Uehara Ikuno 上原郁野

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UEHARA Ikuno 上原郁野

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Researcher Number	50434139
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2022: 日本医科大学, 先端医学研究所, 助教 2009: 日本医科大学, 老人病研究所, 助教 2009: 老人病研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Biological Sciences
Keywords	Principal Investigator cancer stem cell / sphere / Cancer stem cell / Ivermectin / metastasis / IFN-alpha / beta / IFN alpha / IFN beta / oGlcMAc / Sox2 … More / IFN / cGAS-STING / がん幹細胞 / IFN-α/β / cGAS-STING経路 … More Except Principal Investigator Hedgehogシグナル / 細胞周期制御 / Aurora-A / GLUT3 / 癌遺伝子 / 足場非依存性増殖 / β / Hedgehog signal / B / IKKα / NF-KB / Mdm2 / Hedeho sinal / Stat3 / IL-6 / 発癌 / P53 / O-GlcNAc修飾 / グルコーストランスポーター / NF-κB / グルコース代謝 / p53 / 癌抑制 / 癌化 Less

Analysis of tumor suppression mechanism by antiparasitic drug Ivermectin targeting cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  上原郁野
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nippon Medical School
The role of cGAS-STING pathway in cancer maintenance and metastasisPrincipal Investigator
- Principal Investigator
  
  Uehara Ikuno
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nippon Medical School
Analysis of the gene transcriptional network system regulated by nuclear tumor suppressive factors
- Principal Investigator
  
  TANAKA Nobuyuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nippon Medical School

All 2022 2021 2020 2019 2010 2009 2008

All Journal Article Presentation

[Journal Article] 2-Deoxy-D-glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation2022
- Author(s)
  Uehara I., Kajita M., Tanimura A., Hida S.,Onda M., Naito Z., Taki S., Tanaka N.
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 10 Issue: 2 Pages: 1-16
- DOI
  10.1002/prp2.940
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07759, KAKENHI-PROJECT-21K06613, KAKENHI-PROJECT-20K07017
[Journal Article] Interleukin 6 enhances glycolysis through expression of the glycolytic enzymes hexokinase2and6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-3.2010
- Author(s)
  Ando, M., Uehara, I., Kogure, K., Asano, Y., Nakajima, W., Abe, Y., Kawauchi, K., Tanaka, N.
- Journal Title
  
  J Nippon Med Sch 77
  
  Pages: 97-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054039
[Journal Article] 5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis.2008
- Author(s)
  Yagi, S., Oda-Sato, E., Uehara, I., Asano, Y., Nakajima, W., Takeshita, T., Tanaka, N.
- Journal Title
  
  Cancer Invest 26
  
  Pages: 680-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] がん幹細胞に対する抗寄生虫薬Ivermectinの効果2021
- Author(s)
  上原　郁野、梶田　満子、田中　信之
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07759
[Presentation] Role of typeI interferon induced by cGAS-STING pathway in cancer stem cell maintenance.2020
- Author(s)
  上原　郁野、田中　信之
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07759
[Presentation] cGAS-STING経路を介して産生されるI型インターフェロンのがん細胞における役割2019
- Author(s)
  上原郁野、梶田満子、田中信之
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07759
[Presentation] 大腸炎誘発癌におけるグルコース代謝亢進の役割の解析.2009
- Author(s)
  上原郁野、安藤大、小暮佳代、浅野由ミ、川内敬子、田中信之
- Organizer
  第32会日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] 大腸炎誘発癌におけるグルコース代謝亢進の役割の解析2009
- Author(s)
  上原郁野
- Organizer
  第32会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-17054039
[Presentation] p53のネガティブレギュレーターとして機能するp53新規誘導遺伝子の同定第31回日本分子生物学会年会2008
- Author(s)
  小野寺恵吾、川内敬子、佐藤(織田)恵理、上原郁野、田中信之
- Organizer
  第81回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17054039

1. TANAKA Nobuyuki (80222115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. ABE Yoshinori (00386153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. NAKAJIMA Wataru (40557500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. SATO Eri (90339440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. KAWAUTI Keiko (40434138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. TOBIUME Kei (40350037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Uehara Ikuno 上原 郁野

UEHARA Ikuno 上原 郁野

Research Projects

Research Products

Co-Researchers

Analysis of tumor suppression mechanism by antiparasitic drug Ivermectin targeting cancer stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of cGAS-STING pathway in cancer maintenance and metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the gene transcriptional network system regulated by nuclear tumor suppressive factors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 2-Deoxy-D-glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interleukin 6 enhances glycolysis through expression of the glycolytic enzymes hexokinase2and6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-3.2010

Author(s)

Journal Title

Data Source

[Journal Article] 5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis.2008

Author(s)

Journal Title

Data Source

[Presentation] がん幹細胞に対する抗寄生虫薬Ivermectinの効果2021

Author(s)

Organizer

Data Source

[Presentation] Role of typeI interferon induced by cGAS-STING pathway in cancer stem cell maintenance.2020

Author(s)

Organizer

Data Source

[Presentation] cGAS-STING経路を介して産生されるI型インターフェロンのがん細胞における役割2019

Author(s)

Organizer

Data Source

[Presentation] 大腸炎誘発癌におけるグルコース代謝亢進の役割の解析.2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 大腸炎誘発癌におけるグルコース代謝亢進の役割の解析2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] p53のネガティブレギュレーターとして機能するp53新規誘導遺伝子の同定第31回日本分子生物学会年会2008

Author(s)

Organizer

Place of Presentation

Data Source

Uehara Ikuno 上原郁野

UEHARA Ikuno 上原郁野