usui soichiro 薄井荘一郎

… Alternative Names

USUI Soichiro 薄井荘一郎

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Researcher Number	50507043
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, 医学系, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 金沢大学, 医学系, 准教授 2019 – 2023: 金沢大学, 附属病院, 講師 2016 – 2017: 金沢大学, 附属病院, 助教 2012 – 2015: 金沢大学, 大学病院, 助教 2008 – 2011: Kanazawa University, 附属病院, 助教
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related / Basic Section 90120:Biomaterials-related
Keywords	Principal Investigator 心不全 / 心臓リモデリング / 心肥大 / シグナル伝達 / ユビキチンプロテアソーム / NGFR陽性細胞 / 脂肪組織由来幹細胞 / CD271陽性細胞 / 間葉系幹細胞 / 血管リモデリング … More / CD271 / 肺高血圧 / 肝臓 / マイクロアレイ / ヘパトカイン / 心肝連関 / マトリックスメタロプロテアーゼ / タンパク分解 / 虚血性心疾患 / ユビキチンプロテオソーム / 心破裂 / 心筋梗塞 / 慢性心不全 / 遺伝子 / タンパク品質管理機構 / 循環器・高血圧 / アポトーシス … More Except Principal Investigator 拍動心筋分化 / 皮下脂肪間質細胞 / 機能解析 / 蛋白切断型バリアント / VUS / 遺伝性心筋症 / 遺伝性不整脈 / 不安定プラーク / 遺伝子導入 / 細胞治療 / 慢性心不全 / 拍動心筋細胞 / 拍動心筋文化 / 皮下脂肪組織間質細胞 / 再生治療 / 心筋分化 Less

Regulatory mechanisms of cardiac remodeling by NGFR-positive cellsPrincipal Investigator
- Principal Investigator
  
  薄井荘一郎
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa University
網羅的トランスクリプトーム解析による冠動脈プラーク不安定化予測のブレークスルー
- Principal Investigator
  
  坂田憲治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa University
遺伝性心筋症/不整脈に関与する病的バリアントの正確な決定と新規疾患発症機序の解明
- Principal Investigator
  
  林研至
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa University
皮下脂肪間質細胞の拍動心筋分化機構の解明と心筋再生治療への応用
- Principal Investigator
  
  高島伸一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kanazawa University
Development of therapeutic application of beating cardiomyocytes derived from human adipose tissue for treating heart failure
- Principal Investigator
  
  Takashima Shinichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kanazawa University
Development of a novel therapy for pulmonary hypertension targeting CD271-positive cellsPrincipal Investigator
- Principal Investigator
  
  USUI Soichiro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa University
Selenoprotein P, a liver-derived secretory protein, regulates pressure overload-induced cardiac remodelingPrincipal Investigator
- Principal Investigator
  
  Usui Soichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kanazawa University
Impacts of Protein Quality Control in Cardiac Remodeling after Myocardial InfarctionPrincipal Investigator
- Principal Investigator
  
  USUI Soichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa University
Role of Protein Quality Control in Cardiac RemodelingPrincipal Investigator
- Principal Investigator
  
  USUI Soichiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa University
Role of Muscle Atrophy F-box in the progression of Cardiac Remodeling.Principal Investigator
- Principal Investigator
  
  USUI Soichiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa University

[Journal Article] Impact of the severe familial hypercholesterolemia status on atherosclerotic risks2023
- Author(s)
  Tada H, Nohara A, Usui S, Sakata K, Kawashiri MA, Takamura M
- Journal Title
  
  Sci Rep
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-47147-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10485, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-21H03179
[Journal Article] Hypertrophic Cardiomyopathy Predicts Thromboembolism and Heart Failure in Patients With Nonvalvular Atrial Fibrillation　― A Prospective Analysis From the Hokuriku-Plus AF Registry ―2023
- Author(s)
  Tsuda Toyonobu、Hayashi Kenshi、Kato Takeshi、Kusayama Takashi、Nakagawa Yoichiro、Nomura Akihiro、Tada Hayato、Usui Soichiro、Sakata Kenji、Kawashiri Masa-aki、Fujino Noboru、Yamagishi Masakazu、Takamura Masayuki、on behalf of the Hokuriku-Plus AF Registry Investigators
- Journal Title
  
  Circ J
  
  Volume: 87 Issue: 12 Pages: 1790-1797
- DOI
  10.1253/circj.CJ-23-0418
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2023-11-24
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16052, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-20H03927
[Journal Article] Single-cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemia2023
- Author(s)
  Inoue Oto、Goten Chiaki、Hashimuko Daiki、Yamaguchi Kosei、Takeda Yusuke、Nomura Ayano、Ootsuji Hiroshi、Takashima Shinichiro、Iino Kenji、Takemura Hirofumi、Halurkar Manasi、Lim Hee-Woong、Hwa Vivian、Sanchez-Gurmaches Joan、Usui Soichiro、Takamura Masayuki
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 4 Issue: 12 Pages: 101337-101337
- DOI
  10.1016/j.xcrm.2023.101337
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08486
[Journal Article] Mechanisms of fever-induced QT prolongation and torsades de pointes in patients with KCNH2 mutation2023
- Author(s)
  Usuda K, Hayashi K, Nakajima T, Kurata Y, Cui S, Kusayama T, Tsuda T, Tada H, Kato T, Sakata K, Usui S, Fujino N, Tanaka Y, Kaneko Y, Kurabayashi M, Tange S, Saito T, Ohta K, Yamagishi M, Takamura M
- Journal Title
  
  Europace
  
  Volume: 25 Issue: 6
- DOI
  10.1093/europace/euad161
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06845, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-21K08075, KAKENHI-PROJECT-20H03927
[Journal Article] The utility of zebrafish cardiac arrhythmia model to predict the pathogenicity of KCNQ1 variants2023
- Author(s)
  Cui Shihe、Hayashi Kenshi、Nomura Akihiro、et al.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 177 Pages: 50-61
- DOI
  10.1016/j.yjmcc.2023.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17110, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-21K08075, KAKENHI-PROJECT-20H03927
[Journal Article] Important Role of Endogenous Nerve Growth Factor Receptor in the Pathogenesis of Hypoxia-Induced Pulmonary Hypertension in Mice2023
- Author(s)
  Goten Chiaki、Usui Soichiro、Takashima Shin-ichiro、Inoue Oto、Yamaguchi Kosei、Hashimuko Daiki、Takeda Yusuke、Nomura Ayano、Sakata Kenji、Kaneko Shuichi、Takamura Masayuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 3 Pages: 1868-1868
- DOI
  10.3390/ijms24031868
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-19K17670
[Journal Article] Therapeutic angiogenesis for patients with no-option critical limb ischemia by adipose-derived regenerative cells: TACT-ADRC multicenter trial2022
- Author(s)
  Shimizu Yuuki、Kondo Kazuhisa、Takashima Shinichiro、Inoue Oto、Usui Soichiro、Takamura MasayukiMitsukawa Nobuyuki、Akita Shinsuke、Ebisawa Soichiro、the TACT-ADRC multicenter trial Group
- Journal Title
  
  Angiogenesis
  
  Volume: 25 Issue: 4 Pages: 535-546
- DOI
  10.1007/s10456-022-09844-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-21H02911, KAKENHI-PROJECT-20K08401
[Journal Article] Effect of pulmonary vein isolation on the relationship between left atrial reverse remodeling and sympathetic nerve activity in patients with atrial fibrillation2022
- Author(s)
  Mukai Yusuke、Murai Hisayoshi、Hamaoka Takuto、Sugimoto Hiroyuki、Inoue Oto、Goten Chiaki、Kusayama Takashi、Takashima Shin-ichiro、Kato Takeshi、Usui Soichiro、Sakata Kenji、Takata Shigeo、Takamura Masayuki
- Journal Title
  
  Clinical Autonomic Research
  
  Volume: 32 Issue: 4 Pages: 229-235
- DOI
  10.1007/s10286-022-00873-2
- Data Source
  KAKENHI-PROJECT-19K08486
[Journal Article] Early diagnosis and treatments in childhood are associated with better prognosis in patients with familial hypercholesterolemia2022
- Author(s)
  Tada Hayato、Kojima Nobuko、Yamagami Kan、Nomura Akihiro、Nohara Atsushi、Usui Soichiro、Sakata Kenji、Takamura Masayuki、Kawashiri Masa-aki
- Journal Title
  
  American Journal of Preventive Cardiology
  
  Volume: 12 Pages: 100434-100434
- DOI
  10.1016/j.ajpc.2022.100434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-17K09859
[Journal Article] Eggplant-Like Coronary Aneurysm With Massive Thrombus2022
- Author(s)
  Yamagami Kan、Tada Hayato、Sakata Kenji、Usui Soichiro、Kawashiri Masa-aki、Takamura Masayuki
- Journal Title
  
  Circulation Reports
  
  Volume: 4 Issue: 2 Pages: 107-108
- DOI
  10.1253/circrep.CR-21-0149
- NAID
  130008159213
- ISSN
  2434-0790
- Year and Date
  2022-02-10
- Language
  English
- Data Source
  KAKENHI-PROJECT-19K08486
[Journal Article] Case Report: Myocarditis Associated With COVID-19 mRNA Vaccination Following Myocarditis Associated With Campylobacter Jejuni2022
- Author(s)
  Kojima Nobuko、Tada Hayato、Okada Hirofumi、Yoshida Shohei、Sakata Kenji、Usui Soichiro、Ikeda Hiroko、Okajima Masaki、Kawashiri Masa-aki、Takamura Masayuki
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 9
- DOI
  10.3389/fcvm.2022.837759
- Data Source
  KAKENHI-PROJECT-19K08486
[Journal Article] Association between Cardiovascular Health and Incident Atrial Fibrillation in the General Japanese Population Aged ?40 Years2021
- Author(s)
  Nishikawa Tetsuo、Tanaka Yoshihiro、Tada Hayato、Tsuda Toyonobu、Kato Takeshi、Usui Soichiro、Sakata Kenji、Hayashi Kenshi、Kawashiri Masa-aki、Hashiba Atsushi、Takamura Masayuki
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 9 Pages: 3201-3201
- DOI
  10.3390/nu13093201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-21K08075
[Journal Article] Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy2021
- Author(s)
  Sakai Y, Fukunishi S, Takamura M, Kawaguchi K, Inoue O, Usui S, Takashima S, Seki A, Asai A, Tsuchimoto Y, Nasti A, Bich Ho TT, Imai Y, Yoshimura K, Murayama T, Yamashita T, Arai K, Yamashita T, Mizukoshi E, Honda M, Wada T, Harada K, Higuchi K, Kaneko S.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 18 Pages: 97-101
- DOI
  10.1016/j.reth.2021.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-17H01886, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-21K07940
[Journal Article] Different Responses of Muscle Sympathetic Nerve Activity to Dapagliflozin Between Patients With Type 2 Diabetes With and Without Heart Failure2021
- Author(s)
  Hamaoka Takuto、Murai Hisayoshi、Hirai Tadayuki、Sugimoto Hiroyuki、Mukai Yusuke、Inoue Oto、Takashima Shinichiro、Kato Takeshi、Takata Shigeo、Usui Soichiro、Sakata Kenji、Kawashiri Masa‐Aki、Takamura Masayuki
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 10 Issue: 22
- DOI
  10.1161/jaha.121.022637
- Data Source
  KAKENHI-PROJECT-19K08486
[Journal Article] Impact of sinus rhythm maintenance on major adverse cardiac and cerebrovascular events after catheter ablation of atrial fibrillation: insights from AF frontier ablation registry2021
- Author(s)
  Usuda Keisuke, Kato Takeshi, Tsuda Toyonobu, et al. On behalf of the AF Ablation Frontier Registry
- Journal Title
  
  Heart and Vessels
  
  Volume: 37 Issue: 2 Pages: 327-336
- DOI
  10.1007/s00380-021-01929-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08099, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-20K08501, KAKENHI-PROJECT-21K08075, KAKENHI-PROJECT-21K08125
[Journal Article] Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair2021
- Author(s)
  Yano M, Honda M, Wada T, Kaneko S, Sakai Y.（ほか17名、19番目）
- Journal Title
  
  Regenerative Therapy
  
  Volume: 18 Pages: 497-507
- DOI
  10.1016/j.reth.2021.11.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-20K08327, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20K17017
[Journal Article] Prevalence and Impact of Apolipoprotein E7 on LDL Cholesterol Among Patients With Familial Hypercholesterolemia.2021
- Author(s)
  Tada H, Yamagami K, Kojima N, Shibayama J, Nishikawa T, Okada H, Nomura A, Usui S, Sakata K, Takamura M, Kawashiri MA.
- Journal Title
  
  Front Cardiovasc Med.
  
  Volume: 8 Pages: 625852-625852
- DOI
  10.3389/fcvm.2021.625852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08553, KAKENHI-PROJECT-19K08486
[Journal Article] Circulating nerve growth factor receptor positive cells are associated with severity and prognosis of pulmonary arterial hypertension2021
- Author(s)
  Chiaki Goten, Soichiro Usui, Shin-Ichiro Takashima, Oto Inoue, Hirofumi Okada, Masaya Shimojima, Kenji Sakata, Masaaki Kawashiri, Shuichi Kaneko, Masayuki Takamura
- Journal Title
  
  Pulmonary circulation
  
  Volume: 11(1) Issue: 1 Pages: 1-11
- DOI
  10.1177/2045894021990525
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17670, KAKENHI-PROJECT-19K08486
[Journal Article] Early Detection of Symptom Exacerbation in Patients With SARS-CoV-2 Infection Using the Fitbit Charge 3 (DEXTERITY): Pilot Evaluation2021
- Author(s)
  Yamagami Kan、Nomura Akihiro、Kometani Mitsuhiro、Shimojima Masaya、Sakata Kenji、Usui Soichiro、Furukawa Kenji、Takamura Masayuki、Okajima Masaki、Watanabe Kazuyoshi、Yoneda Takashi
- Journal Title
  
  JMIR Formative Research
  
  Volume: 5 Issue: 9 Pages: e30819-e30819
- DOI
  10.2196/30819
- Data Source
  KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-19K18003
[Journal Article] Diabetes impairs the angiogenic capacity of human adipose-derived stem cells by reducing the CD271+ subpopulation in adipose tissue2019
- Author(s)
  Inoue Oto、Usui Soichiro、Takashima Shin-ichiro、Nomura Ayano、Yamaguchi Kosei、Takeda Yusuke、Goten Chiaki、Hamaoka Takuto、Ootsuji Hiroshi、Murai Hisayoshi、Kaneko Shuichi、Takamura Masayuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 517 Issue: 2 Pages: 369-375
- DOI
  10.1016/j.bbrc.2019.07.081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08486, KAKENHI-PLANNED-17H06393
[Journal Article] Endogenous Selenoprotein P, a Liver-Derived Secretory Protein, Mediates Myocardial Ischemia/Reperfusion Injury in Mice.2018
- Author(s)
  Chikata A, Kato T, Usuda K, Fujita S, Maruyama M, Nagata Y, Sakagami S, Kanamori N, Yaegashi T, Saeki T, Kusayama T, Usui S, Furusho H, Kaneko S, Takamura M.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 3 Pages: 878-878
- DOI
  10.3390/ijms19030878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-15K09135, KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H04199
[Journal Article] Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6.2017
- Author(s)
  Ohkura SI, Usui S, Takashima SI, Takuwa N, Yoshioka K, Okamoto Y, Inagaki Y, Sugimoto N, Kitano T, Takamura M, Wada T, Kaneko S, Takuwa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 8 Pages: e0182329-e0182329
- DOI
  10.1371/journal.pone.0182329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-15K09135, KAKENHI-PROJECT-15K10970, KAKENHI-PROJECT-17H04166
[Journal Article] β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice2017
- Author(s)
  Pongkan Wanpitak、Takatori Osamu、Ni Yinhua、Xu Liang、Nagata Naoto、Chattipakorn Siriporn C.、Usui Soichiro、Kaneko Shuichi、Takamura Masayuki、Sugiura Minoru、Chattipakorn Nipon、Ota Tsuguhito
- Journal Title
  
  Mol Nutr Food Res.
  
  Volume: 61 Issue: 10 Pages: 1601077-1601077
- DOI
  10.1002/mnfr.201601077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09135
[Journal Article] Long-Term Administration of Eicosapentaenoic Acid Improves Post-Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization.2017
- Author(s)
  Takamura M, Kurokawa K, Ootsuji H, Inoue O, Okada H, Nomura A, Kaneko S, Usui S.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 21 Issue: 2
- DOI
  10.1161/jaha.116.004560
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-15K09135
[Journal Article] Adipose-derived regenerative cells exert beneficial effects on systemic responses following myocardial ischemia/reperfusion.2016
- Author(s)
  Takamura M, Usui S, Inoue O, Ootsuji H, Takashima SI, Nomura A, Kato T, Murai H, Furusho H, Sakai Y, Kaneko S.
- Journal Title
  
  Cardiol J
  
  Volume: 23 Issue: 6 Pages: 685-693
- DOI
  10.5603/cj.a2016.0061
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460995, KAKENHI-PROJECT-15K09135, KAKENHI-PROJECT-16K09425
[Journal Article] Sodium 4-Phenylbutyrate Attenuates Myocardial Reperfusion Injury by Reducing the Unfolded Protein Response.2016
- Author(s)
  Takatori O, Usui S, Okajima M, Kaneko S, Ootsuji H, Takashima SI, Kobayashi D, Murai H, Furusho H, Takamura M.
- Journal Title
  
  J Cardiovasc Pharmacol Ther.
  
  Volume: 22 Issue: 3 Pages: 283-292
- DOI
  10.1177/1074248416679308
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09135, KAKENHI-PROJECT-26462750
[Journal Article] MuRF1 negatively regulates pathological cardiac hypertrophy through downregulation of calcineurin A2014
- Author(s)
  M.Yokota（他8名、7番目） et al
- Journal Title
  
  Circ Heart Fail
  
  Volume: 7 Issue: 3 Pages: 479-490
- DOI
  10.1161/circheartfailure.113.000713
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390169, KAKENHI-PROJECT-24591092, KAKENHI-PROJECT-25293144, KAKENHI-PROJECT-25461049, KAKENHI-PROJECT-26461126
[Journal Article] Rho-kinase activation in leukocytes plays a pivotal role in myocardial ischemia/reperfusion injury2014
- Author(s)
  Kitano K, Usui S, Ootsuji H, Takashima S, Kobayashi D, Murai H, Furusho H, Nomura A, Kaneko S, Takamura M.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 3 Pages: e92242-e92242
- DOI
  10.1371/journal.pone.0092242
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591092, KAKENHI-PROJECT-25461049, KAKENHI-PROJECT-25860590
[Journal Article] Hemodynamic collapse induced by general anesthesia in a patient with an unruptured thoracic aortic aneurysm: a case report2013
- Author(s)
  Inoue, O, Murai, H, Kaneko, S, Usui, S, Furusho, H, Takamura, M
- Journal Title
  
  BMC CARDIOVASCULAR DISORDERS
  
  Volume: 13 Issue: 1 Pages: 122-122
- DOI
  10.1186/1471-2261-13-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591092
[Journal Article] Adipose tissue derived stromal stem cell therapy in murine ConA-derived hepatitis is dependent on myeloid-lineage and CD4+ T-cell suppression.2013
- Author(s)
  Higashimoto M, Sakai Y, Takamura M, Usui S, Nasti A, Yoshida K, Seki A, Komura T, Honda M, Wada T, Furuichi K, Ochiya T, Kaneko S.
- Journal Title
  
  Eur J Immunol
  
  Volume: 43 Issue: 11 Pages: 2956-68
- DOI
  10.1002/eji.201343531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590968, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24591092, KAKENHI-PROJECT-25670269
[Journal Article] Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model2013
- Author(s)
  A Seki, S Y akai, T Komura, A Nasti, K Yoshida, M Higashimoto, M Honda, S Usui, M Takamura, T Takamura, T Ochiya, K Furuichi, T Wada, S Kaneko
- Journal Title
  
  Hepatology
  
  Volume: 58(3) Issue: 3 Pages: 1133-42
- DOI
  10.1002/hep.26470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23590968, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24591092, KAKENHI-PROJECT-25670269
[Journal Article] Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heart.2013
- Author(s)
  Hariharan N, Ikeda Y, Hong C, Alcendor RR, Usui S, Gao S, Maejima Y, Sadoshima J.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 1 Pages: 51632-51632
- DOI
  10.1371/journal.pone.0051632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591092
[Journal Article] Benidipine reduces ischemiareperfusion-induced systemicoxidative stress through suppressionof aldosterone production in mice2012
- Author(s)
  Ohtani K, Usui S, and other 7
- Journal Title
  
  Hypertens Res
  
  Volume: 35 Issue: 3 Pages: 287-94
- DOI
  10.1038/hr.2011.183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790697
[Journal Article] Endogenous muscle atrophy F-boxmediates pressure overload-inducedcardiac hypertrophy throughregulation of nuclear factor-kappaB2012
- Author(s)
  Usui S, Maejima Y, and other 8
- Journal Title
  
  Circ Res
  
  Volume: 109 Issue: 2 Pages: 161-71
- DOI
  10.1161/circresaha.110.238717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790697
[Journal Article] Altered Hepatic Gene Expression Profiles Associated with Myocardial Ischemia.2010
- Author(s)
  Ohtsuji H, Honda M, Usui S, other 7
- Journal Title
  
  Circulation Cardiovas Genet. 3
  
  Pages: 194-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890085
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.2010
- Author(s)
  Takuwa N, Ohkura SI, Usui S, other 18
- Journal Title
  
  Cardiovasc Res. 85
  
  Pages: 484-493
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890085
[Presentation] Hepatokine Selenoprotein P Mediated Pressure Overload-Induced Cardiac Dysfunction2024
- Author(s)
  Soichiro Usui
- Organizer
  The 88th Annual Scientific Meeting of the Japanease Circulation Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08486
[Presentation] Hepatokine selenoprotein P has an important role in cardiac remodeling2023
- Author(s)
  Soichiro Usui
- Organizer
  ESC 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08486
[Presentation] 遺伝子導入脂肪組織幹細胞による新しい心筋再生治療の開発2021
- Author(s)
  高島伸一郎、薄井荘一郎、高村雅之
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K12681
[Presentation] Circulating CD271 is Associated with the Severity of Pulmonary Arterial Hypertension2019
- Author(s)
  Chiaki Goten, Soichiro Usui, Oto Inoue, Shin-ichiro Takashima, and Masayuki Takamura
- Organizer
  American Heart Association Scientific Sessions 2019, Nov. 16-19, 2019 (Philadelphia, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08486
[Presentation] Endogenous selenoprotein P mediates pressure overload-induced cardiac hypertrophy2017
- Author(s)
  Soichiro Usui
- Organizer
  ESC2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09135
[Presentation] Endogenous Selenoprotein P is a Positive Mediator of Cardiac Remodeling in Response　to Pressure Overload2017
- Author(s)
  Usui S
- Organizer
  The 81st Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Ishikawa Ongakudo, Kanazawa
- Year and Date
  2017-03-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09135
[Presentation] Muscle Specific E3 Ligase MAFbx Controls Cardiac Rupture after Myocardial Infarction in Mice2016
- Author(s)
  Akio Chikata, Soichiro Usui、Shinichiro Takashima、Takeshi Kato、Hisayoshi Murai、Hiroshi Furusho、Shuichi Kaneko、Junichi Sadoshima、Masayuki Takamura
- Organizer
  日本循環器学会　学術集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K09135
[Presentation] Adipose Tissue-derived Stromal Cells Exert Beneficial Effect to Systemic Responses Following Myocardial Ischemia Reperfusion2016
- Author(s)
  Soichiro Usui 、Oto Inoue、Shinichiro Takashima、Hiroshi Ohtsuji、Hisayoshi Murai、Shuichi Kaneko、Masayuki Takamura
- Organizer
  日本循環器学会　学術集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K09135
[Presentation] Endogenous MAFbx Mediates Cardiac Rupture After Myocardial Infarction in Mice2015
- Author(s)
  Akio Chikata, Soichiro Usui
- Organizer
  AHA2015
- Place of Presentation
  USA フロリダ
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09135
[Presentation] Rho-kinase Mediates Myocardial Ischemia Reperfusion Injury by RegUlating Leukocyte Responses in Mice2011
- Author(s)
  Usui S, Kitano K, other 2
- Organizer
  AHA 2011
- Place of Presentation
  Orange County Convention Cente (USA)
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-22790697
[Presentation] Rho-kinaseMediates Myocardial Ischemia Reperfusion Injury by Regulating Leukocyte Responses in Mice2011
- Author(s)
  Usui S, Kitano K, other 2
- Organizer
  AmericanHeart Association 2011
- Place of Presentation
  Orange County Convention Cente(USA)
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-22790697
[Presentation] Muscle Atrophy F-box Inhibited Pressure Overload Induced Cardiac Hypertrophy through the Activation of NFκ-B Pathway.2009
- Author(s)
  Usui. S
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-20890085
[Presentation] Muscle Atrophy F-box Inhibited Pressure Overload Induced Cardiac Hypertrophy through the Activation of NF_K-B Pathway2009
- Author(s)
  Soiochiro Usui
- Organizer
  日本循環器学会
- Place of Presentation
  大阪
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-20890085
[Presentation] MAFbx regulates cardiac rupture in mice with myocardial infarction
- Author(s)
  Chikada, A; Usui, S; Kaneko, S; Sadoshima, J; Takamura, M
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場（大阪）
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-24591092
[Presentation] Muscle atrophy F-box (MAFbx) regulates neointimal formation during vascular remodeling in mice
- Author(s)
  Kashimoto, M; Usui, S; Kusayama, T; Kitano, T; Kaneko, S; Sadoshima, J; Takamura, M
- Organizer
  ESC2014
- Place of Presentation
  Fira de Barcelona （スペイン　バルセロナ）
- Year and Date
  2014-08-31 – 2014-09-02
- Data Source
  KAKENHI-PROJECT-24591092
[Presentation] Sphingosine 1-Phosphate Receptor 1 Signaling in Cardiac Fibroblaste Regulates Cardiac Hypertrophy and Fibrosis Through Angiotensin II and Interleukin-6
- Author(s)
  Usui, S, Okura, S, Takashima, S, Takamura M, Kaneko S, Takuwa Y
- Organizer
  AHA2013
- Place of Presentation
  ジェイワールドコンベンションセンター　（米国　ダラス）
- Data Source
  KAKENHI-PROJECT-24591092

1. Takashima Shinichiro (60547165)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. 坂田憲治 (20456411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 林研至 (00422642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 吉田昌平 (30623657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 野村章洋 (30707542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 藤野陽 (40361993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAMURA Toshinari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 川尻剛照

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 多田隼人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 酒井佳夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 高村雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 中島忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 金古善明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 加藤武史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 横田充弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 五天千明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 金子周一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

usui soichiro 薄井 荘一郎

USUI Soichiro 薄井 荘一郎

Research Projects

Research Products

Co-Researchers

Regulatory mechanisms of cardiac remodeling by NGFR-positive cellsPrincipal Investigator

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網羅的トランスクリプトーム解析による冠動脈プラーク不安定化予測のブレークスルー

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遺伝性心筋症/不整脈に関与する病的バリアントの正確な決定と新規疾患発症機序の解明

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皮下脂肪間質細胞の拍動心筋分化機構の解明と心筋再生治療への応用

Principal Investigator

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Development of therapeutic application of beating cardiomyocytes derived from human adipose tissue for treating heart failure

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Development of a novel therapy for pulmonary hypertension targeting CD271-positive cellsPrincipal Investigator

Principal Investigator

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Selenoprotein P, a liver-derived secretory protein, regulates pressure overload-induced cardiac remodelingPrincipal Investigator

Principal Investigator

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Impacts of Protein Quality Control in Cardiac Remodeling after Myocardial InfarctionPrincipal Investigator

Principal Investigator

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Role of Protein Quality Control in Cardiac RemodelingPrincipal Investigator

Principal Investigator

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Role of Muscle Atrophy F-box in the progression of Cardiac Remodeling.Principal Investigator

Principal Investigator

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[Journal Article] Impact of the severe familial hypercholesterolemia status on atherosclerotic risks2023

Author(s)

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DOI

Data Source

[Journal Article] Hypertrophic Cardiomyopathy Predicts Thromboembolism and Heart Failure in Patients With Nonvalvular Atrial Fibrillation ― A Prospective Analysis From the Hokuriku-Plus AF Registry ―2023

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[Journal Article] Single-cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemia2023

Author(s)

usui soichiro 薄井荘一郎

USUI Soichiro 薄井荘一郎

[Journal Article] Hypertrophic Cardiomyopathy Predicts Thromboembolism and Heart Failure in Patients With Nonvalvular Atrial Fibrillation　― A Prospective Analysis From the Hokuriku-Plus AF Registry ―2023