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IRIE Koichiro  入江 浩一郎

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Koichiro Irie  入江 浩一郎

IRIE Kouichiro  入江 浩一郎

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Researcher Number 50509594
Other IDs
Affiliation (Current) 2025: 長崎大学, 医歯薬学総合研究科(歯学系), 教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 神奈川歯科大学, 歯学部, 准教授
2021: 明海大学, 歯学部, 講師
2015 – 2017: 岡山大学, 大学病院, 講師
2014: 愛知学院大学, 歯学部, 講師
2012: 岡山大学, 岡山大学病院, 医員
2010: Okayama University, 岡山大学病院, 医員
2009: Okayama University, 病院, 医員
Review Section/Research Field
Principal Investigator
Social dentistry / Basic Section 57080:Social dentistry-related
Except Principal Investigator
Basic Section 57080:Social dentistry-related / Social dentistry
Keywords
Principal Investigator
口腔常在菌 / 歯周組織 / 免疫応答 / LPS / 3型自然リンパ球 / 口腔粘膜免疫 / IgA / 自然免疫 / 自然リンパ球 / 感染症 … More / 免疫学 / 歯学 / CD4+T細胞 / 常在菌 / 歯周病 / host response / periodontitis / 宿主 / 歯槽骨吸収 / 加齢 / 口臭起因物質 / ラット / 揮発性化合物 / 口臭 … More
Except Principal Investigator
唾液 / 口腔機能 / 分泌型免疫グロブリンA / 食生活指導 / 歯周病 / 生活習慣 / 口腔の健康状態 / 終末糖化産物 / アミロイドβ / 咬合異常 / アルツハイマー病 / 歯学 Less
  • Research Projects

    (8 results)
  • Research Products

    (42 results)
  • Co-Researchers

    (11 People)
  •  唾液IgA産生を促す口腔細菌叢の探索と検証Principal Investigator

    • Principal Investigator
      入江 浩一郎
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Kanagawa Dental College
  •  Epidemiological association between oral health status and secretory IgA levels in saliva

    • Principal Investigator
      友藤 孝明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Asahi University
  •  口腔常在菌叢のdysbiosisに着目した口腔粘膜疾患の病態の解明Principal Investigator

    • Principal Investigator
      入江 浩一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Kanagawa Dental College
  •  Verification of periodontal disease risk through dietary habits targeting advanced glycation end products

    • Principal Investigator
      Azuma Tetsuji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Asahi University
  •  Impact of commensal flora on periodontal immune response to lipopolysaccharidePrincipal Investigator

    • Principal Investigator
      Irie Koichiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Social dentistry
    • Research Institution
      Okayama University
  •  Oral commensal flora accelerates age-related alveolar bone loss in micePrincipal Investigator

    • Principal Investigator
      Koichiro Irie
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Social dentistry
    • Research Institution
      Okayama University
      Aichi Gakuin University
  •  Relationship between occlusal disharmony and Alzheimer's disease

    • Principal Investigator
      EKUNI Daisuke
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Social dentistry
    • Research Institution
      Okayama University
  •  Effects of Hydrogen Sulphide on Osteoclast Differentiation in RatsPrincipal Investigator

    • Principal Investigator
      IRIE Kouichiro
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Social dentistry
    • Research Institution
      Okayama University

All 2023 2022 2018 2017 2016 2015 2013 2011 2010 2009 Other

All Journal Article Presentation

  • [Journal Article] Exploring the Role of IL-17A in Oral Dysbiosis-Associated Periodontitis and Its Correlation with Systemic Inflammatory Disease2023

    • Author(s)
      Irie Koichiro, Azuma Tetsuji, Tomofuji Takaaki, Yamamoto Tatsuo
    • Journal Title

      Dentistry Journal

      Volume: 11 Issue: 8 Pages: 194-194

    • DOI

      10.3390/dj11080194

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10316
  • [Journal Article] Impact of commensal flora on periodontal immune response to lipopolysaccharide2018

    • Author(s)
      Fukuhara D, Irie K, Uchida Y, Kataoka K, Akiyama K, Ekuni D, Tomofuji T, Morita M
    • Journal Title

      Journal of Periodontology

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Journal Article] Age-related changes of CD4+ T cell migration and cytokine expression in germ-free and SPF mice periodontium.2017

    • Author(s)
      Irie K, Tomofuji T, Ekuni D, Fukuhara D, Uchida Y, Kataoka K, Kobayashi S, Kikuchi T, Mitani A, Shimazaki Y, Morita M.
    • Journal Title

      Arch Oral Biol

      Volume: 87 Pages: 72-78

    • DOI

      10.1016/j.archoralbio.2017.12.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11845, KAKENHI-PROJECT-26463149, KAKENHI-PROJECT-16K20694, KAKENHI-PROJECT-17K11999
  • [Journal Article] Site-Specific Neutrophil Migration and CXCL2 Expression in Periodontal Tissue2016

    • Author(s)
      Greer A, Irie K, Hashim A, Leroux BG, Chang AM, Curtis MA, Darveau RP
    • Journal Title

      Journal of Dental Research

      Volume: 印刷中 Issue: 8 Pages: 946-952

    • DOI

      10.1177/0022034516641036

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26893304, KAKENHI-PROJECT-16K20694
  • [Journal Article] Impact of oral commensal bacteria on degradation of periodontal connective tissue in mice2015

    • Author(s)
      Irie K, Tomofuji T, Ekuni D, Morita M, Shimazaki Y, Darveau RP
    • Journal Title

      Journal of Periodontology

      Volume: 86 Issue: 7 Pages: 899-905

    • DOI

      10.1902/jop.2015.150006

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26893304
  • [Journal Article] Impact of Oral Commensal Bacteria on Degradation of Periodontal Connective Tissue in Mice2015

    • Author(s)
      Irie K, Tomofuji T, Ekuni D, Morita M, Shimazaki Y, Darveau RP
    • Journal Title

      Journal of Periodontology

      Volume: - Pages: 1-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26893304
  • [Journal Article] Occlusal disharmony increases amyloid-β in the rat hippocampus.2011

    • Author(s)
      Ekuni D, Tomofuji T, Irie K, Azuma T, Endo Y, Kasuyama K, Morita M.
    • Journal Title

      Neuromolecular Med.

      Volume: 13 Pages: 197-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792512
  • [Journal Article] Occlusal disharmony increases amyloid-β in the rat hippocampus2011

    • Author(s)
      Ekuni D, Tomofuji T, Irie K, Azuma T, Endo Y, Kasuyama K, Morita M
    • Journal Title

      NeuromolecularMed

      Volume: 13巻 Pages: 197-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792512
  • [Journal Article] Occlusal disharmony induces BDNF level in rat submandibular gland.2011

    • Author(s)
      Irie K, Ekuni D, Tomofuji T, Azuma T, Endo Y, Kasuyama K, Morita M
    • Journal Title

      Arch Oral Biol 56

      Pages: 35-40

    • NAID

      120003367828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Journal Article] Effects of periodontitis on aortic insulin resintance in an obese rat model.2010

    • Author(s)
      Ekuni D, Tomofuji T, Irie K, Kasuyama K, Umakosi M, Azuma T, Tamaki N, Sanbe T, Endo Y, Yamamoto T
    • Journal Title

      Lab Invest 90

      Pages: 348-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Journal Article] Imbalanc of oxidative/anti-oxidative status induced by periodontitis is involved in apoptosis of rat submandubular glands.2010

    • Author(s)
      Ekuni D, Endo Y, Irie K, Azuma T, Tamaki N, Tomofuji T, Morita M
    • Journal Title

      Arch Oral Biol 55

      Pages: 170-176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Journal Article] Experimental periodontitis induces gene expression of proinflammatory cytokines in liver and white adipose tissues in obesity.2010

    • Author(s)
      Endo Y, Tomofuji T, Ekuni D, Irie K, Azuma T, Tamaki N, Yamamoto T, Morita M
    • Journal Title

      J Periodontol 81

      Pages: 520-526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Journal Article] Relationship between periodontitis and hepatic abnormalities in youg adults.2010

    • Author(s)
      Furuta M, Ekuni D, Yamamoto T, Irie K, Koyama R, Sanbe T, Yamanaka R, Morita M, Kuroki K, Tobe K.
    • Journal Title

      Acta Odontol Scand 68

      Pages: 27-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Journal Article] A single application of hydrogen sulphide induces a transient osteoclast differentiation with RANKL expression in the rat model2009

    • Author(s)
      Irie K
    • Journal Title

      Archives of oral biology 54

      Pages: 723729-723729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Journal Article] Preventive effects of a cocoa-enriched diet on gingival oxidative stress in experimental periodontitis.2009

    • Author(s)
      Tomofuji T, Ekuni D, Irie K, Azuma T, Endo Y, Tamaki N, Sanbe T, Murakami J, Yamamoto T, Morita M
    • Journal Title

      J Periodontol 80

      Pages: 1799-1808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Journal Article] A single application of hydrogen sulphide induces s transient osteoclast differentiation with RANKL expression in the rat model2009

    • Author(s)
      Irie K, Ekuni D, Yamamoto T, Morita M, Yaegaki K, Ii H, Imai T
    • Journal Title

      Arch Oral Biol 54

      Pages: 723-729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Presentation] 特定の腸内細菌が口腔領域の免疫に与える影響について2023

    • Author(s)
      入江 浩一郎、渕田慎也、東 哲司、友藤孝明、山本龍生
    • Organizer
      第66回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K10316
  • [Presentation] 特定の腸内細菌が口腔領域の免疫に与える影響について2023

    • Author(s)
      入江浩一郎、渕田慎也、東哲司、友藤孝明、山本龍生
    • Organizer
      第66回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K10316
  • [Presentation] 腸内細菌が口腔粘膜免疫に及ぼす影響について2022

    • Author(s)
      入江 浩一郎、持田悠貴、渕田慎也、山本龍生
    • Organizer
      神奈川歯科大学学会 第57回総会
    • Data Source
      KAKENHI-PROJECT-22K10316
  • [Presentation] 3型自然リンパ球で切り拓く予防歯科臨床の未来2022

    • Author(s)
      入江 浩一郎
    • Organizer
      第71回日本口腔衛生学会・総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K10316
  • [Presentation] Commensal flora affects osteoblasts mineralization in mice2017

    • Author(s)
      Uchida Y, Irie K, Hattori T, Fukuhara D, Kataoka K, Ekuni D, Tomofuji T, Kubota S, Morita M
    • Organizer
      Penn Periodontal Conference 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] 常在菌が骨芽細胞に与える影響について2017

    • Author(s)
      内田瑶子、入江浩一郎、福原大樹、片岡広太、江國大輔、友藤孝明、森田学
    • Organizer
      第66回 日本口腔衛生学会
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] LPSを塗布した歯周組織の免疫応答に対する常在菌の影響2017

    • Author(s)
      福原大樹、入江浩一郎、内田瑶子、片岡広太、江國大輔、友藤孝明、森田学
    • Organizer
      第66回 日本口腔衛生学会
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] Impact of commensal bacteria on periodontal immune response against lipopolysaccharide2017

    • Author(s)
      Fukuhara D, Irie K, Uchida Y, Kataoka K, Ekuni D, Tomofuji T, Morita M
    • Organizer
      Penn Periodontal Conference 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] 歯周組織の加齢変化におけるCD4+ T細胞の影響2016

    • Author(s)
      福原大樹、入江浩一郎、内田瑶子、片岡広太、江國大輔、友藤孝明、森田学
    • Organizer
      第65回日本口腔衛生学会・総会
    • Place of Presentation
      東京
    • Year and Date
      2016-05-27
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] The impact of oral commensal flora on alveolar bone metabolism in mice2016

    • Author(s)
      Daiki Fukuhara, Koichiro Irie, Yoko Uchida, Kota Kataoka, Daisuke Ekuni, Takaaki Tomofuji, Manabu Morita
    • Organizer
      Innate Immunity in Host-Pathogen Interactions
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2016-06-26
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] Effect of aging on inflammatory response in periodontal tissue2016

    • Author(s)
      Daiki Fukuhara, Koichiro Irie, Yoko Uchida, Kota Kataoka, Daisuke Ekuni, Takaaki Tomofuji, Manabu Morita
    • Organizer
      Innate Immunity in Host-Pathogen Interactions
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2016-06-26
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] 加齢変化における歯肉のCD4+T細胞への影響の検討2016

    • Author(s)
      福原大樹、入江浩一郎、内田瑶子、片岡広太、友藤孝明、江國大輔、森田 学
    • Organizer
      第65回日本口腔衛生学会・総会
    • Place of Presentation
      東京
    • Year and Date
      2016-05-27
    • Data Source
      KAKENHI-PROJECT-26893304
  • [Presentation] 口腔常在菌が歯槽骨に与える影響について2016

    • Author(s)
      内田瑶子、入江浩一郎、福原大樹、片岡広太、江國大輔、友藤孝明、森田学
    • Organizer
      第65回日本口腔衛生学会・総会
    • Place of Presentation
      東京
    • Year and Date
      2016-05-27
    • Data Source
      KAKENHI-PROJECT-16K20694
  • [Presentation] 口腔常在菌が歯槽骨に与える影響について2016

    • Author(s)
      内田瑤子、入江浩一郎、福原大樹、片岡広太、友藤孝明、江國大輔、森田 学
    • Organizer
      第65回日本口腔衛生学会・総会
    • Place of Presentation
      東京
    • Year and Date
      2016-05-27
    • Data Source
      KAKENHI-PROJECT-26893304
  • [Presentation] Oral commensal flora accelerates age-related alveolar bone loss in mice2015

    • Author(s)
      IRIE K, TOMOFUJI T, EKUNI D, KOBAYASHI S, KIKUCHI T, UCHIDA Y, FUKUHARA D, MITANI A, SHIMAZAKI Y, MORITA M
    • Organizer
      第63回JADR総会・学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26893304
  • [Presentation] 歯周組織の加齢変化に対する口腔常在菌の影響2015

    • Author(s)
      入江浩一郎、友藤孝明、江國大輔、小林周一郎、菊池 毅、内田瑶子、福原大樹、三谷章雄、嶋崎義浩、森田 学
    • Organizer
      第58回秋季日本歯周病学会
    • Place of Presentation
      浜松
    • Year and Date
      2015-09-12
    • Data Source
      KAKENHI-PROJECT-26893304
  • [Presentation] アポリポ蛋白E欠損と咬合異常によるラット海馬および認知障害への影響2013

    • Author(s)
      江國大輔,遠藤康正,友藤孝明,東哲司,入江浩一郎,粕山健太,米田俊樹,森田学
    • Organizer
      第62回日本口腔衛生学会・総会
    • Place of Presentation
      松本市
    • Year and Date
      2013-05-17
    • Data Source
      KAKENHI-PROJECT-23792512
  • [Presentation] 咬合異常はラット海馬におけるβアミロイド量を増加させる2011

    • Author(s)
      江國大輔,友藤孝明,入江浩一郎,東哲司,遠藤康正,粕山健太,森田学
    • Organizer
      口腔衛生学会 近畿・中国・四国地方会総会
    • Place of Presentation
      徳島
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-23792512
  • [Presentation] Combined Effects of Hydrogen Sulphide and Lipopolysaccharide in Rat Periodontium2011

    • Author(s)
      Irie.K
    • Organizer
      89th International Association for Dental Research
    • Place of Presentation
      San Diego
    • Year and Date
      2011-03-19
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Presentation] Combined Effects of Hydrogen Sulphide and Lipopolysaccharide in Rat Periodontium.2011

    • Author(s)
      K.IRIE, D.EKUNI, T.TOMOFUJI, Y.ENDO, K.KASUYAMA, M.MORITA, K.YAEGAKI, H.II, T.IMAI
    • Organizer
      The 89th International Association for Dental Research
    • Place of Presentation
      Barcelona
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Presentation] Combined Effects of Hydrogen Sulphide and Lipopolysaccharide in Rat Periodontium2010

    • Author(s)
      Irie.K
    • Organizer
      9th INTERNATIONAL CONFERENCE OF ASIAN ACADEMY OF PREVENTIVE DENTISTRY
    • Place of Presentation
      Kuala Lumpur
    • Year and Date
      2010-11-10
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Presentation] Combined Effects of Hydrogen Sulphide and Lipopolysaccharide in Rat Periodontium.2010

    • Author(s)
      K.IRIE, D.EKUNI, T.TOMOFUJI, Y.ENDO, K.KASUYAMA, M.MORITA, K.YAEGAKI, H.II, T.IMAI
    • Organizer
      The 9th International Conference of Asian Academy of Preventive Dentistry
    • Place of Presentation
      Kuala Lumpur
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Presentation] Cocoa-enriched diet decreases2009

    • Author(s)
      Irie K, Tomofuji T, Ekuni D, Azuma T, Tamaki N, Endo Y, Sanbe T, Yamamoto TMorita M
    • Organizer
      gingival oxidative stress in rat periodontitis: SFRR
    • Place of Presentation
      Roma, Italy
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Presentation] Hydrogen Sulfide Application Induces a Transient Osteoclast Differentiation with RANKL Expression in the Rat Model2009

    • Author(s)
      Ekuni D, Irie K, Yamamoto T, Morita M, Yaegaki K, Ii H, Imai T
    • Organizer
      The 8th congress of International Society for Breath Odor Research
    • Place of Presentation
      Dortmund
    • Data Source
      KAKENHI-PROJECT-21792149
  • [Presentation] Commensal Bacteria Induces Inflammation in Periodontal Tissue

    • Author(s)
      Koichiro Irie, Takaaki Tomofuji, Daisuke Ekuni, Manabu Morita, Yoshihiro Shimazaki
    • Organizer
      International Association of Dental Research
    • Place of Presentation
      Boston
    • Year and Date
      2015-03-11 – 2015-03-14
    • Data Source
      KAKENHI-PROJECT-26893304
  • [Presentation] 咬合異常はラット海馬におけるβアミロイド量を増加させる

    • Author(s)
      江國大輔,友藤孝明,入江浩一郎,東哲司,遠藤康正,粕山健太,森田学
    • Organizer
      口腔衛生学会 近畿・中国・四国地方会総会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-23792512
  • 1.  TOMOFUJI Takaaki (80335629)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 2.  AZUMA Tetsuji (80432649)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 3.  EKUNI Daisuke (70346443)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 4.  MORITA Manabu (40157904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  ENDO Yasumasa (50580213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 6.  山下 真幸 (80588038)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  岩井 浩明 (20847214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Fukuhara Daiki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 9.  UCHIDA Yoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 10.  三谷 章雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  菊池 毅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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