UJIKE Makoto 氏家誠

… Alternative Names

氏家誠ウジケマコト

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Researcher Number	50415478
Other IDs
Affiliation (Current)	2025: 日本獣医生命科学大学, 獣医学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 日本獣医生命科学大学, 獣医学部, 准教授 2017 – 2021: 日本獣医生命科学大学, 獣医学部, 准教授 2013 – 2016: 日本獣医生命科学大学, 獣医学部, 講師 2012: 日本獣医生命科学大学, 獣医学部獣医学科獣医感染症学教室, 助教 2011 – 2012: 日本獣医生命科学大学, 獣医学部, 助教 … More 2010: 日本獣医生命科学大学, 獣医学部・獣医感染症学教室, 助教 2006: National Institute of Infectious Diseases, Virology III, Research scientist, SARSウイルスペプチドを用いた解析, 研究員 2005: 国立感染症研究所, ウイルス第3部, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Virology / Veterinary medical science Except Principal Investigator Drug development chemistry / Virology / Veterinary medical science / Biological Sciences
Keywords	Principal Investigator コロナウイルス / 抗ウイルス薬 / ワクチン開発 / 牛下痢症 / 牛コロナウイルス / 牛トロウイルス / 感染性下痢 / 牛 / ワクチン / トロウイルス … More / SAIDs / αグルコシダーゼ阻害薬 / コロナウイルス、ドラッグリポジショニング、 / ドラッグリポジショニング / 小胞体ステロイド系抗炎症剤 / 小胞体αグルコシダーゼ阻害剤 / DMVs / 新規糖鎖付加阻害薬 / ウイルス学 / 小胞体αグルコシダーゼ阻害薬 / 細胞内輸送 / 出芽 / 細胞内郵送シグナル / 構造蛋白質 / 細胞内輸送シグナル / 粒子形成 / 核外移行シグナル / 核移行シグナル / 小胞体回収シグナル / N蛋白質 / S蛋白質 / ウイルス粒子形成 / Heptad-Repeat / コレステロール付加ペプチド / Heptad-repeat / 細胞侵入 / HRP / 膜融合 / S 蛋白質 … More Except Principal Investigator プロテアーゼ / pseudotype / SARS-CoV / 細胞侵入機構 / S蛋白 / 抗ウイルス / 阻害剤 / 糖鎖 / ウイルス糖タンパク質 / 抗ウイルス薬 / endosome / cell entry / protease / spike protein / peptide inhibitor / VLP / 細胞侵入経路 / サーズコロナウイルス / エンドゾーム / エンドソーム / 細胞侵入 / 病原性発現機構 / 病原性発現 / ＰＲＣＶ / ＴＧＥＶ / 組織親和性 / 病原性 / 豚コロナウイルス / TMPRSS2 / SARSコロナウイルス / ウイルス放出 / 細胞融合 / コロナウイルス Less

Development of enterotropic bovine torovirus vector for control of infectious bovine diarrhea.Principal Investigator
- Principal Investigator
  
  氏家誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Nippon Veterinary and Life Science University
Elucidation of the mechanism of inhibition of coronavirus DMVs formation by approved drugs.Principal Investigator
- Principal Investigator
  
  Ujike Makoto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Nippon Veterinary and Life Science University
Screening of antiviral agents that avoid drug resistance by inhibiting virus-specific replication processes
- Principal Investigator
  
  HAKAMATA Wataru
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nihon University
Development of novel alpha-glucosidase inhibitors suppressing coronavirus replication.Principal Investigator
- Principal Investigator
  
  Ujike Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
Effects of proteases on the pathogenesis of porcine coronaviruses
- Principal Investigator
  
  Taguchi Fumihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
Assembly mechanisms of coronavirusesPrincipal Investigator
- Principal Investigator
  
  Ujike Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Nippon Veterinary and Life Science University
Development of endosome targeted peptide inhibitors against envelopedviruses via endosomal pathway.Principal Investigator
- Principal Investigator
  
  UJIKE Makoto
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Nippon Veterinary and Life Science University
SARS及びマウスコロナウイルスの細胞侵入の分子機構と病原性発現に関する研究
- Principal Investigator
  
  Taguchi Fumihiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nippon Veterinary and Life Science University
Molecular analysis of cell entry of SARS coronavirus
- Principal Investigator
  
  TAGUCHI Fumihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases

[Journal Article] Progress of research on coronaviruses and toroviruses in large domestic animals using reverse genetics systems2024
- Author(s)
  Ujike Makoto、Suzuki Tohru
- Journal Title
  
  The Veterinary Journal
  
  Volume: 305 Pages: 106122-106122
- DOI
  10.1016/j.tvjl.2024.106122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05542
[Journal Article] Evidence of the simultaneous replications of active viruses in specimens positive for multiple respiratory viruses2024
- Author(s)
  Kawase Miyuki、Suwa Reiko、Sugimoto Satoko、Kakizaki Masatoshi、Kume Yohei、Chishiki Mina、Ono Takashi、Okabe Hisao、Norito Sakurako、Ujike Makoto、Hosoya Mitsuaki、Hashimoto Koichi、Shirato Kazuya
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 12 Issue: 1
- DOI
  10.1128/spectrum.01920-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05542, KAKENHI-PROJECT-23K07935
[Journal Article] Single Amino Acid Substitution in the Receptor Binding Domain of Spike Protein Is Sufficient To Convert the Neutralization Profile between Ethiopian and Middle Eastern Isolates of Middle East Respiratory Coronavirus2023
- Author(s)
  Sugimoto Satoko、Kakizaki Masatoshi、Kawase Miyuki、Kawachi Kengo、Ujike Makoto、Kamitani Wataru、Sentsui Hiroshi、Shirato Kazuya
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 2
- DOI
  10.1128/spectrum.04590-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06441, KAKENHI-PROJECT-23K05542
[Journal Article] Trends of Mismatches in Real-Time RT-PCR Assays Developed by the National Institute of Infectious Diseases, Japan for Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 22023
- Author(s)
  Shirato Kazuya、Ujike Makoto、Kawase Miyuki
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 76 Issue: 3 Pages: 204-206
- DOI
  10.7883/yoken.JJID.2022.556
- ISSN
  1344-6304, 1884-2836
- Year and Date
  2023-05-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05542
[Journal Article] Reverse Genetics with a Full-Length Infectious cDNA Clone of Bovine Torovirus2022
- Author(s)
  Ujike Makoto、Etoh Yuka、Urushiyama Naoya、Taguchi Fumihiro、Asanuma Hideki、Enjuanes Luis、Kamitani Wataru
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 3
- DOI
  10.1128/jvi.01561-21
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06393
[Journal Article] Reduction of Cell Fusion by Deletion in the Hypervariable Region of the Spike Protein of Mouse Hepatitis Virus2022
- Author(s)
  Tennakoon Nipuna、Ryu Jihoon、Ujike Makoto、Taguchi Fumihiro、Shin Hyun-Jin
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 2 Pages: 398-398
- DOI
  10.3390/v14020398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06393
[Journal Article] Recent Progress in Torovirus Molecular Biology2021
- Author(s)
  Ujike Makoto、Taguchi Fumihiro
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 3 Pages: 435-435
- DOI
  10.3390/v13030435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06393
[Journal Article] The Inhaled Steroid Ciclesonide Blocks SARS-CoV-2 RNA Replication by Targeting the Viral Replication-Transcription Complex in Cultured Cells2020
- Author(s)
  Matsuyama Shutoku、Kawase Miyuki、Nao Naganori、Shirato Kazuya、Ujike Makoto、Kamitani Wataru、Shimojima Masayuki、Fukushi Shuetsu
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 1
- DOI
  10.1128/jvi.01648-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06393, KAKENHI-PROJECT-20K07519
[Journal Article] Characterization of Localization and Export Signals of Bovine Torovirus Nucleocapsid Protein Responsible for Extensive Nuclear and Nucleolar Accumulation and Their Importance for Virus Growth2020
- Author(s)
  Ujike Makoto、Kawachi Yukako、Matsunaga Yui、Etho Yuka、Asanuma Hideki、Kamitani Wataru、Taguchi Fumihiro
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 3
- DOI
  10.1128/jvi.02111-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06393
[Journal Article] A novel defective recombinant porcine enterovirus G virus carrying a porcine torovirus papain-like cysteine protease gene and a putative anti-apoptosis gene in place of viral structural protein genes.2019
- Author(s)
  Imai R, Nagai M, Oba M, Sakaguchi S, Ujike M, Kimura R, Kida M, Masuda T, Kuroda M, Wen R, Li K, Katayama Y, Naoi Y, Tsuchiaka S, Omatsu T, Yamazato H, Makino S, Mizutani T.
- Journal Title
  
  Infect Genet Evol.
  
  Volume: 75 Pages: 103975-103975
- DOI
  10.1016/j.meegid.2019.103975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06393
[Journal Article] Phylogenetic and antigenic characterization of newly isolated porcine epidemic diarrhea viruses in Japan.2016
- Author(s)
  Islam MT, Kubota T, Ujike M, Yahara Y, Taguchi F.
- Journal Title
  
  Virus Res
  
  Volume: 222 Pages: 113-9
- DOI
  10.1016/j.virusres.2016.06.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08032
[Journal Article] The contribution of the cytoplasmic retrieval signal of severe acute respiratory syndrome coronavirus to intracellular accumulation of S proteins and incorporation of S protein into virus-like particles.2016
- Author(s)
  Ujike M, Huang C, Shirato K, Makino S, Taguchi F.
- Journal Title
  
  J Gen Virol.
  
  Volume: 印刷中 Issue: 8 Pages: 1853-64
- DOI
  10.1099/jgv.0.000494
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860346, KAKENHI-PROJECT-16K08032
[Journal Article] Incorporation of spike and membrane glycoproteins into coronavirus virions.2015
- Author(s)
  Ujike M, Taguchi F
- Journal Title
  
  Viruses
  
  Volume: 7 Issue: 4 Pages: 1700-25
- DOI
  10.3390/v7041700
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25450431
[Journal Article] Identification of CCL2, RARRES2 and EFNB2 as host cell factors that influence the multistep replication of respiratory syncytial virus.2015
- Author(s)
  Shirato K, Ujike M, Kawase M, Matsuyama S.
- Journal Title
  
  Virus Res
  
  Volume: 210 Pages: 213-26
- DOI
  10.1016/j.virusres.2015.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860346
[Journal Article] Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan.2015
- Author(s)
  Ainai A, Hasegawa H, Obuchi M, Odagiri T, Ujike M, Shirakura M, Nobusawa E, Tashiro M, Asanuma H.
- Journal Title
  
  PLoS One
  
  Volume: 10(6): Issue: 6 Pages: 6066-6069
- DOI
  10.1371/journal.pone.0130208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860346, KAKENHI-PROJECT-25286062
[Journal Article] Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions.2015
- Author(s)
  Ujike M, Taguchi F
- Journal Title
  
  Viruses
  
  Volume: 7(4) Pages: 1700-1725
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860346
[Journal Article] Hemagglutination mediated by the spike protein of cell-adapted bovine torovirus2013
- Author(s)
  Shimabukuro K, Ujike M, Ito T, Tsunemitsu H, Oshitani H, Taguchi F
- Journal Title
  
  Arch. Virol.
  
  Volume: １５８ Issue: 7 Pages: 1561-1566
- DOI
  10.1007/s00705-013-1636-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450431, KAKENHI-PROJECT-25860346
[Journal Article] Mutation in the cytoplasmic retrieval signal of porcine epidemic diarrhea virus spike (S) protein is responsible for enhanced fusion activity.2012
- Author(s)
  Shirato K, Maejima M, Matsuyama S, Ujike M, Miyazaki A, Takeyama N, Ikeda H, Taguchi F.
- Journal Title
  
  Virus Res
  
  Volume: 161 Pages: 188-93
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S incorporation into virus-like particles, but not for M-S co-localization.2012
- Author(s)
  Ujike M
- Journal Title
  
  J. Gen. Virol
  
  Volume: 93 Issue: 4 Pages: 823-828
- DOI
  10.1099/vir.0.038091-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Increased replication of respiratory syncytial virus in the presence of cytokeratin 8 and 18.2012
- Author(s)
  Shirato K, Ujike M, Kawase M, Matsuyama S.
- Journal Title
  
  J Med Virol.
  
  Volume: 84 Issue: 2 Pages: 365-370
- DOI
  10.1002/jmv.23196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790509, KAKENHI-PROJECT-23791205
[Journal Article] Role of proteases in the release of porcine epidemic diarrhea virus from infected cells.2012
- Author(s)
  Shirato K, Matsuyama S, Ujike M, Taguchi F.
- Journal Title
  
  J Virol
  
  Volume: 85 Pages: 7872-80
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S incorporation into virus-like particles, but not for M-S co-localization.2012
- Author(s)
  Ujike M, Huang C, Shirato K, Matsuyama S, Makino S, Taguchi F.
- Journal Title
  
  J Gen Virol.
  
  Volume: 93 Pages: 823-8
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Increased replication of respiratory syncytial virus in the presence of cytokeratin8 and 18.2012
- Author(s)
  Shirato K, Ujike M, Kawase M, Matsuyama S.
- Journal Title
  
  J Med Virol.
  
  Volume: 84 Pages: 365-70
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Rapid discrimination of oseltamivir-resistant275Y and -susceptible 275H substitutions in the neuraminidase gene of pandemic influenza A/H1N1 2009 virus by duplex one-step RT-PCR assay.2011
- Author(s)
  Nakauchi M, Ujike M, 他10名
- Journal Title
  
  J Med Virol
  
  Volume: 83 Pages: 1121-7
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Monitoring and characterization of oseltamivir-resistant pandemic (H1N1) 2009 virus, Japan, 2009-2010.2011
- Author(s)
  Ujike M, Ejima M, Anraku A, 他13名
- Journal Title
  
  Emerg Infect Dis.
  
  Volume: 17 Pages: 470-9
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Mumefural and related HMF derivatives from Japanese apricot fruit juice concentrate show multiple inhibitory effects on pandemic influenza A (H1N1) virus.2011
- Author(s)
  Sriwilaijaroen N, Kadowaki A, Onishi Y, Gato N, Ujike M, Odagiri T, Tashiro M, Suzuki Y
- Journal Title
  
  Food Chemistry
  
  Volume: 127 Pages: 1-9
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Role of proteases in the release of porcine epidemic diarrhea virus from infected cells.2011
- Author(s)
  Shirato K, Matsuyama S, Ujike M, Taguchi F.
- Journal Title
  
  J Virol.
  
  Volume: 85 Issue: 15 Pages: 7872-7880
- DOI
  10.1128/jvi.00464-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Mutation in the cytoplasmic retrieval signal of porcine epidemic diarrhea virus spike (S) protein is responsible for enhanced fusion activity.2011
- Author(s)
  Shirato K, Maejima M, Matsuyama S, Ujike M, Miyazaki A, Takeyama N, Ikeda H, Taguchi F.
- Journal Title
  
  Virus Res.
  
  Volume: 161 Issue: 2 Pages: 188-193
- DOI
  10.1016/j.virusres.2011.07.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790509
[Journal Article] Enhancement of SARS-CoV infection by proteases.2006
- Author(s)
  Matsuyama S, Ujike M, Ishii I, Fukushi S, Morikawa S, Tashiro M, Taguchi F
- Journal Title
  
  Advances of Experimental Medicine and Biology 581
  
  Pages: 253-258
- Data Source
  KAKENHI-PROJECT-17390138
[Journal Article] Protease-mediated enhancement of SARS coronavirus infection.2005
- Author(s)
  Matsuyama S, Ujike M, Morikawa S, Tashiro M, Taguchi F.
- Journal Title
  
  Proc.Natl.Acad.Sci., U.S.A. 102
  
  Pages: 12543-12547
- Data Source
  KAKENHI-PROJECT-17390138
[Presentation] 牛トロウイルス粒子形成におけるヌクレオカプシドのNES領域の働き2023
- Author(s)
  氏家誠、淺原愛里、中尾美月、漆山尚也、田口文広、神谷亘
- Organizer
  第166回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K05542
[Presentation] 組換牛トロウイルスの血球凝集素‐エステラーゼ（HE）遺伝子の安定性に関する研究2021
- Author(s)
  酒井悠輔、荻原里奈、漆山尚也、江藤由佳、田口文広、神谷亘、氏家誠
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06393
[Presentation] EGFP遺伝子を保持する組換牛トロウイルスの特性とその遺伝子安定性に関する研究2021
- Author(s)
  淺原愛里, 漆山尚也、江藤由佳、田口文広、神谷亘、氏家誠
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06393
[Presentation] 牛トロウイルスにおけるReverse Genetics系の確立2020
- Author(s)
  江藤由佳、漆山尚也、田口文広、神谷亘、氏家誠
- Organizer
  第4回獣医微生物学フォーラム
- Data Source
  KAKENHI-PROJECT-19K06393
[Presentation] 牛トロウイルスのHemagglutinin‐Esterase（HE）遺伝子の安定性に関する研究2019
- Author(s)
  木暮茉希、江藤由佳、イスラム・タイムール、田口文広、氏家誠
- Organizer
  162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06393
[Presentation] 牛トロウイルスのメンブレン蛋白質の細胞内蓄積に関する研究2019
- Author(s)
  氏家誠、鈴木友美、田口文広、
- Organizer
  162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06393
[Presentation] 牛トロウイルスNucleocapsid(N)蛋白質のCRM1非依存的Nuclear export signal(NES)に関する研究2019
- Author(s)
  木村留華、木田萌子、岩田修二、松永惟、田口文広、氏家誠
- Organizer
  162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06393
[Presentation] 牛トロウイルスヌクレオカプシド蛋白質のCRM1非依存的核外移行シグナルに関する研究2018
- Author(s)
  木田萌子、木村留華、岩田修二、松永惟、田口文広、氏家誠
- Organizer
  第66回日本ウイルス学会学術集会(京都)
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] 牛トロウイルスの血球凝集素‐エステラーゼ（HE）遺伝子の安定性に関する研究2018
- Author(s)
  氏家誠、江藤由佳、木暮茉希、イスラム・タイムール、田口文広
- Organizer
  第66回日本ウイルス学会学術集会(京都)
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] 牛トロウイルスのMembrane(M)蛋白質の細胞内局在に関する研究2018
- Author(s)
  鈴木友美、田口文広、氏家誠
- Organizer
  第66回日本ウイルス学会学術集会(京都)
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] 牛トロウイルスヌクレオカプシド蛋白質の核輸送機構に関する研究2017
- Author(s)
  岩田修二、松永惟、河内悠華子、田口文広、氏家誠
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] 新規小胞体α-グルコシダーゼ阻害薬による抗コロナウイルス機構に関する研究2017
- Author(s)
  小酒さおり、坪内千春、上間駿、恩田桃子、松山州徳、袴田航、氏家誠
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] Inverse correlation between innate immune responses and pathogenicity of influenza H7N9 virus that is adapted to mice2017
- Author(s)
  Teruki Miyazaki, Kimimasa Takahashi, Makoto Ujike, Akira Ainai, Hideki Hasegawa, Noriyo Nagata, Takato Odagiri, Masato Tashiro, Hideki Asanuma
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] 牛トロウイルスN蛋白質の核輸送調節に関する研究2016
- Author(s)
  伊藤咲、松永惟、河内悠華子、田口文広、氏家誠
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源学部（神奈川県藤沢市）
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] 小胞体α-グルコシダーゼ阻害薬による抗コロナウイルス機構に関する研究2016
- Author(s)
  氏家誠、松永唯、荒井　詩織、松山州徳、袴田　航
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] Phylogenetic and antigenic characterization of newly isolated porcine epidemic diarrhea virus (PEDV) in Japan2016
- Author(s)
  Islam MT, Kubota T, Ujike M, Yahara Y, Taguchi F.
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  Sapporo convention center (Hokkaido, Sapporo )
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K08032
[Presentation] Analysis of biological function of Hemagglutinin-esterase protein of bovine torovirus2015
- Author(s)
  Islam T, Asahi M, Arita T, Tsunemitu H, Ujike M, Taguchi F
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（福岡市博多区石城町2‐1）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] Identification of the region in bovine torovirus N protein involved in nuclear transpot2015
- Author(s)
  Matsunaga Y, Kawachi Y, Taguchi F, Ujike
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（福岡市博多区石城町2‐1）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] バキュロウイルスを用いた牛トロウイルスの可溶性血球凝集素‐エステラーゼ蛋白質の発現と機能解析2015
- Author(s)
  河内健吾、氏家誠、谷英樹、森川茂、田口文広
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学獣医学部（青森県十和田市東23番町35－1）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] ウシトロウイルスN蛋白質の核移行に関する研究2015
- Author(s)
  松永惟、河内悠華子、田口文広、氏家誠
- Organizer
  63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（兵庫県淡路市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] 小胞体α-グルコシダーゼ阻害薬による抗コロナウイルス機構に関する研究2015
- Author(s)
  氏家誠、松永唯、荒井　詩織、松山州徳、袴田　航
- Organizer
  63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（兵庫県淡路市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] Analysis of biological function of Hemagglutinin-Esterase protein of bovine torovirus2015
- Author(s)
  Md. Taimur Islam, Motoi Asahi, Tsunehiko Aita、 Hiroshi Tsunemitsu, Makoto Ujike, Fumihiro Taguch
- Organizer
  63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（兵庫県淡路市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] Biological Characterization of Hemagglutinin-Esterase Protein (HE) of Bovine Torovirus2015
- Author(s)
  Md. Taimur Islam, Motoi Asahi, Ryo Ichikawa, Tsunehiko Aita, Hiroshi Tsunemitsu, Makoto Ujike, Fumihiro Taguchi
- Organizer
  第14回あわじしま感染症・免疫フォーラム
- Place of Presentation
  路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] サーズコロナウイルス(SCoV)の粒子形成におけるERretrieval signalの役割について2013
- Author(s)
  氏家誠、白戸憲也、松山州徳、田口文広
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] ウシトロウイルスの血球凝集‐エステラゼ（HE）蛋白質の血球凝集（HA）能について2013
- Author(s)
  朝日基、島袋梢、市川諒、会田恒彦、伊藤寿浩、恒光裕、氏家誠、田口文広
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] ウシトロウイルスS蛋白質内領域の細胞内輸送の役割について2013
- Author(s)
  氏家誠、島袋梢、田口文広
- Organizer
  第61回日本ウイルス学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] ウシトロウイルスS蛋白質の細胞質内領域の細胞内輸送における役割について2013
- Author(s)
  氏家誠、島袋梢、田口文広
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] ウシトロウイルスの血球凝集ーエステラゼ（HE）蛋白質の血球凝集（HA）能について2013
- Author(s)
  朝日基、島袋梢、市川諒、会田恒彦、伊藤寿浩、恒光裕、氏家誠、田口文広
- Organizer
  第156回日本獣医学会学術集
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] 牛トロウイルス構造蛋白質の細胞内局在に関する研究2013
- Author(s)
  八木ことえ、小田えりな、氏家誠、田口文
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] ウシトロウイルス（BToV）構造蛋白質の細胞内局在に関する研究2013
- Author(s)
  八木ことえ、小田えりな、氏家誠、田口文広
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] サースコロナウイルスの粒子形成におけるER retrieval signalの役割について2013
- Author(s)
  氏家誠、白戸憲也、松山州徳、田口文広
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] SARS-CoVの粒子形成におけるERretrieval signalの役割について2012
- Author(s)
  氏家誠、白戸憲也、松山州徳、田口文広
- Organizer
  第60回日本ウイルス学会学術集会大阪国際会議場
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23790509
[Presentation] Japanese apricot fruit juice concentrate contains anti-influenza compound, mumefural2012
- Author(s)
  Sriwilaijaroen N, Kadowaki A, Onishi Y, Gato N, Ujike M, Odagiri T, Tashiro M, Suzuki Y
- Organizer
  The 9th Japan-China InternationalConference of Virology
- Place of Presentation
  Sapporo Japan
- Data Source
  KAKENHI-PROJECT-23790509
[Presentation] SARS-CoVの粒子形成におけるERretrieval signalの役割について2012
- Author(s)
  氏家誠
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23790509
[Presentation] Role of proteases in porcine epidemic diarrhea virus infection in cultured cells2011
- Author(s)
  Shirato K, Matsuyama S, Ujike M, TaguchiF.
- Organizer
  XIIth International Nidovirus symposium.
- Place of Presentation
  Michigan, USA
- Data Source
  KAKENHI-PROJECT-23790509
[Presentation] ウシトロウイルスS蛋白質の細胞質内領域の細胞内輸送における役割
- Author(s)
  氏家誠、田口文広
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] ウシトロウイルスN蛋白質の核移行シグナルに関する研究
- Author(s)
  河内悠華子、八木ことえ、田口文広、氏家誠
- Organizer
  第157回日本獣医学会
- Place of Presentation
  北海道大学
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] ウシトロウイルスN蛋白質の核移行に関する研究
- Author(s)
  氏家誠、河内悠華子、八木ことえ、田口文広
- Organizer
  第62回日本ウイルス学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] Baculovirusを用いた牛Torovirus の可溶性Hemaggultinin-Esterase protein の発現
- Author(s)
  河内健吾、氏家誠、谷英樹、森川茂、田口文広
- Organizer
  第62回日本ウイルス学会総
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25450431
[Presentation] ウシトロウイルスS蛋白質の細胞質内領域の細胞内輸送における役割
- Author(s)
  氏家誠、田口文広
- Organizer
  第157 回日本獣医学会
- Place of Presentation
  北海道大学
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] ウシトロウイルスN蛋白質の核移行に関する研究
- Author(s)
  氏家誠、河内悠華子、八木ことえ、田口文広
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25860346
[Presentation] Baculovirusを用いた牛Torovirusの可溶性Hemaggultinin-Esteraseの発現
- Author(s)
  河内健吾, 石川涼子, 氏家誠, 谷英樹, 森川茂, 田口文広
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25860346

1. MATSUYAMA Shutoku (90373399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. Taguchi Fumihiro (30107429)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. HAKAMATA Wataru (10333337)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. NAKAGAKI Keiko (30421829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MORIKAWA Shigeru (00167686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. ISHII Koji (40280763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 鈴木亨 (10362188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 神谷亘 (60551421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. SHIRATO Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 石井孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UJIKE Makoto 氏家 誠

氏家 誠 ウジケ マコト

Research Projects

Research Products

Co-Researchers

Development of enterotropic bovine torovirus vector for control of infectious bovine diarrhea.Principal Investigator

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Elucidation of the mechanism of inhibition of coronavirus DMVs formation by approved drugs.Principal Investigator

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Screening of antiviral agents that avoid drug resistance by inhibiting virus-specific replication processes

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Development of novel alpha-glucosidase inhibitors suppressing coronavirus replication.Principal Investigator

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Effects of proteases on the pathogenesis of porcine coronaviruses

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Assembly mechanisms of coronavirusesPrincipal Investigator

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Development of endosome targeted peptide inhibitors against envelopedviruses via endosomal pathway.Principal Investigator

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SARS及びマウスコロナウイルスの細胞侵入の分子機構と病原性発現に関する研究

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Research Institution

Molecular analysis of cell entry of SARS coronavirus

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[Journal Article] Progress of research on coronaviruses and toroviruses in large domestic animals using reverse genetics systems2024

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[Journal Article] Evidence of the simultaneous replications of active viruses in specimens positive for multiple respiratory viruses2024

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[Journal Article] Single Amino Acid Substitution in the Receptor Binding Domain of Spike Protein Is Sufficient To Convert the Neutralization Profile between Ethiopian and Middle Eastern Isolates of Middle East Respiratory Coronavirus2023

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Data Source

[Journal Article] Trends of Mismatches in Real-Time RT-PCR Assays Developed by the National Institute of Infectious Diseases, Japan for Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 22023

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UJIKE Makoto 氏家誠

氏家誠ウジケマコト