Murakami Tomohiko 村上智彦

… Alternative Names

MURAKAMI TOMOHIKO 村上智彦

MURAKAMI Tomohiko 村上智彦

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Researcher Number	50510723
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院歯学研究科, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院歯学研究科, 講師 2016 – 2021: 大阪大学, 歯学研究科, 講師 2017: 大阪大学, 大学院歯学研究科, 講師 2015: 大阪大学, 大学院歯学研究科, 講師 2014 – 2015: 大阪大学, 歯学研究科(研究院), 講師 2008 – 2010: University of Miyazaki, 医学部, 助教 2009: 宮崎大, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57020:Oral pathobiological science-related / Pathobiological dentistry/Dental radiology / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Medium-sized Section 57:Oral science and related fields / Functional basic dentistry / Pathological medical chemistry / General medical chemistry Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Functional basic dentistry
Keywords	Principal Investigator 炎症 / 小胞体ストレス / 小胞体 / インフラマソーム / コラーゲン / 骨形成 / 創薬 / 遺伝子モニタリングシステム / 関節破壊 / オルガネラ障害 … More / プロテオーム解析 / 代謝物 / GNB1 / NLRP3 / 骨代謝 / 慢性炎症 / I型コラーゲン / 成長 / 分泌 … More Except Principal Investigator 転写因子 / ゲノム編集 / 関節リウマチ / 細胞内シグナル / 軟骨 / 骨代謝 / 骨 / 軟骨代謝 / 関節軟骨 / 創薬 / 変形性関節症 / 軟骨細胞 / 骨形成 / 唾液腺 / 自己免疫疾患 / セマフォリン / 骨粗鬆症 / 転写プラットフォーム / 内軟骨性骨形成 / 骨系統疾患 / Zfhx4 / 軟骨形成 / 骨格形成 / 炎症 / 炎症性サイトカイン / 骨免疫学 / 再生 / ダイレクトリプログラミング / 関節軟骨生物学 / サイトカイン / Prg4 / Gdf5 / 関節軟骨細胞 / 遺伝子クローニング / 軟骨分化 / ゲノム編集法 Less

Development of novel curative strategies for bone and cartilage diseases based on non-classical Sema4D signalling pathways
- Principal Investigator
  
  西村理行
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
骨・関節破壊モニタリングシステムの開発と臨床応用への基盤構築Principal Investigator
- Principal Investigator
  
  村上智彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Osaka University
炎症性ドライバーIκBζの相反性の理解から挑む自己免疫疾患の発症機序の解明と応用
- Principal Investigator
  
  西村理行
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
慢性炎症と小胞体ストレスの連関機序と病態への関与Principal Investigator
- Principal Investigator
  
  村上智彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Osaka University
Spatio-temporal regulation of skeletal development by the Zfhx family of transcription platform factors.
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Analysis of crosstalk mechanisms of cellular responses in chronic diseasesPrincipal Investigator
- Principal Investigator
  
  Murakami Tomohiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Osaka University
New Opportunity in Bone Immunology to Establish a Drug Discovery Platform for Molecular Targeted Therapeutics for Bone and Cartilage Destructive Diseases.
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Measurement of ER stress without destructionPrincipal Investigator
- Principal Investigator
  
  Murakami Tomohiko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Regulatory mechanism of NLRP3 inflammasome in chronic inflammationPrincipal Investigator
- Principal Investigator
  
  Murakami Tomohiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Establishment of system for predicting inflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  Murakami Tomohiko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka University
Investigation of transcriptional network system of chondrocytes by novel gene-editing cloning technique
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Development of innovative medical technology based on integrated understanding of both protection and destruction of articular cartilage homeostasis.
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Search of the cell type-specific inflammatory responsePrincipal Investigator
- Principal Investigator
  
  Murakami Tomohiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka University
Development of screening system for bone forming reagents by using TALEN genome engineering technique
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
小胞体品質管理機構による骨形成制御の解析Principal Investigator
- Principal Investigator
  
  村上智彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Miyazaki
Analysis of a membrane bound transcription factor OASIS in osteogenesisPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Tomohiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki

[Book] 実験医学小胞体ストレスセンサーによる骨軟骨形成制御2010
- Author(s)
  今泉和則、村上智彦、齋藤敦
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21790323
[Book] 実験医学 28(4)(小胞体ストレスセンサーによる骨軟骨形成制御)2010
- Author(s)
  今泉和則、村上智彦、齋藤敦
- Data Source
  KAKENHI-PROJECT-21790323
[Book] 実験医学 27(4)(骨代謝のダイナミクスにおける小胞体ストレス応答の役割)2009
- Author(s)
  今泉和則、村上智彦
- Data Source
  KAKENHI-PROJECT-21790323
[Journal Article] HOXA10 promotes Gdf5 expression in articular chondrocytes2023
- Author(s)
  Murakami Tomohiko、Ruengsinpinya Lerdluck、Takahata Yoshifumi、Nakaminami Yuri、Hata Kenji、Nishimura Riko
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41598-023-50318-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17438, KAKENHI-PROJECT-22KJ2149, KAKENHI-PROJECT-21K19596, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-23K24513, KAKENHI-PROJECT-23K24519
[Journal Article] Activation and Function of NLRP3 Inflammasome in Bone and Joint-Related Diseases2022
- Author(s)
  Murakami Tomohiko、Nakaminami Yuri、Takahata Yoshifumi、Hata Kenji、Nishimura Riko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 10 Pages: 5365-5365
- DOI
  10.3390/ijms23105365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-23K24513, KAKENHI-PROJECT-23K24519
[Journal Article] Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx22022
- Author(s)
  Yagi Hiroko、Takahata Yoshifumi、Murakami Tomohiko、Nakaminami Yuri、Hagino Hiromasa、Yamamoto Shiori、Murakami Shinya、Hata Kenji、Nishimura Riko
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 40 Issue: 5 Pages: 723-734
- DOI
  10.1007/s00774-022-01345-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-20K20475
[Journal Article] Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes2022
- Author(s)
  Murakami Tomohiko、Takahata Yoshifumi、Hata Kenji、Ebina Kosuke、Hirose Katsutoshi、Ruengsinpinya Lerdluck、Nakaminami Yuri、Etani Yuki、Kobayashi Sachi、Maruyama Takashi、Nakano Hiroyasu、Kaneko Takehito、Toyosawa Satoru、Asahara Hiroshi、Nishimura Riko
- Journal Title
  
  Science Signaling
  
  Volume: 15 Issue: 758
- DOI
  10.1126/scisignal.abl5304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20K09410, KAKENHI-PROJECT-20K09460, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-21K16708, KAKENHI-PROJECT-23K24519
[Journal Article] Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis2022
- Author(s)
  Takahata Yoshifumi, Hagino Hiromasa, Kimura Ayaka, Urushizaki Mitsuki, Yamamoto Shiori, Wakamori Kanta, Murakami Tomohiko, Hata Kenji, Nishimura Riko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 9 Pages: 4672-4672
- DOI
  10.3390/ijms23094672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09827, KAKENHI-PROJECT-21K19596, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-20K20475
[Journal Article] Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx22021
- Author(s)
  Ono Koichiro、Hata Kenji、Nakamura Eriko、Ishihara Shota、Kobayashi Sachi、Nakanishi Masako、Yoshida Michiko、Takahata Yoshifumi、Murakami Tomohiko、Takenoshita Seiichi、Komori Toshihisa、Nishimura Riko、Yoneda Toshiyuki
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1-13
- DOI
  10.1038/s42003-021-01848-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-20K18775, KAKENHI-PROJECT-19K22708, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-20F20407
[Journal Article] Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice2021
- Author(s)
  Nakamura Eriko、Hata Kenji、Takahata Yoshifumi、Kurosaka Hiroshi、Abe Makoto、Abe Takaya、Kihara Miho、Komori Toshihisa、Kobayashi Sachi、Murakami Tomohiko、Inubushi Toshihiro、Yamashiro Takashi、Yamamoto Shiori、Akiyama Haruhiko、Kawaguchi Makoto、Sakata Nobuo、Nishimura Riko
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1258-1258
- DOI
  10.1038/s42003-021-02793-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-19H03836, KAKENHI-PROJECT-19H03858, KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-21K19596, KAKENHI-PROJECT-16H06276
[Journal Article] Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx22021
- Author(s)
  Takahata Yoshifumi、Hagino Hiromasa、Kimura Ayaka、Urushizaki Mitsuki、Kobayashi Sachi、Wakamori Kanta、Fujiwara Chika、Nakamura Eriko、Yu Kayon、Kiyonari Hiroshi、Bando Kana、Murakami Tomohiko、Komori Toshihisa、Hata Kenji、Nishimura Riko
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1199-1199
- DOI
  10.1038/s42003-021-02717-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-19H03836, KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-21K09827, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-21K19596
[Journal Article] Role of interleukin-1 and inflammasomes in oral disease2020
- Author(s)
  Murakami Tomohiko、Takahata Yoshifumi、Hata Kenji、Nishimura Riko
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 62 Issue: 3 Pages: 242-248
- DOI
  10.1016/j.job.2020.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03824, KAKENHI-PROJECT-19K22708
[Journal Article] G protein subunit β1 is an important mediator of the late stage of endochondral ossification.2020
- Author(s)
  Ruengsinpinya L, Murakamia T, Nakamura E, Takahata Y, Hata K, Nakaminamia Y, Okaeb H, Nishimura R.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20475
[Journal Article] Role of interleukin-1 and inflammasomes in oral disease2020
- Author(s)
  Murakami T, Takahata Y, Hata K, Nishimura R
- Journal Title
  
  J Oral Biosci
  
  Volume: 62 Pages: 242-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20475
[Journal Article] G protein subunit β1 is an important mediator of the late stage of endochondral ossification2020
- Author(s)
  Ruengsinpinya Lerdluck、Murakami Tomohiko、Nakamura Eriko、Takahata Yoshifumi、Hata Kenji、Nakaminami Yuri、Okae Hiroaki、Nishimura Riko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 533 Issue: 1 Pages: 90-96
- DOI
  10.1016/j.bbrc.2020.08.119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-19H03824, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19K22708
[Journal Article] Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis.2020
- Author(s)
  Takahata Y, Murakami T, Hata K, Nishimura R．
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: 14 Pages: 165-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20475
[Journal Article] Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis.2020
- Author(s)
  Takahata Y, Murakami T, Hata K, Nishimura R.
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: 13 Issue: 2 Pages: 1-6
- DOI
  10.2174/1874467213666200417122933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-19K22708
[Journal Article] Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases2020
- Author(s)
  Nishimura Riko、Hata Kenji、Takahata Yoshifumi、Murakami Tomohiko、Nakamura Eriko、Ohkawa Maki、Ruengsinpinya Lerdluck
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 4 Pages: 1340-1340
- DOI
  10.3390/ijms21041340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09518, KAKENHI-PROJECT-19K22708, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-19H03824, KAKENHI-PROJECT-19H03836, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-18K19640
[Journal Article] Cutting Edge: G Protein Subunit b 1 Negatively Regulates NLRP3 Inflammasome Activation2019
- Author(s)
  Tomohiko Murakami, Lerdluck Ruengsinpinya, Eriko Nakamura,Yoshifumi Takahata, Kenji Hata, Hiroaki Okae,Shun’ichiro Taniguchi, Masafumi Takahashi and Riko Nishimura
- Journal Title
  
  The Journal of Immunology
  
  Volume: 202 Issue: 7 Pages: 1942-1947
- DOI
  10.4049/jimmunol.1801388
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K19640, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19H03824
[Journal Article] Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS52019
- Author(s)
  Takahata Yoshifumi、Nakamura Eriko、Hata Kenji、Wakabayashi Makoto、Murakami Tomohiko、Wakamori Kanta、Yoshikawa Hiroshi、Matsuda Akio、Fukui Naoshi、Nishimura Riko
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 1 Pages: 619-630
- DOI
  10.1096/fj.201800259r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18K09049
[Journal Article] Transcriptional network systems in cartilage development and disease2018
- Author(s)
  Nishimura Riko、Hata Kenji、Nakamura Eriko、Murakami Tomohiko、Takahata Yoshifumi
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 149 Issue: 4 Pages: 353-363
- DOI
  10.1007/s00418-017-1628-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-16K15788, KAKENHI-PROJECT-16H06393
[Journal Article] 小胞体ストレスセンサーOASISによる骨形成制御2018
- Author(s)
  村上智彦
- Journal Title
  
  THE　BONE
  
  Volume: 32 Pages: 43-47
- Data Source
  KAKENHI-PROJECT-16H06270
[Journal Article] 小胞体ストレスセンサーOASISによる骨形成制御2018
- Author(s)
  村上智彦
- Journal Title
  
  THE　BONE
  
  Volume: 32 Pages: 43-47
- Data Source
  KAKENHI-PROJECT-18K19640
[Journal Article] Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a2018
- Author(s)
  Kida Jumpei、Hata Kenji、Nakamura Eriko、Yagi Hiroko、Takahata Yoshifumi、Murakami Tomohiko、Maeda Yoshinobu、Nishimura Riko
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10375-10375
- DOI
  10.1038/s41598-018-28711-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19640, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270
[Journal Article] Transcriptional network controlling endochondral ossification2017
- Author(s)
  Hata K, Takahata Y, Murakami T, Nishimura R
- Journal Title
  
  J Bone Metab
  
  Volume: 24 Issue: 2 Pages: 75-82
- DOI
  10.11005/jbm.2017.24.2.75
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19749, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-16K15788
[Journal Article] Regulation of Cartilage Development and Diseases by Transcription Factors2017
- Author(s)
  Nishimura Riko、Hata Kenji、Takahata Yoshifumi、Murakami Tomohiko、Nakamura Eriko、Yagi Hiroko
- Journal Title
  
  J Bone Metab
  
  Volume: 24 Issue: 3 Pages: 147-147
- DOI
  10.11005/jbm.2017.24.3.147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-16K15779, KAKENHI-PROJECT-16K15788
[Journal Article] 慢性炎症を基盤にした歯周疾患の病態の理解と治療戦略2016
- Author(s)
  村上智彦
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 26 Pages: 114-120
- Data Source
  KAKENHI-PROJECT-16K15788
[Journal Article] 慢性炎症を基盤にした歯周疾患の病態の理解と治療戦略2016
- Author(s)
  村上智彦
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 26 Pages: 114-120
- Data Source
  KAKENHI-PROJECT-16H06270
[Journal Article] Endoplasmic reticulum stress response mediated by the PERK-eIF2α-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.2011
- Author(s)
  Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener, DR, Imaizumi K.
- Journal Title
  
  Journal of Biological Chemistry 286(6)
  
  Pages: 4809-4818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790323
[Journal Article] Distinct mechanisms are responsible for osteopenia and growth retardation in OASIS-deficient mice.2011
- Author(s)
  Murakami T, Hino S-I, Nishimura R, Yoneda T, Wanaka A, Imaizumi K.
- Journal Title
  
  Bone 48(3)
  
  Pages: 514-523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790323
[Journal Article] Distinct mechanisms are responsible for osteopenia and growth retardation in OASIS-deficient mice2010
- Author(s)
  Murakami T, et al
- Journal Title
  
  Bone
  
  Volume: 48 Pages: 514-523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790323
[Journal Article] Effects of the bisphosphonate risedronate on osteopenia in OASIS-deficient mice.2010
- Author(s)
  Sekiya H, Murakami T, Saito A, Hino S-I, Tsumagari K, Ochiai K, Imaizumi K.
- Journal Title
  
  Journal of Bone and Mineral Metabolism 28(4)
  
  Pages: 384-394
- NAID
  10027208068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790323
[Journal Article] Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.2009
- Author(s)
  Saito A, Hino S-I, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K.
- Journal Title
  
  Nature Cell Biology 11(10)
  
  Pages: 1197-1204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790323
[Journal Article] Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation2009
- Author(s)
  Murakami T, et al
- Journal Title
  
  Nature Cell Biology 11
  
  Pages: 1205-1211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790323
[Journal Article] Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.2009
- Author(s)
  Murakami T, Saito A, Hino S-I, Kondo S, Kanemoto S, Chihara K, Sekiya H, Tsumagari K, Ochiai K, Yoshinaga K, Saitoh M, Nishimura R, Yoneda T, Kou I, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Wanaka A, Imaizumi K.
- Journal Title
  
  Nature Cell Biology 11(10)
  
  Pages: 1205-1211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790323
[Patent] 軟骨・骨・関節疾患の予防または治療用医薬組成物および軟骨・骨・関節疾患の予防または治療用薬剤のスクリーニング方法2021
- Inventor(s)
  村上智彦、西村理行
- Industrial Property Rights Holder
  村上智彦、西村理行
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03824
[Patent] 軟骨・骨・関節疾患の予防または治療用医薬組成物および軟骨・骨・関節疾患の予防または治療用薬剤のスクリーニング方法2020
- Inventor(s)
  村上智彦、西村理行
- Industrial Property Rights Holder
  村上智彦、西村理行
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03824
[Patent] 軟骨・骨・関節疾患の予防または治療用医薬組成物および軟骨・骨・関節疾患の予防または治療用薬剤のスクリーニング方法2020
- Inventor(s)
  西村　理行、村上　智彦
- Industrial Property Rights Holder
  西村　理行、村上　智彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-213230
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 関節破壊と炎症を誘導するセマフォリン4Dの非古典的シグナル経路2024
- Author(s)
  村上智彦
- Organizer
  大阪大学歯学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] セマフォリン4Dは関節軟骨の非古典的シグナル経路を介して関節軟骨破壊と炎症を誘導する2024
- Author(s)
  村上智彦、高畑佳史、波多賢二、蛯名耕介、廣瀬勝俊、中南友里、豊澤悟、浅原弘嗣、西村理行
- Organizer
  日本軟骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] セマフォリン４Dは関節軟骨の非古典的シグナル経路を活性化して関節破壊を誘導する2023
- Author(s)
  村上智彦、高畑佳史、波多賢二、蛯名耕介、廣瀬勝俊、中南友里、豊澤悟、浅原弘嗣、西村理行
- Organizer
  炎症再生医学会
- Data Source
  KAKENHI-PROJECT-23K17438
[Presentation] セマフォリン４Dは関節軟骨の非古典的シグナル経路を活性化して関節破壊を誘導する2023
- Author(s)
  村上智彦、高畑佳、波多賢二、蛯名耕介、廣瀬勝俊、中南友里、豊澤悟、浅原弘嗣、西村理行
- Organizer
  炎症再生医学会
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] Axon guidance molecule Semaphorin 4D induces cartilage destruction by activating non-canonical signaling pathway2023
- Author(s)
  Murakami T, Takahata Y, Hata K, Ebina K, Hirose K, Nakaminami Y, Toyosawa S, Asahara H, Nishimura R
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] Cartilage destruction induced by Semaphorin 4D2023
- Author(s)
  Murakami T
- Organizer
  Bone Biology Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] 関節破壊を誘導するセマフォリン４Dの新シグナル経路―炎症性サイトカインとしての機能―2023
- Author(s)
  村上智彦
- Organizer
  日本骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] 神経軸索ガイダンス因子Semaphorin 4Dは関節軟骨の非古典的シグナル経路を活性化して関節破壊を誘導する2023
- Author(s)
  村上智彦、高畑佳、波多賢二、蛯名耕介、廣瀬勝俊、中南友里、豊澤悟、浅原弘嗣、西村理行
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2022
- Author(s)
  Hata K, Kobayash S, Takahata Y, Murakami T, Nishimura R
- Organizer
  Japan Bone Academy 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 骨軟骨形成におけるGタンパク質サブユニットβ1の機能解析2022
- Author(s)
  村上智彦、高畑佳史、波多賢二、中南友里、西村理行
- Organizer
  第40回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 小胞体ストレスはリポ多糖に対する炎症応答を増強する2022
- Author(s)
  中南友里，村上智彦，高畑佳史，波多賢二，西村理行
- Organizer
  第64回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 小胞体ストレスはリポ多糖に対する炎症応答を増強する2022
- Author(s)
  中南友里，村上智彦，高畑佳史，波多賢二，西村理行
- Organizer
  第64回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] 骨軟骨形成におけるGタンパク質サブユニットβ1の機能解析2022
- Author(s)
  村上智彦、高畑佳史、波多賢二、中南友里、西村理行
- Organizer
  第40回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-23K24519
[Presentation] Challenging of identification of genes in the onset and progression of pathogenesis of osteoarthritis2022
- Author(s)
  Yamamoto S, Hagino H, Murakami T, Hata K, Nishimura R, Takahata Y
- Organizer
  第３５回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析2021
- Author(s)
  小林　紗知, 波多　賢二, 高畑　佳史，村上　智彦，西村　理行
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] Dmrt2 promotes transition of endochondral ossification by linking Sox9 and Runx22021
- Author(s)
  Hata K, Ono K, Nakamura E, Kobayashi S, Takahata Y, Murakami T, Nishimura R
- Organizer
  48th annual meeting of the European Calcified Tissue Society（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] Dmrt2 promotes transition of endochondral ossification by linking Sox9 and Runx22021
- Author(s)
  Hata K, Ono K, Nakamura E, Kobayashi S, Takahata Y, Murakami T, Nishimura R
- Organizer
  48th annual meeting of the European Calcified Tissue Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 軟骨細胞におけるSox9遺伝子の発現制御機構の解明2021
- Author(s)
  小林紗知、波多賢二、高畑佳史、村上智彦、高野洋志、八尾良司、鵜澤成一、西村理行
- Organizer
  第6回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-19H03824
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2021
- Author(s)
  Kobayashi S, Hata K, Takahata Y, Murakami T, Uzawa N, Nishimura R.
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04841
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2021
- Author(s)
  Kobayashi S, Hata K, Takahata Y, Murakami T, Uzawa N, Nishimura R.
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2021
- Author(s)
  Kobayashi S, Hata K, Takahata Y, Murakami T, Uzawa N, Nishimura R.
- Organizer
  ASBMR 2021 Annual Meeting（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] GNB1 (G protein subunit β1) is required for the late stage of endochondral ossification2021
- Author(s)
  Lerdluck Ruengsinpinya, Eriko Nakamura, Yoshifumi Takahata, Kenji Hata, Yuri Nakaminami, Riko Nishimura, Tomohiko Murakami
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03824
[Presentation] Dmrt2 promotes transition of endochondral ossification by linking Sox9 and Runx22021
- Author(s)
  Hata K, Ono K, Nakamura E, Kobayashi S, Takahata Y, Murakami T, Nishimura R
- Organizer
  48th annual meeting of the European Calcified Tissue Society（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04841
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2021
- Author(s)
  S. Kobayashi, K. Hata, Y. Takahata, T. Murakami, N.Uzawa, R. Nishimura
- Organizer
  ASBMR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03824
[Presentation] 軟骨細胞におけるSox9 遺伝子のエンハンサー領域の同定と機能解析2021
- Author(s)
  小林紗知、波多賢二、高畑佳史、村上智彦、西村理行
- Organizer
  第３９回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-19H03824
[Presentation] 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析2021
- Author(s)
  小林　紗知, 波多　賢二, 高畑　佳史，村上　智彦，西村　理行
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04841
[Presentation] 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析2021
- Author(s)
  小林　紗知, 波多　賢二, 高畑　佳史，村上　智彦，西村　理行
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] Gタンパク質サブユニットbeta 1はNLRP3インフラマソームを負に制御する2019
- Author(s)
  村上智彦、Lerdluck Ruengsinpinya、中村恵理子、高畑佳史、波多賢二、西村理行
- Organizer
  第6回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-19H03824
[Presentation] Gタンパク質サブユニットbeta 1はNLRP3インフラマソームを負に制御する2019
- Author(s)
  村上智彦、Lerdluck Ruengsinpinya、中村恵理子、高畑佳史、波多賢二、西村理行
- Organizer
  第6回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-18K19640
[Presentation] ER stress and bone metabolism2019
- Author(s)
  Murakami T
- Organizer
  日本内分泌学会学術総会　日韓シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03824
[Presentation] ER stress and bone metabolism2019
- Author(s)
  Murakami T
- Organizer
  日本内分泌学会学術総会　日韓シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19640
[Presentation] Identification and functional analysis of novel target genes regulated by Runx2.2019
- Author(s)
  Takahata Yoshifumi, Wakamori Kanta, Fujiwara Chica, Nakamura Eriko, Hata Kenji, Murakami Tomohiko, Nishimura Riko
- Organizer
  IFMRS 3rd Herbert Fleisch Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] 転写制御と骨格系疾患の分子機構2018
- Author(s)
  波多　賢二、村上　智彦、高畑　佳史、西村　理行
- Organizer
  第60回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] 転写因子Sox4 はADAMTS4 およびADAMTS5 の発現を誘導して変形性関節症の発症に関与する2018
- Author(s)
  高畑佳史、中村恵理子、波多賢二、若林真、村上智彦、若森幹太、吉川浩史、松田昭生、福井尚志、西村理行
- Organizer
  日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19640
[Presentation] 転写因子Sox4 はADAMTS4 およびADAMTS5 の発現を誘導して変形性関節症の発症に関与する2018
- Author(s)
  高畑佳史、中村恵理子、波多賢二、若林真、村上智彦、若森幹太、吉川浩史、松田昭生、福井尚志、西村理行
- Organizer
  日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06270
[Presentation] Novel aspect of inflammatory molecule in articular cartilage destruction2017
- Author(s)
  Tomohiko Murakami
- Organizer
  Bone Biology Forum
- Invited
- Data Source
  KAKENHI-PROJECT-16K15788
[Presentation] Novel aspect of inflammatory molecule in articular cartilage destruction2017
- Author(s)
  Tomohiko Murakami
- Organizer
  Bone Biology Forum
- Invited
- Data Source
  KAKENHI-PROJECT-16H06270
[Presentation] 骨吸収を誘導する炎症性サイトカインIL-1ｂの産生に関わるインフラマソームの制御機構解析2016
- Author(s)
  村上智彦、高畑佳史、波多賢二、西村理行
- Organizer
  日本骨免疫学会
- Place of Presentation
  ホテルモントレ沖縄(沖縄県国頭郡)
- Data Source
  KAKENHI-PROJECT-16K15788
[Presentation] 骨吸収を誘導する炎症性サイトカインIL-1bの産生に関わるインフラマソームの制御機構解析2016
- Author(s)
  村上智彦、高畑佳史、波多賢二、西村理行
- Organizer
  日本骨免疫学会
- Place of Presentation
  ホテルモントレ沖縄(沖縄県国頭郡)
- Data Source
  KAKENHI-PROJECT-16H06270
[Presentation] ゲノム編集技術を用いた新規プロテインキナーゼの軟骨細胞分化における役割解明2015
- Author(s)
  森　裕美子、萩野　弘将、後藤　満帆、長田　奈幹、高畑　佳史、村上　智彦、波多　賢二、西村　理行
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル東京（東京都新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26670807
[Presentation] 慢性炎症に関連するNLRP3インフラマソームの活性化機構の解析2015
- Author(s)
  村上智彦、高畑佳史、波多賢二、西村理行
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26670818
[Presentation] 小胞体ストレスセンサーOASISファミリーの活性化機構と生体機能調節2010
- Author(s)
  日野真一郎、齋藤敦、村上智彦、津曲健志、落合希実子、今泉和則
- Organizer
  第115回日本解剖学会総会・全国学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] OASIS, an endoplasmic reticulum stress transducer, is involved in bone formation.2010
- Author(s)
  Murakami T, Nishimura R, Yoneda T, Ikegawa S, Imaizumi K.
- Organizer
  Experimental Biology 2010(2010 American Society for Biochemistry and Molecular Biology(ASBMB)Annual Meeting)
- Place of Presentation
  Anaheim, CA, USA.
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体ストレスセンサーOASIS欠損マウスにおける骨形成不全と成長抑制2010
- Author(s)
  村上智彦、西村理行、米田俊之、今泉和則
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体ストレスセンサーOASIS欠損マウスにおける骨形成不全と成長抑制2010
- Author(s)
  村上智彦, 他
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] OASIS, an endoplasmic reticulum stress transducer, is involved in bone formation2010
- Author(s)
  Murakami T, et al
- Organizer
  ASBMB Annual meeting
- Place of Presentation
  Anaheim, USA
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体ストレスセンサーOASISの骨形成における新機能2009
- Author(s)
  村上智彦, 他
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体ストレスセンサーOASISによる骨形成制御2009
- Author(s)
  村上智彦、西村理行、米田俊之、池川志郎、和中明生、今泉和則
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体膜貫通型転写因子OASISと骨形成2009
- Author(s)
  村上智彦、西村理行、米田俊之、古市達哉、和中明生、今泉和則
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体ストレストランスデューサーOASISと骨形成2009
- Author(s)
  村上智彦, 西村理行, 米田俊之, 和中明生, 今泉和則
- Organizer
  第114回日本解剖学会全国学術集会
- Place of Presentation
  岡山
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-20890175
[Presentation] 小胞体ストレスセンサーOASISによる骨格形成制御2009
- Author(s)
  村上智彦
- Organizer
  特定領域研究「タンパク質の社会」2009年度班会議
- Place of Presentation
  伊賀
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体ストレスセンサーOASISの骨形成における新機能2009
- Author(s)
  村上智彦、西村理行、米田俊之、池川志郎、和中明生、今泉和則
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 小胞体膜貫通型転写因子OASISと骨形成2009
- Author(s)
  村上智彦, 他
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21790323
[Presentation] 神経変性疾患発症に関与する炎症の慢性化機構
- Author(s)
  村上智彦、高畑佳史、波多賢二、西村理行
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-26670818

1. Nishimura Riko (60294112)

# of Collaborated Projects: 9 results

# of Collaborated Products: 34 results
2. Hata Kenji (80444496)

# of Collaborated Projects: 9 results

# of Collaborated Products: 35 results
3. TAKAHATA YOSHIFUMI (60635845)

# of Collaborated Projects: 6 results

# of Collaborated Products: 32 results
4. 美島健二 (50275343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 岡江寛明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murakami Tomohiko 村上 智彦

MURAKAMI TOMOHIKO 村上 智彦

MURAKAMI Tomohiko 村上 智彦

Research Projects

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Development of novel curative strategies for bone and cartilage diseases based on non-classical Sema4D signalling pathways

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骨・関節破壊モニタリングシステムの開発と臨床応用への基盤構築Principal Investigator

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炎症性ドライバーIκBζの相反性の理解から挑む自己免疫疾患の発症機序の解明と応用

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慢性炎症と小胞体ストレスの連関機序と病態への関与Principal Investigator

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Spatio-temporal regulation of skeletal development by the Zfhx family of transcription platform factors.

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Analysis of crosstalk mechanisms of cellular responses in chronic diseasesPrincipal Investigator

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New Opportunity in Bone Immunology to Establish a Drug Discovery Platform for Molecular Targeted Therapeutics for Bone and Cartilage Destructive Diseases.

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Measurement of ER stress without destructionPrincipal Investigator

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Regulatory mechanism of NLRP3 inflammasome in chronic inflammationPrincipal Investigator

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Establishment of system for predicting inflammatory diseasesPrincipal Investigator

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Investigation of transcriptional network system of chondrocytes by novel gene-editing cloning technique

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Development of innovative medical technology based on integrated understanding of both protection and destruction of articular cartilage homeostasis.

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Search of the cell type-specific inflammatory responsePrincipal Investigator

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Murakami Tomohiko 村上智彦

MURAKAMI TOMOHIKO 村上智彦

MURAKAMI Tomohiko 村上智彦

[Book] 実験医学小胞体ストレスセンサーによる骨軟骨形成制御2010