages: 425-432

    • DOI
      10.1002/jcb.22974
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] ダサチニブ少量療法が有効であったイマチニブ不耐容慢性好酸球性白血病2011
    • Author(s)
      今川潤, 原田結花, 吉田徹巳, 樽谷美保, 木村昭郎, 松元加奈, 森田邦彦, 原田浩徳
    • Journal Title

      臨床血液

      Volume: 52(7) Pages: 546-550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Molecular mechanisms that produce secondary MDS/AML by RUNX1/AML1 Point Mutations2011
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: 112 Pages: 425-432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249041

  • [Journal Article] Two types of C/EBP mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models2011
    • Author(s)
      Kato, N
    • Journal Title

      Blood

      Volume: 117 Pages: 221-233

    • DOI
      10.1182/blood-2010-02-270181
    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-23249051

  • [Journal Article] 放射線発がん(骨髄異形成症候群・白血病)の分子病態.特集「放射線の人体影響～原爆・チェルノブイリの知見とフクシマ～」.2011
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 21(12) Pages: 1775-1781

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MDS「分子病態」2011
    • Author(s)
      原田浩徳
    • Journal Title

      臨床血液

      Volume: 52(10) Pages: 1525-1534

    • Data Source
      KAKENHI-PROJECT-23310183

  • [Journal Article] Two typesof C/ EBP mutations play distinct but collaborative roles in leukemogenesis2011
    • Author(s)
      Kato N, Kitaura J, Doki N, Komeno Y, Watanabe-Okochi N, Togami K, Nakahara F, Oki T, Enomoto Y, Fukuchi Y, Nakajima H, Harada Y, Harada H, Kitamura T
    • Journal Title

      lessons from clinical data and BMT models. Blood

      Volume: 117 Pages: 221-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MPNと遺伝2011
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      最新医学

      Volume: 66(11) Pages: 2552-2557

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] 放射線発がん(骨髄異形成症候群・白血病)の分子病態2011
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      特集「放射線の人体影響～原爆・チェルノブイリの知見とフクシマ～」.血液フロンティア

      Volume: 21(12) Pages: 1775-1781

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Molecular mechanisms that produce secondary MDS/AML by RUNX1/AML1 Point Mutations2011
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: 112(2) Pages: 425-432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MPN と遺伝.特集:骨髄増殖性腫瘍(MPN)の最新の進歩2011
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      最新医学

      Volume: 66(11) Pages: 2552-2557

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] 12.原田結花,今川潤,原田浩徳:メチル化阻害剤の作用機構2011
    • Author(s)
      原田結花, 今川潤, 原田浩徳
    • Journal Title

      血液フロンティア

      Volume: 21 Pages: 1291-1298

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Good's syndrome-associated pure red cell aplasia with myelodysplastic syndrome2011
    • Author(s)
      Nitta H, Harada Y, Okikawa Y, Fujii M, Arihiro K, Kimura A, Harada H
    • Journal Title

      Intern Med

      Volume: 50 Pages: 2011-2014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MDS「分子病態」.第73回日本血液学会学術集会教育講演特集号2011
    • Author(s)
      原田浩徳
    • Journal Title

      臨床血液

      Volume: 52(10) Pages: 1525-1534

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MPNと遺伝.特集2011
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      骨髄増殖性腫瘍(MPN)の最新の進歩.最新医学

      Volume: 66(11) Pages: 2552-2557

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Mole cularmechanisms that produce secondaryMDS/ AML by RUNX1/ AML1 pointmutations2011
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      J Cell Biochem

      Volume: 112 Pages: 425-432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249041

  • [Journal Article] Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis : lessons from clinical data and BMT models2011
    • Author(s)
      Kato N, Harada Y, Harada H, et al.
    • Journal Title

      Blood

      Volume: 117(1) Pages: 221-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Molecularmechanisms that produce secondary MDS/ AMLby RUNX1/ AML1 point mutations2011
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      J Cell Biochem

      Volume: 112 Pages: 425-432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MDS「分子病態」2011
    • Author(s)
      原田浩徳
    • Journal Title

      臨床血液

      Volume: 52(10) Pages: 1525-1534

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] 骨髄増殖性腫瘍における白血病移行の分子機構.[特集 骨髄増殖性腫瘍をめぐる最近の進歩]2010
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61(2) Pages: 143-150

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] TET2と骨髄性腫瘍.2010
    • Author(s)
      原田浩徳, 原田結花
    • Journal Title

      TET2と骨髄性腫瘍

      Volume: 20 Pages: 1902-1906

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] C/ EBPα変異パターンによる急性骨髄性白血病(AML)および骨髄異形成症候群(MDS)病型の解析.2010
    • Author(s)
      原田浩徳, 今川潤, 原田結花, 木村昭郎
    • Journal Title

      広島医学

      Volume: 63(4) Pages: 311-313

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Hes1 immortalizes committed progenitors and plays a role in blast crisis transitionin chronic myelogenous leukemia2010
    • Author(s)
      Nakahara F, Sakata-Yanagimoto M, Komeno Y, Kato N, Uchida T, Haraguchi K, Kumano K, Harada Y, Harada H, Kitaura J, Ogawa S, Kurokawa M, Kitamura T, Chiba S
    • Journal Title

      Blood

      Volume: 115(14) Pages: 2872-2881

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia2010
    • Author(s)
      Nakahara F, Harada Y, Harada H, et al.
    • Journal Title

      Blood

      Volume: 115(14) Pages: 2872-2881

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] C/EBPα変異パターンによる急性骨髄性白血病(AML)および骨髄異形成症候群(MDS)病型の解析2010
    • Author(s)
      原田浩徳, 今川潤, 原田結花, 木村昭郎
    • Journal Title

      広島医学

      Volume: 63(4) Pages: 311-313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] 骨髄増殖性腫瘍における白血病移行の分子機構2010
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61 Pages: 143-150

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] AID-inducedT-lymphoma or B-leukemia/ lymphoma in amouse BMT model.2010
    • Author(s)
      Komeno Y, Kitaura J, Watanabe-OkochiN, Kato N, Oki T, Nakahara F, Harada Y, Harada H, Shinkura R, Nagaoka H, HayashiY, Honjo T, Kitamura T
    • Journal Title

      Leukemia

      Volume: 24(5) Pages: 1018-1024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia2010
    • Author(s)
      Nakahara F, Harada Y, Harada H, Chiba S
    • Journal Title

      Blood

      Volume: 115(14) Pages: 2872-2881

    • DOI
      10.1182/blood-2009-05-222836
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Clinical and genetic features of therapy-related myeloid neoplasms after chemotherapy for acute promyelocytic leukemia2010
    • Author(s)
      Imagawa J, Harada Y, Shimomura T, Tanaka H, Okikawa Y, Hyodo H, Kimura A, Harada H
    • Journal Title

      Blood

      Volume: 116(26) Pages: 6018-6022

    • DOI
      10.1182/blood-2010-06-289389
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Clinical and genetic features of therapy-related myeloid neoplasms after chemotherapy for acute promyelocytic leukemia.2010
    • Author(s)
      Imagawa J, Harada Y, Harada H, 他
    • Journal Title

      Blood, prepublished online September 22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] Giant granulocytic sarcoma of the vagina concurrent with acute myeloid leukemia with t(8;21)(922;922) translocation2010
    • Author(s)
      Imagawa J, Harada Y, Harada H, et al.
    • Journal Title

      International Journal of Hematology

      Volume: 92(3) Pages: 553-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] DNAメチル化阻害剤～急性骨髄性白血病に対する効果～.別冊血液フロンティア「血液疾患における分子標的治療ドラッグラグ解消に向けて」I.白血病.2010
    • Author(s)
      今川潤, 原田浩徳
    • Journal Title

      企画:黒川峰夫.大阪,医薬ジャーナル社

      Pages: 1513-1519

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] 骨髄増殖性腫瘍における白血病移行の分子機構2010
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61 Pages: 143-150

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model2010
    • Author(s)
      Komeno Y, Harada Y, Harada H, et al
    • Journal Title

      Leukemia

      Volume: 24(5) Pages: 1018-1024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDS に対するレナリドミド治療とその感受性因子2010
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61 Pages: 690-698

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia2010
    • Author(s)
      Nakahara F, Harada Y, Harada H, et al.
    • Journal Title

      Blood (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MDSに対するレナリドミド治療とその感受性因子.[特集 骨髄異形成症候群(MDS)-病態の解明と克服に向けた進歩2010
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61(6) Pages: 690-698

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] レナリドミド~骨髄異形成症候群の治療~.別冊血液フロンティア「血液疾患における分子標的治療ドラッグラグ解消に向けて」IV.骨髄異形成症候群2010
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      企画:大屋敷一馬.大阪,医薬ジャーナル社

      Pages: 1733-1740

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] 骨髄増殖性腫瘍における白血病移行の分子機構.[特集 骨髄増殖性腫瘍をめぐる最近の進歩]2010
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61(2) Pages: 143-150

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model2010
    • Author(s)
      Komeno Y, Harada Y, Harada H, et al
    • Journal Title

      Leukemia

      Volume: 24(5) Pages: 1018-1024

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] レナリドミド～骨髄異形成症候群の治療～2010
    • Author(s)
      原田結花,原田浩徳
    • Journal Title

      血液フロンティア 2010 年別冊

      Volume: 20(S-1) Pages: 1733-1740

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] AID- induced T-lymphoma or B-leukemia/ lymphoma in a mouse BMT model2010
    • Author(s)
      Komeno Y, Kitaura J, Watanabe-Okochi N, Kato N, Oki T, Nakahara F, Harada Y, Harada H, Shinkura R, Nagaoka H, Hayashi Y, Honjo T, Kitamura T.
    • Journal Title

      Leukemia

      Volume: 24 Pages: 1018-1024

    • DOI
      10.1038/leu.2010.40
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390316, KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196

  • [Journal Article] DNA メチル化阻害剤～急性骨髄性白血病に対する効果～.2010
    • Author(s)
      今川 潤,原田浩徳
    • Journal Title

      血液フロンティア 2010 年別冊

      Volume: 20(S-1) Pages: 1513-1519

    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] MDSに対するレナリドミド治療とその感受性因子.[特集 骨髄異形成症候群(MDS)-病態の解明と克服に向けた進歩2010
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61(6) Pages: 690-698

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] MDSに対するレナリドミド治療とその感受性因子2010
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 61 Pages: 690-698

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Clinical and genetic features oftherapy-related myeloid neoplasms after chemotherapy for acute promyelocytic leukemia.2010
    • Author(s)
      Imagawa J, Harada Y, Shimomura T, Tanaka H, Okikawa Y, Hyodo H, Kimura A, Harada H
    • Journal Title

      Blood

      Volume: 116 Pages: 6018-6022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis : lessons from clinical data and BMT models.2010
    • Author(s)
      Kato N, Harada Y, Harada H, 他
    • Journal Title

      Blood, prepublished online September 30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] Giant granulocytic sarcoma of the vagina concurrent with acute myeloid leukemiawith t(8 ; 21)(q22 ; q22) translocation.2010
    • Author(s)
      Imagawa J, Harada Y, Yoshida T, SakaiA, Sasaki N, Kimura A, Harada H
    • Journal Title

      Int J Hematol

      Volume: 92(3) Pages: 553-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Clinical and genetic features of therapy-related myeloid neoplasms after chemotherapy for acute promyelocytic leukemia2010
    • Author(s)
      Imagawa J, Harada Y, Harada H, et al.
    • Journal Title

      Blood

      Volume: 116(26) Pages: 6018-6022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Giant granulocytic sarcoma of the vagina concurrent with acute myeloid leukemia with t(8;21)(q22;q22) translocation2010
    • Author(s)
      Imagawa J, Harada Y, Yoshida T, Sakai A, Sasaki N, Kimura A, Harada H
    • Journal Title

      Int J Hematol

      Volume: 92(3) Pages: 553-555

    • DOI
      10.1007/s12185-010-0676-8
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] [解説]骨髄異形成症候群とレナリドミド―日本における成績.2010
    • Author(s)
      原田浩徳
    • Journal Title

      血液・腫瘍科

      Volume: 60(3) Pages: 348-355

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Giant ganulocytic sarcoma of the vagina concurrent with acute myeloid leukemia with t(8;21)(q22;q22) translocation2010
    • Author(s)
      Imagawa J, Harada Y, Harada H, et al.
    • Journal Title

      International Journal of Hematology

      Volume: 92(3) Pages: 553-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Journal Article] その他の骨髄増殖性疾患と骨髄異形成症候群2009
    • Author(s)
      原田浩徳, 原田結花, 木村昭郎
    • Journal Title

      日本臨牀

      Volume: 67(10) Pages: 1901-1905

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Molecular pathways mediating MDS/ AML with focus on AML1/ RUNX1point mutations2009
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      J Cell Physiol

      Volume: 220 Pages: 16-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Molecular Pathways Mediating MDS/AML with Focus on AML1/RUNX1 Point Mutations2009
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      Journal of Cellular Physiology 220(1)

      Pages: 16-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] その他の骨髄増殖性疾患と骨髄異形成症候群 [特集 骨髄性白血病-病因・治療研究の進歩-] 病因・病態解明発症の分子機序2009
    • Author(s)
      原田浩徳, 原田結花, 木村昭郎
    • Journal Title

      日本臨牀 67(10)

      Pages: 1901-1905

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] 被ばくMDS/AMLの分子発症メカニズム2009
    • Author(s)
      原田結花, 原田浩徳, 川野徳幸, 木村昭郎
    • Journal Title

      放射線生物研究 44(4)

      Pages: 431-446

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Lenalidomide is active in Japanese patients with symptomatic anemia in low-or Intermediate I risk myelodysplastic syndrome (MDS) with a deletion 5q abnormality.2009
    • Author(s)
      原田浩徳, 他13名
    • Journal Title

      International Journal of Hematology 90(3)

      Pages: 353-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] Lenalidomide is active in Japanese patients with symptomatic anemia in low- or intermediate-1 risk myelodysplastic syndromes with a deletion 5q abnormality2009
    • Author(s)
      原田浩徳, et al.
    • Journal Title

      International Journal of Hematology 90(3)

      Pages: 353-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] AML1/ RUNX1 point mutation possibly promotes leukemic transformation in myelodysplastic neoplasms2009
    • Author(s)
      Ding Y, Harada Y, Imagawa J, Kimura A, Harada H
    • Journal Title

      Blood

      Volume: 114(25) Pages: 5201-5205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] 被ばくMDS/ AMLの分子発症メカニズム2009
    • Author(s)
      原田結花, 原田浩徳, 川野徳幸, 木村昭郎
    • Journal Title

      放射線生物研究

      Volume: 44(4) Pages: 431-446

    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Lenalidomide is active in Japanesepatients with symptomatic anemia in low-or Intermediate I risk myelodysplastic syndrome(MDS) with a deletion 5qabnormality2009
    • Author(s)
      Harada H, Watanabe M, Suzuki K, Yamagata S, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Matsuda A, Tohyama K, Taniwaki M, Takeshita K, Takatoku M, Ozawa K
    • Journal Title

      Int J Hematol

      Volume: 90(3) Pages: 353-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Molecular Pathways Mediating MDS/AML with Focus on AML1/RUNX1 Point Mutations2009
    • Author(s)
      Harada Y, Harada H
    • Journal Title

      Journal of Cellular Physiology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] 被ばくMDS/AMLの分子発症メカニズム2009
    • Author(s)
      原田結花
    • Journal Title

      放射線生物研究 44・4

      Pages: 431-446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] AML1/RUNX1 point mutation possibly promotes leukemic transformation in myelodysplastic neoplasms2009
    • Author(s)
      Ding Y, Harada Y, Imagawa J, Kimura A, Harada H
    • Journal Title

      Blood 114(25)

      Pages: 5201-5205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] Possible involvement of RasGRP4 in leukemogenesis2009
    • Author(s)
      Watanabe-Okochi N, Harada Y, Harada H, et al
    • Journal Title

      International Journal of Hematology 89(4)

      Pages: 470-481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] Molecular Pathways Mediating MDS/AML with Focus on AML1/RUNX1 Point Mutations.2009
    • Author(s)
      原田結花, 原田浩徳
    • Journal Title

      Journal of Cellular Physiology 220(1)

      Pages: 16-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] 被ばくMDS/AMLの分子発症メカニズム2009
    • Author(s)
      原田結花、原田浩徳、川野徳幸、木村昭郎
    • Journal Title

      放射線生物研究 44(2)

      Pages: 431-446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] Possible involvement of RasGRP4 in leukemogenesis2009
    • Author(s)
      Watanabe-Okochi N, Oki T, Komeno Y, Kato N, Yuji K, Ono R, Harada Y, Harada H, Hayashi Y, Nakajima H, Nosaka T, KitauraJ, Kitamura T
    • Journal Title

      Int J Hematol

      Volume: 89(4) Pages: 470-481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] 被ばくMDS/AMLの分子発症メカニズム2009
    • Author(s)
      原田結花
    • Journal Title

      放射線生物研究 44(4)

      Pages: 431-446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249041

  • [Journal Article] AML1/RUNX1 point mutation possibly promotes leukemic transformation in myeloproliferative neoplasms2009
    • Author(s)
      Ding Y, Harada Y, Imagawa J, Kimura A, Harada H
    • Journal Title

      Blood 114(25)

      Pages: 5201-5205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Journal Article] セミパラチンスク核実験場近郊住民における骨髄異形成症候群(MDS)の遺伝子学的検討2008
    • Author(s)
      Zharlyganova D, 原田結花、原田浩徳、Chaizhunussova N, Apsalikov K, Zhunussova A, 川野徳幸、木村昭郎、星正治
    • Journal Title

      広島医学 61巻4号

      Pages: 91-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] Health status of radiation exposed residents living near the Semipalatinsk Nuclear Test Site besed on health assessment by interview2008
    • Author(s)
      Hirabayashi K, Kawano N, Ohtaki M, Harada Y, Harada H, Muldagaliyev T, Apsalikov K, Hoshi M
    • Journal Title

      Hiroshima Journal of Medical Science 57(1)

      Pages: 27-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] AML1 mutations induced MDS and MDS/AML in a mouse BMT model2008
    • Author(s)
      Watanabe-Okochi N, Kitaura J, Ono R, Harada H, Harada Y, Komeno Y, Nakajima H, Nosaka T, Inaba T, Kitamura T
    • Journal Title

      Blood 111(8)

      Pages: 4297-4308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] MDSの発症と進展2008
    • Author(s)
      原田浩徳, 他
    • Journal Title

      Biotherapy 22

      Pages: 1-8

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] セミパラチンスク核実験場近郊住民における骨髄異形成症候群(MDS)の遺伝子学的検討2008
    • Author(s)
      Zharlyganova D, 原田結花, 原田浩徳, haizhunussova N, Apsalikov K, Zhunusova A, 川野徳幸, 星正治, 木村昭郎
    • Journal Title

      広島医学 61(4)

      Pages: 91-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] AML1 mutations induced MDS and MDS/AML in a mouse BMT model.2008
    • Author(s)
      Watanabe-Okoch N, Harada H, Harada Y, 他
    • Journal Title

      Blood 111(8)

      Pages: 4297-4308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] Hoshi M : High frequency of AML1/RUNX1 point mutations in radiation-associated myelodysplastic syndrome around Semiparatinsk Nucleaar Test Site2008
    • Author(s)
      Zharlyganova D, Harada H, Harada Y, Shinkarev S, Zhumadilov Z, Zhunusova A, Tchaizhunusova NJ, Apsalikov KN, Kemaikin V, Zhumadilov K, Kawano N, kimura A,
    • Journal Title

      Journal of Radiation Research 49(5)

      Pages: 549-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] Molecular pathogenesis of myelodysplastic syndrome2008
    • Author(s)
      Harada, H., et. al.
    • Journal Title

      Biotherapy 22-1

      Pages: 1-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] High frequency of AML1/RUNX1 point mutations in radiation-associated myelodysplastic syndrome around Semiparatinsk Nucleaar Test Site.2008
    • Author(s)
      Zharlyganova D, Harada H, Harada Y, 他
    • Journal Title

      Journal of Radiation Research 49(5)

      Pages: 549-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510232

  • [Journal Article] MDSの発症と進展2008
    • Author(s)
      原田浩徳, 原田結花
    • Journal Title

      Biotherapy 22(1)

      Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] MDSの発症と進展2008
    • Author(s)
      原田浩徳, 他
    • Journal Title

      Biotherapy 22

      Pages: 1-8

    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] AML1/RUNX1点突然変異を持つMDS/AMLの多段階発症機構. 臨床血液2007
    • Author(s)
      原田浩徳, 原田結花
    • Journal Title

      平成17年度第47回日本臨床血液学会 : MDS特別賞受賞論文 48(7)

      Pages: 541-546

    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] <平成17年度第47回日本臨床血液学会:MDS特別賞受賞論文>AML1/RUNX1点突然変異を持つMDS/AMLの多段階発症機構2007
    • Author(s)
      原田浩徳, 他
    • Journal Title

      臨床血液 48

      Pages: 541-546

    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription2007
    • Author(s)
      Li X-L, Arai Y, Harada H, Shima Y, Yoshida H, Rokudai S, Aikawa Y, Kimura A, Kitabayashi I
    • Journal Title

      Oncogene 26(51)

      Pages: 7231-7239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Journal Article] Hyperactivation of the RAS signaling pathway in myelodysplastic syndromw with AML1/RUNX1 point mutations2007
    • Author(s)
      Harada, H., et. al.
    • Journal Title

      Japanese Journal of Clinical Hematology 48-7

      Pages: 541-546

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] 〈平成17年度第47回日本臨床血液学会:MDS特別賞受賞論文>AML1/RUNX1点突然変異を持つMDS/AMLの多段階発症機構2007
    • Author(s)
      原田浩徳, 他
    • Journal Title

      臨床血液 48

      Pages: 541-546

    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] 〈平成17年度第47回日本臨床血液学会:MDS特別賞受賞論文〉AML1/RUNX1点突然変異を持つMDS/AMLの多段階発症機構2007
    • Author(s)
      原田浩徳, 他
    • Journal Title

      臨床血液 48

      Pages: 541-546

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] Implications of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome (MDS): Future molecular therapeutic directions for MDS.2006
    • Author(s)
      Harada H, et. al.
    • Journal Title

      Current Cancer Drug Targets 6

      Pages: 553-563

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] Implications of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome (MDS) : Future molecular therapeutic directions for MDS2006
    • Author(s)
      Harada, H., et. al.
    • Journal Title

      Current Cancer Drug Targets 6

      Pages: 553-563

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] AML1点変異をもつ骨髄異形成症候群(MDS)の多段階発症機構2006
    • Author(s)
      原田浩徳 他
    • Journal Title

      広島医学 59・4

      Pages: 379-382

    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome (MDS) with AML1 point mutations2006
    • Author(s)
      Harada, H., et. al.
    • Journal Title

      Nagasaki Medical Journal 81

      Pages: 354-357

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] AML1点変異を有する骨髄異形成症候群(MDS)の多段階発症メカニズムの解明2006
    • Author(s)
      原田浩徳 他
    • Journal Title

      長崎医会誌 81・suppl

      Pages: 354-357

    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations2006
    • Author(s)
      Harada, Y., et. al.
    • Journal Title

      Hematology Oncology 53-1

      Pages: 83-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] 特集[骨髄異形成症候群(MDS):病態の解明と最新の治療]MDSの発症と進展の分子機構2006
    • Author(s)
      原田浩徳, 他
    • Journal Title

      血液・腫瘍科 53(2)

      Pages: 136-143

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] Implications of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome(MDS) : Future molecular therapeutic directions for MDS.2006
    • Author(s)
      Harada H, et al.
    • Journal Title

      Current Cancer Drug Targets 6

      Pages: 553-563

    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] 特集[骨髄異形成症候群(MDS) : 病態の解明と最新の治療]MDSの発症と進展の分子構造2006
    • Author(s)
      原田浩徳 他
    • Journal Title

      血液・腫瘍科 53・2

      Pages: 136-143

    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] AML1/RUNX1点変異をもつMDS/AMLの多段階発症機構2006
    • Author(s)
      原田結花, 他
    • Journal Title

      血液・腫瘍科 53(1)

      Pages: 83-90

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] AML1点変異を有する骨髄異形成症候群(MDS)の多段階発症メカニズムの解明2006
    • Author(s)
      原田浩徳, 他
    • Journal Title

      長崎医会誌 81(suppl)

      Pages: 354-357

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] Distinct genetic pathway in molecular pathogenesis of myelodysplastic syndrome (MDS) with AML1 point mutations2006
    • Author(s)
      Harada, H., et. al.
    • Journal Title

      The Journal of the Hiroshima Medical Association 59-4

      Pages: 379-382

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] Molecular pathogenesis of myelodysplastic syndrome2006
    • Author(s)
      Harada, H., et. al.
    • Journal Title

      Hematology Oncology 53-2

      Pages: 136-143

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] AML1点変異をもつ骨髄異形成症候群(MDS)の多段階発症機構2006
    • Author(s)
      原田浩徳, 他
    • Journal Title

      広島医学 59(4)

      Pages: 379-382

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Journal Article] AML1/RUNX1点変異をもとMDS/AMLの多段階発症機構2006
    • Author(s)
      原田結花 他
    • Journal Title

      血液・腫瘍科 53・1

      Pages: 83-90

    • Data Source
      KAKENHI-PROJECT-18591063

  • [Presentation] 家族性MDSにおけるHLTF変異によりPCNAのポリユビキチン化が損なわれDNA損傷が蓄積する2018
    • Author(s)
      高岡賢輔，河津正人，古屋淳史，吉見昭秀，牧宏彰，遠矢嵩，小林隆，南谷泰仁，荒井俊也，上野博則，鈴木憲史，原田浩徳，真部淳，林泰秀，間野博行，黒川峰夫
    • Organizer
      第22回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Dysregulation of histone acetylation by NUP98-HBO1 generates phenotypically and genetically relevant pathogenesis of chronic myelomonocytic leukemia.2018
    • Author(s)
      林嘉宏，原田結花，丁曄，松井啓隆，鍵山侑希，加藤菜穂子，北林一生，岩間厚志，北村俊雄，原田浩徳．
    • Organizer
      第22回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] HLTF mutation in familial MDS accumulates DNA damage through impaired PCNA polyubiquitination.2018
    • Author(s)
      高岡賢輔，河津正人，古屋淳史，吉見昭秀，牧宏彰，遠矢嵩，小林隆，南谷泰仁，荒井俊也，上野博則，鈴木憲史，原田浩徳，真部淳，林泰秀，間野博行，黒川峰夫．
    • Organizer
      第22回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] ヒストンアセチル化制御破綻による慢性骨髄単球性白血病の新規発症機序の解明2018
    • Author(s)
      林嘉宏，原田結花，丁曄，松井啓隆，鍵山侑希，加藤菜穂子，北林一生，岩間厚志，北村俊雄，原田浩徳
    • Organizer
      第22回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] RUNX3スーパーエンハンサーによる白血病幹細胞の病態基盤解明2017
    • Author(s)
      横溝貴子，田中大樹，原田結花，大島基彦，金井昭教，岩間厚志，大里元美，原田浩徳，指田吾郎
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 家族性骨髄異形成症候群の全国調査2017
    • Author(s)
      黒川峰夫，古屋淳史，高岡賢輔，遠矢　嵩，小林　隆，原田浩徳，真部　淳，林　泰秀
    • Organizer
      平成28年度厚生労働科学研究費補助金　難治性疾患等政策研究事業　特発性造血器障害に関する調査研究班会議
    • Place of Presentation
      東京大学（東京都文京区）
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Identification of critical mediator for bone marrow fibrosis in MDS using novel RUNX1-mutatant/HMGA2-overexpression mouse model2017
    • Author(s)
      Harada H, Hayashi Y, Shingai N, Kagiyama Y, Harada Y
    • Organizer
      The 21st International RUNX Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Human Germline HLTF E259K Mutation Identified in Familial MDS Patients Accumulates DNA Damage through Impaired PCNA Polyubiquitination2017
    • Author(s)
      Takaoka K, Kawazu M, Koya J, Yoshimi A, Masamoto Y, Maki H, Toya T, Kobayashi T, Nannya Y, Arai S, Ueno H, Suzuki K, Harada H, Manabe A, Hayashi Y, Mano H, Kurokawa M
    • Organizer
      59th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 家族性骨髄異形成症候群から得られたHLTF変異によりPCNAのポリユビキチン化が損なわれDNA損傷が蓄積する2017
    • Author(s)
      高岡賢輔，河津正人，古屋淳史，吉見昭秀，牧宏彰，遠矢嵩，南谷泰仁，荒井俊也，上野博則，原田浩徳，林泰秀，間野博行，黒川峰夫．
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 遺伝子異常による骨髄系造血器腫瘍の発症機序解明2017
    • Author(s)
      原田浩徳
    • Organizer
      東京大学医科学研究所共同研究拠点事業　平成28年度成果報告会
    • Place of Presentation
      東京大学医科学研究所（東京都港区）
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] MDS分子病態研究の進歩2017
    • Author(s)
      原田浩徳
    • Organizer
      第79回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 骨髄異形成症候群およびその類縁疾患における骨髄線維化機序の解明．2017
    • Author(s)
      新谷直樹，原田浩徳，原田結花，荒木真理人，小松則夫．
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 遺伝子異常による骨髄系造血器腫瘍の発症機序解明2017
    • Author(s)
      原田浩徳
    • Organizer
      東京大学医科学研究所共同研究拠点事業　平成28年度成果報告会
    • Place of Presentation
      東京大学医科学研究所（東京都港区）
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] ポリコーム遺伝子Pcgf1の欠損は、JAK2V617Fによる骨髄線維症の発症を著明に促進する2017
    • Author(s)
      篠田大輔，中島やえ子，大島基彦，更屋敦則，指田吾郎，原田浩徳，下田和哉，古関明彦，岩間厚志
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] ポリコーム遺伝子Pcgf1の欠損は、JAK2V617Fによる骨髄線維症の発症を著明に促進する．2017
    • Author(s)
      篠田大輔，中島やえ子，大島基彦，更屋敦則，指田吾郎，原田浩徳，下田和哉，古関明彦，岩間厚司．
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Molecular mechanisms to development myeloid neoplasms by RUNx1 or MLL chimeras in human CD34+ cells.2017
    • Author(s)
      Harada H, Shingai N, Nshio M, Komatsu N, Harada Y.
    • Organizer
      ISEH 46th Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 造血器腫瘍における抗がん剤、G-CSF製剤が与える影響の解明2017
    • Author(s)
      新谷直樹，西尾美和子，原田結花，原田浩徳．
    • Organizer
      第21回造血器腫瘍研究会
    • Place of Presentation
      熊本大学（熊本県熊本市）
    • Year and Date
      2017-02-17
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 造血器腫瘍における抗がん剤、G-CSF製剤が与える影響の解明2017
    • Author(s)
      新谷直樹，西尾美和子，原田結花，原田浩徳
    • Organizer
      第21回造血器腫瘍研究会
    • Place of Presentation
      熊本大学（熊本県熊本市）
    • Year and Date
      2017-02-17
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 家族性骨髄異形成症候群の全国調査2017
    • Author(s)
      黒川峰夫，古屋淳史，高岡賢輔，遠矢　嵩，小林　隆，原田浩徳，真部　淳，林　泰秀．
    • Organizer
      平成28年度厚生労働科学研究費補助金　難治性疾患等政策研究事業　特発性造血器障害に関する調査研究班会議
    • Place of Presentation
      東京大学（東京都文京区）
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] HIF1Aシグナルの亢進は骨髄異形成症候群の病態形成において中心的な役割を果たす2017
    • Author(s)
      林嘉宏, Zhang Y, Yan Z, 指田吾郎, Chetai K, Olsson A, 原田浩徳, 他
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 家族性MDSにおけるHLTF変異によりPCNAのポリユビキチン化が損なわれDNA損傷が蓄積する2017
    • Author(s)
      高岡賢輔，河津正人，古屋淳史，吉見昭秀，牧宏彰，遠矢嵩，小林隆，南谷泰仁，荒井俊也，上野博則，鈴木憲史，原田浩徳，真部淳，林泰秀，間野博行，黒川峰夫
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] スプライシング関連遺伝子異常が運命づけるMDS表現型の解析2017
    • Author(s)
      新谷直樹，原田結花，櫻井弘子，尾形洋輔，赤羽浩太，西尾美和子，土岐典子，大橋一輝，萩原政夫，小松則夫，原田浩徳
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 骨髄異形成症候群およびその類縁疾患における骨髄線維化機序の解明2017
    • Author(s)
      新谷直樹，原田浩徳，原田結花，荒木真理人，小松則夫
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] RUNX3 promotes the development of MDS/MPN Overlap Syndrome via enhancing expression of Myc in the absence of Tet22017
    • Author(s)
      Yokomizo T, Tanaka D, Kubota S, Oshima M, Harada Y, Kanai A, Iwama A, Harada H, Osato M, Sashida G
    • Organizer
      59th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Molecular mechanisms to development myeloid neoplasms by RUNX1 or MLL chimeras in human CD34+ cells2017
    • Author(s)
      Harada H, Shingai N, Nishio M, Komatsu N, Harada Y
    • Organizer
      ISEH 46th Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Human Germline HLTF E259K Mutation Identified in Familial MDS Patients Accumulates DNA Damage through Impaired PCNA Polyubiquitination.2017
    • Author(s)
      Takaoka K, Kawazu M, Koya J, Yoshimi A, Masamoto Y, Maki H, Toya T, Kobayashi T, Nannya Y, Arai S, Ueno H, Suzuki K, Harada H, Manabe A, Hayashi Y, Mano H, Kurokawa M.
    • Organizer
      59th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] スプライシング関連遺伝子異常が運命づけるMDS表現型の解析2017
    • Author(s)
      新谷直樹，原田結花，櫻井弘子，尾形洋輔，赤羽浩太，西尾美和子，土岐典子，大橋一輝，萩原政夫，小松則夫，原田浩徳．
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] RUNX3スーパーエンハンサーによる白血病幹細胞の病態基盤解明2017
    • Author(s)
      横溝貴子，大島基彦，原田浩徳，岩間厚志，大里元美，指田吾郎．
    • Organizer
      第21回造血器腫瘍研究会
    • Place of Presentation
      熊本大学（熊本県熊本市）
    • Year and Date
      2017-02-17
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] RUNX3スーパーエンハンサーによる白血病幹細胞の病態基盤解明2017
    • Author(s)
      横溝貴子，大島基彦，原田浩徳，岩間厚志，大里元美，指田吾郎
    • Organizer
      第21回造血器腫瘍研究会
    • Place of Presentation
      熊本大学（熊本県熊本市）
    • Year and Date
      2017-02-17
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 家族性骨髄異形成症候群から得られたHLTF変異によりPCNAのポリユビキチン化が損なわれDNA損傷が蓄積する2017
    • Author(s)
      高岡賢輔，河津正人，古屋淳史，吉見昭秀，牧宏彰，遠矢嵩，南谷泰仁，荒井俊也，上野博則，原田浩徳，林泰秀，間野博行，黒川峰夫
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] RUNX3スーパーエンハンサーによる白血病幹細胞の病態基盤解明2017
    • Author(s)
      横溝貴子，田中大樹，原田結花，大島基彦，金井昭教，岩間厚志，大里元美，原田浩徳，指田吾郎．
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] XPO1 inhibition targets transcriptional vulnerability of FLT3-ITD+D835 double mutant AML through p53 accumulation and inhibition of oncogenic transcription factors: Lesson learned from CAGE sequencing of primary AML cells.2017
    • Author(s)
      Yamatani K, Tabe Y, Sekihara K, Yang H, Saitoh K, Zhang W, Ikeo K, Kinjo S, Mogushi K, Hosoya M, Hayashizaki Y, Yamanaka Y, Harada H, Miida T, Konopleva M, Andreeff M.
    • Organizer
      59th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Identification of critical mediator for bone marrow fibrosis in MDS using novel RUNX1-mutatant/HMGA2-overexpression mouse model.2017
    • Author(s)
      Harada H, Hayashi Y, Shingai N, Kagiyama Y, Harada Y.
    • Organizer
      The21st International RUNX Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 環状鉄芽球を伴う骨髄異形成症候群におけるスプライシング関連遺伝子異常2017
    • Author(s)
      尾形洋輔，新谷直樹，赤羽浩太，西尾美和子，土岐典子，香西康司，萩原政夫，大橋一輝，小松則夫，原田結花，原田浩徳
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 家族性MDSにおけるHLTF変異によりPCNAのポリユビキチン化が損なわれDNA損傷が蓄積する．2017
    • Author(s)
      高岡賢輔，河津正人，古屋淳史，吉見昭秀，牧宏彰，遠矢嵩，小林隆，南谷泰仁，荒井俊也，上野博則，鈴木憲史，原田浩徳，真部淳，林泰秀，間野博行，黒川峰夫．
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 急性骨髄性白血病に対するターゲットシーケンスパネル2017
    • Author(s)
      松下弘道，川井英嗣，田中政之，原田浩徳，原田結花，天木惇，盛音，椎名隆，鬼塚真仁，安藤潔．
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] HIF1Aシグナルの亢進は骨髄異形成症候群の病態形成において中心的な役割を果たす2017
    • Author(s)
      林嘉宏, Zhang Y, Yan Z, 指田吾郎, Chetai K, Olsson A, 原田浩徳, Shih L-Y, Tse W, Bridges J, Zheng Y, Witte D, Caligiuri M, Qu C-K, Whang Q-F, Salomonis N, Grimes HL, Nimer S, Xiao Z, Huang G
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] XPO1 inhibition targets transcriptional vulnerability of FLT3-ITD+D835 double mutant AML through p53 accumulation and inhibition of oncogenic transcription factors: Lesson learned from CAGE sequencing of primary AML cells2017
    • Author(s)
      Yamatani K, Tabe Y, Sekihara K, Yang H, Saitoh K, Zhang W, Ikeo K, Kinjo S, Mogushi K, Hosoya M, Hayashizaki Y, Yamanaka Y, Harada H, Miida T, Konopleva M, Andreeff M
    • Organizer
      59th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 環状鉄芽球を伴う骨髄異形成症候群におけるスプライシング関連遺伝子異常2017
    • Author(s)
      尾形洋輔，新谷直樹，赤羽浩太，西尾美和子，土岐典子，香西康司，萩原政夫，大橋一輝，小松則夫，原田結花，原田浩徳．
    • Organizer
      79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] MDS分子病態研究の進歩2017
    • Author(s)
      原田浩徳
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 急性骨髄性白血病に対するターゲットシーケンスパネル2017
    • Author(s)
      松下弘道，川井英嗣，田中政之，原田浩徳，原田結花，天木惇，盛音，椎名隆，鬼塚真仁，安藤潔
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] RUNX3 promotes the development of MDS/MPN Overlap Syndrome via enhancing expression of Myc in the absence of Tet2.2017
    • Author(s)
      Yokomizo T, Tanaka D, Kubota S, Oshima M, Harada Y, Kanai A, Iwama A, Harada H, Osato M, Sashida G.
    • Organizer
      59th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] ABCG2 High Expression Is Specific to Advanced MDS and Promotes Cytopenia in Mouse BMT Model.2016
    • Author(s)
      Kawabata K, Hayashi Y, Inoue D, Kitaura J, Goyama S, Harada Y, Harada H, Aburatani H, Kitamura T.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Nationwide epidemiological surver of familial myelodysplastic syndromes/acute myeloid leukemia in Japan.2016
    • Author(s)
      Takaoka K, Yoshimi A, Koya J, Toya T, Kobayashi T, Nannya Y, Ueno H, Suzuki K, Harada H, Manabe A, Hayashi Y, Kurokawa M.
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Analysis of Asxl1-MT conditional knock-in mice2016
    • Author(s)
      Nagase R, Inoue D, Kanai A, Saika M, Fujino T, Kawabata K, Tanaka Y, Fukuyama T, Harada H, Goyama S, Honda H, Kitamura T
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 骨髄異形成症候群の基礎知識2016
    • Author(s)
      原田浩徳
    • Organizer
      第64回日本輸血・細胞治療学会総会
    • Place of Presentation
      国立京都国際会館（京都府京都市）
    • Year and Date
      2016-04-28
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Expansion of ABCG2 is regulated in EZH2-related MDS and associated with its pathogenesis.2016
    • Author(s)
      Kawabata K, Hayashi Y, Inoue D, Sakurai H, Mizuno H, Kitaura J, Harada Y, Harada H, Goyama S, Aburatani H, Ishii M, Kitamura T.
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Analysis of Asxl1-MT conditional knock-in mice.2016
    • Author(s)
      Nagase R, Inoue D, Kanai A, Saika M, Fujino T, Kawabata K, Tanaka Y, Fukuyama T, Harada H, Goyama S, Honda H, Kitamura T.
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Novel fatty acid oxidation inhibitor Avocatinb induces AMPK-dependent apoptosis of AML cells co-cultured with BM-adipocytes.2016
    • Author(s)
      Tabe Y, Sekihara K, Saitoh K, Monma N, Ikeo K, Kaczkowski B, Zhang W, Yamanaka Y, Miida T, Shah N, Harada H, Hayashizaki Y, Konopleva M, Andreeff M.
    • Organizer
      58th ASH Annual Meeting and Exposition
    • Place of Presentation
      SanDiego, CA (USA)
    • Year and Date
      2016-12-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Dysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes2016
    • Author(s)
      原田浩徳
    • Organizer
      第20回造血器腫瘍研究会
    • Place of Presentation
      かずさアーク（千葉県木更津市）
    • Year and Date
      2016-02-12
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] ABCG2 High Expression Is Specific to Advanced MDS and Promotes Cytopenia in Mouse BMT Model2016
    • Author(s)
      Kawabata K, Hayashi Y, Inoue D, Kitaura J, Goyama S, Harada Y, Harada H, Aburatani H, Kitamura T
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 骨髄異形成症候群の基礎知識2016
    • Author(s)
      原田浩徳
    • Organizer
      第64回日本輸血・細胞治療学会総会
    • Place of Presentation
      国立京都国際会館（京都府京都市）
    • Year and Date
      2016-04-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Nationwide epidemiological surver of familial myelodysplastic syndromes/acute myeloid leukemia2016
    • Author(s)
      Takaoka K, Yoshimi A, Koya J, Toya T, Kobayashi T, Nannya Y, Ueno H, Harada H, Hayashi Y, Kurokawa M
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Nationwide epidemiological surver of familial myelodysplastic syndromes/acute myeloid leukemia in Japan2016
    • Author(s)
      Takaoka K, Yoshimi A, Koya J, Toya T, Kobayashi T, Nannya Y, Ueno H, Suzuki K, Harada H, Manabe A, Hayashi Y, Kurokawa M
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Expansion of ABCG2 is regulated in EZH2-related MDS and associated with its pathogenesis2016
    • Author(s)
      Kawabata K, Hayashi Y, Inoue D, Sakurai H, Mizuno H, Kitaura J, Harada Y, Harada H, Goyama S, Aburatani H, Ishii M, Kitamura T
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] ysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes2016
    • Author(s)
      Harada H, Harada Y, Sakurai H, Kitamura T, Komatsu N
    • Organizer
      The eleventh international workshop on molecular aspects of myeloid stem cell development and leukemia
    • Place of Presentation
      Cincinnati Children's Hospital Medical Center, Cincinnati (Ohio, USA)
    • Year and Date
      2016-05-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 骨髄異形成症候群の分子病態と治療2016
    • Author(s)
      原田浩徳
    • Organizer
      第34回日本血液学会北陸地方会
    • Place of Presentation
      石川県立中央病院（石川県金沢市）
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Dysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes2016
    • Author(s)
      原田浩徳
    • Organizer
      第20回造血器腫瘍研究会
    • Place of Presentation
      木更津
    • Year and Date
      2016-02-12
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 家族性骨髄異形成症候群/急性骨髄性白血病の本邦における疫学2016
    • Author(s)
      Takaoka K, Yoshimi A, Koya J, Kobayashi T, Ueno H, Suzuki K, Harada H, Manabe A, Hayashi Y, Kurokawa M
    • Organizer
      第14回日本臨床腫瘍学会学術集会
    • Place of Presentation
      神戸国際会議場（兵庫県神戸市）
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Dysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes.2016
    • Author(s)
      Harada H, Harada Y, Sakurai H, Kitamura T, Komatsu N.
    • Organizer
      The eleventh international workshop on molecular aspects of myeloid stem cell development and leukemia
    • Place of Presentation
      Cincinnati Children's Hospital Medical Center, Cincinnati (Ohio, USA)
    • Year and Date
      2016-05-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] 家族性骨髄異形成症候群/急性骨髄性白血病の本邦における疫学2016
    • Author(s)
      Takaoka K, Yoshimi A, Koya J, Kobayashi T, Ueno H, Suzuki K, Harada H, Manabe A, Hayashi Y, Kurokawa M.
    • Organizer
      第14回日本臨床腫瘍学会学術集会
    • Place of Presentation
      神戸国際会議場（兵庫県神戸市）
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Molecular mechanisms to develop myeloid neoplasms by RUNX1 or MLL chimeras in human CD34 cells2016
    • Author(s)
      Shingai N, Harada Y, Nishio M, Harada H
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] 骨髄異形成症候群の分子病態と治療2016
    • Author(s)
      原田浩徳
    • Organizer
      第34回日本血液学会北陸地方会
    • Place of Presentation
      石川県立中央病院（石川県金沢市）
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Nationwide epidemiological surver of familial myelodysplastic syndromes/acute myeloid leukemia.2016
    • Author(s)
      Takaoka K, Yoshimi A, Koya J, Toya T, Kobayashi T, Nannya Y, Ueno H, Harada H, Hayashi Y, Kurokawa M.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Disordered Gene Expression in Hematologic Malignancy,including Disordered Epigenetic Regulation2016
    • Author(s)
      Tabe Y, Sekihara K, Saitoh K, Monma N, Ikeo K, Kaczkowski B, Zhang W, Yamanaka Y, Miida T, Shah N, Harada H, Hayashizaki Y, Konopleva M, Andreeff M
    • Organizer
      58th ASH Annual Meeting and Exposition
    • Place of Presentation
      SanDiego, CA (USA)
    • Year and Date
      2016-12-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09831

  • [Presentation] Molecular mechanisms to develop myeloid neoplasms by RUNX1 or MLL chimeras in human CD34 cells.2016
    • Author(s)
      Shingai N, Harada Y, Nishio M, Harada H.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Analysis of MDS mice model induced by ASXL1 and RUNX1 mutations.2015
    • Author(s)
      Nagase R, Inoue D, Saika M, Hou H-A, Chou W-C, Kawabata KC, Harada H, Goyama S, Hwai-Fang T, Kitamura T
    • Organizer
      The 77th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      ホテル日航金沢　他（石川県金沢市）
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Investigation of a causal gene of familial myelodysplastic syndromes2015
    • Author(s)
      Takaoka K, Kawazu M, Yoshimi A, Toya T, Kobayashi T, Nannya Y, Ueno H, Suzuk K, Harada H, Manabe A, Hayashi Y, Mano H, Kurokawa M
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development2015
    • Author(s)
      Hayashi Y, Zhang Y, Yan X, Choi K, Sashida G, Dong Y , Xu Z, Wu L, Chen A, Sun X, Olsson A, Harada H, Shih L-Y, Tse W, Bridges J, Witte DP, Wang Q , Caligiuri MA, Grimes HL, Nimer SD, Xiao Z, Huang G
    • Organizer
      57th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco, CA
    • Year and Date
      2015-12-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Dysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Kitamura T, Komatsu N, Harada H
    • Organizer
      57th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco, CA
    • Year and Date
      2015-12-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of myelodysplastic syndromes/ myeloproliferative neoplasms2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Kitamura T, Komatsu N, Harada H
    • Organizer
      ISEH 44th Annual Scientific Meeting
    • Place of Presentation
      Kyoto International Conference Center (Kyoto, Japan)
    • Year and Date
      2015-09-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Truncated form EZH2 promotes stemness of MDS via derepression of stemness related genes2015
    • Author(s)
      Kawabata KC, Inoue D, Hayashi Y, Harada H, Goyama S, Kitaura J, Kitamura T
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] A candidate causal gene of familial myelodysplastic syndromes2015
    • Author(s)
      Takaoka K, Kawazu M, Yoshimi A, Toya T, Kobayashi T, Nannya Y, Ueno H, Harada H, Hayashi Y, Mano H, Kurokawa M
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of myelodysplastic syndromes/ myeloproliferative neoplasms2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Kitamura T, Komatsu N, Harada H
    • Organizer
      ISEH 44th Annual Scientific Meeting
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2015-09-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development2015
    • Author(s)
      Hayashi Y, Zhang Y, Yan X, Choi K, Sashida G, Dong Y , Xu Z, Wu L, Chen A, Sun X, Olsson A, Harada H, Shih L-Y, Tse W, Bridges J, Witte DP, Wang Q , Caligiuri MA, Grimes HL, Nimer SD, Xiao Z, Huang G
    • Organizer
      57th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco, CA (USA)
    • Year and Date
      2015-12-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of MDS/MPN2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Doki N, Kakihana K, Ohashi K, Kitamura T, Komatsu N, Harada H
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of MDS/MPN2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Doki N, Kakihana K, Ohashi K, Kitamura T, Komatsu N, Harada H
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      （愛知県名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] A Patient-Derived EZH2 Mutant Induces MDS-like Diseases with Derepressed ABCG2 Expression in Mice2015
    • Author(s)
      Kawabata KC, Inoue D, Kitaura J, Harada Y, Goyama S, Harada H, Aburatani H, Kitamura T
    • Organizer
      57th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco, CA (USA)
    • Year and Date
      2015-12-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] A Patient-Derived EZH2 Mutant Induces MDS-like Diseases with Derepressed ABCG2 Expression in Mice2015
    • Author(s)
      Kawabata KC, Inoue D, Kitaura J, Harada Y, Goyama S, Harada H, Aburatani H, Kitamura T
    • Organizer
      57th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco, CA
    • Year and Date
      2015-12-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Analysis of MDS mice model induced by ASXL1 and RUNX1 mutations2015
    • Author(s)
      Nagase R, Inoue D, Saika M, Hou H-A, Chou W-C, Kawabata KC, Harada H, Goyama S, Hwai-Fang T, Kitamura T
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Dysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Kitamura T, Komatsu N, Harada H
    • Organizer
      57th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco, CA (USA)
    • Year and Date
      2015-12-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of myelodysplastic syndromes2015
    • Author(s)
      Harada H, Sakurai H, Harada Y, Kitamura T, Komatsu N
    • Organizer
      The RUNX Transcription Factors in Development and Disease
    • Place of Presentation
      Rehovot, Israel
    • Year and Date
      2015-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Truncated form EZH2 promotes stemness of MDS via derepression of stemness related genes2015
    • Author(s)
      Kawabata KC, Inoue D, Hayashi Y, Harada H, Goyama S, Kitaura J, Kitamura T
    • Organizer
      The 77th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      ホテル日航金沢　他（石川県金沢市）
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of MDS/MPN2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Doki N, Kakihana K, Ohashi K, Kitamura T, Komatsu N, Harada H
    • Organizer
      The 77th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      ホテル日航金沢　他（石川県金沢市）
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Nationwide epidemiological survey of familial platelet disorder in Japan2015
    • Author(s)
      Toya T, Yoshimi A, Nannya Y, Takaoka K, Kirito K, Nakajima H, Hayashi Y, Takahashi T, Harada H, Komatsu N, Ichikawa M, Kurokawa M
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Nationwide epidemiological survey of familial platelet disorder in Japan2015
    • Author(s)
      Toya T, Yoshimi A, Takaoka K, Nannya Y, Kirito K, Ito E, Nakajima H, Hayashi Y, Takahashi T, Moriya-Saito A, SuzukiK, Harada H, Komatsu N, Usuki K, Ichikawa M, Kurokawa M
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Investigation of a causal gene of familial myelodysplastic syndromes2015
    • Author(s)
      Takaoka K, Kawazu M, Yoshimi A, Toya T, Kobayashi T, Nannya Y, Ueno H, Suzuk K, Harada H, Manabe A, Hayashi Y, Mano H, Kurokawa M
    • Organizer
      The 77th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      ホテル日航金沢　他（石川県金沢市）
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Nationwide epidemiological survey of familial platelet disorder in Japan2015
    • Author(s)
      Toya T, Yoshimi A, Takaoka K, Nannya Y, Kirito K, Ito E, Nakajima H, Hayashi Y, Takahashi T, Moriya-Saito A, SuzukiK, Harada H, Komatsu N, Usuki K, Ichikawa M, Kurokawa M
    • Organizer
      The 77th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      ホテル日航金沢　他（石川県金沢市）
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Inactivation of EZH2 by truncated form mutation depresses stemness-related genes and promote myelodysplastic syndrome2015
    • Author(s)
      Kawabata KC, Inoue D, Hayashi Y, Harada H, Goyama S, Kitaura J, Kitamura T
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of MDS/MPN2015
    • Author(s)
      Sakurai H, Harada Y, Matsui H, Nakajima H, Doki N, Kakihana K, Ohashi K, Kitamura T, Komatsu N, Harada H
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K09460

  • [Presentation] Overexpression of RUNX1 short isoform plays a pivotal role in the development of myelodysplastic syndromes2015
    • Author(s)
      Harada H, Sakurai H, Harada Y, Kitamura T, Komatsu N
    • Organizer
      The RUNX Transcription Factors in Development and Disease
    • Place of Presentation
      Rehovot (Israel)
    • Year and Date
      2015-10-18
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] 地理情報システムを用いた広島原爆入市被爆者の移動経路の解析2014
    • Author(s)
      佐藤裕哉, 佐藤健一, 原 憲行, 布施博之, 冨田哲治, 原田結花, 大瀧 慈
    • Organizer
      2014年人文地理学会大会
    • Place of Presentation
      広島大学（東広島）
    • Year and Date
      2014-11-09
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] 急性骨髄性白血病に関係するCCDC26のマウスホモログ同定と発現解析2014
    • Author(s)
      吉川量子、原田浩徳、原田結花、石田敦彦、山崎岳、平野哲男
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-24510277

  • [Presentation] 広島原爆入市被曝者の移動経路の分析2014
    • Author(s)
      佐藤裕哉, 佐藤健一, 原 憲行, 布施博之, 原田結花
    • Organizer
      第55回原子爆弾後障害研究会
    • Place of Presentation
      長崎
    • Year and Date
      2014-06-01
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] 非コードRNA CCDC26がc-Kitの転写調節を介して骨髄性白血病細胞の増殖を制御している2014
    • Author(s)
      平野哲男、吉川量子、原田浩徳、原田結花、石田敦彦、山崎岳
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-24510277

  • [Presentation] 広島原爆入市被爆者の移動経路の把握による健康影響評価の試み2014
    • Author(s)
      佐藤裕哉,佐藤健一,原　憲行,原田結花
    • Organizer
      2014年日本地理学会春季学術大会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      EMBO Workshop RUNX transcription factors in development & disease (19th International RUNX Workshop)
    • Place of Presentation
      Wilsede (Germany)
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      EMBO Workshop RUNX transcription factors in development & disease (19th International RUNX Workshop)
    • Place of Presentation
      Wilsede, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] RUNX1 mutant collaborates with BMI1 overexpression in the development of human and murine MDS/AML2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Ding Y, Matsui H, Sashida G, Iwama A, Kitamura T
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] C-terminal-truncating ASXL1 mutations induce MDS via inhibition of PRC22013
    • Author(s)
      Inoue D, Kitaura J, Togami K, Nishimura K, Enomoto Y, Uchida T, Kagiyama Y, Kawabata KC, Nakahara F, Oki T, Harada H, Ochiya T, Aburatani H, Kimura H, Thol F, Heuser M, Levine RL, Abdel-Wahab O, Kitamura T
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] Preliminary results of a randamized dose-finding study of darbepoetin alfa in MDS in Japan and Korea2013
    • Author(s)
      Harada H, Jun Ho Jang, Suzuki K, Tsudo M, Ishikawa T, Uike N, Hidaka M, Usuki K, Shimizu S, Kim Y-J, Kim H, Kizaki M, Chiba S, Nannya Y, Yonemura Y, Sawa M, Ogura H, Nakazato T, Kumagai T, Kiguchi T, Takahashi T, Irie S, Yoon S-S, Shin J-J, Young Don Joo, Yoo Hong Min, Sohn S-K, Mitani K, Sawada K, Lee J-H, Kim H-J
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] The genetic landscape of FPD/AML revealed CDC25C mutation as a driver that promotes malignant transformation2013
    • Author(s)
      Yoshimi A, Toya T, Nakagawa M, Kawazu M, Nannya Y, Ichikawa M, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Mano H, Kurokawa M
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] C-terminal-truncating ASXL1 mutations induce MDS via inhibition of PRC22013
    • Author(s)
      Inoue D, Kitaura J, Togami K, Nishimura K, Enomoto Y, Uchida T, Kagiyama Y, Kawabata KC, Nakahara F, Oki T, Harada H, Ochiya T, Aburatani H, Kimura H, Thol F, Heuser M, Levine RL, Abdel-Wahab O, Kitamura T
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] アザシチジンによるMDS治療．［ランチョンセミナー：骨髄異形成症候群（MDS）の分子病態、診断と治療］2013
    • Author(s)
      原田浩徳
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] RUNX1 mutant collaborates with BMI1 overexpression in the development of human and murine MDS/AML2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Ding Y, Matsui H, Sashida G, Iwama A, Kitamura T
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] Preliminary results of a randamized dose-finding study of darbepoetin alfa in MDS in Japan and Korea2013
    • Author(s)
      Shibayama H, Harada H, Jun Ho Jang, Suzuki K, Tsudo M, Ishikawa T, Uike N, Hidaka M, Usuki K, Shimizu S, Kim Y-J, Kim H, Kizaki M, Chiba S, Nannya Y, Yonemura Y, Sawa M, Ogura H, Nakazato T, Kumagai T, Kiguchi T, Takahashi T, Irie S, Mitani K, Sawada K, et al.
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] 原爆・被ばく関連資料データベース（新聞記事）のテキスト解析の試み2013
    • Author(s)
      佐藤裕哉,佐藤健一,原田結花,嶋本浩子,原　憲行,原田浩徳,大瀧　慈,田代　聡
    • Organizer
      54回原子爆弾後障害研究会
    • Place of Presentation
      広島市
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX3 overexpression may participaten in the development of MDS/AML2013
    • Author(s)
      Miyama T, Harada Y, Ichinose T, Harada H
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] The genetic landscape of FPD/AML revealed CDC25C mutation as a driver that promotes malignant transformation2013
    • Author(s)
      Yoshimi A, Toya T, Nakagawa M, Kawazu M, Nannya Y, Ichikawa M, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Mano H, Kurokawa M
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] 新聞記事データベース応用の試み―見出しから社会の関心の変化は読み取れるか？－2013
    • Author(s)
      佐藤裕哉,佐藤健一,原田結花,嶋本浩子,原憲行,原田浩徳,大瀧慈,田代聡
    • Organizer
      原子爆弾後障害研究会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] アザシチジンによるMDS治療．［ランチョンセミナー：骨髄異形成症候群（MDS）の分子病態、診断と治療］2013
    • Author(s)
      原田浩徳
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] The genetic landscape of FPD/AML revealed CDC25C mutation as a driver that promotes malignant transformation2013
    • Author(s)
      Yoshimi A, Toya T, Nakagawa M, Kawazu M, Nannya Y, Ichikawa M, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Mano H, Kurokawa M
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX1 mutant collaborates with BMI1 overexpression in the development of human and murine MDS/AML2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Ding Y, Matsui H, Sashida G, Iwama A, Kitamura T
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)2013
    • Author(s)
      Kobayashi T, Nannya Y, Ichikawa M, Kohara T, Kobune M, Harada H, Yonemura Y, Matsuda A, Kawabata H, Tohyama K, Miyazaki Y, Kurokawa M
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      EMBO Workshop RUNX transcription factors in development & disease (19th International RUNX Workshop)
    • Place of Presentation
      Wilsede, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] RUNX3 overexpression may participaten in the development of MDS/AML2013
    • Author(s)
      Miyama T, Harada Y, Ichinose T, Harada H
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] RUNX1 mutant collaborates with BMI1 overexpression in the development of human and murine MDS/AML2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Ding Y, Matsui H, Sashida G, Iwama A, Kitamura T
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] Preliminary results of a randamized dose-finding study of darbepoetin alfa in MDS in Japan and Korea2013
    • Author(s)
      Shibayama H, Harada H, Suzuki K, Tsudo M, Ishikawa T, Uike N, Hidaka M, Usuki K, Shimizu S, Kizaki M, Chiba S, Nannya Y, Yonemura Y, Sawa M, Ogura H, Nakazato T, Kumagai T, Kiguchi T, Takahashi T, Irie S, Mitani K, Sawada K
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2013
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      19th International RUNX Workshop
    • Place of Presentation
      Wilsede, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] アザシチジンによるMDS治療[ランチョンセミナー : 骨髄異形成症候群(MDS)の分子病態,診断と治療]2013
    • Author(s)
      原田浩徳
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] C-Terminal-truncating ASXL1 mutations induce MDS via inhibition of PRC22013
    • Author(s)
      Inoue D, Kitaura J, Togami K, Nishimura K, Enomoto Y, Uchida T, Kagiyama Y, Kawabata KC, Nakahara F, Oki T, Harada H, Ochiya T, Aburatani H, Kimura H, Thol F, Heuser M, Levine RL, Abdel-Wahab O, Kitamura T
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)2013
    • Author(s)
      Kobayashi T, Nannya Y, Ichikawa M, Kohara T, Kobune M, Harada H, Yonemura Y, Matsuda A, Kawabata H, Tohyama K, Miyazaki Y, Kurokawa M
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)2013
    • Author(s)
      Kobayashi T, Nannya Y, Ichikawa M, Kohara T, Kobune M, Harada H, Yonemura Y, Matsuda A, Kawabata H, Tohyama K, Miyazaki Y, Kurokawa M
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)2013
    • Author(s)
      Kobayashi T, Nannya Y, Ichikawa M, Kohara T, Kobune M, Harada H, Yonemura Y, Matsuda A, Kawabata H, Tohyama K, Miyazaki Y, Kurokawa M
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] C-terminal-truncating ASXL1 mutations induce MDS via inhibition of PRC22013
    • Author(s)
      Inoue D, Kitaura J, Togami K, Nishimura K, Enomoto Y, Uchida T, Kagiyama Y, Kawabata KC, Nakahara F, Oki T, Harada H, Ochiya T, Aburatani H, Kimura H, Thol F, Heuser M, Levine RL, Abdel-Wahab O, Kitamura T
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] RUNX3 overexpression may participaten in the development of MDS/AML2013
    • Author(s)
      Miyama T, Harada Y, Ichinose T, Harada H
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX3 overexpression may participaten in the development of MDS/AML2013
    • Author(s)
      Miyama T, Harada Y, Ichinose T, Harada H
    • Organizer
      The 75th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] The genetic landscape of FPD/AML revealed CDC25C mutation as a driver that promotes malignant transformation2013
    • Author(s)
      Yoshimi A, Toya T, Nakagawa M, Kawazu M, Nannya Y, Ichikawa M, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Mano H, Kurokawa M
    • Organizer
      The 55th ASH Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H
    • Organizer
      The 74th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Kyoto,Japan
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H, Inoue D, Ding Y, Imagawa J, Harada Y, Kitamura T
    • Organizer
      The 74th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] 放射線関連MDS・白血病の発症機序におけるRUNX1/AML1変異の役割「放射線障害と血液疾患」2012
    • Author(s)
      原田浩徳
    • Organizer
      第52回日本リンパ網内系学会総会
    • Place of Presentation
      福島
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] Molecular mechanisms of myelodysplastic syndromes by RUNX1/AML1 mutations2012
    • Author(s)
      Harada H
    • Organizer
      The 3rd JSH International Symposium in Kawagoe
    • Place of Presentation
      Kawagoe, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H
    • Organizer
      ISEH 41st Annual Scientific Meeting
    • Place of Presentation
      Amsterdam,Netherland
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] 造血器腫瘍におけるRUNX1, MLLキメラ遺伝子発生プロセスの解明2012
    • Author(s)
      原田浩徳, 原田結花
    • Organizer
      第16回造血器腫瘍研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanisms of myelodysplastic syndromes by RUNX1/AML1 mutations2012
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 3rd JSH International Symposium 2012 in Kawagoe
    • Place of Presentation
      Kawagoe, Japan
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes (MDS) / acute myeloid leukemia (AML) in a mouse BMT model2012
    • Author(s)
      Harada H, Inoue D, Doki N, Ding Y, Harada Y, Kitamura T
    • Organizer
      The 54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      ISEH 41st Annual Scientific Meeting
    • Place of Presentation
      Amsterdam, Netherland
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes.2012
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      The 71st Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H
    • Organizer
      ISEH 41st Annual Scientific Meeting
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] Impaired hematopoietic differentiation of iPSCs derived from a patient with FPD/AML2012
    • Author(s)
      Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Sadahira K, Yuasa S, Fukuda K, Yamazaki S, Nakauchi H, Ebihara Y, Tsuji K, Ito E, Harada Y, Harada H, Okamoto S, Nakajima H
    • Organizer
      The 54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes (MDS) / acute myeloid leukemia (AML) in a mouse BMT model2012
    • Author(s)
      Harada H
    • Organizer
      The 54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      ISEH 41st Annual Scientific Meeting
    • Place of Presentation
      Amsterdam (Netherland)
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] 放射線関連 MDS・白血病の発症機序における RUNX1/AML1 変異の役割「放射線障害と血液疾患」2012
    • Author(s)
      原田浩徳
    • Organizer
      第52回日本リンパ網内系学会総会
    • Place of Presentation
      福島
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      ISEH 41st Annual Scientific Meeting
    • Place of Presentation
      Amsterdam, Netherland
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] 放射線関連MDS・白血病の発症機序におけるRUNX1/AML1変異の役割「放射線障害と血液疾患」2012
    • Author(s)
      原田浩徳
    • Organizer
      第52回日本リンパ網内系学会総会
    • Place of Presentation
      福島
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H, Inoue D, Ding Y, Imagawa J, Harada Y, Kitamura T
    • Organizer
      The 74th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Molecular mechanisms of myelodysplastic syndromes by RUNX1/AML1 mutations2012
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 3rd JSH International Symposium 2012 in Kawagoe
    • Place of Presentation
      川越(埼玉)
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] Molecular mechanisms of myelodysplastic syndromes by RUNX1/AML1 mutations2012
    • Author(s)
      Harada H
    • Organizer
      The 3rd JSH International Symposium 2012
    • Place of Presentation
      Kawagoe, Japan
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes (MDS) / acute myeloid leukemia (AML) in a mouse BMT model2012
    • Author(s)
      Harada H
    • Organizer
      The 54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H, Harada Y, Inoue D, Kitamura T
    • Organizer
      The 71st Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] 放射線関連MDS・白血病の発症機序におけるRUNX1/AML1変異の役割「放射線障害と血液疾患」2012
    • Author(s)
      原田浩徳
    • Organizer
      第52回日本リンパ網内系学会総会
    • Place of Presentation
      福島
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] RUNX1変異を中心としたMDSの分子病態2012
    • Author(s)
      原田浩徳
    • Organizer
      血液腫瘍シンポジウム2012MDS～病態解析と治療の進歩～
    • Place of Presentation
      東京
    • Year and Date
      2012-03-03
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes (MDS) / acute myeloid leukemia (AML) in a mouse BMT model2012
    • Author(s)
      Harada H, Inoue D, Doki N, Ding Y, Harada Y, Kitamura T
    • Organizer
      The 54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] Molecular mechanisms of myelodysplastic syndromes by RUNX1/AML1 mutations2012
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 3rd JSH International Symposium 2012 in Kawagoe
    • Place of Presentation
      Kawagoe, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H
    • Organizer
      The 71st Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Sapporo,Japan
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] RUNX1/AML1 mutants collaborate with BMI1 in the development of myelodysplastic syndromes2012
    • Author(s)
      Harada H, Inoue D, Ding Y, Imagawa J, Harada Y, Kitamura T
    • Organizer
      The 74th Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] BMI1 collaborates with RUNX1/AML1 mutants in the development of human myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML)2011
    • Author(s)
      Harada H, Ding Y, Imagawa J, Miyama T, Kimura A, Harada Y
    • Organizer
      The 53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Molecular mechanism to produce myeloid neoplasms by RUNX1 or MLL chimeras in human CD34+ cells2011
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 18th International RUNX Workshop
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] BMI1 collaborates withRUNX1/ AML1 mutants in the development ofhuman myelodysplastic syndrome(MDS)/ acute myeloid leukemia(AML)2011
    • Author(s)
      Harada H, Ding Y, Imagawa J, Miyama T, Kimura A, Harada Y
    • Organizer
      53rd AnnualMeeting of the American Society ofHematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 放射線・化学療法関連骨髄系腫瘍の発症に関わるRUNX1/AML1遺伝子点突然変異2011
    • Author(s)
      原田結花, 木村昭郎, 原田浩徳
    • Organizer
      第52回原子爆弾後障害研究会
    • Place of Presentation
      広島市
    • Year and Date
      2011-06-05
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] 教育講演 MDS「分子病態」2011
    • Author(s)
      原田浩徳
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] The dynamic effect of dasatinib on largegranular lymphocyte expansion in Ph ALLpatient2011
    • Author(s)
      Imagawa J, Yoshida T, Mino T, Kimura A, Matsumoto K, Morita K, Harada Y, Harada H
    • Organizer
      73rd Annual Meeting of theJapanese Society of Hematology
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 放射線・化学療法関連骨髄系腫瘍の発症に関わる RUNX1/AML1 遺伝子点突然変異2011
    • Author(s)
      原田結花,木村昭郎,原田浩徳
    • Organizer
      第52回原子爆弾後障害研究会
    • Place of Presentation
      広島
    • Year and Date
      2011-06-05
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Molecular mechanisms thatproduce radiation-induced or therapyrelatedMDS/ AML by RUNX1/ AML1 pointmutations2011
    • Author(s)
      Harada H
    • Organizer
      The 6th InternationalSymposium of Nagasaki University GlobalCOE Program" Global Strategic Center forRadiation Health Risk Control
    • Place of Presentation
      Nagasaki
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanisms to produced myeloid neoplasms by RUNX1 or MLL chimeras in human CD34^+ cells2011
    • Author(s)
      Harada H, Ding Y, Kimura A, Harada Y
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 放射線・化学療法関連骨髄系腫瘍の発症に関わるRUNX1/ AML1遺伝子点突然変異2011
    • Author(s)
      原田結花, 木村昭郎, 原田浩徳
    • Organizer
      第52回原子爆弾後障害研究会
    • Place of Presentation
      広島
    • Year and Date
      2011-06-05
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Long-term follow up data of cytogenetic response in Japanese low/lnt-1 MDS patients with del(5q)2011
    • Author(s)
      Taniwaki M, Chinen Y, Harada H, Watanabe M, Suzuki K, Yanagida S, Shimada H, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Matsuda A, Tohyama K, Takatoku M, Ozawa K
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] The dynamic effect of dasatinib on large granular lymphocyte expansion in Ph ALL patient2011
    • Author(s)
      Imagawa J, Yoshida T, Mino T, Kimura A, Matsumoto K, Morita K, Harada Y, Harada H
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Deferasirox improved cytopenia inpatients with bone marrow failure2011
    • Author(s)
      Harada Y, Okikawa Y, Kimura A, Ito T, Niimi H, Noda M, Tanaka H, Shimomura T, Kuroda Y, Katsutani S, Kimura A, Harada H
    • Organizer
      73rdAnnual Meeting of the Japanese Society ofHematology
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanisms to produced myeloid neoplasms by RUNX1 or MLL chimeras in human CD34+ cells2011
    • Author(s)
      Harada H, Ding Y, Kimura A, Harada Y
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Expansion of CD8^+/perforin^+ T-cell subset in patients predicts response to cyclosporin a therapy in patients with erythroid hypoplasia/aplasia2011
    • Author(s)
      Nitta H, Harada Y, Hyodo H, Kimura A, Harada H
    • Organizer
      The 53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Myelodysplastic syndrome with pure redcell aplasia, clinical new entity2011
    • Author(s)
      Nitta H, Harada Y, Kimura A, Harada H
    • Organizer
      73rdAnnual Meeting of the Japanese Society ofHematolog
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Deferasirox improved cytopenia in patients with bone marrow failure2011
    • Author(s)
      Harada Y, Okikawa Y, Kimura A, Ito T, Niimi H, Noda M, Tanaka H, Shimomura T, Kuroda Y, Katsutani S, Kimura A, Harada H
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanisms that produce radiation-induced or therapyrelated MDS/AML by RUNX1/AML1 point mutaions2011
    • Author(s)
      Harada H
    • Organizer
      The 6th International Symposium of Nagasaki University Global COE Program
    • Place of Presentation
      長崎
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] Clinical and Genetic Features of Therapy-Related Myeloid Neoplasms after Chemotherapy for Acute Promyelocy ticleukemia.2011
    • Author(s)
      Imagawa J, Harada Y, Kimura A, Harada H
    • Organizer
      The 2nd JSH International Symposium 2011 in Nagasaki
    • Place of Presentation
      Nagasaki
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] BMI1 collaborates with RUNX1/AML1 mutants in the development of human myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML)2011
    • Author(s)
      Harada H, Ding Y, Imagawa J, Miyama T, Kimura A, Harada Y
    • Organizer
      The 53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanisms that produce radiation-induced or therapy-related MDS/AML by RUNX1/AML1 point mutaions2011
    • Author(s)
      Harada H
    • Organizer
      The 6^<th> International Symposium of Nagasaki University Global COE Program
    • Place of Presentation
      Nagasaki, Japan(Invited)
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Clinical and genetic features of therapy-related myeloid neoplasms after chemotherapy for acute promyelocytic leukemia2011
    • Author(s)
      Imagawa J, Harada Y, Kimura A, Harada H
    • Organizer
      The 2nd JSH International Symposium
    • Place of Presentation
      Nagasaki, Japan
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] 放射線・化学療法関連骨髄系腫瘍の発症に関わるRUNX1/AML1遺伝子点突然変異2011
    • Author(s)
      原田結花, 木村昭郎, 原田浩徳
    • Organizer
      第52回原子爆弾後障害研究会
    • Place of Presentation
      広島市
    • Year and Date
      2011-06-05
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 教育講演MDS「分子病態」2011
    • Author(s)
      原田浩徳
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanism to produce myeloid neoplasms by RUNX1 or MLL chimeras in human CD34^+ cells2011
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 18^<th> International RUNX Workshop
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] BMI1 collaborates with RUNX1/AML1 mutants in the development of human myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML)2011
    • Author(s)
      Harada H, Ding Y, ImagawaJ, Miyama T, Kimura A, Harada Y
    • Organizer
      The 53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] The dynamic effect of dasatinib on large granular lymphocyte expansion in Ph ALL patient2011
    • Author(s)
      Imagawa J, Yoshida T, Mino T, Kimura A, Matsumoto K, Morita K, Harada Y, Harada H
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Expansion of CD8^+/perform^+ T-cell subset in patients predicts response to cyclosporin a therapy in patients with erythroid hypoplasia/aplasia2011
    • Author(s)
      Nitta H, Harada Y, Hyodo H, Kitnura A, Harada H
    • Organizer
      The 53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] RUNX1変異によるMDSの分子発症メカニズム2011
    • Author(s)
      原田浩徳
    • Organizer
      2011新学術領域細胞運命制御班会議
    • Place of Presentation
      軽井沢
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanisms to produced myeloidneoplasms by RUNX1 or MLL chimeras in humanCD34+ cells2011
    • Author(s)
      Harada H, Ding Y, Kimura A, Harada Y
    • Organizer
      73rd Annual Meeting of theJapanese Society of Hematology
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Long-term follow up data of cytogeneticresponse in Japanese low/ lnt-1 MDSpatients with del(5q)2011
    • Author(s)
      Taniwaki M, Chinen Y, Harada H, Watanabe M, Suzuki K, Yanagida S, ShimadaH, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Matsuda A, Tohyama K, Takatoku M, Ozawa K
    • Organizer
      The 73rd AnnualMeeting of the Japanese Society ofHematology
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 放射線・化学療法関連骨髄系腫瘍の発症に関わるRUNX1/AML1遺伝子点突然変異2011
    • Author(s)
      原田結花、木村昭郎、原田浩徳
    • Organizer
      第52回原子爆弾後障害研究会
    • Place of Presentation
      広島市
    • Year and Date
      2011-06-05
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] Molecular mechanisms that produce radiation-induced or therapy-related MDS/AML by RUNX1/AML1 point mutaions2011
    • Author(s)
      Harada H
    • Organizer
      The 6^<th> International Symposium of Nagasaki University Global COE Program
    • Place of Presentation
      Nagasaki, Japan(Invited)
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] 骨髄異形成症候群(MDS)の最近の知見～発症機序と治療を中心に～2011
    • Author(s)
      原田浩徳
    • Organizer
      第165回福岡血液懇話会
    • Place of Presentation
      福岡
    • Year and Date
      2011-07-08
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Expansion of CD8+/ perforin+ T-cell subset in patients predictsresponse to cyclosporin a therapy inpatients with erythroid hypoplasia/ aplasia2011
    • Author(s)
      Nitta H, Harada Y, Hyodo H, Kimura A, Harada H
    • Organizer
      53rd Annual Meeting of theAmerican Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Clinical and genetic features of therapy-related myeloid neoplasms after chemotherapy for acute promyelocytic leukemia2011
    • Author(s)
      Imagawa J, Harada Y, Kimura A, Harada H
    • Organizer
      The 2^<nd> JSH International Symposium
    • Place of Presentation
      Nagasaki, Japan
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecularmechanism to produce myeloid neoplasms byRUNX1 or MLL chimeras in human CD34+ cells2011
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 18th International RUNX Workshop
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] BMI1 collaborates with RUNX1/AML1 mutants in the development of human myelodysplastic syndrome (MDS) / acute myeloid leukemia (AML)2011
    • Author(s)
      Harada H, Ding Y, Imagawa J, Miyama T, Kimura A, Harada Y
    • Organizer
      The 53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] 造血器腫瘍における RUNX1,MLL キメラ遺伝子発生プロセスの解明2011
    • Author(s)
      原田浩徳,丁 曄,木村昭郎,原田結花
    • Organizer
      造血器腫瘍における RUNX1,MLL キメラ遺伝子発生プロセスの解明
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Molecular mechanism to produce myeloid neoplasms by RUNX1 or MLL chimeras in human CD34+ cells2011
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 18^<th> International RUNX Workshop
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] BMI1 Collaborates with RUNX1/AML1 Mutants in the Development of Human Myelodysplastic Syndrome (MDS) / Acute Myeloid Leukemia (AML)2011
    • Author(s)
      Harada H, Ding Y, Imagawa J, Miyama T, Kimura A, Harada Y
    • Organizer
      The 53rd ASH Annual Meeting
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Molecular mechanism to produce myeloid neoplasms by RUNX1 or MLL chimeras in human CD34^+ cells2011
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 18^<th> International RUNX Workshop
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23310183

  • [Presentation] Myelodysplastic syndrome with pure red cell aplasia, clinical new entity2011
    • Author(s)
      Nitta H, Harada Y, Kimura A, Harada H
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] RUNX1のC末部変異体によるMDS/ AML分子発症機構2011
    • Author(s)
      原田浩徳
    • Organizer
      第7回広島大学・長崎大学連携研究事業カンファランス
    • Place of Presentation
      広島
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Myelodysplastic syndrome with pure red cell aplasia, clinical new entity2011
    • Author(s)
      Nitta H, Harada Y, Kimura A, Harada H
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Deferasirox improved cytopenia in patients with bone marrow failure2011
    • Author(s)
      Harada Y, Okikawa Y, Kimura A, Ito T, Niimi H, Noda M, Tanaka H, Shimomura T, Kuroda Y, Katsutani S, Kimura A, Harada H
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] 放射線関連 MDS・白血病の発症機序における AML1点突然変異の役割2010
    • Author(s)
      原田浩徳
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Deferasirox improved severe cardiac insufficiency and pancytopenia in a patient with aplastic anemia2010
    • Author(s)
      Harada Y, Harada H, Imagawa J, Kimura A
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Molecular mechanisms to produce MDS/AML by C-terminal trancated type of AML1/RUNX1 mutations2010
    • Author(s)
      Harada H, Harada Y, Imagawa J, Kimura A
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 骨髄増殖性腫瘍からの白血病移行メカニズムの解明2010
    • Author(s)
      丁 曄,原田結花,今川 潤,木村昭郎,原田浩徳
    • Organizer
      第107回日本内科学会講演会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-10
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] 放射線関連MDS・白血病の発症機序におけるAML1点突然変異の役割.2010
    • Author(s)
      原田浩徳
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanisms to produce MDS/AML by C-terminal trancated type of AML1/RUNX1 mutations2010
    • Author(s)
      Harada H, Harada Y, Imagawa J, Kimura A
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] Molecular mechanisms to produce MDS/ AMLby C-terminal trancated type of AML1/ RUNX1mutations.2010
    • Author(s)
      Harada H, Harada Y, Imagawa J, Kimura A
    • Organizer
      72nd Annual Meeting of JapaneseSociety of Hematology
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 放射線関連MDS・白血病の発症機序におけるAML1点突然変異の役割2010
    • Author(s)
      原田浩徳
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] A caseof FPD/ AML with a novel RUNX1 mutation2010
    • Author(s)
      Sakurai M, Watanabe N, Harada H, HaradaY, Sadahira K, Fukuchi Y, Tsukada Y, Yokoyama K, Okamoto S, Nakajima H
    • Organizer
      72nd Annual Meeting of Japanese Society of Hematology
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] A vaginalgiant granulocytic sarcoma concurrentlywith acute myeloid leukemia witht(8 ; 21)(q22 ; q22).2010
    • Author(s)
      Imagawa J, Harada H, Yoshida T, SakaiA, Harada Y, Sasaki N, Kimura A
    • Organizer
      72nd Annual Meeting ofJapanese Society of Hematology
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanism to produce MDS/AML by C-terminal truncated type of AML1/RUNX1 mutations2010
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 17^<th> international RUNX workshop
    • Place of Presentation
      Hiroshima
    • Year and Date
      2010-07-14
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecular mechanism to produce MDS/AML by C-terminal truncated type of AML1/RUNX1 mutations2010
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 17th international RUNX workshop
    • Place of Presentation
      Hiroshima
    • Year and Date
      2010-07-14
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] A case of FPD/AML with a novel RUNX1 mutation2010
    • Author(s)
      Sakurai M, Watanabe N, Harada H, Harada Y, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 骨髄増殖性腫瘍からの白血病移行メカニズムの解明2010
    • Author(s)
      丁曄, 原田結花, 今川潤, 木村昭郎, 原田浩徳
    • Organizer
      第107回日本内科学会講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Deferasirox improved severe cardiacinsufficiency and pancytopenia in apatient with aplastic anemia2010
    • Author(s)
      Harada Y, Harada H, Imagawa J, KimuraA
    • Organizer
      72nd AnnualMeeting of Japanese Society of Hematology
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Deferasirox improved severe cardiac insufficiency and pancytopenia in a patient with aplastic anemia2010
    • Author(s)
      Harada Y, Harada H, Imagawa J, Kimura A
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] A vaginal giant granulocytic sarcoma concurrently with acut emyeloid leukemia with t(8;21)(q22;q22)2010
    • Author(s)
      Imagawa J, Harada H, Harada Y, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] A case of FPD/AML with a novel RUNX1 mutation2010
    • Author(s)
      Sakurai M, Watanabe N, Harada H, Harada Y, Sadahira K, Fukuchi Y, Tsukada Y, Yokoyama K, Okamoto S, Nakajima H
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] 慢性骨髄増殖性腫瘍からの白血病移行メカニズムの解明2010
    • Author(s)
      丁曄, 原田結花, 原田浩徳
    • Organizer
      第6回麒麟塾
    • Place of Presentation
      東京
    • Year and Date
      2010-06-05
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Successful 2nd CBT using minimalconditioning regimens for patients withprimary graft failure2010
    • Author(s)
      Okikawa Y, Kuroda Y, Ito T, Niimi H, Harada H
    • Organizer
      72nd Annual Meetingof Japanese Society of Hematology
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Molecularmechanism to produce MDS/ AML by C-terminal truncated type of AML1/ RUNX1 mutations.2010
    • Author(s)
      Harada H, Harada Y
    • Organizer
      The 17th International RUNX Workshop
    • Place of Presentation
      Hiroshima
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 慢性骨髄増殖性腫瘍からの白血病移行メカニズムの解明2010
    • Author(s)
      丁 曄,原田結花,原田浩徳
    • Organizer
      第6回麒麟塾
    • Place of Presentation
      東京
    • Year and Date
      2010-06-05
    • Data Source
      KAKENHI-PROJECT-22591038

  • [Presentation] A vaginal giant granulocytic sarcoma concurrently with acute myeloid leukemia with t(8;21)(q22;q22)2010
    • Author(s)
      Imagawa J, Harada H, Harada Y, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 日本人の骨髄異形成症候群(MDS)患者を対象としたlenalidomideの第II相臨床試験成績2009
    • Author(s)
      渡邊光正, 通堂満, 鈴木憲史, 原田浩徳, 木村昭郎, 柳田宗之, 鈴木隆浩, 吉田彌太郎, 高徳正昭, 小澤敬也
    • Organizer
      第106回日本内科学会講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Results ofPhase II Clinical Study of Lenalidomide in Japanese Patients with Myelodysplastic Syndrome(MDS)2009
    • Author(s)
      Harada H, Watanabe M, Suzuki K, Yanagita S, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Takatoku M, Ozawa K
    • Organizer
      The 10th InternationalSymposium on Myelodysplastic Syndromes(MDS2009)
    • Place of Presentation
      Patras, Greece
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] RUNX1 controls nucleotideexcision repair(NER) throughtran scriptional regulation of Gadd45a.2009
    • Author(s)
      Satoh Y, Matsumura I, Harada H, Kanakura Y
    • Organizer
      68th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Analysis of C/ EBPA mutationsin AML, MDS by a mouse BMT model2009
    • Author(s)
      Kato N, Komeno Y, Watanabe N, NakaharaF, Doki N, Harada H, Harada Y, Kitaura J, Kitamura T
    • Organizer
      71stAnnual Meeting of Japanese Society of Hematology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Lenalidomide inJapanese Patients with Symptomatic anemiain Low or Int-1 Risk MDS with deletion 5q.2009
    • Author(s)
      Watanabe M, Harada H, Suzuki K, Yanagita S, Suzuki T, Yoshida Y, Tsudo M, Kimura A, Matsuda A, Tohyama K, TaniwakiM, Takatoku M, Ozawa K
    • Organizer
      71st Annual Meeting of Japanese Society of Hematology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Two different AML1mutants expressed in human CD34+ cellsexhibit distinct molecular pathways andclinical features of MDS/ AML2009
    • Author(s)
      Harada H, Harada Y
    • Organizer
      EMBO Workshop(16th RUNX Meeting)
    • Place of Presentation
      Oxford, UK
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Two different AML1 mutants expressed in human CD34^+ cells exhibit distinct molecular pathways and clinical features of MDS/AML2009
    • Author(s)
      Harada H, Ding Y, Harada Y
    • Organizer
      RUNX Transcription Factors in Development & Diseases
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2009-08-19
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] AML1/ RUNX1point mutation possibly promotes leukemictrans for mation in chronic myeloproliferativedisorders2009
    • Author(s)
      Harada Y, Ding Y, Harada H
    • Organizer
      EMBO Workshop(16th RUNX Meeting)
    • Place of Presentation
      Oxford, UK
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Distinct molecular pathways andclinical features of MDS/ AML by twodifferent AML1 mutants.2009
    • Author(s)
      Harada H, Harada Y, Imagawa J, Kimura A
    • Organizer
      71st Annual Meeting of Japanese Society of Hematology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] AML1/RUNX1 point mutation possibly promotes leukemic transformation in chronic myeloproliferative disorders2009
    • Author(s)
      Imagawa J, Harada Y, Ding Y, Kimura A, Harada H
    • Organizer
      51st American Society of Hematology annual meeting
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] C-terminalmutation of RUNX1 deteriorates DNAdamage-repair response and promotes thedevelopment of acute myeloid leukemia2009
    • Author(s)
      Satoh Y, Matsumura I, Tanaka H, HaradaH, Harada Y, Kanakura Y
    • Organizer
      51st American Society of Hematology annualmeeting
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] 日本人の骨髄異形成症候群(MDS)患者を対象とした lenalidomide の第II相臨床試験成績2009
    • Author(s)
      渡邊光正, 通堂満, 鈴木憲史, 原田浩徳, 他
    • Organizer
      第106回日本内科学会講演会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-10
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] AML1/ RUNX1 point mutationpossibly promotes leukemic transformationin chronic myeloproliferative disorders2009
    • Author(s)
      Imagawa J, Harada Y, Ding Y, Kimura A, Harada H
    • Organizer
      51st American Society of Hematology annualmeeting
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Effects of radiation onhematopoietic organ. Myelodysplasticsyndrome caused by radiation after longlatency period2009
    • Author(s)
      Harada H
    • Organizer
      International Workshop on Chernobyl Health Consequences
    • Place of Presentation
      Kiev, Ukraine
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Analysis of C/EBPA mutations in AML, MDS by a mouse BMT model2009
    • Author(s)
      Kato N, Komeno Y, Watanabe N, Nakahara F, Doki N, Harada H, Harada Y, Kitaura J, Kitamura T
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] RUNX1 controls nucleotide excision repair(NER) throughtranscriptional regulation of Gadd45a.2009
    • Author(s)
      Satoh Y, Matsumura I, Harada H, HaradaY, Kanakura Y
    • Organizer
      71st Annual Meeting of Japanese Society of Hematology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Effects of radiation on hematopoietic organ-Myelodysplastic syndrome caused by radiation after long latency period2009
    • Author(s)
      原田浩徳
    • Organizer
      International Workshop on Chernobyl Health Consequences
    • Place of Presentation
      Kiev, Ukraine
    • Year and Date
      2009-12-15
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] AML1/RUNX1 point mutation possibly promotes leukemic transformation in chronic myeloproliferative disorders2009
    • Author(s)
      Harada Y, Ding Y, Harada H
    • Organizer
      RUNX Transcription Factors in Development & Diseases
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2009-08-19
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Distinct molecular pathways and clinical features of MDS/AML by two different AML1 mutants2009
    • Author(s)
      原田浩徳, 原田結花, 今川潤, 木村昭郎
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Results of Phase II Clinical Study of Lenalidomide in Japanese Patients with Myelodysplastic Syndrome (MDS)2009
    • Author(s)
      原田浩徳
    • Organizer
      CC-5013-MDS-007研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-05-16
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] RUNX1 controls nucleotide excision repair (NER) through transcriptional regulation of Gadd45a2009
    • Author(s)
      Satoh Y, Matsumura I, Harada H, Harada Y, Kanakura Y
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] RUNX1 controls nucleotide excision repair (NER) through transcriptional regulation of Gadd45a2009
    • Author(s)
      Satoh Y, Matsumura I, Harada H, Kanakura Y
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] C/ EBPα変異パターンによる急性骨髄性白血病(AML)および骨髄異形成症候群(MDS)病型の解析2009
    • Author(s)
      原田浩徳, 今川潤, 原田結花, 木村昭郎
    • Organizer
      第50回原子爆弾後障害研究会
    • Place of Presentation
      広島
    • Year and Date
      2009-06-07
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] AML mutation in AML/MDS2009
    • Author(s)
      Harada H
    • Organizer
      6^<th> KSH AML/MDS Working Party Symposium & 3^<rd> Korea-Japan Joint Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-03-14
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] AML1 mutation in AML/MDS. 6^<th> Korean Society of Hematology AML/MDS Working Party Symposium2009
    • Author(s)
      Harada H
    • Organizer
      3^<rd> Korea-Japan Joint Symposium on Molecular Targets and AML/MDS Therapeutics
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-03-14
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] C-terminal mutation of RUNX1 deteriorates DNA damage-repair response and promotes the development of acute myeloid leukemia2009
    • Author(s)
      Satoh Y, Matsumura I, Tanaka H, Harada H, Harada Y, Kanakura Y
    • Organizer
      51st American Society of Hematology annual meeting
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Results of Phase II Clinical Study of Lenalidomide in Japanese Patients with Myelodysplastic Syndrome (MDS)2009
    • Author(s)
      原田浩徳
    • Organizer
      The 10^<th> International Symposium on Myelodysplastic Syndromes (MDS2009)
    • Place of Presentation
      Patras, Greece
    • Year and Date
      2009-05-08
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] Lenalidomide in Japanese Patients with Symptomatic anemia in Low or Int-1 Risk MDS with deletion 5q2009
    • Author(s)
      渡邊光正, 原田浩徳
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21591206

  • [Presentation] AML1/RUNX1点変異によるMDS/AML多段階発症機構2008
    • Author(s)
      丁曄, 原田浩徳, 原田結花, 今川潤, 許泰一, 木村昭郎
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] Distinct molecular pathways and clinical features of MDS/AML by 2 types of AML1/RUNX1 mutations2008
    • Author(s)
      Harada H, et al.
    • Organizer
      15^<th> International RUNX Workshop
    • Place of Presentation
      Provincetown, MA, USA
    • Year and Date
      2008-09-16
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] AML, MDSでみられたC/EBPα変異体のマウスBMTモデルによる解析2008
    • Author(s)
      加藤菜穂子, 米野由希子, 渡辺(大河内)直子, 原田浩徳, 原田結花, 北浦次郎, 北村俊雄
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] 慢性骨髄増殖性疾患からの白血病移行メカニズムの解明2008
    • Author(s)
      今川潤, 原田浩徳, 原田結花, 丁曄, 兵頭英出夫, 木村昭郎
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-12
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] マウス骨髄移植モデルにおいて、Evi1はMDS/AMLを誘発する2008
    • Author(s)
      渡辺(大河内)直子, 北浦次郎, 原田浩徳, 米野由希子, 加藤菜穂子, 小埜良一, 野阪哲哉, 中島秀明, 北村俊雄
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] Distinct molecular pathways and clinical features of MDS/AML by 2 types of AML1/RUNX1 mutations2008
    • Author(s)
      Harada H, Ding Y, Harada Y
    • Organizer
      15^<th> International RUNX Workshop
    • Place of Presentation
      Provincetown, USA
    • Year and Date
      2008-09-16
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] AML1/RUNX1点変異部位によるMDS/AML発症機構の相違と新たな病型分類2008
    • Author(s)
      原田浩徳, 原田結花, 丁曄, 今川潤, 許泰一, 木村昭郎
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] High incidence of AML1 point mutations in myelodysplastic syndrome among residents of the Semipalatinsk Nuclear Test Site2008
    • Author(s)
      Zharlyganova D, Harada Y, Harada H, Zhumadilov Z, Zhunussova A, Chaizhunussova N, Shinkarev S, Kimura A, Hoshi M
    • Organizer
      The Fifth International Symposium of Hiroshima University 21st Century COE program
    • Place of Presentation
      Hiroshima, Japan
    • Year and Date
      2008-01-24
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] C/EBPα変異パターンによる急性骨髄性白血病および骨髄異形成症候群の病型解析2008
    • Author(s)
      今川潤, 原田浩徳, 原田結花, 丁曄, 木村昭郎
    • Organizer
      第105回日本内科学会講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-04-11
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] セミパラチンスク核実験場近郊住民における骨髄異形成症候群(MDS)の遺伝子学的検討2007
    • Author(s)
      Zharlyganova D, 原田結花, 原田浩徳, Chaizhunussova N , Apsalikov K, Zhunussova A, 川野徳幸, 星正治, 木村昭郎
    • Organizer
      第48回原子爆弾後障害研究会
    • Place of Presentation
      広島
    • Year and Date
      2007-06-03
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] C/EBPα変異パターンによるAMLおよびMDS病型の解析2007
    • Author(s)
      原田浩徳, 他
    • Organizer
      第69回日本血液学会総会・第49回日本臨床血液学会合同総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Presentation] RasGRP4と変異型AML1はマウスBMT モデルにおいて協調的に働き, T 細胞性白血病を誘発する2007
    • Author(s)
      渡辺(大河内)直子, 沖俊彦, 小埜良一, 原田浩徳, 湯池晃一郎, 東條有伸, 中島秀明, 野阪哲哉, 稲葉俊哉, 北浦次郎, 北村俊雄
    • Organizer
      第69回日本血液学会総会・第49回日本臨床血液学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] AML1点変異をマスターイベントとするMDS/AML発症機構の解明2007
    • Author(s)
      丁曄, 原田浩徳, 原田結花, 木村昭郎
    • Organizer
      第69回日本血液学会総会・第49回日本臨床血液学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] AML1/RUNX1 point mutation plays a pivotal role in the pathogenesis of MDS/AML2007
    • Author(s)
      Ding Y, Harada Y, Harada H
    • Organizer
      RUNX 2007(14^<th> RUNX Meeting)
    • Place of Presentation
      Singapore
    • Year and Date
      2007-08-20
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] CEBPA point mutations in acute myeloid leukemia and myelodysplastic syndrome2007
    • Author(s)
      Harada, H., et. al.
    • Organizer
      69th Annual Meeting of Japanese Society of Hematology 49th Annual Meeting of Japanese Society of Clinical Hematology
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591063

  • [Presentation] C/EBPα変異パターンによるAMLおよびMDS病型の解析2007
    • Author(s)
      原田浩徳, 原田結花, 丁曄, 許泰一, 木村昭郎
    • Organizer
      第69回日本血液学会総会・第49回日本臨床血液学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591114

  • [Presentation] A randamized study to determine the opitimal dose of darbepoetin alfa in patients with low- or intermediate-1 risk myelodysplastic syndromes
    • Author(s)
      Harada H, Shibayama H, Jang JH, Shimazaki R, Mitani K, Sawada K, Kim H-J
    • Organizer
      The 56th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2014-12-06 – 2014-12-09
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] Impaired platelet function in FPD/AML patients
    • Author(s)
      Sakurai M, Watanabe N, Kunimoto H, Fukuchi Y, Sadahira K, Abe D, Soma S, Ito E, Harada Y, Harada H, Okamoto S, Nakajima H
    • Organizer
      The 76th Annual Meetingof the Japanese Society of Hematology
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] 機能獲得型RUNX1変異による骨髄異形成症候群の発症機序
    • Author(s)
      原田浩徳
    • Organizer
      第19回造血器腫瘍研究会
    • Place of Presentation
      グランテはがくれ（佐賀県佐賀市）
    • Year and Date
      2015-01-23 – 2015-01-24
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] Recurrent CDC25C mutations drive malignant transformation in FPD/AML
    • Author(s)
      Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, Nakagawa M, Nannya Y, Arai S, Ichikawa M, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Mano H, Kurokawa M
    • Organizer
      AACR Annual Meeting 2014
    • Place of Presentation
      SanDiego, (USA)
    • Year and Date
      2014-04-04 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] 機能獲得型RUNX1変異による骨髄異形成症候群の発症機序
    • Author(s)
      原田浩徳
    • Organizer
      2014新学術領域細胞運命制御班会議
    • Place of Presentation
      東京大学医科学研究所講堂（東京都港区）
    • Year and Date
      2014-09-02 – 2014-09-04
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] 機能獲得型RUNX1変異による骨髄異形成症候群の発症機序
    • Author(s)
      原田浩徳
    • Organizer
      2014新学術領域細胞運命制御班会議
    • Place of Presentation
      東京大学医科学研究所講堂（東京都港区）
    • Year and Date
      2014-09-02 – 2014-09-04
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] 機能獲得型RUNX1変異による骨髄異形成症候群の発症機序
    • Author(s)
      原田浩徳
    • Organizer
      第19回造血器腫瘍研究会
    • Place of Presentation
      佐賀
    • Year and Date
      2015-01-21 – 2015-01-23
    • Data Source
      KAKENHI-PROJECT-24249039

  • [Presentation] Impaired platelet function in FPD/AML patients
    • Author(s)
      Sakurai M, Watanabe N, Kunimoto H, Fukuchi Y, Sadahira K, Abe D, Soma S, Ito E, Harada Y, Harada H, Okamoto S, Nakajima H
    • Organizer
      The 76th Annual Meetingof the Japanese Society of Hematology
    • Place of Presentation
      大阪国際会議場（大阪市北区）
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-24591398

  • [Presentation] C-terminal truncation type of RUNX1 mutants induce MDS/AML via gain-of-function mechanisms
    • Author(s)
      Harada H, Harada Y, Inoue D, Ding Y, Sashida G, Iwama A, Nakajima H, Tanaka J, KomatsuN, Kitamura T
    • Organizer
      The 76th Annual Meetingof the Japanese Society of Hematology
    • Place of Presentation
      大阪国際会議場（大阪市北区）
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-25461422

  • [Presentation] 骨髄異形成症候群の分子病態と治療
    • Author(s)
      原田浩徳
    • Organizer
      第12回日本臨床腫瘍学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2014-07-17 – 2014-07-19
    • Data Source
      KAKENHI-PROJECT-26257501