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Ohno Shinji  大野 真治

ORCIDConnect your ORCID iD *help
… Alternative Names

大野 真治  オオノ シンジ

OHNO Shinji  大野 真治

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Researcher Number 50419529
Other IDs
Affiliation (Current) 2020: 琉球大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help 2019: 琉球大学, 医学(系)研究科(研究院), 教授
2016: 琉球大学, 医学(系)研究科(研究院), 教授
2014 – 2015: 九州大学, 医学(系)研究科(研究院), 准教授
2006 – 2008: 九州大学, 大学院・医学研究院, 講師
2006: 九州大学, 大学院医学研究院, 講師
Review Section/Research Field
Principal Investigator
Virology / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Virology / Biological Sciences
Keywords
Principal Investigator
ヘルペスウイルス / ウイルス / 感染症 / 微生物 / 麻疹 / SSPE / CD150 / ガンマヘルペスウイルス / 後期遺伝子 / 遺伝子発現 / カポジ肉腫 / 発がん … More
Except Principal Investigator
… More 麻疹ウイルス / 受容体 / SLAM / 動物モデル / 組換えウイルス / ウイルス受容体 / CD150 / ウイルス / 免疫学 / 感染症 / 微生物 / 蛋白質 / ヘルペスウイルス / 膜融合 / タンパク質 Less
  • Research Projects

    (5 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (7 People)
  •  宮古島のHHV8にみられる遺伝子変異の意義Principal InvestigatorOngoing

    • Principal Investigator
      大野 真治
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      University of the Ryukyus
  •  Herpesvirus switching mechanism of gene regulation.Principal Investigator

    • Principal Investigator
      Ohno Shinji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      University of the Ryukyus
      Kyushu University
  •  Interplay between viruses and their host cells

    • Principal Investigator
      Yanagi Yusuke
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  CD150遺伝子改変マウスを用いたSSPEの病態の解明Principal Investigator

    • Principal Investigator
      大野 真治
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Kyushu University
  •  Analysis of measles pathogenesis using the mouse model expressing measles virus receptor SLAM and recombinant viruses

    • Principal Investigator
      YANAGI Yusuke
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Virology
    • Research Institution
      Kyushu University

All 2016 2015 2014 2013 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] Trisaccharide containing α2,3-linked sialic acid is a receptor for mumps virus2016

    • Author(s)
      Kubota M, Takeuchi K, Watanabe S, Ohno S, Matsuoka R, Kohda D, Nakakita S, Hiramatsu H, Suzuki Y, Nakayama T, Terada T, Shimizu K, Shimizu N, Shiroishi M, Yanagi Y, Hashiguchi T
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113 Pages: 11579-11584

    • DOI

      10.1073/pnas.1608383113

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-15J05685, KAKENHI-PROJECT-26713018
  • [Journal Article] Measles Virus Mutants Possessing the Fusion Protein with Enhanced Fusion Activity Spread Effectively in Neuronal Cells, but Not in Other Cells, without Causing Strong Cytopathology2015

    • Author(s)
      Watanabe S, Ohno S, Shirogane Y, Suzuki SO, Koga R, Yanagi Y.
    • Journal Title

      J Virol

      Volume: 89 Pages: 2710-2717

    • DOI

      10.1128/jvi.03346-14

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Journal Article] Murine gammaherpesvirus 68 open reading frame 35 is required for efficient lytic replication and latency2015

    • Author(s)
      Shin-ichi Hikita, Yusuke Yanagi, Shinji Ohno
    • Journal Title

      J Gen Virol

      Volume: 96 Pages: 3624-3634

    • DOI

      10.1099/jgv.0.000310

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460558, KAKENHI-PLANNED-24115005
  • [Journal Article] Actin-modulating protein cofilin is involved in the formation of Measles virus ribonucleoprotein complex at the perinuclear region2015

    • Author(s)
      Koga R, Sugita Y, Noda T, Yanagi Y, Ohno S.
    • Journal Title

      J Virol

      Volume: 89 Pages: 10524-10531

    • DOI

      10.1128/jvi.01819-15

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-25293107, KAKENHI-PROJECT-26892028
  • [Journal Article] Measles Virus Nonstructural C Protein Modulates Viral RNA Polymerase Activity by Interacting with Host Protein SHCBP12013

    • Author(s)
      Ito M, Iwasaki M, Takeda M, Nakamura T, Yanagi Y, Ohno S
    • Journal Title

      J Virol

      Volume: 87 Pages: 9633-9642

    • DOI

      10.1128/jvi.00714-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Journal Article] Measles virus receptors2009

    • Author(s)
      Yanagi Y, Takeda M, Ohno S, Hashiguchi T.
    • Journal Title

      Curr Top Microbiol Immunol 329

      Pages: 13-30

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Journal Article] Measles viruses possessing the polymerase protein genes of the Edmonston vaccine strain exhibit attenuated gene expression and growth in cultured cells and SLAM knock-in mice2008

    • Author(s)
      Takeda M, Ohno S, Tahara M, Takeuchi H, Shirogane Y, Ohmura H, Nakamura T, Yanagi Y.
    • Journal Title

      J Virol. 82

      Pages: 11979-11984

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Journal Article] Measles Virus Infection of SLAM (CD150) Knockin Mice Reproduces Tropism and Immunosuppression in Human Infection2007

    • Author(s)
      Ohno et al.
    • Journal Title

      Journal of Virology 81

      Pages: 1650-1659

    • Data Source
      KAKENHI-PROJECT-18790324
  • [Journal Article] Measles virus infection of SLAM(CD150)knockin mice reproduces tropism and immunosuppression in human infection2007

    • Author(s)
      Ohno S, Ono N, Seki F, Takeda M, Kura S, Tsuzuki T, Yanagi Y.
    • Journal Title

      J Virol. 81

      Pages: 1650-1659

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Journal Article] Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection2007

    • Author(s)
      Ohno S et al.
    • Journal Title

      J Virol 81(4)

      Pages: 1650-1659

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Journal Article] Measles virus : cellular receptors, tropism and pathogenesis2006

    • Author(s)
      Yanagi Y, Takeda M, Ohno S.
    • Journal Title

      J Gen Virol. 87

      Pages: 2767-2779

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Journal Article] Generation of measles virus with a segmented RNA genome2006

    • Author(s)
      Takeda M, Nakatsu Y, Ohno S, Seki F, Tahara M, Hashiguchi T, Yanagi Y.
    • Journal Title

      J Virol. 80

      Pages: 4242-4248

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Journal Article] Efficient rescue of measles virus from cloned cDNA using SLAM-expressing Chinese hamster ovary cells2005

    • Author(s)
      Takeda M, Ohno S, Seki F, Hashimoto K, Miyajima N, Takeuchi K, Yanagi Y.
    • Journal Title

      Virus Res. 108

      Pages: 161-165

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Journal Article] Long untranslated regions of the measles virus M and F genes control virus replication and cytopathogenicity2005

    • Author(s)
      Takeda M, Ohno S, Seki F, Nakatsu Y, Tahara M, Yanagi Y.
    • Journal Title

      J Virol. 79

      Pages: 14346-14354

    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] 麻疹ウイルス感染における宿主因子Annexin A2の役割2016

    • Author(s)
      Ritsuko Koga, Shinji Ohno, Yusuke Yanagi
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] アルファ2,3結合型シアル酸を含む末端三糖がムンプスウイルスの機能的受容体である2016

    • Author(s)
      Marie Kubota, Kaoru Takeuchi, Shumpei Watanabe, Shinji Ohno, Rei Matsuoka, Daisuke Kohda, Shin-ichi Nakakita, Hiroaki Hiramatsu, Yasuo Suzuki, Tetsuo Nakayama, Tohru Terada, Kentaro Shimizu, Nobutaka Shimizu, Yusuke Yanagi, Takao Hashiguchi
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] 神経細胞における麻疹ウイルスの伝播機構の解析2016

    • Author(s)
      Yuma Sato, Shinji Ohno, Shumpei Watanabe, Yusuke Yanagi
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] Identification of a cellular protein contributing to the efficient growth of Murine gammaherpesvirus 682015

    • Author(s)
      Ohno S, Yanagi Y
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-23
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] STING-/MAVS-dependent type I IFN induction triggered by measles virus fusion2015

    • Author(s)
      Watanabe S, Ohno S, Glen M, Yanagi Y
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-23
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] Structural basis of the interaction between mumps virus HN protein and its receptor2015

    • Author(s)
      Kubota M, Hashiguchi T, Watanabe S, Ohno S, Matsuoka R, Nakayama T,Hiramatsu H, Suzuki S, Yanagi Y, Takeuchi K
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-23
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] Identification of a cellular protein contributing to the efficient growth of Murine gammaherpesvirus 682015

    • Author(s)
      Shinji Ohno,Yusuke Yanagi
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460558
  • [Presentation] 麻疹ウイルス増殖におけるCofilinの機能2014

    • Author(s)
      古賀律子、大野真治、柳 雄介
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-11
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] 宿主細胞の麻疹ウイルス感染認識機構と麻疹ウイルスVタンパク質の役割2008

    • Author(s)
      池亀聡, 竹田誠, 大野真治, 中津祐一郎, 柳雄介
    • Organizer
      第56回 日本ウイルス学会
    • Place of Presentation
      岡山
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] ポリメラーゼ遺伝子は麻疹ウイルスEdmonston株の弱毒化を担っている2008

    • Author(s)
      竹田誠、大野真治、田原舞乃、白銀勇太、柳雄介
    • Organizer
      第56回日本ウイルス学会
    • Place of Presentation
      岡山
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] 麻疹ウイルスHタンパク質による受容体認識の構造基盤2008

    • Author(s)
      橋口隆生, 竹田誠, 田原舞乃, 池亀聡, 大野真治, 柳雄介
    • Organizer
      第56回 日本ウイルス学会
    • Place of Presentation
      岡山
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] 麻疹ウイルス感染におけるレセプターSLAM上の糖鎖の意義2007

    • Author(s)
      橋口 隆生、久保田 万理恵、竹田 誠、大野 真治、柳 雄介
    • Organizer
      第55回日本ウイルス学会
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] 麻疹ウイルスV蛋白質によるJAK-STAT経路の阻害メカニズムの解析2007

    • Author(s)
      百田 匡寿、大野 真治、柳 雄介
    • Organizer
      第55回日本ウイルス学会
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] 病原性麻疹ウイルスのV,C蛋白は独立して感染細胞のアポトーシスを抑制する2007

    • Author(s)
      大野 真治、柳 雄介
    • Organizer
      第55回日本ウイルス学会
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] 肺癌細胞株を用いた麻疹ウイレスの新たな感染機構の解析2007

    • Author(s)
      竹田 誠、田原 舞乃、橋口 隆生、佐藤 威、植木 翔子、大野 真治、柳 雄介
    • Organizer
      第55回日本ウイルス学会
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] ヒト SLAM ノックインマウスの麻疹ウイルス感染の解析2006

    • Author(s)
      大野真治、小野伸之、関文緒、竹田誠、柳雄介
    • Organizer
      第54回日本ウイルス学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-11-21
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] Analysis of measles virus infection using human SLAM knock-in mice2006

    • Author(s)
      Ohno S, Ono N, Seki F, Takeda M, Yanagi Y.
    • Organizer
      The 6th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Island, Hyogo
    • Year and Date
      2006-09-06
    • Data Source
      KAKENHI-PROJECT-17209016
  • [Presentation] マウスガンマヘルペスウイルス68のORF31の機能に重要なアミノ酸の同定

    • Author(s)
      大野真治、柳雄介
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-26460558
  • [Presentation] Murine gammaherpesvirus 68のORF35蛋白質はウイルスの効率的な増殖や 潜伏感染の成立に必要である

    • Author(s)
      疋田伸一、柳雄介、大野真治
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-26460558
  • [Presentation] 膜融合能が亢進した麻疹ウイルスはIFN betaを強く誘導する

    • Author(s)
      渡辺俊平、白銀勇太、大野真治、柳雄介
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PLANNED-24115005
  • [Presentation] Murine gammaherpesvirus 68 open reading frame 31 protein plays an important role in late gene expression

    • Author(s)
      Shinji Ohno and Yusuke Yanagi
    • Organizer
      The 39th Annual International Herpesvirus Workshop
    • Place of Presentation
      神戸
    • Year and Date
      2014-07-19 – 2014-07-23
    • Data Source
      KAKENHI-PROJECT-26460558
  • 1.  YANAGI Yusuke (40182365)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 2.  TAKEDA Makoto (40311401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 3.  HASHIGUCHI Takao (50632098)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  SUENAGA Tadahiro (20396675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  荒瀬 尚 (10261900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  野田 岳志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  杉田 征彦(杉田征彦)
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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