Yamashita Toshiharu 山下年晴

… Alternative Names

YAMASHITA Toshiharu 山下年晴

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Researcher Number	50400677
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 助教
Affiliation (based on the past Project Information) *help	2012 – 2024: 筑波大学, 医学医療系, 助教 2007 – 2010: 筑波大学, 大学院・人間総合科学研究科, 助教
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Tumor biology Except Principal Investigator Cerebral neurosurgery / Basic Section 49010:Pathological biochemistry-related / Basic Section 49030:Experimental pathology-related / Basic Section 56010:Neurosurgery-related / Pathological medical chemistry / Neurosurgery / Regenerative medicine / Circulatory organs internal medicine
Keywords	Principal Investigator 低酸素応答 / 血管新生 / がん転移 / がん / 分子腫瘍学 / 低酸素 / がん微小環境 / 血管内皮細胞 / 低酸素応答転写因子 Except Principal Investigator 間葉系幹細胞 … More / 血管新生抑制 / 再生医学 / グリオーマ / 血管新生 / 細胞外小胞 / 2型糖尿病 / chetomin / 血管新生抑制療法 / 糖尿病 / 管腔形成 / 神経血管ワイアリング / VEGF / 神経膠腫 / 創傷治癒 / 移植・再生医療 / SDF1 / 脳神経疾患 / 低酸素 / 血管内皮前駆細胞 / 肥満 / 若返り / ２型糖尿病 / 細胞小胞 / 老化 / antiangiogenic therapy / angiogenesis / vasculogenic mimicry / anti-angiogenesis / glioblastoma / 血管新生抑制療 / 低酸素領域 / bevacizumab / bavacizumab / vascular co-option / vascular mimicry / 膠芽腫 / 血管mimicry / 血管co-option / VEDGF抵抗性 / 機能性幹細胞 / マイクロベシクル / western解析 / RT-PCR解析 / 免疫組織化学 / Slit2 / in vivo imaging / 脳腫瘍増殖制御 / siRNA / 血管内皮細胞 / 神経血管ワイヤリング / slit2 / 低酸素誘導因子 / lenalidomide / テーラーメイド細胞治療 / 脂肪由来間葉系幹細胞 / サブタイプ / 幹細胞 / 遺伝子発現 / 膠芽種 / 悪性脳腫瘍 / 微小血管内皮細胞 / IDH1 / 腫瘍幹細胞 / ペプチド療法 / 脳腫瘍 / 予後因子 / 血管密度 / 内皮細胞 / RANTES / 周皮細胞 / 微小環境 / 一過性脳梗塞モデル / 機能的血管内皮前駆細胞 / 動物モデル / 脳血管障害 / 脳梗塞 / 再生医療 / 虚血 / 細胞・組織 / 循環器・高血圧 / 血管内皮増殖因子 / 遺伝子 / CXCR7 / CXCR4 / SDF-1 / 腫瘍血管内皮細胞 / ケモカイン / 脳腫瘍学 Less

間葉系幹細胞由来細胞外小胞を用いたエピジェネティック制御機構の解明
- Principal Investigator
  
  大根田修
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  University of Tsukuba
Development of MSC-derived extracellular vesicle for clinical application
- Principal Investigator
  
  Ohneda Osamu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  University of Tsukuba
Molecular mechanisms and target therapy of vessel co-option and mimicry for glioblastoma
- Principal Investigator
  
  Takano Shingo
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Functional analysis of mesenchymal stem cells derived from type 2 diabetes
- Principal Investigator
  
  OHNEDA OSAMU
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
Developmental mechanisms of glioblastoma-derived blood vessels and their effect on malignancyPrincipal Investigator
- Principal Investigator
  
  Yamashita Toshiharu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  University of Tsukuba
Anti-angiogenic therapy for brain tumors targeting neuro-vascular wiring molecules
- Principal Investigator
  
  TAKANO SHINGO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Tsukuba
Anti-angiogenic therapy for glioma beyond VEGF inhibition based on tumor microenvironment
- Principal Investigator
  
  TAKANO Shingo
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tsukuba
Characterization of human adipose tissue-derived mesenchymal stem cells
- Principal Investigator
  
  OHNEDA OSAMU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  University of Tsukuba
Analysis of the effects of hypoxia inducible factor for tumor metastasisPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Toshiharu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
New degenerative therapy for cerebral infarction by the functional vascular endothelial progenitor cells
- Principal Investigator
  
  SUZUKI Kensuke
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Dokkyo Medical University
A functional analysis of HIF for tumor metastasisPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Toshiharu
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
Analysis of functional EPC for the treatment of ischemic disease
- Principal Investigator
  
  OHNEDA Osamu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
Antiangiogenic therapy using endothelial progenitor cells for malignant tumors
- Principal Investigator
  
  TAKANO Shingo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tsukuba

All 2022 2021 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues.2022
- Author(s)
  Ngo NH, Chang YH, Vuong CK, Yamashita T, Obata-Yasuoka M, Hamada H, Osaka M, Hiramatsu Y, Ohneda O.
- Journal Title
  
  Frontier Cell Developmental Biology
  
  Volume: 10 Pages: 1-15
- DOI
  10.3389/fcell.2022.869850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06964
[Journal Article] Type 2 Diabetes Mellitus Promotes the Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells into Cancer-Associated Fibroblasts, Induced by Breast Cancer Cells.2022
- Author(s)
  Chang YH, Ngo NH, Vuong CK, Yamashita T, Osaka M, Hiramatsu Y, Ohneda O.
- Journal Title
  
  Stem Cells and Development
  
  Volume: 31 Issue: 21-22 Pages: 659-671
- DOI
  10.1089/scd.2022.0086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06964
[Journal Article] Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions2021
- Author(s)
  Khanh Vuong Cat、Fukushige Mizuho、Chang Yun Hsuan、Hoang Ngo Nhat、Yamashita Toshiharu、Obata-Yasuoka Mana、Hamada Hiromi、Osaka Motoo、Hiramatsu Yuji、Ohneda Osamu
- Journal Title
  
  Stem Cells and Development
  
  Volume: 30 Issue: 15 Pages: 758-772
- DOI
  10.1089/scd.2021.0065
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09237, KAKENHI-PROJECT-21K06964
[Journal Article] Elevated Expression of Dkk-1 by Glucocorticoid Treatment Impairs Bone Regenerative Capacity of Adipose Tissue-Derived Mesenchymal Stem Cells2018
- Author(s)
  Kato Toshiki、Khanh Vuong Cat、Sato Kazutoshi、Kimura Kenichi、Yamashita Toshiharu、Sugaya Hisashi、Yoshioka Tomokazu、Mishima Hajime、Ohneda Osamu
- Journal Title
  
  Stem Cells and Development
  
  Volume: 27 Issue: 2 Pages: 85-99
- DOI
  10.1089/scd.2017.0199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06823
[Journal Article] Glucocorticoid impaired the wound healing ability of endothelial progenitor cells by reducing the expression of CXCR4 in the PEG2 pathway.2018
- Author(s)
  Carolina E, Kato T, Khanh VC, Moriguchi K, Yamashita T, Takeuchi K, Hamada H, Ohneda O.
- Journal Title
  
  Front Med
  
  Volume: 5 Pages: 1-17
- DOI
  10.3389/fmed.2018.00276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08609
[Journal Article] Hypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cells.2017
- Author(s)
  Shiraishi A, Tachi K, Essid N, Tsuboi I, Nagano M, Kato T, Yamashita T, Bando H, Hara H, Ohneda O.
- Journal Title
  
  Cancer Science
  
  Volume: 108(3) Issue: 3 Pages: 362-372
- DOI
  10.1111/cas.13147
- NAID
  120007129221
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06823
[Journal Article] SDF-1 improves wound healing ability of glucocorticoid-treated adipose tissue-derived mesenchymal stem cells2017
- Author(s)
  Kato Toshiki、Khanh Vuong Cat、Sato Kazutoshi、Takeuchi Kosuke、Carolina Erica、Yamashita Toshiharu、Sugaya Hisashi、Yoshioka Tomokazu、Mishima Hajime、Ohneda Osamu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 493 Issue: 2 Pages: 1010-1017
- DOI
  10.1016/j.bbrc.2017.09.100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06823
[Journal Article] Increased expression of EGR-1 in diabetic human adipose tissue-derived mesenchymal stem cells reduces their wound healing capacity.2016
- Author(s)
  Nhu-Thuy Trinh, Toshiharu Yamashita, Kinuko Ohneda, Kenichi Kimura, Georgina To'a Salazar, Fujio Sato, Osamu Ohneda
- Journal Title
  
  Stem Cells and Development
  
  Volume: 25 Pages: 760-773
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08609
[Journal Article] FOXA1 expression affects to the proliferation activity of luminal breast cancer stem cell populations.2016
- Author(s)
  Tachi K, Shiraishi A, Bando H, Yamashita T, Tsuboi I, Kato T, Hara H, Ohneda O.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Issue: 3 Pages: 281-289
- DOI
  10.1111/cas.12870
- NAID
  120007135537
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06823, KAKENHI-PROJECT-25461972
[Journal Article] Dual Functions of Hypoxia - InducibleFactorlAlphaforthe Commitment of Mouse Embryonic Stem Cells Toward a Neural Lineage2014
- Author(s)
  Zhao Y,Matsuo, Takasaki M,Tsuboi I,Kimura K,Salazar G.T.,Yamashita T,Ohneda O
- Journal Title
  
  Stem Cells Dev
  
  Volume: 7 Issue: 3 Pages: 219-229
- DOI
  10.1089/scd.2013.0328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790308
[Journal Article] Deficiency of NOX1/nicotinamide adenine dinucleotide phosphate, reduced form oxidase leads to pulmonary vascular remodeling.2014
- Author(s)
  Iwata K, Ikami K, Matsuno K, Yamashita T, Shiba D, Ibi M, Matsumoto M, Katsuyama M, Cui W, Zhang J, Zhu K, Takei N, Kokai Y, Ohneda O, Yokoyama T, Yabe-Nishimura C.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 34(1) Issue: 1 Pages: 110-119
- DOI
  10.1161/atvbaha.113.302107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790198, KAKENHI-PROJECT-24790308, KAKENHI-PROJECT-26870464, KAKENHI-PROJECT-24500445, KAKENHI-PUBLICLY-25116521
[Journal Article] The role of CCL5 in the ability of adipose tissue-derived mesenchymal stem cells to support repair of ischemic regions.2014
- Author(s)
  Kimura K, Nagano M, Salazar G, Yamashita T, Tsuboi I, Mishima H, Matsushita S, Sato F, Yamagata K, Ohneda O.
- Journal Title
  
  Stem Cells Dev.
  
  Volume: 23(5) Issue: 5 Pages: 488-501
- DOI
  10.1089/scd.2013.0307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592980, KAKENHI-PROJECT-24615002, KAKENHI-PROJECT-24790308, KAKENHI-PROJECT-24790735
[Journal Article] Dual Functions of Hypoxia-Inducible Factor 1 Alpha for the Commitment of Mouse Embryonic Stem Cells Toward a Neural Lineage2014
- Author(s)
  Zhao Y, Matsuo-Takasaki M, Tsuboi I, Kimura K, Salazar GT, Yamashita T, Ohneda O.
- Journal Title
  
  Stem Cells and Development
  
  Volume: 印刷中 Issue: 18 Pages: 2143-2155
- DOI
  10.1089/scd.2013.0278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23618004, KAKENHI-PROJECT-24790308
[Journal Article] Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation2013
- Author(s)
  Akimoto K, Kimura K, Nagano M, Takano S, To'a Salazar G, Yamashita T, Ohneda O.
- Journal Title
  
  Stem Cells Dev
  
  Volume: 22 Issue: 9 Pages: 1370-1386
- DOI
  10.1089/scd.2012.0486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390339, KAKENHI-PROJECT-24615002, KAKENHI-PROJECT-24659645, KAKENHI-PROJECT-24790308, KAKENHI-PROJECT-24790735
[Journal Article] Functional endothelial progenitor cells selectively recruit neurovascular protective monocyte-derived F4/80(+) /Ly6c(+) macrophages in a mouse model of retinal degeneration2013
- Author(s)
  Fukuda S, Nagano M, Yamashita T, Kimura K, Tsuboi I, Salazar G, Ueno S, Kondo M, Kunath T, Oshika T, Ohneda O
- Journal Title
  
  Stem Cells
  
  Volume: 31 Issue: 10 Pages: 2149-2161
- DOI
  10.1002/stem.1469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592603, KAKENHI-PROJECT-24790308, KAKENHI-PROJECT-24790735, KAKENHI-PROJECT-25861614
[Journal Article] A subpopulation of endothelial progenitor cells with low aldehyde dehydrogenase activity attenuates acute ischemic brain injury in rats.2012
- Author(s)
  Kazuhiro Nakamura, Hideo Tsurushima, Aiki Marushima, Masumi Nagano, Toshiharu Yamashita, Kensuke Suzuki, Osamu Ohneda, Akira Matsumura.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 418 Issue: 1 Pages: 87-92
- DOI
  10.1016/j.bbrc.2011.12.139
- NAID
  120007130720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24615002, KAKENHI-PROJECT-24790308, KAKENHI-PROJECT-24790735
[Journal Article] A subpopulation of endothelial progenitor cells with low aldehyde dehydrogenase activity attenuates acute ischemic brain injury in rats2012
- Author(s)
  Nakamura K, Tsurushima H, Marushima A, Nagano M, Yamashita T, Suzuki K, Ohneda O, Matsumura A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418(1) Pages: 87-92
- NAID
  120007130720
- URL
  http://dx.doi.org/10.1016/j.bbrc.2011.12.139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591833
[Journal Article] Identification of human placenta-derived mesenchymal stem cells involved in re-endothelialization.2011
- Author(s)
  Tu TC, Kimura K, Nagano M, Yamashita T, Ohneda K, Sugimori H, Sato F, Sakakibara Y, Hamada H, Yoshikawa H, Son HN, Ohneda O.
- Journal Title
  
  J Cell Physiol. 226(1)
  
  Pages: 224-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790304
[Journal Article] Identification of human placenta derived mesenchymal stem cells involved in re-endothelialization.2011
- Author(s)
  Tu TC, Kimura K, Nagano M, Yamashita T, Ohneda K, Sugimori H, Sato F, Sakakibara Y, Hamada H, Yoshikawa H, Son HN, Ohneda O
- Journal Title
  
  J Cell Physiol.
  
  Volume: Jan 226(1) Pages: 224-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790304
[Journal Article] Molecular therapeutic targets for glioma angiogenesis.2010
- Author(s)
  Takano S, Yamashita T, Ohneda O.
- Journal Title
  
  J Oncol. 35
  
  Pages: 1908-1918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790304
[Journal Article] Molecular therapeutic targets for glioma angiogenesis.2010
- Author(s)
  Takano S, Yamashita T, Ohneda O
- Journal Title
  
  J Oncol.
  
  Volume: 35 Pages: 1908-1918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790304
[Journal Article] Molecular therapeutic targets for glioma angiogenesis2010
- Author(s)
  Takano S, Yamashita T, Ohneda O
- Journal Title
  
  J Oncol. 2010
  
  Pages: 351908-351908
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] Hypoxia responsive mesenchymal stem cells derived from human umbilical cord blood are effective for bone repair2010
- Author(s)
  Nagano M, Kimura K, Yamashita T, Ohneda K, Nozawa D, Hamada H, Yoshikawa H, Ochiai N, Ohneda O.
- Journal Title
  
  Stem Cells Dev. Mar26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790304
[Journal Article] Hypoxia responsive mesenchymal stem cells derived from human umbilical cord blood are effective for bone repair.2010
- Author(s)
  Nagano M, Kimura K, Yamashita T, Ohneda K, Nozawa D, Hamada H, Yoshikawa H, Ochiai N, Ohneda O
- Journal Title
  
  Stem Cells Dev.
  
  Volume: Aug 19(8) Pages: 1195-1210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790304
[Journal Article] Hypoxia responsive mesenchymal stem cells derived from human umbilical cord blood are effective for bone repair.2010
- Author(s)
  Nagano M, Kimura K, Yamashita T, Ohneda K, Nozawa D, Hamada H, Yoshikawa H, Ochiai N, Ohneda O.
- Journal Title
  
  Stem Cells Dev. Mar 26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] Hypoxia responsive mesenchymal stem cells derived from human umbilical cord blood are effective for bone repair.2010
- Author(s)
  Nagano M, Kimura K, Yamashita T, Ohneda K, Nozawa D, Hamada H, Yoshikawa H, Ochiai N, Ohneda O.
- Journal Title
  
  Stem Cells Dev. 19(8)
  
  Pages: 1195-1210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790304
[Journal Article] Identification of human placenta-derived mesenchymal stem cells involved in re-endothelialization2010
- Author(s)
  Tu T, Kimura K, Nagano M, Yamashita T, Ohneda K, Sugimori H, Sato F, Sakakibara Y, Hamada H, Yoshikawa H, Son H, Ohneda O
- Journal Title
  
  J Cell Physiol. 226
  
  Pages: 224-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] Hypoxia responsive mesenchymal stem cells derived from human umbilical cord blood are effective for bone repair2010
- Author(s)
  Nagano M, Kimura K, Yamashita T, Ohneda K, Nozawa D, Hamada H, Yoshikawa H, Ochiai N, Ohneda O
- Journal Title
  
  Stem cells and Dev. 19
  
  Pages: 1195-1210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] The role of chemokine SDF-1 and CXCR4 in glioma angiogenesis and invasiveness : interaction between glioma and glioma-derived endothelial cells2009
- Author(s)
  Takano S, Osuka S, Mashiko R, Ohneda O, Nagano M, Yamashita T, Matsumura A
- Journal Title
  
  Neuro Oncol 11
  
  Pages: 219-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591576
[Journal Article] グリオーマ血管内皮細胞から考えたグリオーマの治療2009
- Author(s)
  高野晋吾、益子良太、大須賀覚、山本哲哉、中井啓、鶴淵隆夫、長野真澄、山下年晴、大根田修、松村明
- Journal Title
  
  ニューロオンコロジー (in press)
- Data Source
  KAKENHI-PROJECT-18591576
[Journal Article] The microenvironment for erythropoiesis is regulated by HIF-2alpha through VCAM-1 in endothelial cells.2008
- Author(s)
  Yamashita T, Ohneda 0, Sakiyama A, 他3名
- Journal Title
  
  Blood 112
  
  Pages: 1482-1492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] The microenvironment for erythropoiesis is regulated by HIF-2alpha through VCAM-1 in endothelial cells2008
- Author(s)
  Yamashita T, Ohneda O, Sakiyama A, Iwata F, Ohneda K, Fujii-Kuriyama Y
- Journal Title
  
  Blood 112
  
  Pages: 1482-1492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] Hypoxia-inducible transcription factor-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1.2008
- Author(s)
  Yamashita T, Ohneda K, Nagano M, Ohneda 0, ft. 51
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 18926-18936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] HIF-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin Al2008
- Author(s)
  Yamashita T, Ohneda K. Nagano M, Miyoshi C, Kaneko N, Miwa Y, Yamamoto M, Ohneda O, Fujii-Kuriyama Y
- Journal Title
  
  J Biol Chem 283
  
  Pages: 18926-18936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Journal Article] Abnormal heart development and lung remodeling in mice lacking a HIF-related bHLH-PAS protein NEPAS2008
- Author(s)
  Yamashita T, Ohneda O, Nagano M, Iemitsu M, Makino Y, Tanaka H, Miyauchi H, Goto K, Ohneda K, Fujii-Kuriyama Y, Lorenz Poellinger, Yamamoto M
- Journal Title
  
  Mol.Cell.Biol. 28
  
  Pages: 1285-1297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] HIF-2α 発現低下によって惹起されるHIF-1α 代償作用の解析2016
- Author(s)
  山下年晴，坪井一輝，平松大宗，加藤俊貴，大根田修
- Organizer
  第89回日本生化学大会
- Place of Presentation
  宮城県仙台市仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K06823
[Presentation] HIF-2α 発現低下によって惹起されるHIF-1α 代償作用の解析2016
- Author(s)
  山下年晴，坪井一輝，平松大宗，加藤俊貴，大根田修
- Organizer
  第14回がんとハイポキシア研究会
- Place of Presentation
  岐阜県岐阜市岐阜グランドホテル
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K06823
[Presentation] ステロイド薬投与による脂肪組織由来間葉系幹細胞への影響2013
- Author(s)
  加藤俊貴,木村健一,長野真澄,山下年晴,秋本恵子,三島初,大根田修
- Organizer
  第l2回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] Deficient expression of HIF-2α in spleen results in compensatory angiogenesis by up-regulation of HIF-1 α2013
- Author(s)
  Ikki Tsuboi, Toshiharu Yamashita, Satomi Kobayashi, Osamu Ohneda
- Organizer
  第36回　日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] Deficient expression of HIF - 2a in spleen results in compensatory angiogenesis by up - regulated of HIF - la2013
- Author(s)
  Ikki Tsuboi,Toshiharu Yamashita,Satomi Kobayashi,Osamu Ohneda
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] ヒト間葉系幹細胞のグリオブラストーマ増殖抑制に対する作用機構解明.2013
- Author(s)
  秋本恵子,木村健一, 長野真澄, 山下年晴, 高野晋吾, 大根田修.
- Organizer
  第12回　日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] ステロイド薬投与による脂肪組織由来間葉系幹細胞への影響2013
- Author(s)
  加藤俊貴，木村健一，長野真澄，山下年晴，秋本恵子，三島初，大根田修．
- Organizer
  第12回　日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] ヒト間葉系幹細胞のグリオブラストーマ増殖抑制に対する作用機構解明2013
- Author(s)
  秋本恵子,木村健一,長野真澄,山下年晴,高野晋吾,大根田修
- Organizer
  第l2回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] 異なる歯組織形成段階における歯髄幹細胞の比較検討2013
- Author(s)
  菊地豪,山系憲司,佐藤和聡,木村健一,山下年晴,大根田修
- Organizer
  第l2回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] 異なる歯組織形成段階における歯髄幹細胞の比較解析2013
- Author(s)
  菊地豪，山縣憲司，佐藤和聡，木村健一，山下年晴，大根田修．
- Organizer
  第12回　日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] HIF-1a expression in ALDH-positive breast cancer is involved in cancer progression.2012
- Author(s)
  白石章，木村健一，長野真澄，山下年晴，坂東裕子，原尚人，大根田修.
- Organizer
  第10回　がんとハイポキシア研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] 肺由来血管内皮細胞における低酸素応答転写因子HIF - 3aの機能解析2012
- Author(s)
  小林里美,山下年晴,長野真澄,木村健一,大根田修
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] HIF-2akd/nullヘテロマウスを用いた造血機能解析2012
- Author(s)
  坪井一輝，山下年晴，木村健一，大根田修．
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] Deficient expression of HIF - 2a in endothelial cell cause upregulation of HIF - la and compensatory angiogenesis2012
- Author(s)
  坪井一輝,山下年晴,木村健一,小林里美,長野真澄,大根田修
- Organizer
  第l0回がんとハイポキシア研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] Deficient expression of HIF-2a in endothelial cell cause upregulation of HIF-1a and compensatory angiogenesis.2012
- Author(s)
  坪井一輝，山下年晴，木村健一，小林里美，長野真澄，大根田修．
- Organizer
  第10回　がんとハイポキシア研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] HIF - 2a kd/nullヘテロマウスを用いた造血機能解析2012
- Author(s)
  坪井一輝,山下年晴,木村健一,大根田修
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] 肺由来血管内皮細胞における低酸素応答転写因子HIF-3aの機能解析2012
- Author(s)
  小林里美，山下年晴，長野真澄，木村健一，大根田修．
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] HIF - la expression in ALDH - positive breast cancer is involved in cancer pogression2012
- Author(s)
  白石章,木村健一,長野真澄,山下年晴,板東裕子,原尚人,大根田修
- Organizer
  第l0回がんとハイポキシア研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] Hypoxia inducible factor - 3a regulates its target genes in association with HIF - la and HIF - 2a2012
- Author(s)
  小林里美,山下年晴,長野真澄,木村健一,坪井一輝,大根田修
- Organizer
  第l0回がんとハイポキシア研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] Hypoxia inducible factor-3a regulates its target genes in association with HIF-1a and HIF-2a.2012
- Author(s)
  小林里美，山下年晴，長野真澄，木村健一，坪井一輝，大根田修．
- Organizer
  第10回　がんとハイポキシア研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790308
[Presentation] Glioblastoma抑制に関するヒト間葉系幹細胞の影響についての機能解析2011
- Author(s)
  秋本恵子、木村健一、長野真澄、高野晋吾、山下年晴、大根田修
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 原発性乳がん細胞を用いた低酸素応答性における機能解析2011
- Author(s)
  白石章, 木村健一, 長野真澄, 山下年晴, 坂東裕子, 原尚人, 大根田修
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 低酸素応答性の高い間葉系幹細胞を用いた骨治療2011
- Author(s)
  木村健一, 長野真澄, 山下年晴, 野澤大輔, 濱田洋美, 落合直之, 吉川裕之, 大根田修
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] HIF-2α knockdown miceを用いたマウス成体造血機構における機能解析2011
- Author(s)
  坪井一輝、山下年晴、木村健一、大根田修
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 血管内皮細胞におけるHIF因子とがん転移との関連性の解析2011
- Author(s)
  山下年晴, 小林里美, 坪井一輝, 長野真澄, 大根田修
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 機能性が高い血管内皮前駆細胞の網膜色素変性症モデルマウスへの投与効果の検討2011
- Author(s)
  福田慎一, 長野真澄, 山下年晴, 大鹿哲郎, 大根田修
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] マウス肺の内皮細胞におけるHypoxia Inducible Factor-3αの機能解析2011
- Author(s)
  小林里美, 山下年晴, 長野真澄, 木村健一, 大根田修
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] CXCR7特異抑制物質による膠芽腫血管新生および増殖の抑制2010
- Author(s)
  高野晋吾, 益子良太, 山下年晴, 大根田修, 大須賀覚, 松村明
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 腫瘍血管内皮細胞におけるHIF機能解析2010
- Author(s)
  山下年晴, 小林里美, 坪井一輝, 長野真澄, 大根田修
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 低酸素応答性における乳がん細胞の機能解析2010
- Author(s)
  白石章, 木村健一, 長野真澄, 山下年晴, 板東裕子, 原尚人, 大根田修
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] ヒト血管内皮細胞の虚血改善能におけるHIF-2αとCXCR4の機能解析2010
- Author(s)
  長野真澄,山下年晴,濱田洋美,大根田絹子,木村健一,吉川裕之,大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] 低酸素条件下におけるES細胞の神経分化2010
- Author(s)
  趙陽, 高崎(松尾)真美, 長野真澄, 山下年晴, 木村健一, 坪井一輝, 大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] ヒト血管内皮細胞の虚血改善能におけるHIF-2αとCXCR4の機能解析2010
- Author(s)
  長野真澄, 山下年晴, 濱田洋美, 大根田絹子, 木村健一, 吉川裕之, 大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 腫瘍血管内皮細胞におけるHIF機能の解析.2010
- Author(s)
  山下年晴, 大根田修, 他3名
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] 腫瘍血管内皮細胞におけるHIF機能の解析2010
- Author(s)
  山下年晴,小林里美,坪井一輝,長野真澄,大根田修
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] CXCR7特異抑制物質による膠芽腫血管新生および増殖の抑制2010
- Author(s)
  高野晋吾, 益子良太, 山下年晴, 大根田修, 大須賀覚, 松村明
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] マウス肺の血管内皮細胞におけるHIF-3alphaの機能解析2010
- Author(s)
  小林里美, 山下年晴, 長野真澄, 木村健一, 大根田修
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] CD349 is an useful marker to isolate placenta-derived mesenchymal stem cells in accordance with functional property2010
- Author(s)
  木村健一,長野真澄,山下年晴,大根田修
- Organizer
  20th World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] 脂肪組織由来間葉系幹細胞と骨髄由来間葉系幹細胞の in vivo 機能解析2010
- Author(s)
  木村健一, 長野真澄, 山下年晴, 秋本恵子, 野澤大輔, 杉森治彦, 落合直之, 榊原譲, 大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 脂肪組織由来間葉系幹細胞と骨髄由来間葉系幹細胞のin vivo機能解析2010
- Author(s)
  木村健一, 長野真澄, 山下年晴, 秋本恵子, 野澤大輔, 杉森治彦, 落合直之, 榊原譲, 大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] グリオブラストーマ抑制に関するヒト間葉系幹細胞の影響についての機能解析2010
- Author(s)
  秋本恵子, 木村健一, 長野真澄, 高野晋吾, 山下年晴, 大根田修
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] ヒト血管内皮細胞の虚血改善能におけるHIF-2αとCXCR4の機能解析2010
- Author(s)
  長野真澄, 山下年晴, 濱田洋美, 大根田絹子, 木村健一, 吉川裕之, 大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 脂肪組織由来間葉系幹細胞と骨髄由来間葉系幹細胞のin vivo機能解析2010
- Author(s)
  木村健一,長野真澄,山下年晴,秋本恵子,野澤大輔,杉森治彦,落合直之,榊原譲,大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] CXCR4 is crucial for ischemic tissue repair through HIF-2α in endothelial progenitor cells2010
- Author(s)
  長野真澄,木村健一,山下年晴,大根田修
- Organizer
  20th World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] マウス造血微小環境におけるHIF-2alphaの機能解析2010
- Author(s)
  坪井一輝, 山下年晴, 木村健一, 大根田修
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] ヒト血管内皮細胞の虚血改善能におけるHIF-2αとCXCR4の機能解析2010
- Author(s)
  長野真澄, 山下年晴, 濱田洋美, 大根田絹子, 木村健一, 吉川裕之, 大根田修
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] 低酸素応答性における乳がん細胞の機能解析2010
- Author(s)
  白石章, 木村健一, 長野真澄, 山下年晴, 板東裕子, 原尚人, 大根田修
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 治療効果の高い間葉系幹細胞の単離およびその機能解析2009
- Author(s)
  木村健一,長野真澄,山下年晴,野澤大輔,濱田洋実,落合直之,吉川裕之,大根田修
- Organizer
  日本生化学会関東支部例会
- Place of Presentation
  つくば
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] がん転移形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴, 長野真澄, 坪井一輝, 大根田修
- Organizer
  第32回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] がん転移巣形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴, 長野真澄, 坪井一輝, 大根田修
- Organizer
  第七回がんとハイポキシア研究会
- Place of Presentation
  京都
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] がん転移巣形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴, 長野真澄, 坪井一輝, 大根田修
- Organizer
  第七回がんとハイポキシア研究会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] SDF-1とCXCR7はグリオーマの血管新生の重要な標的分子である2009
- Author(s)
  高野晋吾, 山下年晴, 長野真澄, 大須賀覚, 益子良太, 大根田修
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療と機能解析2009
- Author(s)
  秋本恵子,木村健一,長野真澄,高野晋吾,山下年晴,大根田修
- Organizer
  日本生化学会関東支部例会
- Place of Presentation
  つくば
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] 治療効果の高い間葉系幹細胞の単離およびその機能解析2009
- Author(s)
  木村健一, 長野真澄, 山下年晴, 野澤大輔, 濱田洋実, 落合直之, 吉川裕之, 大根田修
- Organizer
  平成21年度日本生化学会関東支部例会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] SDF-1とCXCR7はグリオーマの血管新生の重要な標的分子である2009
- Author(s)
  高野晋吾, 山下年晴, 長野真澄, 大須賀覚, 益子良太, 大根田修
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 治療効果の高い間葉系幹細胞の単離およびその機能解析2009
- Author(s)
  木村健一,長野真澄,山下年晴,野澤大輔,濱田洋実,落合直之,吉川裕之,大根田修
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] Hypoxia inducible factor-3αの機能解析2009
- Author(s)
  小林里美,山下年晴,植田崇史,中井秀人,長野真澄,大根田修
- Organizer
  第七回がんとハイポキシア研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] SDF-1とCXCR7はグリオーマの血管新生の重要な標的分子である2009
- Author(s)
  高野晋吾, 山下年晴, 長野真澄, 大須賀覚, 益子良太, 大根田修
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] Mesenchymal stem cells is useful for cell therapy of glioblastoma multiforme2009
- Author(s)
  秋本恵子,木村健一,長野真澄,高野晋吾,山下年晴,大根田修
- Organizer
  第32回分子生物学学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] Differential Potential of Endothelial Progenitor Cells to Promote Arteriogenesis and Angiogenesis2009
- Author(s)
  Haruhiko Sugimori, Masumi Nagano, Toshiharu Yamashita, Sato F, Matsushita S, Ohneda O, Sakakibara Y
- Organizer
  Cardiovascular Research Technologies
- Place of Presentation
  Washington, D.C
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] Hypoxia induciblefactor-3αの機能解析2009
- Author(s)
  小林里美, 山下年晴, 植田崇史, 中井秀人, 長野真澄, 大根田修
- Organizer
  第32回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] Hypoxia inducible factor-3αの機能解析2009
- Author(s)
  小林里美, 山下年晴, 植田崇史, 中井秀人, 長野真澄, 大根田修
- Organizer
  第七回がんとハイポキシア研究会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療と機能解析2009
- Author(s)
  秋本恵子, 木村健一, 長野真澄, 高野晋吾, 山下年晴, 大根田修
- Organizer
  平成21年度日本生化学会関東支部例会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] がん転移巣形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴, 長野真澄, 坪井一輝, 大根田修
- Organizer
  第七回がんとハイポキシア研究会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] がん転移形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴, 長野真澄, 坪井一輝, 大根田修
- Organizer
  第32回分子生物学学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] SDF-1とCXCR7はグリオーマの血管新生の重要な標的分子である2009
- Author(s)
  高野晋吾,山下年晴,長野真澄,大須賀覚,益子良太,大根田修
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] Mesenchymal stem cells is useful for cell therapy of glioblastoma multiforme2009
- Author(s)
  秋本恵子, 木村健一, 長野真澄, 高野晋吾, 山下年晴, 大根田修
- Organizer
  第32回分子生物学学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療に向けた研究開発2009
- Author(s)
  秋本恵子,木村健一,長野真澄,高野晋吾,山下年晴,大根田修
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] がん転移形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴, 長野真澄, 坪井一輝, 大根田修
- Organizer
  第32回分子生物学学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] Hypoxia inducible factor-3αの機能解析2009
- Author(s)
  小林里美, 山下年晴, 植田崇史, 中井秀人, 長野真澄, 大根田修
- Organizer
  第32回分子生物学学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] 治療効果の高い間葉系幹細胞の単離およびその機能解析2009
- Author(s)
  木村健一, 長野真澄, 山下年晴, 野澤大輔, 濱田洋実, 落合直之, 吉川裕之, 大根田修
- Organizer
  平成21年度日本生化学会関東支部例会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21790304
[Presentation] Hypoxia inducible factor-3αの機能解析2009
- Author(s)
  小林里美,山下年晴,植田崇史,中井秀人,長野真澄,大根田修
- Organizer
  第32回分子生物学学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] がん転移巣形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴,長野真澄,坪井一輝,大根田修
- Organizer
  第七回がんとハイポキシア研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] Hypoxia inducible factor-3αの機能解析2009
- Author(s)
  小林里美, 山下年晴, 植田崇史, 中井秀人, 長野真澄, 大根田修
- Organizer
  第七回がんとハイポキシア研究会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療と機能解析2009
- Author(s)
  秋本恵子, 木村健一, 長野真澄, 高野晋吾, 山下年晴, 大根田修
- Organizer
  平成21年度日本生化学会関東支部例会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] がん転移形成におけるHIF-2alphaの機能解析2009
- Author(s)
  山下年晴,長野真澄,坪井一輝,大根田修
- Organizer
  第32回分子生物学学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] ヒト脳腫瘍由来血管内皮細胞および間葉系幹細胞を用いた悪性脳腫瘍の遺伝子細胞療法2008
- Author(s)
  高野晋吾、大須賀覚、益子良太、塚田喜子、宮川牧子、松村明、秋本恵子、木村健一、長野真澄、山下年晴、大根田修
- Organizer
  第1回筑波大学次世代医療研究開発・教育統合(CREIL)センター公開シンポジウム
- Place of Presentation
  つくば
- Year and Date
  2008-01-23
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] ヒト脳腫瘍由来血管内皮細胞および間葉系幹細胞を用いた悪性脳腫瘍の遺伝子細胞療法.2008
- Author(s)
  高野晋吾、山下年晴、大根田修, ら
- Organizer
  第1回筑波大学次世代医療研究開発・教育統合(CREIL)センター公開シンポジウム
- Place of Presentation
  つくば
- Year and Date
  2008-01-23
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] The role of Chemokine, SDF-1 and CXCR4 in glioma angiogenesis and invasiveness : Interaction between glioma and glioma derived endothelial cells2008
- Author(s)
  Shingo Takano, Satoru Osuka, Ryota Mashiko, Osamu Ohneda, Masumi Nagano, Toshiharu Yamashita, Akira Matsumura
- Organizer
  The 17^<th> International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Hakodate
- Year and Date
  2008-06-09
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] 生体内におけるHIF-3・/IPAS発現部位の同定2008
- Author(s)
  植田崇史,山下年晴,中井秀人,長野真澄,大根田修
- Organizer
  第6回がんとハイポキシア研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] グリオブラストーマにおけるHIF-2αの役割2008
- Author(s)
  秋本恵子、木村健一、長野真澄、高野晋吾、山下年晴、大根田修
- Organizer
  第6回がんとハイポキシア研究会
- Place of Presentation
  広島
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] The role of Chemokine, SDF-1 and CXCR4 in glioma angiogenesis and invasiveness: Interaction between glioma and glioma derive dendothelial cells. (June 9, Hakodate)2008
- Author(s)
  Takano S, Yamashita T et al.
- Organizer
  The 17th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Hakodate
- Year and Date
  2008-06-09
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] A Chemokine Receptor CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation of HIF-2a2008
- Author(s)
  Masumi Nagano, Ken-ichi Kimura, Toshiharu Yamashita, Hiromi Hamada,Kinuko Ohneda,Hiroyuki Yoshikawa, Osamu Ohneda
- Organizer
  50^<th> ASH Annual Meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] 虚血改善効果の高いヒト血管内皮前駆細胞における低酸素応答転写因子の機能解析2008
- Author(s)
  長野真澄,山下年晴,濱田洋実,大根田絹子,木村健一,中川智貴,吉川裕之,大根田修
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] グリオグラストーマにおけるHIF-2・の役割2008
- Author(s)
  秋本恵子,木村健一,長野真澄,高野晋吾,山下年晴,大根田修
- Organizer
  第6 回がんとハイポキシア研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] グリオーマ血管内皮細胞から考えたグリオーマの治療2008
- Author(s)
  高野晋吾、益子良太、長野真澄、山下年晴、大根田修、山本哲哉、坪井康次、松村明
- Organizer
  第35回ニューロオンコロジーの会
- Place of Presentation
  東京
- Year and Date
  2008-04-05
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] 赤血球分化における低酸素応答転写因子HIF-2・の機能解析2008
- Author(s)
  山下年晴,大根田絹子,大根田修
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] SDF-1・CXCR4を標的としたグリオーマの浸潤・血管新生同時抑制2008
- Author(s)
  高野晋吾、益子良太、大須賀覚、石川栄一、山本哲哉、山下年晴、大根田修、松村明
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  愛媛
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] グリオーマ血管内皮細胞から考えたグリオーマの治療.2008
- Author(s)
  高野晋吾、山下年晴ら
- Organizer
  第35回ニューロオンコゴジーの会
- Place of Presentation
  東京
- Year and Date
  2008-04-05
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] 赤血球分化における低酸素応答転写因子HIF-2alphaの機能解析2008
- Author(s)
  山下年晴, (他1名) 大根田修
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] グリオーマ血管新生におけるSDF-1/CXCR4ケモカインとグリオーマ由来血管内皮細胞の役割.2008
- Author(s)
  高野晋吾、山下年晴ら
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] SDF-1・CXCR4を標的としたグリオーマの浸潤・血管新生同時抑制.2008
- Author(s)
  高野晋吾、石川栄一、山下年晴ら
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  愛媛
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] HIF-3・による負の転写制御機構解明2008
- Author(s)
  山下年晴,植田崇史,長野真澄,大根田修
- Organizer
  第6回がんとハイポキシア研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] HIF-3aによる負の転写制御機構解明2008
- Author(s)
  山下年晴, (他2名) 大根田修
- Organizer
  第6回がんとハイポキシア研究会
- Place of Presentation
  広島市南区文化センター
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-20590876
[Presentation] 血管内皮前駆細胞を用いたtranslational research : グリオーマに対する抗血管新生療法2007
- Author(s)
  高野晋吾、大須賀覚、山本哲哉、坪井康次、松村明、大根田修、長野真澄、山下年晴
- Organizer
  第2回脳腫瘍基礎シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-01-20
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] 血管内皮前駆細胞を用いたグリオーマに対する血管新生抑制療法2006
- Author(s)
  高野晋吾、大根田修、山本哲哉、坪井康次、山下年晴、長野真澄、松村明
- Organizer
  第14回日本血管生物医学会
- Place of Presentation
  東京
- Year and Date
  2006-12-13
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] 血管内皮前駆細胞を用いたグリオーマに対する血管新生抑制療法2006
- Author(s)
  高野晋吾、大根田修、大須賀覚、山本哲哉、坪井康次、山下年晴、長野真澄、松村明
- Organizer
  第24回日本脳腫瘍学会
- Place of Presentation
  阿寒
- Year and Date
  2006-10-01
- Data Source
  KAKENHI-PROJECT-18591576
[Presentation] ステロイド薬投与による脂肪組織由来間葉系幹細胞への影響
- Author(s)
  加藤俊貴，木村健一，長野真澄，山下年晴，秋本恵子，三島初，大根田修
- Organizer
  日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24615002
[Presentation] ヒト間葉系幹細胞のグリオブラストーマ増殖抑制に対する作用機構解明
- Author(s)
  秋本恵子，木村健一，長野真澄，高野晋吾，山下年晴，大根田修
- Organizer
  日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24615002
[Presentation] 異なる歯組織形成段階における歯髄幹細胞の比較解析
- Author(s)
  菊地豪，山縣憲司，佐藤和聡，木村健一，山下年晴，大根田修
- Organizer
  日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24615002

1. OHNEDA Osamu (30311872)

# of Collaborated Projects: 7 results

# of Collaborated Products: 64 results
2. TAKANO Shingo (50292553)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
3. EMA Masatsugu (60359578)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NAGANO Masumi (30436282)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
5. 加藤幸成 (00571811)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KUBOTA YOshinori (50348687)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. VUONG CAT・KHANH (20816102)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. IMAGAWA Shigehiko (60231164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMIZU Takashi (00338782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ABEI Masato (20261802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SUZUKI Kensuke (20400674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 植田琢也 (40361448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松村明 (90241819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 鶴嶋英夫 (50315470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 松田和郎 (80444446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Hiramatsu Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Hamada Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. YAMAGATA Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. UENO Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. TAKASAKI Mami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 芝大

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# of Collaborated Products: 1 results
22. 近藤峰生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 大坂基男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashita Toshiharu 山下 年晴

YAMASHITA Toshiharu 山下 年晴

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Developmental mechanisms of glioblastoma-derived blood vessels and their effect on malignancyPrincipal Investigator

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Analysis of the effects of hypoxia inducible factor for tumor metastasisPrincipal Investigator

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A functional analysis of HIF for tumor metastasisPrincipal Investigator

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[Journal Article] Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues.2022

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[Journal Article] Type 2 Diabetes Mellitus Promotes the Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells into Cancer-Associated Fibroblasts, Induced by Breast Cancer Cells.2022

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Yamashita Toshiharu 山下年晴

YAMASHITA Toshiharu 山下年晴