TOMITA Takeo 富田武郎

Researcher Number	50447364
Affiliation (based on the past Project Information) *help	2021 – 2022: 東京大学, 大学院農学生命科学研究科(農学部), 特任准教授 2020: 東京大学, 生物生産工学研究センター, 特任准教授 2007 – 2019: The University of Tokyo, 生物生産工学研究センター, 助教
Review Section/Research Field	Principal Investigator Applied biochemistry / Basic Section 38020:Applied microbiology-related / Applied microbiology Except Principal Investigator Applied microbiology
Keywords	Principal Investigator グルタミン酸脱水素酵素 / ロイシン / アロステリック調節 / 好熱菌 / アミノ酸代謝調節 / タンパク質間相互作用 / グローバル調節 / 活性調節機構 / 分裂酵母 / 立体構造解析 … More / 炭素・窒素代謝調節 / 環境応答 / 活性調節 / トリプトファン生合成 / アミノ酸シグナル応答 / アミノ酸代謝 / 結晶構造解析 / 高度好熱菌 / アミノ酸シグナル / 転写調節 / シグナル伝達 / 生体調節因子 / 遺伝子発現調節 / Corynebacterium glutamicum / リジン生合成 / アスパラギン酸キナーゼ … More Except Principal Investigator キャリアタンパク質 / 構造生物学 / 微生物 / 放線菌 / 結晶構造解析 / 生合成 / アルギニン生合成 / リジン生合成 / クエン酸回路 / ロイシン / アルギニン / リジン / 分子進化 / マレイマイシン / 構造解析 / 二次代謝産物 / アミノ酸 / アミノ基キャリアタンパク質 / 生物活性物質 / 二次代謝 / 遺伝子 / 発現制御 / 酵素 / 応用微生物 / バイオテクノロジー / 結晶構造 / 古細菌 / 好熱性細菌 / 進化 / アミノ酸生合成 / 好熱菌 / 二次代謝産物生合成 / 天然物化学 / 二次代謝生合成 / アスパラギン酸キナーゼ / ホモクエン酸合成酵素 / フィードバック阻害 / X線結晶構造解析 / 機能分化 / 超好熱性古細菌 / ロイシン生合成 / 微生物酵素 Less

Exploration and biochemical characterization of novel regulatory mechanisms of bacterial glutamate dehydrogenasesPrincipal Investigator
- Principal Investigator
  
  富田武郎
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  The University of Tokyo
Studies on mechanisms of biosynthesis of biomolecules via amino-group carrier protein and expansion of structural diversity of secondary metabolites
- Principal Investigator
  
  Nishiyama Makoto
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Elucidation of structures and functions of metabolic enzymes of lysine and related compounds and their molecular evolution
- Principal Investigator
  
  西山真
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Molecular mechanism of amino acid signal transduction system in thermophilic bacteriumPrincipal Investigator
- Principal Investigator
  
  Tomita Takeo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  The University of Tokyo
Elucidation of mechanisms of biomaterial conversion mediated by amino group-modifying carrier protein and application
- Principal Investigator
  
  NISHIYAMA MAKOTO
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
リジン生合成および関連一次代謝系酵素群の機能および分子進化の解析
- Principal Investigator
  
  西山真
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Functional analysis and molecular basis of leucine as a biological regulatorPrincipal Investigator
- Principal Investigator
  
  TOMITA Takeo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  The University of Tokyo
Mechanism of leucine signaling of Thermus thermophilusPrincipal Investigator
- Principal Investigator
  
  TOMITA Takeo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  The University of Tokyo
Structural biology for elucidation of lysine biosynthesis and its regulatory mechanisms
- Principal Investigator
  
  NISHIYAMA Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Analysis of regulatory mechanism of aspartate kinasePrincipal Investigator
- Principal Investigator
  
  TOMITA Takeo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo

[Book] 化学2012
- Author(s)
  富田武郎、西山真
- Total Pages
  2
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-22780084
[Journal Article] Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius2021
- Author(s)
  Suzuki, T., Tomita, T., Hirayama, K., Suzuki, M., Kuzuyama, T., and Nishiyama M.
- Journal Title
  
  FEBS Journal
  
  Volume: 288 Issue: 6 Pages: 1975-1988
- DOI
  10.1111/febs.15527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria2020
- Author(s)
  Kei Sakaki, Keita Ohishi, Tetsu Shimizu, Ikki Kobayashi, Naoki Mori, Kenichi Matsuda, Takeo Tomita, Hidenori Watanabe, Kan Tanaka, Tomohisa Kuzuyama and Makoto Nishiyama
- Journal Title
  
  Nature Chem. Biol.
  
  Volume: 16 Issue: 4 Pages: 415-422
- DOI
  10.1038/s41589-019-0461-9
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04720, KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-18H02124
[Journal Article] Biochemical characterization of archaeal homocitrate synthase from Sulfolobus acidocaldarius2019
- Author(s)
  Suzuki, T., Akiyama, N., Ayako, Y., Tomita, T., Lassak, K., Haurat, M. F., Okada, T., Takahashi, K., Albers, S.-V., Kuzuyama, T., and Nishiyama, M.
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 1 Pages: 126-134
- DOI
  10.1002/1873-3468.13550
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-17J40083
[Journal Article] An ornithine ω-aminotransferase required for growth in the absence of exogenous proline in the archaeon Thermococcus kodakarensis2018
- Author(s)
  Zheng Ren-Chao、Hachisuka Shin-ichi、Tomita Hiroya、Imanaka Tadayuki、Zheng Yu-Guo、Nishiyama Makoto、Atomi Haruyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 10 Pages: 3625-3636
- DOI
  10.1074/jbc.ra117.001222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria2018
- Author(s)
  Matsuda Kenichi、Tomita Takeo、Shin-ya Kazuo、Wakimoto Toshiyuki、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Issue: 29 Pages: 9083-9086
- DOI
  10.1021/jacs.8b05354
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06448, KAKENHI-PLANNED-16H06453, KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-18H02581, KAKENHI-PROJECT-17F17114
[Journal Article] Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW2017
- Author(s)
  S. Fujita, F. Hasebe, S.-H. Cho, T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 491 Issue: 2 Pages: 409-415
- DOI
  10.1016/j.bbrc.2017.07.088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-17J40083
[Journal Article] Genome mining of amino group carrier protein-mediated machinery: discovery and biosynthetic characterization of a natural product with unique hydrazone unit2017
- Author(s)
  K. Matsuda, F. Hasebe, Y. Shiwa, Y. Kanesaki, T. Tomita, H. Yoshikawa, K. Shin-ya, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 12 Issue: 1 Pages: 124-131
- DOI
  10.1021/acschembio.6b00818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] Nobel stand-alone RAM-domain mediated catalytic control of anthranilate phosphoribosyltransferase in tryptophan biosynthesis in Thermus thermophilus2017
- Author(s)
  T. Kubota, H. Matsushita, T. Tomita, S. Kosono, M. Yoshida, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  Extremophiles
  
  Volume: 1 Issue: 1 Pages: 73-83
- DOI
  10.1042/bcj20160699
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07382, KAKENHI-PROJECT-17H06168
[Journal Article] Characterization of two β-decarboxylating dehydrogenases from Sulfolobus acidocaldarius2016
- Author(s)
  Takahashi Kento、Nakanishi Fumika、Tomita Takeo、Akiyama Nagisa、Lassak Kerstin、Albers Sonja-Verena、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Extremophiles
  
  Volume: 20 Issue: 6 Pages: 843-853
- DOI
  10.1007/s00792-016-0872-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Crystal structure of the LysY・LysW complex from Thermus thermophilus2016
- Author(s)
  Tetsu Shimizu, Takeo Tomita, Tomohisa Kuzuyama, and Makoto Nishiyama
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 19 Pages: 9948-9959
- DOI
  10.1074/jbc.m115.707034
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Amino group carrier protein-mediated secondary metabolite biosynthesis in Streptomyces.2016
- Author(s)
  Hasebe, F., Matsuda, K., Shiraishi, T., Futamura, Y., Nakano, T., Tomita, T., Ishigami, K., Taka, H., Mineki, R., Fujimura, T., Osada, H., Kuzuyama, T., Nishiyama, M.
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 12 Issue: 11 Pages: 967-972
- DOI
  10.1038/nchembio.2181
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14714, KAKENHI-PROJECT-16K01834, KAKENHI-PROJECT-24228001
[Journal Article] Lysine Biosynthesis ofThermococcus kodakarensiswith the Capacity to Function as an Ornithine Biosynthetic System2016
- Author(s)
  Yoshida Ayako、Tomita Takeo、Atomi Haruyuki、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 41 Pages: 21630-21643
- DOI
  10.1074/jbc.m116.743021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Determinants of dual substrate specificity revealed by the crystal structure of homoisocitrate dehydrogenase from Thermus thermophilus in complex with homoisocitrate・Mg2+・NADH2016
- Author(s)
  Takahashi Kento、Tomita Takeo、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 478 Issue: 4 Pages: 1688-1693
- DOI
  10.1016/j.bbrc.2016.09.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ•LysW complex from Thermus thermophilus2015
- Author(s)
  Ayako Yoshida, Takeo Tomita, Tsutomu Fujimura, Chiharu Nishiyama, Tomohisa Kuzuyama, and Makoto Nishiyama
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 290 Issue: 1 Pages: 435-447
- DOI
  10.1074/jbc.m114.595983
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24228001, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26870113
[Journal Article] Genome-wide comprehensive analysis of transcriptional regulation by ArgR in Thermus thermophilus2014
- Author(s)
  Naoki Iwanaga, Kaori Ide, Takeshi Nagashima, Takeo Tomita, Yoshihiro Agari, Akeo Shinkai, Seiki Kuramitsu, Mariko Okada-Hatakeyema, Tomohisa Kuzuyama, and Makoto Nishiyama
- Journal Title
  
  Extremophiles
  
  Volume: 18 Issue: 6 Pages: 995-1008
- DOI
  10.1007/s00792-014-0669-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Two ATP-binding cassette transporters involved in (S)-2-aminoethyl-cysteine uptake in Thermus thermophilus2013
- Author(s)
  Y. Kanemaru, F. Hasebe, T. Tomita, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 195 Issue: 17 Pages: 3845-3853
- DOI
  10.1128/jb.00202-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] ロイシンによるグルタミン酸脱水素酵素の活性調節機構2012
- Author(s)
  富田武郎、西山真
- Journal Title
  
  化学
  
  Volume: 67巻
- Data Source
  KAKENHI-PROJECT-22780084
[Journal Article] Structural basis for leucine-induced allosteric activation of glutamate dehydrogenase2011
- Author(s)
  T. Tomita, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 37406-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780084
[Journal Article] Structural basis for leucine-induced allosteric activation of glutamate de hydrogenase2011
- Author(s)
  Tomita, T., Kuzuyama, T., Nishiyama, M.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 37406-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780084
[Journal Article] Structural basis for leucine-induced allosteric activation of glutamate dehydrogenase2011
- Author(s)
  T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 37841-37848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Hetero-oligomeric glutamate dehydrogenase from Thermus thermophilus2010
- Author(s)
  T. Tomita, T. Miyazaki. J. Miyazaki, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Microbiology
  
  Volume: 156 Pages: 3801-3813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Enhancement of latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution2010
- Author(s)
  Y. Suzuki, K. Asada, J. Miyazaki, T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Biochem J
  
  Volume: 431 Pages: 401-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus2010
- Author(s)
  T. Okada, T. Tomita, A. P. Wulandari, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 4195-4205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Hetero-oligomeric glutamate dehydrogenase from Thermus thermophilus2010
- Author(s)
  T. Tomita, T. Miyazaki, J. Miyazaki, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  Microbiology
  
  Volume: 156 Pages: 3801-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780084
[Journal Article] Mechanism of concerted inhibition ofα_2β_2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum2010
- Author(s)
  A. Yoshida, T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 27477-27486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Mechanism for multiple-substrates recognition of α-aminoadipate aminotransferase from Thermus thermophilus2009
- Author(s)
  Tomita, T., et al.
- Journal Title
  
  Proteins-Structure Function and Bioinformatics 75
  
  Pages: 348-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates inα-aminoadipate aminotransferase from Thermus thermophilus2009
- Author(s)
  T. Ouchi, T. Tomita, T. Miyagawa, Kuzuyama, and M. Nishiyama
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 388 Pages: 2127-2127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus2009
- Author(s)
  A. Horie, T. Tomita, A. Saiki, H. Kono, H. Taka, R. Mineki, T. Fujimura, C. Nishiyama, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Nat Chem Biol
  
  Volume: 5 Pages: 673-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Mechanism for multiple-substrates recognition ofα-aminoadipate aminotransferase from Thermus thermophilus2009
- Author(s)
  T. Tomita, T. Miyagawa, T. Miyazaki, S. Fushinobu, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Proteins
  
  Volume: 75 Pages: 348-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase from Thermus thermophilus2009
- Author(s)
  A. Yoshida, T. Tomita, H. Kono, S. Fushinobu, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  FEBS J
  
  Volume: 276 Pages: 3124-3136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Crystal structure of regulatory subunit of aspartate kinase from Thermus thermophilus2009
- Author(s)
  A. Yoshida, T. Tomita, H, Kono, S. Fushinobu, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  FEBS Journal 276
  
  Pages: 3124-3136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780054
[Journal Article] Structural insight into concerted inhibition of α_2β _2-type aspartate kinase from Corynebacterium glutamicum2007
- Author(s)
  A. Yoshida, T. Tomita, T. Kurihara, S. Fushinobu, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  J. Mol. Biol 368
  
  Pages: 521-536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780054
[Journal Article] Purification, crystallization, and preliminary X-ray analysis of the regulatory subunit of aspartate kinase from Thermus thermophilus2007
- Author(s)
  A. Yoshida, T. Tomita, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  Acta Crystallogr F. 63
  
  Pages: 96-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780054
[Journal Article] Purification, crystallization and preliminary X-ray analysis of the regula tory subunit of aspartate kinase from Thermus ther2007
- Author(s)
  Yoshida, A., Tomita, T., Kuzuyama, T., and M. Nishiyama.
- Journal Title
  
  Acta Crystallography Section F. 63
  
  Pages: 96-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780054
[Journal Article] Structural Insight into concerted inhibition of alpha2beta2-type aspartate kinase from Corynebacterium glutamicum2007
- Author(s)
  Yoshida, A., Tomita, T., Kurihara, T., Fushinobu, S., Kuzuyama, T., and M. Nishiyama.
- Journal Title
  
  Journal of Molecular Biology 368
  
  Pages: 521-536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] 高度好熱菌Thermus thermophilus由来アデニンホスホリボシルトランスフェラーゼとそのホモログの結晶構造解析による触媒機構と機能分化様式の解析2022
- Author(s)
  富田　武郎,　西山　真
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-21K05358
[Presentation] 高度好熱菌Thermus thermophilus由来アデニンホスホリボシルトランスフェラーゼとそのホモログの結晶構造解析による触媒機構と機能分化様式の解明2022
- Author(s)
  富田武郎、西山真
- Organizer
  日本農芸化学会　2022年度大会
- Data Source
  KAKENHI-PROJECT-21K05358
[Presentation] 放線菌由来1-azabicyclo[3.1.0]hexane環含有化合物におけるアジリジン環合成機構の解明2022
- Author(s)
  黒澤菫、長谷部文人、岡村仁則、吉田彩子、富田武郎、滝川浩郷、古園さおり、西山真
- Organizer
  2022年度日本農芸化学会　京都大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 高度好熱菌Thermus thermophilusのグルタミン酸脱水素酵素における酵素ホモログとの相互作用を介したアロステリック調節機構2021
- Author(s)
  富田武郎
- Organizer
  極限環境生物学会2021年度 (第22回) 年会
- Data Source
  KAKENHI-PROJECT-21K05358
[Presentation] Studies on the biosynthetic machinery in secondary metabolism of Streptomyces to form 1-azabicyclo[3.1.0]hexane ring via aziridine ring2021
- Author(s)
  Sumire KUROSAWA, Kenichi MATSUDA, Fumihito HASEBE, Takeo TOMITA, Tomohisa KUZUYAMA, Saori KOSONO, Makoto NISHIYAMA
- Organizer
  日本農芸化学会　2021年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Serratia sp. ATCC 39006におけるアミノ基キャリアタンパク質を介した生合成についての研究2020
- Author(s)
  平島佑樹、曽根祐輔、菊池恒志郎、富田武郎、葛山智久、古園さおり、西山真
- Organizer
  日本農芸化学会　2020年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 放線菌の生産するアザビシクロ環含有化合物vazabitide A生合成におけるアジリジン環合成経路に関する研究2020
- Author(s)
  黒澤菫、松田研一、長谷部文人、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会　2020年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Maleimycin Biosynthesis is mediated by Type II Amino-group Carrier Protein in Streptomyces sp.2019
- Author(s)
  Muhammad Prima Putra, Kenichi Matsuda, Takeo Tomita, Kazuo Shin-ya, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldarius由来のホモクエン酸合成酵素の構造・機能解析2019
- Author(s)
  鈴木智大、富田武郎、葛山智久、西山真
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] アザビシクロ環含有ジペプチドficellomycinの生合成機構に関する研究2019
- Author(s)
  黒澤菫、松田研一、長谷部文人、富田武郎、葛山智久、西山真
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] ficellomycin生合成におけるアザビシクロ環の修飾機構に関する研究2018
- Author(s)
  黒澤菫、松田研一、長谷部文人、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldariusのホモクエン酸合成酵素の構造・機能及びフィードバック阻害機構の解析2018
- Author(s)
  鈴木智大、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Studies on Secondary Metabolic Pathway Mediated by Type II Amino-group Carrier Protein in Streptomyces sp.2018
- Author(s)
  M. Prima PUTRA , K. Matsuda, T. Tomita, K. Shin-ya, T. Kuzuyama, M. Nishiyama
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Regulatory mechanism of glutamate dehydrogenase from Thermus thermophilus2017
- Author(s)
  Takeo Tomita
- Organizer
  Italy-Japan Joint Symposium New Trends in Enzyme and Micribial Science in the Translational Biologyl Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07382
[Presentation] Discovery and biosynthetic characterization of a natural product biosynthesized via AmCP-mediated pathway2017
- Author(s)
  Kenichi Matsuda, Fumihito Hasebe, Yuh Shiwa, Yu Kanesaki, Takeo Tomita, Hirofumi Yoshikawa, Kazuo Shin-ya, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  Directing Biosynthesis V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] テルペン合成酵素の機能改変とグルタミン酸脱水素酵素の調節機構2017
- Author(s)
  富田　武郎
- Organizer
  第６回　日本生物工学会東日本支部コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-15K07382
[Presentation] Studies on secondary metabolic pathway mediated by type II amino-group carrier protein (AmCP)in Streptomyces sp.2017
- Author(s)
  M. Prima Putra,K. Naito, K. Matsuda, T. Tomita, K. Shin-ya, T. Kuzuyama, M. Nishiyama
- Organizer
  日本放線菌学会2017年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 好熱菌Thermus thermophilus由来のリジン生合成系酵素LysKとキャリアタンパク質LysWの相互作用機構に関する研究2017
- Author(s)
  藤田理美、長谷部文人、CHO Su-Hee、富田武郎、葛山智久、西山　真
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldariusにおけるアルギニン生合成酵素遺伝子の転写調節機構に関する研究2017
- Author(s)
  中西史佳、富田武郎、葛山智久、西山　真
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Streptomyces sp. SpE090715-01 produces a maleimycin-like compound using amino-group carrier protein (AmCP)2017
- Author(s)
  Muhammad Prima PUTRA, Naito KAZUHIRO, Matsuda KENICHI, Tomita TAKEO, Shin-ya KAZUO, Kuzuyama TOMOHISA, Nishiyama MAKOTO
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基結合型キャリアタンパク質を介したリジン生合成メタボロンの解析2016
- Author(s)
  清水　哲、富田武郎、葛山智久、西山　真
- Organizer
  生命システム原材料の起源と進化研究会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基キャリアタンパク質を介したリジン生合成酵素LysYの基質認識機構の構造基盤2016
- Author(s)
  清水哲、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ酸キャリアタンパク質(AmCP)を介して生合成されるアミノ酸DADH修飾酵素の同定2016
- Author(s)
  長谷部文人、松田研一、白石太郎、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基キャリアタンパク質を指標とした新規天然化合物の探索及びその生合成に関する研究2016
- Author(s)
  松田研一、長谷部文人、富田武郎、志波優、兼崎友、吉川博2、新家一男、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] II型アミノ基キャリアタンパク質を介した二次代謝産物の生合成に関する研究2016
- Author(s)
  内藤一洋、松田研一、長谷部文人、富田武郎、手塚武揚、大西康2、志波優、吉川博文、新家一男、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Thermus thermophilus由来アデニンホスホリボシルトランスフェラーゼホモログの構造・機能解析2016
- Author(s)
  富田武郎、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07382
[Presentation] Thermus thermophilus における Stand-alone RAM ドメインタンパク質を介した新規トリプトファン生合成調節と生理的意義の解明2016
- Author(s)
  久保田哲央、松下創、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07382
[Presentation] アミノ酸代謝に関わる酵素に関する構造生物学的研究2016
- Author(s)
  富田武郎
- Organizer
  日本農芸化学会第一回関東支部例会
- Place of Presentation
  東京農業大学世田谷キャンパス（東京都世田谷区）
- Data Source
  KAKENHI-PROJECT-15K07382
[Presentation] First reaction intermediate complex of glutamate dehydrogenase from Corynebacterium glutamicum2013
- Author(s)
  Takeo Tomita, Makoto Nishiyama
- Organizer
  International conference on structural genomics 2013
- Place of Presentation
  京王プラザホテル（札幌）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Biosynthetic machinery of secondary metabolites using amino acid carrier protein in Streptomyces2013
- Author(s)
  Fumihito Hasebe, Takeo Tomita, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  17th German-Japanese Workshop on Enzyme Technology
- Place of Presentation
  Technical University of Hamburg-Harburg
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] N-protecting protein LysW functions as a carrier protein in lysine biosynthesis on Thermus thremophilus2013
- Author(s)
  Ayako Yoshida, Takeo Tomita, Saori Kosono, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  17th German-Japanese Workshop on Enzyme Technology
- Place of Presentation
  Technical University of Hamburg-Harburg
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 高度好熱菌Thermus thermophilus におけるアミノ酸シグナル応答機構の解析2013
- Author(s)
  久保田哲央、松下創、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会関東支部2013 年度支部大会
- Place of Presentation
  慶應義塾大学日吉キャンパス・藤原洋記念ホール(横浜）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Corynebacterium glutamicum由来グルタミン酸脱水素酵素の結晶構造解析2013
- Author(s)
  富田武郎、インルル、葛山智久、西山真
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] LysRファミリー転写制御因子TTC1871の機能解析2013
- Author(s)
  松下創、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Mechanism for hyper-sensitivity to lysine analogue of Thermus thermophilus HB272013
- Author(s)
  Yuko Kanameru, Fumihito Hasebe, Takeo Tomita, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  The 3rd Annual Meeting for Whole-Organizm Science society
- Place of Presentation
  大阪大学豊中キャンパスシグマホール（大阪）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] The first reaction intermediate complex of glutamate dehydrogenase from corynebacterium glutamicum2013
- Author(s)
  Takeo Tomita
- Organizer
  Enzyme Engineering XXII
- Place of Presentation
  富山国際会議場（富山）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Substrate recognition mechanism of a homolog of homoisocitratedehydrogenase from Thermococcus kodakarensis, TK02802012
- Author(s)
  ○Takeo Tomita, Yin Lu Lu, Kento Takahashi, Haruyuki Atomi, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  第2回モデル生物丸ごと一匹学会
- Place of Presentation
  理化学研究所播磨研究所（播磨）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Substrate recognition mechanism of a homolog of homoisocitrate dehydrogenase from Thermococcus kodakarensis, TK02802012
- Author(s)
  Takeo Tomita
- Organizer
  The 2nd Annual Meeting for Whole-Organism Science Society
- Place of Presentation
  SPring-8（兵庫県）
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Functional analysis of TTC1871 LysR-type transcriptional regulator2012
- Author(s)
  Matsushita Hajime, Takeo Tomita, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  第2回モデル生物丸ごと一匹学会
- Place of Presentation
  理化学研究所播磨研究所（播磨）
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] ロイシンによるグルタミン酸脱水素酵素のアロステリック調節機構の解析2012
- Author(s)
  富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(京都)
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] 高度好熱菌Thermus thermophilus由来グルタミン酸脱水素酵素のロイシンによるアロステリック調節機構の構造基盤2012
- Author(s)
  富田武郎、葛山智久、西山真
- Organizer
  2011年度日本農芸化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] Mechanism for allosteric regulation of glutamate dehydrogense from Thermus thermophilus2012
- Author(s)
  富田武郎、西山真
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] グルタミン酸脱水素酵素の新規活性調節機構の発見2011
- Author(s)
  西山真、富田武郎
- Organizer
  2010年度日本農芸化学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] 高度好熱菌Thermus thermophilus由来グルタミン酸脱水素酵素のロイシンによるアロステリック調節の構造基盤2011
- Author(s)
  富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2011年度大会(京都)
- Place of Presentation
  京都
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] 高度好熱菌Thermus thermophilusのグルタミン酸脱水素酵素(GDH)の活性調節サブユニットGdhAの結晶構造解析2011
- Author(s)
  富田武郎、葛山智久、西山真
- Organizer
  2010年度日本農芸化学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] Leucine-mediated signal transduction in Thermus thermophilus2011
- Author(s)
  松下創、富田武郎、葛山智久、西山真
- Organizer
  第1回モデル生物丸ごと一匹学会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] Mechanism of leucine-induced allosteric activation of glutamate dehydro genase2011
- Author(s)
  富田武郎、西山真
- Organizer
  第1回モデル生物丸ごと一匹学会
- Place of Presentation
  理化学研究所播磨研究所(兵庫)
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] Mechanism of leucine-induced allosteric activation of glutamate dehydrogenase2011
- Author(s)
  富田武郎、西山真
- Organizer
  第1回モデル生物丸ごと一匹学会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] Mechanism for Allosteric Regulation of Glutamate Dehydrogenase from Thermus thermophilius2010
- Author(s)
  富田武郎、葛山智久、西山真
- Organizer
  アメリカ結晶学会2010 Annual meeting
- Place of Presentation
  シカゴ USA
- Year and Date
  2010-07-25
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] グルタミン酸脱水素酵素の新規活性調節機構の発見2010
- Author(s)
  西山真、富田武郎
- Organizer
  日本農芸化学会2010年度大会シンポジウム
- Place of Presentation
  駒場、東京
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Regulatory mechanism of glutamate dehydrogenase from Thermus thermophilus2010
- Author(s)
  富田武郎、西山真
- Organizer
  2010 Annual meeting of American Crystallographic Association
- Place of Presentation
  (ACA)(シカゴ)
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] Mulecular mechanism for allosteric regulation of glutamatedehydrogenase from Thermus thermophilus2010
- Author(s)
  富田武郎、西山真
- Organizer
  高度好熱菌丸ごと一匹プロジェクト第9回連携研究会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] 高度好熱菌Thermus thermophilusのグルタミン酸脱水素酵素(GDH)の活性調節サブユニットGdhAの結晶構造解析2010
- Author(s)
  富田武郎, ら
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京大学
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] グルタミン酸脱水素酵素の新規活性調節機構の発見2010
- Author(s)
  西山真、富田武郎
- Organizer
  日本農芸化学会2010年度大会シンポジウム「酵素・タンパク質のユニークな活性調節機構および機能発現の新展開」
- Place of Presentation
  東京大学
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Thermus thermophilus由来グルタミン酸脱水素酵素における活性調節の分子機構の解析2010
- Author(s)
  富田武郎、西山真
- Organizer
  高度好熱菌丸ごと一匹プロジェクト第9回連携研究会
- Place of Presentation
  播磨(Spring-8)
- Year and Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-22780084
[Presentation] Corynebacterium glutamcum加由来のアスパラギン酸キナーゼの活性制御機構の解析2009
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山
- Organizer
  2009年度日本農芸化学会大会
- Place of Presentation
  福岡
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] 高度好熱菌Thermus thermophilus由来グルタミン酸脱水素酵素における活性調節の分子機構の解析2009
- Author(s)
  富田武郎, ら
- Organizer
  理研シンポジウム(高度好熱菌丸ごと-匹プロジェクト第8回連携研究会)
- Place of Presentation
  理研播磨研
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Corynebacterium glutamicum 由来のアスパラギン酸キナーゼ(の活性制御機構の解析2009
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山真
- Organizer
  2009年度日本農芸化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] Corynebacterium glutamicum 由来アスパラギン酸キナーゼ(AK)の活性制御機構の解析2008
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山真
- Organizer
  2008年度日本農芸化学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] Corynebacterium glutamicum 由来のアスパラギン酸キナーゼ(AK)の活性調節機構の解析2008
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山真
- Organizer
  第8回蛋白質科学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] Corynebacterium glutamicum由来のアスパラギン酸キナーゼ(AK)の活性制御機構の解2008
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山
- Organizer
  第8回日本蛋白質科学会年会
- Place of Presentation
  東京
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] Thermus thermophilus由来アスパラギン酸キナーゼ活性制御サブユニットの結晶構造解析2007
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山真
- Organizer
  理研セミナー「高度好熱菌丸ごと一匹プロジェクト第6回連携研究会」
- Place of Presentation
  相生(兵庫)
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] Corynebacterium glutamicum由来アスパラギン酸キナーゼ(AK)の活性制御機構の解析2007
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山真
- Organizer
  2008年度日本農芸化学会大会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-27
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] Thermus thermophilus 由来アスパラギン酸キナーゼ活性制御サブユニットの結晶構造解析2007
- Author(s)
  吉田彩子、富田武郎、葛山智久、西山真
- Organizer
  理研セミナー「高度好熱菌丸ごと一匹プロジェクト第6回連携研究会」
- Data Source
  KAKENHI-PROJECT-19780054
[Presentation] アミノ基結合型キャリアタンパク質を指標とした新規天然化合物の探索
- Author(s)
  松田研一、長谷部文人、富田武郎、志波優、吉川博文、新家一男、葛山智久、西山真
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田校舎
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Function and regulation of enzymes involved in amino acid biosynthesis of Sulfolobus acidocaldarius
- Author(s)
  Takeo Tomita, Kento Takahashi, Nagisa Akiyama, and Makoto Nishiyama
- Organizer
  第4回モデル生物丸ごと一匹学会
- Place of Presentation
  大阪
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Secondary metabolites biosynthesized using AmCP, a novel amino acid carrier protein, in Actinomycetes
- Author(s)
  Kenichi Matsuda, Fumihito Hasebe, Takeo Tomita, Yu Shiwa, Hirofumi Yoshikawa, Kazuo Shin-ya, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  Japan-Italy Symposium
- Place of Presentation
  Nara
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 古細菌Sulfolobus acidocaldariusのアミノ酸生合成経路を構成する酵素の機能・構造解析
- Author(s)
  富田武郎、高橋賢人、秋山　渚、西山　真
- Organizer
  第15回極限環境生物学会
- Place of Presentation
  沖縄
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Characterization of an ancestral-type β-decarboxylating dehydrogenase from Thermococcus kodakarensis
- Author(s)
  Tetsu Shimizu, Lulu Yin, Kento Takahashi, Takeo Tomita, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  第4回モデル生物丸ごと一匹学会
- Place of Presentation
  大阪
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 原始型β脱炭酸脱水素酵素の機能と構造基盤
- Author(s)
  清水　哲、伊　録録、高橋賢人、富田武郎、葛山智久、西山　真
- Organizer
  第5回醗酵学フォーラム
- Place of Presentation
  湯河原
- Year and Date
  2014-11-23 – 2014-11-24
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 高度好熱菌Thermus thermophilus におけるアミノ酸シグナル伝達機構の解析
- Author(s)
  Tetsuo Kubota, Hajime Matsushita, Takeo Tomita, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  第４回モデル生物丸ごと一匹学会
- Place of Presentation
  大阪大学豊中キャンパス
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Thermus thermophilus 由来アデニンホスホリボシルトランスフェラーゼホモログの構造・機能解析
- Author(s)
  富田武郎，西山　真
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-26 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldariusにおけるアミノ酸生合成経路の調節機構の解析
- Author(s)
  秋山渚、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田校舎
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 高度好熱菌 Thermus thermophilus におけるアミノ酸シグナル応答機構の解析
- Author(s)
  久保田哲央，松下　創，富田武郎，葛山智久，西山　真
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-26 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Crystal structure and insight into extremely high glutamate production acivity of glutamate dehydrogenase from Corynebacterium glutamicum
- Author(s)
  Takeo Tomita, Shugo Nakamura , and Makoto Nishiyama
- Organizer
  Active enzyme molecule 2014
- Place of Presentation
  富山国際会議場
- Year and Date
  2014-12-17 – 2014-12-19
- Data Source
  KAKENHI-PROJECT-24580137
[Presentation] Thermococcus kodakarensis由来の祖先型β-脱炭酸脱水素酵素の機能と構造基盤の解析
- Author(s)
  清水　哲、伊　録録、高橋賢人、富田武郎、葛山智久、西山　真
- Organizer
  第15回極限環境生物学会
- Place of Presentation
  沖縄
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Screening of secondary metabolites biosynthesized with novel amino acid carrier protein system
- Author(s)
  Kenichi Matsuda, Fumihito Hasebe, Takeo Tomita, Yu Shiwa, Hirofumi Yoshikawa, Kazuo Shin-ya, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  2014 ASBMB Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ酸キャリアタンパク質を介して生合成される新規アミノ酸とその代謝産物の同定
- Author(s)
  長谷部文人、富田武郎、高ひかり、藤村努、西山千春、葛山智久、西山真
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田校舎
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基結合型キャリアタンパク質を指標とした新規天然化合物の探索
- Author(s)
  松田研一、長谷部文人、富田武郎、志波　優、吉川博文、新家一男、葛山智久、西山真
- Organizer
  第49回天然物化学談話会
- Place of Presentation
  倉敷
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ酸キャリアタンパク質を介して生合成される新規アミノ酸とその代謝産物の同定
- Author(s)
  長谷部文人、富田武郎、高ひかり、藤村　務、西山千春、葛山智久、西山　真
- Organizer
  第49回天然物化学談話会
- Place of Presentation
  倉敷
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Structure and function of an ancestral-type β-decarboxylating dehydrogenase from Thermococcus kodakarensis
- Author(s)
  Tetsu Shimizu, Lulu Yin, Kento Takahashi, Takeo Tomita, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  Active Enzyme Molecule 2014
- Place of Presentation
  Toyama
- Year and Date
  2014-12-17 – 2014-12-19
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] The first reaction intermediate complex of glutamate dehydrogenase
- Author(s)
  Takeo Tomita, Makoto Nishiyama
- Organizer
  ASBMB annual meeting
- Place of Presentation
  San diego Convention Center
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-24580137

1. NISHIYAMA Makoto (00208240)

# of Collaborated Projects: 5 results

# of Collaborated Products: 58 results
2. WAKIMOTO Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 田中寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 中野雄司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOMITA Takeo 富田 武郎

Research Projects

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Exploration and biochemical characterization of novel regulatory mechanisms of bacterial glutamate dehydrogenasesPrincipal Investigator

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Studies on mechanisms of biosynthesis of biomolecules via amino-group carrier protein and expansion of structural diversity of secondary metabolites

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Elucidation of structures and functions of metabolic enzymes of lysine and related compounds and their molecular evolution

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Molecular mechanism of amino acid signal transduction system in thermophilic bacteriumPrincipal Investigator

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Elucidation of mechanisms of biomaterial conversion mediated by amino group-modifying carrier protein and application

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リジン生合成および関連一次代謝系酵素群の機能および分子進化の解析

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Functional analysis and molecular basis of leucine as a biological regulatorPrincipal Investigator

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Mechanism of leucine signaling of Thermus thermophilusPrincipal Investigator

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Structural biology for elucidation of lysine biosynthesis and its regulatory mechanisms

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Analysis of regulatory mechanism of aspartate kinasePrincipal Investigator

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[Book] 化学2012

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[Journal Article] Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius2021

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[Journal Article] A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria2020

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[Journal Article] Biochemical characterization of archaeal homocitrate synthase from Sulfolobus acidocaldarius2019

TOMITA Takeo 富田武郎