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Terai Hideki  寺井 秀樹

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寺井 秀樹  テライ ヒデキ

TERAI Hideki  寺井 秀樹

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Researcher Number 50445293
Affiliation (Current) 2019: 北里大学, 北里研究所病院, 医長
Affiliation (based on the past Project Information) *help 2018: 北里大学, 北里研究所病院, 医長
2014: 慶應義塾大学, 医学部, 共同研究員
2012 – 2013: 慶應義塾大学, 医学部, 助教
2011 – 2012: 慶應義塾大学, 医学部, 特任助教
2010: 慶應義塾大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related
Except Principal Investigator
Respiratory organ internal medicine
Keywords
Principal Investigator
EGFR-TKI / DNAメチル化 / 肺癌 / 薬剤耐性 / イレッサ / ゲフィチニブ / 獲得耐性 / FGF2 / FGFR1 / FGFR … More / EGFR-TKI耐性化 / エピジェネティクス / epigenetics / drug persister / CRISPR screening / drug resistance / lung cancer … More
Except Principal Investigator
非小細胞肺癌 / 網羅的解析 / pathway signature解析 / fibroblast growth factor-9 / microRNA / exon array / 融合遺伝子 / FGF / 腺癌 / 扁平上皮癌 / Exon array / 染色体転座 / pathway signature / PI3K Less
  • Research Projects

    (4 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (17 People)
  •  CRISPRスクリーニングを用いた根治性の高い肺癌分子標的治療薬の探索Principal InvestigatorOngoing

    • Principal Investigator
      寺井 秀樹
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Kitasato University
  •  網羅的遺伝子解析手法を用いたゲフィチニブ耐性化機序の解明Principal Investigator

    • Principal Investigator
      寺井 秀樹
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Keio University
  •  Investigation of the mechanism of gefitinib resistance by comprehensive genetic analysisPrincipal Investigator

    • Principal Investigator
      TERAI Hideki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Keio University
  •  Screening of fusion genes in non-small cell lung cancer

    • Principal Investigator
      SOEJIMA Kenzo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Keio University

All 2017 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the inhibition of DCLK12017

    • Author(s)
      Matsushita, K., Tamura, M., Tanaka, N., Tomonaga, T., Matsubara, H., Shimada, H., Levens, D., He, L., Liu, J., Yoshida, M., and Nomura, F
    • Journal Title

      Molecular Cancerh Research

      Volume: 11 Pages: 354-362

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21228003, KAKENHI-PROJECT-23591891, KAKENHI-PROJECT-23592470, KAKENHI-PROJECT-24790822, KAKENHI-PROJECT-25430096, KAKENHI-PROJECT-26670549, KAKENHI-PROJECT-26701005, KAKENHI-PROJECT-16K09590, KAKENHI-PROJECT-16K10539
  • [Journal Article] Kenzo Soejima, Hiroyuki Yasuda, et al. Activation of the FGF2-FGFR1 Autocrine Pathway. A Novel Mechanism of Acquired Resistance to Gefitinib in NSCLC2013

    • Author(s)
      Terai H, Soejima K, Yasuda H, et al
    • Journal Title

      Mol Cancer Resr

      Volume: March 27, 2013 Pages: 759-67

    • DOI
      10.1158/1541-7786.mcr-12-0652
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590870, KAKENHI-PROJECT-23501311, KAKENHI-PROJECT-24790822
  • [Journal Article] Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma2013

    • Author(s)
      Hamamoto J, Soejima K, Yoda S, Naoki K, Nakayama S, Satomi R, Terai H, Ikemura S, Sato T, Yasuda H, Hayashi Y, Sakamoto M, Takebayashi T, Betsuyaku T
    • Journal Title

      Mol Med Rep

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Journal Article] The PCR-Invader method (structure-specific 5' nuclease based method), a sensitive method for detecting EGFR gene mutations in lung cancer specimens ; comparison with direct sequencing2011

    • Author(s)
      Naoki K, Soejima K, Okamoto H, Hamamoto J, Hida N, Nakachi I, Yasuda H, Nakayama S, Yoda S, Satomi R, Ikemura S, Terai H, Sato T, Watanabe K
    • Journal Title

      Int J ClinOncol

      Volume: 16 Pages: 335-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Activation of FGF2-FGFR1 pathway in EGFR-mutant lung cancer cell line with long-term gefitinib exposure2013

    • Author(s)
      Terai H, Soejima K, Naoki K, Yasuda H, Satomi R, Nakayama S, Yoda S, Ikemura S, Sato T, Ishioka K, Arai D, Ohgino K, Hamamoto J, Betsuyaku T
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      ワシントン(アメリカ)
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Kenzo Soejima, Katsuhiko Naoki et al. Activation of FGF2-FGFR1 pathway in EGFR-mutant lung cancer cell line with long-term gefitinib exposure2013

    • Author(s)
      Hideki Terai
    • Organizer
      103th AACR annual meeting
    • Place of Presentation
      Washington, DC.
    • Data Source
      KAKENHI-PROJECT-24790822
  • [Presentation] FGF9 overexpression promotes tumorigenic potential of non-small cell lung cancer (NSCLC) cells and is associated with poor prognosis in NSCLC2013

    • Author(s)
      Ishioka K, Soejima K, Yasuda H, Ohgino K, Arai D, Kuroda A, Tani T, Sato T, Terai H, Ikemura S, Yoda S, Hamamoto J, Naoki K, Betsuyaku T
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      ワシントン(アメリカ)
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Activation of FGF2-FGFR1 pathway in EGFR-mutant lung cancer cell line with long-term gefitinib exposure.2013

    • Author(s)
      H. Terai, K. Soejima, K. Naoki, H. Yasuda, R. Satomi, S. Nakayama, S.Yoda, S. Ikemura, T. Sato, K. Ishioka, D. Arai, K. Ohgino, J. Hamamoto, T. Betsuyaku
    • Organizer
      2013 AACR annual meeting
    • Place of Presentation
      Washington, DC, USA
    • Data Source
      KAKENHI-PROJECT-24790822
  • [Presentation] Activation of FGF2-FGFR1 pathway in EGFR-mutant lung cancer cell line with long-term gefitinib exposure.2013

    • Author(s)
      H. Terai, K. Soejima, K. Naoki, et al.
    • Organizer
      103th AACR Annual Meeting
    • Place of Presentation
      Washington, DC.
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] 肺癌におけるTFPI-2のメチル化によるTMPRSS4の過剰発現と癌化2012

    • Author(s)
      浜本純子,副島研造,安田浩之,荒井大輔,石岡宏太,池村辰之介,寺井秀樹,猶木克彦,別役智子
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] FGF9 (fibroblast growth factor 9) 発現肺癌における臨床および遺伝子発現に関する検討2012

    • Author(s)
      120. 扇野圭子,副島研造,荒井大輔,石岡宏太,池村辰之介,寺井秀樹,浜本純子,猶木克彦,別役智子
    • Organizer
      日本臨床腫瘍学会総会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Kenzo Soejima, Katsuhiko Naoki, etal. Activation of FGF2-FGFR1 pathway in EGFR-mutant lung cancer cell line with long-term gefitinib exposure.2012

    • Author(s)
      Hideki Terai
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24790822
  • [Presentation] Activation of FGF2-FGFR1 pathway in EGFR-mutant lung cancer cell line with long-term gefitinib exposure.2012

    • Author(s)
      寺井秀樹、副島研造、猶木克彦、安田浩之、池村辰之介、佐藤崇、荒井大輔、石岡宏太、扇野圭子、濱本純子、別役智子
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌・ホテルロイトン札幌
    • Data Source
      KAKENHI-PROJECT-24790822
  • [Presentation] 肺癌患者における気道上皮被覆液のプロテオーム解析2011

    • Author(s)
      寺井秀樹、副島研造、渡辺真純、猶木克彦、安田浩之、里見良輔、中山荘平、依田聡、池村辰之介、佐藤崇、諸澤麻衣子、浅野浩一郎
    • Organizer
      第51回日本呼吸器学会学術講演会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2011-04-23
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Analysis of aberrant DNA methylation and expression of corresponding mRNA in EGFR-TKI-sensitive lung cancer cell line with long-term gefitinib exposure.2011

    • Author(s)
      H. Terai, K. Soejima, K. Naoki, et al.
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] 肺癌患者の気道上皮被覆液を用いたプロテオーム解析.2011

    • Author(s)
      寺井秀樹, 副島研造, 渡辺真純
    • Organizer
      第34回日本呼吸器内視鏡学会総会
    • Place of Presentation
      浜松
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Analysis of aberrant DNA methylation and expression of corre sponding mRNA in EGFR-TKI-sensitive lung cancer cell line with long-term gefitinib exposure2011

    • Author(s)
      H.Terai, K Soejima, K.Naoki, R.Satomi, S.Nakayama, S.Yoda, S.Ikemura, T.Sato, J.Hamamoto, K.Asano, T.Betsuyaku
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Expression of fibroblast growth factor-9 is associated with poor prognosis of resected non-small cell lung cancer patients2011

    • Author(s)
      Ohgino K, Soejima K, Arai D, Ishioka K, Terai H, Ikemura S, Sato T, Yoda S, Hamamoto J, Naoki K, Betsuyaku T
    • Organizer
      American Association for Cancer Resereach
    • Place of Presentation
      米国、シカゴ
    • Year and Date
      2011-04-03
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma.2011

    • Author(s)
      Junko Hamamoto, Hideki Terai, Katsuhiko Naoki, Takashi Sato, Kenzo Soejima.
    • Organizer
      American Association for Cancer Resereach
    • Place of Presentation
      米国、オーランド
    • Year and Date
      2011-04-06
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma2011

    • Author(s)
      Hamamoto J, Yoda S, Naoki K, Nakayama S, Satomi R, Terai H, Ikemura S, SatoT, Izumi Y, Kawamura M, Nomori H, Hayashi Y, Sakamoto M, Takebayashi T, Soejima K
    • Organizer
      American Association for Cancer Resereach
    • Place of Presentation
      米国、オーランド
    • Year and Date
      2011-04-06
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] 肺癌患者における気道上皮被覆液のプロテオーム解析.2011

    • Author(s)
      寺井秀樹、副島研造、渡辺真純
    • Organizer
      第51回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590870
  • [Presentation] Activation of FGF2-FGFR1 pathway in EGFR-mutant lung cancer cell line with long-term gefitinib exposure.

    • Author(s)
      Hideki Terai
    • Organizer
      2013 104th AACR Annual Meeting
    • Place of Presentation
      Washington D. C. Convention Center
    • Data Source
      KAKENHI-PROJECT-24790822
  • [Presentation] Aberrant DNA methylation and expression of mRNA in EGFR-mutant lung cancer cell line with long-term exposure to gefitinib

    • Author(s)
      Hideki Terai
    • Organizer
      104th AACR Annual Meeting
    • Place of Presentation
      San Diego
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26860616
  • [Presentation] Aberrant DNA methylation and expression of mRNA in EGFR-mutant lung cancer cell line with long-term exposure to gefitinib

    • Author(s)
      Hideki Terai
    • Organizer
      2014 105th AACR Annual Meeting
    • Place of Presentation
      San Diego Convention Center
    • Data Source
      KAKENHI-PROJECT-24790822
  • 1.  SOEJIMA Kenzo (30236145)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 16 results
  • 2.  HAMAMOTO Junko (40570239)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 3.  NAOKI Katsuhiko (40265806)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 4.  SATO Takashi (20464836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 5.  KAWAMURA Masafumi (70169770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  KAWAMOTO Yoshiyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  SASAKI Yasutsuna
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  YAMAOKA Toshimitsu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  OHMORI Tohru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  IKEMURA Shinnosuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  吉田 稔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  松下 一之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  佐藤 守
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  野村 文夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  宮本 新吾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  柴田 淳史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  荒田 悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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