ISHII Hideto 石井秀人

… Alternative Names

石井秀人イシイヒデト

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Researcher Number	50431953
Other IDs
Affiliation (Current)	2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2007 – 2008: Tokyo Medical and Dental University, 生命倫理研究センター, 特任助教
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator IIMG-CoA還元酵素阻害剤 / AT1受容体拮抗 / リアルタイム解析 / アポE欠損マウス / MAPK / VGAM-1 / ERK-1 / 変異型YY1 / Zinc Finger Domain / 接着分子 … More / アデノウイルスベクター / 細胞接着 / YY1 / 血管内皮細胞 / 動脈硬化症 / 転写調節因子YY1 Less

Research Projects
(1 results)
Research Products
(36 results)

Inhibition of atherosclerosis by transcriptional regulator YY1Principal Investigator
- Principal Investigator
  
  ISHII Hideto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University

All 2008 2007

All Journal Article Presentation

[Journal Article] Angiotensin II type-1 receptor blocker, candesartan, improves brachial-ankle pulse wave velocity independent of its blood pressure lowering effects in type 2 diabetes patients.2008
- Author(s)
  Hideto Ishii, et. al.
- Journal Title
  
  Internal Medicine 47
  
  Pages: 2013-2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] 脂肪吸収のメカニズムに迫る2008
- Author(s)
  石井秀人, 他
- Journal Title
  
  Life Style Medicine 2
  
  Pages: 345-349
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] 内皮細胞の反応2007
- Author(s)
  石井秀人、吉田雅幸
- Journal Title
  
  医学のあゆみ:動脈硬化学UPDATE 221
  
  Pages: 1146-1149
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Candesartan-induced Upregulation Of Transcriptional Regulator Yin Yang 1 Blocks Leukocyte-endothelial Interaction Under Physiological Flow2007
- Author(s)
  Ishii H, Mori D, Sato M, Yoshida M
- Journal Title
  
  Circulation 116
  
  Pages: 292-292
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Yin yang-1 inhibits intimal thickening by repressingp 21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-Cyclin D1 assembly2007
- Author(s)
  Santiago FS., Ishii H., Shafi S., Khurana R., Kanellakis P., Bhindi R., Ramirez M.,Bobik A., Martin J., Chesterman CN., Zachary I., Khachigian LM
- Journal Title
  
  Circulation Research 101(2)
  
  Pages: 146-55
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Cilostazol inhibits monocytic cell adhesion to vascular endotheliumvia upregulation of cAMP.2007
- Author(s)
  Mori D., Ishii H., Kojima C, , Nitta N., Nakajima K., Yoshida M.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis 14
  
  Pages: 213-218
- NAID
  10022606975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Recombinant annexin 2 inhibits the progress of diabetic nephropathy in a diabetic mouse model via recovery of hypercoagulability.2007
- Author(s)
  Ishii H., Hiraoka M, , Tanaka A., Shimokado K., Yoshida M.
- Journal Title
  
  Thrombosis and Haemostasis 97
  
  Pages: 124-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Efficacy of Recombinant Annexin-2 for Fibrinolytic Therapy in a Rat Embolic Stroke Model: A Magnetic Resonance Imaging Study.2007
- Author(s)
  Tanaka Y., Ishii H. Hiraoka M., Miyasaka N., Kuroiwa T., Hajjar KA., Nagaoka T., Duong TQ., Ohno K., Yoshida M.
- Journal Title
  
  Brain Research 1165
  
  Pages: 135-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome.2007
- Author(s)
  Deushi M., Nomura M., Kawakami A., Hraguchi M., Ito M., Okazaki M., Ishii H., Yoshida M.
- Journal Title
  
  FEBS LETTERS 581
  
  Pages: 5664-5670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Yin yang-1 inhibits intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAFl/Cip1-Cdk4-Cyclin D1 assembly.2007
- Author(s)
  Santiago FS.*, Ishii H.*, Shafi S, Khurana R., Kanellakis P., Bhindi R, Ramirez M., Bobik A., Martin J., Chesterman CN., Zachary I, Khachigian LM.
- Journal Title
  
  Circulation Research 101
  
  Pages: 146-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] 炎症、酸化ストレスと動脈硬化2007
- Author(s)
  石井秀人、吉田雅幸
- Journal Title
  
  Medicina 44
  
  Pages: 1460-1462
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] Candesartan-induced Upregulation Of Transcriptional Regulator Yin Yang 1 Blocks Leukocyte-endothelial Interaction Under Physiological Flow.2007
- Author(s)
  Ishii H, Mori D, Sato M, Yoshida M.
- Journal Title
  
  Circulation 116
  
  Pages: 292-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] 動脈硬化巣(プラーク)から見た高脂血症2007
- Author(s)
  石井秀人、吉田雅幸
- Journal Title
  
  Medical Practice 24
  
  Pages: 1202-1206
- Data Source
  KAKENHI-PROJECT-19890065
[Journal Article] 小腸コレステロールトランスポーター阻害薬2007
- Author(s)
  石井秀人、吉田雅幸
- Journal Title
  
  Progress in Medicine 27
  
  Pages: 2887-2889
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 2型糖尿病における心臓足首血管指数CAVIによる動脈硬化評価2008
- Author(s)
  石井秀人, 他
- Organizer
  第51回日本糖尿病学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] Candesartan blocks leukocyte-endothelial interaction under physiological flow via upregulation of transcriptional regulator Yin Yang 12008
- Author(s)
  Ishii H, Mori D, Sato M, Nakagawa T, Yoshida M
- Organizer
  15th International vascular Biology Meeting
- Place of Presentation
  Sydney, NSW, Australia
- Year and Date
  2008-06-02
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] AT1受容体拮抗剤の転写因子YY1を介した細胞接着抑制の分子機構2008
- Author(s)
  中川智香、石井秀人、森大典、佐藤真優子、吉田雅幸
- Organizer
  第40回日本動脈硬化学会学術集会
- Place of Presentation
  筑波
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] Yin Yang 1 function in vascular cells2008
- Author(s)
  Ishii H. Santiago FS, Yoshida M, Khachigian LM
- Organizer
  1st International Symposium on the Biology of the Kruppel-like factors
- Place of Presentation
  東京
- Year and Date
  2008-03-06
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] Candesartan induced transcriptional regulator Yin Yang 1 in activated human endothelial cells and inhibits leukocyte-endothelial interaction under physiological flow.2008
- Author(s)
  Ishii H, Mori D, Sato M, Yoshida M.
- Organizer
  第72回日本循環器学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 転写制御因子Yin Yang 1を介したフルバスタチンの細胞接着抑制機構2008
- Author(s)
  石井秀人, 他
- Organizer
  第40回日本動脈硬化学会学術集会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 2型糖尿病が非侵襲的動脈硬化検査PWV及びCAVIに及ぼす影響2008
- Author(s)
  石井秀人, 他
- Organizer
  第105回日本内科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 転写制御因子Yin Yang 1(YY1)の活性化血管内皮細胞における機能2007
- Author(s)
  佐藤真優子、石井秀人、吉田雅幸
- Organizer
  第39回日本動脈硬化学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] レモンフラボノイドは単球の血管内皮細胞への接着を抑制する2007
- Author(s)
  谷真理子、町田尚子、岸本良美、吉岡絵理、飯塚麻貴、才田恵美、野本佳世子、平田悠美子、田口(柳沢)千恵、石井秀人、吉田雅幸、近藤和雄
- Organizer
  第5回日本機能性食品医用学会総会
- Place of Presentation
  東京
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] Candesartan induced transcriptionalregulator Yin Yang 1 in activated humanendothelial cells and inhibitsleukocyte-endothelial interaction under physiological flow2007
- Author(s)
  Ishii H, Mori D, Sato M, Yoshida M
- Organizer
  第72回日本循環器学会総会
- Place of Presentation
  福岡
- Year and Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] ヒストン脱アセチル化酵素の阻害はMKP-1経路を介して白血球-血管内皮細胞の接着現象を抑制する2007
- Author(s)
  石井秀人、新田智子、出牛三千代、吉田雅幸
- Organizer
  第39回日本動脈硬化学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 転写因子YY1の血管内皮細胞への遺伝子導入2007
- Author(s)
  石井秀人、吉田雅幸
- Organizer
  第52回日本人類遺伝学会大会
- Place of Presentation
  東京
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] Yin yang-1 inhibits intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-Cyclin D1 assembly.2007
- Author(s)
  Ishii H, Santiago FS, Yoshida M, Khachigian LM
- Organizer
  The 8th US-Japan-Asia Dialogue on Cardiovascular Disease
- Place of Presentation
  東京
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] Candesartanは転写制御因子Yin Yang 1(YY1)の発現を誘導し白血球-血管内皮細胞接着を抑制する2007
- Author(s)
  石井秀人、森大典、吉田雅幸
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 遺伝カウンセリングデータベース(本学開発)の教育への活用2007
- Author(s)
  小笹由香、石井秀人、小門穂、水谷修紀、吉田雅幸
- Organizer
  第52回日本人類遺伝学会大会
- Place of Presentation
  東京
- Year and Date
  2007-09-15
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] ACE阻害薬はPKC活性、Rho活性及び細胞内Zn濃度を制御し、単球接着を抑制する2007
- Author(s)
  小島智亜里、石井秀人、新田孝作、吉田雅幸
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 転写制御因子Yin Yang 1(YY1)は活性化血管内皮細胞での白血球接着を抑制する2007
- Author(s)
  石井秀人、佐藤真優子、吉田雅幸
- Organizer
  第15回日本血管生物医学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] レモンフラボノイドによる血管内皮細胞への単球接着作用に関する検討2007
- Author(s)
  谷真理子、町田尚子、岸本良美、吉岡絵里、飯塚麻貴、才田恵美、野本佳代子、平田悠美子、田口(柳沢)千恵、石井秀人、吉田雅幸、近藤和雄
- Organizer
  第29回日本臨床栄養学会総会
- Place of Presentation
  京都
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] Candesartan-induced Upregulation Of Transcriptional Regulator Yin Yang 1 Blocks Leukocyte-endothelial Interaction Under Physiological Flow.2007
- Author(s)
  Ishii H, Mori D, Sato M, Yoshida M.
- Organizer
  The American Heart Association Scientific Meeting 2007
- Place of Presentation
  米国オーランド
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] レモンフラボノイドは単球の血管内皮細胞への接着を抑制する2007
- Author(s)
  谷真理子、川上明夫、石井秀人、岸本良美、近藤和雄、吉田雅幸
- Organizer
  第15回日本血管生物医学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] 2型等糖尿病患者の脈波伝搬速度(baPWV)と炎症マーカーに与えるAT1受容体拮抗剤とカルシウム拮抗剤の影響2007
- Author(s)
  石井秀人、塚田豊弘、吉田雅幸
- Organizer
  第104回日本内科学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-04-03
- Data Source
  KAKENHI-PROJECT-19890065
[Presentation] ACE阻害薬はPKC活性、Rho活性および細胞内Zn濃度を制御し、単球接着を抑制する2007
- Author(s)
  小島智亜里、川上明夫、石井秀人、吉田雅幸
- Organizer
  第15回日本血管生物医学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19890065

ISHII Hideto 石井 秀人

石井 秀人 イシイ ヒデト

Research Projects

Research Products

Inhibition of atherosclerosis by transcriptional regulator YY1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Angiotensin II type-1 receptor blocker, candesartan, improves brachial-ankle pulse wave velocity independent of its blood pressure lowering effects in type 2 diabetes patients.2008

Author(s)

Journal Title

Data Source

[Journal Article] 脂肪吸収のメカニズムに迫る2008

Author(s)

Journal Title

Data Source

[Journal Article] 内皮細胞の反応2007

Author(s)

Journal Title

Data Source

[Journal Article] Candesartan-induced Upregulation Of Transcriptional Regulator Yin Yang 1 Blocks Leukocyte-endothelial Interaction Under Physiological Flow2007

Author(s)

Journal Title

Data Source

[Journal Article] Yin yang-1 inhibits intimal thickening by repressingp 21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-Cyclin D1 assembly2007

Author(s)

Journal Title

Data Source

[Journal Article] Cilostazol inhibits monocytic cell adhesion to vascular endotheliumvia upregulation of cAMP.2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Recombinant annexin 2 inhibits the progress of diabetic nephropathy in a diabetic mouse model via recovery of hypercoagulability.2007

Author(s)

Journal Title

Data Source

[Journal Article] Efficacy of Recombinant Annexin-2 for Fibrinolytic Therapy in a Rat Embolic Stroke Model: A Magnetic Resonance Imaging Study.2007

Author(s)

Journal Title

Data Source

[Journal Article] Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome.2007

Author(s)

Journal Title

Data Source

[Journal Article] Yin yang-1 inhibits intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAFl/Cip1-Cdk4-Cyclin D1 assembly.2007

Author(s)

Journal Title

Data Source

[Journal Article] 炎症、酸化ストレスと動脈硬化2007

Author(s)

Journal Title

Data Source

[Journal Article] Candesartan-induced Upregulation Of Transcriptional Regulator Yin Yang 1 Blocks Leukocyte-endothelial Interaction Under Physiological Flow.2007

Author(s)

Journal Title

Data Source

[Journal Article] 動脈硬化巣(プラーク)から見た高脂血症2007

Author(s)

Journal Title

Data Source

[Journal Article] 小腸コレステロールトランスポーター阻害薬2007

Author(s)

Journal Title

Data Source

[Presentation] 2型糖尿病における心臓足首血管指数CAVIによる動脈硬化評価2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Candesartan blocks leukocyte-endothelial interaction under physiological flow via upregulation of transcriptional regulator Yin Yang 12008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] AT1受容体拮抗剤の転写因子YY1を介した細胞接着抑制の分子機構2008

Author(s)

ISHII Hideto 石井秀人

石井秀人イシイヒデト