SHIBATA Aya 柴田綾

… Alternative Names

柴田綾シバタアヤ

Less

Researcher Number	50462693
Other IDs
Affiliation (Current)	2025: 岐阜大学, 工学部, 助教
Affiliation (based on the past Project Information) *help	2015 – 2023: 岐阜大学, 工学部, 助教 2010 – 2011: 独立行政法人理化学研究所, 伊藤ナノ医工学研究室, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Analytical chemistry / Basic Section 34020:Analytical chemistry-related / Drug development chemistry Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator 遺伝子検出 / 芳香族求核置換反応 / バイオ分析 / クリック反応 / アリールスルホニル基 / ^<19> F-NMRプローブ / 化学発光プローブ / 蛍光プローブ / アリールスルフォニル基 / グルタチオン-S-トランスフェラーゼ … More Except Principal Investigator … More 生理活性 / 有機化学 / 薬学 / 効率的合成 / ポスト修飾 / CuAAC / 簡便合成 / 分解酵素耐性 / 環境応答 / 機能性短鎖RNA / 核酸医薬 Less

Development of the chemical reaction probes for intracellular miRNA detectionPrincipal Investigator
- Principal Investigator
  
  Shibata Aya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  Gifu University
Development of the nucleic acid sensing probe based on molecule transfer.Principal Investigator
- Principal Investigator
  
  Shibata Aya
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Analytical chemistry
- Research Institution
  Gifu University
Development of sophisticated small RNAs utilizing the properties of functional groups
- Principal Investigator
  
  KITAMURA Yoshiaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
Development of the molecular transfer based oligonucleotide sensing probePrincipal Investigator
- Principal Investigator
  
  SHIBATA Aya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Analytical chemistry
- Research Institution
  Gifu University
Development of GST detection probe, and intracellular drug screeningPrincipal Investigator
- Principal Investigator
  
  SHIBATA Aya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2018 2017 2016 2012 2011 2010

All Journal Article Presentation Patent

[Journal Article] Nucleobase azide-ethynylribose click chemistry contributes to stabilizing oligonucleotide duplexes and stem-loop structures2017
- Author(s)
  Yoshiaki Kitamura, Ryo Asakura, Koki Terazawa, Aya Shibata, Masato Ikeda, Yukio Kitade
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 12 Pages: 2655-2658
- DOI
  10.1016/j.bmcl.2017.04.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18911
[Journal Article] Introduction of 2-O-benzyl abasic nucleosides to the 3'-overhang regions of siRNAs greatly improves nuclease resistance2017
- Author(s)
  Yuki Nagaya, Yoshiaki Kitamura, Aya Shibata, Masato Ikeda, Yukihiro Akao, Yukio Kitade
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 24 Pages: 5454-5456
- DOI
  10.1016/j.bmcl.2017.10.070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18911
[Journal Article] Universal Caging Group for In Cell Detection of Glutathione Transferase Applied to 19F NMR and Bioluminogenic Probes.2012
- Author(s)
  Ito M., Shibata A., Zhang J., Hiroshima M., Sako Y., Nakano Y., Kojima-Aikawa K., Mannervik B., Shuto S., Ito Y., Morgenstern R. and Abe H.
- Journal Title
  
  ChemBioChem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790124
[Journal Article] Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy2011
- Author(s)
  Zhang J, Shibata A, Ito M, Shuto S, Ito Y, Mannervik B, Abe H, Morgenstern R
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 133 Issue: 35 Pages: 14109-14119
- DOI
  10.1021/ja205500y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790124
[Journal Article] Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance.2011
- Author(s)
  Johansson K., Ito M., Schophuizen C. M., Mathew Thengumtharayil S., Heuser V. D., Zhang J., Shimoji M., Vahter M., Ang W. H., Dyson P. J., Shibata A., Shuto S., Ito Y., Abe H. and Morgenstern R.
- Journal Title
  
  Mol. Pharmaceutics
  
  Volume: 8 Pages: 1698-1708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790124
[Journal Article] Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy.2011
- Author(s)
  Zhang J., Shibata A., Ito M., Shuto S., Ito Y., Mannervik B., Abe H. and Morgenstern R.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 133 Pages: 14109-14119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790124
[Journal Article] Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance2011
- Author(s)
  Johansson K, Ito M, Schophuizen CM, Mathew Thengumtharayil S, Heuser VD, Zhang J, Shimoji M, Vahter M, Ang WH, Dyson PJ, Shibata A, Shuto S, Ito Y, Abe H, Morgenstern R
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 8 Issue: 5 Pages: 1698-1708
- DOI
  10.1021/mp2000692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790124
[Patent] グルタチオン-S-トランスフェラーゼを用いた脱保護法、及びその利用2010
- Inventor(s)
  阿部洋、柴田綾、伊藤嘉浩、伊藤美香
- Industrial Property Rights Holder
  理化学研究所
- Industrial Property Number
  2010-214260
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] 塩基部欠損ヌクレオシド類を 3’末端に有する siRNA の合成と性質評価2018
- Author(s)
  長屋優貴, 喜多村徳昭, 柴田綾, 池田将, 赤尾幸博, 北出幸夫
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K18911
[Presentation] Nucleobase azide-ethynylribose click chemistry: stabilizing oligonucleotide duplexes and stem-loop structures2017
- Author(s)
  Yoshiaki Kitamura, Ryo Asakura, Koki Terazawa, Aya Shibata, Masato Ikeda, Yukio Kitade
- Organizer
  第44回国際核酸化学シンポジウム（ISNAC2017）・日本核酸化学会第1回年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18911
[Presentation] リボース誘導体を母核とする新規traceless型リンカーの開発2017
- Author(s)
  寺澤康輝, 喜多村徳昭, 長屋優貴, 柴田綾, 池田将, 北出幸夫
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2017
- Data Source
  KAKENHI-PROJECT-16K18911
[Presentation] Nucleobase azide-ethynylribose click chemistry contributes to stabilizing oligonucleotide duplexes and stem-loop　structures2017
- Author(s)
  Yoshiaki Kitamura, Ryo Asakura, Koki Terazawa, Aya Shibata, Masato Ikeda, Yukio Kitade
- Organizer
  第26回国際複素環化学会議（26th ISHC Congress）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18911
[Presentation] Synthesis of chemically modified siRNAs bearing high affinity molecules for human Argonaute 2 PAZ domain and their biological properties2016
- Author(s)
  Yoshiaki Kitamura, Yuki Nagaya, Kazuhito Kondo, Ryo Asakura, Qin Ren, Mahmoud Kandeel, Aya Shibata, Masato Ikeda, Yukio Kitade
- Organizer
  第43回国際核酸化学シンポジウム（ISNAC2016）
- Place of Presentation
  熊本大学（熊本）
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18911
[Presentation] トリアゾール環形成による二本鎖核酸の安定化2016
- Author(s)
  朝倉領、喜多村徳昭、柴田綾、池田将、北出幸夫
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
- Place of Presentation
  長良川国際会議場（岐阜）
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-16K18911
[Presentation] グルタチオン-S-トランスフェラーゼ検出プローブの合成と性質2011
- Author(s)
  柴田綾、Zhang Jie、伊藤美香、周東智、Mannervik Beng、阿部洋、Morgenstern Ralf、伊藤嘉浩
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  茨城県つくば市
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] 生物学研究のための光プローブ2011
- Author(s)
  柴田綾
- Organizer
  第6回理研「バイオものづくり」シンポジウム
- Place of Presentation
  埼玉県和光市(招待講演)
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] 生物学研究のための光プローブ2011
- Author(s)
  柴田綾
- Organizer
  第6回理研「バイオものづくり」シンポジウム
- Place of Presentation
  埼玉県和光市
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] 新規蛍光プローブの合成とグルタチオントランスフェラーゼに対する基質特異性の解析2011
- Author(s)
  伊藤美香,柴田綾,阿部洋, Zhang Jie, Morgenstern Ralf,周東智,伊藤嘉浩
- Organizer
  日本薬学会第131年回
- Place of Presentation
  静岡県静岡市
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] 細胞内グルタチオン-S-トランスフェラーゼ活性検出のためのプローブ開発2010
- Author(s)
  柴田綾、阿部洋、伊藤美香、Morgenstern Ralf、周東智、伊藤嘉浩
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪府大阪市
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] グルタチオントランスフェラーゼの基質となる発光プローブの開発2010
- Author(s)
  伊藤美香,柴田綾,阿部洋, Morgenstern Ralf,周東智,伊藤嘉浩
- Organizer
  第29回メデジシナルケミストリーシンポジウム
- Place of Presentation
  京都府京都市
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] 細胞内グルタチオン-S-トランスフェラーゼ活性検出のためのプローブ開発2010
- Author(s)
  柴田綾
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪市
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22790124
[Presentation] グルタチオンS-トランスフェラーゼの基質となる発光プローブの開発2010
- Author(s)
  伊藤美香、柴田綾、阿部洋、Morgenstern Ralf、周東智、伊藤嘉浩
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪府大阪市
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22790124

1. KITAMURA Yoshiaki (10503659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. KITADE YUKIO (20137061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. IKEDA MASATO (20432867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

SHIBATA Aya 柴田 綾

柴田 綾 シバタ アヤ

Research Projects

Research Products

Co-Researchers

Development of the chemical reaction probes for intracellular miRNA detectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the nucleic acid sensing probe based on molecule transfer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of sophisticated small RNAs utilizing the properties of functional groups

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the molecular transfer based oligonucleotide sensing probePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of GST detection probe, and intracellular drug screeningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nucleobase azide-ethynylribose click chemistry contributes to stabilizing oligonucleotide duplexes and stem-loop structures2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Introduction of 2-O-benzyl abasic nucleosides to the 3'-overhang regions of siRNAs greatly improves nuclease resistance2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Universal Caging Group for In Cell Detection of Glutathione Transferase Applied to 19F NMR and Bioluminogenic Probes.2012

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance.2011

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy.2011

Author(s)

Journal Title

Data Source

[Journal Article] Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance2011

Author(s)

Journal Title

DOI

Data Source

[Patent] グルタチオン-S-トランスフェラーゼを用いた脱保護法、及びその利用2010

Inventor(s)

Industrial Property Rights Holder

Industrial Property Number

Filing Date

Data Source

[Presentation] 塩基部欠損ヌクレオシド類を 3’末端に有する siRNA の合成と性質評価2018

Author(s)

Organizer

Data Source

[Presentation] Nucleobase azide-ethynylribose click chemistry: stabilizing oligonucleotide duplexes and stem-loop structures2017

Author(s)

Organizer

SHIBATA Aya 柴田綾

柴田綾シバタアヤ

[Presentation] Nucleobase azide-ethynylribose click chemistry contributes to stabilizing oligonucleotide duplexes and stem-loop　structures2017