TANI-ICHI Shizue 谷一靖江

Researcher Number	50432331
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 京都大学, 医学研究科, 特定講師 2016 – 2020: 京都大学, 医学研究科, 助教 2009 – 2015: 京都大学, ウイルス研究所, 助教
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Immunology / Basic Section 49070:Immunology-related / Experimental pathology
Keywords	Principal Investigator 制御性T細胞 / IL-7 / TCR / IL-7レセプター / サイトカイン / 免疫学 / 骨格筋 / 糖尿病 / ２型糖尿病 / 制御性T細胞（Treg） … More / ガンマデルタT細胞 / TCRシグナル / γδT細胞 / ホメオスタシス / γδ T細胞 / インターロイキン7 / T細胞 / サイトカインレセプター / リンパ球 … More Except Principal Investigator サイトカイン / IL-15 / 微小環境 / ストローマ細胞 / 腫瘍免疫 / 自然免疫 / 感染症 / 免疫学 / T細胞 / リンパ組織 / IL-7 / 抗ウイルス免疫応答 / 生理学 / 内科 / 糖質コルチコイド / 適応免疫 / 内分泌系 / 概日リズム / ステロイド / 骨芽細胞 / Bリンパ球 / Tリンパ球 / 自然リンパ球 / NK細胞 / 発生・分化 / 生体分子 / リンパ球 / 免疫組織 / 免疫細胞 / GFP / 胸腺上皮細胞 / NKT細胞 / 胸腺 / 遺伝子改変マウス / インターロイキン7 / γδ T細胞 / 小腸上皮内リンパ球 Less

Investigation of the function of IL-7 in skeletal muscle-residing Tregs and its therapeutic application to sarcopeniaPrincipal Investigator
- Principal Investigator
  
  谷一靖江
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
Control of immune response and tissue homeostasis by novel IL-15-dependent innate lymphocytes
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseases
- Principal Investigator
  
  Ikuta Koichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
Cytokine IL-7-mediated amelioration of insulin resistancePrincipal Investigator
- Principal Investigator
  
  Tani-ichi Shizue
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kyoto University
Control of innate immune cells, chronic inflammation and infection by cytokine-producing immune microenvironment
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
Control of dynamics and function of T cells by glucocorticoids via IL-7 receptor expression
- Principal Investigator
  
  Ikuta Koichi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Requirement of TCR signal for the maintenance of gamma/delta T cells in peripheral tissuePrincipal Investigator
- Principal Investigator
  
  Tani-ichi Shizue
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Distribution and function of IL-15-producing cells in vivo
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Analysis of the peripheral T cell function by using IL-7R conditional knockout micePrincipal Investigator
- Principal Investigator
  
  TANI-ICHI SHIZUE
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Regulation of IL-7R expression in thymocytes and memory T cellsPrincipal Investigator
- Principal Investigator
  
  TANI-ICHI Shizue
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Distribution and function of IL-7-producing cells
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University

[Book] T細胞におけるIL-7レセプターの転写制御と機能Transcriptional regulation and function of IL-7 receptor in T cells :臨床免疫・アレルギー科61(4)2014
- Author(s)
  谷一靖江、原崇裕、生田宏一
- Publisher
  科学評論社
- URL
  http://ci.nii.ac.jp/nrid/9000248200929
- Data Source
  KAKENHI-PROJECT-24790469
[Book] Role of the IL-7 receptor inγδT-cell development from hematopoietic stem cells. In "Hematopoietic Stem Cell Biology". Kondo, M., ed.2009
- Author(s)
  Ikuta, K. and Tani-ichi, S.
- Publisher
  Humana Press Inc
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow2023
- Author(s)
  Abe Shinya、Asahi Takuma、Hara Takahiro、Cui Guangwei、Shimba Akihiro、Tani-ichi Shizue、Yamada Kohei、Miyazaki Kazuko、Miyachi Hitoshi、Kitano Satsuki、Nakamura Naotoshi、Kikuta Junichi、Vandenbon Alexis、Miyazaki Masaki、Yamada Ryo、Ohteki Toshiaki、Ishii Masaru、Sexl Veronika、Nagasawa Takashi、Ikuta Koichi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 9 Pages: 113127-113127
- DOI
  10.1016/j.celrep.2023.113127
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-21K08370, KAKENHI-PROJECT-22K19430, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-23K24152, KAKENHI-PROJECT-23K27425, KAKENHI-PROJECT-23K27426
[Journal Article] Lung group 2 innate lymphoid cells differentially depend on local IL-7 for their distribution, activation, and maintenance in innate and adaptive immunity-mediated airway inflammation2023
- Author(s)
  Takami Daichi、Abe Shinya、Shimba Akihiro、Asahi Takuma、Cui Guangwei、Tani-ichi Shizue、Hara Takahiro、Miyata Keishi、Ikutani Masashi、Takatsu Kiyoshi、Oike Yuichi、Ikuta Koichi
- Journal Title
  
  International Immunology
  
  Volume: 35 Issue: 11 Pages: 513-530
- DOI
  10.1093/intimm/dxad029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-23K27426
[Journal Article] CD45 alleviates airway inflammation and lung fibrosis by limiting expansion and activation of ILC2s2023
- Author(s)
  Cui Guangwei、Shimba Akihiro、Jin Jianshi、Hojo Nozomi、Asahi Takuma、Abe Shinya、Ejima Aki、Okada Shinri、Ohira Keizo、Kato Ryoma、Tani-ichi Shizue、Yamada Ryo、Ebihara Takashi、Shiroguchi Katsuyuki、Ikuta Koichi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 36
- DOI
  10.1073/pnas.2215941120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-21K19368, KAKENHI-PROJECT-23K27426
[Journal Article] Interleukin-7 receptor signaling is crucial for enhancer-dependent TCRd germline transcription mediated through STAT5 recruitment2022
- Author(s)
  Rodriguez-Caparros, A., Tani-ichi, S., Casal, A., Lopez-Ros, J., Sune, C., Ikuta, K., and Hernandez-Munain, C.
- Journal Title
  
  Front. Immunol.
  
  Volume: 13 Pages: 943510-943510
- DOI
  10.3389/fimmu.2022.943510
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03501
[Journal Article] A circulating subset of iNKT cells mediates antitumor and antiviral immunity2022
- Author(s)
  Cui G, Shimba A, et.al
- Journal Title
  
  Science Immunology
  
  Volume: 7 Issue: 76 Pages: 8760-8760
- DOI
  10.1126/sciimmunol.abj8760
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07545, KAKENHI-PROJECT-22K07086, KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-20K21522, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-20K17580, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-21J15058
[Journal Article] Androgens Alleviate Allergic Airway Inflammation by Suppressing Cytokine Production in Th2 Cells2022
- Author(s)
  Ejima Aki、Abe Shinya、Shimba Akihiro、Sato Susumu、Uehata Takuya、Tani-ichi Shizue、Munakata Satoru、Cui Guangwei、Takeuchi Osamu、Hirai Toyohiro、Kato Shigeaki、Ikuta Koichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 209 Issue: 6 Pages: 1083-1094
- DOI
  10.4049/jimmunol.2200294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-20H03501
[Journal Article] Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intra-epithelial lymphocytes in the intestine2019
- Author(s)
  Zhu Yuanbo、Cui Guangwei、Miyauchi Eiji、Nakanishi Yuki、Mukohira Hisa、Shimba Akihiro、Abe Shinya、Tani-ichi Shizue、Hara Takahiro、Nakase Hiroshi、Chiba Tsutomu、Sehara-Fujisawa Atsuko、Seno Hiroshi、Ohno Hiroshi、Ikuta Koichi
- Journal Title
  
  International Immunology
  
  Volume: 32 Issue: 5 Pages: 307-319
- DOI
  10.1093/intimm/dxz082
- NAID
  120006846480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-19K07604, KAKENHI-PROJECT-19K16687, KAKENHI-PROJECT-19K16712, KAKENHI-PROJECT-20K16280, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-18K07958
[Journal Article] Notch signaling controls transcription via the recruitment of RUNX1 and MYB to enhancers during T cell development2019
- Author(s)
  Rodriguez-Caparros, A., Garcia, V., Casal, A, Lopez-Ros, J., Garcia-Mariscal, A., Tani-ichi, S., Ikuta, K., and Hernandez-Munain, C.
- Journal Title
  
  J. Immunol.
  
  Volume: 202 Issue: 8 Pages: 2460-2472
- DOI
  10.4049/jimmunol.1801650
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Journal Article] Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR42018
- Author(s)
  Shimba A, Cui G, Tani-Ichi S, Ogawa M, Abe S, Okazaki F, Kitano S, Miyachi H, Yamada H, Hara T, Yoshikai Y, Nagasawa T, Schütz G, Ikuta K.
- Journal Title
  
  Immunity
  
  Volume: 48 Issue: 2 Pages: 286-298
- DOI
  10.1016/j.immuni.2018.01.004
- NAID
  120006401712
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08835, KAKENHI-PLANNED-16H06496, KAKENHI-PUBLICLY-17H05643, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16K15288, KAKENHI-PROJECT-17K15721
[Journal Article] Thy-1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation2016
- Author(s)
  Shinoda, K., Hirahara, K., Iinuma, T., Ichikawa, T., Suzuki, A., Sugaya, K., Tumes, D. J., Yamamoto, H., Hara, T., Tani-ichi, S., Ikuta, K., Okamoto, Y., and Nakayama, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: ?
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460589
[Journal Article] Thy-1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation2016
- Author(s)
  Shinoda, K., Hirahara, K., Iinuma, T., Ichikawa, T., Suzuki, A. S., Sugaya, K., Tumes, D. J., Yamamoto, H., Hara, T., Tani-ichi, S., Ikuta, K., Okamoto, Y., and Nakayama, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 113 Issue: 20
- DOI
  10.1073/pnas.1512600113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16K15288
[Journal Article] Hematopoietic stem cell niches produce lineage-instructive signals to control multipotent progenitor differentiation2016
- Author(s)
  Gomes, A. C., Hara, T., Lim, V. Y., Herndler-Brandstetter, D., Nevius, E., Sugiyama, T., Tani-ichi, S., Schlenner, S., Richie, E., Rodewald, H., Flavell, R. A., Nagasawa, T., Ikuta, K., and Pereira, J. P.
- Journal Title
  
  Immunity
  
  Volume: 45 Issue: 6 Pages: 1219-1231
- DOI
  10.1016/j.immuni.2016.11.004
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16K08835, KAKENHI-PROJECT-16K15288
[Journal Article] An Enhancer of the IL-7 Receptor α-Chain Locus Controls IL-7 Receptor Expression and Maintenance of Peripheral T Cells.2015
- Author(s)
  Abe A, Tani-ichi S, Shitara S, Cui G, Yamada H, Miyachi H, Kitano S, Hara T, Abe R, Yoshikai Y, Ikuta K.
- Journal Title
  
  J. Immunol.
  
  Volume: 195 Issue: 7 Pages: 3129-3138
- DOI
  10.4049/jimmunol.1302447
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06843, KAKENHI-PUBLICLY-15H01153, KAKENHI-PROJECT-15F15114, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-26860322
[Journal Article] STAT5 Orchestrates Local Epigenetic Changes for Chromatin Accessibility and Rearrangements by Direct Binding to the TCRγ Locus.2015
- Author(s)
  Wagatsuma K, Tani-Ichi S, Liang B, Shitara S, Ishihara K, Abe M, Miyachi H, Kitano S, Hara T, Nanno M, Ishikawa H, Sakimura K, Nakao M, Kimura H, Ikuta K.
- Journal Title
  
  J Immunol.
  
  Volume: 195 Issue: 4 Pages: 1804-14
- DOI
  10.4049/jimmunol.1302456
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-26460572, KAKENHI-PROJECT-15K21083, KAKENHI-PUBLICLY-15H01153, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-26640007, KAKENHI-PROJECT-26860322
[Journal Article] Characterization of the interleukin-15 niche in primary and secondary lymphoid organs in vivo.2014
- Author(s)
  Cui G, Hara T, Simmons S, Wagatsuma K, Abe A, Miyachi H, Kitano S, Ishii M, Tani-ichi S, Ikuta K.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111 Issue: 5 Pages: 1915-1920
- DOI
  10.1073/pnas.1318281111
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-26860322
[Journal Article] Environments of B cell development.2014
- Author(s)
  Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-Ichi S, Ikuta K, Grun J. R, Grutzkau A, Engels N, Wienands J, Yanagisawa Y, Ohnishi K , Melchers F.
- Journal Title
  
  Immunol Lett.
  
  Volume: 157 Issue: 1-2 Pages: 60-63
- DOI
  10.1016/j.imlet.2013.11.011
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] Lymphocyte-stromal cell interaction induces IL-7 expression by interferon regulatory factors.2013
- Author(s)
  Sekai M, Tani-ichi S, Yoneyama M, Fujita T, Kina T, Ikuta K.
- Journal Title
  
  Mol Immunol
  
  Volume: 54 Issue: 3-4 Pages: 378-385
- DOI
  10.1016/j.molimm.2013.01.002
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] B cell progenitors and precursors change their microenvironment in fetal liver during early development.2013
- Author(s)
  Tsuneto M, Tokoyoda K, Kajikhina E, Hauser AE, Hara T, Tani-ichi S, Ikuta K, Melchers F.
- Journal Title
  
  Stem Cells
  
  Volume: 31 Issue: 12 Pages: 2800-2812
- DOI
  10.1002/stem.1421
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] CD49b-dependent estabhshment of T helper cell memory.2013
- Author(s)
  Hanazawa, A., Hayashizaki, K.,Shinoda, K., Yagita, H., Okumura, K., Löhning, M., Hara, T., Tani-ichi, S., Ikuta, K., Eckes, B.,Radbruch, A., Tokoyoda, K, and Nakayama, T.
- Journal Title
  
  Immuno1. Cell Bio1
  
  Volume: 91 Issue: 8 Pages: 524-531
- DOI
  10.1038/icb.2013.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02883, KAKENHI-PROJECT-23390260, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-25860352
[Journal Article] Interleukin-7 receptor controls development and maturation of late stages of thymocyte subpopulations.2013
- Author(s)
  Tani-Ichi, S., Shimba, A., Wagatsuma, K., Miyachi, H., Kitano, S., Imai, K., Hara, T., and Ikuta, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 110 Issue: 2 Pages: 612-617
- DOI
  10.1073/pnas.1219242110
- NAID
  120005241695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659202, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469
[Journal Article] Interleukin-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCRγδ+ intraepithelial lymphocytes.2013
- Author(s)
  Shitara S, Hara T, Liang B, Wagatsuma K, Zuklys S, Hollander GA, Nakase H, Chiba T, Tani-ichi S, Ikuta K.
- Journal Title
  
  J Immunol
  
  Volume: 190 Issue: 12 Pages: 6173-6179
- DOI
  10.4049/jimmunol.1202573
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice2012
- Author(s)
  Hara T, Shitara S, Imai K, Miyachi H, Kitano S, Yao H, Tani-ichi S, Ikuta K
- Journal Title
  
  J. Immunol
  
  Volume: 189(4) Pages: 1577-1584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790469
[Journal Article] Role of hepatocyte-derived IL-7 in maintenance of intrahepatic NKT cells and T cells and development of B cells in fetal liver.2012
- Author(s)
  Liang, B., T. Hara, K. Wagatsuma, J. Zhang, K. Maki, H. Miyachi, S. Kitano, C. Yabe-Nishimura, S. Tani-Ichi, and K. Ikuta
- Journal Title
  
  Journal of Immunology
  
  Volume: 189 Issue: 9 Pages: 4444-4450
- DOI
  10.4049/jimmunol.1201181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659202, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469
[Journal Article] The pre-TCR signal induces transcriptional silencing of the TCRγlocus by reducing the recruitment ofSTAT5 and Runx to transcriptional enhancers2011
- Author(s)
  Tani-ichi, S., Satake, M., and Ikuta, K.
- Journal Title
  
  Int. Immunol
  
  Volume: 23 Pages: 553-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers2011
- Author(s)
  Tani-ichi, S., Satake, M., Ikuta, K.
- Journal Title
  
  Int.Immunol.
  
  Volume: 23 Issue: 9 Pages: 553-563
- DOI
  10.1093/intimm/dxr055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531, KAKENHI-PROJECT-22790460
[Journal Article] Accessibility control of TCR Vγregion by STAT52010
- Author(s)
  Tani-ichi, S., Lee, H.-C., Ye, S.-K., and Ikuta, K.
- Journal Title
  
  Int. Immunol
  
  Volume: 22 Issue: 8 Pages: 693-703
- DOI
  10.1093/intimm/dxq054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531, KAKENHI-PROJECT-22790460
[Journal Article] Accessibility control of TCR Vγ region by STAT52010
- Author(s)
  Tani-ichi, S., Lee, H.-C., Ye, S.-K., Ikuta, K.
- Journal Title
  
  International Immunology
  
  Volume: 22 Pages: 693-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790460
[Journal Article] Accessibility control of TCR Vγ region by STAT52010
- Author(s)
  Tani-ichi, S., Lee, H.-C., Ye, S.-K., Ikuta, K.
- Journal Title
  
  International Immunology
  
  Volume: 22 Pages: 693-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Activation of the mouse T cell receptor γ enhancers by STAT5.2009
- Author(s)
  Tani-ichi, S., et al.
- Journal Title
  
  Int. immunol. 21
  
  Pages: 1079-1088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Activation of the mouse T cellreceptorγenhancers by STAT52009
- Author(s)
  Tani-ichi, S., Satake, M., and Ikuta, K.
- Journal Title
  
  Int. Immunol
  
  Volume: 21 Issue: 9 Pages: 1079-1088
- DOI
  10.1093/intimm/dxp073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] Bone marrow microenvironment for NK cell differentiation and localization2024
- Author(s)
  阿部真也、榛葉旭恒、谷一靖江、長澤丘司、生田宏一
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27426
[Presentation] Lung local IL-7 affect the maintenance, distribution, and activation of ILC2 in allergic airway inflammations2022
- Author(s)
  Daichi Takami, Shinya Abe, Akihiro Shimba, Takuma Asahi, Guangwei Cui, Shizue Tani-ichi, Takahiro Hara, and Koichi Ikuta
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] Function of IL-7Rα in regulatory T cells2019
- Author(s)
  谷一靖江、原崇裕、向平妃沙、生田宏一
- Organizer
  第48回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08999
[Presentation] 制御性T細胞におけるIL-7レセプターの役割2019
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第29回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-19K08999
[Presentation] Intestinal epithelial cell-derived IL-15 supports the homeostasis of intraepithelial lymphocytes2018
- Author(s)
  Zhu, Y., Cui, G., Shimba, A., Abe, S., Hara, T., Tani-ichi, S., and Ikuta, K.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Local IL-15 dependency of liver-resident ILC12018
- Author(s)
  Asahi, T., Shimba, A., Cui, G., Abe, S., Zhu, Y., Ejima, A., Takami, D., Tani-ichi, S., Hara, T., and Ikuta, K.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] CXCL12-expressing bone marrow stromal cells express adiponectin and are targeted by Adipoq-Cre transgene2018
- Author(s)
  Mukohira, H., Hara, T., Tani-ichi, S., and Ikuta, K.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] IL-7Rα signaling upregulates growth hormone signaling-related gene in naive T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  Keystone Symposium: Integrating Metabolism and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Exploring the signals upregulating IL-7Rα expression via NFκB activation in T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Exploring the signals upregulating IL-7Rα expression via NFκB activation in T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Regulation of IL-7 receptor expression by a proximal enhancer2017
- Author(s)
  榛葉旭恒、崔広為、谷一靖江、原崇裕、生田宏一
- Organizer
  KTCC 2017
- Place of Presentation
  芝蘭会館、京都
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Competition between STAT5 and PI3K of the IL-7R modulates T cell and type 2 ILC development in vivo2017
- Author(s)
  Cui, G., Shimba, A., Zhu, Y., Tani-ichi, S., Hara, T., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Competition between STAT5 and PI3K of the IL-7R modulates T cell and type 2 ILC development in vivo2017
- Author(s)
  Cui, G., Shimba, A., Zhu, Y., Tani-ichi, S., Hara, T., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] IL-7Rα signaling upregulates growth hormone signaling-related gene in naive T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  Keystone Symposium: Integrating Metabolism and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Role of glucocorticoids in T cell homeostasis and T cell response2016
- Author(s)
  榛葉旭恒、崔広為、阿部真也、朱媛博、向平妃沙、谷一靖江、原崇裕、生田宏一
- Organizer
  The 23rd East Asia Joint Symposium
- Place of Presentation
  台北、台湾
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Local function of the IL-15 niche in thymus2016
- Author(s)
  崔広為、榛葉旭恒、阿部真也、朱媛博、向平妃沙、谷一靖江、原崇裕、生田宏一
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Role of TCRgamma enhancer Egamma4 for the development and function of gamma delta T cells2016
- Author(s)
  Shizue Tani-ichi and Koichi Ikuta
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  Melbourne, Australia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460572
[Presentation] Characterization of the IL-15 niche in vivo2015
- Author(s)
  Cui, G., Hara, T., Simmons, S., Ishii, M., Tani-ichi, S., Ikuta, K.
- Organizer
  The 6th FIMSA Congress
- Place of Presentation
  Singapore
- Year and Date
  2015-07-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Regulation of IL-7R expression in dendritic cells2015
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] STAT5 and PI3K signals of the IL-7R play differential roles in T cell development and homeostasis revealed by novel IL-7Rα mutant mice2015
- Author(s)
  崔広為、榛葉旭恒、谷一靖江、小川真、阿部真也、原崇裕、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Differential roles of IL-7 and IL-2 receptor signals in lymphocyte differentiation and development revealed by IL-7Rα/IL-2Rβ chimera knock-in mice2015
- Author(s)
  榛葉旭恒、谷一靖江、増田喬子、崔広為、小川真、阿部真也、原崇裕、河本宏、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] 末梢組織でのガンマデルタT細胞維持におけるTCRシグナルの必要性2014
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第24回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Differential roles of IL-7 and IL-2 receptor signals in lymphocyte development and maintenance revealed by IL-7Rα/IL-2Rβ chimera knock-in mice2014
- Author(s)
  榛葉旭恒、谷一靖江、増田喬子、原崇裕、河本宏、生田宏一
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Visualizing the immune microenvironment by reporter mice2013
- Author(s)
  Ikuta, K., Cui, G., Shitara, S., Liang, B., Tani-ichi, S., and Hara, T.
- Organizer
  The 20th East Asia Joint Symposium on Global Medical Science for the 22th Century
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Visualization of the immune microenvironment by reporter mice2013
- Author(s)
  Ikuta, K., Cui, G., Shitara, S., Liang, B., Tani-ichi, S., and Hara, T.
- Organizer
  The 6th International Workshop of Kyoto T Cell Conference 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Visualization and characterization of IL-7- and IL-15-expressing cells in vivo2013
- Author(s)
  Hara, T., Cui, G., Shitara, S., Tani-ichi, S. and Ikuta, K.
- Organizer
  The 6th International Workshop of Kyoto T Cell Conference 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Identification and characterization of the IL-15-expressing cells in vivo2013
- Author(s)
  Cui, G., Hara, T., Simmons, S., Wagatsuma, K., Tani-ichi, S., Ishii, M., and Ikuta, K.
- Organizer
  The 20th East Asia Joint Symposium on Global Medical Science for the 22th Century
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Role of a TCRγenhancer,Eγ4,in differentiation and function ofγδT cell subsets2013
- Author(s)
  TANI-ICHI Shizue,WAGATSUMA Keisuke and IKUTA Koichi
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2013-12-11
- Data Source
  KAKENHI-PROJECT-24790469
[Presentation] STAT5によるTCR遺伝子再編成の制御機構2012
- Author(s)
  我妻慶祐、谷一靖江、梁涼霧、設楽宗一朗、生田宏一
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-24790469
[Presentation] NFBとAP-1シグナルはCNSを介してIL-7Rの発現レベルを制御する2012
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-24790469
[Presentation] NF-kB and AP-1 signals control IL-7R expression in T cells through CNS2012
- Author(s)
  TANI-ICHI Shizue and IKUTA Koichi
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24790469
[Presentation] Enhancers control locus -wide accessibility of the TCRγlocus in vivo2012
- Author(s)
  WAGATSUMA Keisuke,TANI-ICHI Shizue and IKUTA Koichi
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24790469
[Presentation] Function of IL-7R in the late stage of T cell development2011
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] IL-7Rα鎖遺伝子の近位エンハンサーは末梢T細胞のIL-7Rの発現を制御する2011
- Author(s)
  阿部昌史、谷一靖江、生田宏一
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] T細胞分化の後期におけるIL-7Rの役割2011
- Author(s)
  谷一靖江
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都平安ホテル(京都府)
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] T細胞分化の後期におけるIL-7Rの機能2011
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第21回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] Function of IL-7 receptor in the late stage of T cell development2011
- Author(s)
  谷一靖江
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] 肝細胞が産生するIL-7は肝臓でのリンパ球の分化と維持を制御する2011
- Author(s)
  梁冰霏、原崇裕、我妻慶祐、設楽宗一朗、谷一靖江、生田宏一
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] A conserved enhancer element controls the expression of IL-7 receptorα-chain in peripheral T cells2011
- Author(s)
  阿部昌史、谷一靖江、生田宏一
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] Local function of IL-7 produced by thymic and epidermal epithelial cells2010
- Author(s)
  Liang, B., Hara, T., Tani-ichi, S., Ikuta, K.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] IL-7R signal controls differentiation of CD8 T cells and maintenance of preripheral T cells2010
- Author(s)
  A.Abe, S.Tani-ichi, K.Ikuta
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] Molecular mechanism of TCRγsilencing2010
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] Local function of IL-7produced by thymic and epidermal epithelial cells2010
- Author(s)
  Liang, B., Hara, T., Tani-ichi, S., and Ikuta, K.
- Organizer
  The 14^<th> International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] Distribution of IL-7-expressing cells in lymphoid organs2010
- Author(s)
  Hara, T., Tani-ichi, S., Ikuta, K.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] IL-7Rsignal controls differentiation of CD8 Tcells and maintenance of peripheral T cells2010
- Author(s)
  Abe, A., Tani-ichi, S., and Ikuta, K.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22790460
[Presentation] Distribution of IL-7-expressing organs. International Congress of Immunology2010
- Author(s)
  Hara, T., Tani-ichi, S., and Ikuta, K
- Organizer
  The 14^<th> International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] リンパ組織におけるIL-7産生細胞の分布と機能2009
- Author(s)
  生田宏一、原崇裕、梁冰霏、谷一靖江
- Organizer
  第32回日本分子生物学会年会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] 胸線上皮細胞が産生するIL-7の局所的役割2009
- Author(s)
  生田宏一、原崇裕、梁冰霏、谷一靖江
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] リンパ組織におけるIL-7産生細胞の分布と機能2009
- Author(s)
  生田宏一、原崇裕、梁冰霏、谷一靖江
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] Role of a TCRγ enhancer, Eγ4, in differentiation and function of γδ T cell subsets.
- Author(s)
  Shizue TANI-ICHI, Keisuke WAGATSUMA, and Koichi IKUTA
- Organizer
  第42回　日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24790469
[Presentation] 末梢組織でのガンマデルタT細胞維持におけるTCRシグナルの必要性
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第24回 Kyoto T cell Conference
- Place of Presentation
  京都平安ホテル
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26460572
[Presentation] NFκBとAP-1シグナルはCNSを介してIL-7Rの発現レベルを制御する
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第22回 Kyoto T Cell Conference
- Place of Presentation
  京都和順会館
- Data Source
  KAKENHI-PROJECT-24790469
[Presentation] NF-κB and AP-1 signals control IL-7R expression in T cells through CNS
- Author(s)
  Shizue Tani-ichi and Koichi Ikuta
- Organizer
  第41回　日本免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場・神戸国際展示場・神戸ポートピアホテル
- Data Source
  KAKENHI-PROJECT-24790469

1. IKUTA Koichi (90193177)

# of Collaborated Projects: 6 results

# of Collaborated Products: 43 results
2. HARA Takahiro (90512301)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
3. 榛葉旭恒 (30812242)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. 崔广為 (70791276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 阿部真也 (70972678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. IMAI Kumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. CUI Guangwei

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. MUKOHIRA Hisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. Zhu Yuanbo

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. OGAWA Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGASAWA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 宮内栄治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 安部良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 宮地均

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

TANI-ICHI Shizue 谷一 靖江

Research Projects

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Co-Researchers

Investigation of the function of IL-7 in skeletal muscle-residing Tregs and its therapeutic application to sarcopeniaPrincipal Investigator

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Control of immune response and tissue homeostasis by novel IL-15-dependent innate lymphocytes

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IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseases

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Cytokine IL-7-mediated amelioration of insulin resistancePrincipal Investigator

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Control of innate immune cells, chronic inflammation and infection by cytokine-producing immune microenvironment

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Control of dynamics and function of T cells by glucocorticoids via IL-7 receptor expression

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Requirement of TCR signal for the maintenance of gamma/delta T cells in peripheral tissuePrincipal Investigator

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Distribution and function of IL-15-producing cells in vivo

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Analysis of the peripheral T cell function by using IL-7R conditional knockout micePrincipal Investigator

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Regulation of IL-7R expression in thymocytes and memory T cellsPrincipal Investigator

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Distribution and function of IL-7-producing cells

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[Book] T細胞におけるIL-7レセプターの転写制御と機能Transcriptional regulation and function of IL-7 receptor in T cells :臨床免疫・アレルギー科61(4)2014

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[Book] Role of the IL-7 receptor inγδT-cell development from hematopoietic stem cells. In "Hematopoietic Stem Cell Biology". Kondo, M., ed.2009

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[Journal Article] Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow2023

TANI-ICHI Shizue 谷一靖江