Mitsuishi Masanori 三石正憲

… Alternative Names

三石正憲ミツイシマサノリ

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Researcher Number	50468485
Affiliation (based on the past Project Information) *help	2018 – 2019: 慶應義塾大学, 医学部(信濃町), 助教 2017: 慶應義塾大学, 医学部, 助教 2016: 慶應義塾大学, 医学部(信濃町), 特任助教 2016: 慶應義塾大学, 医学部(信濃町), 助教 2015: 慶應義塾大学, 医学部, 研究員 2009 – 2010: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator General internal medicine(including psychosomatic medicine) / Kidney internal medicine / Metabolomics Except Principal Investigator General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator 骨格筋ミトコンドリア / ミトコンドリア / アミノレブリン酸 / 身体能力 / サルコペニア / 骨格筋 / 加齢 / ステロイド / エピゲノム / アミノ酸代謝 … More / IGF-1 / 内分泌学 / グレリン / 慢性腎不全 / アンジオテンシンII / 運動耐容能 / 骨格筋TORシグナル / 血管ホルモン … More Except Principal Investigator エピゲノム / 抗加齢医学 / 内分泌学 / グレリン / 骨格筋 / ミトコンドリア / サルコペニア / 身体能力 Less

Development of treatment for sarcopenia by repairing epigenomic alterations of skeletal muscle mitochondriaPrincipal Investigator
- Principal Investigator
  
  MITSUISHI Masanori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Keio University
Development of a new method for improving physical ability of chronic renal failure patients by correcting mitochondrial metabolism using electron carriersPrincipal Investigator
- Principal Investigator
  
  Mitsuishi Masanori
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Elucidation of epigenetic alteration associated with aging in the muscle and the recovery by hormonal therapy targeting the mitochondria
- Principal Investigator
  
  Miyashita Kazutoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Keio University
血管ホルモンによる耐糖能制御機構の解明 TORシグナルによる骨格筋脂質蓄積の関与Principal Investigator
- Principal Investigator
  
  三石正憲
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Keio University

All 2019 2018 2017 2016 2015 2013 2010 2009

All Journal Article Presentation

[Journal Article] Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid.2017
- Author(s)
  Fujii C, Miyashita K, Mitsuishi M, Sato M, Fujii K, Inoue H, Hagiwara A, Endo S, Uto A, Ryuzaki M, Nakajima M, Tanaka T, Tamaki M, Muraki A, Kawai T, Itoh H.
- Journal Title
  
  Scientific Reports
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460920
[Journal Article] Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid2017
- Author(s)
  Fujii Chikako、Miyashita Kazutoshi、Mitsuishi Masanori、Sato Masaaki、Fujii Kentaro、Inoue Hiroyuki、Hagiwara Aika、Endo Sho、Uto Asuka、Ryuzaki Masaki、Nakajima Motowo、Tanaka Tohru、Tamaki Masanori、Muraki Ayako、Kawai Toshihide、Itoh Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-017-03917-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09323, KAKENHI-PROJECT-17K09735, KAKENHI-PROJECT-17H06270
[Journal Article] Improvement of Physical Decline Through Combined Effects of Muscle Enhancement and Mitochondrial Activation by a Gastric Hormone Ghrelin in Male 5/6Nx CKD Model Mice.2015
- Author(s)
  Tamaki M, Miyashita K, Wakino S, Hagiwara A, Inoue H, Fujii K, Fujii C, Mitsuishi M, Muraki A, Hayashi K, Doi T, Itoh H.
- Journal Title
  
  Endocrinology
  
  Volume: 156 Pages: 3638-3648
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460920
[Journal Article] Improvement of physical performance in 5/6 nephrectomized CKD model mice by a gastric hormone ghrelin.2015
- Author(s)
  Tamaki M, Miyashita K, Wakino S, Hagiwara A, Inoue H, Fujii K, Fujii C, Mitsuishi M, Muraki A, Hayashi K, Doi T, Itoh H.
- Journal Title
  
  Endocrinology
  
  Volume: 156 Issue: 10 Pages: 3638-3648
- DOI
  10.1210/en.2015-1353
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19465, KAKENHI-PROJECT-26860644
[Journal Article] Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase.2013
- Author(s)
  Tamaki M, Miyashita K, Wakino S, Mitsuishi M, Hayashi K, Itoh H
- Journal Title
  
  Kindney International
  
  Volume: (印刷中) Issue: 6 Pages: 1330-1339
- DOI
  10.1038/ki.2013.473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J05579, KAKENHI-PROJECT-26460920
[Journal Article] ミトコンドリアと糖尿病2010
- Author(s)
  三石正憲, ほか
- Journal Title
  
  医学のあゆみ 232
  
  Pages: 740-745
- Data Source
  KAKENHI-PROJECT-21790881
[Journal Article] メタボリックシンドローム2009
- Author(s)
  三石正憲, ほか
- Journal Title
  
  日本臨牀 67
  
  Pages: 321-326
- Data Source
  KAKENHI-PROJECT-21790881
[Journal Article] Angiotensin II reduces muscle mitochondrial content and affects glycemic control.2009
- Author(s)
  Mitsuishi M, et al.
- Journal Title
  
  Diabetes 58
  
  Pages: 710-718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790881
[Presentation] ステロイド糖尿病モデルマウスにおけるDpp-4遺伝子発現変容の解析2019
- Author(s)
  宇都飛鳥, 宮下和季, 竜崎正毅, 押田卓磨, 三石正憲, 木内謙一郎, 伊藤裕
- Organizer
  第24回日本心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09323
[Presentation] 高血圧関連ヒストン脱アセチル化酵素Sirt3はDPP-4とGLP-1を介して糖代謝に関与する2018
- Author(s)
  宇都飛鳥、宮下和季、遠藤翔、井上博之、藤井健太郎、竜崎正毅、三石正憲、伊藤裕
- Organizer
  第41回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-17K09323
[Presentation] 長寿関連遺伝子Sirt3による糖代謝制御機構の解析2018
- Author(s)
  宇都飛鳥、宮下和季、遠藤翔、藤井千華子、萩原あいか、井上博之、藤井健太郎、竜崎正毅、三石正憲、伊藤裕
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09323
[Presentation] ミトコンドリア活性化分子であるアミノレブリン酸を用いたサルコペニア治療の試み2016
- Author(s)
  藤井千華子、宮下和季、藤井健太郎、井上博之、萩原あいか、田蒔昌憲、三石正憲、村木絢子、河合俊英、伊藤裕
- Organizer
  日本肥満治療学会学術集会
- Place of Presentation
  東京スクエアガーデン
- Data Source
  KAKENHI-PROJECT-15K19465
[Presentation] Improvement of physical performance in 5/6 nephrectomized CKD model mice through epigenetic modulation of PGC-1 expression by a gastric hormone ghrelin.2015
- Author(s)
  M Tamaki, K Miyashita, M. Mitsuishi, M Sato, A Hagiwara, H Inoue, K Fujii, H Itoh
- Organizer
  52nd ERA-EDTA congress
- Place of Presentation
  ロンドン(イギリス)
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19465
[Presentation] 骨格筋ミトコンドリア活性化によるサルコペニア治療と生活習慣病対策2015
- Author(s)
  宮下和季　藤井千華子　藤井健太郎　井上博之　萩原あいか　田蒔昌憲　村木絢子　三石正憲　伊藤裕
- Organizer
  第163回日本体力医学会総会
- Place of Presentation
  東京
- Year and Date
  2015-02-28
- Invited
- Data Source
  KAKENHI-PROJECT-26460920
[Presentation] 高蛋白食によるサルコペニア治療のピットフォールとグレリン・IGF-1の治療効果2015
- Author(s)
  宮下和季, 三石正憲, 村木絢子, 田蒔昌憲, 藤井千華子, 萩原あいか, 井上博之, 藤井健太郎, 伊藤裕
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ(東京都千代田区)
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K19465
[Presentation] マウスへの長期高蛋白食投与に伴う骨格筋ミトコンドリア量変化の解析2015
- Author(s)
  宮下和季, 三石正憲, 村木絢子, 田蒔昌憲, 藤井千華子, 萩原あいか, 井上博之, 藤井健太郎, 伊藤裕
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  ひめぎんホール（愛媛県松山市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26460920
[Presentation] 高血圧における臓器代謝異常ホルモンによるミトコンドリア制御と身体能力2015
- Author(s)
  宮下和季, 三石正憲, 田蒔昌憲, 萩原あいか, 井上博之, 藤井健太郎, 藤井千華子, 伊藤裕
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  ひめぎんホール(愛媛県松山市)
- Year and Date
  2015-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K19465
[Presentation] 高血圧における臓器代謝異常ホルモンによるミトコンドリア制御と身体能力2015
- Author(s)
  宮下和季, 三石正憲, 田蒔昌憲, 萩原あいか, 井上博之, 藤井健太郎, 藤井千華子, 伊藤裕
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  ひめぎんホール（愛媛県松山市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26460920
[Presentation] Improvement of physical decline through combined effects of muscle enhancement and mitochondrial activation by a gastric hormone ghrelin in male 5/6Nx CKD model mice.2015
- Author(s)
  田蒔昌憲, 宮下和季, 三石正憲, 村木絢子, 藤井千華子, 萩原あいか, 井上博之, 藤井健太郎, 伊藤裕
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  ひめぎんホール(愛媛県松山市)
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K19465
[Presentation] Angiotensin IIによる骨格筋ミトコンドリア制御と糖脂質代謝への関与2010
- Author(s)
  三石正憲, ほか
- Organizer
  第83回日本内分泌学会学術集会
- Place of Presentation
  京都
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21790881
[Presentation] アンジオテンシンIIの糖脂質代謝への影響と骨格筋ミトコンドリア2009
- Author(s)
  三石正憲, ほか
- Organizer
  第45回高血圧関連疾患モデル学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-21790881
[Presentation] アンジオテンシンIIによる骨格筋ミトコンドリア制御と耐糖能障害2009
- Author(s)
  三石正憲, ほか
- Organizer
  第46回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-04-12
- Data Source
  KAKENHI-PROJECT-21790881
[Presentation] アンジオテンシンIIによる骨格筋ミトコンドリア制御と糖脂質代謝制御2009
- Author(s)
  三石正憲, ほか
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21790881

1. Miyashita Kazutoshi (50378759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. ITOH Hiroshi (40252457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. TAMAKI Masanori (90528902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

Mitsuishi Masanori 三石 正憲

三石 正憲 ミツイシ マサノリ

Research Projects

Research Products

Co-Researchers

Development of treatment for sarcopenia by repairing epigenomic alterations of skeletal muscle mitochondriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new method for improving physical ability of chronic renal failure patients by correcting mitochondrial metabolism using electron carriersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of epigenetic alteration associated with aging in the muscle and the recovery by hormonal therapy targeting the mitochondria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管ホルモンによる耐糖能制御機構の解明 TORシグナルによる骨格筋脂質蓄積の関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid.2017

Author(s)

Journal Title

Data Source

[Journal Article] Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improvement of Physical Decline Through Combined Effects of Muscle Enhancement and Mitochondrial Activation by a Gastric Hormone Ghrelin in Male 5/6Nx CKD Model Mice.2015

Author(s)

Journal Title

Data Source

[Journal Article] Improvement of physical performance in 5/6 nephrectomized CKD model mice by a gastric hormone ghrelin.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ミトコンドリアと糖尿病2010

Author(s)

Journal Title

Data Source

[Journal Article] メタボリックシンドローム2009

Author(s)

Journal Title

Data Source

[Journal Article] Angiotensin II reduces muscle mitochondrial content and affects glycemic control.2009

Author(s)

Journal Title

Data Source

[Presentation] ステロイド糖尿病モデルマウスにおけるDpp-4遺伝子発現変容の解析2019

Author(s)

Organizer

Data Source

[Presentation] 高血圧関連ヒストン脱アセチル化酵素Sirt3はDPP-4とGLP-1を介して糖代謝に関与する2018

Author(s)

Organizer

Data Source

[Presentation] 長寿関連遺伝子Sirt3による糖代謝制御機構の解析2018

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリア活性化分子であるアミノレブリン酸を用いたサルコペニア治療の試み2016

Author(s)

Organizer

Place of Presentation

Mitsuishi Masanori 三石正憲

三石正憲ミツイシマサノリ

[Presentation] Improvement of physical performance in 5/6 nephrectomized CKD model mice through epigenetic modulation of PGC-1 expression by a gastric hormone ghrelin.2015

[Presentation] 高血圧における臓器代謝異常ホルモンによるミトコンドリア制御と身体能力2015

[Presentation] 高血圧における臓器代謝異常ホルモンによるミトコンドリア制御と身体能力2015