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YUKI Morizane  森實 祐基

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… Alternative Names

森實 祐基  モリザネ ユウキ

森実 祐基  モリザネ ユウキ

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Researcher Number 50432646
Other IDs
Affiliation (Current) 2025: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 岡山大学, 医歯薬学域, 教授
2020: 岡山大学, 医歯薬学総合研究科, 教授
2018 – 2019: 岡山大学, 医歯薬学総合研究科, 准教授
2013 – 2017: 岡山大学, 大学病院, 講師
2013: 岡山大学, 附属病院, 講師 … More
2012: 岡山大学, 医歯(薬)学総合研究科, 助教
2008: 岡山大, 医学部・歯学部附属病院, 助教
2008: 岡山大学, 医歯薬学総合研究科, 助教
2007: 岡山大学, 医学部・歯学部附属病院, 助教
2007: Okayama University, 大学院・医歯薬学総合研究科, 助教 Less
Review Section/Research Field
Principal Investigator
Basic Section 56060:Ophthalmology-related / Ophthalmology
Except Principal Investigator
Ophthalmology / Basic Section 56060:Ophthalmology-related
Keywords
Principal Investigator
網膜色素上皮細胞 / 網膜 / 加齢黄斑変性 / 手術 / 硝子体 / カリウム / レーバー先天盲 / カリウムチャネル / ルテイン / キサントフィル … More / AMPK / X線回折 / クリスタリン / 白内障 / 水晶体 … More
Except Principal Investigator
加齢黄斑変性 / 未熟児網膜症 / 緑内障 / 上皮間葉転換 / 微小重力 / 網膜 / 遺伝子治療 / ボルナウイルス / アクアポリン / メカニカルストレス / 黄斑浮腫 / 終末糖化産物 / 糖尿病網膜症 / 治療 / AMPK / マイクロチップ / アロステリック効果 / 酸素分圧 / 周産期 / 胎児循環 / 胎児ヘモグロビン / 血管新生 / 酸素親和度 / ヘモグロビン / 細胞外マトリックス / 水晶体 / 眼球形成 / 眼球発達 / 血管アポトーシス / 瞳孔膜 Less
  • Research Projects

    (15 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (25 People)
  •  微小重力環境を用いた加齢黄斑変性の新規治療薬開発

    • Principal Investigator
      細川 海音
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Okayama University
  •  緑内障の手術成績に関与する新規バイオマーカーの開発と個別化医療の確立

    • Principal Investigator
      藤原 美幸
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Okayama University
  •  網膜硝子体界面疾患における膜形成の病態の多面的解析Principal Investigator

    • Principal Investigator
      森實 祐基
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Okayama University
  •  難治性網膜疾患の遺伝子治療を目的としたボルナウイルスベクターの開発

    • Principal Investigator
      塩出 雄亮
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Okayama University
  •  Investigation of the function of potassium channel Kir7.1 in retinal pigment epithelial cellsPrincipal Investigator

    • Principal Investigator
      Morizane Yuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Okayama University
  •  Investigation of the role of longevity genes in the retina using genome editing technologyPrincipal Investigator

    • Principal Investigator
      Morizane Yuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Okayama University
  •  A Novel Therapeutic Strategy for Macular Edema Targeting Aquaporins.

    • Principal Investigator
      Shiraga Fumio
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  Metabolism and function of xanthophyll in the retinaPrincipal Investigator

    • Principal Investigator
      Morizane Yuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  Novel therapeutic strategy targeting advanced glycation end product

    • Principal Investigator
      Shiraga Fumio
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  Inhibition of RPE senescence by AMPK activationPrincipal Investigator

    • Principal Investigator
      YUKI Morizane
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  眼球発達期の網膜血管形成におけるAMPキナーゼの役割:未熟児網膜症の新治療戦略

    • Principal Investigator
      塚本 真啓
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  Anti-aging of the retinal pigment epithelial cells by activation of AMP kinase

    • Principal Investigator
      KIMURA Shuhei
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  生体血管膜モデルを用いた血管新生・消退機構の統合的解析

    • Principal Investigator
      高畠 隆
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University
  •  未熟児網膜症におけるヘモグロビン変換の関与

    • Principal Investigator
      毛利 聡
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Kawasaki Medical School
      Okayama University
  •  発達期水晶体の透明性獲得機構の解明:SPring-8X線回折による統合的解析Principal Investigator

    • Principal Investigator
      森實 祐基
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Okayama University

All 2024 2023 2020 2013 2007 Other

All Journal Article Presentation

  • [Journal Article] KCNJ13 Gene Deletion Impairs Cell Alignment and Phagocytosis in Retinal Pigment Epithelium Derived from Human-Induced Pluripotent Stem Cells2020

    • Author(s)
      Kanzaki Yuki、Fujita Hirofumi、Sato Keita、Hosokawa Mio、Matsumae Hiroshi、Shiraga Fumio、Morizane Yuki、Ohuchi Hideyo
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 61 Issue: 5 Pages: 38-38

    • DOI

      10.1167/iovs.61.5.38

    • NAID

      120006869576

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09625, KAKENHI-PROJECT-20K08885, KAKENHI-PROJECT-19K18878, KAKENHI-PROJECT-18K09410
  • [Presentation] Protrusion of KCNJ13 Gene Knockout Retinal Pigment Epithelium Due to Oxidative Stress-Induced Cell Death.2024

    • Author(s)
      Yuki Kanzaki
    • Organizer
      第128回日本眼科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K09700
  • [Presentation] 網膜色素上皮細胞におけるレーバー先天黒内障16型原因遺伝子KCNJ13のノックアウトは酸化ストレス感受性を高め細胞死を誘導する2023

    • Author(s)
      藤田洋史, 神崎勇希, 佐藤恵太, 細川海音, 松前洋, 森實祐基, 大内淑代
    • Organizer
      第76回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09700
  • [Presentation] カリウムチャネル遺伝子KCNJ13ノックアウト網膜色素上皮では酸化ストレスにより細胞死を生じる2023

    • Author(s)
      大内淑代, 神崎勇希, 藤田洋史, 佐藤恵太, 細川海音, 松前洋, 森實祐基
    • Organizer
      第63回日本先天異常学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09700
  • [Presentation] KCNJ13 gene deletion impairs phagocytosis in retinal pigment epithelium derived from human-induced pluripotent stem cells.2020

    • Author(s)
      Yuki Kanzaki; Hirofumi Fujita; Keita Sato; Mio Hosokawa; Hiroshi Matsumae; Fumio Shiraga; Yuki Morizane; Hideyo Ohuchi
    • Organizer
      ARVO Annual Meeting 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09410
  • [Presentation] ARPE-19の細胞増殖におけるAMP依存性キナーゼの役割2013

    • Author(s)
      塚本真啓、森實祐基、木村修平、米澤朋子、小阪淳、白神史雄
    • Organizer
      日本眼科学会
    • Place of Presentation
      東京
    • Year and Date
      2013-04-04
    • Data Source
      KAKENHI-PROJECT-24890133
  • [Presentation] マウス網膜色素上皮の細胞の細胞遊走におけるAMP依存性キナーゼの役割2013

    • Author(s)
      森實祐基、竹内喉雄、鈴木潤、吉村武、塚本真啓、木村修平、Viollet Benoit、白神史雄、Miller Joan、Vavvas Demetrios
    • Organizer
      日本眼科学会
    • Place of Presentation
      東京
    • Year and Date
      2013-04-04
    • Data Source
      KAKENHI-PROJECT-24890133
  • [Presentation] Hemodynamic effects of replacement of RBC with small-size liposomal hemoglobin on pulmonary hypertensive rat2007

    • Author(s)
      Satoshi Mohri, Yuki Katanosaka, Akira Yamada, and Keiji Naruse
    • Organizer
      European society of cardiology, annual congress 2007
    • Place of Presentation
      ウィーン オーストリア
    • Year and Date
      2007-09-02
    • Data Source
      KAKENHI-PROJECT-19659451
  • [Presentation] Suppressive effect of AMPK on epithelial-mesenchymal transition of retinal pigment epithelial cells

    • Author(s)
      的場亮、森實祐基
    • Organizer
      アメリカ眼科学会(ARVO)
    • Place of Presentation
      デンバー、米国
    • Year and Date
      2015-05-03 – 2015-05-07
    • Data Source
      KAKENHI-PROJECT-24592630
  • [Presentation] AMPK活性化による網膜色素上皮細胞の上皮間葉転換の抑制

    • Author(s)
      的場亮、森實祐基
    • Organizer
      日本眼科学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-04-15 – 2015-04-19
    • Data Source
      KAKENHI-PROJECT-24592630
  • [Presentation] 早期老化誘導および急性酸化ストレスが網膜色素上皮細胞のMMP産生に及ぼす影響の比較

    • Author(s)
      荒木亮一、森實祐基
    • Organizer
      日本眼科学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-04-15 – 2015-04-19
    • Data Source
      KAKENHI-PROJECT-24592630
  • 1.  YONEZAWA Tomoko (30304299)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  大内 淑代 (00253229)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 3.  Shiraga Fumio (50187530)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  成瀬 恵治 (40252233)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  毛利 聡 (00294413)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  塩出 雄亮 (20711097)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  本田 知之 (80402676)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Matoba Ryo
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KOSAKA Jun (40243216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KIMURA Shuhei (90628710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  高畠 隆 (50379781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  大月 洋 (70093672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  片野坂 友紀 (60432639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  宮坂 武寛 (60308195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  塚本 真啓 (00625717)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  西堀 正洋 (50135943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  菅原 満 (60332467)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  且原 真木 (00211847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  細川 海音 (00711053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  藤原 美幸 (30739800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  神崎 勇希 (50972741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  谷岡 真樹 (60573045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  Hirano Masayuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  Takahashi Kosuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  FUJITA Hirofumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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