Endo Jin 遠藤仁

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ENDO JIN 遠藤仁

遠藤仁エンドウジン

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Researcher Number	50398608
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 慶應義塾大学, 医学部(信濃町), 講師 2018: 慶應義塾大学, 医学部(信濃町), 専任講師(学部内) 2014 – 2015: 慶應義塾大学, 医学部, 助教 2005 – 2006: 慶應義塾大学, 医学部, 嘱託(非常勤)
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 53020:Cardiology-related / Basic Section 52010:General internal medicine-related / Cardiovascular medicine / Circulatory organs internal medicine Except Principal Investigator Cardiovascular medicine
Keywords	Principal Investigator マルチオミックス解析 / 心アミロイドーシス / 手根管症候群 / 野生型トランスサイレチンアミロイドーシス / 心毒性 / ドキソルビシン / GPX4 / ドキソルビシン心筋傷害 / ミトコンドリア / フェロトーシス … More / MARCH5 / Ｗｎｔシグナル / オートファジー / Wntシグナル / 早熟分化 / 細胞融合 / YAPシグナル / プロレニン受容体 / Wnt-βカテニンシグナル / 老化 / サルコペニア / ω-３脂肪酸 / 脂肪毒性 / 受容体探索 / リピドミクス / 骨髄由来細胞 / 心臓リモデリング / 脂肪酸 / 循環器・高血圧 / 再生医学 … More Except Principal Investigator 脂肪組織 / マクロファージ / 抗体治療 / 脂肪細胞 / 肥満 / インスリン抵抗性 / T細胞 / 炎症 / 免疫老化 Less

Elucidation of the pathogenic mechanism of ATTRwt amyloidosisPrincipal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Keio University
Elucidation of the cardioprotection mechanism mediated by mitochondrial regulatory proteinsPrincipal Investigator
- Principal Investigator
  
  Endo Jin
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Keio University
Elucidation of novel molecular mechanism of sarcopeniaPrincipal Investigator
- Principal Investigator
  
  Endo Jin
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Keio University
An investigation of the imapacts of tissue fatty acid balance control in cardiovascular diseasesPrincipal Investigator
- Principal Investigator
  
  Endo Jin
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Keio University
Amelioration of adipose inflammation and insulin resistance in aged and diet-induced obese mice by targeting programmed death-1+ adipose T cells
- Principal Investigator
  
  Shinmura Ken
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Hyogo Medical University
  Keio University
骨髄osteoblastic-zoneにおける多能性幹細胞の心筋分化の解析Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University

All 2023 2022 2021 2020 2019 2018 2016 2015 2014

All Journal Article Presentation Book

[Book] 医学のあゆみ「フェロトーシスにおけるミトコンドリア蛋白質 MITOLの新たな可能性」2023
- Author(s)
  北方博規、遠藤仁
- Total Pages
  2
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-21K08134
[Book] 代謝異常治療研究基金研究業績集　第41集20142015
- Author(s)
  新村　健、閂小響、白川公亮、玉城香代子、遠藤　仁、佐野元昭、福田恵一。
- Total Pages
  15
- Publisher
  一般社団法人　代謝異常治療研究基金
- Data Source
  KAKENHI-PROJECT-25461116
[Journal Article] MRP1-Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia-Reperfusion2023
- Author(s)
  Genki Ichihara, Yoshinori Katsumata, Yuki Sugiura, Yuta Matsuoka, Rae Maeda, Jin Endo, Atsushi Anzai, Kohsuke Shirakawa, Hidenori Moriyama, Hiroki Kitakata, Takahiro Hiraide, Shinichi Goto, Seien Ko, Yuji Iwasawa, Kazuhisa Sugai, Kyohei Daigo, Shinya Goto, Kazuki Sato, Ken-Ichi Yamada, Makoto Suematsu, et al.
- Journal Title
  
  Circulation Research
  
  Volume: 133 Issue: 10 Pages: 861-876
- DOI
  10.1161/circresaha.123.323517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1944, KAKENHI-PROJECT-23K06080, KAKENHI-PROJECT-21K08038, KAKENHI-PROJECT-21K08134, KAKENHI-PUBLICLY-22H05572, KAKENHI-PROJECT-23H05481, KAKENHI-PROJECT-19H03661, KAKENHI-PROJECT-23K27684
[Journal Article] Therapeutic Targets for DOX-Induced Cardiomyopathy: Role of Apoptosis vs. Ferroptosis2022
- Author(s)
  Hiroki Kitakata, Jin Endo, Hidehiko Ikura, Hidenori Moriyama, Kohsuke Shirakawa, Yoshinori Katsumata, Motoaki Sano
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23(3) Issue: 3 Pages: 1414-1414
- DOI
  10.3390/ijms23031414
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08134, KAKENHI-PROJECT-21K08038, KAKENHI-PROJECT-19K17579
[Journal Article] MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis2021
- Author(s)
  Kitakata Hiroki、Endo Jin、Matsushima Hirokazu、Yamamoto Shoichi、Ikura Hidehiko、Hirai Akeo、Koh Seien、Ichihara Genki、Hiraide Takahiro、Moriyama Hidenori et al.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 161 Pages: 116-129
- DOI
  10.1016/j.yjmcc.2021.08.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08134, KAKENHI-PROJECT-19K16527, KAKENHI-PROJECT-21K08038, KAKENHI-PROJECT-19K17579
[Journal Article] (Pro)renin receptor accelerates development of sarcopenia via activation of Wnt/YAP signaling axis2019
- Author(s)
  Yoshida Naohiro、Endo Jin、Kinouchi Kenichiro、Kitakata Hiroki、Moriyama Hidenori、Kataoka Masaharu、Yamamoto Tsunehisa、Shirakawa Kohsuke、Morimoto Satoshi、Nishiyama Akira、Hashiguchi Akihiro、Higuchi Itsuro、Fukuda Keiichi、Ichihara Atsuhiro、Sano Motoaki
- Journal Title
  
  Aging Cell
  
  Volume: 18 Issue: 5
- DOI
  10.1111/acel.12991
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07423, KAKENHI-PROJECT-19K16994, KAKENHI-PROJECT-18H02812
[Journal Article] Cardioprotective mechanism of omega-3 polyunsaturated fatty acids.2016
- Author(s)
  Endo J, Arita M
- Journal Title
  
  J Cardiol.
  
  Volume: 67 Pages: 22-27
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860586
[Journal Article] Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia/reperfusion.2016
- Author(s)
  Yamamoto T, Tamaki K, Shirakawa K, Ito K, Yan X, Katsumata Y, Anzai A, Matsuhashi T, Endo J, Inaba T, Tsubota K, Sano M, Fukuda K, Shinmura K,
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 310 Issue: 8 Pages: H1003-H1014
- DOI
  10.1152/ajpheart.00676.2015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461116
[Journal Article] 18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling.2014
- Author(s)
  Endo J, Sano M, Isobe Y, Fukuda K, Kang JX, Arai H, Arita M.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 211 Issue: 8 Pages: 673-1687
- DOI
  10.1084/jem.20132011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116006, KAKENHI-PROJECT-26860034, KAKENHI-PROJECT-26860586, KAKENHI-PROJECT-23227004
[Presentation] Elucidation of novel molecular mechanism of sarcopenia via (pro)renin receptor-Wnt/YAP signaling pathway.2020
- Author(s)
  Jin Endo
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K07423
[Presentation] プロレニン受容体による加齢性骨格筋萎縮の新規分子機構2020
- Author(s)
  遠藤　仁
- Organizer
  日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-18K07423
[Presentation] (Pro) renin receptor promotes development of sarcopenia via activation of Wnt-YAP signaling pathway2018
- Author(s)
  Jin Endo
- Organizer
  BCVR
- Data Source
  KAKENHI-PROJECT-18K07423
[Presentation] Omega-3 Fatty Acid Metabolism in Cardiac Macrophages2016
- Author(s)
  Jin Endo
- Organizer
  第80回日本循環器学会学術集会AHA-JCS Joint Symposium Functional Importance of Immune Cells in the Heart
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-26860586
[Presentation] Obesity accelerates T cell senescence in visceral adipose tissue.2015
- Author(s)
  Shirakawa K, Shinmura K, Endo J, Kataoka M, Yamamoto T, Katsumata Y, Anzai A, Isobe S, Yoshida N, Fukuda K ,Sano M.
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orange County Convention Center (Oralndo, FL, USA)
- Year and Date
  2015-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461116
[Presentation] Amelioration of adipose inflammation and insulin resistance in aged and diet-induced obese mice by targeting programmed death 1+ adipose T cells.2015
- Author(s)
  Shirakawa K, Yan X, Shinmura K, Endo J, Tamaki K, Katsumata Y, Yamamoto T, Anzai A, Matsuhashi T, Fukuda K, Sano M.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府、大阪市)
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-25461116
[Presentation] Cardiac macrophage-derived 18-HEPE, an EPA metabolite, prevents the progression of cardiac remodeling under pressure overload in mice.2015
- Author(s)
  Endo J
- Organizer
  PLM2015
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2015-02-15
- Data Source
  KAKENHI-PROJECT-26860586
[Presentation] Amelioration of adipose inflammation and insulin resistance in aged and diet-induced obese mice by targeting programmed death 1+ adipose T cells2015
- Author(s)
  Shirakawa K, Yan X, Shinmura K, Endo J, Tamaki K, Katsumata Y, Yamamoto T, Anzai A, Matsuhashi T, Fukuda K, Sano M.
- Organizer
  第79回日本循環器学会年次集会　YIA finalists講演
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-25461116
[Presentation] Amelioration of adipose inflammation and insulin resistance by targeting programmed death 1+ adipose T cells2014
- Author(s)
  白川公亮、佐野元昭、遠藤　仁、玉城香代子、伊藤健太郎、山本恒久、勝俣良紀、安西　淳、松橋智弘、福田恵一、森本耕吉、渡邉光博、八木田秀雄、新村　健。
- Organizer
  第14回日本坑加齢医学会総会
- Place of Presentation
  大阪
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-25461116
[Presentation] 18-HEPE, a bioactive products of n-3 Fatty Acid, prevents cardiac remodeling induced by pressure overload.2014
- Author(s)
  Endo J
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-26860586
[Presentation] 18-HEPE, an EPA metabolite released by macrophages, prevents against pressure overload-induced cardiac remodeling.2014
- Author(s)
  Endo J
- Organizer
  BCVS 2014
- Place of Presentation
  Las Vegas, Nevada, USA
- Year and Date
  2014-07-14
- Data Source
  KAKENHI-PROJECT-26860586
[Presentation] Programmed death 1+ T cells integrate adipose inflammation and develop insulin resistance in aged and type 2 diabetic mice.2014
- Author(s)
  Shirakawa K, Yan X, Sano M, Endo J, Ito K, Yamamoto T, Katsumata Y, Anzai A, Matsuhashi T, Fukuda K, Morimoto K, Watanabe M, Yagita H, Shinmura K.
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25461116

1. Shinmura Ken (70206332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. FUKUDA KEIICHI (20199227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. SANO MOTOAKI (30265798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 岩本卓士 (10348675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 勝俣良紀 (80464832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 有田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Endo Jin 遠藤 仁

ENDO JIN 遠藤 仁

遠藤 仁 エンドウ ジン

Research Projects

Research Products

Co-Researchers

Elucidation of the pathogenic mechanism of ATTRwt amyloidosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the cardioprotection mechanism mediated by mitochondrial regulatory proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of novel molecular mechanism of sarcopeniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An investigation of the imapacts of tissue fatty acid balance control in cardiovascular diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Amelioration of adipose inflammation and insulin resistance in aged and diet-induced obese mice by targeting programmed death-1+ adipose T cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨髄osteoblastic-zoneにおける多能性幹細胞の心筋分化の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医学のあゆみ「フェロトーシスにおけるミトコンドリア蛋白質 MITOLの新たな可能性」2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 代謝異常治療研究基金研究業績集 第41集20142015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] MRP1-Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia-Reperfusion2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic Targets for DOX-Induced Cardiomyopathy: Role of Apoptosis vs. Ferroptosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (Pro)renin receptor accelerates development of sarcopenia via activation of Wnt/YAP signaling axis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cardioprotective mechanism of omega-3 polyunsaturated fatty acids.2016

Author(s)

Journal Title

Data Source

[Journal Article] Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia/reperfusion.2016

Author(s)

Journal Title

DOI

Endo Jin 遠藤仁

ENDO JIN 遠藤仁

遠藤仁エンドウジン

[Book] 代謝異常治療研究基金研究業績集　第41集20142015