Tsuge Masataka 柘植雅貴

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TSUGE MASATAKA 柘植雅貴

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Researcher Number	50448263
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(医), 教授
Affiliation (based on the past Project Information) *help	2024: 広島大学, 医系科学研究科(医), 教授 2022 – 2023: 広島大学, 医系科学研究科(医), 准教授 2021: 広島大学, 自然科学研究支援開発センター, 講師 2015 – 2020: 広島大学, 自然科学研究支援開発センター, 助教 2017: 広島大学, 学内共同利用施設等, 助教 2012 – 2013: 広島大学, 自然科学研究支援開発センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Infectious disease medicine
Keywords	Principal Investigator ヒト肝細胞キメラマウス / B型肝炎ウイルス / B型肝炎 / 遺伝子発現解析 / インターフェロン / 抗ウイルス効果 / キメラマウス / 発癌シグナル / 免疫応答 / TRAIL-R3 … More / 次世代シークエンス解析 / 免疫寛容 / cccDNA / ヒト肝細胞 / ウイルス動態 / 治療抵抗性 / 遺伝子発現 / 核酸アナログ / 治療 Less

Analysis of hepatocarcinogenesis in hepatocytes with hepatitis B virus infectionPrincipal Investigator
- Principal Investigator
  
  柘植雅貴
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hiroshima University
Analysis of immune response mechanisms of CTL and NK cells in HBV infection HBV infectionPrincipal Investigator
- Principal Investigator
  
  Tsuge Masataka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hiroshima University
Association analysis between the suppression of interferon responsiveness by HBV infection and changes of gene expression in human hepatocytesPrincipal Investigator
- Principal Investigator
  
  Tsuge Masataka
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University
Analyses of antiviral mechanisms by interferon treatment on hepatitis B virus replicationPrincipal Investigator
- Principal Investigator
  
  TSUGE MASATAKA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hiroshima University
Analysis of mechanisms for suppressing interferon responsiveness by chronic hepatitis B virus infectionPrincipal Investigator
- Principal Investigator
  
  TSUGE MASATAKA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University
Basic research for clarifing the phathologic characteristics with HBV genotype A infectionPrincipal Investigator
- Principal Investigator
  
  TSUGE MASATAKA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Hiroshima University

[Book] 専門医のための消化器病学第3版2021
- Author(s)
  柘植雅貴、茶山一彰
- Total Pages
  736
- Publisher
  医学書院
- ISBN
  9784260045797
- Data Source
  KAKENHI-PROJECT-21K08006
[Book] 「HBV の感染実験系」Hepatology Practice 第1巻 B型肝炎の診療を極める2013
- Author(s)
  柘植雅貴, 茶山一彰
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24791023
[Book] 「B型肝炎, D型肝炎」カラー版消化器病学2013
- Author(s)
  柘植雅貴, 茶山一彰
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-24791023
[Book] Hepatology Practice 第1巻　B型肝炎の診療を極める2013
- Author(s)
  柘植雅貴、茶山一彰
- Total Pages
  205
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24791023
[Book] カラー版　消化器病学2013
- Author(s)
  柘植雅貴、茶山一彰
- Total Pages
  1541
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-24791023
[Journal Article] Acute liver injury in a non-alcoholic fatty liver disease patient with chloroform exposure: a case report2023
- Author(s)
  Suehiro Yosuke、Uchida Takuro、Tsuge Masataka、Murakami Eisuke、Miki Daiki、Kawaoka Tomokazu、Imamura Michio、Aikata Hiroshi、Arihiro Koji、Oka Shiro
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 16 Pages: 250-253
- DOI
  10.1007/s12328-023-01760-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics2023
- Author(s)
  Hailegiorgis Atesmachew、Ishida Yuji、Collier Nicholson、Imamura Michio、Shi Zhenzhen、Reinharz Vladimir、Tsuge Masataka、Barash Danny、Hiraga Nobuhiko、Yokomichi Hiroshi、Tateno Chise、Ozik Jonathan、Uprichard Susan L.、Chayama Kazuaki、Dahari Harel
- Journal Title
  
  PLOS Computational Biology
  
  Volume: 19 Issue: 8 Pages: 1011309-1011309
- DOI
  10.1371/journal.pcbi.1011309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Factors for the recurrence of hepatocellular carcinoma after hepatic resection2023
- Author(s)
  Tsuge Masataka、Kawaoka Tomokazu、Oka Shiro
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 58 Issue: 3 Pages: 292-293
- DOI
  10.1007/s00535-023-01962-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Correlation between serum pro‐inflammatory cytokine levels and the prognosis of the patients with acute liver failure2023
- Author(s)
  Murakami S, Uchida T, Imamura M, Suehiro Y, Namba M, Fujii Y, Uchikawa S, Teraoka Y, Fujino H, Ono A, Nakahara T, Murakami E, Okamoto W, Yamauchi M, Kawaoka T, Miki D, Hayes CN, Tsuge M, Ohira M, Ohdan H, Oka S.
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 38 Issue: 9 Pages: 1637-1646
- DOI
  10.1111/jgh.16300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Hepatitis B Virus (HBV) Upregulates TRAIL-R3 Expression in Hepatocytes Resulting in Escape From Both Cell Apoptosis and Suppression of HBV Replication by TRAIL2022
- Author(s)
  Suehiro Yosuke、Tsuge Masataka、Kurihara Mio、Uchida Takuro、Fujino Hatsue、Ono Atsushi、Yamauchi Masami、Naswa Makokha Grace、Nakahara Takashi、Murakami Eisuke、Abe-Chayama Hiromi、Kawaoka Tomokazu、Miki Daiki、Imamura Michio、Aikata Hiroshi、Nelson Hayes C、Fujita Takashi、Chayama Kazuaki
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 227 Issue: 5 Pages: 686-695
- DOI
  10.1093/infdis/jiac044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Intranasal therapeutic vaccine containing HBsAg and HBcAg for patients with chronic hepatitis B; 18?months follow‐up results of phase IIa clinical study2022
- Author(s)
  Yoshida Osamu、Akbar Sheikh Mohammad Fazle、Imai Yusuke、Sanada Takahiro、Tsukiyama‐Kohara Kyoko、Miyazaki Takashi、Kamishita Taizou、Miyake Teruki、Tokumoto Yoshio、Hikita Hayato、Tsuge Masataka、Shimizu Masahito、Al Mahtab Mamun、Aguilar Julio Cesar、Guillen Gerardo、Kohara Michinori、Hiasa Yoichi
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 3 Pages: 196-207
- DOI
  10.1111/hepr.13851
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07983, KAKENHI-PROJECT-21K08006, KAKENHI-PROJECT-22K07096, KAKENHI-PROJECT-19K16680
[Journal Article] Construction of an anti-hepatitis B virus preS1 antibody and usefulness of preS1 measurement for chronic hepatitis B patients2022
- Author(s)
  Hatooka Haruna、Shimomura Yumi、Imamura Michio、Teraoka Yuji、Morio Kei、Fujino Hatsue、Ono Atsushi、Nakahara Takashi、Murakami Eisuke、Yamauchi Masami、Kawaoka Tomokazu、Makokha Grace Naswa、Miki Daiki、Tsuge Masataka、Hiramatsu Akira、Abe-Chayama Hiromi、Hayes C. Nelson、Aikata Hiroshi、Tanaka Shinji、Chayama Kazuaki
- Journal Title
  
  Journal of Infection
  
  Volume: 84 Issue: 3 Pages: 391-399
- DOI
  10.1016/j.jinf.2021.12.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Serum miR-192-5p levels predict the efficacy of pegylated interferon therapy for chronic hepatitis B2022
- Author(s)
  Nagura Yoshihito、Matsuura Kentaro、Iio Etsuko、Fujita Koji、Inoue Takako、Matsumoto Akihiro、Tanaka Eiji、Nishiguchi Shuhei、Kang Jong-Hon、Matsui Takeshi、Enomoto Masaru、Ikeda Hiroki、Watanabe Tsunamasa、Okuse Chiaki、Tsuge Masataka、Atsukawa Masanori、Tateyama Masakuni、Kataoka Hiromi、Tanaka Yasuhito
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 2 Pages: e0263844-e0263844
- DOI
  10.1371/journal.pone.0263844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-21K08006
[Journal Article] The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro2022
- Author(s)
  Gad Sameh A.、Sugiyama Masaya、Tsuge Masataka、Wakae Kosho、Fukano Kento、Oshima Mizuki、Sureau Camille、Watanabe Noriyuki、Kato Takanobu、Murayama Asako、Li Yingfang、Shoji Ikuo、Shimotohno Kunitada、Chayama Kazuaki、Muramatsu Masamichi、Wakita Takaji、Nozaki Tomoyoshi、Aly Hussein H.
- Journal Title
  
  PLOS Pathogens
  
  Volume: 18 Issue: 3 Pages: 1-26
- DOI
  10.1371/journal.ppat.1009983
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07586, KAKENHI-PROJECT-19K23855, KAKENHI-PROJECT-21K08006, KAKENHI-PROJECT-19H04354
[Journal Article] Increasing incidence of non-HBV- and non-HCV-related hepatocellular carcinoma: single-institution 20-year study.2021
- Author(s)
  Nagaoki Y, Hyogo H, Ando Y, Kosaka Y, Uchikawa S, Nishida Y, Teraoka Y, Morio K, Fujino H, Ono A, Nakahara T, Murakami E, Yamauchi M, Okamoto W, Kawaoka T, Tsuge M, Hiramatsu A, Miki D, Imamura M, Takahashi S, Chayama K, Aikata H.
- Journal Title
  
  BMC Gastroenterol.
  
  Volume: 21(1) Issue: 1 Pages: 306-306
- DOI
  10.1186/s12876-021-01884-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08288, KAKENHI-PROJECT-21K07896, KAKENHI-PROJECT-21K08006
[Journal Article] インターフェロンによるB型肝炎ウイルス増殖抑制メカニズムに関する検討2021
- Author(s)
  柘植　雅貴
- Journal Title
  
  Medical Science Digest
  
  Volume: 47 Pages: 43-46
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Serum PreS1 and HBsAg ratio reflects liver fibrosis and predicts the development of hepatocellular carcinoma in chronic hepatitis B patients2021
- Author(s)
  Nishida Y、Imamura M、Teraoka Y、Morio K、Fujino H、Ono A、Nakahara T、Murakami E、Yamauchi M、Kawaoka T、Miki D、Tsuge M、Hiramatsu A、Abe‐Chayama H、Hayes CN、Aikata H、Sasaki N、Sekiguchi T、Kinukawa H、Yoshimura T、Chayama K
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: 28 Issue: 9 Pages: 1304-1311
- DOI
  10.1111/jvh.13557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] MafF is an antiviral host factor that suppresses transcription from Hepatitis B Virus core promoter2021
- Author(s)
  Ibrahim Marwa K.、Abdelhafez Tawfeek H.、Takeuchi Junko S.、Wakae Kosho、Sugiyama Masaya、Tsuge Masataka、Ito Masahiko、Watashi Koichi、El Kassas Mohamed、Kato Takanobu、Murayama Asako、Suzuki Tetsuro、Chayama Kazuaki、Shimotohno Kunitada、Muramatsu Masamichi、Aly Hussein H.、Wakita Takaji
- Journal Title
  
  Journal of Virology
  
  Volume: 「－」 Issue: 15
- DOI
  10.1128/jvi.00767-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07586, KAKENHI-PROJECT-18F18098, KAKENHI-PROJECT-20J40110, KAKENHI-PROJECT-19K07583, KAKENHI-PROJECT-21K07051, KAKENHI-PROJECT-21K08006, KAKENHI-PROJECT-17K15708
[Journal Article] Are Humanized Mouse Models Useful for Basic Research of Hepatocarcinogenesis through Chronic Hepatitis B Virus Infection?2021
- Author(s)
  Tsuge Masataka
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 10 Pages: 1920-1920
- DOI
  10.3390/v13101920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Understanding Hepatitis B Virus Dynamics and the Antiviral Effect of Interferon Alpha Treatment in Humanized Chimeric Mice2021
- Author(s)
  Reinharz Vladimir、Ishida Yuji、Tsuge Masataka、Durso-Cain Karina、Chung Tje Lin、Tateno Chise、Perelson Alan S.、Uprichard Susan L.、Chayama Kazuaki、Dahari Harel
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 14
- DOI
  10.1128/jvi.00492-20
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] The association between hepatocarcinogenesis and intracellular alterations due to hepatitis B virus infection2021
- Author(s)
  Tsuge Masataka
- Journal Title
  
  Liver International
  
  Volume: 41 Issue: 12 Pages: 2836-2848
- DOI
  10.1111/liv.15065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08006
[Journal Article] Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B2020
- Author(s)
  Matsumoto A, Nishiguchi S, Enomoto H, Tanaka Y, Shinkai N, Okuse C, Kang JH, Matsui T, Miyase S, Yatsuhashi H, Nagaoka S, Kanda T, Enomoto M, Yamada R, Hiramatsu N, Saito S, Takaguchi K, Ito K, Masaki T, Morihara D, Tsuge M, Chayama K, Ikeda F, Kagawa T, Kondo Y, Murata K, Tanaka E.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 55(10) Issue: 10 Pages: 977-989
- DOI
  10.1007/s00535-020-01707-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08374, KAKENHI-PROJECT-19K08479, KAKENHI-PROJECT-18K07973
[Journal Article] Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection-Pilot study2020
- Author(s)
  Teraoka Yuji、Imamura Michio、Uchida Takuro、Ohya Kazuki、Morio Kei、Fujino Hatsue、Ono Atsushi、Nakahara Takashi、Murakami Eisuke、Yamauchi Masami、Kawaoka Tomokazu、Miki Daiki、Tsuge Masataka、Hiramatsu Akira、Abe‐Chayama Hiromi、Nelson Hayes C.、Aikata Hiroshi、Chayama Kazuaki
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: 28 Issue: 2 Pages: 400-409
- DOI
  10.1111/jvh.13441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07973
[Journal Article] Signal Activation of Hepatitis B Virus-Related Hepatocarcinogenesis by Up-regulation of SUV39h12020
- Author(s)
  Takeuchi Yasue、Tsuge Masataka、Tsushima Ken、Suehiro Yosuke、Fujino Hatsue、Ono Atsushi、Yamauchi Masami、Makokha Grace Naswa、Nakahara Takashi、Murakami Eisuke、Abe-Chayama Hiromi、Kawaoka Tomokazu、Miki Daiki、Imamura Michio、Aikata Hiroshi、Hayes C Nelson、Tateno Chise、Chayama Kazuaki
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 222 Issue: 12 Pages: 2061-2070
- DOI
  10.1093/infdis/jiaa317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07973
[Journal Article] ヒト肝細胞キメラマウスを用いたB型肝炎研究の最前線2019
- Author(s)
  柘植雅貴、茶山一彰
- Journal Title
  
  消化器・肝臓内科
  
  Volume: 6 Pages: 271-278
- Data Source
  KAKENHI-PROJECT-17KK0194
[Journal Article] Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection2019
- Author(s)
  Tsuge Masataka, Uchida Takuro, Walsh Kevin, Ishida Yuji, Tateno Chise, Kumar Upendra, Glenn Jeffrey, Koh Christopher, Heller Theo, Uprichard Susan, Dahari Harel, Chayama Kazuaki
- Journal Title
  
  Viruses
  
  Volume: 11 Issue: 3 Pages: 263-263
- DOI
  10.3390/v11030263
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07973, KAKENHI-PROJECT-17KK0194
[Journal Article] Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice2019
- Author(s)
  Tsushima K, Tsuge M, Hiraga N, Uchida T, Murakami E, Makokha GN, Kurihara M, Nomura Motonobu, Hiyama Y, Fujino H, Ono A, Nakahara T, Yamauchi M, Abe-Chayama H, Kawaoka T, Miki D, Imamura M, Aikata H, Hayes CN, Chayama K
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 7 Pages: 650-659
- DOI
  10.1007/s00535-019-01558-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07973, KAKENHI-PROJECT-17KK0194, KAKENHI-PROJECT-17H06269, KAKENHI-PROJECT-17K09446
[Journal Article] Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP2019
- Author(s)
  Makokha Grace Naswa、Abe-Chayama Hiromi、Chowdhury Sajeda、Hayes C. Nelson、Tsuge Masataka、Yoshima Tadahiko、Ishida Yuji、Zhang Yizhou、Uchida Takuro、Tateno Chise、Akiyama Rie、Chayama Kazuaki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 8462-8462
- DOI
  10.1038/s41598-019-44934-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07973, KAKENHI-PROJECT-17H06269, KAKENHI-PROJECT-17KK0194
[Journal Article] ヒト肝細胞キメラマウスを用いたB型肝炎研究の最前線2019
- Author(s)
  柘植雅貴、茶山一彰
- Journal Title
  
  消化器・肝臓内科
  
  Volume: 6 Pages: 271-278
- Data Source
  KAKENHI-PROJECT-18K07973
[Journal Article] Combinational use of2018
- Author(s)
  Matsumoto A, Nishiguchi S, Enomoto H, Kang JH, Tanaka Y, Shinkai N, Kurosaki M, Enomoto M, Kanda T, Yokosuka O, Yatsuhashi H, Nagaoka S, Okuse C, Kagawa T, Mine T, Takaguchi K, Saito S, Hino K, Ikeda F, Sakisaka S, Morihara D, Miyase S, Tsuge M, Chayama K, Hiramatsu N, Suzuki Y, Murata K, Tanaka E
- Journal Title
  
  J Gastroenterol
  
  Volume: 53 Issue: 2 Pages: 247-257
- DOI
  10.1007/s00535-017-1360-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09448, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-15H01803, KAKENHI-PROJECT-15K09002
[Journal Article] Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study2018
- Author(s)
  Tatsukawa Yumiko, Tsuge Masataka, Kawakami Yoshiiku, Murakami Eisuke, Kurihara Mio, Nomura Motonobu, Tsushima Ken, Uchida Takuro, Nakahara Takashi, Miki Daiki, Kawaoka Tomokazu, Abe-Chayama Hiromi, Imamura Michio, Aikata Hiroshi, Ochi Hidenori, Hayes C Nelson, Kawakami Hiroiku, Chayama Kazuaki
- Journal Title
  
  Antiviral Therapy
  
  Volume: 23 Issue: 8 Pages: 639-646
- DOI
  10.3851/imp3240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07973
[Journal Article] CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients2018
- Author(s)
  Nomura M, Tsuge M, Uchida To, Hiraga N, Kurihara M, Tsushima K, Fujino H, Nakahara T, Murakami E, Abe-Chayama H, Kawaoka T, Miki D, Hiramatsu A, Imamura M, Kawakami Y, Aikata H, Ochi H, Zhang Y, Makokha GN, Hayes CN, Tanaka S, Chayama K
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: 25 Issue: 12 Pages: 1555-1564
- DOI
  10.1111/jvh.12970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07973
[Journal Article] Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes2018
- Author(s)
  Tsuge M, Hiraga N, Zhang Y, Yamashita M, Sato O, Oka N, Shiraishi K, Izaki Y, Makokha GN, Uchida T, Kurihara M, Nomura M, Tsushima K, Nakahara T, Murakami E, Abe-Chayama H, Kawaoka T, Miki D, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Fujita T, Chayama K
- Journal Title
  
  Virology
  
  Volume: 525 Pages: 48-61
- DOI
  10.1016/j.virol.2018.08.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07973
[Journal Article] Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology.2017
- Author(s)
  Uchida T, Imamura M, Kan H, Hiraga N, Hayes CN, Tsuge M, Abe-Chayama H, Aikata H, Makokha GN, Miki D, Ochi H, Ishida Y, Tateno C, Chayama K.
- Journal Title
  
  J Gen Virol.
  
  Volume: 印刷中 Issue: 5 Pages: 1040-1047
- DOI
  10.1099/jgv.0.000726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26420796, KAKENHI-PROJECT-17K09427, KAKENHI-PROJECT-15K09002
[Journal Article] Persistent loss of HBV markers in serum without cellular immunity by combination of PEG-IFN plus ETV therapy in humanized mice2017
- Author(s)
  Uchida T, Imamura M, Hayes CN, Hiraga N, Kan H, Tsuge M, Abe-Chayama H, Zhang Y, Makokha GN, Aikata H, Miki D, Ochi H, Ishida Y, Tateno C, Chayama K
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 61 Issue: 9
- DOI
  10.1128/aac.00725-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09427, KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-16K19346
[Journal Article] Development of a novel site-specific pegylated interferon beta for antiviral therapy for chronic hepatitis B.2017
- Author(s)
  Tsuge M, Uchida T, Hiraga N, Kan H, Makokha GN, Abe-Chayama H, Miki D, Imamura M, Ochi H, Hayes CN, Shimozono R, Iwamura T, Narumi H, Suzuki T, Kainoh M, Taniguchi T, Chayama K.
- Journal Title
  
  Antimicrob Agents Chemother.
  
  Volume: 印刷中 Issue: 6 Pages: 61-61
- DOI
  10.1128/aac.00183-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26420796, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15K09002
[Journal Article] The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients.2017
- Author(s)
  Urabe A, Imamura M, Tsuge M, Kan H, Fujino H, Fukuhara T, Masaki K, Kobayashi T, Ono A, Nakahara T, Kawaoka T, Hiramatsu A, Kawakami Y, Aikata H, Hayes CN, Maki N, Ohdan H, Chayama K.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 52 Issue: 3 Pages: 366-375
- DOI
  10.1007/s00535-016-1240-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15293, KAKENHI-PROJECT-15K09002
[Journal Article] The prognosis of hepatitis B inactive carriers in Japan: a multicenter prospective study.2017
- Author(s)
  Taida T., Arai M., Kanda T., Hige S., Ueno Y., Imazeki F., Izumi N., Tanaka E., Shinkai N., Yoshioka K., Nakamoto Y., Nishiguchi S., Tsuge M., Abe M., Sata M., Yatsuhashi H., Ido A., Kita K., Azemoto R., Kitsukawa Y., Goto N. and Yokosuka O.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 52 Issue: 1 Pages: 113-122
- DOI
  10.1007/s00535-016-1229-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15H01803
[Journal Article] Elimination of HCV via a non-ISG-mediated mechanism by vaniprevir andBMS-788329 combination therapy in human hepatocyte chimeric mice.2016
- Author(s)
  Uchida T, Hiraga N, Imamura M, Yoshimi S, Kan H, Miyaki E, Tsuge M, Abe H, Hayes CN, Aikata H, Ishida Y, Tateno C, Ellis JD, Chayama K.
- Journal Title
  
  Virus Res.
  
  Volume: 213 Issue: 1 Pages: 62-68
- DOI
  10.1016/j.jinf.2015.09.038
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26420796, KAKENHI-PROJECT-15K15293, KAKENHI-PROJECT-15K09002
[Journal Article] Improvement of renal dysfunction in a patient with HCV-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report.2016
- Author(s)
  Tsuge M, Hiramatsu A, Shinohara F, Nakano N, Nakamura Y, Hatooka M, Morio K, Morio R, Kan H, Fujino H, Uchida T, Kobayashi T, Fukuhara T, Masaki K, Nakahara T, Ono A, Nagaoki Y, Miki D, Kawaoka T, Hiraga N, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Chayama K.
- Journal Title
  
  Hepatology Research
  
  Volume: 印刷中 Issue: 9 Pages: 944-948
- DOI
  10.1111/hepr.12629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09002
[Journal Article] Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection.2016
- Author(s)
  Tsuge M, Hiraga N, Uchida T, Kan H, Miyaki E, Masaki K, Ono A, Nakahara T, Abe-Chayama H, Zhang Y, Naswa MG, Kawaoka T, Miki D, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Chayama K.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09002
[Journal Article] Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection.2016
- Author(s)
  Tsuge M, Hiraga N, Uchida T, Kan H, Miyaki E, Masaki K, Ono A, Nakahara T, Abe-Chayama H, Zhang Y, Naswa MG, Kawaoka T, Miki D, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Chayama K.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: In press Issue: 11 Pages: 1073-1080
- DOI
  10.1007/s00535-016-1189-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860191, KAKENHI-PROJECT-15K15293, KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-16K19346
[Journal Article] A case of chronic inflammatory demyelinating polyradiculoneuropathy after treatment with pegylated interferon α-2a in a patient with chronic hepatitis B virus infection2016
- Author(s)
  Naito H., Takeda I., Segawa A., Tsuge M., Maruyama H. and Matsumoto M.
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 56 Issue: 10 Pages: 672-677
- DOI
  10.5692/clinicalneurol.cn-000888
- NAID
  130005250055
- ISSN
  0009-918X, 1882-0654
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09002
[Journal Article] de novo B型肝炎のインパクト2016
- Author(s)
  柘植雅貴、茶山一彰
- Journal Title
  
  医学のあゆみ
  
  Volume: 258 Pages: 1144-1146
- Data Source
  KAKENHI-PROJECT-15K09002
[Journal Article] Differences in serum microRNA profiles in hepatitis B and C virus infection.2015
- Author(s)
  Akamatsu S, Hayes CN, Tsuge M, Miki D, Akiyama R, Abe H, Ochi H, Hiraga N, Imamura M, Takahashi S, Aikata H, Kawaoka T, Kawakami Y, Ohishi W, Chayama K.
- Journal Title
  
  J Infect.
  
  Volume: 70 Issue: 3 Pages: 273-287
- DOI
  10.1016/j.jinf.2014.10.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26420796, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-26860536, KAKENHI-PROJECT-15K09002
[Journal Article] Factors associated with the effect of interferon-alpha sequential therapy in order to discontinue nucleoside/nucleotide analog treatment in patients with chronic hepatitis B.2015
- Author(s)
  Matsumoto A., Yatsuhashi H., Nagaoka S., Suzuki Y., Hosaka T., Tsuge M., Chayama K., Kanda T., Yokosuka O., Nishiguchi S., Saito M., Miyase S., Kang J.H., Shinkai N., Tanaka Y., Umemura T. and Tanaka E.
- Journal Title
  
  Hepatology Research
  
  Volume: 45 Issue: 12 Pages: 1195-1202
- DOI
  10.1111/hepr.12488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09002
[Journal Article] Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice.2015
- Author(s)
  Uchida T., Hiraga N., Imamura M., Tsuge M., Abe H., Hayes C.N., Aikata H., Ishida Y., Tateno C., Yoshizato K., Ohdan H., Murakami K. and Chayama K.
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 19 Pages: 10087-96
- DOI
  10.1128/jvi.01126-15
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-26420796
[Journal Article] Serum interleukin-6 associated with hepatocellular carcinoma risk: a nested case-control study2014
- Author(s)
  Waka Ohishi, John B. Cologne, Saeko Fujiwara, Gen Suzuki, Tomonori Hayashi, Yasuharu Niwa, Masazumi Akahoshi, Keiko Ueda, Masataka Tsuge, Kazuaki Chayama
- Journal Title
  
  International Journal of Cancer
  
  Volume: 134巻 Issue: 1 Pages: 154-163
- DOI
  10.1002/ijc.28337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590840, KAKENHI-PROJECT-24390162, KAKENHI-PROJECT-24791023, KAKENHI-PROJECT-25330039, KAKENHI-PROJECT-26670383
[Journal Article] Human microRNA hsa-miR-1231 suppresses hepatitis B virus replication by targeting core mRNA.2014
- Author(s)
  Kohno T, Tsuge M, Murakami E, Hiraga N, Abe H, Miki D, Imamura M, Ochi H, Hayes CN, Chayama K.
- Journal Title
  
  J Viral Hepat.
  
  Volume: 21 Issue: 4 Pages: 369-375
- DOI
  10.3851/imp2777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26420796, KAKENHI-PROJECT-15K09002
[Journal Article] Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients2013
- Author(s)
  Tsuge M., Murakami E., Imamura M., Abe H., Miki D., Hiraga N., Takahashi S., Ochi H., Nelson Hayes C., Ginba H., Matsuyama K., Kawakami H. and Chayama K
- Journal Title
  
  J Gastroenterol
  
  Volume: 48(10) Issue: 10 Pages: 1188-204
- DOI
  10.1007/s00535-012-0737-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791023
[Journal Article] Availability of monitoring serum HBV DNA plus RNA during nucleot(s)ide analogue therapy.2013
- Author(s)
  Tsuge M, Chayama K
- Journal Title
  
  Journal of gastroenterology
  
  Volume: 48(6) Issue: 6 Pages: 779-80
- DOI
  10.1007/s00535-013-0801-6
- NAID
  10031184069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791023
[Journal Article] Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B.2013
- Author(s)
  Arataki K, Hayes CN, Akamatsu S, Akiyama R, Abe H, Tsuge M, Miki D, Ochi H, Hiraga N, Imamura M, Takahashi S, Aikata H, Kawaoka T, Kawakami H, Ohishi W, Chayama K.
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 85(5) Issue: 5 Pages: 789-98
- DOI
  10.1002/jmv.23540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791023, KAKENHI-PROJECT-25670369
[Journal Article] Changes in mRNA expression of hypothalamic appetite-regulating peptides during different phases of lactation in rats2013
- Author(s)
  Suzuki Y,Nakahara K, Maruyama K, Okame R, Ensho T, Inoue Y,Murakami N.
- Journal Title
  
  J Mol Endocrinol
  
  Volume: 52 Issue: 1 Pages: 97-109
- DOI
  10.1016/j.bbrc.2013.10.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380173, KAKENHI-PROJECT-24658247, KAKENHI-PROJECT-24790701, KAKENHI-PROJECT-24790702, KAKENHI-PROJECT-24791023, KAKENHI-PROJECT-25670369
[Journal Article] Severe necroinflammatory reaction caused by natural killer by Fas/ FasL interaction and dendritic cells in human hepatocyte chimeric mouse2012
- Author(s)
  Okazaki A, Hiraga N, Imamura M, NelsonHayes C, Tsuge M, Takahashi S, AikataH, Abe H, Miki D, Ochi H, Tateno C, Yoshizato K, Ohdan H, Chayama K
- Journal Title
  
  Hepatology
  
  Volume: (in press) Issue: 2 Pages: 25651-25651
- DOI
  10.1002/hep.25651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390229, KAKENHI-PROJECT-22659147, KAKENHI-PROJECT-22790646, KAKENHI-PROJECT-24659368, KAKENHI-PROJECT-24791023
[Journal Article] ヒト肝細胞キメラマウスを用いた抗HBV 薬剤感受性評価と臨床への応用2012
- Author(s)
  柘植雅貴, 今村道雄, 茶山一彰
- Journal Title
  
  肝胆膵
  
  Volume: 65(4) Pages: 591-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791023
[Journal Article] HBV RT領域変異株におけるテノホビルの抗ウイルス効果の検討2012
- Author(s)
  柘植雅貴, 平賀伸彦, 茶山一彰
- Journal Title
  
  消化器内科
  
  Volume: 54(5) Pages: 575-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791023
[Journal Article] HBV RT領域変異株におけるテノホビルの抗ウイルス効果の検討2012
- Author(s)
  柘植雅貴、平賀伸彦、茶山一彰
- Journal Title
  
  消化器内科
  
  Volume: 54 (5) Pages: 575-538
- Data Source
  KAKENHI-PROJECT-24791023
[Journal Article] ヒト肝細胞キメラマウスを用いた抗HBV薬剤感受性評価と臨床への応用2012
- Author(s)
  柘植雅貴、今村道雄、茶山一彰
- Journal Title
  
  肝胆膵
  
  Volume: 65 (4) Pages: 591-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791023
[Journal Article] Hepatitis B Virus-Specific miRNAs and Argonaute2 Play a Role in the Viral Life Cycle2010
- Author(s)
  Hayes CN, Akamatsu S, Tsuge M, Miki D, Akiyama R, Abe H, et al
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 10 Pages: e47490-e47490
- DOI
  10.1371/journal.pone.0047490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659368, KAKENHI-PROJECT-24791023
[Patent] 高力価のB型肝炎ウイルスを産生する細胞およびその作製方法2015
- Inventor(s)
  柘植雅貴、茶山一彰
- Industrial Property Rights Holder
  柘植雅貴、茶山一彰
- Industrial Property Rights Type
  特許
- Filing Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] Analysis of HBsAg and cccDNA reduction by nucleotide analogue and pegylated interferon combination therapy2024
- Author(s)
  Masataka Tsuge
- Organizer
  APASL2024 in Kyoto
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] Alteration of gene expression after entecavir and pegylated interferon therapy in HBV infected chimeric mouse liver2023
- Author(s)
  Huarui Bao, Masataka Tsuge, Serami Murakami, Takuro Uchida, Atsushi Ono, C. Hayes Nelson, Shiro Oka
- Organizer
  International HBV meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] Evaluating the efficacy of pegylated IFN-λ and IFN-α treatments on HBV and HDV infections in humanized mice2023
- Author(s)
  Takuro Uchida, Sarah Duehren, Masataka Tsuge, Nobuhiko Hiraga, Abu Fahad Abbasi, Ohad Etzion, Jeffrey Glenn, Christopher Koh, Theo Heller, Scott J. Cotler, Kazuaki Chayama, Harel Dahari
- Organizer
  International HBV meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] Evaluating the efficacy of pegylated IFN-λ and IFN-α treatments on HBV and HDV infections in humanized mice2023
- Author(s)
  Sarah Duehren, Takuro Uchida, Masataka Tsuge, Nobuhiko Hiraga, Abu Fahad Abbasi, Ohad Etzion, Jeffrey Glenn, Christopher Koh, Theo Heller, Scott J. Cotler, Kazuaki Chayama, Harel Dahari
- Organizer
  AASLD 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] 核酸アナログ・PEG-IFN併用療法におけるHBsAg、cccDNA低下に関する検討2023
- Author(s)
  柘植雅貴、川上由育、岡　志郎
- Organizer
  第109回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] B型慢性肝疾患症例における核酸アナログ・ペグインターフェロン併用療法の長期的経過およびcccDNA低下に関する検討2023
- Author(s)
  小坂正成，藤野初江，柘植雅貴，山﨑慎太郎，矢野成樹，白根佑樹，上平祐輔，村上せらみ，三浦崚一，鳴戸謙輔，吉川ゆき，網岡慶，小川裕太郎，山岡賢治，藤井康智，内川慎介，大野敦司，中原隆志，村上英介，河岡友和，三木大樹，岡志郎
- Organizer
  日本抗ウイルス療法学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] Chronic hepatitis B2022
- Author(s)
  Masataka Tsuge
- Organizer
  Seminar in Anhui Medical University
- Invited
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] Hepatitis B Virus Upregulates TRAIL-R3 Expression in Hepatocytes Resulting in Escape From Both Cell Apoptosis and Suppression of HBV Replication by TRAIL2022
- Author(s)
  Yosuke Suehiro, Masataka Tsuge, Mio Kurihara, Takuro Uchida, Hatsue Fujino, Atsushi Ono, Masami Yamauchi, Grace Naswa Makokha, Takashi Nakahara, Eisuke Murakami, Hiromi Abe-Chayama, Tomokazu Kawaoka, Daiki Miki, Michio Imamura, Hiroshi Aikata, C. Nelson Hayes, Takashi Fujita, Kazuaki Chayama
- Organizer
  AASLD2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] 培養細胞、ヒト肝細胞キメラマウスを用いた肝炎ウイルス研究2022
- Author(s)
  柘植雅貴
- Organizer
  Tohoku Hepatology Research Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] HBV感染におけるTRAIL-R3発現亢進による細胞内免疫回避機構の解明2022
- Author(s)
  末廣洋介, 柘植雅貴, 岡　志郎
- Organizer
  第44回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] KIF4A, a new host factor required for surface localization of NTCP, and HBV/HDV infection2021
- Author(s)
  Gad SA, Sugiyama M, Tsuge M, Wakae K, Fukano K, Watanabe N, Kato T, Murayama A, Li Y, Shoji I, Shimotohno K, Chayama K, Muramatsu M, Wakita T, Nozaki T, Aly HH.
- Organizer
  2021 International HBV Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] Entecavir投与中のB型慢性肝炎患者における血清オートタキシン濃度の変化と肝発がん予測への有用性2021
- Author(s)
  藤野初江、柘植雅貴、茶山一彰
- Organizer
  第57回日本肝臓学会総会パネルディスカッション
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] エンテカビル治療B型慢性肝炎症例における肝発癌・HBs抗原低下と血清サイトカインとの関連2021
- Author(s)
  柘植雅貴、竹内泰江、茶山一彰
- Organizer
  第107回日本消化器病学会総会シンポジウム
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] HBV感染によるヒストン修飾と発癌との関連の検討2021
- Author(s)
  柘植雅貴、竹内泰江、茶山一彰
- Organizer
  第57回日本肝臓学会総会ワークショップ
- Data Source
  KAKENHI-PROJECT-21K08006
[Presentation] 新規PEG-IFNβ製剤を用いた抗HBV効果の検討と抗ウイルス効果向上の試み2020
- Author(s)
  竹内泰江，柘植雅貴，茶山一彰
- Organizer
  第56回日本肝臓学会総会　シンポジウム5
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 核酸アナログ投与B型慢性肝炎症例に対するHBIG治療成績と奏効に寄与する因子の検討2020
- Author(s)
  柘植雅貴、三木大樹、茶山一彰
- Organizer
  第56回日本肝臓学会総会パネルディスカッション2
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] エンテカビル治療中のHBV関連マーカーの変化に及ぼす血清サイトカインの影響2020
- Author(s)
  竹内泰江，柘植雅貴，茶山一彰
- Organizer
  第106回日本消化器病学会総会シンポジウム6
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] HBs抗原陰性化を目指したB型肝炎治療～実臨床成績、基礎研究の現状～2020
- Author(s)
  柘植雅貴
- Organizer
  JDDW2020 ブレックファーストセミナー19
- Invited
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] IL8の発現制御によるHBVに対するIFN治療改善の可能性2020
- Author(s)
  柘植雅貴、津島健、茶山一彰
- Organizer
  第106回日本消化器病学会総会パネルディスカッション5
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 核酸アナログ・ペグインターフェロン併用療法におけるHBs低下に寄与する因子の検討2019
- Author(s)
  藤野初江、柘植雅貴、寺岡雄吏、盛生慶、大野敦司、中原隆志、村上英介、河岡友和、三木大樹、平松憲、今村道雄、相方浩、茶山一彰
- Organizer
  第43回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 症例から学ぶ　B型肝炎の診断・治療の最前線2019
- Author(s)
  柘植雅貴
- Organizer
  第55回日本肝臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 症例から学ぶ　B型肝炎の診断・治療の最前線2019
- Author(s)
  柘植雅貴
- Organizer
  第55回日本肝臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17KK0194
[Presentation] Analysis of the association between HBV infection and long-term trends in intrahepatic gene expression.2019
- Author(s)
  Masataka Tsuge, Ken Tsushima, Nobuhiko Hiraga, Takuro Uchida, Michio Imamura, C. Hayes Nelson, Harel Dahari, Susan L. Uprichard, Kazuaki Chayama
- Organizer
  International HBV meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0194
[Presentation] Investigation of infectivity of serum-derived HBV from patients and human hepatocyte chimeric mouse to HepG2/NTCP cells.2019
- Author(s)
  Hatsue Fujino, Miko Namba, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, C. Hayes Nelson, Michio Imamura, Hiroshi Aikata, Kazuaki Chayama
- Organizer
  International HBV meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0194
[Presentation] Serum atutotaxin levels is useful to evaluate fibrosis during entecavir therapy and to predict the development of hepatocellular carcinoma in patients with chronic hepatitis B.2019
- Author(s)
  Hatsue Fujino, Kei Morio, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, C. Hayes Nelson, Michio Imamura, Hiroshi Aikata, Kazuaki Chayama
- Organizer
  International HBV meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0194
[Presentation] Analysis of the association between HBV infection and long-term trends in intrahepatic gene expression.2019
- Author(s)
  Masataka Tsuge, Ken Tsushima, Nobuhiko Hiraga, Takuro Uchida, Michio Imamura, C. Hayes Nelson, Harel Dahari, Susan L. Uprichard, Kazuaki Chayama
- Organizer
  International HBV meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 核酸アナログ・ペグインターフェロン併用療法におけるHBs低下に寄与する因子の検討2019
- Author(s)
  藤野初江、柘植雅貴、寺岡雄吏、盛生慶、大野敦司、中原隆志、村上英介、河岡友和、三木大樹、平松憲、今村道雄、相方浩、茶山一彰
- Organizer
  第43回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-17KK0194
[Presentation] Serum atutotaxin levels is useful to evaluate fibrosis during entecavir therapy and to predict the development of hepatocellular carcinoma in patients with chronic hepatitis B.2019
- Author(s)
  Hatsue Fujino, Kei Morio, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, C. Hayes Nelson, Michio Imamura, Hiroshi Aikata, Kazuaki Chayama
- Organizer
  International HBV meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 核酸アナログ・ペグインターフェロン併用療法におけるHBs低下に寄与する因子の検討2019
- Author(s)
  柘植雅貴、辰川裕美子、茶山一彰
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17KK0194
[Presentation] Investigation of infectivity of serum-derived HBV from patients and human hepatocyte chimeric mouse to HepG2/NTCP cells.2019
- Author(s)
  Hatsue Fujino, Miko Namba, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, C. Hayes Nelson, Michio Imamura, Hiroshi Aikata, Kazuaki Chayama
- Organizer
  International HBV meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic HBV infection.2019
- Author(s)
  Masataka Tsuge, Motonobu Nomura, Takuro Uchida, Hiromi Abe-Chayama, Daiki Miki, Michio Imamura, Hiroshi Aikata, Grace Naswa Makokha, C. Nelson Hayes, Kazuaki Chayama
- Organizer
  7th Japan-Taiwan-Korea HBV Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0194
[Presentation] 2.核酸アナログ・ペグインターフェロン併用療法におけるHBs低下に寄与する因子の検討2019
- Author(s)
  柘植雅貴、辰川裕美子、茶山一彰
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic HBV infection.2019
- Author(s)
  Masataka Tsuge, Motonobu Nomura, Takuro Uchida, Hiromi Abe-Chayama, Daiki Miki, Michio Imamura, Hiroshi Aikata, Grace Naswa Makokha, C. Nelson Hayes, Kazuaki Chayama
- Organizer
  7th Japan-Taiwan-Korea HBV Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 核酸アナログ治療後のペグインターフェロン治療におけるHBs低下に寄与する因子の検討2018
- Author(s)
  柘植雅貴、辰川裕美子、茶山一彰
- Organizer
  JDDW2018
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 脂質代謝と肝炎ウイルス増殖との関連2018
- Author(s)
  柘植雅貴
- Organizer
  Up To Date Seminar for Researchers
- Invited
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] B型肝炎ウイルス（HBV）関連肝疾患に対する肝移植とHBV再感染の解析2018
- Author(s)
  柘植雅貴、今村道雄、茶山一彰
- Organizer
  第104回日本消化器学会総会
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 新規ペグ化インターフェロンβによるB型肝炎ウイルスに対する抗ウイルス効果の検討2018
- Author(s)
  柘植雅貴、内田宅郎、茶山一彰
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] B型肝炎治療の現状と新規治療薬開発の動向2018
- Author(s)
  柘植雅貴
- Organizer
  広島肝炎ウイルスセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] The influence of histone methyltransferase SUV39h1 on hepatitis B virus related hepatocarcinogenesis2018
- Author(s)
  Ken Tsushima, Masataka Tsuge, Takuro Uchida, Michio Imamura, Mitsutaka Osawa, Hiromi Abe-Chayama, Grace Naswa Makokha, Hiroshi Aikata, Kazuaki Chayama
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07973
[Presentation] 1.B型肝炎ウイルス（HBV）感染に伴う肝細胞内IL8発現亢進と細胞内インターフェロン反応性の検討2017
- Author(s)
  柘植雅貴、内田宅郎、茶山一彰
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 3.核酸アナログ治療併用の有無によるインターフェロン治療効果の検討2017
- Author(s)
  柘植雅貴、川上由育、茶山一彰
- Organizer
  第21回日本肝臓学大会
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 5.核酸アナログ治療例に対するペグインターフェロン治療とHBs低下に関する検討2017
- Author(s)
  柘植雅貴、川上由育、内川慎介、児玉健一郎、西田祐乃、稲垣有希、盛生　慶、中原隆志、村上英介、河岡友和、平松　憲、今村道雄、相方　浩、川上広育、茶山一彰
- Organizer
  第42回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 4.Hepatitis B virus up-regulates IL8 expression via endoplasmic reticulum stress and leads to suppress interferon responsiveness.2017
- Author(s)
  Tsuge M, Hiraga N, Uchida T, Murakami E, Abe-Chayama H, Miki D, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Chayama K
- Organizer
  AASLD（米国肝臓学会）2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 2.B型慢性肝疾患に対するエンテカビル治療と血清サイトカインの変化2017
- Author(s)
  柘植雅貴、栗原美緒、茶山一彰
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] B型肝炎ウイルス感染に伴うヒト肝細胞内遺伝子の発現変化の解析2016
- Author(s)
  柘植雅貴、平賀伸彦、茶山一彰
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉県幕張
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] ヒト肝細胞キメラマウスを用いたB型肝炎ウイルス遺伝子型による感染肝細胞内遺伝子発現変化の検討2016
- Author(s)
  柘植雅貴、平賀伸彦、内田宅郎、菅宏美、阿部弘美、三木大樹、河岡友和、今村道雄、相方浩、越智秀典、茶山一彰
- Organizer
  臨床分子医学会2016
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 核酸アナログ投与B型慢性肝炎症例に対するHBIG投与の有効性2016
- Author(s)
  柘植雅貴、川上由育、茶山一彰
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉県幕張
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] Evaluation of antiviral effects of a novel site-specific pegylated interferon beta using humanized mouse model2016
- Author(s)
  Masataka Tsuge, Takuro Uchida, Hiromi Kan, Hiromi Abe, Daiki Miki, Michio Imamura, Hidenori Ochi, C Nelson Hayes, Reiko Shimozono, Tomokatsu Iwamura, Hideki Narumi, Tomohiko Suzuki, Mie Kainoh, Tadatsugu Taniguchi, Kazuaki Chayama
- Organizer
  AASLD2016
- Place of Presentation
  米国、ボストン
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] ヒト肝細胞キメラマウスを用いたB型肝炎ウイルス遺伝子型による感染肝細胞内遺伝子発現変化の検討2016
- Author(s)
  柘植雅貴、内田宅郎、菅宏美、阿部弘美、三木大樹、河岡友和、平賀伸彦、今村道雄、相方浩、越智秀典、茶山一彰
- Organizer
  第12回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島県広島市
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] HBV genotypeに伴う核酸アナログ感受性に関する検討2016
- Author(s)
  柘植雅貴、村上英介、茶山一彰
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 核酸アナログ先行投与によるインターフェロン反応性の改善2016
- Author(s)
  柘植雅貴、森奈美、長沖祐子、河岡友和、平松憲、今村道雄、川上由育、相方浩、辻恵二、川上広育、茶山一彰
- Organizer
  DDW2016
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] HBV RNA量を用いた核酸アナログ中止後再燃予測2015
- Author(s)
  柘植雅貴、川上広育、茶山一彰
- Organizer
  第42回日本肝臓学会西部会（パネルディスカッション）
- Place of Presentation
  名古屋
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] B型肝炎治療の現状2015
- Author(s)
  柘植雅貴
- Organizer
  JDDW 2015（ランチョンセミナー）
- Place of Presentation
  東京
- Year and Date
  2015-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] HBV genotypeと核酸アナログの抗ウイルス効果2015
- Author(s)
  柘植雅貴、村上英介、平賀伸彦、阿部弘美、今村道雄、秋田智之、田中純子、茶山一彰
- Organizer
  第11回広島肝臓プロジェクト研究センターシンポジウム（一般演題）
- Place of Presentation
  広島
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] HBV感染に伴うmicroRNA発現変化と miRNAによるHBV複製制御2015
- Author(s)
  柘植雅貴、平賀伸彦、村上英介、阿部弘美、三木大樹、河岡友和、平松　憲、今村道雄、川上由育、相方　浩、越智秀典、茶山一彰
- Organizer
  第51回日本肝臓学会総会（一般演題）
- Place of Presentation
  熊本
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 当院におけるHBVキャリアのHBs抗原陰性化と肝発癌に関する検討2015
- Author(s)
  村上英介、柘植雅貴、茶山一彰
- Organizer
  第101回日本消化病学会総会（シンポジウム）
- Place of Presentation
  仙台
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 核酸アナログ先行投与によるインターフェロン反応性の変化2015
- Author(s)
  柘植雅貴、平賀伸彦、茶山一彰
- Organizer
  第101回日本消化病学会総会（ワークショップ）
- Place of Presentation
  仙台
- Year and Date
  2015-04-14
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] HBV genotype C感染例におけるHBs抗原消失に関する検討2015
- Author(s)
  柘植雅貴、村上英介、茶山一彰
- Organizer
  JDDW 2015（ワークショップ）
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] Difference of intracellular responses by HBV genotype A and C infection in humanized mouse model2015
- Author(s)
  Masataka Tsuge, Nobuhiko Hiraga, Hiromi Abe, Daiki Miki, Michio Imamura, Hidenori Ochi, C Nelson Hayes, Kazuaki Chayama
- Organizer
  AASLD2016（ポスター）
- Place of Presentation
  米国（サンフランシスコ）
- Year and Date
  2015-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] 核酸アナログ中止例における HBVコア蛋白のアミノ酸変異に関する解析2015
- Author(s)
  村上英介、柘植雅貴、内田宅郎、菅　宏美、柾木慶一、本田洋士、中原隆志、大野敦司、平賀伸彦、河岡友和、平松　憲、今村道雄、相方　浩、茶山一彰、川上広育
- Organizer
  第51回日本肝臓学会総会（一般演題）
- Place of Presentation
  熊本
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K09002
[Presentation] ヒト肝細胞キメラマウスを用いたHBV・HCV 感染に伴うヒト肝細胞内遺伝子発現変化の解析2013
- Author(s)
  柘植雅貴, 平賀伸彦, 今村道雄, 越智秀典, 高橋祥一, 茶山一彰
- Organizer
  第50回日本臨床分子医学会
- Place of Presentation
  東京
- Year and Date
  2013-04-12
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] B型肝炎における治療・診断の最近の話題2013
- Author(s)
  柘植雅貴
- Organizer
  第30回広島県医学検査学会　ランチョンセミナー
- Place of Presentation
  呉市
- Invited
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] Antiviral effect of tenofovir disoproxil fumarate on drug-resistant HBV clones and different susceptibility between HBV genotype A and C.2013
- Author(s)
  Eisuke Murakami, Masataka Tsuge, Nobuhiko Hiraga, Tomokazu Kawaoka, Atsushi Ohno, Takashi Nakahara, Daiki Miki, Hiromi Abe, Michio Imamura, Hiroshi Aikata, Hidenori Ochi, C Nelson Hayes, Chise Tateno, Katsutoshi Yoshizato, Kazuaki Chayama.
- Organizer
  64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  ワシントン（USA）
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性B型肝炎ウイルスに対するテノホビルの抗ウイルス効果と Genotypeによる相違の検討2013
- Author(s)
  村上英介、柘植雅貴、茶山一彰
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] ヒト肝細胞キメラマウスを用いたHBV・HCV感染に伴うヒト肝細胞内遺伝子発現変化の解析2013
- Author(s)
  柘植雅貴、平賀伸彦、今村道雄、越智秀典、高橋祥一、茶山一彰
- Organizer
  第50回日本臨床分子医学会　ポスター
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性B 型肝炎ウイルスに対するテノホビルの抗ウイルス効果の検討2013
- Author(s)
  村上英介, 柘植雅貴, 平賀伸彦, 阿部弘美, 大野敦司, 本田洋士, 河岡友和, 三木大樹, 今村道雄, 相方浩, 高橋祥一, 越智秀典, 茶山一彰
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2013-06-07
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] Monitoring serum HBV RNA is useful for predicting rebound of hepatitis after the discontinuation of nucleotide analogue therapy in chronic hepatitis B patients2013
- Author(s)
  Masataka Tsuge, Eisuke Murakami, Michio Imamura, Hiromi Abe, Daiki Miki, Nobuhiko Hiraga, Hidenori Ochi, C. Nelson Hayes, Hiroyuki Ginba, Kazuhiro Matsuyama, Hiroiku Kawakami, Kazuaki Chayama
- Organizer
  64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2013)
- Place of Presentation
  ワシントンDC, USA
- Year and Date
  2013-11-03
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] HBV感染に伴うヒト肝細胞内免疫応答の変化2013
- Author(s)
  柘植雅貴、高橋祥一、茶山一彰
- Organizer
  第49回日本肝臓学会総会　シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 当院におけるB 型急性肝炎の解析2013
- Author(s)
  占部綾子, 柘植雅貴, 茶山一彰
- Organizer
  第40回日本肝臓学会西部会
- Place of Presentation
  岐阜
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性HBV に対する核酸アナログ製剤の抗ウイルス効果の検討とgenotype による相違2013
- Author(s)
  柘植雅貴, 村上英介, 平賀伸彦, 阿部弘美, 今村道雄, 茶山一彰
- Organizer
  第9回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性HBVに対するテノホビルの抗ウイルス効果とgenotypeによる相違2013
- Author(s)
  柘植雅貴、村上英介、茶山一彰
- Organizer
  第17回日本肝臓学会大会　パネルディスカッション
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] B型肝炎ウイルス感染と抗ウイルス療法2013
- Author(s)
  柘植雅貴
- Organizer
  Digestive Disease Renaissance
- Place of Presentation
  大阪
- Year and Date
  2013-10-19
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] B型肝炎治療におけるHBV 関連マーカーの臨床的意義2013
- Author(s)
  柘植雅貴
- Organizer
  アボット肝疾患セミナー広島
- Place of Presentation
  広島
- Year and Date
  2013-11-14
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 当院における核酸アナログ製剤の治療効果の解析2013
- Author(s)
  村上英介、柘植雅貴、菅　宏美、藤野初江、小林知樹、福原崇之、柾木慶一、大野敦司、苗代典昭、中原隆志、本田洋士、宮木大輔、占部綾子、横山聡栄、河岡友和、三木大樹、平賀伸彦、平松　憲、今村道雄、兵庫秀幸、川上由育、相方　浩、高橋祥一、茶山一彰
- Organizer
  第17回日本肝臓学会大会　ポスター
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性B型肝炎ウイルスに対するテノホビルの抗ウイルス効果の検討2013
- Author(s)
  村上英介、柘植雅貴、平賀伸彦、阿部弘美、大野敦司、本田洋士、河岡友和、三木大樹、今村道雄、相方　浩、高橋祥一、越智秀典、茶山一彰
- Organizer
  第49回日本肝臓学会総会　一般演題
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] Monitoring serum HBV RNA is useful for predicting rebound of hepatitis after the discontinuation of nucleotide analogue therapy in chronic hepatitis B patients.2013
- Author(s)
  Masataka Tsuge, Eisuke Murakami, Michio Imamura, Hiromi Abe, Daiki Miki, Nobuhiko Hiraga, Hidenori Ochi, C. Nelson Hayes, Hiroyuki Ginba, Kazuhiro Matsuyama, Hiroiku Kawakami, Kazuaki Chayama.
- Organizer
  64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  ワシントン（USA）
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性HBV に対するテノホビルの抗ウイルス効果とgenotype による相違2013
- Author(s)
  柘植雅貴, 村上英介, 茶山一彰
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性HBVに対する核酸アナログ製剤の抗ウイルス効果の検討とgenotypeによる相違2013
- Author(s)
  柘植雅貴、村上英介、平賀伸彦、阿部弘美、今村道雄、茶山一彰
- Organizer
  第9回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] HBV 感染に伴うヒト肝細胞内免疫応答の変化2013
- Author(s)
  柘植雅貴, 高橋祥一, 茶山一彰
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2013-06-07
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] Th1/2 ratio was associated with anti-viral effects of sequential therapy with lamivudine and interferon-α in HBe antigen-positive chronic hepatitis B patients2013
- Author(s)
  Nami Mori, Masataka Tsuge, Yoshiiku Kawakami, Hiroiku Kawakami, Kazuaki Chayama
- Organizer
  64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2013)
- Place of Presentation
  ワシントンDC, USA
- Year and Date
  2013-11-03
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 当院におけるB型急性肝炎の解析2013
- Author(s)
  占部綾子、柘植雅貴、茶山一彰
- Organizer
  第40回日本肝臓学会西部会　ワークショップ
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] B型肝炎治療におけるHBV関連マーカーの臨床的意義2013
- Author(s)
  柘植雅貴
- Organizer
  アボット肝疾患セミナー広島 2013
- Place of Presentation
  広島
- Invited
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] Antiviral effect of tenofovir disoproxil fumarate on drug-resistant HBV clones and different susceptibility between HBV genotype A and C2013
- Author(s)
  Eisuke Murakami, Masataka Tsuge, Nobuhiko Hiraga, Tomokazu Kawaoka, Atsushi Ohno, Takashi Nakahara, Daiki Miki, Hiromi Abe, Michio Imamura, Hiroshi Aikata, Hidenori Ochi, C Nelson Hayes, Chise Tateno, Katsutoshi Yoshizato, Kazuaki Chayama
- Organizer
  64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2013)
- Place of Presentation
  ワシントンDC, USA
- Year and Date
  2013-11-03
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 当院における核酸アナログ製剤の治療効果の解析2013
- Author(s)
  村上英介, 柘植雅貴, 菅宏美, 藤野初江, 小林知樹, 福原崇之, 柾木慶一, 大野敦司, 苗代典昭, 中原隆志, 本田洋士, 宮木大輔, 占部綾子, 横山聡栄, 河岡友和, 三木大樹, 平賀伸彦, 平松憲, 今村道雄, 兵庫秀幸, 川上由育, 相方浩, 高橋祥一, 茶山一彰
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] Th1/2 ratio was associated with anti-viral effects of sequential therapy with lamivudine and interferon-α in HBe antigen-positive chronic hepatitis B patients.2013
- Author(s)
  Nami Mori, Masataka Tsuge, Yoshiiku Kawakami, Hiroiku Kawakami, Kazuaki Chayama.
- Organizer
  64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  ワシントン（USA）
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 当院におけるB 型慢性肝炎に対するインターフェロン治療効果の検討2012
- Author(s)
  小林知樹, 柘植雅貴, 福原崇之, 柾木慶一, 苗代典昭, 中原隆志, 本田洋士, 宮木大輔, 長沖祐子, 河岡友和, 高木慎太郎 , 平松憲, 今村道雄, 川上由育, 兵庫秀幸, 相方浩, 高橋祥一, 茶山一彰
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-10
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] HBV 薬剤耐性変異株に対するテノホビルの抗ウイルス効果2012
- Author(s)
  柘植雅貴, 今村道雄, 茶山一彰
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性HBVに対する核酸アナログの抗ウイルス効果2012
- Author(s)
  柘植雅貴
- Organizer
  Hepatology Meeting in Japan 2012
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 薬剤耐性HBV に対する核酸アナログの抗ウイルス効果2012
- Author(s)
  柘植雅貴
- Organizer
  Hepatology Meeting in Japan 2012
- Place of Presentation
  東京
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] HBV薬剤耐性変異株に対するテノホビルの抗ウイルス効果2012
- Author(s)
  柘植雅貴、今村道雄、茶山一彰
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] 当院におけるB型慢性肝炎に対するインターフェロン治療効果の検討2012
- Author(s)
  小林知樹、柘植雅貴、茶山一彰
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24791023
[Presentation] HBV既往感染者に対する血液悪性疾患化学療法時の核酸アナログ製剤によるHBV 再活性化予防についての検討2012
- Author(s)
  村上英介, 柘植雅貴, 今村道雄, 小林知樹, 福原崇之, 柾木慶一, 苗代典昭, 中原隆志, 本田洋士, 宮木大輔, 長沖祐子, 河岡友和, 高木慎太郎, 平賀伸彦, 平松憲, 相方浩, 高橋祥一, 茶山一彰
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-24791023

1. ABE Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
2. IMAMURA Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. KAZUMOTO Murata

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. OHISHI Waka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. KONDO Yasuteru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. WATANABE Tsunamasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 茶山一彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 三木大樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. アリフセインハッサン

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 吉田理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. ZHANG YIZHOU

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中原桂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsuge Masataka 柘植 雅貴

TSUGE MASATAKA 柘植 雅貴

Research Projects

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Co-Researchers

Analysis of hepatocarcinogenesis in hepatocytes with hepatitis B virus infectionPrincipal Investigator

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Analysis of immune response mechanisms of CTL and NK cells in HBV infection HBV infectionPrincipal Investigator

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Association analysis between the suppression of interferon responsiveness by HBV infection and changes of gene expression in human hepatocytesPrincipal Investigator

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Analyses of antiviral mechanisms by interferon treatment on hepatitis B virus replicationPrincipal Investigator

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Analysis of mechanisms for suppressing interferon responsiveness by chronic hepatitis B virus infectionPrincipal Investigator

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Basic research for clarifing the phathologic characteristics with HBV genotype A infectionPrincipal Investigator

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[Book] 専門医のための消化器病学 第3版2021

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[Book] 「HBV の感染実験系」Hepatology Practice 第1巻 B型肝炎の診療を極める2013

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[Book] 「B型肝炎, D型肝炎」カラー版 消化器病学2013

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[Book] Hepatology Practice 第1巻 B型肝炎の診療を極める2013

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[Book] カラー版 消化器病学2013

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[Journal Article] Acute liver injury in a non-alcoholic fatty liver disease patient with chloroform exposure: a case report2023

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[Journal Article] Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics2023

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[Journal Article] Factors for the recurrence of hepatocellular carcinoma after hepatic resection2023

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Tsuge Masataka 柘植雅貴

TSUGE MASATAKA 柘植雅貴

[Book] 専門医のための消化器病学第3版2021

[Book] 「B型肝炎, D型肝炎」カラー版消化器病学2013

[Book] Hepatology Practice 第1巻　B型肝炎の診療を極める2013

[Book] カラー版　消化器病学2013