Sugimoto Masataka 杉本昌隆

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SUGIMOTO Masataka 杉本昌隆

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Researcher Number	50426491
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立長寿医療研究センター, 研究所ジェロサイエンス研究センター, 部長
Affiliation (based on the past Project Information) *help	2021 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究副部長 2020: 国立研究開発法人国立長寿医療研究センター, ジェロサイエンス研究センター, 副部長 2017 – 2018: 国立研究開発法人国立長寿医療研究センター, 老化機構研究部, 室長 2016: 国立研究開発法人国立長寿医療研究センター, 老化機構研究部, 免疫研究室長 2015: 国立長寿医療研究センター, 老化機構研究部, 室長 … More 2013 – 2014: 独立行政法人国立長寿医療研究センター, 老化細胞研究プロジェクトチーム, プロジェクトリーダー 2012: 国立長寿医療センター, 研究所, プロジェクトリーダー 2012: 独立行政法人国立長寿医療研究センター, その他部局等, その他 2011: 独立行政法人国立長寿医療研究センター, 老化細胞研究プロジェクトチーム, プロジェクトリーダー 2010 – 2011: 独立行政法人国立長寿医療研究センター, 老化細胞プロジェクトチーム, プロジェクトリーダー 2010: 国立長寿医療センター(研究所), 老化機構研究部, 室長 2007 – 2008: National Institute for Longevity Sciences,NCGG, 老化機構研究部・代謝研究室, 室長 2006: 国立長寿医療センター, (研究所)・老化機構研究部, 室長 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / General medical chemistry / Metabolomics / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields Except Principal Investigator Pathological medical chemistry / Pediatrics
Keywords	Principal Investigator 細胞老化 / COPD / 呼吸器 / 肺気腫 / セノリシス / モデル動物 / 呼吸器疾患 / 翻訳 / RNA結合タンパク質 / 脂肪細胞 … More / 再生 / 運動 / マイオカイン / 運動モデル / senolysis / 肺がん / COPD（肺気腫） / 転移性肺がん / 癌抑制タンパク質 / モデルマウス / Senolytic薬 / 肺 / 老化 / ARF / 翻訳制御 / SASP / HuR / インスリン抵抗性 / 転写因子 / mRNA翻訳 / 代謝異常学 … More Except Principal Investigator インビボイメージングシステム / 白色脂肪組織 / ２型糖尿病 / メタボリックシンドローム / 分子病態学 / トランスジェニックマウス / 生体イメージングシステム / 2型糖尿病 / 細胞老化 / T細胞受容体 / C/EBPα / ATM / 神経幹細胞 / iPS細胞 / microRNA / 脂肪細胞 / 毛細血管拡張性運動失調症 / 細胞分化 / ＡＴＭ / 急性リンパ性白血病 / PARP阻害剤 / 小児腫瘍学 Less

組織再生と加齢に伴う呼吸器機能変化の関連解析と治療戦略の展開Principal Investigator
- Principal Investigator
  
  杉本昌隆
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
運動による老化細胞除去機構の解明ー慢性呼吸器疾患治療モデルへの展開Principal Investigator
- Principal Investigator
  
  杉本昌隆
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Pathophysiological roles of cellular senescence in lung aging and diseasesPrincipal Investigator
- Principal Investigator
  
  Sugimoto Masataka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  National Center for Geriatrics and Gerontology
Roloes of cellular senescence in pulmonary diseasePrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Masataka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  National Center for Geriatrics and Gerontology
Potential for the therapy of type 2 diabates by removal of senescent cells from adipose tissue
- Principal Investigator
  
  HASHIMOTO Michihiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chubu University
  National Center for Geriatrics and Gerontology
Role of post-transcriptional regulation in cellular senescencePrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Masataka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  National Center for Geriatrics and Gerontology
Analysis of cell differentiation machinery regulated by ATM
- Principal Investigator
  
  PIAO Jinhua
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Medical and Dental University
R oleofadipocyte-pcificmRNAregulatorysysteminthecontrol ofinsulin-mediatedglesucosemetabolismPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Masataka
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  National Center for Geriatrics and Gerontology
Role of HZF in adipocyte differentiationPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Masataka
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Metabolomics
- Research Institution
  National Institute for Longevity Sciences,NCGG

[Journal Article] 老化と肺疾患2024
- Author(s)
  廣瀬美嘉子、津島博道、杉本昌隆
- Journal Title
  
  日本臨牀
  
  Volume: 82 Pages: 66-71
- Data Source
  KAKENHI-PROJECT-22K19743
[Journal Article] 老化と肺疾患2024
- Author(s)
  廣瀬美嘉子、津島博道、杉本昌隆
- Journal Title
  
  日本臨牀
  
  Volume: 82 Pages: 66-71
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] Age-related changes in lung function in National Center for Geriatrics and Gerontology Aging Farm C57BL/6N mice2023
- Author(s)
  Kawaguchi Koichiro、Asai Azusa、Mikawa Ryuta、Ogiso Noboru、Sugimoto Masataka
- Journal Title
  
  Exp. Anim.
  
  Volume: 72 Issue: 2 Pages: 173-182
- DOI
  10.1538/expanim.22-0109
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19743, KAKENHI-PROJECT-20H04116
[Journal Article] 肺組織における細胞老化2023
- Author(s)
  津島博道、杉本昌隆
- Journal Title
  
  医学のあゆみ
  
  Volume: 284 Pages: 363-366
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] 肺組織における細胞老化2023
- Author(s)
  津島博道、杉本昌隆
- Journal Title
  
  医学のあゆみ
  
  Volume: 284 Pages: 363-366
- Data Source
  KAKENHI-PROJECT-22K19743
[Journal Article] Senolysisと呼吸器疾患2023
- Author(s)
  津島博道、杉本昌隆
- Journal Title
  
  炎症と免疫
  
  Volume: 31 Pages: 8-13
- Data Source
  KAKENHI-PROJECT-22K19743
[Journal Article] Targeting cellular senescence: A promising approach in respiratory diseases2023
- Author(s)
  Sugimoto Masataka
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 24 Issue: S1 Pages: 60-66
- DOI
  10.1111/ggi.14653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19743, KAKENHI-PROJECT-20H04116
[Journal Article] 細胞老化とフレイル2022
- Author(s)
  津島博道、細山　徹、杉本昌隆
- Journal Title
  
  日本サルコペニア・フレイル学会誌
  
  Volume: 6 Pages: 5-9
- Data Source
  KAKENHI-PROJECT-22K19743
[Journal Article] 呼吸器疾患における細胞老化の病理的役割2022
- Author(s)
  杉本昌隆、川口耕一郎
- Journal Title
  
  実験医学
  
  Volume: 39 Pages: 390-394
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] 細胞老化とフレイル2022
- Author(s)
  津島博道、細山　徹、杉本昌隆
- Journal Title
  
  日本サルコペニア・フレイル学会誌
  
  Volume: 6 Pages: 5-9
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] Cellular senescence promotes cancer metastasis by enhancing soluble E-cadherin production2021
- Author(s)
  Kawaguchi Koichiro、Komoda Kaori、Mikawa Ryuta、Asai Azusa、Sugimoto Masataka
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 9 Pages: 103022-103022
- DOI
  10.1016/j.isci.2021.103022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20172, KAKENHI-PROJECT-20H04116
[Journal Article] Protocol for assessing the senescence-associated lung pathologies2021
- Author(s)
  Kawaguchi K, Hashimoto M, Mikawa R, Asai A, Sato T, Sugimoto M.
- Journal Title
  
  STAR Protoc
  
  Volume: 2 Issue: 4 Pages: 100993-100993
- DOI
  10.1016/j.xpro.2021.100993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08575, KAKENHI-PROJECT-19K20172, KAKENHI-PROJECT-20H04116
[Journal Article] An antioxidant suppressed lung cellular senescence and enhanced pulmonary function in aged mice2021
- Author(s)
  Kawaguchi Koichiro、Hashimoto Michihiro、Sugimoto Masataka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 541 Pages: 43-49
- DOI
  10.1016/j.bbrc.2020.12.112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20172, KAKENHI-PROJECT-20H04116
[Journal Article] Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders2021
- Author(s)
  Johmura Yoshikazu、Yamanaka Takehiro、Omori Satotaka、Wang Teh-Wei、Sugiura Yuki、Matsumoto Masaki、Suzuki Narumi、Kumamoto Soichiro、Yamaguchi Kiyoshi、Hatakeyama Seira、Takami Tomoyo、Yamaguchi Rui、Shimizu Eigo、Ikeda Kazutaka、Okahashi Nobuyuki、Mikawa Ryuta、Suematsu Makoto、Arita Makoto、Sugimoto Masataka et al
- Journal Title
  
  Science
  
  Volume: 371 Issue: 6526 Pages: 265-270
- DOI
  10.1126/science.abb5916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H04116
[Journal Article] Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice2021
- Author(s)
  Suda M、Shimizu I、Katsuumi G、Yoshida Y、Hayashi Y、Ikegami R、Matsumoto N、Yoshida Y、Mikawa R、Katayama A、Wada J、Seki M、Suzuki Y、Iwama A、Nakagami H、Nagasawa A、Morishita R、Sugimoto M、Okuda S、Tsuchida M、Ozaki K、Nakanishi-Matsui M、Minamino T
- Journal Title
  
  Nature Aging
  
  Volume: 1 Issue: 12 Pages: 1117-1126
- DOI
  10.1038/s43587-021-00151-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06646, KAKENHI-PROJECT-20H04116, KAKENHI-PROJECT-23K21360
[Journal Article] SASPによる疾病発症メカニズム2021
- Author(s)
  川口耕一郎、杉本昌隆
- Journal Title
  
  医学のあゆみ
  
  Volume: 279 Pages: 374-377
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] Effects of CREG1 on age-associated metabolic phenotypes and renal senescence in mice2021
- Author(s)
  Hashimoto M, Goto A, Endo Y, Sugimoto M, Ueda J, and Yamashita H
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 3 Pages: 1276-1276
- DOI
  10.3390/ijms22031276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06450, KAKENHI-PROJECT-18K11034, KAKENHI-PROJECT-18K17934, KAKENHI-PROJECT-20H04116, KAKENHI-PROJECT-19K06452
[Journal Article] Lamivudine Inhibits Alu RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities2020
- Author(s)
  Yamada K, Kaneko H*, Shimizu H, Suzumura A, Namba R, Takayama K, Ito S, Sugimoto M, Terasaki H.
- Journal Title
  
  Transl Vis Sci Technol.
  
  Volume: 9 Issue: 8 Pages: 1-1
- DOI
  10.1167/tvst.9.8.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09988, KAKENHI-PROJECT-20H04116
[Journal Article] 細胞老化2020
- Author(s)
  川口耕一郎、三河隆太、杉本昌隆
- Journal Title
  
  医学のあゆみ
  
  Volume: 273 Pages: 332-337
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] 呼吸器の老化・疾患と細胞老化2020
- Author(s)
  川口耕一郎、杉本昌隆
- Journal Title
  
  基礎老化研究
  
  Volume: 44-3 Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] Caveolin-1 Promotes Cellular Senescence in Exchange for Blocking Subretinal Fibrosis in Age-Related Macular Degeneration2020
- Author(s)
  Shimizu H, Yamada K, Suzumura A, Kataoka K, Takayama K, Sugimoto M, Terasaki H, Kaneko H
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 61 Issue: 11 Pages: 21-21
- DOI
  10.1167/iovs.61.11.21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09988, KAKENHI-PROJECT-19K09989, KAKENHI-PROJECT-20H04116
[Journal Article] 肺疾患における細胞老化の役割2020
- Author(s)
  川口耕一郎、杉本昌隆
- Journal Title
  
  老年内科
  
  Volume: 2 Pages: 552-559
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] 老化細胞の除去(senolysis)による加齢性疾患治療へのアプローチ2020
- Author(s)
  杉本昌隆、川口耕一郎
- Journal Title
  
  Farumashia
  
  Volume: 56 Issue: 11 Pages: 1009-1013
- DOI
  10.14894/faruawpsj.56.11_1009
- NAID
  130007933981
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-20H04116
[Journal Article] Elimination of p19ARF-expressing cells protects against pulmonary emphysema in mice2018
- Author(s)
  Mikawa R, Suzuki Y, Baskoro H, Kanayama K, Sugimoto K, Sato T, Sugimoto M
- Journal Title
  
  Aging Cell
  
  Volume: 17 Issue: 5
- DOI
  10.1111/acel.12827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09668, KAKENHI-PROJECT-16K08604
[Journal Article] Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice2017
- Author(s)
  Suzuki Yohei、Sato Tadashi、Sugimoto Masataka、Baskoro Hario、Karasutani Keiko、Mitsui Aki、Nurwidya Fariz、Arano Naoko、Kodama Yuzo、Hirano Shin-ichi、Ishigami Akihito、Seyama Kuniaki、Takahashi Kazuhisa
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 492 Issue: 1 Pages: 74-81
- DOI
  10.1016/j.bbrc.2017.08.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08604, KAKENHI-PROJECT-17K09668, KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-26461199
[Journal Article] Elimination of p19ARF-expressing cells enhances pulmonary function in mice.2016
- Author(s)
  1.Hashimoto M., Asai A., Kawagishi H., Mikawa R., Iwashita Y., Kanayama K., Sugimoto K., Sato T., Maruyama M., and Sugimoto M.
- Journal Title
  
  JCI insight
  
  Volume: 1 Issue: 12
- DOI
  10.1172/jci.insight.87732
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08604, KAKENHI-PROJECT-26461199
[Journal Article] ATM regulates adipocyte differentiation and contributes to glucose homeostasis.2015
- Author(s)
  Takagi M., Uno M., Nishii R., Sugimoto M., Hasegawa S., Piao J., Ihara N., Kanai S., Kakei S., Tamura Y., Suganami T., Kamei Y., Shimizu T., Yasuda A., Ogawa Y., Mizutani S.
- Journal Title
  
  Cell Reports
  
  Volume: 10 Issue: 6 Pages: 957-967
- DOI
  10.1016/j.celrep.2015.01.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590368, KAKENHI-PROJECT-26670515, KAKENHI-PROJECT-15K12669, KAKENHI-PROJECT-25292076
[Journal Article] Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB.2014
- Author(s)
  Hashimoto M, Tsugawa T, Kawagishi H, Asai A, Sugimoto M.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1840 Issue: 10 Pages: 3079-3087
- DOI
  10.1016/j.bbagen.2014.07.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590368
[Journal Article] Artemis-dependent DNA double-strand break formation at stalled replication forks.2013
- Author(s)
  Unno J, Takagi M, Piao J, Sugimoto M, Honda F, Maeda D, Masutani M, Kiyono T, Watanabe F, Morio T, Teraoka H, Mizutani S.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 6 Pages: 703-10
- DOI
  10.1111/cas.12144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390270, KAKENHI-PROJECT-23390271, KAKENHI-PROJECT-24590368
[Journal Article] HuR maintains replicative lifespan by suppressing ARF tumor suppressor.2013
- Author(s)
  Kawagishi, H., Hashimoto, M., Nakamura, H., Tsugawa, T., Watanabe, A., Kontoyiannis, D. L., and Sugimoto, M.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 33 Issue: 10 Pages: 1886-1900
- DOI
  10.1128/mcb.01277-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590368
[Journal Article] Autoimmunity and persistent RAS- mutated clones long after the spontaneous regression of JMML2013
- Author(s)
  Takagi M, Imai C, et al
- Journal Title
  
  Leukemia
  
  Volume: 27 Issue: 9 Pages: 1926-1928
- DOI
  10.1038/leu.2013.82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591349, KAKENHI-PROJECT-23591552, KAKENHI-PROJECT-24590368, KAKENHI-PROJECT-25461581
[Journal Article] Cooperative role of the RNA-binding proteins Hzf and HuR in p53 activation2011
- Author(s)
  Nakamura H,Kawagishi H,Watanabe A, Sugimoto K, Maruyama M, Sugimoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Issue: 10 Pages: 101997-2009
- DOI
  10.1128/mcb.01424-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591121, KAKENHI-PROJECT-22790879
[Journal Article] Hzf regulates adipogenesis through translational control of C/EBPα2008
- Author(s)
  Hiroyuki Kawagishi, Takeshi Wakoh, Hatsume Uno, Mitsuo Maruyama, Ayako Moriya, Satoru Morikawa, Hideyuki Okano, Charles J. Sherr, Masatoshi Takagi, Masataka Sugimoto
- Journal Title
  
  The EMBO Journal 27(10)
  
  Pages: 1481-1490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689021
[Journal Article] Hzf, a p53-responsive gene, regulates maintenance of the G2 phase checkpoint induced by DNA damage.2006
- Author(s)
  Masataka Sugimoto
- Journal Title
  
  Molecular and Cellular Biology 26・2
  
  Pages: 502-502
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Senescent Cells and Emphysema: A Path to Lung Recovery2024
- Author(s)
  Masataka Sugimoto
- Organizer
  JSPS A3 Foresight Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Senescent Cells and Emphysema: A Path to Lung Recovery2024
- Author(s)
  Masataka Sugimoto
- Organizer
  JSPS A3 Foresight Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] マウス骨格筋由来抗細胞老化因子（seno-suppressor）の解析2023
- Author(s)
  津島博道、浅井あづさ、細山　徹、多田敬典、杉本昌隆
- Organizer
  第33回日本老年学会
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 呼吸器疾患における老化細胞の病理的役割：セノセラピーモデルの確立へ2023
- Author(s)
  杉本昌隆
- Organizer
  第23回日本抗加齢医学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] 筋由来Seno-suppressorの機能および運動モデルにおける動態解析2023
- Author(s)
  津島博道、浅井あずさ、細山　徹、多田敬典、杉本昌隆
- Organizer
  第23回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Pathophysiological roles of cellular senescence in pulmonary aging and diseases.2023
- Author(s)
  Masataka Sugimoto
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Pathophysiological roles of cellular senescence in pulmonary aging and diseases.2023
- Author(s)
  Masataka Sugimoto
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] 肺組織の老化・疾患と細胞老化2023
- Author(s)
  杉本昌隆
- Organizer
  第67 回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] 呼吸器疾患における細胞老化の病理的役割と老化細胞を標的とした治療モデルの確立2023
- Author(s)
  杉本昌隆
- Organizer
  第33回日本老年学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 肺組織の老化・疾患と細胞老化2023
- Author(s)
  杉本昌隆
- Organizer
  第67 回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 肺組織の老化・疾患における細胞老化の役割2023
- Author(s)
  杉本昌隆
- Organizer
  第45回心筋生検研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] マウス骨格筋由来抗細胞老化因子（seno-suppressor）の解析2023
- Author(s)
  津島博道、浅井あづさ、細山　徹、多田敬典、杉本昌隆
- Organizer
  第33回日本老年学会
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] 呼吸器疾患における細胞老化の病理的役割と老化細胞を標的とした治療モデルの確立2023
- Author(s)
  杉本昌隆
- Organizer
  第33回日本老年学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] 呼吸器疾患における老化細胞の病理的役割：セノセラピーモデルの確立へ2023
- Author(s)
  杉本昌隆
- Organizer
  第23回日本抗加齢医学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 肺組織の老化・疾患における細胞老化の役割2023
- Author(s)
  杉本昌隆
- Organizer
  第45回心筋生検研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 筋由来Seno-suppressorの機能および運動モデルにおける動態解析2023
- Author(s)
  津島博道、浅井あずさ、細山　徹、多田敬典、杉本昌隆
- Organizer
  第23回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] Senolysis enhances alveolar regeneration and ameliorates emphysema-associated pathologies.2022
- Author(s)
  杉本昌隆
- Organizer
  23rd Northeastern Asian Symposium on Cellular Senescence: From Physiology to Treatment
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] マウス筋細胞由来抗細胞老化因子の探索2022
- Author(s)
  津島博道、浅井あづさ、細山　徹、多田敬典、杉本昌隆
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] Senolysis enhances alveolar regeneration and ameliorates emphysema-associated pathologies2022
- Author(s)
  杉本昌隆
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 細胞老化・疾患における細胞老化の役割―Cellular senescence：a potential therapeutic target―2022
- Author(s)
  杉本昌隆
- Organizer
  第35回日本酸化ストレス学会関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] Senolysis enhances alveolar regeneration and ameliorates emphysema-associated pathologies.2022
- Author(s)
  杉本昌隆
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-22K19743
[Presentation] 細胞老化・疾患における細胞老化の役割―Cellular senescence：a potential therapeutic target―2022
- Author(s)
  杉本昌隆
- Organizer
  第35回日本酸化ストレス学会関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] マウス筋細胞由来抗細胞老化因子の探索2022
- Author(s)
  津島博道、浅井あづさ、細山　徹、多田敬典、杉本昌隆
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Senolysis enhances alveolar regeneration and ameliorates emphysema-associated pathologies.2022
- Author(s)
  Masataka Sugimoto
- Organizer
  23rd Northeastern Asian Symposium on Cellular Senescence: From Physiology to Treatment
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Senescence-dependent alveolar factor promotes cancer metastasis.2021
- Author(s)
  Koichiro Kawaguchi, Kaori Komoda, Ryuta Mikawa, Azusa Asai, Masataka Sugimoto
- Organizer
  第44回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Senolysis: a potential approach against pulmonary aging and diseases.2021
- Author(s)
  Masataka Sugimoto
- Organizer
  第80回日本癌学会学術総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Senescence-dependent ectodomain shedding of E-cadherin promotes cancer metastasis.2021
- Author(s)
  Koichiro Kawaguchi, Azusa Asai, Masataka Sugimoto
- Organizer
  The 6th International Cell Senescence Association Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 呼吸器疾患における細胞老化の役割2021
- Author(s)
  杉本昌隆
- Organizer
  日本再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 呼吸器疾患における細胞老化の役割2021
- Author(s)
  杉本昌隆
- Organizer
  第21回抗加齢医学会総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Senescence-dependent alveolar factor promotes metastatic lung cancer.2020
- Author(s)
  Kawaguchi K, Sugimoto M.
- Organizer
  Mechanism of Aging, Cold Spring Harbor Laboratory Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] Alveolar senescene promotes lung metastasis of melanoma cells.2020
- Author(s)
  川口耕一郎、古茂田かおり、三河隆太、浅井あづさ、杉本昌隆
- Organizer
  日本基礎老化学会
- Data Source
  KAKENHI-PROJECT-20H04116
[Presentation] 肺組織の老化と細胞老化2019
- Author(s)
  杉本昌隆
- Organizer
  第18回日本再生医療学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] Pathophysiological roles of cellular senescence in pulmonary diseases.2018
- Author(s)
  Masataka Sugimoto
- Organizer
  The 4th ICAH-NCGG symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] Cellular senescence in pulmonary aging and disease.2018
- Author(s)
  Masataka Sugimoto
- Organizer
  第77回日本癌学会学術総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] The therapeutic and preventive potential of targeting senescent cells in pulmonary emphysema. Mechanism of Aging,2018
- Author(s)
  Ryuta Mikawa, Masataka Sugimoto
- Organizer
  Mechanism of Aging, Cold Spring Harbor Laboratory Meeting,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] 肺気腫における老化細胞を標的とした治療と予防の可能性2018
- Author(s)
  三河隆太、杉本昌隆
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] 呼吸器の老化・疾患における細胞老化の役割2018
- Author(s)
  杉本昌隆
- Organizer
  第60回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] Clearance of senescent cells ameliorates emphysema-associated pathologies in mice2017
- Author(s)
  三河隆太、鈴木洋平、丸山光生、佐藤　匡、杉本昌隆
- Organizer
  第30回日本老年学会総会
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] Roles of cellular senescence in pulmonary aging and disease.2017
- Author(s)
  杉本昌隆
- Organizer
  第49回日本結合組織学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] 組織老化・疾患における細胞老化の役割2017
- Author(s)
  杉本昌隆
- Organizer
  第3回川島カンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] 細胞老化の除去による肺気腫病変の抑制2017
- Author(s)
  三河隆太、杉本昌隆
- Organizer
  ConBio 2017
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] Pathophysiological roles of p19ARF in pulmonary aging.2016
- Author(s)
  Sugimoto M
- Organizer
  第39回日本分子生物学会年会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] 呼吸器の加齢性変化における癌抑制タンパク質ARFの役割2016
- Author(s)
  杉本昌隆
- Organizer
  第9回Symphony
- Place of Presentation
  東京
- Year and Date
  2016-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] Pathophysiological roles of cellular senescence in lung aging.2016
- Author(s)
  Sugimoto M
- Organizer
  NCGG-ICAH symposium
- Place of Presentation
  台北
- Year and Date
  2016-04-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08604
[Presentation] HuR maintains replicative lifespan by repressing ARF tumor suppressor.2012
- Author(s)
  Sugimoto,M, Kawagishi,H., Tsugawa,T., and Hashimoto,M.
- Organizer
  Keystone Symposia Aging and Diseases of Aging
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-24590368
[Presentation] HuR regulates senescence-associated secretory phenotype through DNA damage response pathway.2012
- Author(s)
  Tsugawa,T, Michihiro,H., Kawagishi,H, and Sugimoto,M.
- Organizer
  第35回大会　日本分子生物学会年会（ワークショップ）
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590368
[Presentation] RNA結合タンパク質HuRは癌抑制タンパク質ARFを抑制することにより細胞の分裂寿命を維持する2012
- Author(s)
  杉本昌隆、川岸裕幸、津川貴行、中村英亮
- Organizer
  日本基礎老化学会第35回大会
- Place of Presentation
  東邦大学
- Data Source
  KAKENHI-PROJECT-24590368
[Presentation] RNA-binding protein HuR suppressescellular lifespan by repressing the translation of ARF mRNA2011
- Author(s)
  Kawagishi, H. and Sugimoto, M
- Organizer
  Mechanism and Model of Cancer, SALK symposia
- Year and Date
  2011-08-17
- Data Source
  KAKENHI-PROJECT-22790879
[Presentation] HuR maintains replicative lifespan by repressing ARF tumor suppressor2011
- Author(s)
  Kawagishi, H., Nakamura, H., Tsugawa, T. and Sugimoto, M
- Organizer
  第34回大会日本分子生物学会年会横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790879
[Presentation] Post-transcriptional regulation of the p53 pathway2010
- Author(s)
  杉本昌隆
- Organizer
  基礎老化学会シンポジウム
- Place of Presentation
  名古屋大学
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22790879
[Presentation] Post-transcriptionalregulation of the p53 pathway2010
- Author(s)
  Sugimoto, M
- Organizer
  日本基礎老化学会第33回大会シンポジウム愛知県
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22790879
[Presentation] Post-transcriptional regulation of the p53 tumor suppressor2010
- Author(s)
  Nakamura, H., Kawagishi, H., Watanabe, A, Maruyama, M., Sugimoto, M
- Organizer
  Molecular Genetics of Aging, Cold Spring Harbor Laboratory Meeting
- Year and Date
  2010-08-18
- Data Source
  KAKENHI-PROJECT-22790879
[Presentation] Hzf collaborates with HuR to regulate adipogenesis2008
- Author(s)
  杉本昌隆
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Hzf collaborates with HuR to regulate adipogenesis2008
- Author(s)
  Masataka Sugimoto
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Role of Hzf in adipocyte differentiation2008
- Author(s)
  杉本昌隆
- Organizer
  第一回FANTASY
- Place of Presentation
  東京
- Year and Date
  2008-02-02
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Role of Hzf in adipocyte differentiation2008
- Author(s)
  杉本昌隆
- Organizer
  第一回FANTASY
- Place of Presentation
  グランドパレス(東京)
- Year and Date
  2008-02-02
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Hzf regulates the translation of C/EBPalpha during adipocyte differentiation2007
- Author(s)
  杉本昌隆
- Organizer
  BMB2007
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Hzf regulates the translation of C/EBPalpha during adipocyte differentiation2007
- Author(s)
  杉本昌隆
- Organizer
  The 7th MBSJ Spring Symposium
- Place of Presentation
  淡路舞台国際会議場
- Year and Date
  2007-04-23
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Hzf regulates the translation of CEBPalpha mRNA during adipocyte differentiation2007
- Author(s)
  Masataka Sugimoto
- Organizer
  The 7th MBSJ Spring Symposium
- Place of Presentation
  兵庫
- Year and Date
  2007-04-23
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Hzf regulates the translation of C/EBPalpha mRNA during adipocyte differentiation2007
- Author(s)
  Masataka Sugimoto
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] Role of Hzf in adipocyte differentiation2006
- Author(s)
  Masataka Sugimoto
- Organizer
  The 11th Adiposcience Symposium
- Place of Presentation
  大阪
- Year and Date
  2006-08-19
- Data Source
  KAKENHI-PROJECT-18689021
[Presentation] 転写後発現調節機構を介した細胞老化の制御
- Author(s)
  橋本理尋、川岸裕幸、杉本昌隆
- Organizer
  日本基礎老化学会第35回大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590368
[Presentation] Regulation of senescence-associated phenotypes by RNA-binding protein HuR.
- Author(s)
  Tusugawa,T., Hashimoto,M., Kawagishi,H., and Sugimoto,M.
- Organizer
  Salk Symposia Mechanisms and Models of Cancer
- Place of Presentation
  La Jolla (米国)
- Data Source
  KAKENHI-PROJECT-24590368
[Presentation] 転写後発現調節機構を介した細胞老化の制御
- Author(s)
  杉本昌隆
- Organizer
  第65回日本細胞生物学会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24590368

1. 佐藤匡 (10596993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 杉本和史 (60378370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 42 results
3. PIAO Jinhua (70567750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKAGI Masatoshi (10406267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HASHIMOTO Michihiro (90724253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 村上太郎 (10252305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 多田敬典 (20464993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 細山徹 (20638803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 渡邉淳 (90321843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 橋本真一 (00313099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KANAYAMA Kazuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. YAMAGUCHI Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. NAKANISHI Mayumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. GOTO Naomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. IMAI Chihaya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 森尾友宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 兼子裕規

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 川口耕一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 山下均

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 後藤亜由美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugimoto Masataka 杉本 昌隆

SUGIMOTO Masataka 杉本 昌隆

Research Projects

Research Products

Co-Researchers

組織再生と加齢に伴う呼吸器機能変化の関連解析と治療戦略の展開Principal Investigator

Principal Investigator

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運動による老化細胞除去機構の解明ー慢性呼吸器疾患治療モデルへの展開Principal Investigator

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Pathophysiological roles of cellular senescence in lung aging and diseasesPrincipal Investigator

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Roloes of cellular senescence in pulmonary diseasePrincipal Investigator

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Potential for the therapy of type 2 diabates by removal of senescent cells from adipose tissue

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Role of post-transcriptional regulation in cellular senescencePrincipal Investigator

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Analysis of cell differentiation machinery regulated by ATM

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R oleofadipocyte-pcificmRNAregulatorysysteminthecontrol ofinsulin-mediatedglesucosemetabolismPrincipal Investigator

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Role of HZF in adipocyte differentiationPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] 老化と肺疾患2024

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[Journal Article] 老化と肺疾患2024

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[Journal Article] Age-related changes in lung function in National Center for Geriatrics and Gerontology Aging Farm C57BL/6N mice2023

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[Journal Article] 肺組織における細胞老化2023

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[Journal Article] 肺組織における細胞老化2023

Author(s)

Sugimoto Masataka 杉本昌隆

SUGIMOTO Masataka 杉本昌隆