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KONISHI Tetsuro  小西 哲郎

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… Alternative Names

小西 哲郎  コニシ テツロウ

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Researcher Number 50426508
Affiliation (Current) 2025: 独立行政法人国立病院機構(宇多野病院臨床研究部), その他部局等, 研究員(移行)
Affiliation (based on the past Project Information) *help 2014: 独立行政法人国立病院機構宇多野病院, 神経内科, 院長
2011: 独立行政法人国立病院機構宇多野病院, 神経内科, 院長
Review Section/Research Field
Except Principal Investigator
Neurology
Keywords
Except Principal Investigator
疾患モデル / MuSK / 重症筋無力症 / IgG4 / プロテアソーム / Th2 / 3,4-DAP / ラパマイシン / 疾患モデル動物 / muscle-specifc kinase … More / LRP4 / 自己抗体 / 神経筋シナプス / 重病筋無力症 / muscle-specific kians / 治療薬 / 動物疾患モデル / 神経筋接合部 Less
  • Research Projects

    (2 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (7 People)
  •  Elucidation of pathogenic mechanisms and developing new therapies of myasthenia gravis

    • Principal Investigator
      SHIGEMOTO KAZUHIRO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Elucidation of pathogenic mechanisms of myasthenia gravis caused by MuSK antibodies using a new synchronized experimental animal model

    • Principal Investigator
      SHIGEMOTO Kazuhiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

All 2014 2013 2012

All Journal Article Presentation

  • [Journal Article] 動物モデルによる重症筋無力症の病態機序の解明2014

    • Author(s)
      森 秀一, 高嶋 留美, 小西 哲郎, 重本 和宏
    • Journal Title

      神経内科

      Volume: 80 Pages: 475-483

    • Data Source
      KAKENHI-PROJECT-24390228
  • [Journal Article] Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis2012

    • Author(s)
      Mori S, Kubo S, Akiyoshi T, Yamada S, Miyazaki T, Hotta H, Desaki J, Kishi M, Konishi T, Nishino Y, Miyazawa A, Maruyama N, Shigemoto K
    • Journal Title

      The American Journal of Pathology

      Volume: 180 Issue: 2 Pages: 617-28

    • DOI

      10.1016/j.ajpath.2011.10.031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21200023, KAKENHI-PROJECT-21591102, KAKENHI-PROJECT-21591965, KAKENHI-PROJECT-23592240, KAKENHI-PROJECT-23791009
  • [Journal Article] 3,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis2012

    • Author(s)
      Mori, S. , Kishi, M., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Konishi, T., Maruyama, N., and Shigemoto, K.
    • Journal Title

      Journal of neuroimmunology

      Volume: 245 Issue: 1-2 Pages: 75-78

    • DOI

      10.1016/j.jneuroim.2012.02.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21200023, KAKENHI-PROJECT-21591102, KAKENHI-PROJECT-21591965, KAKENHI-PROJECT-22591698, KAKENHI-PROJECT-23592240, KAKENHI-PROJECT-23791009, KAKENHI-PROJECT-24390228
  • [Presentation] Elucidation of pathogenic mechanism of myasthenia gravis with MuSK antibodies using a novel murine model.2013

    • Author(s)
      Mori, S., Kubo, S., Kishi, M., Konishi, T. and Shigemoto, K.
    • Organizer
      15th International congress of immunology
    • Place of Presentation
      Milano,Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390228
  • [Presentation] A murine model of myasthenia gravis with MuSK antibodies; effect of genetic background.2013

    • Author(s)
      Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. and Shigemoto, K.
    • Organizer
      Myasthenia 2013
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-24390228
  • [Presentation] Examination of the treatment of myasthenia gravis with anti-MuSK antibodies using an experimental autoimmune animal model.2012

    • Author(s)
      Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K.
    • Organizer
      12th International conference on myasthenia gravis and related disorders
    • Place of Presentation
      New York
    • Data Source
      KAKENHI-PROJECT-24390228
  • [Presentation] 抗MuSK抗体陽性重症筋無力症の発症メカニズムに基づく治療薬の検討2012

    • Author(s)
      森秀一、久保幸穂、岸雅彦、小西哲郎、重本和宏
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390228
  • [Presentation] 抗MuSK抗体陽性重症筋無力症の発症メカニズムに基づく治療薬の検討2012

    • Author(s)
      森秀一,久保幸穂,岸雅彦,小西哲郎,重本和宏
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-21591102
  • [Presentation] A novel murine model of myasthenia gravis with MuSK antibodies.2012

    • Author(s)
      Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K.
    • Organizer
      12th International conference on myasthenia gravis and related disorders
    • Place of Presentation
      New York
    • Data Source
      KAKENHI-PROJECT-24390228
  • [Presentation] A novel murine model of myasthenia gravis with MuSK antibodies2012

    • Author(s)
      Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K.
    • Organizer
      9th Japanese-French Symposium for 'muscular dystrophy'
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390228
  • [Presentation] Examination of the treatment of myasthenia gravis with anti-MuSK antibodies using an experimental autoimmune animal model.2012

    • Author(s)
      Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K
    • Organizer
      9th Japanese-French Symposium for 'muscular dystrophy'
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390228
  • 1.  SHIGEMOTO Kazuhiro (40284400)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 2.  MORI Shuuichi (30508677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 3.  EDAMATSU Midori (10735343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  MIYAZAKI Tsuyoshi (50376480)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 5.  KOSHI Katsuo (20710057)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  久保 幸穂 (00280769)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 7.  YAMADA Shigeru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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