Ayuzawa Nobuhiro 鮎澤信宏

… Alternative Names

鮎澤信宏アユザワノブヒロ

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Researcher Number	50459517
Other IDs
Affiliation (Current)	2025: 杏林大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 杏林大学, 医学部, 助教 2019 – 2021: 東京大学, 先端科学技術研究センター, 特任助教 2014 – 2019: 東京大学, 先端科学技術研究センター, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Cardiovascular medicine Except Principal Investigator Kidney internal medicine / Medium-sized Section 53:Organ-based internal medicine and related fields / Endocrinology
Keywords	Principal Investigator 高血圧 / ミネラロコルチコイド受容体 / ミネラルコルチコイド受容体 / pendrin / Pendrin / アルドステロン / アンジオテンシンII / 腎臓 / Rac1 / 腎尿細管 … More / 食塩感受性高血圧 / アルカローシス / 尿細管 / 腎 / ミネラロコルチコイド / 食塩感受性 / NCC / トランスジェニックマウス / ノックアウトマウス / 酸化ストレス / 低分子G蛋白質 / 鉱質コルチコイド受容体 / 低分子量G蛋白質 / 心不全 … More Except Principal Investigator 高血圧 / ミネラルコルチコイド / エピジェネティクス / 内科 / 食塩感受性高血圧 / 尿中マーカー / 近位尿細管 / 集合管 / 糖尿病性腎症 / 高血圧学 / コルチゾール / DOHaD / ミネラルコルチコイド受容体 / 加齢 / 糖尿病性腎臓病 / アルドステロン / 腎臓病 / 環境因子 / 糖質コルチコイド / 鉱質コルチコイド / ミネラロコルチコイド受容体 / 酸塩基異常 / ペンドリン / 鉱質コルチコイド受容体 / 遠位尿細管 / 腎障害 Less

腎β間在細胞pendrinの制御機構とその高血圧性病態における意義の解明Principal Investigator
- Principal Investigator
  
  鮎澤信宏
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyorin University
Analysis of the mechanism and role of mineralocorticoid receptor-mediated regulation of pendrinPrincipal Investigator
- Principal Investigator
  
  Ayuzawa Nobuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyorin University
  The University of Tokyo
Integrative elucidation of lifestyle diseases using the epigenomic memory of kidney cells
- Principal Investigator
  
  Fujita Toshiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
Analysis of pendrin regulation using mice with deletion of mineralocorticoid receptor in renal intercalated cellsPrincipal Investigator
- Principal Investigator
  
  Ayuzawa Nobuhiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
Exploration of gluco- and mineralocorticoid-dependent sodium transporter system involved in salt sensitive hypertension
- Principal Investigator
  
  Fujita Toshiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  The University of Tokyo
生活習慣病の高血圧／臓器障害における糖質・鉱質コルチコイドの役割と新規治療探索
- Principal Investigator
  
  Fujita Toshiro
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction
- Principal Investigator
  
  FUJITA Toshiro
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Role of Rac1-mediated activation of mineralocorticoid receptor in heart failurePrincipal Investigator
- Principal Investigator
  
  Ayuzawa Nobuhiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book Other

[Book] 専門医のための腎臓病学 (監修内山聖, 富野康日己, 今井裕一), I 症候編, 11 電解質異常, 高・低K血症，高・低Mg血症2023
- Author(s)
  鮎澤信宏、要伸也
- Total Pages
  680
- Publisher
  医学書院
- ISBN
  9784260051002
- Data Source
  KAKENHI-PROJECT-23K07722
[Book] 医学のあゆみ278巻4号　TOPICS腎臓内科学　ミネラロコルチコイド受容体によるpendrin活性化2021
- Author(s)
  鮎澤信宏
- Total Pages
  70
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20K21596
[Book] 医学の歩み 278巻4号 p295-296: TOPICS 腎臓内科学ミネラロコルチコイド受容体によるpendrin活性化2021
- Author(s)
  鮎澤信宏, 藤田敏郎
- Total Pages
  70
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20K08585
[Journal Article] Rac1 deficiency impairs postnatal development of the renal papilla2022
- Author(s)
  Ayuzawa Nobuhiro、Nishimoto Mitsuhiro、Kawarazaki Wakako、Oba Shigeyoshi、Marumo Takeshi、Aiba Atsu、Fujita Toshiro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20310-20310
- DOI
  10.1038/s41598-022-24462-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08585
[Journal Article] The Mineralocorticoid Receptor in Salt-Sensitive Hypertension and Renal Injury2021
- Author(s)
  Ayuzawa Nobuhiro, Fujita Toshiro
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 32 Issue: 2 Pages: 279-289
- DOI
  10.1681/asn.2020071041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08585, KAKENHI-PROJECT-20K21596, KAKENHI-PROJECT-15H05788
[Journal Article] Activation of Rac1-mineralocorticoid receptor pathway contributes to renal injury in salt-loaded db/db mice.2021
- Author(s)
  Hirohama D, Nishimoto M, Ayuzawa N, Kawarazaki W, Fujii W, Oba S, Shibata S, Marumo T, Fujita T.
- Journal Title
  
  Hypertension
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05788
[Journal Article] Low-dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents2020
- Author(s)
  Wang Conghui、Kawakami-Mori Fumiko、Kang Lei、Ayuzawa Nobuhiro、Ogura Sayoko、Koid Suang Suang、Reheman Latapati、Yeerbolati Alimila、Liu Beibei、Yatomi Yutaka、Chen Xiangmei、Fujita Toshiro、Shimosawa Tatsuo
- Journal Title
  
  Kidney International
  
  Volume: 98 Issue: 5 Pages: 1242-1252
- DOI
  10.1016/j.kint.2020.05.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05788
[Journal Article] Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency2020
- Author(s)
  Kawarazaki Wakako、Mizuno Risuke、Nishimoto Mitsuhiro、Ayuzawa Nobuhiro、Hirohama Daigoro、Ueda Kohei、Kawakami-Mori Fumiko、Oba Shigeyoshi、Marumo Takeshi、Fujita Toshiro
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 130 Pages: 4152-4166
- DOI
  10.1172/jci134431
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08672, KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-18K08028, KAKENHI-PROJECT-19K22984
[Journal Article] Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, and Toshiro Fujita
- Journal Title
  
  Hypertension
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Journal Article] Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury2016
- Author(s)
  Nobuhiro Ayuzawa, Miki Nagase, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Takeshi Marumo, Atsu Aiba, Takayuki Sakurai, Takayuki Shindo, Toshiro Fujita
- Journal Title
  
  Hypertension
  
  Volume: 67 Issue: 1 Pages: 99-106
- DOI
  10.1161/hypertensionaha.115.06054
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860546, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-25461230, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-26670426, KAKENHI-PROJECT-26670427, KAKENHI-PROJECT-26293085
[Journal Article] Rac1-mediated activation of mineralocorticoid receptor in pressure overload-induced cardiac injury2015
- Author(s)
  Ayuzawa N, Nagase M, Ueda K, Nishimoto M, Kawarazaki W, Marumo T, Sakurai T, Shindo T, Fujita T
- Journal Title
  
  Hypertension
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02538
[Presentation] 低分子量GTPase Rac1の腎髄質発生における役割2023
- Author(s)
  鮎澤信宏
- Organizer
  高血圧フォーラム2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K07722
[Presentation] 遠位ネフロン特異的Rac1欠損マウスでは腎髄質の生後の発達が障害される2022
- Author(s)
  鮎澤信宏、西本光宏、河原崎和歌子、大庭成喜、丸茂丈史、饗場篤、藤田敏郎
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08585
[Presentation] 腎臓におけるMRを介した間在細胞pendrinの制御機構とその意義2021
- Author(s)
  鮎澤信宏
- Organizer
  第57回高血圧関連疾患モデル学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08585
[Presentation] Klotho 減少は高カリウム血症の原因となりうる2021
- Author(s)
  河原崎　和歌子，鮎澤　信宏，広浜　大五郎，西本　光宏，大庭　成喜，丸茂　丈史，藤田　敏郎.
- Organizer
  第67回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] 「ミネラロコルチコイド受容体を介した間在細胞pendrinの制御機構」2021
- Author(s)
  鮎澤信宏
- Organizer
  第25回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] 「MRを介した間在細胞 pendrinの制御機構」2021
- Author(s)
  鮎澤信宏, 河原崎和歌子，大庭成喜，藤田敏郎
- Organizer
  第67回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] 加齢に伴う高血圧発症機序の解明～食塩の関与～」2021
- Author(s)
  河原崎和歌子, 鮎澤信宏，大庭成喜，藤田敏郎
- Organizer
  第67回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] ミネラロコルチコイド受容体を介した間在細胞pendrinの制御機構（高峰譲吉研究奨励賞受賞講演）2021
- Author(s)
  鮎澤信宏
- Organizer
  第25回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08585
[Presentation] Rac1－ミネラルコルチコイド受容体系活性化は糖尿病性腎臓病進展に寄与する2021
- Author(s)
  広浜　大五郎，西本　光宏，鮎澤　信宏，河原崎　和歌子，藤井　航，大庭　成喜，柴田　茂，丸茂　丈史，藤田　敏郎
- Organizer
  第67回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] MRを介した間在細胞pendrinの制御機構2021
- Author(s)
  鮎澤信宏
- Organizer
  第64回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08585
[Presentation] 「腎臓におけるMRを介した間在細胞pendrinの制御機構とその意義」2021
- Author(s)
  鮎澤信宏
- Organizer
  第25回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] Pendrin制御とα-ケトグルタル酸2020
- Author(s)
  鮎澤信宏
- Organizer
  第63回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] ポドサイトRac1-ミネラルコルチコイド受容体(MR)系活性化は糖尿病性腎臓病進展に寄与する．2020
- Author(s)
  広浜大五郎, 西本光宏, 鮎澤信宏, 河原崎和歌子, 大庭成喜, 丸茂丈史, 藤田敏郎．
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] アルドステロン過剰時のPendrin制御とα-ケトグルタル酸2020
- Author(s)
  鮎澤信宏、広浜大五郎、西本光宏、河原崎和歌子、丸茂丈史、藤田敏郎
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08585
[Presentation] アルドステロン過剰におけるアルカローシス依存性のPendrin制御機構の解析2020
- Author(s)
  鮎澤信宏
- Organizer
  第15回Vascular Biology Innovationに関する研究助成　第15回研究発表会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 新たな糖尿病性腎臓病モデルの開発とミネラルコルチコイド受容体の関与の解明.2020
- Author(s)
  広浜大五郎, 西本光宏, 鮎澤信宏, 河原崎和歌子, 大庭成喜, 丸茂丈史, 藤田敏郎．
- Organizer
  第56回高血圧関連疾患モデル学会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] 加齢に伴う食塩感受性高血圧発症における腎血管性機序の検討2020
- Author(s)
  河原崎和歌子, 水野理介, 西本光宏, 鮎澤信宏, 広浜大五郎, 大庭成嘉, 丸茂丈史, 藤田敏郎.
- Organizer
  第63回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] 糖尿病性腎症に生じたメタボリックメモリー関連遺伝子のDNAメチル化異常.2020
- Author(s)
  丸茂丈史、星野純一、山内真之、乳原善文、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、藤田敏郎.
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] アルドステロン過剰時のPendrin制御とα-ケトグルタル酸2020
- Author(s)
  鮎澤信宏、広浜大五郎、西本光宏、河原崎和歌子、丸茂丈史、藤田敏郎．
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] アルドステロン過剰におけるアルカローシス依存性のPendrin制御機構の解析．2020
- Author(s)
  鮎澤信宏
- Organizer
  第15回Vascular Biology Innovationに関する研究助成発表会
- Data Source
  KAKENHI-PROJECT-20K21596
[Presentation] Two different mechanism of pendrin regulation by mineralocorticoid receptor in distal nephron2019
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Wakako Kawarazaki, Takeshi Marumo, Toshiro Fujita
- Organizer
  The International Symposium of Aldosterone and Related Substance in Hypertension 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15969
[Presentation] Two distinct regulations of pendrin by mineralocorticoid receptor in distal nephron2019
- Author(s)
  Nobuhiro Ayuzawa
- Organizer
  The 44th International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15969
[Presentation] ミネラロコルチコイド過剰におけるアルカローシス依存性のPendrin制御機構2019
- Author(s)
  鮎澤信宏
- Organizer
  第14回Vascular Biology Innovationに関する研究助成　第14回研究発表会（VBIC）
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] ミネラロコルチコイド過剰による食塩感受性高血圧におけるPendrin活性化機構2019
- Author(s)
  鮎澤信宏
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Two different mechanism of pendrin regulation by mineralocorticoid receptor in distal nephron.2019
- Author(s)
  Nobuhiro Ayuzawa
- Organizer
  International Symposium of Aldosterone and Related Substances in Hypertension 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] ミネラロコルチコイド過剰による食塩感受性高血圧におけるPendrin活性化機構2019
- Author(s)
  鮎澤信宏、広浜大五郎、西本光宏、河原崎和歌子、丸茂丈史、藤田敏郎
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15969
[Presentation] Two distinct regulations of pendrin by mineralocorticoid receptor in distal nephron2019
- Author(s)
  Nobuhiro Ayuzawa
- Organizer
  The 44th International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Two distinct regulations of pendrin by mineralocorticoid receptor in distal nephron2019
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Wakako Kawarazaki, Takeshi Marumo, Toshiro Fujita
- Organizer
  The 44th International Aldosterone Conference,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates RAAS-driven pendrin regulation to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15969
[Presentation] Pendrinの血圧・電解質代謝調節作用に関する役割2018
- Author(s)
  広浜大五郎, 鮎澤信宏, 西本光宏, 河原崎和歌子, 下澤達雄, 丸茂丈史, 柴田茂, 藤田敏郎
- Organizer
  第41回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Pendrinの血圧・水電解質代謝調節作用に関する検討2018
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第22回日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Pendrinの血圧・電解質代謝調節作用に関する役割2018
- Author(s)
  広浜大五郎, 鮎澤信宏, 西本光宏, 河原崎和歌子, 下澤達雄, 丸茂丈史, 柴田茂, 藤田敏郎
- Organizer
  第54回高血圧関連疾患学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates RAAS-driven pendrin regulation to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita.
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 加齢に伴う食塩感受性高血圧発症機序の検討2018
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、丸茂丈史、藤田敏郎
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 加齢に伴う食塩感受性高血圧発症におけるKlotho-Wnt-Rho pathwayの関与2018
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、森典子、大庭成喜、丸茂丈史、藤田敏郎
- Organizer
  第41回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎臓特異的DNAメチル化を尿中マーカーとした糖尿病性腎症の尿細管障害診断法2018
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、佐藤敦久、渥美義仁、星野純一、乳原善文、藤田敏郎
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Seminar, Angiotensin
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860546
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Conference, Angiotensin
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860546
[Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017
- Author(s)
  広浜大五郎、柴田茂、上田浩平、鮎澤信宏、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 食塩感受性高血圧の内分泌学的および腎生理学的検討2017
- Author(s)
  西本光宏、上田浩平、河原崎和歌子、水野理介、森典子、渡邉篤史、広浜大五郎、鮎澤信宏、大庭成喜、丸茂丈史、藤田敏郎
- Organizer
  第90回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017
- Author(s)
  河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017
- Author(s)
  渡邉篤史丸茂丈史河原崎和歌子西本光宏鮎澤信宏広浜大五郎上田浩平熊谷裕生藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 加齢と食塩感受性高血圧～抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する～2017
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  American Society of Nephrology Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017
- Author(s)
  広浜大五郎、柴田茂、上田浩平、鮎澤信宏、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第21回心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017
- Author(s)
  河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  American Society of Nephrology Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
- Organizer
  AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 食塩感受性高血圧の内分泌学的および腎生理学的検討2017
- Author(s)
  西本光宏、上田浩平、河原崎和歌子、水野理介、森典子、渡邉篤史、広浜大五郎、鮎澤信宏、大庭成喜、丸茂丈史、藤田敏郎
- Organizer
  第90回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 腎臓特異的な11beta HSD2活性低下による高血圧発症機序の解析2017
- Author(s)
  上田浩平、西本光宏、広浜大五郎、鮎澤信宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
- Organizer
  AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 腎臓特異的な11beta HSD2活性低下による高血圧発症機序の解析2017
- Author(s)
  上田浩平、西本光宏、広浜大五郎、鮎澤信宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-26860546
[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第21回心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病腎メサンギウム細胞のDNAメチル化異常によるTGFｂ発現増加をRA系阻害薬は抑制する2017
- Author(s)
  大庭成喜、広浜大五郎、鮎澤信宏、西本光宏、河原崎和歌子、上田浩平、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017
- Author(s)
  渡邉篤史丸茂丈史河原崎和歌子西本光宏鮎澤信宏広浜大五郎上田浩平熊谷裕生藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 加齢と食塩感受性高血圧～抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する～2017
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016
- Author(s)
  広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016
- Author(s)
  鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016
- Author(s)
  鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] The mechanism of blood pressure elevation in distal nephron-specific Hsd11b2 knockout mice2016
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Nobuhiro Ayuzawa, Daigoro Hirohama, Atsushi Watanabe, Takeshi Marumo, Toshiro Fujita
- Organizer
  The 41st International Aldosterone Conference Aldosterone and Mineralocorticoids
- Place of Presentation
  Boston, USA
- Year and Date
  2016-03-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016
- Author(s)
  河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016
- Author(s)
  河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016
- Author(s)
  広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] 糖尿病性腎症で核内受容体PXRはエピジェネティクス異常をきたし線維化因子RGC32を増加させる2016
- Author(s)
  渡邉篤史, 丸茂丈史, 河原崎和歌子, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 熊谷裕生, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K15494
[Presentation] Activation of Rac1-MR pathway in heart failure2015
- Author(s)
  Nobuhiro Ayuzawa
- Organizer
  The 8th International Aldosterone Forum in Japan
- Place of Presentation
  THE GRAND HALL（品川）、東京都
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-26860546
[Presentation] 遠位ネフロン特異的Rac1欠損マウスを用いたRac1-ミネラロコルチコイド受容体（MR）経路の解析2015
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Eplerenoneは塩分過剰摂取によるRA系阻害抵抗性腎障害を抑制する−EVALUATE試験サブ解析−2015
- Author(s)
  西本光宏、大津洋、丸茂丈史、河原崎和歌子、鮎澤信宏、上田浩平、広浜大五郎、渡邉篤史、藤田敏郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Activation of Rac1-MR pathway in heart failure2015
- Author(s)
  Nobuhiro Ayuzawa
- Organizer
  8th International Aldosterone Forum in Japan
- Place of Presentation
  Tokyo (Japan)
- Year and Date
  2015-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860546
[Presentation] Epigenetic abnormalities underlie increased expression of nuclear receptor PXR in diabetic kidney disease2015
- Author(s)
  Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Kohei Ueda, Hiroo Kumagai, Toshiro Fujita
- Organizer
  Kidney Week 2015 ASN Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
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1. Fujita Toshiro (10114125)

# of Collaborated Projects: 4 results

# of Collaborated Products: 59 results
2. 丸茂丈史 (70265817)

# of Collaborated Projects: 4 results

# of Collaborated Products: 56 results
3. 広浜大五郎 (20749353)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
4. 河原崎和歌子 (50424594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
5. 柴田茂 (60508068)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. 大庭成喜 (80361492)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. 下澤達雄 (90231365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
8. 西本光宏 (90646572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 32 results
9. 上田浩平 (80735697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
10. 森典子 (80431857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Ayuzawa Nobuhiro 鮎澤 信宏

鮎澤 信宏 アユザワ ノブヒロ

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Research Products

Co-Researchers

腎β間在細胞pendrinの制御機構とその高血圧性病態における意義の解明Principal Investigator

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Analysis of the mechanism and role of mineralocorticoid receptor-mediated regulation of pendrinPrincipal Investigator

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Integrative elucidation of lifestyle diseases using the epigenomic memory of kidney cells

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Analysis of pendrin regulation using mice with deletion of mineralocorticoid receptor in renal intercalated cellsPrincipal Investigator

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Exploration of gluco- and mineralocorticoid-dependent sodium transporter system involved in salt sensitive hypertension

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生活習慣病の高血圧／臓器障害における糖質・鉱質コルチコイドの役割と新規治療探索

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Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction

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Role of Rac1-mediated activation of mineralocorticoid receptor in heart failurePrincipal Investigator

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[Book] 専門医のための腎臓病学 (監修 内山聖, 富野 康日己, 今井 裕一), I 症候編, 11 電解質異常, 高・低K血症，高・低Mg血症2023

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[Book] 医学のあゆみ278巻4号 TOPICS腎臓内科学 ミネラロコルチコイド受容体によるpendrin活性化2021

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[Book] 医学の歩み 278巻4号 p295-296: TOPICS 腎臓内科学 ミネラロコルチコイド受容体によるpendrin活性化2021

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[Journal Article] Rac1 deficiency impairs postnatal development of the renal papilla2022

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[Journal Article] The Mineralocorticoid Receptor in Salt-Sensitive Hypertension and Renal Injury2021

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[Journal Article] Activation of Rac1-mineralocorticoid receptor pathway contributes to renal injury in salt-loaded db/db mice.2021

Ayuzawa Nobuhiro 鮎澤信宏

鮎澤信宏アユザワノブヒロ

[Book] 専門医のための腎臓病学 (監修内山聖, 富野康日己, 今井裕一), I 症候編, 11 電解質異常, 高・低K血症，高・低Mg血症2023

[Book] 医学のあゆみ278巻4号　TOPICS腎臓内科学　ミネラロコルチコイド受容体によるpendrin活性化2021

[Book] 医学の歩み 278巻4号 p295-296: TOPICS 腎臓内科学ミネラロコルチコイド受容体によるpendrin活性化2021