Sasaki Tsutomu 佐々木努

… Alternative Names

SASAKI Tsutomu 佐々木努

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Researcher Number	50466687
Other IDs	https://orcid.org/0000-0001-8041-1915
Affiliation (Current)	2022: 京都大学, 農学研究科, 教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 京都大学, 農学研究科, 教授 2017 – 2018: 群馬大学, 生体調節研究所, 准教授 2012 – 2015: 群馬大学, 生体調節研究所, 准教授 2011: 群馬大学, 生体調節研究所, 助教 2008 – 2009: Gunma University, 生体調節研究所, 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Metabolomics / Environmental physiology (including Physical medicine and Nutritional physiology) / Biological Sciences / Environmental physiology(including physical medicine and nutritional physiology) / Complex systems / Eating habits / Medium-sized Section 38:Agricultural chemistry and related fields
Keywords	Principal Investigator 視床下部 / SIRT1 / Sirt1 / オキシトシン / 食欲 / 生理学 / FGF21 / 嗜好性 / 脳・神経 / 摂食調節 … More / サーチュイン / 生体恒常性 / 臓器連関 / 飲酒欲求 / 糖尿病 / 嘉現制御 / エネルギー消費 / 交感神経 / 褐色脂肪 / sirtuin / 摂食 / ユビキチン化 / E3リガーゼ / 翻訳後修飾 / Foxo1 / インスリンシグナル / エネルギー代謝 / インスリン抵抗性 / FoxO1 / レプチン / POMC / ストレス反応 / ストレス抵抗性 / 意欲 / 社会敗北ストレス / 拘束ストレス / コルチコステロン / ストレス / 栄養素嗜好性 / 単純糖質 / 中鎖脂肪酸 / 食行動 / 脂肪酸 / 食品 / 神経科学 / 糖 / 飲酒 / アルコール / 栄養 / 代謝 / 代謝性シグナル / 栄養代謝 / マクロ栄養素 / 脳 / アルコール嗜好性 / 代謝シグナル / 神経回路 Less

Elucidating how homeostasis is maintained through nutrition-based appetitePrincipal Investigator
- Principal Investigator
  
  佐々木努
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Kyoto University
Elucidating neural circuit that regulates alcohol intake through metabolic signalingPrincipal Investigator
- Principal Investigator
  
  佐々木努
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kyoto University
Elucidating how the longevity gene SIRT1 regulate alcohol preference.Principal Investigator
- Principal Investigator
  
  Sasaki Tsutomu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kyoto University
  Gunma University
Elucidating the role of brain SIRT1, an integrator of external and internal environment, in regulating will and motivation.Principal Investigator
- Principal Investigator
  
  佐々木努
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Gunma University
Elucidating the neuronal regulation of food preferece; focusing on the longevity gene SIRT1Principal Investigator
- Principal Investigator
  
  Sasaki Tsutomu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Kyoto University
  Gunma University
Hypothalamic Sirt1 and FoxO1 in energy balance regulationPrincipal Investigator
- Principal Investigator
  
  Sasaki Tsutomu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Gunma University
代謝シグナルによる視床下部ＮＡＤ依存性脱アセチル化酵素ＳＩＲＴ１の制御機構の解明Principal Investigator
- Principal Investigator
  
  佐々木努
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Elucidation of the role of hypothalamic Sirt1 in energy balance regulation.Principal Investigator
- Principal Investigator
  
  SASAKI Tsutomu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Gunma University
Investigation into the role of hypothalamic SIRT1 in regulating energy metabolism.Principal Investigator
- Principal Investigator
  
  SASAKI Tsutomu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University

All 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

[Book] もっとよくわかる！食と栄養のサイエンス2021
- Author(s)
  佐々木　努（編）
- Total Pages
  213
- Publisher
  羊土社
- ISBN
  9784758122092
- Data Source
  KAKENHI-PROJECT-20H00412
[Journal Article] Neuronal sirtl regulates macronutrient-based diet selection through fgf21 and oxytocin signalling in mice.2018
- Author(s)
  Matsui S, Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O. Suga T. Kobayashi M. Yamanaka A, Harada A, Nakagawa T. Onaka T, Kitamura T.
- Journal Title
  
  Nat Commun
  
  Volume: 9 Issue: 1 Pages: 1-17
- DOI
  10.1038/s41467-018-07033-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08527, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-18K17921, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-17H05563, KAKENHI-PUBLICLY-17H06061, KAKENHI-PLANNED-17H06422, KAKENHI-PUBLICLY-18H05124, KAKENHI-PROJECT-17H01971, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-18H02594, KAKENHI-PROJECT-17K16139, KAKENHI-PROJECT-16H06276
[Journal Article] Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice.2014
- Author(s)
  Susanti VY, Sasaki T, Yokota-Hashimoto H, Matsui S, Lee YS, Kikuchi O, Shimpuku M, Kim HY, Kobayashi M, Kitamura T.
- Journal Title
  
  Obesity
  
  Volume: 22 Pages: 2115-9
- DOI
  10.1002/oby.20838
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460310
[Journal Article] Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via AgRP2010
- Author(s)
  佐々木努
- Journal Title
  
  Endocrinology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790637
[Journal Article] Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via AgRP2010
- Author(s)
  佐々木努, 金惠珍, 小林雅樹, 北村ゆかり, 橋本(横田)博美, 志内哲也, 箕越靖彦, 北村忠弘
- Journal Title
  
  Endocrinology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790637
[Patent] 線維芽細胞増殖因子21誘導剤、及びアルコール嗜好性又は単純糖質嗜好性を抑制するための組成物2021
- Inventor(s)
  佐々木努、松居翔
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K21756
[Presentation] 食行動を調節する栄養シグナルの解明2021
- Author(s)
  佐々木努
- Organizer
  第41回日本肥満学会・第38回日本肥満症治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00412
[Presentation] 代謝性シグナルによる食欲調節2020
- Author(s)
  佐々木努
- Organizer
  第6回日本農芸化学会関西支部　産官学連携シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H00412
[Presentation] 低タンパク質食摂取に伴う血中FGF21濃度変動によるタンパク質嗜好性の調節2020
- Author(s)
  河内花菜子、松居翔、都築巧、佐々木努
- Organizer
  第59回日本栄養・食糧学会近畿支部大会
- Data Source
  KAKENHI-PROJECT-20H00412
[Presentation] グルカゴンがタンパク質嗜好性に及ぼす影響2020
- Author(s)
  松居翔、中川祐子、藤谷与士夫、北村忠弘、佐々木努
- Organizer
  第14回日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-20H00412
[Presentation] Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice2019
- Author(s)
  Tsutomu Sasaki, Sho Matsui, Daisuke Kohno, Tadahiro Kitamura
- Organizer
  Keystone symposium on Functional Neurocircuitry of Feeding and Feeding Disorders
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] Oxytocin neuron in the paraventricular nucleus of the hypothalamus regulates FGF21- and SIRT1-based simple sugar preference in mice2019
- Author(s)
  Sho Matsui, Tsutomu Sasaki, Daisuke Kohno, Tadahiro Kitamura
- Organizer
  Keystone symposium on Functional Neurocircuitry of Feeding and Feeding Disorders
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] 視床下部室傍核オキシトシンニューロンのSIRT1がショ糖嗜好性を制御する2018
- Author(s)
  松居翔、佐々木努、河野大輔、橋本博美、小林雅樹、北村忠弘
- Organizer
  第39回日本肥満学会
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] 糖を食べたいと思うメカニズム2018
- Author(s)
  佐々木努
- Organizer
  第40回日本臨床栄養学会・第39回日本臨床栄養協会大連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] Neuronal Sirt1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice.2018
- Author(s)
  Sasaki T, Matsui S, Kitamura T
- Organizer
  26th Annual meeting of the Society for the Study of Ingestive Behavior
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] SIRT1はショ糖摂食選択行動を制御する2018
- Author(s)
  松居翔、佐々木努、河野大輔、橋本博美、小林雅樹、北村忠弘
- Organizer
  第72回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] SIRT1はFGF21-NRF2-oxytocinシグナルを介してショ糖嗜好性を制御する2018
- Author(s)
  松居翔、佐々木努、河野大輔、橋本博美、小林雅樹、北村忠弘
- Organizer
  第91回日本内分泌学会
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] Brain SIRT1 regulates macronutrient-based diet selection behavior through FGF21, NRF2, and oxytocin.2017
- Author(s)
  Sasaki T, Matsui S, Kohno D, Kitamura T
- Organizer
  Consortium of Biological Sciences (2017)
- Invited
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] FGF21によるオキシトシン発現制御機構の解析2017
- Author(s)
  松居翔、佐々木努、橋本博美、河野大輔、小林雅樹、北村忠弘
- Organizer
  第90回日本内分泌学会 (2017)
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] Sirt1 regulates simple sugar selection through FGF21 and oxytocin.2017
- Author(s)
  Matsui S, Sasaki T, Kohno D, Yokota-Hashimoto H, Kobayashi M, Kitamura T
- Organizer
  The 41th Annual meeting of the Japan Neuroscience Society (2017)
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] SIRT1はFGF21-NRF2-oxytocinシグナルを介してショ糖嗜好性を制御する2017
- Author(s)
  松居翔、佐々木努、河野大輔、橋本博美、小林雅樹、北村忠弘
- Organizer
  第38回日本肥満学会 (2017)
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] 脳SIRT1による栄養素嗜好性の制御メカニズム2017
- Author(s)
  佐々木努、松居翔、北村忠弘
- Organizer
  第38回日本肥満学会 (2017)
- Invited
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] Sirt1 regulates simple sugar selection through FGF21 and oxytocin.2017
- Author(s)
  Matsui S, Sasaki T, Kohno D, Yokota-Hashimoto H, Kobayashi M, Kitamura T
- Organizer
  Keystone Symposia: Neuronal Control of Appetite, Metabolism and Weight (2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] Sirt1 suppresses simple sugar preference by regulating oxytocin through NRF2.2017
- Author(s)
  Sasaki T, Matsui S, Kohno D, Yokota-Hashimoto H, Kobayashi M, Kitamura T
- Organizer
  Keystone Symposia: Aging and Mechanisms of Aging-Related Disease (2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01971
[Presentation] 中枢神経系のSIRT1による体重調節2016
- Author(s)
  佐々木努
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-25460310
[Presentation] POMCニューロン特異的核内滞留型・Sirt1ダブルノックインマウスの解析2014
- Author(s)
  佐々木努、スサンティヴィナヤンティ、橋本博美、小林雅樹、北村忠弘
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-25460310
[Presentation] POMC neuron-specific constitutively nuclear FoxO1 and Sirt1 double knock-in mice is rescued from obesity induced by FoxO1.2014
- Author(s)
  Sasaki T, Susanti VY, Kitamura T
- Organizer
  Keystone Symposium “Obesity: A Multisystems Perspective”
- Place of Presentation
  バンクーバー（カナダ）
- Data Source
  KAKENHI-PROJECT-25460310
[Presentation] Sirt1 overexpression in POMC neurons rescues the obese phenotype induced by constitutively-nuclear FoxO1 in male mice.2014
- Author(s)
  Sasaki T, Susanti VY, Yokota-Hashimoto H, Sho Matusi, Kikuchi O, Kobayashi M, Kitamura T
- Organizer
  37th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-25460310
[Presentation] Hypothalamic Sirt1 and energy balance regulation.2014
- Author(s)
  Sasaki T, Kitamura T
- Organizer
  The 91st Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  鹿児島大学郡元キャンパス
- Data Source
  KAKENHI-PROJECT-25460310
[Presentation] Search for the Sirt1 Ubiquitin E3 ligase and their inhibitors2013
- Author(s)
  Sasaki T, and Kitamura T
- Organizer
  International Symposium on Transcription and Metabolism
- Place of Presentation
  Awaji Yumebutai International Conference Center Awaji City, Hyogo, Japan
- Data Source
  KAKENHI-PUBLICLY-24116505
[Presentation] Hypothalamic Sirt1 achieves negative energy balance by stimulating energy expenditure in POMC neurons and by suppressing food intake in AgRP neurons2013
- Author(s)
  Sasaki T, Kitamura T
- Organizer
  Keystone Symposium "Neuronal Control of Appetite, Metabolism and Weight"
- Place of Presentation
  Banff, Alberta(カナダ)
- Year and Date
  2013-03-20
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Roles for hypothalamic FoxO1 and Sirt1 in regulating energy metabolism2013
- Author(s)
  Kitamura T, and Sasaki T
- Organizer
  36th Annual Meeting of the Molecular Biology Society of Japan.
- Place of Presentation
  神戸ポートアイランド
- Invited
- Data Source
  KAKENHI-PROJECT-25460310
[Presentation] 視床下部弓状核のSirt1はエネルギーバランスを負に制御する2013
- Author(s)
  佐々木努、新福摩弓、菊池司、ビナヤンティスサンティ、橋本博美、小林雅樹、北村忠弘
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Hypothalamic Sirt1 overexpression leads to a negative energy balance2013
- Author(s)
  Sasaki T, Shimpuku M, Kikuchi O, Susanti VY, Yokota-Hashimoto H, Kobayashi M, Kitamura T
- Organizer
  The 90th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  東京
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Analyses of POMC neuron-specific constitutively nuclear FoxO1 and Sirt1 double knock-in mice.2013
- Author(s)
  Susanti VY, Sasaki T, Yokota-Hashimoto H, Kobayashi M, Kitamura T
- Organizer
  Japan Society for the Study of Obesity 34rd Annual meeting
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25460310
[Presentation] Induction of Sirt1 expression in the murine hypothalamic AgRP and Pomc neurons leads to lean phenotype due to decreased food intake and increased energy expenditure2012
- Author(s)
  Sasaki T, Shimpuku M, Kikuchi O, Yokota-Hashimoto H, Kobayashi M, Kitamura T
- Organizer
  The 89th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  松本市(長野県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] POMC・AgRPニューロンでのSirt1過剰発現マウスの摂食・エネルギー消費調節機構2012
- Author(s)
  佐々木努、新福摩弓、菊池司、橋本博美、小林雅樹、北村忠弘
- Organizer
  第55回日本糖尿病学会
- Place of Presentation
  横浜
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] POMC・AgRPニューロンでのSirt1過剰発現マウスの摂食・エネルギー消費調節機構2012
- Author(s)
  佐々木努、新福摩弓、菊池司、橋本博美、小林雅樹、北村忠弘
- Organizer
  第33回日本肥満学会
- Place of Presentation
  京都
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Induction of Sirt1 expression in the murine hypothalamic AgRP and Pomc neurons leads to lean phenotype due to decreased food intake and increased energy expenditure2012
- Author(s)
  Sasaki T, Kitazumi T, Amano K, Kikuchi O, Shimpuku M, Yokota-Hashimoto H, Kobayashi M, Kitamura T
- Organizer
  Keystone Symposium "Sirtuins in Metabolism, Aging and Disease"
- Place of Presentation
  Tahoe City, California(米国)
- Year and Date
  2012-02-14
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] POMC・AgRPニューロンでのSirt1過剰発現マウスの摂食・エネルギー消費調節機構2012
- Author(s)
  佐々木努、新福摩弓、菊池司、橋本博美、小林雅樹、北村忠弘
- Organizer
  第85回日本内分泌学会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] 視床下部Sirt1による抗肥満効果の分子メカニズム2012
- Author(s)
  佐々木努、新福摩弓、菊池司、天野剛介、北住知也、橋本博美、小林雅樹、北村忠弘
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Hypothalamic Sirt1 achieves negative energy balance by stimulating energy expenditure in POMC neurons and by suppressing food intake in AgRP neurons2012
- Author(s)
  Tsutomu Sasaki, Mayumi Shimpuku, Osamu Kikuchi, Vina Yanti Susanti, Hiromi Yokota-Hashimoto, Masaki Kobayashi, Tadahiro Kitamura
- Organizer
  Keystone Symposia on Aging and Diseases of Aging
- Place of Presentation
  東京
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Rosa26-Sirt1ノックインマウスを用いた視床下部Sirt1とエネルギーバランスの解析2011
- Author(s)
  佐々木努、天野剛介、北住知也、菊池司、小林雅樹、北村忠弘
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Pomc-Cre; Sirt1 conditional Knock-In Mice Present Lean Phenotype Due to Increased Energy Expenditure2011
- Author(s)
  Tsutomu Sasaki, Kosuke Amano, Tomoya Kitazumi, Osamu Kikuchi, Masaki Kobayashi, Tadahiro Kitamura
- Organizer
  American Diabetes Association 71st Scientific Sessions
- Place of Presentation
  San Diego, California(米国)
- Year and Date
  2011-06-26
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Induction of Sirt1 expression in the murine hypothalamic AgRP and Pomc neurons leads to lean phenotype due to decreased food intake and increased energy expenditure2011
- Author(s)
  Tsutomu Sasaki, Tomoya Kitazumi, Kosuke Amano, Osamu Kikuchi, Hiromi Yokota-Hashimoto, Masaki Kobayashi, Tadahiro Kitamura
- Organizer
  The 34th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] AgRP・PomcニューロンでのSirt1過剰発現マウスでの摂食・エネルギー消費調節機構2011
- Author(s)
  佐々木努、北住知也、天野剛介、菊池司、橋本博美、小林雅樹、北村忠弘
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路島(兵庫)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] POMC陽性神経細胞のSirt1はエネルギー消費を制御する2011
- Author(s)
  佐々木努、天野剛介、北住知也、菊池司、小林雅樹、北村忠弘
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Conditional Knock-in of SIRT1 in AGRP or POMC Neurons Lead to Lean Phenotype due to Decreased Food Intake and Increased Energy Expenditure2011
- Author(s)
  Tsutomu Sasaki, Tadahiro Kitamura
- Organizer
  American Diabetes Association Research Symposium "Diabetes and the Brain"
- Place of Presentation
  Alexandria, Virginia(米国)
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via AgRP2010
- Author(s)
  佐々木努
- Organizer
  第14回国際内分泌学会
- Place of Presentation
  京都国際会館
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20790637
[Presentation] Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via AgRP2010
- Author(s)
  佐々木努
- Organizer
  第14回国際内分泌学会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20790637
[Presentation] Sirt1の視床下部における摂食行動・エネルギー代謝制御機構の解明2009
- Author(s)
  佐々木努
- Organizer
  第82回日本内分泌学会
- Place of Presentation
  前橋商工会議所
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-20790637
[Presentation] Sirt1の視床下部における摂食行動・エネルギー代謝制御機構の解明2009
- Author(s)
  佐々木努
- Organizer
  第30回日本肥満学会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20790637
[Presentation] Sirt1の視床下部における摂食行動・エネルギー代謝制御機構の解明2009
- Author(s)
  佐々木努
- Organizer
  第82回日本内分泌学会
- Place of Presentation
  前橋商工会議所(群馬県)
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-20790637
[Presentation] Sirt1の視床下部における摂食行動・エネルギー代謝制御機構の解明2009
- Author(s)
  佐々木努
- Organizer
  第30回日本肥満学会
- Place of Presentation
  アクトシティ浜松(静岡県)
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20790637
[Presentation] POMC・AgRP ニューロンでのSirt1 過剰発現マウスの摂食・エネルギー消費調節機構
- Author(s)
  佐々木努
- Organizer
  第５５回日本糖尿病学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Hypothalamic Sirt1 overexpression leads to a negative energy balance
- Author(s)
  佐々木努
- Organizer
  第９０回日本生理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] POMC・AgRPニューロンでのSirt1過剰発現マウスの摂食・エネルギー消費調節機構
- Author(s)
  佐々木努
- Organizer
  第８５回日本内分泌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Conditional Knock-in of SIRT1 in AGRP or POMC
- Author(s)
  佐々木努、新福摩弓、菊池司、橋本博美、小林雅樹、北村忠弘
- Organizer
  第８９回日本生理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Hypothalamic Sirt1 achieves negative energy balance by stimulating energy expenditure in POMC neurons and by suppressing food intake in AgRP neurons.
- Author(s)
  佐々木努
- Organizer
  Keystone Symposium “Neuronal Control of Appetite, Metabolism and Weight”
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Conditional Knock-in of SIRT1 in AGRP or POMC
- Author(s)
  佐々木努、北住知也、天野剛介、菊池司、新福摩弓、橋本博美、小林雅樹、北村忠弘
- Organizer
  キーストンシンポジウム
- Place of Presentation
  Tahoe City, California, USA
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] POMC陽性神経細胞のSirt1はエネルギー消費を制御する
- Author(s)
  佐々木　努、天野　剛介、北住　知也、菊池　司、小林　雅樹、北村　忠弘
- Organizer
  第５４回日本糖尿病学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] 視床下部弓状核のSirt1はエネルギーバランスを負に制御する
- Author(s)
  佐々木努
- Organizer
  第８６回日本内分泌学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] 視床下部Sirt1による抗肥満効果の分子メカニズム
- Author(s)
  佐々木努
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] POMC・AgRPニューロンでのSirt1過剰発現マウスの摂食・エネルギー消費調節機構
- Author(s)
  佐々木努
- Organizer
  第３３回日本肥満学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] AgRP・PomcニューロンでのSirt1過剰発現マウスでの摂食・エネルギー消費調節機構
- Author(s)
  佐々木努、北住知也、天野剛介、菊池司、橋本博美、小林雅樹、北村忠弘
- Organizer
  第３２回日本肥満学会
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Pomc-Cre; Sirt1 conditional Knock-In Mice
- Author(s)
  佐々木　努、天野　剛介、北住　知也、菊池　司、小林　雅樹、北村　忠弘
- Organizer
  アメリカ糖尿用学会71st Scientific Sessions
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Conditional Knock-in of SIRT1 in AGRP or POMC
- Author(s)
  Tsutomu Sasaki, Tadahiro Kitamura
- Organizer
  ADA Research Symposium "Diabetes and the Brain"
- Place of Presentation
  Alexandria, Virginia, USA
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Sirt1 expression in AgRP and Pomc neurons
- Author(s)
  佐々木努、北住知也、天野剛介、菊池司、橋本博美、小林雅樹、北村忠弘
- Organizer
  Japan Neuroscience Society
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790270
[Presentation] Hypothalamic Sirt1 achieves negative energy balance by stimulating energy expenditure in POMC neurons and by suppressing food intake in AgRP neurons
- Author(s)
  佐々木努
- Organizer
  Keystone Symposia on Aging and Diseases of Aging
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790270

1. INUTSUKA Ayumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 中川崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 夜久圭介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 山中章弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 原田彰宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 松居翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小林和人

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# of Collaborated Products: 1 results
8. 井本正哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sasaki Tsutomu 佐々木 努

SASAKI Tsutomu 佐々木 努

Research Projects

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Co-Researchers

Elucidating how homeostasis is maintained through nutrition-based appetitePrincipal Investigator

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Elucidating neural circuit that regulates alcohol intake through metabolic signalingPrincipal Investigator

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Elucidating how the longevity gene SIRT1 regulate alcohol preference.Principal Investigator

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Elucidating the role of brain SIRT1, an integrator of external and internal environment, in regulating will and motivation.Principal Investigator

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Elucidating the neuronal regulation of food preferece; focusing on the longevity gene SIRT1Principal Investigator

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Hypothalamic Sirt1 and FoxO1 in energy balance regulationPrincipal Investigator

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代謝シグナルによる視床下部ＮＡＤ依存性脱アセチル化酵素ＳＩＲＴ１の制御機構の解明Principal Investigator

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Elucidation of the role of hypothalamic Sirt1 in energy balance regulation.Principal Investigator

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Investigation into the role of hypothalamic SIRT1 in regulating energy metabolism.Principal Investigator

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[Book] もっとよくわかる！食と栄養のサイエンス2021

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[Journal Article] Neuronal sirtl regulates macronutrient-based diet selection through fgf21 and oxytocin signalling in mice.2018

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[Journal Article] Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice.2014

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[Journal Article] Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via AgRP2010

Author(s)

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[Journal Article] Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via AgRP2010

Sasaki Tsutomu 佐々木努

SASAKI Tsutomu 佐々木努