Ohno Shinji 大野真治

… Alternative Names

OHNO Shinji 大野真治

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Researcher Number	50419529
Other IDs
Affiliation (Current)	2025: 琉球大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 琉球大学, 医学(系)研究科(研究院), 教授 2016: 琉球大学, 医学(系)研究科(研究院), 教授 2014 – 2015: 九州大学, 医学(系)研究科(研究院), 准教授 2006 – 2008: 九州大学, 大学院・医学研究院, 講師 2006: 九州大学, 大学院医学研究院, 講師
Review Section/Research Field	Principal Investigator Virology / Basic Section 49060:Virology-related / Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Biological Sciences / Virology
Keywords	Principal Investigator ヘルペスウイルス / 発がん / カポジ肉腫 / 古典型カポジ肉腫 / カポジ肉腫関連ヘルペスウイルス / ヒトヘルペスウイルス８ / 遺伝子発現 / 後期遺伝子 / ガンマヘルペスウイルス / CD150 … More / SSPE / 麻疹 / 微生物 / 感染症 / ウイルス … More Except Principal Investigator ウイルス受容体 / 麻疹ウイルス / パルボウイルスB19 / 急性心筋炎 / 宿主因子 / パルボウイルス / 心筋症 / 小児心筋炎 / タンパク質 / 膜融合 / ヘルペスウイルス / 蛋白質 / 微生物 / 感染症 / 免疫学 / ウイルス / CD150 / 組換えウイルス / 動物モデル / SLAM / 受容体 Less

ウイルス出芽第二経路の解明Principal Investigator
- Principal Investigator
  
  大野真治
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  University of the Ryukyus
Study on the etiology and its molecular pathogenesis of pediatric-onset myocarditis
- Principal Investigator
  
  大賀正一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyushu University
Effects of mutations in HHV8 isolated form Miyakojima island, Okinawa, JapanPrincipal Investigator
- Principal Investigator
  
  Ohno Shinji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  University of the Ryukyus
Herpesvirus switching mechanism of gene regulation.Principal Investigator
- Principal Investigator
  
  Ohno Shinji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  University of the Ryukyus
  Kyushu University
Interplay between viruses and their host cells
- Principal Investigator
  
  Yanagi Yusuke
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
CD150遺伝子改変マウスを用いたSSPEの病態の解明Principal Investigator
- Principal Investigator
  
  大野真治
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Kyushu University
Analysis of measles pathogenesis using the mouse model expressing measles virus receptor SLAM and recombinant viruses
- Principal Investigator
  
  YANAGI Yusuke
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  Kyushu University

All 2022 2021 2020 2019 2016 2015 2014 2013 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein2020
- Author(s)
  Ueo Ayako、Kubota Marie、Shirogane Yuta、Ohno Shinji、Hashiguchi Takao、Yanagi Yusuke
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 12
- DOI
  10.1128/jvi.00050-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07669
[Journal Article] Both type I and type III interferons are required to restrict measles virus growth in lung epithelial cells2019
- Author(s)
  Midori Taniguchi, Yusuke Yanagi, Shinji Ohno
- Journal Title
  
  Archives of Virology
  
  Volume: 164 Issue: 2 Pages: 439-446
- DOI
  10.1007/s00705-018-4087-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07669
[Journal Article] A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment2019
- Author(s)
  Guenther Thomas、Froehlich Jacqueline、Herrde Christina、Ohno Shinji、Burkhardt Lia、Adler Heiko、Grundhoff Adam
- Journal Title
  
  PLOS Pathogens
  
  Volume: 15 Issue: 10 Pages: e1007838-e1007838
- DOI
  10.1371/journal.ppat.1007838
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07669
[Journal Article] Trisaccharide containing alpha2,3-linked sialic acid is a receptor for mumps virus2016
- Author(s)
  Kubota M, Takeuchi K, Watanabe S, Ohno S, Matsuoka R, Kohda D, Nakakita S, Hiramatsu H, Suzuki Y, Nakayama T, Terada T, Shimizu K, Shimizu N, Shiroishi M, Yanagi Y, Hashiguchi T
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 113 Issue: 41 Pages: 11579-11584
- DOI
  10.1073/pnas.1608383113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-15J05685, KAKENHI-PROJECT-26713018
[Journal Article] Murine gammaherpesvirus 68 ORF35 is required for efficient lytic replication and latency2015
- Author(s)
  Shin-ichi Hikita, Yusuke Yanagi, Shinji Ohno
- Journal Title
  
  Journal of General Virology
  
  Volume: 96 Issue: 12 Pages: 3624-3634
- DOI
  10.1099/jgv.0.000310
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460558, KAKENHI-PLANNED-24115005
[Journal Article] Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region2015
- Author(s)
  Koga R, Sugita Y, Noda T, Yanagi Y, Ohno S.
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 20 Pages: 10524-10531
- DOI
  10.1128/jvi.01819-15
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-25293107, KAKENHI-PROJECT-26892028
[Journal Article] Measles Virus Mutants Possessing the Fusion Protein with Enhanced Fusion Activity Spread Effectively in Neuronal Cells, but Not in Other Cells, without Causing Strong Cytopathology2015
- Author(s)
  Watanabe S, Ohno S, Shirogane Y, Suzuki SO, Koga R, Yanagi Y.
- Journal Title
  
  J Virol
  
  Volume: 89 Issue: 5 Pages: 2710-2717
- DOI
  10.1128/jvi.03346-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24115005
[Journal Article] Measles Virus Nonstructural C Protein Modulates Viral RNA Polymerase Activity by Interacting with Host Protein SHCBP12013
- Author(s)
  Ito M, Iwasaki M, Takeda M, Nakamura T, Yanagi Y, Ohno S
- Journal Title
  
  J Virol
  
  Volume: 87 Issue: 17 Pages: 9633-9642
- DOI
  10.1128/jvi.00714-13
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24115005
[Journal Article] Measles virus receptors2009
- Author(s)
  Yanagi Y, Takeda M, Ohno S, Hashiguchi T.
- Journal Title
  
  Curr Top Microbiol Immunol 329
  
  Pages: 13-30
- Data Source
  KAKENHI-PROJECT-17209016
[Journal Article] Measles viruses possessing the polymerase protein genes of the Edmonston vaccine strain exhibit attenuated gene expression and growth in cultured cells and SLAM knock-in mice2008
- Author(s)
  Takeda M, Ohno S, Tahara M, Takeuchi H, Shirogane Y, Ohmura H, Nakamura T, Yanagi Y.
- Journal Title
  
  J Virol. 82
  
  Pages: 11979-11984
- Data Source
  KAKENHI-PROJECT-17209016
[Journal Article] Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection2007
- Author(s)
  Ohno S et al.
- Journal Title
  
  J Virol 81(4)
  
  Pages: 1650-1659
- Data Source
  KAKENHI-PROJECT-17209016
[Journal Article] Measles virus infection of SLAM(CD150)knockin mice reproduces tropism and immunosuppression in human infection2007
- Author(s)
  Ohno S, Ono N, Seki F, Takeda M, Kura S, Tsuzuki T, Yanagi Y.
- Journal Title
  
  J Virol. 81
  
  Pages: 1650-1659
- Data Source
  KAKENHI-PROJECT-17209016
[Journal Article] Measles Virus Infection of SLAM (CD150) Knockin Mice Reproduces Tropism and Immunosuppression in Human Infection2007
- Author(s)
  Ohno et al.
- Journal Title
  
  Journal of Virology 81
  
  Pages: 1650-1659
- Data Source
  KAKENHI-PROJECT-18790324
[Journal Article] Generation of measles virus with a segmented RNA genome2006
- Author(s)
  Takeda M, Nakatsu Y, Ohno S, Seki F, Tahara M, Hashiguchi T, Yanagi Y.
- Journal Title
  
  J Virol. 80
  
  Pages: 4242-4248
- Data Source
  KAKENHI-PROJECT-17209016
[Journal Article] Measles virus : cellular receptors, tropism and pathogenesis2006
- Author(s)
  Yanagi Y, Takeda M, Ohno S.
- Journal Title
  
  J Gen Virol. 87
  
  Pages: 2767-2779
- Data Source
  KAKENHI-PROJECT-17209016
[Journal Article] Efficient rescue of measles virus from cloned cDNA using SLAM-expressing Chinese hamster ovary cells2005
- Author(s)
  Takeda M, Ohno S, Seki F, Hashimoto K, Miyajima N, Takeuchi K, Yanagi Y.
- Journal Title
  
  Virus Res. 108
  
  Pages: 161-165
- Data Source
  KAKENHI-PROJECT-17209016
[Journal Article] Long untranslated regions of the measles virus M and F genes control virus replication and cytopathogenicity2005
- Author(s)
  Takeda M, Ohno S, Seki F, Nakatsu Y, Tahara M, Yanagi Y.
- Journal Title
  
  J Virol. 79
  
  Pages: 14346-14354
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] 沖縄県宮古島地方のKSHVがコードするORF42の機能解析2022
- Author(s)
  栗山和志, 渡部匡史, 大野真治
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07669
[Presentation] 沖縄県宮古島地方のKSHVがコードするORF72の機能解析2021
- Author(s)
  栗山和志, 渡部匡史, 大野真治
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07669
[Presentation] 神経細胞における麻疹ウイルスの伝播機構の解析2016
- Author(s)
  Yuma Sato, Shinji Ohno, Shumpei Watanabe, Yusuke Yanagi
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] 麻疹ウイルス感染における宿主因子Annexin A2の役割2016
- Author(s)
  Ritsuko Koga, Shinji Ohno, Yusuke Yanagi
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] アルファ2，3結合型シアル酸を含む末端三糖がムンプスウイルスの機能的受容体である2016
- Author(s)
  Marie Kubota, Kaoru Takeuchi, Shumpei Watanabe, Shinji Ohno, Rei Matsuoka, Daisuke Kohda, Shin-ichi Nakakita, Hiroaki Hiramatsu, Yasuo Suzuki, Tetsuo Nakayama, Tohru Terada, Kentaro Shimizu, Nobutaka Shimizu, Yusuke Yanagi, Takao Hashiguchi
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] Identification of a cellular protein contributing to the efficient growth of Murine gammaherpesvirus 682015
- Author(s)
  Ohno S, Yanagi Y
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] STING-/MAVS-dependent type I IFN induction triggered by measles virus fusion2015
- Author(s)
  Watanabe S, Ohno S, Glen M, Yanagi Y
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] Structural basis of the interaction between mumps virus HN protein and its receptor2015
- Author(s)
  Kubota M, Hashiguchi T, Watanabe S, Ohno S, Matsuoka R, Nakayama T,Hiramatsu H, Suzuki S, Yanagi Y, Takeuchi K
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] Identification of a cellular protein contributing to the efficient growth of Murine gammaherpesvirus 682015
- Author(s)
  Shinji Ohno，Yusuke Yanagi
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460558
[Presentation] 麻疹ウイルス増殖におけるCofilinの機能2014
- Author(s)
  古賀律子、大野真治、柳　雄介
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] 麻疹ウイルスHタンパク質による受容体認識の構造基盤2008
- Author(s)
  橋口隆生, 竹田誠, 田原舞乃, 池亀聡, 大野真治, 柳雄介
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] ポリメラーゼ遺伝子は麻疹ウイルスEdmonston株の弱毒化を担っている2008
- Author(s)
  竹田誠、大野真治、田原舞乃、白銀勇太、柳雄介
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] 宿主細胞の麻疹ウイルス感染認識機構と麻疹ウイルスVタンパク質の役割2008
- Author(s)
  池亀聡, 竹田誠, 大野真治, 中津祐一郎, 柳雄介
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] 麻疹ウイルスV蛋白質によるJAK-STAT経路の阻害メカニズムの解析2007
- Author(s)
  百田匡寿、大野真治、柳雄介
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] 肺癌細胞株を用いた麻疹ウイレスの新たな感染機構の解析2007
- Author(s)
  竹田誠、田原舞乃、橋口隆生、佐藤威、植木翔子、大野真治、柳雄介
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] 麻疹ウイルス感染におけるレセプターSLAM上の糖鎖の意義2007
- Author(s)
  橋口隆生、久保田万理恵、竹田誠、大野真治、柳雄介
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] 病原性麻疹ウイルスのV,C蛋白は独立して感染細胞のアポトーシスを抑制する2007
- Author(s)
  大野真治、柳雄介
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] Analysis of measles virus infection using human SLAM knock-in mice2006
- Author(s)
  Ohno S, Ono N, Seki F, Takeda M, Yanagi Y.
- Organizer
  The 6th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji Island, Hyogo
- Year and Date
  2006-09-06
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] ヒト SLAM ノックインマウスの麻疹ウイルス感染の解析2006
- Author(s)
  大野真治、小野伸之、関文緒、竹田誠、柳雄介
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Year and Date
  2006-11-21
- Data Source
  KAKENHI-PROJECT-17209016
[Presentation] Murine gammaherpesvirus 68のORF35蛋白質はウイルスの効率的な増殖や潜伏感染の成立に必要である
- Author(s)
  疋田伸一、柳雄介、大野真治
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26460558
[Presentation] マウスガンマヘルペスウイルス68のORF31の機能に重要なアミノ酸の同定
- Author(s)
  大野真治、柳雄介
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26460558
[Presentation] 膜融合能が亢進した麻疹ウイルスはIFN betaを強く誘導する
- Author(s)
  渡辺俊平、白銀勇太、大野真治、柳雄介
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-24115005
[Presentation] Murine gammaherpesvirus 68 open reading frame 31 protein plays an important role in late gene expression
- Author(s)
  Shinji Ohno and Yusuke Yanagi
- Organizer
  The 39th Annual International Herpesvirus Workshop
- Place of Presentation
  神戸
- Year and Date
  2014-07-19 – 2014-07-23
- Data Source
  KAKENHI-PROJECT-26460558

1. YANAGI Yusuke (40182365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
2. TAKEDA Makoto (40311401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
3. HASHIGUCHI Takao (50632098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. SUENAGA Tadahiro (20396675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 荒瀬尚 (10261900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大賀正一 (60233053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 今留謙一 (70392488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 井原健二 (80294932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 長谷川俊史 (90314806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ohno Shinji 大野 真治

OHNO Shinji 大野 真治

Research Projects

Research Products

Co-Researchers

ウイルス出芽第二経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the etiology and its molecular pathogenesis of pediatric-onset myocarditis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of mutations in HHV8 isolated form Miyakojima island, Okinawa, JapanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Herpesvirus switching mechanism of gene regulation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interplay between viruses and their host cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CD150遺伝子改変マウスを用いたSSPEの病態の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of measles pathogenesis using the mouse model expressing measles virus receptor SLAM and recombinant viruses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Both type I and type III interferons are required to restrict measles virus growth in lung epithelial cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trisaccharide containing alpha2,3-linked sialic acid is a receptor for mumps virus2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Murine gammaherpesvirus 68 ORF35 is required for efficient lytic replication and latency2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Measles Virus Mutants Possessing the Fusion Protein with Enhanced Fusion Activity Spread Effectively in Neuronal Cells, but Not in Other Cells, without Causing Strong Cytopathology2015

Author(s)

Journal Title

Ohno Shinji 大野真治

OHNO Shinji 大野真治