Akanuma Takashi 赤沼啓志

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AKANUMA Takashi 赤沼啓志

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Researcher Number	50450721
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2019: 慶應義塾大学, 医学部(信濃町), 助教 2015: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 2010 – 2013: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 2010: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 研究員 2008 – 2009: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 特別協力研究員
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related / Biology of Cells to Organisms, and related fields / Cell biology Except Principal Investigator Circulatory organs internal medicine / Developmental biology / Biological Sciences
Keywords	Principal Investigator ライブイメージング / ゼブラフィッシュ / 形 / 細胞分化 / T細胞 / 免疫 / 非遺伝的 / 定量解析 / 発生・分化 / ノックイン … More / ゲノム編集 / 運命決定 / 数理モデル / 確率 / オランダ / 国際研究者交流 / 拡散 / 非対称分裂 / ばらつき … More Except Principal Investigator 体節 / 脊椎動物 / 発生 / シグナル伝達 / 遺伝子 / 発生・分化 / 組織再生 / 血管内皮細胞 / Pcolce-1 / sFRP2 / 細胞老化 / 細胞内代謝 / 血管形成 / 線維芽細胞 / 線維化 / 心筋梗塞 / 分子心臓病態学 / ノックアウト / 変異体 / 転写制御 / 咽頭弓 / 形態形成 / 転写調節 / 発現制御 / 細胞・組織 / 細胞外環境 / 翻訳後修飾 / 脂質修飾 Less

細胞間相互作用と微小環境がもたらす免疫細胞分化に関する研究Principal Investigator
- Principal Investigator
  
  赤沼啓志
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Keio University
History of cell shape changes and cell-fate determination in asymmetric divisionPrincipal Investigator
- Principal Investigator
  
  Akanuma Takashi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biology of Cells to Organisms, and related fields
- Research Institution
  Keio University
The mechanism of shape-dependent stochastic asymmetric cell divisionPrincipal Investigator
- Principal Investigator
  
  AKANUMA Takashi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Nara Institute of Science and Technology
Integrative approaches toward the development of next-generation therapeutics for myocardial infarction
- Principal Investigator
  
  Thomas N. Sato
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Advanced Telecommunications Research Institute International
  Nara Institute of Science and Technology
Molecular mechanism underlying metameric morphogenesis
- Principal Investigator
  
  TAKADA Shinji
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Developmental biology
- Research Institution
  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設)
  National Institutes of Natural Sciences Okazaki Research Facilities
Movement and function of secreted signaling proteins in the extracellular environment
- Principal Investigator
  
  TAKADA Shinji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institutes of Natural Sciences Okazaki Research Facilities

All 2018 2017 2016 2011 2007

All Journal Article Presentation

[Journal Article] Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy.2018
- Author(s)
  Taisuke Kondo Yuki Imura Shunsuke Chikuma Sana Hibino Setsuko Omata‐Mise Makoto Ando Takashi Akanuma Mana Iizuka Ryota Sakai Rimpei Morita Akihiko Yoshimura
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 7 Pages: 2130-2140
- DOI
  10.1111/cas.13648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15290, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-16K09867, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-17K19398, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-16H05178
[Journal Article] Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications2017
- Author(s)
  Iizuka-Koga Mana、Nakatsukasa Hiroko、Ito Minako、Akanuma Takashi、Lu Qianjin、Yoshimura Akihiko
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 83 Pages: 113-121
- DOI
  10.1016/j.jaut.2017.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19398, KAKENHI-PROJECT-17K18092, KAKENHI-PROJECT-15J03260, KAKENHI-PROJECT-16J07704
[Journal Article] Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation2017
- Author(s)
  Someya Kazue、Nakatsukasa Hiroko、Ito Minako、Kondo Taisuke、Tateda Kenn-ichi、Akanuma Takashi、Koya Ikuko、Sanosaka Tsukasa、Kohyama Jun、Tsukada Yu-ichi、Takamura-Enya Takeji、Yoshimura Akihiko
- Journal Title
  
  International Immunology
  
  Volume: 29 Issue: 8 Pages: 365-375
- DOI
  10.1093/intimm/dxx049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00562, KAKENHI-PROJECT-16K15292, KAKENHI-PROJECT-17K19398, KAKENHI-PLANNED-25112008, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J03260, KAKENHI-PROJECT-15J07468
[Journal Article] Negative Regulation of Cytokine Signaling in Immunity2017
- Author(s)
  Yoshimura Akihiko、Ito Minako、Chikuma Shunsuke、Akanuma Takashi、Nakatsukasa Hiroko
- Journal Title
  
  Cold Spring Harbor Perspectives in Biology
  
  Volume: - Issue: 7 Pages: a028571-a028571
- DOI
  10.1101/cshperspect.a028571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19398, KAKENHI-PROJECT-15J03260
[Journal Article] Memory of cell shape biases stochastic fate decision-making despite mitotic rounding2016
- Author(s)
  Akanuma, T., Chen, C., Sato, T., Merks, R.M.H., Sato, T.N.
- Journal Title
  
  Nature Communications
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22229007
[Journal Article] Paf1 complex homologes are required for Notch-regulated transcription during somite segmentation2007
- Author(s)
  Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., & Takada, S.
- Journal Title
  
  EMBO Rep
  
  Volume: 8 Pages: 858-863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18107006
[Journal Article] Paf1 complex homologes are required for Notch-regulated transcription du ring somite segmentation2007
- Author(s)
  Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., & Takada, S.
- Journal Title
  
  EMBO Rep 8
  
  Pages: 858-863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18107006
[Journal Article] Paf1 complex homologes are required for Notch-regulated transcription during somite segmentation.2007
- Author(s)
  Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., Takada, S.
- Journal Title
  
  EMBO Rep 8
  
  Pages: 858-863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17082012
[Journal Article] Paf1 complexhomologes are required for Notch-regulated transcription during somite segmentation2007
- Author(s)
  Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., Takada, S.
- Journal Title
  
  EMBO Rep 8
  
  Pages: 858-863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18107006
[Journal Article] Pafl complex homologes are required for Notch-regulated transcription during somite segmentation2007
- Author(s)
  Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., &Takada. S.
- Journal Title
  
  EMBO Rep 8
  
  Pages: 858-863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17082012
[Presentation] In vivo imaging of immune cells using transgenic zebrafish2018
- Author(s)
  Takashi Akanuma, Akihiko Yoshimura
- Organizer
  日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K19398
[Presentation] Jagged/Notch directs epithelial reorganization and assembly of Fibronectin during pharyngeal pouch morphogenesis2011
- Author(s)
  Hiroyuki Tsunokuni, Takashi Akanuma, Shinji Takada
- Organizer
  The 7th European Zebrafish Meeting
- Place of Presentation
  英国、Edingburgh
- Year and Date
  2011-07-07
- Data Source
  KAKENHI-PROJECT-18107006

1. TAKADA Shinji (60206753)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. KOSHIDA Sumito (40342638)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. TAKADA Ritsuko (40450720)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. YABE Taijiro (30470074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. CHEN Quihong

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OHKUBO Tadashi (10450719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAWAMURA Akinori (10466691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. Thomas N. Sato (60548759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. HOSOKAWA Yoichiroh (20448088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UTSUMI Hideko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAHASHI Jun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUNOKUNI Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. WANGLAR Chimwar

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MERKS Roeland M. H.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKAMURA Takeji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 近藤泰介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akanuma Takashi 赤沼 啓志

AKANUMA Takashi 赤沼 啓志

Research Projects

Research Products

Co-Researchers

細胞間相互作用と微小環境がもたらす免疫細胞分化に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

History of cell shape changes and cell-fate determination in asymmetric divisionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of shape-dependent stochastic asymmetric cell divisionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Integrative approaches toward the development of next-generation therapeutics for myocardial infarction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism underlying metameric morphogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Movement and function of secreted signaling proteins in the extracellular environment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Negative Regulation of Cytokine Signaling in Immunity2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Memory of cell shape biases stochastic fate decision-making despite mitotic rounding2016

Author(s)

Journal Title

Data Source

[Journal Article] Paf1 complex homologes are required for Notch-regulated transcription during somite segmentation2007

Author(s)

Journal Title

Data Source

[Journal Article] Paf1 complex homologes are required for Notch-regulated transcription du ring somite segmentation2007

Author(s)

Journal Title

Data Source

[Journal Article] Paf1 complex homologes are required for Notch-regulated transcription during somite segmentation.2007

Author(s)

Journal Title

Data Source

[Journal Article] Paf1 complexhomologes are required for Notch-regulated transcription during somite segmentation2007

Author(s)

Journal Title

Akanuma Takashi 赤沼啓志

AKANUMA Takashi 赤沼啓志