OKUYAMA Hiroaki 奥山裕照

… Alternative Names

奥山裕照オクヤマヒロアキ

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Researcher Number	50432373
Affiliation (based on the past Project Information) *help	2016: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 総括研究員 2016: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), 研究所, 研究員 2015: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, その他 2014 – 2015: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所, 研究員 2013 – 2014: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所, 総括研究員 … More 2013: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所病理学部門, 総括研究員 2012: 大阪府立成人病センター(研究所), 研究所, 統括研究員 2011 – 2012: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所, 研究員 2011: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所, 総括研究員 2009 – 2010: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究員 2007: Kyoto University, 医学研究科, 助教 2006: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Tumor biology / Tumor biology / Pathological medical chemistry Except Principal Investigator Anesthesiology / Tumor biology / Experimental pathology
Keywords	Principal Investigator Src / 3次元培養 / 肝転移 / dynamin / src / 極性 / ３次元培養 / 大腸癌 / HIF / MYC … More / 大腸がん / 初代培養 / dormancy / 低酸素 / がん細胞の特性 / 骨髄間質細胞 / 細胞療法 / 肝不全 / 骨髓間質細胞 / チオレドキシン … More Except Principal Investigator スフェロイド / 転移 / がん / RNA-Seq / HIF-1 / CTOS / 悪性度 / がん細胞 / 麻酔薬 / ERBBシグナル / WNTシグナル / 幹細胞性 / 再生 / 破壊 / 培養 / 癌 / HIF / VEGF / 浸潤 / 血管新生 Less

Investigation of effects of anesthetics on phenotype and gene expression of cancer cells with CTOS method
- Principal Investigator
  
  IWAI Teppai
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Kansai Medical University
初代３次元培養ヒト大腸癌における癌細胞の極性転換機構とがん転移への関与の解明Principal Investigator
- Principal Investigator
  
  奥山裕照
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
Malignant conversion of cancer cells by disruption and remodeling of cancer cell-clusters in newly developed primary culture system
- Principal Investigator
  
  INOUE Masahiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
Hypoxia-induced dormancy identified by a novel 3D culture method of primary cancerPrincipal Investigator
- Principal Investigator
  
  OKUYAMA Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
Mechanism of inducing invasive phenotype after VEGF inhibition
- Principal Investigator
  
  INOUE Masahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
チオレドキシンを高発現する骨髄間質細胞を用いた劇症肝炎・肝不全治療Principal Investigator
- Principal Investigator
  
  奥山裕照
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University

All 2016 2015 2014 2013 2012 2011 2010 2007 2006 Other

All Journal Article Presentation

[Journal Article] Dynamic Change of Polarity in Primary Cultured Spheroids of Human Colorectal Adenocarcinoma and Its Role in Metastasis2016
- Author(s)
  Okuyama H, Kondo J, Sato Y, Endo H, Nakajima A, Piulats JM, Tomita Y, Fujiwara T, Itoh Y, Mizoguchi A, Ohue M, Inoue M
- Journal Title
  
  Am J Pathol
  
  Volume: 186 Issue: 4 Pages: 899-911
- DOI
  10.1016/j.ajpath.2015.12.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15577, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-26430138
[Journal Article] High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids.2015
- Author(s)
  Yoshida T, Okuyama H, Nakayama M, Endo H, Nonomura N, Nishimura K, Inoue M
- Journal Title
  
  Cancer science
  
  Volume: 106 Issue: 1 Pages: 69-77
- DOI
  10.1111/cas.12567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300333, KAKENHI-PLANNED-26111005
[Journal Article] Dormancy of Cancer Cells with Suppression of AKT Activity Contributes to Survival in Chronic Hypoxia.2014
- Author(s)
  Endo H, Okuyama H, Ohue M, Inoue M
- Journal Title
  
  PloS one
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300333
[Journal Article] Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix.2014
- Author(s)
  Nakajima A, Endo H, Okuyama H, Kiyohara Y, Kimura T, Kamiura S, Hiraoka M, Inoue M.
- Journal Title
  
  Int J Cancer
  
  Volume: - Issue: 12 Pages: 2949-2960
- DOI
  10.1002/ijc.29349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300333, KAKENHI-PROJECT-25461937, KAKENHI-PLANNED-26111005
[Journal Article] Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation2013
- Author(s)
  Endo H, Okami J, Okuyama H, Kumagai T, Uchida J, Kondo J, Takehara T, Nishizawa Y, Imamura F, Higashiyama M, Inoue M
- Journal Title
  
  J Thorac Oncol
  
  Volume: 8 Pages: 131-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300333
[Journal Article] Involvement of Heregulin/HER3 in the Primary Culture of Human Urothelial Cancer2013
- Author(s)
  Hiroaki Okuyama
- Journal Title
  
  Journal of Urology
  
  Volume: Epub ahead of print Issue: 1 Pages: 302-310
- DOI
  10.1016/j.juro.2012.12.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791240, KAKENHI-PROJECT-23501282, KAKENHI-PROJECT-24300333
[Journal Article] Involvement of Heregulin/HER3 in the Primary Culture of Human Urothelial Cancer2013
- Author(s)
  Hiroaki Okuyama, Takahiro Yoshida, Hiroko Endo, Masashi Nakayama, Norio Nonomura, Kazuo Nishimura and Masahiro Inoue
- Journal Title
  
  Journal of Urology
  
  Volume: Vol 190 Pages: 302-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501282
[Journal Article] 低酸素環境における遺伝子制御2012
- Author(s)
  奥山裕照,井上正宏
- Journal Title
  
  THE LUNG-perspectives
  
  Volume: 20(1) Pages: 69-74
- Data Source
  KAKENHI-PROJECT-21590459
[Journal Article] Cellular hypoxia of pancreatic β-cells due to high levels of oxygen consumption for insulin secretion in vitro2011
- Author(s)
  Sato Y., et al
- Journal Title
  
  J Biol.Chem.
  
  Volume: 286 Issue: 14 Pages: 12524-12532
- DOI
  10.1074/jbc.m110.194738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-21590459, KAKENHI-PROJECT-21591184
[Journal Article] 低酸素環境とCancer Dormancy2011
- Author(s)
  奥山裕照,井上正宏
- Journal Title
  
  癌と化学療法
  
  Volume: 38(10) Pages: 1559-1564
- Data Source
  KAKENHI-PROJECT-21590459
[Journal Article] Cell-surface thioredoxin-1: possible involvement in thiol-mediated leukocyte-endothelial cell interaction through lipid rafts.2007
- Author(s)
  Hara T, Kondo N, Nakamura H, Okuyama H, Hoshino Y, Yodoi J
- Journal Title
  
  Antioxidant Redox Signaling 9
  
  Pages: 1427-1437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890089
[Journal Article] Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia.2007
- Author(s)
  Bosch-Marce M, Okuyama H, Wesley JB, Semenza GL., et. al.
- Journal Title
  
  Circulation Research 101
  
  Pages: 1310-1318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890089
[Journal Article] Recombinant human thioredoxin-1 becomes oxidized in circulation and suppresses bleomycin-induced neutrophil recruitment in the rat airway.2007
- Author(s)
  Nakamura T, Hoshino Y, Yamada A, Teratani A, Furukawa S, Okuyama H, Yodoi J, Nakamura H.
- Journal Title
  
  Free Radical Research 41
  
  Pages: 1089-1098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890089
[Journal Article] Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B2006
- Author(s)
  Krishnamachary B, Zagzag D, Nagasawa H, Rainey K, Okuyama H, Baek JH, Semenza GL.
- Journal Title
  
  Cancer Research 66
  
  Pages: 2725-2731
- Data Source
  KAKENHI-PROJECT-18890089
[Journal Article] Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 12006
- Author(s)
  Okuyama H, Krishnamachary B, Zhou YF, Nagasawa H, Bosch-Marce M, Semenza GL.
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 15554-15563
- Data Source
  KAKENHI-PROJECT-18890089
[Journal Article] Spontaneous transformation of cultured mouse bone marrow-derived stromal cells.2006
- Author(s)
  Zhou YF, Bosch-Marce M, Okuyama H, Krishnamachary B, Kimura H, Zhang L, Huso DL, Semenza GL
- Journal Title
  
  Cancer Research 66
  
  Pages: 10849-10854
- Data Source
  KAKENHI-PROJECT-18890089
[Presentation] ３次元癌細胞初代培養法を用いた感受性試験により明らかとなったセツキシマブ感受性の異なるKRAS変異大腸癌の2群2016
- Author(s)
  多代尚広、奥山裕照、萩原健、JM Piulats、遠藤洋子、河田健二、蘆田康子、大植雅之、坂井義治、井上正宏
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26430138
[Presentation] Distinct types of cetuximab resistant KRAS mutant of colorectal cancer revealed by an integrated sensitivity assay2015
- Author(s)
  Tashiro T, Okuyama H, Sasaki K, JM Piulats, Kawada K, Komada T, Ohue M, Sakai Y, Inoue M
- Organizer
  平成26年度「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  琵琶湖ホテル（大津市）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] A monoclonal antibody to the surface of cancer-derived spheroid inhibits adhesion and migration to collagen2015
- Author(s)
  Yumi Sato, Hiroaki Tateno, Hiroaki Okuyama, Masahiro Inoue
- Organizer
  日本癌学会シンポジウム／共同利用・共同研究拠点シンポジウム
- Place of Presentation
  石川県立音楽堂（金沢市）
- Year and Date
  2015-01-21
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 膀胱癌腔内播種におけるΔNp63αの関与2015
- Author(s)
  吉田栄宏, 奥山裕照, 中山雅志, 西村和郎, 井上正宏, 野々村祝夫
- Organizer
  第24回泌尿器科分子・細胞研究会
- Place of Presentation
  JRタワーホール＆カンファレンス（東京都）
- Year and Date
  2015-02-28
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] Inactive status of cancer cells with suppression of AKT activity contributes to survival in chronic hypoxia2014
- Author(s)
  Masahiro Inoue, Hiroaki Okuyama, Hiroko Endo, Masayuki Ohue
- Organizer
  American Association for Cancer Research(AACR) Annual Meeting 　2014
- Place of Presentation
  SanDiego Convention Center(USA）
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 尿路上皮癌細胞塊の細胞外基質への接着はdelta N p63の速やかな分解を誘発する2014
- Author(s)
  吉田栄宏,　奥山裕照,　中山雅志,　西村和郎,　野々村祝夫,　井上正宏
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 膀胱内注入療法に用いられる高濃度の抗癌剤は膀胱癌細胞のミトコンドリア膜電位を低下しネクローシスを誘導する2014
- Author(s)
  吉田栄宏, 奥山裕照, 中山雅志, 西村和郎, 井上正宏, 野々村祝夫
- Organizer
  第102回日本泌尿器科学会総会
- Place of Presentation
  神戸国際会議場・神戸国際展示場・神戸ポートピアホテル（神戸市）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] High-dose chemotherapeutics used in intravesical therapy induce mitochondrial dysfunction followed by necrosis-like cell death in bladder cancer cells2014
- Author(s)
  Takahiro Yoshida, Hiroaki Okuyama, Masashi Nakayama, Kazuo Nishimura, Masahiro Inoue, Norio Nonomura
- Organizer
  American Urological Association Annual Meeting 2014
- Place of Presentation
  Orange country convention center (Orando USA)
- Year and Date
  2014-05-18
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 新規３次元癌細胞初代培養（CTOS）法を用いた大腸癌に対するセツキシマブ感受性試験の検討2014
- Author(s)
  多代尚広, 奥山　裕照, 佐々木一雄, JM Piulats, 河田　健二, 駒田徹, 大植　雅之, 坂井　義治, 井上　正宏
- Organizer
  文部科学省新学術領域研究・がん支援　化学療法基盤支援活動第3回シンポジウム
- Place of Presentation
  万国津梁館（名護市）
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 新規３次元癌細胞初代培養(CTOS)法を用いた大腸癌に対するセツキシマブ感受性試験の検討2014
- Author(s)
  多代尚広,　奥山裕照,　佐々木一雄,　JM Piulats,　河田健二,　駒田徹,　大植雅之,　坂井義治,　井上正宏
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館(京都市）
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 肺がん初代培養細胞における低酸素下休眠状態の誘導メカニズム2014
- Author(s)
  遠藤洋子, 奥山裕照, 井上正宏
- Organizer
  第12回がんとハイポキシア研究会
- Place of Presentation
  ホテルマリターレ創世佐賀（佐賀市）
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] CTOS法による子宮頸部小細胞がん・腺がん混合腫瘍のクロナリティーの解析2014
- Author(s)
  久保田　哲, 中嶋綾, 清原裕美子, 遠藤洋子, 奥山裕照, 井上正宏
- Organizer
  平成26年度文科省科研費新学術領域研究「がん研究分野の特性等を踏まえた支援活動」がん若手研究者ワークショップ
- Place of Presentation
  蓼科グランドホテル滝の湯（茅野市）
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] ヒト分化型大腸がんの初代培養スフェロイドにおける極性転換2014
- Author(s)
  奥山裕照,　遠藤洋子,　井上正宏
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 新規3次元癌細胞初代培養(CTOS)法を用いた大腸癌に対するセツキシマブ感受性試験の検討2014
- Author(s)
  多代尚広,　奥山裕照,　佐々木一雄,　Piulats JM,　遠藤洋子,　河田健二,　駒田　徹,　大植雅之,　坂井義治,　井上正宏
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 大腸癌での極性転換と転移での役割2014
- Author(s)
  奥山裕照, 井上正宏
- Organizer
  第2回細胞凝集研究会
- Place of Presentation
  アクロス福岡
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 腫瘍由来スフェロイド表面を認識する細胞接着、浸潤機能を阻害するモノクローナル抗体の作製2014
- Author(s)
  佐藤友美, 井上正宏,　奥山裕照
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] Rapid decrease of ATP followed by necrosis-like cell death in bladder cancer cells after exposure to high-dose chemotherapeutics used in intravesical therapy2014
- Author(s)
  Takahiro Yoshida, Hiroaki Okuyama, Masashi Nakayama, Kazuo Nishimura, Norio Nonomura, Masahiro Inoue
- Organizer
  American Association for Cancer Research(AACR) Annual Meeting 　2014
- Place of Presentation
  SanDiego Convention Center(USA）
- Year and Date
  2014-04-07
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 腫瘍由来初代培養スフェロイドを用いたがん細胞表面認識モノクローナル抗体の作製と機能解析2014
- Author(s)
  佐藤友美, 井上正宏, 奥山裕照
- Organizer
  第23回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢ニューグランドホテル（金沢市）
- Year and Date
  2014-07-10
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 肺がん初代培養細胞を用いた患者個人のALK阻害剤耐性機構の評価2014
- Author(s)
  遠藤洋子,　西野和美,　熊谷　融, 奥山裕照,　今村文生,　井上正宏
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] An in vitro model of intravesical chemotherapy for bladder cancer using cancer tissue-originated2012
- Author(s)
  Yoshida T, Okuyama H, Nakayama M, Nishimura K, Nonomura N, Inoue M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] Influence of disruption on tissue remodeling in cancer tissue-originated spheroids(CTOS)2012
- Author(s)
  Piulats R. Jose M, Okuyama H, Endo H, Inoue M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] Analysis of radiosensitivity mechanisms in cervical cencer CTOS2012
- Author(s)
  Nakajima A, Endo H, Okuyama H, Hiraoka M. Inoue M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 癌細胞初代培養におけるheregulinの重要性2012
- Author(s)
  奥山裕照, 井上正宏
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  オリエンタルホテル広島
- Year and Date
  2012-07-13
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] Diverse response to heregulin and lapatinib between cancer tissue-originated spheroids from human urological cancer2012
- Author(s)
  Okuyama H, Yoshida T, Endo H, Nakayama M, Nishimura K, Nonomura N, Inoue M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] Hif-1αis necessary for invasive phenotype after angiogenisis inhibition2011
- Author(s)
  Takaaki Takeda, Hiraoaki Okuyama, Shuhei Tomita, Yasuko Nishizawa, Masahiro Inoue
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  北海道大学
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21590459
[Presentation] Hif-1α is necessary for invasive phenotype after angiogenisis inhibition2011
- Author(s)
  Takaaki Takeda, Hiraoaki Okuyama, Shuhei Tomita, Yasuko Nishizawa, Masahiro Inoue
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21590459
[Presentation] HIF-1alpha is necessary for changes of adhesion molecules and invasive phenotype attex angiogenesis(血管新生を阻害すると生じる接着分子の変化と浸潤形質にHIF-1αは必須である)2010
- Author(s)
  Takaaki Takeda, Hiraoaki Okuyama, Yasuko Nishizawa, Masahiro Inoue
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  リーガロイヤルホテル大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590459
[Presentation] HIF-1alpha is necessary for changes of adhesion molecules and invasive phenotype after angiogenesis2010
- Author(s)
  Takaaki Takeda, Hiraoaki Okuyama, Yasuko Nishizawa, Masahiro Inoue
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  リーガロイヤルホテル大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590459
[Presentation] Thioredoxin binding protein 2 regulates Concanavalin A-induced hepatitis through hepatic NKT cells2007
- Author(s)
  Hiroaki Okuyama, Aoi Son, Hiroshi Masutani, Junji Yodoi, and Hajime Nakamura
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京、グランドプリンスホテル新高輪
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18890089
[Presentation] HIF-1αは放射線抵抗性の初代がん培養細胞において放射線照射後に発現が上昇する
- Author(s)
  中嶋　綾,　遠藤洋子,　奥山裕照,　平岡真寛,　井上正宏
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] Neuregulin1/HER3シグナルは肺腺がん初代培養細胞の増殖を促進する
- Author(s)
  遠藤洋子,　岡見次郎,　奥山裕照,　東山聖彦,　井上正宏
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 子宮頸部小細胞癌-初代培養細胞における放射線照射後のHIF-1α発現上昇は放射線抵抗性に関与する
- Author(s)
  中嶋　綾, 遠藤洋子, 奥山裕照, 平岡真寛, 井上正宏
- Organizer
  第11回がんとハイポキシア研究会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-24300333
[Presentation] 癌細胞初代培養系（CTOS）における低酸素による休眠状態の誘導
- Author(s)
  遠藤洋子, 奥山裕照, 井上正宏
- Organizer
  第11回がんとハイポキシア研究会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-24300333

1. INOUE Masahiro (10342990)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
2. ENDO Hiroko (20359300)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. IWAI Teppai (90440966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 広田喜一 (00283606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OKUYAMA Hiroaki 奥山 裕照

奥山 裕照 オクヤマ ヒロアキ

Research Projects

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Co-Researchers

Investigation of effects of anesthetics on phenotype and gene expression of cancer cells with CTOS method

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初代３次元培養ヒト大腸癌における癌細胞の極性転換機構とがん転移への関与の解明Principal Investigator

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Malignant conversion of cancer cells by disruption and remodeling of cancer cell-clusters in newly developed primary culture system

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Hypoxia-induced dormancy identified by a novel 3D culture method of primary cancerPrincipal Investigator

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Mechanism of inducing invasive phenotype after VEGF inhibition

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チオレドキシンを高発現する骨髄間質細胞を用いた劇症肝炎・肝不全治療Principal Investigator

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[Journal Article] Dynamic Change of Polarity in Primary Cultured Spheroids of Human Colorectal Adenocarcinoma and Its Role in Metastasis2016

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[Journal Article] High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids.2015

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[Journal Article] Dormancy of Cancer Cells with Suppression of AKT Activity Contributes to Survival in Chronic Hypoxia.2014

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[Journal Article] Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix.2014

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[Journal Article] Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation2013

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[Journal Article] Involvement of Heregulin/HER3 in the Primary Culture of Human Urothelial Cancer2013

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[Journal Article] Involvement of Heregulin/HER3 in the Primary Culture of Human Urothelial Cancer2013

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[Journal Article] 低酸素環境における遺伝子制御2012

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[Journal Article] Cellular hypoxia of pancreatic β-cells due to high levels of oxygen consumption for insulin secretion in vitro2011

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OKUYAMA Hiroaki 奥山裕照

奥山裕照オクヤマヒロアキ