Okunishi Katsuhide 奥西勝秀

… Alternative Names

OKUNISHI Katsuhide 奥西勝秀

奥西勝秀オクニシカツヒデ

Less

Researcher Number	50401112
Other IDs
Affiliation (Current)	2025: 東邦大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 群馬大学, 生体調節研究所, 准教授 2012 – 2019: 群馬大学, 生体調節研究所, 講師 2006: 東大, 医学部附属病院
Review Section/Research Field	Principal Investigator Collagenous pathology/Allergology / Basic Section 59040:Nutrition science and health science-related / Basic Section 54020:Connective tissue disease and allergy-related / Metabolomics / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator サイトカイン / 調節性分泌 / Rab27 / アレルギー / 肥満・糖尿病 / 肥満 / 免疫学 / 脂肪細胞 / ALK7 / GDF3 … More / 免疫細胞 / GDF3-ALK7経路 / アレルギー・ぜんそく / Th2サイトカイン / Th2 / 細胞・組織 / 糖尿病 / 喘息 / 細胞機能抑制 / 翻訳抑制 / T細胞 / 肺線維芽細胞 / マクロファージ / プロスタグランジンE2 Less

サイトカインを介した新奇肥満制御機構の解明Principal Investigator
- Principal Investigator
  
  奥西勝秀
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gunma University
Elucidation of the molecular basis for regulation of allergic immune responses by Rab27Principal Investigator
- Principal Investigator
  
  Okunishi Katsuhide
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Gunma University
Novel roles of Rab27 in cytokine signalingsPrincipal Investigator
- Principal Investigator
  
  Okunishi Katsuhide
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Gunma University
Novel roles of Rab27 and its effectors in allergic immune responsesPrincipal Investigator
- Principal Investigator
  
  OKUNISHI Katsuhide
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Gunma University
Roles of hepatocyte growth factor in obesity and diabetesPrincipal Investigator
- Principal Investigator
  
  OKUNISHI Katsuhide
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
抗原特異的免疫応答における肝細胞増殖因子の新たな役割に関する実験的研究Principal Investigator
- Principal Investigator
  
  奥西勝秀
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo

All 2024 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c+ antigen-presenting cells.2024
- Author(s)
  Okunishi K, Kochi Y, Zhao M, Wang H, Nakagome K, Izumi T
- Journal Title
  
  Allergy
  
  Volume: Online ahead of print Issue: 7 Pages: 1992-1995
- DOI
  10.1111/all.16087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08796, KAKENHI-PROJECT-23K23860, KAKENHI-PROJECT-23K27992
[Journal Article] Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses2020
- Author(s)
  Katsuhide Okunishi, Hao Wang, Maho Suzukawa, Ray Ishizaki, Eri Kobayashi, Miho Kihara, Takaya Abe, Jun-ichi Miyazaki, Masafumi Horie, Akira Saito, Hirohisa Saito, Susumu Nakae, Tetsuro Izumi
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: - Issue: 7 Pages: 3919-3935
- DOI
  10.1172/jci127839
- NAID
  40022605127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09994, KAKENHI-PROJECT-20K08796, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-19H03449, KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-20K15742
[Journal Article] Melanophilin accelerates insulin granule fusion without predocking to the plasma membrane.2020
- Author(s)
  Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T.
- Journal Title
  
  Diabetes
  
  Volume: 69 Issue: 12 Pages: 2655-2666
- DOI
  10.2337/db20-0069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07280, KAKENHI-PROJECT-20K08796, KAKENHI-PROJECT-20K08866, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-20H00480, KAKENHI-PROJECT-19H03449, KAKENHI-PROJECT-20K15742
[Journal Article] Distinct PKA regulatory subunits mediate PGE2 inhibition of TGFβ-1-stimulated collagen I translation and myofibroblast differentiation2017
- Author(s)
  Wettlaufer Scott H.、Penke L. Raghu、Okunishi Katsuhide、Peters-Golden Marc
- Journal Title
  
  American Journal of Physiology-Lung Cellular and Molecular Physiology
  
  Volume: 313 Issue: 4 Pages: L722-L731
- DOI
  10.1152/ajplung.00131.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09994, KAKENHI-PROJECT-26461484
[Journal Article] Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa2017
- Author(s)
  Fan Fushun、Matsunaga Kohichi、Wang Hao、Ishizaki Ray、Kobayashi Eri、Kiyonari Hiroshi、Mukumoto Yoshiko、Okunishi Katsuhide、Izumi Tetsuro
- Journal Title
  
  eLife
  
  Volume: 6 Pages: 1-23
- DOI
  10.7554/elife.26174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09994, KAKENHI-PROJECT-15K08295, KAKENHI-PROJECT-26461484, KAKENHI-PROJECT-16K15211
[Journal Article] Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells2014
- Author(s)
  Zasłona Z, Okunishi K, Bourdonnay E, Domingo-Gonzalez R, Moore BB, Lukacs NW, Aronoff DM, Peters-Golden M
- Journal Title
  
  J. Allergy Clin. Immunol.
  
  Volume: 133 Issue: 2 Pages: 379-387
- DOI
  10.1016/j.jaci.2013.07.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890035
[Journal Article] Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions2014
- Author(s)
  Okunishi K, DeGraaf AJ, Zasłona Z, Peters-Golden M
- Journal Title
  
  FASEB J
  
  Volume: 28 Issue: 1 Pages: 56-66
- DOI
  10.1096/fj.13-231720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890035
[Journal Article] Perillyl alcohol suppresses antigen-induced immune responses in the lung2014
- Author(s)
  Imamura M, Sasaki O, Okunishi K, Nakagome K, Harada H, Kawahata K, Tanaka R, Yamamoto K, Dohi M
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 443 Issue: 1 Pages: 266-71
- DOI
  10.1016/j.bbrc.2013.11.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890035
[Journal Article] Reversal of myofibroblast differentiation by prostaglandin E22013
- Author(s)
  Garrison G, Huang SK, Okunishi K, Scott JP, Kumar Penke LR, Scruggs AM, Peters-Golden M
- Journal Title
  
  Am. J. Respir. Cell Mol. Biol.
  
  Volume: 48 Issue: 5 Pages: 550-558
- DOI
  10.1165/rcmb.2012-0262oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890035
[Journal Article] Alendronate attenuates eosinophilic airway inflammation associated with suppression of Th2 cytokines, Th17 cytokines, and eotaxin-2.2013
- Author(s)
  Oh Sasaki, Mitsuru Imamura, Yusuke Yamazumi, Hiroaki Harada, Taku Matsumoto, Katsuhide Okunishi, Kazuyuki Nakagome, Ryoichi Tanaka, Tetsu Akiyama, Kazuhiko Yamamoto　and Makoto Dohi
- Journal Title
  
  J. Immunol
  
  Volume: 191 Issue: 6 Pages: 2879-2889
- DOI
  10.4049/jimmunol.1300460
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-24890035, KAKENHI-PROJECT-25670138
[Presentation] Exophilin-5 regulates IL-33-mediated Th2 responses2020
- Author(s)
  Katsuhide Okunishi, Hao Wang, Maho Suzukawa, Ray Ishizaki, Susumu Nakae, Tetsuro Izumi
- Organizer
  第15 回生命医科学研究所ネットワーク国際シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K08796
[Presentation] A novel regulatory role of the Rab27 effector exophilin5 in allergic airway inflammation2019
- Author(s)
  Katsuhide Okunishi, Hao Wang, Maho Suzukawa, Susumu Nakae, Tetsuro Izumi
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09994
[Presentation] Rab27エフェクターexophilin-5のアレルギー性気道炎症における新奇の役割の解明2019
- Author(s)
  奥西　勝秀、王　昊、泉　哲郎
- Organizer
  第56回日本臨床分子医学会
- Data Source
  KAKENHI-PROJECT-17K09994
[Presentation] Rab27エフェクターexophilin-5のアレルギー反応における役割2019
- Author(s)
  奥西　勝秀、王　昊、泉　哲郎
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09994
[Presentation] インスリンのALK7依存的な脂肪蓄積作用の解明2018
- Author(s)
  奥西　勝秀、歩　云、泉　哲郎
- Organizer
  第32回日本糖尿病・肥満動物学会
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] Rab27エフェクターによる抗原特異的Th2応答の制御機構の解明2018
- Author(s)
  星野　圭司、奥西　勝秀、泉　哲郎
- Organizer
  第65回北関東医学会総会
- Data Source
  KAKENHI-PROJECT-17K09994
[Presentation] インスリンのALK7依存的な脂肪蓄積作用の解明2018
- Author(s)
  奥西　勝秀、歩　云、泉　哲郎
- Organizer
  第32回日本糖尿病・肥満動物学会
- Data Source
  KAKENHI-PROJECT-17K09994
[Presentation] 脂肪組織におけるALK7シグナルの生理的役割の解明2017
- Author(s)
  歩　云、奥西　勝秀、與五沢　里美、泉　哲郎
- Organizer
  日本糖尿病・肥満動物学会
- Place of Presentation
  はまぎんホールヴィアマーレ（横浜）
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] Rab27 effector exophilin5 regulates IL-33 signaling in allergic immune responses2017
- Author(s)
  Okunishi, Katsuhide
- Organizer
  第46回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K09994
[Presentation] インスリンはGDF3-ALK7経路を介して脂肪蓄積を亢進させる2017
- Author(s)
  奥西　勝秀、歩　云、與五沢　里美、泉　哲郎
- Organizer
  第38回日本肥満学会
- Data Source
  KAKENHI-PROJECT-17K09994
[Presentation] Rab27 effector exophilin5 regulates IL-33 signaling in allergic immune responses2017
- Author(s)
  Okunishi, Katsuhide
- Organizer
  第46回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] インスリンはGDF3-ALK7経路を介して脂肪蓄積を亢進させる2017
- Author(s)
  奥西　勝秀、歩　云、與五沢　里美、泉　哲郎
- Organizer
  第38回日本肥満学会
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] I型TGF-beta受容体ALK7に対するリガンドの発現細胞ならびにその発現誘導因子の探索2016
- Author(s)
  奥西　勝秀、與五沢　里美、泉　哲郎
- Organizer
  日本肥満学会
- Place of Presentation
  東京ファッションタウンビル（東京）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] 脂肪組織におけるALK7リガンド産生細胞及びその誘導因子の同定2016
- Author(s)
  歩　云、與五沢　里美、奥西　勝秀、泉　哲郎
- Organizer
  北関東医学会
- Place of Presentation
  群馬大学医学部刀城会館（前橋）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] 白色脂肪組織におけるALK7リガンドの探索2015
- Author(s)
  奥西　勝秀、與五沢　里美、泉　哲郎
- Organizer
  日本肥満学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] PGE2はT細胞上EP2受容体を介してアレルギー性気道炎症を抑制する2014
- Author(s)
  奥西　勝秀
- Organizer
  第26回日本アレルギー学会春季臨床大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PROJECT-26461484
[Presentation] プロスタグランジンE_2はT細胞上EP2受容体を介してアレルギー性気道炎症を抑制する2014
- Author(s)
  奥西勝秀
- Organizer
  日本アレルギー学会
- Place of Presentation
  京都国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24890035
[Presentation] プロスタグランジンE2はT細胞上EP2受容体を介してアレルギー性気道炎症を抑制する2014
- Author(s)
  奥西　勝秀
- Organizer
  日本アレルギー学会
- Place of Presentation
  京都　国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24890035
[Presentation] プロスタグランジンE2による肺線維芽細胞からのコラーゲン産生抑制の機序の解明2013
- Author(s)
  奥西　勝秀、DeGraaf AJ, Zaslona Z, Peters-Golden M.
- Organizer
  日本アレルギー学会
- Place of Presentation
  東京　ホテルニューオータニ
- Data Source
  KAKENHI-PROJECT-24890035
[Presentation] プロスタグランジンE_2による肺線維芽細胞からのコラーゲン産生抑制の機序の解明2013
- Author(s)
  奥西勝秀、Angela J DeGraaf, Zbigniew Zasłona, Marc Peters-Golden
- Organizer
  日本アレルギー学会
- Place of Presentation
  東京ホテルニューオータニ
- Data Source
  KAKENHI-PROJECT-24890035
[Presentation] プロスタグランジンE_2による蛋白翻訳抑制作用の発見及びその細胞内シグナル伝達経路の解明2012
- Author(s)
  奥西勝秀、Angela J DeGraaf, Zbigniew Zasłona, Marc Peters-Golden
- Organizer
  日本アレルギー学会
- Place of Presentation
  大阪大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24890035
[Presentation] プロスタグランジンE2による蛋白翻訳抑制作用の発見及びその細胞内シグナル伝達経路の解明2012
- Author(s)
  奥西　勝秀
- Organizer
  第62回日本アレルギー学会秋季学術大会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24890035

1. 高橋倫子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 秋山徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okunishi Katsuhide 奥西 勝秀

OKUNISHI Katsuhide 奥西 勝秀

奥西 勝秀 オクニシ カツヒデ

Research Projects

Research Products

Co-Researchers

サイトカインを介した新奇肥満制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular basis for regulation of allergic immune responses by Rab27Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel roles of Rab27 in cytokine signalingsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel roles of Rab27 and its effectors in allergic immune responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of hepatocyte growth factor in obesity and diabetesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗原特異的免疫応答における肝細胞増殖因子の新たな役割に関する実験的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c+ antigen-presenting cells.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Melanophilin accelerates insulin granule fusion without predocking to the plasma membrane.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct PKA regulatory subunits mediate PGE2 inhibition of TGFβ-1-stimulated collagen I translation and myofibroblast differentiation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Perillyl alcohol suppresses antigen-induced immune responses in the lung2014

Author(s)

Okunishi Katsuhide 奥西勝秀

OKUNISHI Katsuhide 奥西勝秀

奥西勝秀オクニシカツヒデ