okamoto akihisa 岡本明久

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OKAMOTO Akihisa 岡本明久

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Researcher Number	50509479
Affiliation (Current)	2025: 関西医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2021: 関西医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related
Keywords	Principal Investigator 代謝 / HIF-1 / 低酸素誘導性因子1 / ミトコンドリア / ROS / プロポフォール / ATP / 酸素代謝 / 麻酔薬 / 細胞内代謝 … More / 活性酸素種 / 局所麻酔薬 / ネクローシス / アポトーシス / 酸素 / リドカイン / プロポフォール注入症候群 Less

itochondria as target cell organelles of anesthetics and exploration of intracellular oxygen energy metabolismPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Akihisa
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kansai Medical University
Suppression of propofol-induced mitochondria-dependent cytotoxicity by HIF-1 activationPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Akihisa
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kansai Medical University

All 2019 2018

All Journal Article

[Journal Article] Real-time diagnostic analysis of MinION-based metagenomic sequencing in clinical microbiology evaluation: a case report2019
- Author(s)
  Hiromasa Tanaka, Yoshiyuki Matsuo, So Nakagawa, Kenichiro Nishi, Akihisa Okamoto, Shinichi Kai, Teppei Iwai, Yoshiteru Tabata, Takeshi Tajima, Yuji Komatsu, Motohiko Satoh, Kirill Kryukov, Tadashi Imanishi, Kiichi Hirota
- Journal Title
  
  JA Clinical Reports
  
  Volume: 5 Issue: 1 Pages: 24-24
- DOI
  10.1186/s40981-019-0244-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07123, KAKENHI-PROJECT-16K10975, KAKENHI-PROJECT-19K09339, KAKENHI-PROJECT-18K16501
[Journal Article] Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner2018
- Author(s)
  Sumi Chisato、Okamoto Akihisa、Tanaka Hiromasa、Nishi Kenichiro、Kusunoki Munenori、Shoji Tomohiro、Uba Takeo、Matsuo Yoshiyuki、Adachi Takehiko、Hayashi Jun-Ichi、Takenaga Keizo、Hirota Kiichi
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 2 Pages: e0192796-e0192796
- DOI
  10.1371/journal.pone.0192796
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K10974, KAKENHI-PROJECT-16K10975, KAKENHI-PROJECT-15K10551, KAKENHI-PROJECT-16K15682, KAKENHI-PROJECT-18K08877, KAKENHI-PROJECT-18K16501
[Journal Article] Suppression of mitochondrial oxygen metabolism mediated by the transcription factor HIF-1 alleviates propofol-induced cell toxicity2018
- Author(s)
  Sumi Chisato、Okamoto Akihisa、Tanaka Hiromasa、Kusunoki Munenori、Shoji Tomohiro、Uba Takeo、Adachi Takehiko、Iwai Teppei、Nishi Kenichiro、Harada Hiroshi、Bono Hidemasa、Matsuo Yoshiyuki、Hirota Kiichi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8987-8987
- DOI
  10.1038/s41598-018-27220-8
- NAID
  120006539570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08874, KAKENHI-PROJECT-18K08877, KAKENHI-PROJECT-18K16501, KAKENHI-PROJECT-16K10974, KAKENHI-PROJECT-16K10975

1. クリュコフキリル

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 竹永啓三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 廣田喜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 岩井鉄平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

okamoto akihisa 岡本明久

OKAMOTO Akihisa 岡本明久

Research Projects

Research Products

Co-Researchers

itochondria as target cell organelles of anesthetics and exploration of intracellular oxygen energy metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Suppression of propofol-induced mitochondria-dependent cytotoxicity by HIF-1 activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Real-time diagnostic analysis of MinION-based metagenomic sequencing in clinical microbiology evaluation: a case report2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of mitochondrial oxygen metabolism mediated by the transcription factor HIF-1 alleviates propofol-induced cell toxicity2018

Author(s)

Journal Title

DOI

NAID

Data Source

okamoto akihisa 岡本 明久

OKAMOTO Akihisa 岡本 明久

Research Projects

Research Products

Co-Researchers

itochondria as target cell organelles of anesthetics and exploration of intracellular oxygen energy metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Suppression of propofol-induced mitochondria-dependent cytotoxicity by HIF-1 activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Real-time diagnostic analysis of MinION-based metagenomic sequencing in clinical microbiology evaluation: a case report2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of mitochondrial oxygen metabolism mediated by the transcription factor HIF-1 alleviates propofol-induced cell toxicity2018

Author(s)

Journal Title

DOI

NAID

Data Source

okamoto akihisa 岡本明久

OKAMOTO Akihisa 岡本明久