KONISHI Tetsuro 小西哲郎

… Alternative Names

小西哲郎コニシテツロウ

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Researcher Number	50426508
Affiliation (Current)	2025: 独立行政法人国立病院機構(宇多野病院臨床研究部), その他部局等, 研究員(移行)
Affiliation (based on the past Project Information) *help	2014: 独立行政法人国立病院機構宇多野病院, 神経内科, 院長 2011: 独立行政法人国立病院機構宇多野病院, 神経内科, 院長
Review Section/Research Field	Except Principal Investigator Neurology
Keywords	Except Principal Investigator 疾患モデル / MuSK / 重症筋無力症 / IgG4 / プロテアソーム / Th2 / 3,4-DAP / ラパマイシン / 疾患モデル動物 / muscle-specifc kinase … More / LRP4 / 自己抗体 / 神経筋シナプス / 重病筋無力症 / muscle-specific kians / 治療薬 / 動物疾患モデル / 神経筋接合部 Less

Elucidation of pathogenic mechanisms and developing new therapies of myasthenia gravis
- Principal Investigator
  
  SHIGEMOTO KAZUHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Elucidation of pathogenic mechanisms of myasthenia gravis caused by MuSK antibodies using a new synchronized experimental animal model
- Principal Investigator
  
  SHIGEMOTO Kazuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

All 2014 2013 2012

All Journal Article Presentation

[Journal Article] 動物モデルによる重症筋無力症の病態機序の解明2014
- Author(s)
  森秀一, 高嶋留美, 小西哲郎, 重本和宏
- Journal Title
  
  神経内科
  
  Volume: 80 Pages: 475-483
- Data Source
  KAKENHI-PROJECT-24390228
[Journal Article] Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis2012
- Author(s)
  Mori S, Kubo S, Akiyoshi T, Yamada S, Miyazaki T, Hotta H, Desaki J, Kishi M, Konishi T, Nishino Y, Miyazawa A, Maruyama N, Shigemoto K
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 180 Issue: 2 Pages: 617-28
- DOI
  10.1016/j.ajpath.2011.10.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200023, KAKENHI-PROJECT-21591102, KAKENHI-PROJECT-21591965, KAKENHI-PROJECT-23592240, KAKENHI-PROJECT-23791009
[Journal Article] 3,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis2012
- Author(s)
  Mori, S. , Kishi, M., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Konishi, T., Maruyama, N., and Shigemoto, K.
- Journal Title
  
  Journal of neuroimmunology
  
  Volume: 245 Issue: 1-2 Pages: 75-78
- DOI
  10.1016/j.jneuroim.2012.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200023, KAKENHI-PROJECT-21591102, KAKENHI-PROJECT-21591965, KAKENHI-PROJECT-22591698, KAKENHI-PROJECT-23592240, KAKENHI-PROJECT-23791009, KAKENHI-PROJECT-24390228
[Presentation] Elucidation of pathogenic mechanism of myasthenia gravis with MuSK antibodies using a novel murine model.2013
- Author(s)
  Mori, S., Kubo, S., Kishi, M., Konishi, T. and Shigemoto, K.
- Organizer
  15th International congress of immunology
- Place of Presentation
  Milano,Italy
- Invited
- Data Source
  KAKENHI-PROJECT-24390228
[Presentation] A murine model of myasthenia gravis with MuSK antibodies; effect of genetic background.2013
- Author(s)
  Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. and Shigemoto, K.
- Organizer
  Myasthenia 2013
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-24390228
[Presentation] Examination of the treatment of myasthenia gravis with anti-MuSK antibodies using an experimental autoimmune animal model.2012
- Author(s)
  Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K.
- Organizer
  12th International conference on myasthenia gravis and related disorders
- Place of Presentation
  New York
- Data Source
  KAKENHI-PROJECT-24390228
[Presentation] 抗MuSK抗体陽性重症筋無力症の発症メカニズムに基づく治療薬の検討2012
- Author(s)
  森秀一、久保幸穂、岸雅彦、小西哲郎、重本和宏
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390228
[Presentation] 抗MuSK抗体陽性重症筋無力症の発症メカニズムに基づく治療薬の検討2012
- Author(s)
  森秀一,久保幸穂,岸雅彦,小西哲郎,重本和宏
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-21591102
[Presentation] A novel murine model of myasthenia gravis with MuSK antibodies.2012
- Author(s)
  Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K.
- Organizer
  12th International conference on myasthenia gravis and related disorders
- Place of Presentation
  New York
- Data Source
  KAKENHI-PROJECT-24390228
[Presentation] A novel murine model of myasthenia gravis with MuSK antibodies2012
- Author(s)
  Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K.
- Organizer
  9th Japanese-French Symposium for 'muscular dystrophy'
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390228
[Presentation] Examination of the treatment of myasthenia gravis with anti-MuSK antibodies using an experimental autoimmune animal model.2012
- Author(s)
  Mori, S., Kubo, S., Akiyoshi, T., Yamada, S., Miyazaki, T., Hotta, H., Desaki, J., Kishi, M., Konishi, T., Maruyama, N. Shigemoto, K
- Organizer
  9th Japanese-French Symposium for 'muscular dystrophy'
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390228

1. SHIGEMOTO Kazuhiro (40284400)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. MORI Shuuichi (30508677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. EDAMATSU Midori (10735343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIYAZAKI Tsuyoshi (50376480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. KOSHI Katsuo (20710057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 久保幸穂 (00280769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. YAMADA Shigeru

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KONISHI Tetsuro 小西 哲郎

小西 哲郎 コニシ テツロウ

Research Projects

Research Products

Co-Researchers

Elucidation of pathogenic mechanisms and developing new therapies of myasthenia gravis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of pathogenic mechanisms of myasthenia gravis caused by MuSK antibodies using a new synchronized experimental animal model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 動物モデルによる重症筋無力症の病態機序の解明2014

Author(s)

Journal Title

Data Source

[Journal Article] Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 3,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] Elucidation of pathogenic mechanism of myasthenia gravis with MuSK antibodies using a novel murine model.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] A murine model of myasthenia gravis with MuSK antibodies; effect of genetic background.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Examination of the treatment of myasthenia gravis with anti-MuSK antibodies using an experimental autoimmune animal model.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 抗MuSK抗体陽性重症筋無力症の発症メカニズムに基づく治療薬の検討2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 抗MuSK抗体陽性重症筋無力症の発症メカニズムに基づく治療薬の検討2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A novel murine model of myasthenia gravis with MuSK antibodies.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] A novel murine model of myasthenia gravis with MuSK antibodies2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Examination of the treatment of myasthenia gravis with anti-MuSK antibodies using an experimental autoimmune animal model.2012

Author(s)

Organizer

Place of Presentation

Data Source

KONISHI Tetsuro 小西哲郎

小西哲郎コニシテツロウ