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Kawabori Masahito  川堀 真人

ORCIDConnect your ORCID iD *help
Researcher Number 50399870
Other IDs
Affiliation (Current) 2025: 北海道大学, 医学研究院, 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 北海道大学, 医学研究院, 講師
2019 – 2023: 北海道大学, 大学病院, 特任准教授
2021 – 2022: 北海道大学, 医学研究院, 助教
2017 – 2018: 北海道大学, 大学病院, 特任講師
2016: 北海道大学, 医学研究科, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related / Neurosurgery
Except Principal Investigator
Basic Section 56010:Neurosurgery-related
Keywords
Principal Investigator
間葉系幹細胞 / エクソソーム / 脳虚血 / 骨髄間葉系幹細胞 / 足場材 / 慢性期 / 腸 / 足場材合材 / 幹細胞 / 脳出血 … More / 脳・神経 / 虚血再灌流 / ラット / Sphingolipid / FTY720 / 脳血液関門 / 炎症 / 炎症反応 / フィンゴリモド / 脳梗塞 … More
Except Principal Investigator
脳虚血 / 間葉系幹細胞 / 脳梗塞 / エクソソーム / 幹細胞 / くも膜下出血 / 脊髄損傷 / 脳保護作用 / 抗酸化物質 / 虚血再灌流傷害 / 人工酸素運搬体 / もやもや病 / 幹細胞シート / シート / 一酸化炭素 / 細胞外小胞 / 骨髄間質細胞 / 認知機能 / 運動機能 / アルツハイマー病 / 脳挫傷 / Muse細胞 / 細胞治療 / 再生医療 / 脳保護 / 人工酸素運搬体HBOC / 遅発性脳血管攣縮 / 腸 / 腸ー脳相関 / ピロリ菌 / ピロリ菌感染 / RNF213 / 浅側頭動脈 / 遺伝子多型 / moyamoya病 / 遺伝子変異 Less
  • Research Projects

    (14 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (23 People)
  •  脳梗塞血栓回収治療後の間葉系幹細胞由来エクソソーム局所動注による神経保護効果

    • Principal Investigator
      栗栖 宏多
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  くも膜下出血後の神経炎症に対する間葉系幹細胞由来エクソソームの制御効果

    • Principal Investigator
      下田 祐介
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  間葉系幹細胞シートを用いたもやもや病の間接血行再建術における包括的研究

    • Principal Investigator
      藤村 幹
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  脳梗塞急性期に対する間葉系幹細胞由来細胞外小胞の経鼻的投与Principal Investigator

    • Principal Investigator
      川堀 真人
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  羊膜間葉系幹細胞由来エクソソームの脊髄損傷急性期における作用機序解明

    • Principal Investigator
      関 俊隆
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  Innovative Research of Neuroprotection for Delayed Cerebral Ischemia Associated with Cerebral Vasospasm after Subarachnoid Hemorrhage using Novel Hemoglobin-based Oxygen Carrier

    • Principal Investigator
      月花 正幸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  人工酸素運搬体を用いたmulti-targetの脳保護療法の開発

    • Principal Investigator
      鐙谷 武雄
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  広範性脳損傷に対する間葉系幹細胞培養液由来エクソソームの経鼻的投与の検討

    • Principal Investigator
      穂刈 正昭
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  Comprehensive Bench-to-Bedside Research on Regenerative Medicine for Ischemic stroke with Bone Marrow Stromal Cell-derived Extracellular Vesicles (EVs)

    • Principal Investigator
      KURODA Satoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      University of Toyama
  •  Spine-gut relationship in the treatment of spinal cord injury with stem cell

    • Principal Investigator
      Seki Toshitaka
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  Stem cell combined with scaffold for treating chronic cerebral hemorrhagePrincipal Investigator

    • Principal Investigator
      Kawabori Masahito
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  Development of neruoprotectice therapy by artificial oxygen carriier with antioxidant function

    • Principal Investigator
      Abumiya Takeo
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  Relationship between Chronic inflammation and progression of Moyamoya disease

    • Principal Investigator
      Hokari Masaaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  Protective role of sphingo-lipid against brain ischemic re-perfusion injuryPrincipal Investigator

    • Principal Investigator
      Kawabori Masahito
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurosurgery
    • Research Institution
      Hokkaido University

All 2024 2022 2019 2018

All Journal Article Presentation

  • [Journal Article] Intracerebral transplantation of MRI-trackable autologous bone marrow stromal cells for patients with subacute ischemic stroke2024

    • Author(s)
      Kawabori Masahito、Kuroda Satoshi、Shichinohe Hideo、Kahata Kaoru、Shiratori Souichi、Ikeda Satoshi、Harada Taisuke、Hirata Kenji、Tha Khin Khin、Aragaki Masato、Terasaka Shunsuke、Ito Yoichi M.、Nishimoto Naoki、Ohnishi Shunsuke、Yabe Ichiro、Kudo Kohsuke、Houkin Kiyohiro、Fujimura Miki
    • Journal Title

      Med

      Volume: - Issue: 5 Pages: 432-444.e4

    • DOI

      10.1016/j.medj.2024.02.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K11362, KAKENHI-PROJECT-21H02857, KAKENHI-PROJECT-21H03043
  • [Journal Article] Intravenous Administration of Mesenchymal Stem Cell-Derived Exosome Alleviates Spinal Cord Injury by Regulating Neutrophil Extracellular Trap Formation through Exosomal miR-125a-3p2024

    • Author(s)
      Morishima Yutaka、Kawabori Masahito、Yamazaki Kazuyoshi、Takamiya Soichiro、Yamaguchi Sho、Nakahara Yo、Senjo Hajime、Hashimoto Daigo、Masuda Sakiko、Fujioka Yoichiro、Ohba Yusuke、Mizuno Yuki、Kuge Yuji、Fujimura Miki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 4 Pages: 2406-2406

    • DOI

      10.3390/ijms25042406

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08557, KAKENHI-PROJECT-22KF0004, KAKENHI-PLANNED-20H05872
  • [Journal Article] Intravenous transplantation of amnion-derived mesenchymal stem cells promotes functional recovery and alleviates intestinal dysfunction after spinal cord injury.2022

    • Author(s)
      Takamiya S, Kawabori M, Yamazaki K, Yamaguchi S, Tanimori A, Yamamoto K, Ohnishi S, Seki T, Konno K, Tha KK, Hashimoto D, Watanabe M, Houkin K, Fujimura M.
    • Journal Title

      PLoS One

      Volume: 17 Issue: 7 Pages: e0270606-e0270606

    • DOI

      10.1371/journal.pone.0270606

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06746, KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-20K09361
  • [Journal Article] FTY720 (fingolimod) ameliorates brain injury through multiple mechanisms and is a strong candidate for stroke treatment2019

    • Author(s)
      Zifeng Wang, Masahito Kawabori, Kiyohiro Houkin
    • Journal Title

      Current Medicinal Chemistry

      Volume: 印刷中

    • NAID

      120006869886

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19992
  • [Journal Article] 中国における中枢神経疾患に対する細胞治療の最新動向2018

    • Author(s)
      王シホウ, 譚成博, 川堀真人, 七戸秀夫, 寶金清博.
    • Journal Title

      北海道医学雑誌

      Volume: Epub ahead of print

    • NAID

      120006482592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19992
  • [Presentation] FTY720 (fingolimod) ameliorates brain injury through multiple mechanisms and is a strong candidate for stroke treatment2019

    • Author(s)
      Zifeng Wang, Masahito Kawabori, Kiyohiro Houkin
    • Organizer
      International Stroke Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19992
  • 1.  伊東 雅基 (10399850)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  藤村 幹 (00361098)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  Abumiya Takeo (80270726)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  小松 晃之 (30298187)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  Hokari Masaaki (30622807)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Seki Toshitaka (80241446)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  数又 研 (60634144)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  寳金 清博 (90229146)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KURODA Satoshi (10301904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  中山 若樹 (40421961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  長内 俊也 (90622788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  杉山 拓 (70748863)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  大西 俊介 (10443475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  七戸 秀夫 (80374479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  月花 正幸 (40812285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  柏崎 大奈 (50374484)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  堀 恵美子 (90372482)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  栗栖 宏多 (30869839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  下田 祐介 (60792827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  久下 裕司 (70321958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  Wang Zifeng
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 22.  IKEDA Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  今野 幸太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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