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OKAZAKI MIKIO  岡崎 幹生

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OKAZAKI Mikio  岡崎 幹生

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Researcher Number 50467750
Other IDs
Affiliation (Current) 2022: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 岡山大学, 大学病院, 講師
2021: 岡山大学, 医歯薬学域, 准教授
2018 – 2019: 岡山大学, 大学病院, 助教
2017: 愛媛大学, 医学部附属病院, 助教
2011 – 2017: 愛媛大学, 医学部附属病院, 講師 … More
2009: Okayama University, レジデント
2009: Department of Clinical Research, National Hospital Organization Shikoku Cancer Center, 臨床研究部, 医師
2008: Okayama University, 医学部・歯学部附属病院, 医員 Less
Review Section/Research Field
Principal Investigator
Respiratory surgery / Immunology / Thoracic surgery / Basic Section 55040:Respiratory surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Except Principal Investigator
Basic Section 55040:Respiratory surgery-related / Respiratory surgery
Keywords
Principal Investigator
肺移植 / 虚血再灌流障害 / 心停止ドナー / 心停止ドナーからの肺移植 / 急性拒絶反応 / 慢性拒絶反応 / 閉塞性細気管支炎 / アポトーシス / 虚血再灌流霜害 / 血管内皮細胞 / S100 … More
Except Principal Investigator
… More 肺移植 / 虚血再灌流障害 / 肺癌 / NEDD8 / PD-L1 / 免疫チェックポイント阻害剤 / Nedd8 / 免疫チェックポイント / HMGB1 / 翻訳後修飾 / 腫瘍免疫 / 癌免疫 / タンパク質代謝 / Cullin / 血管内皮細胞 / ユビキチンリガーゼ / Cullin-3 / 酸化ストレス / 虚血再灌流 / モデルマウス / HMGB1 / 肺がん / 免疫チェックポイント阻害 / 肺癌細胞 / Neddylation / 非小細胞肺がん / がん微小環境 / がん関連線維芽細胞 / 高ヒスチジン糖タンパク質(HRG) / 早期移植肺機能不全(PGD) / 虚血再還流障害 / 体内肺還流法 Less
  • Research Projects

    (13 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (27 People)
  •  マトリセルラータンパク質阻害によるがん微小環境の破壊と抗腫瘍効果の検討

    • Principal Investigator
      豊岡 伸一
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Okayama University
  •  抗炎症タンパク質HRGに着眼した肺虚血再灌流障害に対する新規治療法の開発

    • Principal Investigator
      杉本 誠一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Okayama University
  •  In-vivo lung perfusion as a novel treatment strategy for primary graft dysfunction after lung transplantation

    • Principal Investigator
      三好 健太郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Okayama University
  •  肺虚血再灌流障害におけるS100A8/A9の役割の解明と新しい治療法の開発Principal Investigator

    • Principal Investigator
      岡崎 幹生
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Okayama University
  •  組織障害性HMGB1に着眼した肺虚血再灌流障害に対する新規戦略の確立

    • Principal Investigator
      大谷 真二
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
      Okayama University
  •  肺癌における新規PD-L1発現調節機構とその免疫回避としての役割の解明

    • Principal Investigator
      佐野 由文
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
  •  心停止ドナーからの肺移植後虚血再灌流障害のトランスレーショナルリサーチと治療応用Principal Investigator

    • Principal Investigator
      岡崎 幹生
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Okayama University
  •  Development of therapy of pulmonary ischemia-reperfusion injury targeting ubiquitin ligase

    • Principal Investigator
      杉本 龍士郎
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
  •  Inhibition of lung ischemia reperfusion injury by R-Spondin 3Principal Investigator

    • Principal Investigator
      Okazaki Mikio
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Okayama University
      Ehime University
  •  Analysis of molecular mechanism of NEDD8-mediated regulation of PD-L1 in lung cancer

    • Principal Investigator
      Yoshifumi Sano
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Ehime University
  •  Endothelial dysfunction after lung transplantation with donation after cardiac death donorsPrincipal Investigator

    • Principal Investigator
      Okazaki Mikio
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Ehime University
  •  Mechanism and inhibition of ischemia reperfusion injury after lung transplantation from donation after cardiac deathPrincipal Investigator

    • Principal Investigator
      OKAZAKI MIKIO
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Ehime University
  •  Research of the Airway Apoptosis after Lung Transplant RejectionPrincipal Investigator

    • Principal Investigator
      OKAZAKI Mikio
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Okayama University

All 2021 2019 2018 2017 2013 2009 2008

All Journal Article Presentation

  • [Journal Article] Protective effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice2021

    • Author(s)
      Nakata Kentaro、Okazaki Mikio、Shimizu Dai、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Otani Shinji、Yamamoto Hiromasa、Sugimoto Seiichiro、Yamane Masaomi、Ousaka Daiki、Ohara Toshiaki、Matsukawa Akihiro、Nishibori Masahiro、Toyooka Shinichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 573 Pages: 164-170

    • DOI

      10.1016/j.bbrc.2021.08.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09305, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K09176
  • [Journal Article] Costimulatory blockade-mediated lung allograft acceptance is abrogated by Over expression of Bcl-2 in the recipient.2009

    • Author(s)
      Mikio Okazaki
    • Journal Title

      Transplantation Proceedings 41

      Pages: 385-387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790375
  • [Journal Article] Costimulatory blockade-mediated lung allograft acceptance is abrogated by overexpression of Bcl-2 in the recipient.2009

    • Author(s)
      M. Okazaki, S. Sugimoto, J. Lai, C.G. Kornfeld, R.S. Hotchkiss, S.B. Richardson, W. Li, F.H. Kreisel, H.J. Huang, G.A. Patterson, A.S. Krupnick, A.E. Gelman, D. Kreisel.
    • Journal Title

      Transplant Proc. 41(1)(in press)

      Pages: 385-7

    • Data Source
      KAKENHI-PROJECT-20790375
  • [Presentation] Expression Analysis of Programmed Death-Ligand(PD-L)1 in Large Cell Neuroendocrine Carcinoma2019

    • Author(s)
      Tomohisa Sakaue, Hirotomo Nakaoka, Mikio Okazaki, Hisayuki Shigematsu, Hironori Izutani, Yoshifumi Sano
    • Organizer
      IASLC 2019 World Conference on Lung Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺癌におけるPD-L1の発現制御メカニズムの解析2019

    • Author(s)
      坂上倫久、中岡裕智、岡崎幹生、重松久之、杉本龍士郎、泉谷裕則、佐野由文
    • Organizer
      第60回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺癌におけるHeparin-binding Epidermal Growth factor(HB-EGF)の解析2018

    • Author(s)
      坂上倫久、中岡裕智、藻利優、坂尾伸彦、岡崎幹生、重松久之、東山繁樹、佐野由文、泉谷裕則
    • Organizer
      第59回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 高悪性度神経内分泌肺腫瘍におけるPD-L1の発現解析2018

    • Author(s)
      坂上倫久、中岡裕智、藻利優、岡崎幹生、重松久之、泉谷裕則、佐野由文
    • Organizer
      第35回日本呼吸器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺がん組織におけるProgrammed Death-Ligand 1(PD-L1)の発現とその制御メカニズムの解析2017

    • Author(s)
      中岡裕智、坂上倫久、藻利優、坂尾伸彦、岡崎幹生、重松久之、倉田美恵、東山繁樹、佐野由文、泉谷裕則
    • Organizer
      第34回日本呼吸器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 外科的切除した肺癌組織を用いたHeparin Binding EGF Like Growth Factor (HB-EGF)の解析2017

    • Author(s)
      坂上倫久、中岡裕智、藻利優、坂尾伸彦、 岡崎幹生、重松久之、佐野由文、泉谷裕則
    • Organizer
      第34回日本呼吸器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺癌細胞におけるProgrammed Death-Ligand1(PD-L1)の細胞内タンパク質代謝機序の解明2017

    • Author(s)
      坂上倫久、藻莉優、坂尾伸彦、岡崎幹生、 重松久之、東山繁樹、佐野由文、泉谷裕則
    • Organizer
      第58回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 心停止ドナーにおける血管内皮細胞の破綻2013

    • Author(s)
      岡崎幹生
    • Organizer
      第49回日本移植学会総会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Data Source
      KAKENHI-PROJECT-23592063
  • [Presentation] Costimulatory blockade-mediated lung allograft acceptance is abrogated by overexpression of Bcl-2 in the recipient.2008

    • Author(s)
      Mikio Okazaki
    • Organizer
      XXII International Congress of the Transplantation Society
    • Place of Presentation
      オーストラリア・シドニー
    • Year and Date
      2008-08-12
    • Data Source
      KAKENHI-PROJECT-20790375
  • 1.  SANO Yoshifumi (60322228)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 7 results
  • 2.  坂上 倫久 (20709266)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 7 results
  • 3.  豊岡 伸一 (30397880)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 4.  YAMANE Masaomi (20432643)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 5.  杉本 誠一郎 (40570148)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 6.  中岡 裕智 (30795464)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 7.  阪口 政清 (70379840)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  大谷 真二 (10770779)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 9.  山本 寛斉 (40467733)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  三好 健太郎 (50534773)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 11.  重松 久之 (00645111)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 12.  杉本 龍士郎 (70549873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  木下 理恵 (40518297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  王 登莉 (40815693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  西堀 正洋 (50135943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  塩谷 俊雄 (90851246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  田中 真 (20831308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  冨田 秀太 (10372111)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  枝園 和彦 (30708079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  冨樫 庸介 (80758326)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  諏澤 憲 (90839713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  逢坂 大樹 (70839141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  DANIEL Kreisel
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  YOSHIDA Osamu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  YAMAMOTO Sumiharu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  KAWAKAMI Tetsuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  OTO Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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