MIYAMOTO Yuki 宮本幸

… Alternative Names

宮本幸ミヤモトユキ

Miyamoto Yuki 宮本幸

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Researcher Number	50425708
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 薬剤治療研究部, 研究員
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人国立成育医療研究センター, 薬剤治療研究部, 研究員 2018 – 2019: 国立研究開発法人国立成育医療研究センター, 薬剤治療研究部, 研究員 2017: 国立研究開発法人国立成育医療研究センター, その他部局等, その他 2016: 国立研究開発法人国立成育医療研究センター, 薬剤治療研究部, 研究員 2015: 国立研究開発法人国立成育医療研究センター, その他部局等, 研究員 … More 2014: 独立行政法人国立成育医療研究センター, その他部局等, 研究員 2007: 国立成育医療セ 2006: 国立成育医療センター(研究所), 薬剤治療研究部, 共同研究員 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Basic Section 51030:Pathophysiologic neuroscience-related / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator オリゴデンドロサイト / 共培養 / ミエリン / グリア細胞 / 髄鞘 / 共培養系 / 大脳白質形成不全症 / claudin11 / 疾患モデルマウス / 大脳白質不全症 … More / ミエリン変性症 / 細胞間相互作用 / 神経細胞 / 分子神経科学 / Rhoファミリー / グアニンヌクレオチド交換因子 / 末梢神経 / DRG神経細胞 / シュワン細胞 Less

Elucidation of the pathophysiological mechanism of demyelinating neuropathies using a novel co-culture modelPrincipal Investigator
- Principal Investigator
  
  宮本幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  National Center for Child Health and Development
Elucidation of the molecular network that controls myelinationPrincipal Investigator
- Principal Investigator
  
  Miyamoto Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center for Child Health and Development
FROM THE QUESTION OF HOW GLIAL CELLS WRAP THEIR MEMBRANE WITH AXONS TO THE POSSIBLE SOLUTION OF HOW DEMYELINATING DISORDERS WERE RECOVEREDPrincipal Investigator
- Principal Investigator
  
  Miyamoto Yuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center for Child Health and Development
末梢神経の初期発生過程とその病態形成のシグナル伝達Principal Investigator
- Principal Investigator
  
  宮本幸
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Research Institute for Child Health and Development

All 2024 2023 2019 2018 2017 2016 2015 2014 2007 2006

All Journal Article Presentation

[Journal Article] Autism spectrum disorder-and/or intellectual disability-associated Semaphorin-5A exploits the mechanism by which Dock5 signalsome molecules control cell shape.2024
- Author(s)
  Miyu Okabe, Takanari Sato, Mikito Takahashi, Asahi Honjo, Maho Okawa Miki Ishida, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Curr. Issues Mol. Biol.
  
  Volume: 46 Issue: 4 Pages: 3092-3107
- DOI
  10.3390/cimb46040194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Rab11a controls cell shape via C9orf72 protein: possible relationships to frontotemporal dementia/amyotrophic lateral scleorosis (FTDALS) type 1.2024
- Author(s)
  Shoya Fukatsu, Hinami Sashi, Remina Shirai, Norio Takagi, Hiroaki Oizumi, Masahiro Yamamoto, Katsuya Ohbuchi, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Pathophysiology
  
  Volume: 31 Issue: 1 Pages: 100-116
- DOI
  10.3390/pathophysiology31010008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Modulating Golgi stress signaling ameliorates cell morphological phenotypes induced by CHMP2B with frontotemporal dementia-associated p.Asp148Tyr.2024
- Author(s)
  Shoya Fukatsu, Maho Okawa, Miyu Okabe, Mikinori Isogai, Takanori Yokoi, Remina Shirai, Hiroaki Oizumi, Masahiro Yamamoto, Katsuya Ohbuchi, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Curr. Issues Mol. Biol.
  
  Volume: 46 Issue: 2 Pages: 1398-1412
- DOI
  10.3390/cimb46020090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Lethal Adulthood Myelin Breakdown by Oligodendrocyte-specific Ddx54 Knockout2023
- Author(s)
  Oizumi H, Miyamoto Y, Seiwa C, Yamamoto M, Yoshioka N, Iizuka S, Torii T, Ohbuchi K, Mizoguchi K, Yamauchi J, Asou H
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 10 Pages: 107448-107448
- DOI
  10.1016/j.isci.2023.107448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15912, KAKENHI-PROJECT-23K06317, KAKENHI-PROJECT-23K06821
[Journal Article] FTD/ALS type7-associated Thr104Asn mutation of CHMP2B blunts neuronal process elongation, and is recovered by knockdown of Arf4, the Golgi stress regulator.2023
- Author(s)
  Remina Shirai, Mizuka Cho, Mikinori Isogai, Shoya Fukatsu, Miyu Okabe, Maho Okawa, Yuki Miyamoto, Tomohiro Torii, and Junji Yamauchi
- Journal Title
  
  Neurol. Int.
  
  Volume: 15 Issue: 3 Pages: 980-993
- DOI
  10.3390/neurolint15030063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Defective oligodendrocyte differentiation by hypomyelinating leukodystrophy 13 (HLD13)-associated mutation of Hikeshi.2023
- Author(s)
  Yuki Miyamoto, Kohei Hattori, and Junji Yamauchi
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 37 Pages: 101017-101017
- DOI
  10.1016/j.ymgmr.2023.101017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.2023
- Author(s)
  Miku Fukawa, Remina Shirai, Tomohiro Torii, Kenta Nakata, Shoya Fukatsu, Takanori Sato, Keiichi Homma, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 664 Pages: 50-58
- DOI
  10.1016/j.bbrc.2023.04.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Knockdown of Rab7B, but not of Rab7A, which antagonistically regulates oligodendroglial cell morphological differentiation, recovers tunicamycin-induced defective differentiation in FBD-102b cells.2023
- Author(s)
  Nana Fukushima, Remina Shirai, Takanori Sato, Sayumi Nakamura, Arisa Ochiai, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  J. Mol. Neurosci.
  
  Volume: 73 Issue: 6 Pages: 363-374
- DOI
  10.1007/s12031-023-02117-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Investigating the protective effects of a citrus flavonoid on the retardation morphogenesis of the oligodendroglia-like cell line by Rnd2 knockdown.2023
- Author(s)
  Shoya Fukatsu, Yuki Miyamoto, Yu Oka, Maki Ishibashi, Remina Shirai, Yuki Ishida, Shin Endo, Hironori Katoh, and Junji Yamauchi
- Journal Title
  
  Neurol. Int.
  
  Volume: 16 Issue: 1 Pages: 33-61
- DOI
  10.3390/neurolint16010003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06821, KAKENHI-PROJECT-21K06065
[Journal Article] RhoG-binding domain of Elmo1 ameliorates excessive process elongation induced by autism spectrum disorder-associated Sema5A.2023
- Author(s)
  Miyu Okabe, Yuki Miyamoto, Yuta Ikoma, Mikito Takahashi, Remina Shirai, Mutsuko Kukimoto-Niino, Mikako Shirouzu, and Junji Yamauchi
- Journal Title
  
  Pathophysiology
  
  Volume: 30 Issue: 4 Pages: 548-566
- DOI
  10.3390/pathophysiology30040040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06821
[Journal Article] Data on the effects of Charcot-Marie-Tooth disease type 2N-associated AARS missense mutation (Arg329-to-His) on the cell biological properties.2019
- Author(s)
  Imaizumi N, Takeuchi Y, Hirano H, Torii T, Seki Y, Morimoto T, Miyamoto Y, Sakagami H, Yamauchi J.
- Journal Title
  
  Data Brief
  
  Volume: 25 Pages: 104029-104029
- DOI
  10.1016/j.dib.2019.104029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564, KAKENHI-PROJECT-17K07127
[Journal Article] Cellular signal-regulated Schwann cell myelination and remyelination.2019
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Adv. Exp. Med. Biol.
  
  Volume: 1190 Pages: 3-22
- DOI
  10.1007/978-981-32-9636-7_1
- ISBN
  9789813296350, 9789813296367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07127
[Journal Article] Hypomyelinating leukodystrophy-associated mutation of RARS leads it to the lysosome, inhibiting oligodendroglial morphological differentiation.2019
- Author(s)
  Matsumoto N, Watanabe N, Iibe N, Tatsumi Y, Hattori K, Takeuchi Y, Oizumi H, Ohbuchi K, Torii T, Miyamoto Y, Yamauchi J.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 20 Pages: 100705-100705
- DOI
  10.1016/j.bbrep.2019.100705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564, KAKENHI-PROJECT-17K07127
[Journal Article] Defective neuronal and oligodendroglial differentiation by FTD3- and ALS17-associated Ile29-to-Val mutation of CHMP2B.2019
- Author(s)
  Minami Yamawaki, Masumi Akiba, Naoto Matsumoto, Natsumi Watanabe, Kohei Hattori, Yu Takeuchi, Takako Morimoto, Hiroaki Oizumi, Katsuya Ohbuchi, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 19 Pages: 100458-100458
- DOI
  10.1016/j.ymgmr.2019.100458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127
[Journal Article] CMT type 2N disease-associated AARS mutant inhibits neurite growth that can be reversed by valproic acid2019
- Author(s)
  Tatsumi Yuriko、Matsumoto Naoto、Iibe Noriko、Watanabe Natsumi、Torii Tomohiro、Sango Kazunori、Homma Keiichi、Miyamoto Yuki、Sakagami Hiroyuki、Yamauchi Junji
- Journal Title
  
  Neuroscience Research
  
  Volume: 139 Pages: 69-78
- DOI
  10.1016/j.neures.2018.09.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-17H03564, KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-16K07048
[Journal Article] Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure.2018
- Author(s)
  Miyamoto Y, Torii T, Inoue M, Morimoto T, Yamamoto M, Yamauchi J
- Journal Title
  
  Data Brief
  
  Volume: 18 Pages: 803-807
- DOI
  10.1016/j.dib.2018.03.099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127
[Journal Article] BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice.2018
- Author(s)
  Miyamoto Y, Torii T, Tago K, Tanoue A, Takashima S, Yamauchi J
- Journal Title
  
  Sci Adv.
  
  Volume: 4 Issue: 4
- DOI
  10.1126/sciadv.aar4471
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17H03564
[Journal Article] Dystonia-4 (DYT4)-associated TUBB4A mutants exhibit disorganized microtubule networks and inhibit neuronal process growth.2018
- Author(s)
  Watanabe N, Itakaoka M, Seki Y, Morimoto T, Homma K, Miyamoto Y, Yamauchi J
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 495 Issue: 1 Pages: 346-352
- DOI
  10.1016/j.bbrc.2017.11.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07127
[Journal Article] Pull down assay for GTP-bound form of Sar1a reveals its activation during morphological differentiation.2018
- Author(s)
  Urai Y, Yamawaki M, Watanabe N, Seki Y, Morimoto T, Tago K, Homma K, Sakagami H, Miyamoto Y, Yamauchi J
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 503 Issue: 3 Pages: 2047-2053
- DOI
  10.1016/j.bbrc.2018.07.157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17H03564
[Journal Article] Treacher Collins syndrome 3 (TCS3)-associated POLR1C mutants are localized in the lysosome and inhibits chondrogenic differentiation.2018
- Author(s)
  Matsumoto N, Kaneko M, Watanabe N, Itaoka M, Seki Y, Morimoto T, Torii T, Miyamoto Y, Keiichi Homma, Yamauchi J
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 499 Issue: 1 Pages: 78-85
- DOI
  10.1016/j.bbrc.2018.03.136
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Effects of HLD-associated POLR1C mutant proteins on cellular localization and differentiation.2018
- Author(s)
  Hiraoka Y, Hattori K, Takeuchi Y, Yamawaki M, Watanabe N, Matsumoto N, Homma K, Miyamoto Y, Yamauchi J
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 17 Pages: 80-82
- DOI
  10.1016/j.ymgmr.2018.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] The promoter region of 46-kDa CNPase is sufficient for its expression in corpus callosum.2018
- Author(s)
  Miyamoto Y, Torii T, Tanoue A, Yamamoto M, Yamauchi J
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 15 Pages: 78-79
- DOI
  10.1016/j.ymgmr.2018.03.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data on the effect of in vivo knockdown using artificial ErbB3 miRNA on Remak bundle structure.2017
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Kazuko Kawahara, Masashi Inoue, Takako Morimoto, Masahiro Yamamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 12 Pages: 313-319
- DOI
  10.1016/j.dib.2017.04.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data supporting the role of Fyn in embryonic sciatic nerve fasciculation.2017
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Kazuko Kawahara, Akito Tanoue, Yoichi Seki, Takako Morimoto, Masahiro Yamamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 11 Pages: 358-363
- DOI
  10.1016/j.dib.2017.02.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data on the effect of hypomyelinating leukodystrophy 6 (HLD6)-associated mutations on the TUBB4A properties.2017
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Kazuko Kawahara, Nanami Hasegawa, Akito Tanoue, Yoichi Seki, Takako Morimoto, Megumi Funakoshi-Tago, Hiroomi Tamura, Keiichi Homma, Masahiro Yamamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 11 Pages: 284-289
- DOI
  10.1016/j.dib.2017.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling.2017
- Author(s)
  Ruri Tsuneishi, Naoto Matsumoto, Misa Itaoka, Yuki Urai, Minami Kaneko, Natsumi Watanabe, Shou Takashima, Yoichi Seki, Takako Morimoto, Hiroyuki Sakagami, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 15 Pages: 234-239
- DOI
  10.1016/j.dib.2017.09.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-17H03564
[Journal Article] Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells.2017
- Author(s)
  Tomoko Yamashita, Yuki Miyamoto Yoshio Bando, Takashi Ono, Sakurako Kobayashi, Ayano Doi, Toshihiro Araki, Yosuke Kato, Takayuki Shirakawa, Yutaka Suzuki, Junji Yamauchi, Shigetaka Yoshida, and Naoya Sato
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 2 Pages: e0171947-e0171947
- DOI
  10.1371/journal.pone.0171947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127
[Journal Article] Defective myelination in mice harboring hypomyelinating leukodystrophy-associated HSPD1 mutation.2017
- Author(s)
  Yuki Miyamoto, Kazuko Kawahara, Tomohiro Torii, and Junji Yamauchi
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 11 Pages: 6-7
- DOI
  10.1016/j.ymgmr.2017.03.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127
[Journal Article] Neuregulin-1 type III knockout mice exhibit delayed migration of Schwann cell precursors.2017
- Author(s)
  Miyamoto Y, Torii T, Tanoue A, Kawahara K, Arai M, Tsumura H, Ogata T, Nagao M, Terada N, Yamamoto M, Takashima S, Yamauchi J
- Journal Title
  
  Biochemical and Biophysical Research Communication,
  
  Volume: 486 Issue: 2 Pages: 506-513
- DOI
  10.1016/j.bbrc.2017.03.074
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08463, KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data supporting mitochondrial morphological changes by spastic paraplegia (SPG) 13-associated HSPD1 mutants.2016
- Author(s)
  Yuki Miyamoto, Megumi Funakoshi-Tago, Nanami Hasegawa, Takahiro Eguchi, Akito Tanoue, Hiroomi Tamura, and Junji Yamauchi
- Journal Title
  
  Data Brief
  
  Volume: 6 Pages: 482-488
- DOI
  10.1016/j.dib.2015.12.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26830054
[Journal Article] Data supporting the role of Fyn in initiating myelination in the peripheral nervous system.2016
- Author(s)
  Yuki Miyamoto, Moe Tamano, Tomohiro Torii, Kazuko Kawahara, Kazuaki Nakamura, Akito Tanoue, Shuji Takada, and Junji Yamauchi
- Journal Title
  
  Data Breif
  
  Volume: 7 Pages: 1098-1105
- DOI
  10.1016/j.dib.2016.03.096
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054
[Journal Article] VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.2016
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 13478-13494
- DOI
  10.1038/ncomms13478
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054
[Journal Article] Social isolation impairs remyelination in mice through modulation of IL-6.2016
- Author(s)
  Makinodan M, Ikawa D, Miyamoto Y, Yamauchi J, Yamamuro K, Yamashita Y, Toritsuka M, Kimoto S, Okumura K, Yamauchi T, Fukami SI, Yoshino H, Wanaka A, Kishimoto T.
- Journal Title
  
  FASEB J.
  
  Volume: 30 Issue: 12 Pages: 4267-4274
- DOI
  10.1096/fj.201600537r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-16H06400, KAKENHI-PROJECT-26830054
[Journal Article] Arf6 mediates Schwann cell differentiation and myelination.2015
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Masahiro Yamamoto, Katsuya Ohbuchi, Hideki Tsumura, Kazuo Kawahara, Akito Tanoue, Hiroyuki Sakagami, and Jyunji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 465 Issue: 3 Pages: 450-457
- DOI
  10.1016/j.bbrc.2015.08.038
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054, KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-25290028
[Journal Article] Hypomyelinating leukodystrophy-associated missence mutation in HSPD1 blunts mitochondrial dynamics.2015
- Author(s)
  Yuki Miyamoto, Takahiro Eguchi, Kazuo Kawahara, Nanami Hasegawa, Kazuaki Nakamura, Megumi Funakoshi-Tago, Akito Tanoue, Hiroomi Tamura, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 462 Issue: 3 Pages: 275-281
- DOI
  10.1016/j.bbrc.2015.04.132
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-25460073, KAKENHI-PROJECT-25290028
[Journal Article] Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination.2015
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Shuji Takada, Nobuhiko Ohno, Yurika Saitoh, Kazuaki Nakamura, Akihito Ito, Toru Ogata, Nobuo Terada, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 26 Issue: 19 Pages: 3489-3503
- DOI
  10.1091/mbc.e14-05-1020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-25460267, KAKENHI-PROJECT-25290028, KAKENHI-PROJECT-26282159
[Journal Article] Arf6 guanine-nucleotide exchange factor cytohesin-2 regulates myelination in nerves.2015
- Author(s)
  Tomohiro Torii, Nobuhiko Ohno, Yuki Miyamoto, Kazuko Kawahara, Yurika Saitoh, Kazuaki Nakamura, Shou Takashima, Hiroyuki Sakagami, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 460 Issue: 3 Pages: 819-825
- DOI
  10.1016/j.bbrc.2015.03.113
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054, KAKENHI-PROJECT-15H04672
[Journal Article] Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination2014
- Author(s)
  Miyamoto Y, Yamamori N, Torii T, Tanoue A, Yamauchi J
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 25 Issue: 9 Pages: 1532-1542
- DOI
  10.1091/mbc.e13-10-0600
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25290028, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-26830054
[Journal Article] Arf6 guanine-nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth.2014
- Author(s)
  Torii T, Miyamoto Y, Tago K, Sango K, Nakamura K, Sanbe A, Tanoue A, Yamauchi J.
- Journal Title
  
  Journal of the Biological Chemistry
  
  Volume: 289 Issue: 49 Pages: 33887-33903
- DOI
  10.1074/jbc.m114.575787
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430056, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-26830054
[Journal Article] Hypomyelinating leukodystrophy-associated missense mutant of FAM126A/hyccin/DRCTNNB1A aggregates in the endoplasmic reticulum.2014
- Author(s)
  Yuki Miyamoto, Takahiro Eguchi, Tomohiro Torii, Kazuaki Nakamura, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  J. Clin. Neurosci.
  
  Volume: 21 Issue: 6 Pages: 1033-1039
- DOI
  10.1016/j.jocn.2013.09.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-26830054
[Journal Article] In vivo knockdown of ErbB3 in mice inhibits Schwann cell precursor migration.2014
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Shuji Takada, Hideki Tsumura, Miyuki Arai, Kazuaki Nakamura, Katsuya Ohbuchi, Masahiro Yamamoto, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 452 Issue: 3 Pages: 782-788
- DOI
  10.1016/j.bbrc.2014.08.156
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-26830054
[Journal Article] Dock6, a Dock-C subfamily guanine-nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth2007
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Atsushi Sanbe, Akito Tanoue
- Journal Title
  
  Exp. Cell Res. 313巻4号
  
  Pages: 791-804
- Data Source
  KAKENHI-PROJECT-18700375
[Journal Article] TrkB binds and tyrosine-phosphorylates Tiam1 leading to activation of Rac1 and induction of changes in cellular morphology2006
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Akito Tanoue, Chengbiao Wu, William C. Mobley
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103巻27号
  
  Pages: 10444-10449
- Data Source
  KAKENHI-PROJECT-18700375
[Journal Article] JNK phosphorylation of paxillin, acting through the Rac1 and Cdc42 signaling cascade, mediates neurite extension in N1E-115 cells2006
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Atsushi Sanbe, Akito Tanoue
- Journal Title
  
  Exp. Cell Res. 312巻15号
  
  Pages: 2954-2961
- Data Source
  KAKENHI-PROJECT-18700375
[Presentation] ペリツェウス・メルツ・バッヘル病モデルマウスに対する生薬Aの効果2024
- Author(s)
  山本未夢、宮本　幸、山内淳司
- Organizer
  日本ミエリン研究会
- Data Source
  KAKENHI-PROJECT-23K06821
[Presentation] エキソサイトーシス複合体はオリゴデンドロサイトの形態分化を制御する2023
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経化学会
- Data Source
  KAKENHI-PROJECT-23K06821
[Presentation] BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice.2019
- Author(s)
  宮本幸、山内淳司
- Organizer
  日本神経科学会・日本神経化学会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07127
[Presentation] 血管系にのみ発現するとされていた細胞接着因子による、新しい動的なミエリン（髄鞘）の形成メカニズム2018
- Author(s)
  宮本幸、山内淳司
- Organizer
  第41回　日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07127
[Presentation] VCAM1がオリゴデンドロサイトのミエリン形成を制御する2017
- Author(s)
  宮本幸、山内淳司
- Organizer
  日本ミエリン研究会
- Data Source
  KAKENHI-PROJECT-17K07127
[Presentation] VCAM1 regulates oligodendrocyte myelination2017
- Author(s)
  山内淳司、宮本幸
- Organizer
  日本神経化学会
- Data Source
  KAKENHI-PROJECT-17K07127
[Presentation] alpha1インテグリンリガンドとVCAM1受容体による中枢神経系ミエリン形成機構2017
- Author(s)
  宮本幸、山内淳司
- Organizer
  生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17K07127
[Presentation] Tyro3受容体とFynキナーゼは、ミエリン形成を司る新しいシグナル複合体を形成する2015
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本分子生物学会・日本生化学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26830054
[Presentation] Disease-assoiated modification of hereditary demyelinating disorder-related protein dynamics2015
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経化学会大会
- Place of Presentation
  大宮
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26830054
[Presentation] ErbB3 is required for Schwann cell precursor migration2015
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経科学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-29
- Data Source
  KAKENHI-PROJECT-26830054
[Presentation] Derivation of oligodendrocytes from human iPS cells and monkey ES cells maintained in a single-cell and feeder-free culture2015
- Author(s)
  山下智子、土井綾乃、小林桜子、小野貴史、鈴木　豊、荒木利博、青木久範、佐藤直也、宮本　幸、山内淳司、板東良雄、吉田成孝
- Organizer
  日本神経科学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-29
- Data Source
  KAKENHI-PROJECT-26830054
[Presentation] 末梢神経の発生・再生過程を制御するDock6による新規メカニズム2014
- Author(s)
  宮本　幸、鳥居知宏、田上昭人、山内淳司
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-26830054
[Presentation] 中枢神経脱随疾患HLD5変異による以上FAM126A蛋白質は脳梁で凝集し脱随を誘導する可能性がある2014
- Author(s)
  宮本　幸、鳥居知宏、田上昭人、山内淳司
- Organizer
  日本神経化学会
- Place of Presentation
  奈良県文化会館
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-26830054

1. KAWAHARA Kazuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. MAKINODAN Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. TERADA Nobuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 山内淳司

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
5. 吉岡望

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 三五一憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 阪上洋行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIYAMOTO Yuki 宮本 幸

宮本 幸 ミヤモト ユキ

Miyamoto Yuki 宮本 幸

Research Projects

Research Products

Co-Researchers

Elucidation of the pathophysiological mechanism of demyelinating neuropathies using a novel co-culture modelPrincipal Investigator

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Elucidation of the molecular network that controls myelinationPrincipal Investigator

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FROM THE QUESTION OF HOW GLIAL CELLS WRAP THEIR MEMBRANE WITH AXONS TO THE POSSIBLE SOLUTION OF HOW DEMYELINATING DISORDERS WERE RECOVEREDPrincipal Investigator

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末梢神経の初期発生過程とその病態形成のシグナル伝達Principal Investigator

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[Journal Article] Autism spectrum disorder-and/or intellectual disability-associated Semaphorin-5A exploits the mechanism by which Dock5 signalsome molecules control cell shape.2024

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[Journal Article] Rab11a controls cell shape via C9orf72 protein: possible relationships to frontotemporal dementia/amyotrophic lateral scleorosis (FTDALS) type 1.2024

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[Journal Article] Modulating Golgi stress signaling ameliorates cell morphological phenotypes induced by CHMP2B with frontotemporal dementia-associated p.Asp148Tyr.2024

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[Journal Article] Lethal Adulthood Myelin Breakdown by Oligodendrocyte-specific Ddx54 Knockout2023

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[Journal Article] FTD/ALS type7-associated Thr104Asn mutation of CHMP2B blunts neuronal process elongation, and is recovered by knockdown of Arf4, the Golgi stress regulator.2023

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[Journal Article] Defective oligodendrocyte differentiation by hypomyelinating leukodystrophy 13 (HLD13)-associated mutation of Hikeshi.2023

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[Journal Article] Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.2023

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[Journal Article] Knockdown of Rab7B, but not of Rab7A, which antagonistically regulates oligodendroglial cell morphological differentiation, recovers tunicamycin-induced defective differentiation in FBD-102b cells.2023

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[Journal Article] Investigating the protective effects of a citrus flavonoid on the retardation morphogenesis of the oligodendroglia-like cell line by Rnd2 knockdown.2023

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[Journal Article] RhoG-binding domain of Elmo1 ameliorates excessive process elongation induced by autism spectrum disorder-associated Sema5A.2023

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MIYAMOTO Yuki 宮本幸

宮本幸ミヤモトユキ

Miyamoto Yuki 宮本幸