OKAZAKI MIKIO 岡崎幹生

… Alternative Names

OKAZAKI Mikio 岡崎幹生

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Researcher Number	50467750
Other IDs
Affiliation (Current)	2022: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 岡山大学, 大学病院, 講師 2021: 岡山大学, 医歯薬学域, 准教授 2018 – 2019: 岡山大学, 大学病院, 助教 2017: 愛媛大学, 医学部附属病院, 助教 2011 – 2017: 愛媛大学, 医学部附属病院, 講師 … More 2009: Okayama University, レジデント 2009: Department of Clinical Research, National Hospital Organization Shikoku Cancer Center, 臨床研究部, 医師 2008: Okayama University, 医学部・歯学部附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Respiratory surgery / Immunology / Thoracic surgery / Basic Section 55040:Respiratory surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Respiratory surgery
Keywords	Principal Investigator 肺移植 / 虚血再灌流障害 / 心停止ドナー / 心停止ドナーからの肺移植 / 急性拒絶反応 / 慢性拒絶反応 / 閉塞性細気管支炎 / アポトーシス / 虚血再灌流霜害 / 血管内皮細胞 / S100 … More Except Principal Investigator … More 肺移植 / 虚血再灌流障害 / 肺癌 / NEDD8 / PD-L1 / 免疫チェックポイント阻害剤 / Nedd8 / 免疫チェックポイント / HMGB1 / 翻訳後修飾 / 腫瘍免疫 / 癌免疫 / タンパク質代謝 / Cullin / 血管内皮細胞 / ユビキチンリガーゼ / Cullin-3 / 酸化ストレス / 虚血再灌流 / モデルマウス / HMGB１ / 肺がん / 免疫チェックポイント阻害 / 肺癌細胞 / Neddylation / 非小細胞肺がん / がん微小環境 / がん関連線維芽細胞 / 高ヒスチジン糖タンパク質（HRG） / 早期移植肺機能不全（PGD） / 虚血再還流障害 / 体内肺還流法 Less

マトリセルラータンパク質阻害によるがん微小環境の破壊と抗腫瘍効果の検討
- Principal Investigator
  
  豊岡伸一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
抗炎症タンパク質HRGに着眼した肺虚血再灌流障害に対する新規治療法の開発
- Principal Investigator
  
  杉本誠一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
In-vivo lung perfusion as a novel treatment strategy for primary graft dysfunction after lung transplantation
- Principal Investigator
  
  三好健太郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
肺虚血再灌流障害におけるS100A8/A9の役割の解明と新しい治療法の開発Principal Investigator
- Principal Investigator
  
  岡崎幹生
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
組織障害性HMGB1に着眼した肺虚血再灌流障害に対する新規戦略の確立
- Principal Investigator
  
  大谷真二
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Ehime University
  Okayama University
肺癌における新規PD-L1発現調節機構とその免疫回避としての役割の解明
- Principal Investigator
  
  佐野由文
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Ehime University
心停止ドナーからの肺移植後虚血再灌流障害のトランスレーショナルリサーチと治療応用Principal Investigator
- Principal Investigator
  
  岡崎幹生
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Okayama University
Development of therapy of pulmonary ischemia-reperfusion injury targeting ubiquitin ligase
- Principal Investigator
  
  杉本龍士郎
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Ehime University
Inhibition of lung ischemia reperfusion injury by R-Spondin 3Principal Investigator
- Principal Investigator
  
  Okazaki Mikio
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
  Ehime University
Analysis of molecular mechanism of NEDD8-mediated regulation of PD-L1 in lung cancer
- Principal Investigator
  
  Yoshifumi Sano
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Ehime University
Endothelial dysfunction after lung transplantation with donation after cardiac death donorsPrincipal Investigator
- Principal Investigator
  
  Okazaki Mikio
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Ehime University
Mechanism and inhibition of ischemia reperfusion injury after lung transplantation from donation after cardiac deathPrincipal Investigator
- Principal Investigator
  
  OKAZAKI MIKIO
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Ehime University
Research of the Airway Apoptosis after Lung Transplant RejectionPrincipal Investigator
- Principal Investigator
  
  OKAZAKI Mikio
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Okayama University

All 2021 2019 2018 2017 2013 2009 2008

All Journal Article Presentation

[Journal Article] Protective effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice2021
- Author(s)
  Nakata Kentaro、Okazaki Mikio、Shimizu Dai、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Otani Shinji、Yamamoto Hiromasa、Sugimoto Seiichiro、Yamane Masaomi、Ousaka Daiki、Ohara Toshiaki、Matsukawa Akihiro、Nishibori Masahiro、Toyooka Shinichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 573 Pages: 164-170
- DOI
  10.1016/j.bbrc.2021.08.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09305, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K09176
[Journal Article] Costimulatory blockade-mediated lung allograft acceptance is abrogated by Over expression of Bcl-2 in the recipient.2009
- Author(s)
  Mikio Okazaki
- Journal Title
  
  Transplantation Proceedings 41
  
  Pages: 385-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790375
[Journal Article] Costimulatory blockade-mediated lung allograft acceptance is abrogated by overexpression of Bcl-2 in the recipient.2009
- Author(s)
  M. Okazaki, S. Sugimoto, J. Lai, C.G. Kornfeld, R.S. Hotchkiss, S.B. Richardson, W. Li, F.H. Kreisel, H.J. Huang, G.A. Patterson, A.S. Krupnick, A.E. Gelman, D. Kreisel.
- Journal Title
  
  Transplant Proc. 41(1)(in press)
  
  Pages: 385-7
- Data Source
  KAKENHI-PROJECT-20790375
[Presentation] Expression Analysis of Programmed Death-Ligand(PD-L)1 in Large Cell Neuroendocrine Carcinoma2019
- Author(s)
  Tomohisa Sakaue, Hirotomo Nakaoka, Mikio Okazaki, Hisayuki Shigematsu, Hironori Izutani, Yoshifumi Sano
- Organizer
  IASLC 2019 World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10791
[Presentation] 肺癌におけるPD-L1の発現制御メカニズムの解析2019
- Author(s)
  坂上倫久、中岡裕智、岡崎幹生、重松久之、杉本龍士郎、泉谷裕則、佐野由文
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10791
[Presentation] 肺癌におけるHeparin-binding Epidermal Growth factor（HB-EGF）の解析2018
- Author(s)
  坂上倫久、中岡裕智、藻利優、坂尾伸彦、岡崎幹生、重松久之、東山繁樹、佐野由文、泉谷裕則
- Organizer
  第59回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10791
[Presentation] 高悪性度神経内分泌肺腫瘍におけるPD-L1の発現解析2018
- Author(s)
  坂上倫久、中岡裕智、藻利優、岡崎幹生、重松久之、泉谷裕則、佐野由文
- Organizer
  第３５回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10791
[Presentation] 肺がん組織におけるProgrammed Death-Ligand 1（PD-L1）の発現とその制御メカニズムの解析2017
- Author(s)
  中岡裕智、坂上倫久、藻利優、坂尾伸彦、岡崎幹生、重松久之、倉田美恵、東山繁樹、佐野由文、泉谷裕則
- Organizer
  第34回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10791
[Presentation] 外科的切除した肺癌組織を用いたHeparin Binding EGF Like Growth Factor (HB-EGF)の解析2017
- Author(s)
  坂上倫久、中岡裕智、藻利優、坂尾伸彦、岡崎幹生、重松久之、佐野由文、泉谷裕則
- Organizer
  第34回日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10791
[Presentation] 肺癌細胞におけるProgrammed Death-Ligand1(PD-L1)の細胞内タンパク質代謝機序の解明2017
- Author(s)
  坂上倫久、藻莉優、坂尾伸彦、岡崎幹生、重松久之、東山繁樹、佐野由文、泉谷裕則
- Organizer
  第58回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10791
[Presentation] 心停止ドナーにおける血管内皮細胞の破綻2013
- Author(s)
  岡崎幹生
- Organizer
  第49回日本移植学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23592063
[Presentation] Costimulatory blockade-mediated lung allograft acceptance is abrogated by overexpression of Bcl-2 in the recipient.2008
- Author(s)
  Mikio Okazaki
- Organizer
  XXII International Congress of the Transplantation Society
- Place of Presentation
  オーストラリア・シドニー
- Year and Date
  2008-08-12
- Data Source
  KAKENHI-PROJECT-20790375

1. SANO Yoshifumi (60322228)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
2. 坂上倫久 (20709266)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
3. 豊岡伸一 (30397880)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. YAMANE Masaomi (20432643)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
5. 杉本誠一郎 (40570148)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
6. 中岡裕智 (30795464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
7. 阪口政清 (70379840)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 大谷真二 (10770779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 山本寛斉 (40467733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 三好健太郎 (50534773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 重松久之 (00645111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. 杉本龍士郎 (70549873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 木下理恵 (40518297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 王登莉 (40815693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 西堀正洋 (50135943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 塩谷俊雄 (90851246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 田中真 (20831308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 冨田秀太 (10372111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 枝園和彦 (30708079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 冨樫庸介 (80758326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 諏澤憲 (90839713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 逢坂大樹 (70839141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. DANIEL Kreisel

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. YOSHIDA Osamu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMAMOTO Sumiharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KAWAKAMI Tetsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. OTO Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKAZAKI MIKIO 岡崎 幹生

OKAZAKI Mikio 岡崎 幹生

Research Projects

Research Products

Co-Researchers

マトリセルラータンパク質阻害によるがん微小環境の破壊と抗腫瘍効果の検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

抗炎症タンパク質HRGに着眼した肺虚血再灌流障害に対する新規治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In-vivo lung perfusion as a novel treatment strategy for primary graft dysfunction after lung transplantation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺虚血再灌流障害におけるS100A8/A9の役割の解明と新しい治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

組織障害性HMGB1に着眼した肺虚血再灌流障害に対する新規戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺癌における新規PD-L1発現調節機構とその免疫回避としての役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心停止ドナーからの肺移植後虚血再灌流障害のトランスレーショナルリサーチと治療応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of therapy of pulmonary ischemia-reperfusion injury targeting ubiquitin ligase

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inhibition of lung ischemia reperfusion injury by R-Spondin 3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanism of NEDD8-mediated regulation of PD-L1 in lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Endothelial dysfunction after lung transplantation with donation after cardiac death donorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism and inhibition of ischemia reperfusion injury after lung transplantation from donation after cardiac deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research of the Airway Apoptosis after Lung Transplant RejectionPrincipal Investigator

Principal Investigator

Project Period (FY)

OKAZAKI MIKIO 岡崎幹生

OKAZAKI Mikio 岡崎幹生