TAKAHASHI KEN 高橋賢

… Alternative Names

TAKAHASHI Ken 高橋賢

高橋賢タカハシケン

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Researcher Number	50432258
Other IDs	https://orcid.org/0000-0002-7580-8691
Affiliation (Current)	2024: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help	2024: 岡山大学, 医歯薬学域, 准教授 2020 – 2023: 岡山大学, 医歯薬学域, 研究准教授 2020: 岡山大学, 医歯薬学総合研究科, 研究准教授 2015 – 2019: 岡山大学, 医歯薬学総合研究科, 助教 2017: 岡山大学, 医歯(薬)学総合研究科, 助教 … More 2016: 岡山大学, 医歯薬学総合研究科システム生理学, 助教 2012 – 2015: 岡山大学, 医歯(薬)学総合研究科, 助教 2014: 岡山大学, 医歯薬学総合研究科システム生理学, 助教 2006: 名古屋大学, 大学院医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Basic Section 90110:Biomedical engineering-related Except Principal Investigator Biomedical engineering/Biomaterial science and engineering / Plastic surgery / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 90:Biomedical engineering and related fields / Complex systems / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords	Principal Investigator 虚血再灌流障害 / 心筋梗塞 / 腎臓移植 / 脳梗塞 / 臓器チップ / iPS細胞 / CRISPR/Cas9 / TRPM4 / 一酸化窒素(NO) / 活性酸素種(ROS) … More / iPS / 虚血再灌流 / 腎移植 / 補体活性化 / 生体分子 / 生理学 / 循環器・高血圧 / 細胞・組織 / TRPM2 / ラット心筋細胞株H9c2 / TRPM4チャネル / 細胞内ATP濃度 / ミトコンドリア膜電位 / MALDI-TOF … More Except Principal Investigator iPS細胞 / 機械刺激 / メカノバイオロジー / メカニカルストレス / 再生医学 / 3次元全層培養皮膚 / メカノメディスン / エクソソーム / 転移ニッチ / マクロファージ / 癌 / 細胞外小胞 / 活性酸素種 / 細胞内カルシウムイオン / 剪断応力 / 伸展刺激 / 圧力刺激 / 高圧力環境 / 細胞間interaction / 基底膜 / 伸展培養 / human skin equivalent / 動物細胞 / 力学的ストレス / メカノセンシング / 細胞内シグナル伝達 / 過重力 / 微小重力 / 模擬微小重力 / 遠心顕微鏡 / 機械刺激受容チャネル / 血管内皮細胞 / PKC / YAP / 回転蛍光顕微鏡 / 圧力 / 重力 / 宇宙医学 / 宇宙生物学 / 宇宙 / 心筋幹細胞 / 人工多能性幹細胞 / 心筋細胞 / 初期胚 / 生殖器 / 循環器 / 移植・再生医療 / 着床前胚 / 体外受精胚 / 心臓幹細胞 / 人工多能性幹細胞(iPSC) / 生殖補助医療 / 再生医療 / 心不全 / 機械的刺激 / 力学的刺激 / 心臓再生医療 / 自己集合成ペプチドゲル / ３次元全層培養皮膚 / 自己集合性ペプチドゲル / 皮脂厚 / 表面麻酔 / ヒト / シミュレーション / 三次元有限要素法 / 圧痛 / 筋性疼痛 / 経皮的圧痛測定法 / 筋内応力分布 / コンピュータシミュレーション / 有限要素法 / 筋圧痛閾値 Less

Roles of cancer extracellular vesicles in hijacking macrophages and metastatic niche formation
- Principal Investigator
  
  江口傑徳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Okayama University
新規メカニカル負荷装置の開発を通した次世代メカノメディスンへの挑戦
- Principal Investigator
  
  成瀬恵治
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Okayama University
Elucidation of mechanism of ischemia-reperfusion injury using heart-, brain-, and kidney-on-a-chipsPrincipal Investigator
- Principal Investigator
  
  高橋賢
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Okayama University
Elucidation of the mechanism of arrhythmia in myocardial infarction in an organ-on-a-chipPrincipal Investigator
- Principal Investigator
  
  Takahashi Ken
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University
Elucidation of the mechanism of arrhythmia in cardiac ischemia-reperfusion injury by imaging technologyPrincipal Investigator
- Principal Investigator
  
  Takahashi Ken
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University
Mechanosensing Mechanisms for Sensing Mechanical Stress Including Gravitational Changes
- Principal Investigator
  
  Naruse Keiji
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Okayama University
心疾患治療に向けた革新的次世代メカノ組織工学・再生医療の創生
- Principal Investigator
  
  成瀬恵治
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University
Mechanomedicine: Application of mechanobiological engineering to regenerative and reproductive medicine
- Principal Investigator
  
  NARUSE Keiji
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University
The effect of stretch stimuli on human skin equivalents
- Principal Investigator
  
  Hasegawa Kenjiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Kawasaki Medical School
Mechanical stretch on Human skin equivalents with a new peptide scaffold
- Principal Investigator
  
  TOKUYAMA Eijiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Okayama University
深部組織における痛覚の測定法に関するシミュレーション及び実験的研究
- Principal Investigator
  
  水村和枝
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nagoya University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2006 2005 Other

All Journal Article Presentation Book Patent

[Book] Mechanobiology: Exploitation for Medical Benefit2017
- Author(s)
  Takahashi K, Piao H, Naruse K
- Total Pages
  410
- Publisher
  Blackwell Publishing
- Data Source
  KAKENHI-PROJECT-26220203
[Book] Mechanobiology: Exploitation for Medical Benefit2017
- Author(s)
  Takahashi K, Piao H, Naruse K
- Total Pages
  410
- Publisher
  Blackwell Publishing
- Data Source
  KAKENHI-PLANNED-15H05936
[Book] Mechanobiology2017
- Author(s)
  Takahashi K, Piao H, Naruse K
- Total Pages
  14
- Publisher
  Wiley-Blackwell
- ISBN
  9781118966143
- Data Source
  KAKENHI-PLANNED-15H05936
[Journal Article] Functional analysis of a kidney-on-a-chip using human renal proximal tubular epithelial cells and human umbilical vein endothelial cells2022
- Author(s)
  Yin Liang, Mengxue Wang, Yun Liu, Keiji Naruse, Ken Takahashi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 72(S1) Pages: 146-146
- Data Source
  KAKENHI-PROJECT-21H04960
[Journal Article] Live imaging of nitric oxide release in vascular endothelial cells in response to mechanical stimuli on an organ chip2022
- Author(s)
  Takahashi K、Liu Y、Wang M、Liang Y、Naruse K
- Journal Title
  
  European Heart Journal
  
  Volume: 43 Issue: Supplement_2
- DOI
  10.1093/eurheartj/ehac544.3027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04960, KAKENHI-PROJECT-20H04518
[Journal Article] Sphingosine-1-Phosphate Induces ATP Release via Volume-Regulated Anion Channels in Breast Cell Lines2022
- Author(s)
  Furuya K, Takahashi Y, Hirata H, Kobayashi T, Sokabe M
- Journal Title
  
  J Physiol Sci
  
  Volume: 72 (suppl 1) Issue: S1 Pages: 109-109
- DOI
  10.1186/s12576-022-00851-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06851, KAKENHI-PROJECT-22K06831, KAKENHI-PROJECT-21K19212, KAKENHI-PROJECT-20H03219, KAKENHI-PROJECT-20H04518, KAKENHI-PROJECT-19K07302, KAKENHI-PROJECT-20K07728
[Journal Article] Role of the TRPM4 channel in mitochondrial function, calcium release, and ROS generation in oxidative stress2021
- Author(s)
  Wang Chen, Chen Jian, Wang Mengxue, Naruse Keijij, Takahashi Ken
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: accepted
- NAID
  120007099346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0168
[Journal Article] Development of a human heart-on-a-chip model using induced pluripotent stem cells, fibroblasts and endothelial cells2021
- Author(s)
  Liu Y、Wang M、Liang Y、Naruse K、Takahashi K
- Journal Title
  
  European Heart Journal
  
  Volume: 42 Issue: Supplement_1
- DOI
  10.1093/eurheartj/ehab724.3190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04518
[Journal Article] Production of TRPM4 knockout cell line using rat cardiomyocyte H9c22021
- Author(s)
  Wang Chen、Maeda Masakazu、Chen Jian、Wang Mengxue、Naruse Keiji、Takahashi Ken
- Journal Title
  
  MethodsX
  
  Volume: 8 Pages: 101404-101404
- DOI
  10.1016/j.mex.2021.101404
- NAID
  120007168218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04518
[Journal Article] Role of the TRPM4 channel in mitochondrial function, calcium release, and ROS generation in oxidative stress2021
- Author(s)
  Wang Chen、Chen Jian、Wang Mengxue、Naruse Keiji、Takahashi Ken
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 566 Pages: 190-196
- DOI
  10.1016/j.bbrc.2021.03.077
- NAID
  120007099346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04960, KAKENHI-PROJECT-20H04518
[Journal Article] Production of TRPM4 knockout cell line using rat cardiomyocyte H9c22021
- Author(s)
  Wang C, Maeda M, Chen J, Wang M, Naruse K, Takahashi K
- Journal Title
  
  MethodsX
  
  Volume: 8 Pages: 101404-101404
- NAID
  120007168218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04960
[Journal Article] Systematic Understanding of Pathophysiological Mechanisms of Oxidative Stress-Related Conditions?Diabetes Mellitus, Cardiovascular Diseases, and Ischemia?Reperfusion Injury2021
- Author(s)
  Wang Mengxue, Liu Yun, Liang Yin, Naruse Keiji, Takahashi Ken
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 8 Pages: 649785-649785
- DOI
  10.3389/fcvm.2021.649785
- NAID
  120007037390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0168, KAKENHI-PROJECT-20H04518
[Journal Article] The Mechanisms of the Development of Atherosclerosis in Prediabetes2021
- Author(s)
  Liang Yin、Wang Mengxue、Wang Chen、Liu Yun、Naruse Keiji、Takahashi Ken
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 8 Pages: 4108-4108
- DOI
  10.3390/ijms22084108
- NAID
  120007034439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04960, KAKENHI-PROJECT-20H04518
[Journal Article] Systematic understanding of pathophysiological mechanisms of oxidative stress-related conditions-diabetes mellitus, cardiovascular diseases, and ischemia-reperfusion injury.2021
- Author(s)
  Wang M, Liu Y, Liang Y, Naruse K, Takahashi K
- Journal Title
  
  Front Cardiovasc Med
  
  Volume: 8 Pages: 649785-649785
- NAID
  120007037390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04960
[Journal Article] Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived Cardiomyocytes2020
- Author(s)
  Liu Yun, Liang Yin, Wang Mengxue, Wang Chen, Wei Heng, Naruse Keiji, Takahashi Ken
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: - Issue: 159
- DOI
  10.3791/61104
- NAID
  120006872429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0168
[Journal Article] Development of a model of ischemic heart disease using cardiomyocytes differentiated from human induced pluripotent stem cells2019
- Author(s)
  Wei Heng、Wang Chen、Guo Rui、Takahashi Ken、Naruse Keiji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 520 Issue: 3 Pages: 600-605
- DOI
  10.1016/j.bbrc.2019.09.119
- NAID
  120006795604
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0168
[Journal Article] L-type calcium channel modulates mechanosensitivity of the cardiomyocyte cell line H9c22019
- Author(s)
  Ken Takahashi, Shogo Hayashi, Mari Miyajima, Marei Omori, Jing Wang, Keiko Kaihara, Masatoshi Morimatsu, Chen Wang, Jian Chen, Gentaro Iribe, Keiji Naruse, Masahiro Sokabe
- Journal Title
  
  Cell Calcium
  
  Volume: 79 Pages: 68-74
- DOI
  10.1016/j.ceca.2019.02.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936, KAKENHI-PROJECT-26220203, KAKENHI-ORGANIZER-15H05935
[Journal Article] Human gingival fibroblast feeder cells promote maturation of induced pluripotent stem cells into cardiomyocytes2018
- Author(s)
  Matsuda Y, Takahashi K, Kamioka H, Naruse K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 503(3) Issue: 3 Pages: 1798-1804
- DOI
  10.1016/j.bbrc.2018.07.116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0168, KAKENHI-PROJECT-26220203
[Journal Article] 特集：宇宙の極限環境から生命体の可塑性をさぐる--1.重力変動の生理機能への影響　細胞の重力応答機構--2018
- Author(s)
  高橋　賢、佐々並三紗、長田　仁、成瀬恵治
- Journal Title
  
  生体の科学
  
  Volume: 62 Pages: 106-109
- Data Source
  KAKENHI-PLANNED-15H05936
[Journal Article] Role of the TRPM4 Channel in Cardiovascular Physiology and Pathophysiology2018
- Author(s)
  Wang C, Naruse K, Takahashi K
- Journal Title
  
  Cells
  
  Volume: 7(6) Issue: 6 Pages: 62-62
- DOI
  10.3390/cells7060062
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0168, KAKENHI-PROJECT-26220203, KAKENHI-PROJECT-16K01356
[Journal Article] Matrix stiffness regulates migration of human lung fibroblasts2017
- Author(s)
  Asano Shuichi、Ito Satoru、Takahashi Kota、Furuya Kishio、Kondo Masashi、Sokabe Masahiro、Hasegawa Yoshinori
- Journal Title
  
  Physiol Rep
  
  Volume: 5 Issue: 9 Pages: e13281-e13281
- DOI
  10.14814/phy2.13281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08174, KAKENHI-PROJECT-16K09578, KAKENHI-PLANNED-15H05936
[Journal Article] Effect of Oxidative Stress on Cardiovascular System in Response to Gravity2017
- Author(s)
  Takahashi Ken, Okumura Hiroki, Guo Rui, Naruse Keiji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 7 Pages: 1426-1426
- DOI
  10.3390/ijms18071426
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01356, KAKENHI-PROJECT-26220203
[Journal Article] TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes2017
- Author(s)
  Yamaguchi Y, Iribe G, Kaneko T, Takahashi K, Numaga-Tomita T, Nishida M, Birnbaumer L, Naruse K.
- Journal Title
  
  J. Physiol. Sci.
  
  Volume: 印刷中 Issue: 2 Pages: 1-12
- DOI
  10.1007/s12576-016-0519-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-26282121, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-26220203
[Journal Article] Real-time imaging of mechanically and chemically induced ATP release in human lung fibroblasts2017
- Author(s)
  Takahashi Kota、Ito Satoru、Furuya Kishio、Asano Shuichi、Sokabe Masahiro、Hasegawa Yoshinori
- Journal Title
  
  Respir Physiol Neurobiol
  
  Volume: 242 Pages: 96-101
- DOI
  10.1016/j.resp.2017.04.008
- NAID
  120006343663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08174, KAKENHI-PROJECT-16K09578, KAKENHI-PLANNED-15H05936
[Journal Article] Response to mechanical stimulus and cardiovascular homeostasis.2016
- Author(s)
  Takahashi K, Naruse K
- Journal Title
  
  Clin Calcium
  
  Volume: 26(12) Pages: 1671-1676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26220203
[Journal Article] Response to mechanical stimulus and cardiovascular homeostasis.2016
- Author(s)
  Takahashi K, Naruse K
- Journal Title
  
  Clin Calcium
  
  Volume: 26(12) Pages: 1671-1676
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05936
[Journal Article] Mechanical Stretch on Human Skin Equivalents Increases the Epidermal Thickness and Develops the Basement Membrane2015
- Author(s)
  Eijiro Tokuyama, Yusuke Nagai, Ken Takahashi, Keiji Naruse, Yoshihiro Kimata
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 11 Pages: e0141989-e0141989
- DOI
  10.1371/journal.pone.0141989
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462732
[Journal Article] 心臓・血管の組織工学と再生医療2014
- Author(s)
  高橋賢、成瀬恵治
- Journal Title
  
  Jinko Zoki
  
  Volume: 43 Issue: 3 Pages: 206-208
- DOI
  10.11392/jsao.43.206
- NAID
  130004912113
- ISSN
  0300-0818, 1883-6097
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-26220203
[Journal Article] 皮脂厚の違いによって経皮的圧刺激の効果は異なるか?-経皮的圧刺激に対する組織内応力分布の3次元有限要素法による推定2006
- Author(s)
  高橋賢, 水村和枝
- Journal Title
  
  日本生理学雑誌 68巻1号
  
  Pages: 36-36
- Data Source
  KAKENHI-PROJECT-17659066
[Journal Article] Influence of surface anesthesia on the pressure pain threshold measured with different-sized probes.2005
- Author(s)
  K.Takahashi, T.Taguchi, K.Itoh, K.Okada, K.Kawakita, K.Mizumura.
- Journal Title
  
  Somatosensory and Motor Research 22(4)
  
  Pages: 299-305
- Data Source
  KAKENHI-PROJECT-17659066
[Patent] 心筋細胞の作製方法2020
- Inventor(s)
  高橋賢、出射明美、成瀬恵治
- Industrial Property Rights Holder
  高橋賢、出射明美、成瀬恵治
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17KK0168
[Patent] 蛍光遠心顕微鏡2016
- Inventor(s)
  成瀬恵治、高橋　賢、森松賢順
- Industrial Property Rights Holder
  成瀬恵治、高橋　賢、森松賢順
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-043814
- Filing Date
  2016-03-07
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Facilitated differentiation of induced pluripotent stem cells into cardiomyocytes in a microfluidic chip2023
- Author(s)
  Rumaisa Kamran, Yun Liu, Qiang Li, Keiji Naruse, Ken Takahashi
- Organizer
  第100回日本生理学会大会日本生理学会
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Facilitated differentiation of induced pluripotent stem cells into cardiomyocytes in a microfluidic chip2023
- Author(s)
  Kamran R, Liu Y, Li Q, Naruse K, Takahashi K
- Organizer
  日本理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Development of a lung fibrosis model using lung epithelial cells, fibroblasts, and vascular endothelial cells2023
- Author(s)
  Li Q, Liu Y, Wang M, LiangnY,Naruse K, Takahashi K
- Organizer
  日本理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Development of a lung fibrosis model using lung epithelial cells, fibroblasts, and vascular endothelial cells2023
- Author(s)
  Qiang LI, Yun LIU, Mengxue WANG, Yin LIANG, Keiji NARUSE, Ken TAKAHASHI
- Organizer
  第100回日本生理学会大会日本生理学会
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Human heart-on-a-chip that responds to noradrenaline and mechanical stimulus2022
- Author(s)
  Takahashi K, Liu Y, Wang M, Liang Y, Naruse K
- Organizer
  ESC Congress 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Functional analysis of a kidney-on-a-chip using human renal proximaltubular epithelial cells and human umbilical vein endothelial cells.2022
- Author(s)
  Takahashi K, Liang Y,Wang M,Liu Y, Naruse K
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Functional analysis of a kidney-on-a-chip using human renal proximal tubularepithelial cells and human umbilical vein endothelial cells2022
- Author(s)
  Yin Liang, Mengxue Wang, Yun Liu, Keiji Naruse, Ken Takahashi
- Organizer
  The 99th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Human heart-on-a-chip that responds to noradrenaline and mechanical stimulus2022
- Author(s)
  Takahashi K, Liu Y, Wang M, Kamran R, Naruse K
- Organizer
  Cell Symposium: Advances in Therapeutic Applications of Stem Cells
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Mechanical stretch facilitates cardiomyocyte differentiation of human-induced pluripotent stem cells co-cultured with human gingival fibroblasts Invited2022
- Author(s)
  Takahashi K, Idei H, Wang M, Matsuda Y, Kamioka H, Naruse K
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Development of a lung fibrosis model on transwells2022
- Author(s)
  李強、劉雲、王夢雪、梁茵、成瀬恵治、高橋賢
- Organizer
  第74回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Live imaging of nitric oxide release in vascular endothelial cells in response to mechanical stimuli on an organ chip2022
- Author(s)
  Takahashi K, Liu Y, Wang M, Liang Y, Naruse K
- Organizer
  ESC Congress 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Cancer-on-a-chip: 蛍光エクソソーム技術とマイクロ流体チップを用いた腫瘍-単球コミュニケーションモデルの構築2022
- Author(s)
  山本結, 高橋賢, 岡元邦彰, 江口傑徳
- Organizer
  SCRP日本代表選抜大会
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Mechanical stretch facilitates cardiomyocyte differentiation of human-induced pluripotent stem cells co-cultured with human gingival fibroblasts2022
- Author(s)
  Ken Takahashi, Harumi Idei, Mengxue Wang, Yusuke Matsuda, Hiroshi Kamioka, Keiji Naruse
- Organizer
  9th World Congress of Biomechanics 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] 重力が老化に及ぼす影響2022
- Author(s)
  高橋　賢、成瀬恵治
- Organizer
  第61回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Development of a lung fibrosis model on transwells2022
- Author(s)
  李強, 劉雲, 王夢雪, 梁茵, 成瀬恵治, 高橋賢
- Organizer
  第74回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Live imaging of nitric oxide release in vascular endothelial cells in response to mechanical stimuli on an organ chip2022
- Author(s)
  Ken Takahashi, Yun Liu, Mengxue Wang, Rumaisa Kamran, Keiji Naruse
- Organizer
  Cell Symposium: Advances in Therapeutic Application of Stem Cells 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Development of a human heart-on-a-chip model using induced pluripotent stem cells, fibroblasts and endothelial cells2021
- Author(s)
  Liu Y, Wang M, Liang Y, Naruse K, Takahashi K
- Organizer
  ESC Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] 臓器チップを用いたヒト臓器モデルの開発2021
- Author(s)
  高橋賢
- Organizer
  日本生体医工学会関西支部講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Development and functional characterization of a model of human heart using organ-on-a-chip2021
- Author(s)
  Takahashi K
- Organizer
  The 3rd International Conference of Microfluidics, Nanofluidics and Lab-on-a-Chip
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Development of a model of human heart using organ-on-a-chip2021
- Author(s)
  Takahashi K
- Organizer
  The 60th Annual Conference of Japanese Society for Medical and Biological Engineering
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Kidney-on-a-chip model using human renal proximal tubular epithelial cells and human umbilical vein endothelial cells2021
- Author(s)
  Yin Liang, Mengxue Wang, Keiji Naruse, Ken Takahashi
- Organizer
  The 98th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Optimization of the cardiac differentiation of human pluripotent stem cells2021
- Author(s)
  Liu Yun, Mengxue Wang, Kenji Naruse, Ken Takahashi
- Organizer
  The 98th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Establishing an artificial heart model on a chip by using cardiomyocytes2021
- Author(s)
  Wang Mengxue, Yun Liu, Kenji Naruse, Ken Takahashi
- Organizer
  The 98th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Optimization of the cardiac differentiation of human pluripotent stem cells2021
- Author(s)
  Liu Y, Wang M, Naruse K, Takahashi K
- Organizer
  The 98th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Development of a human heart-on-a-chip model using induced pluripotent stem cells, fibroblasts and endothelial cells.2021
- Author(s)
  Liu Y, Wang M, Liang Y, Naruse K, Takahashi K
- Organizer
  ESC Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Development of a model of human heart using organ-on-a-chip2021
- Author(s)
  Takahashi K，Liu Y,Wang M,Liang Y, Naruse K
- Organizer
  第60回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-21H04960
[Presentation] Development of human organ model using organ-on-a-chip and its application2021
- Author(s)
  Takahashi K
- Organizer
  The 124th Seminar of the BME Society of Okayama Prefecture
- Invited
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Establishing an artificial heart model on a chip by using cardiomyocytes differentiated from human induced pluripotent stem cells2021
- Author(s)
  Wang M, Liu Y, Naruse K, Takahashi K
- Organizer
  The 98th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-20H04518
[Presentation] Kidney-on-a-chip model using human renal proximal tubular epithelial cells and human umbilical vein endothelial cells2021
- Author(s)
  Yin Liang, Mengxue Wang, Keiji Naruse, Ken Takahashi
- Organizer
  The 98th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Development of microfluidic cell culture system in preparation for human organ on a chip2020
- Author(s)
  高橋賢, 王梦雪, 劉雲, 梁茵, 王晨, 成瀬恵治
- Organizer
  第59会日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] ヒト臓器チップを用いた臓器機能評価2020
- Author(s)
  高橋賢
- Organizer
  CBI学会2020年大会
- Invited
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Ischemia-reperfusion injury2019
- Author(s)
  Takahashi K
- Organizer
  2019 International Conference for Leading and Young Medical Scientists
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Roles of the TRPM4 channel in mitochondrial function, ROS generation, and calcium release in myocardial ischemia-reperfusion injury2019
- Author(s)
  Wang C, Naruse K, Takahashi K
- Organizer
  2019 International Conference for Leading and Young Medical Scientists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Mechanobiology and its application to medical problem solving2019
- Author(s)
  Takahashi K
- Organizer
  2019 International Conference on Biology and Medical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Roles of the TRPM4 channel in mitochondrial function, ROS generation, and calcium release in myocardial ischemia-reperfusion injury2019
- Author(s)
  Wang C, Chen J, Naruse K, Takahashi K
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Mechanobiology and its application to medical problem solving2019
- Author(s)
  Takahashi K
- Organizer
  2019 International Conference on Biology and Medical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] 心筋分化誘導に対する細胞培養の次元の影響2018
- Author(s)
  多田千香、高橋　賢、成瀬恵治
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] Cellular model of ischemic heart disease using human induced pluripotent stem cells2018
- Author(s)
  Wei H, Wang C, Takahashi K, Naruse K
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] Cellular model of ischemic heart disease using human induced pluripotent stem cells2018
- Author(s)
  Wei H, Wang C, Takahashi K, Naruse K
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] Cellular model of ischemic heart disease using human induced pluripotent stem cells2018
- Author(s)
  Wei H, Wang C, Takahashi K, Naruse K
- Organizer
  The 95th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] iPS 細胞の心筋分化誘導における血管内皮細胞の影響2018
- Author(s)
  Tada C, Takahashi K, Morimatsu M, Naruse K
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] TRPM4チャネルは虚血再灌流障害による細胞損傷に関わる：ヒトiPS細胞由来心筋細胞2018
- Author(s)
  王　晨、魏　恒、成瀬惠治、高橋　賢
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] TRPM4 channel is involved in cellular damage caused by simulated ischemia-reperfusion injury: study of human iPSC-derived cardiomyocytes2018
- Author(s)
  Wang C, Wei H, Naruse K, Takahashi K
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] TRPM4 channel is involved in cellular damage caused by simulated ischemia-reperfusion injury: study of human iPSC-derived cardiomyocytes2018
- Author(s)
  Wang C, Wei H, Naruse K, Takahashi K
- Organizer
  The 95th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] TRPM4 channel is involved in cellular damage caused by simulated ischemia-reperfusion injury: study of human iPSC-derived cardiomyocytes2018
- Author(s)
  Wang C, Wei H, Naruse K, Takahashi K
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] Effect of dimensional factor of cell culture on cardiac differentiation of human induced pluripotent stem cells2018
- Author(s)
  Tada C, Takahashi K, Naruse K
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17KK0168
[Presentation] ヒトiPS細胞を用いた虚血性心疾患モデルの構築2018
- Author(s)
  魏　恒、王　晨、高橋　賢、成瀬恵治
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] Effect of dimensional factor of cell culture on cardiac differentiation of human induced pluripotent stem cells2018
- Author(s)
  Tada C, Takahashi K, Naruse K
- Organizer
  The 95th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] ヒトiPS細胞を用いた虚血性心疾患モデルの構築2017
- Author(s)
  魏　恒、王　晨、高橋　賢、成瀬恵治
- Organizer
  第69回日本生理学中国・四国地方会
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] Simultaneous mapping of multiple proteins in heart using matrix-assisted laser desorption/ionization imaging mass spectrometry2017
- Author(s)
  Takahashi K, Naruse K
- Organizer
  European Society of Cardiology Annual Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] Simultaneous mapping of multiple proteins in heart using matrix-assisted laser desorption/ionization imaging mass spectrometry2017
- Author(s)
  Takahashi K, Naruse K
- Organizer
  European Society of Cardiology Annual Congress 2017
- Place of Presentation
  Barcelona
- Year and Date
  2017-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] Coarse grained molecular dynamics simulation of mammalian mechanosensitive ion channel TRPV22017
- Author(s)
  Takahashi K
- Organizer
  3rd International Symposium on Mechanobiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] Coarse grained molecular dynamics simulation of mammalian mechanosensitive ion channel TRPV22017
- Author(s)
  Takahashi K
- Organizer
  International Symposium on Mechanobiology 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] ヒトiPS細胞を用いた虚血性心疾患モデルの構築2017
- Author(s)
  魏恒，王晨，高橋賢，成瀬恵治
- Organizer
  第69回日本生理学会中国・四国地方会
- Data Source
  KAKENHI-PROJECT-16K01356
[Presentation] Simultaneous mapping of multiple proteins in heart using matrix-assisted laser desorption/ionization imaging mass spectrometry2017
- Author(s)
  Takahashi K, Naruse K
- Organizer
  European Society of Cardiology Annual Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] メカノ医工学を駆使した再生医療・生殖医療への展開2017
- Author(s)
  高橋　賢、王　英正、入部玄太郎、松浦宏治、成瀬恵治
- Organizer
  第56回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] TRPC3 participates in the angiotensin II type 1 receptor-dependent slow force response to stretch in mouse cardiomyocytes.2016
- Author(s)
  Yamaguchi Y, Iribe G, Kaneko T, Takahashi K, Numaga-Tomita T, Nishida M, Birnbaumer L, Naruse K
- Organizer
  45th European Muscle Conference
- Place of Presentation
  France
- Year and Date
  2016-09-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] 重力変化を含む力学的ストレスに対するメカノセンシング機構2016
- Author(s)
  高橋賢
- Organizer
  新領域研究「宇宙に生きる」2016ワークショップ
- Place of Presentation
  東京
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] High hydrostatic pressure induces signal transduction of MAPK pathway.2016
- Author(s)
  Morimatsu M, Fujita A, Takahashi K, Naruse K
- Organizer
  Biophysical Society
- Place of Presentation
  Singapore
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] High hydrostatic pressure induces cytoskeletal organization and signal transduction.2016
- Author(s)
  Morimatsu M, Fujita A, Takahashi K, Naruse K
- Organizer
  2016 American Society for Cell Biology
- Place of Presentation
  San Francisco
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] TRPC3 participates in the angiotensin II type 1 receptor-dependent slow force response to stretch in mouse cardiomyocytes.2016
- Author(s)
  Yamaguchi Y, Iribe G, Kaneko T, Takahashi K, Numaga-Tomita T, Nishida M, Birnbaumer L, Naruse K
- Organizer
  45th European Muscle Conference
- Place of Presentation
  France
- Year and Date
  2016-09-02
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05936
[Presentation] High hydrostatic pressure induces signal transduction of MAPK pathway.2016
- Author(s)
  Morimatsu M, Fujita A, Takahashi K, Naruse K.
- Organizer
  Biophysical Society
- Place of Presentation
  Singapore
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] High hydrostatic pressure induces cytoskeletal organization and signal transduction.2016
- Author(s)
  Morimatsu M, Fujita A, Takahashi K, Naruse K
- Organizer
  2016 American Society for Cell Biology
- Place of Presentation
  San Francisco
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] Contractile function of reconstituted cardiac tissue is facilitated by mechanical stretch2015
- Author(s)
  Sakai N, Takahashi K, Naruse K
- Organizer
  The 92nd Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Kobe
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] A search for scaffold condition suitable for inducing cardiac differentiation of induced pluripotent stem cells.2015
- Author(s)
  Matsuda Y, Sakai N, Takahashi K, Naruse K
- Organizer
  37th annual international conference of the IEEE Engineering in Medicine and Biology Society
- Place of Presentation
  Italy
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220203
[Presentation] 伸展刺激が３次元全層培養皮膚に及ぼす影響
- Author(s)
  徳山英二郎、永井　祐介、高橋　賢、成瀬　恵治
- Organizer
  第12回日本再生医療学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24592713

1. NARUSE Keiji (40252233)

# of Collaborated Projects: 7 results

# of Collaborated Products: 49 results
2. 入部玄太郎 (90284885)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. TOKUYAMA Eijiro (90379785)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 王英正 (50372579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. Hasegawa Kenjiro (90197674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 水村和枝 (00109349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 川喜田健司 (60076049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 梅田雅宏 (60223608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松浦宏治 (70443223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 曽我部正博 (10093428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 小林剛 (40402565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 西山雅祥 (10346075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 片野坂友紀 (60432639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 森松賢順 (70580934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 江口傑徳 (20457229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 河合穂高 (10803687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岡元邦彰 (10311846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 冨樫庸介 (80758326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 武部克希 (61000104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Wang Chen

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
21. Miyaji Takaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Wei Heng

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. 永井祐介

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 古家喜四夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
25. 西田基宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI KEN 高橋 賢

TAKAHASHI Ken 高橋 賢

高橋 賢 タカハシ ケン

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Elucidation of mechanism of ischemia-reperfusion injury using heart-, brain-, and kidney-on-a-chipsPrincipal Investigator

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Elucidation of the mechanism of arrhythmia in myocardial infarction in an organ-on-a-chipPrincipal Investigator

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Elucidation of the mechanism of arrhythmia in cardiac ischemia-reperfusion injury by imaging technologyPrincipal Investigator

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[Book] Mechanobiology: Exploitation for Medical Benefit2017

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[Book] Mechanobiology: Exploitation for Medical Benefit2017

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[Book] Mechanobiology2017

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TAKAHASHI KEN 高橋賢

TAKAHASHI Ken 高橋賢

高橋賢タカハシケン