KOSAKA CarolinaAndrea 小坂カロリナアンドレア

… Alternative Names

YOSHIDA Carolina Andrea 吉田カロリナアンドレア

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Researcher Number	50437828
Affiliation (Current)	2025: 浜松医科大学, 医学部, 特任研究員
Affiliation (based on the past Project Information) *help	2012: 長崎大学, 大学院・医歯薬学総合研究科, 助教 2010: Nagasaki University, 大学院・医歯薬総合研究科, 助教 2007 – 2010: Nagasaki University, 大学院・医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Mechanobiology / Morphological basic dentistry
Keywords	Principal Investigator Galnt3 / 骨代謝 / 骨格 / リン代謝 / 骨 / skeletal development / bone / cartilage / skeletal develonment / knock out mouse / 軟代謝学 … More Except Principal Investigator … More Runx2 / ノックアウト / 細胞・組織 / Fbxo / 発生・分化 / 組織 / 細胞 / 骨量 / 遺伝子 / メカニカルストレス / 骨形成 / ノックアウトマウス / 膜性骨化 / 軟骨内骨化 / 軟骨細胞 / 骨芽細胞 / 転写因子 / コンディショナルノックアウトマウス / Cbfb / 口腔解剖学(含組織学・発生学) Less

Functional analysis of a mechanical stress responsible geneFbxo32 on bone volume regulation
- Principal Investigator
  
  IZUMI Shinichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mechanobiology
- Research Institution
  Nagasaki University
GALNT3 functions in phosphate homeostasis and bone biologyPrincipal Investigator
- Principal Investigator
  
  YOSHIDA CarolinaAndrea
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagasaki University
Elucidation of the mechanism of skeletal development using Runx2 and Cbfb conditional knockout mice
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
EIucidation of GaInt3 functions in skeletal development and metabolismPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Carolina Andrea
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagasaki University

All 2012 2011 2009 2008 2007

All Journal Article Presentation

[Journal Article] es bone loss at unloading by promoting osteoclastogenesis2012
- Author(s)
  Wang Y, Liu W, Masuyama R, Fukuyama R, Ito M, Zhang Q, Komori H, Murakami T, Moriishi T, Miyazaki T, Kitazawa R, Yoshida CA, Kawai Y, Izumi S, and Komori T
- Journal Title
  
  Bone
  
  Volume: 50 Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22616006
[Journal Article] Early onset of Runx2 expression causes craniosynostosis, ectopic bone formation, and limb defects2011
- Author(s)
  Maeno T, Moriishi T, Yoshida C, Komori H, Kanatani N, Izumi S, Takaoka K, and Komori T
- Journal Title
  
  Bone
  
  Volume: 49 Pages: 673-682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22616006
[Journal Article] Akt regulates skeletal development through GSK3, mTOR, and FoxOs2009
- Author(s)
  O Rokutanda S, Fujita T, Kanatani N, Yoshida CA, Komori H, Liu W, Mizuno A, Komori T
- Journal Title
  
  Dev Biol Vol.328, No.1
  
  Pages: 78-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791404
[Journal Article] Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells2008
- Author(s)
  Tanaka T, Sato H, Doi H, Yoshida CA, Shimizu T, Matsui H, Yamazaki M, Akiyama H, Kawai-Kowase K, Iso T, Komori T, Arai M, Kurabayashi M
- Journal Title
  
  Mol Cell Biol 28
  
  Pages: 1147-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390465
[Journal Article] Double deficiency of tetraspanins CD9 and CD81 Alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice2008
- Author(s)
  Takeda Y, He P, Tachibana I, Zhou B, Miyado K, Kaneko H, Suzuki M, Minami S, Iwasaki T, Goya S, Kijima T, Kumagai T, Yoshida M, Osaki T, Komori T, Mekada E, Kawase I
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 26089-26097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390465
[Journal Article] Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells2008
- Author(s)
  Tanaka T, Sato H, Doi H, Yoshida CA, Shimizu T, Matsui H, Yamazaki M, Akiyama H, Kawai-Kowase K, I so T, Komori T, Arai M, Kurabayashi M
- Journal Title
  
  Mol Cell Biol 28
  
  Pages: 1147-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791039
[Journal Article] Inhibition of terminal differentiation of odontoblasts and their transdifferentiation into osteoblasts in Runx2 transgenic mice2008
- Author(s)
  Miyazaki T, Kanatani N, Rokutanda S,Yoshida C, Toyosawa S, Nakamura R, Takada S, Komori T
- Journal Title
  
  Arch Histol Cytol 71
  
  Pages: 131-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791039
[Journal Article] Inhibition of terminal differentiation of odontoblasts and their transdifferentiation into osteoblasts in Runx2 transgenic mice2008
- Author(s)
  Miyazaki T, Kanatani N, Rokutanda S, Yoshida C, Toyosawa S, Nakamura R, Takada S, Komori T
- Journal Title
  
  Arch Histol Cytol 71
  
  Pages: 131-146
- NAID
  10025095779
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390465
[Journal Article] Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency2007
- Author(s)
  Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T,Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T
- Journal Title
  
  Dev Dyn 236
  
  Pages: 1876-1890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791039
[Journal Article] Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency2007
- Author(s)
  Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T, Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T
- Journal Title
  
  Dev Dyn 236
  
  Pages: 1876-1890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Akt Regerates Skeletal Development Through GSK3, mTOR, and FoxOs2008
- Author(s)
  Rokutanda S, Fujita T, Kanatani N, Yoshida CA, Mizuno A, Komori T
- Organizer
  30th Annual Meeting(American society for Bone and Mineral Research)
- Place of Presentation
  カナダ(Montreal)
- Data Source
  KAKENHI-PROJECT-19791039
[Presentation] Akt Regerates Skeletal Development Through GSK3, mTOR, and FoxOs2008
- Author(s)
  Rokutanda S, Fu j ita T, Kanatani N, Yoshida CA, Mizuno A, Komori T
- Organizer
  30th Annual Meeting (American society for Bone and Mineral Research)
- Place of Presentation
  Montreal
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Runx2 gain of function in mesenchymal cells enhanced bone fomation but inhibited cartilage fomation and limb development(ミニシンポジウム)2008
- Author(s)
  Yoshida CA, Maeno T, Kanatani N, Izumi S, Fujita T, Yamana K, Takaoka K, Komori T
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Runx2 gain of function in mesenchymal cells enhanced bone fomation but inhibited cartilage fomation and limb development (ミニシンポジウム)2008
- Author(s)
  Carolina A. Yoshida
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Runx2 gain of function in mesenchymal cells enhanced bone fomation butinhibited cartilage fomation and limb development(ミニシンポジウム)2008
- Author(s)
  Carolina A. Yoshida
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19791039
[Presentation] Runx2 gain of function in mesenchymal cells enhanced bone fomation but inhibited cartilage fomation and limb developmentミニシンポジウム2008
- Author(s)
  Yoshida CA, Maeno T, Kanatani N, Izumi S, Fujita T, Yamana K, Takaoka K, Komori T
- Organizer
  第26回日本代謝学会
- Place of Presentation
  大
- Data Source
  KAKENHI-PROJECT-19791039
[Presentation] Over-expression of Runx2 in mesenchymal cells enhanced bone formation but inhibited cartilage formation and limb development2007
- Author(s)
  Yoshida CA, Maeno T, Kanatani N, Fujita T, Izumi S, Komori T
- Organizer
  29th Annual Meeting(American society for Bone and Mineral Research)
- Place of Presentation
  Honolulu, (USA)
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Runx2 functions during postnatal bone development2007
- Author(s)
  吉田カロリナアンドレア
- Organizer
  日本解剖学会第63回九州支部学術集会
- Place of Presentation
  長崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19791039
[Presentation] Runx2 functions during postnatal bone development2007
- Author(s)
  吉田カロリーナ、宮崎敏博、中村康平、藤田隆司、金谷直子、森石武史、小守壽文
- Organizer
  日本解剖学会第63回九州支部学術集会
- Place of Presentation
  長崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Runx2 functions during postnatal bone development2007
- Author(s)
  吉田カロリナアンドレア
- Organizer
  日本解剖学会第63回九州支蔀学術集会
- Place of Presentation
  長崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] The regulation of chondrocyte proliferation, function, and differentation by AKT signaling pathways(ポスター)2007
- Author(s)
  Fu j ita T, Rokutanda S, Kanatani N, Yoshida C, Komori T
- Organizer
  29th Annual Meeting(American society for Bone and Mineral Research)
- Place of Presentation
  Honolulu, (USA)
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Over-expression of Runx2 in mesenchymal cells enhanced bone formation but inhibited cartilage formation and limb development2007
- Author(s)
  Yoshida CA, Maeno T, Kanatani N, FujitaT, Izumi S, Komori T
- Organizer
  29th Annual Meeting(American society for Bone and Mineral Research)
- Place of Presentation
  Honolulu, (USA)
- Data Source
  KAKENHI-PROJECT-19791039
[Presentation] The regulation of chondrocyte proliferation, function, and differentation by AKT signaling pathways2007
- Author(s)
  Fujita T, Rokutanda S, Kanatani N,Yoshida C, Komori T
- Organizer
  29th Annual Meeting(American society for Bone and Mineral Research)
- Place of Presentation
  Honolulu, (USA)
- Data Source
  KAKENHI-PROJECT-19791039
[Presentation] Coll-Bcl-2トランスジェニックマウスにおける歯牙組織の解析2007
- Author(s)
  江口俊子, 宮崎敏博, 森石武史, 金谷直子, 北浦英樹, 吉田教明, 小守壽文
- Organizer
  日本解剖学会第63回九州支部学術集会
- Place of Presentation
  長崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Over-expression of Runx2 in mesenchymal cells enhanced bone formation but inhibited cartilage formation and limb development.2007
- Author(s)
  吉田カロリナアンドレア
- Organizer
  29th Annual Meeting (ASBMR)
- Place of Presentation
  ホノルル
- Data Source
  KAKENHI-PROJECT-19791039
[Presentation] Over-expression of Runx2 in mesenchymal cells enhanced bone formation but inhibited cartilage formation and limb development.2007
- Author(s)
  吉田カロリナアンドレア
- Organizer
  29th Annual Meeting(ASBMR)
- Place of Presentation
  ホノルル
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] The regulation of chondrocyte proliferation, function, and differentation by AKT signaling pathways2007
- Author(s)
  Fujita T, Rokutanda S, Kanatani N, Yoshida C, Komori T
- Organizer
  29th Annual Meeting(American society for Bone and Mineral Research)
- Place of Presentation
  Honolulu, (USA)
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Runx2 functions during postnatal bone development2007
- Author(s)
  吉田カロリーナ、宮崎敏博、中村康平、藤田司、金谷直子、森石武史、小守壽文
- Organizer
  日本解剖学会第63回九州支部学術会
- Place of Presentation
  崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19791039

1. KOMORI Toshihisa (00252677)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. IZUMI Shinichi (40264246)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. MORIISHI Takeshi (20380983)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. ITO Masako (10193517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. FUKUYAMA Ryo (20389117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. MIYAZAKI Toshihiro (10174161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. NAKAYAMA Koji (80150473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KITAURA Hideki (60295087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 金谷直子 (10380982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results

KOSAKA CarolinaAndrea 小坂 カロリナアンドレア

YOSHIDA Carolina Andrea 吉田 カロリナアンドレア

Research Projects

Research Products

Co-Researchers

Functional analysis of a mechanical stress responsible geneFbxo32 on bone volume regulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GALNT3 functions in phosphate homeostasis and bone biologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of skeletal development using Runx2 and Cbfb conditional knockout mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EIucidation of GaInt3 functions in skeletal development and metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] es bone loss at unloading by promoting osteoclastogenesis2012

Author(s)

Journal Title

Data Source

[Journal Article] Early onset of Runx2 expression causes craniosynostosis, ectopic bone formation, and limb defects2011

Author(s)

Journal Title

Data Source

[Journal Article] Akt regulates skeletal development through GSK3, mTOR, and FoxOs2009

Author(s)

Journal Title

Data Source

[Journal Article] Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells2008

Author(s)

Journal Title

Data Source

[Journal Article] Double deficiency of tetraspanins CD9 and CD81 Alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice2008

Author(s)

Journal Title

Data Source

[Journal Article] Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells2008

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of terminal differentiation of odontoblasts and their transdifferentiation into osteoblasts in Runx2 transgenic mice2008

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of terminal differentiation of odontoblasts and their transdifferentiation into osteoblasts in Runx2 transgenic mice2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency2007

Author(s)

Journal Title

Data Source

[Journal Article] Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency2007

Author(s)

Journal Title

Data Source

[Presentation] Akt Regerates Skeletal Development Through GSK3, mTOR, and FoxOs2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Akt Regerates Skeletal Development Through GSK3, mTOR, and FoxOs2008

Author(s)

Organizer

Place of Presentation

Data Source

KOSAKA CarolinaAndrea 小坂カロリナアンドレア

YOSHIDA Carolina Andrea 吉田カロリナアンドレア