KAWAKAMI FUMITAKA 川上文貴

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KAWAKAMI Fumitaka 川上文貴

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Researcher Number	50511896
Other IDs
Affiliation (Current)	2025: 北里大学, 医療衛生学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 北里大学, 医療衛生学部, 准教授 2015 – 2023: 北里大学, 医療衛生学部, 講師 2010 – 2014: 北里大学, 医療衛生学部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 52010:General internal medicine-related / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Basic Section 49040:Parasitology-related / Basic Section 59040:Nutrition science and health science-related / Gastroenterology / Food science
Keywords	Principal Investigator LRRK2 / 高脂肪食 / 炎症性腸疾患 / 消化管粘膜障害 / 消化管 / 十二指腸 / 胃 / 食道 Except Principal Investigator タウ蛋白質リン酸化 / タウ蛋白質 … More / アルツハイマー病 / 模倣分子 / S100様分子 / 幼虫体内移行 / 腸管免疫 / 宿主応答 / RAGE / 蠕虫 / 食事リズム / 脳インスリン抵抗性 / インスリン抵抗性 / 概日時計 / インスリン / アミロイドβ / 血糖値 / 高脂肪食 / アルツハイマー症 / BEMAL-1 / βアミロイド / Tauタンパク質リン酸化 / BMAL-1 / 時計遺伝子 / 運動変化 / 摂食時間変更 / 概日リズム / アミラーゼ / 外分泌 / LC3 / オートファジー / GP2 / 膵臓 / アルツハイマー / タウタンパク質 / βアミロイドタンパク質 / 免疫組織染色 / 脳神経疾患 / 抗酸化物質 / 位相X線画像 / Tau蛋白質リン酸化 / Tau蛋白質 / 位相 X 線画像 / クルクミン / βアミロイド蛋白質 Less

LRRK2変異による糖代謝異常と脳内炎症に着目したパーキンソン病発症機序の解明Principal Investigator
- Principal Investigator
  
  川上文貴
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kitasato University
Regulation mechanism of host immune response by S100-like proteins from parasite helminths
- Principal Investigator
  
  坪川大悟
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Kitasato University
Elucidation of the Mechanism of Abnormal Glucose Metabolism Induced by LRRK2 Mutation and High-Fat Diet: Involvement in the Development of Parkinson's DiseasePrincipal Investigator
- Principal Investigator
  
  Kawakami Fumitaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kitasato University
Analysis of the molecular mechanism of circadian clock and cerebral insulin resistance involving in beta-amyloid deposition
- Principal Investigator
  
  MARUYAMA Hiroko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kitasato University
Investigation of mechanisms of inflammatory bowel disease caused by interaction of high-fat diet and LRRK2, a susceptibility gene of IBDPrincipal Investigator
- Principal Investigator
  
  Kawakami Fumitaka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kitasato University
Clarification of autophagy mechanisms to tracking from exocrine secretory granule membrane
- Principal Investigator
  
  Kawashima Rei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kitasato University
Antioxidant induced decrement of β-amyloid deposits by phase contrast X-ray technique
- Principal Investigator
  
  MARUYAMA Hiroko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kitasato University
Characterization of LRRK2 in enteric nervous systemPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Fumitaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kitasato University

All 2023 2022 2021 2018 2017 2016 2015 2014 2012 2011 Other

All Journal Article Presentation Book

[Book] ヒトの基礎生化学情報(シグナル)伝達と受容体、ホルモン2016
- Author(s)
  川上文貴
- Total Pages
  20
- Publisher
  アイ・ケイ・コーポレーション東京
- Data Source
  KAKENHI-PROJECT-15K19347
[Journal Article] LRRK2: An Emerging New Molecule in the Enteric Neuronal System That Quantitatively Regulates Neuronal Peptides and IgA in the Gut.2017
- Author(s)
  Maekawa T, Kawashima R, Ichikawa T.
- Journal Title
  
  Dig Dis Sci.
  
  Volume: 62 Issue: 4 Pages: 903-912
- DOI
  10.1007/s10620-017-4476-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09323, KAKENHI-PROJECT-17K09392, KAKENHI-PROJECT-15K19347
[Journal Article] Oxidative stress increases megalin expression in the renal proximal tubules during the normoalbuminuric stage of diabetes mellitus.2017
- Author(s)
  Kurosaki Y, Imoto A, Kawakami F, Yokoba M, Takenaka T, Ichikawa T, Katagiri M, Ishii N.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 314 Issue: 3 Pages: F462-F470
- DOI
  10.1152/ajprenal.00108.2017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19347, KAKENHI-PROJECT-17K09392
[Journal Article] Maintaining of the Green Fluorescence Emission of 9-Aminoanthracene for Bioimaging Applications.2017
- Author(s)
  Uchiyama Y, Watanabe R, Kurotaki T, Kuniya S, Kimura S, Sawamura Y, Ohtsuki T, Kikuchi Y, Matsuzawa H, Uchiyama K, Itakura M, Kawakami F, and Maruyama H.
- Journal Title
  
  ACS Omega
  
  Volume: 2 Issue: 7 Pages: 3371-3379
- DOI
  10.1021/acsomega.7b00711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19347
[Journal Article] パーキンソン病原因分子LRRK2によるTauの異常リン酸化機構2016
- Author(s)
  川上文貴，市川尊文
- Journal Title
  
  生化学
  
  Volume: 88 Pages: 248-252
- NAID
  40020843443
- Data Source
  KAKENHI-PROJECT-15K19347
[Journal Article] Influence of H2-receptor antagonists on intestinal mucositis induced by 5-fluorouracil in rats.2016
- Author(s)
  Takafumi Ichikawa, Yoichi Saegusa, Motoko Nakano, Rei Kawashima, Fumitaka Kawakami, Tatsunori Maekawa, Setsuko Sugawara, Kazuhiko Ishihara.
- Journal Title
  
  Cancer Research Frontiers.
  
  Volume: ２ Issue: 1 Pages: 33-42
- DOI
  10.17980/2016.33
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19347
[Journal Article] Elemental diet moderates 5-fluorouracil-induced gastrointestinal mucositis through mucus barrier alteration.2015
- Author(s)
  Kawashima R, Kawakami F, Maekawa T, Yamamoto H, Koizumi W, Ichikawa T.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 76 Issue: 2 Pages: 269-277
- DOI
  10.1007/s00280-015-2790-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19347, KAKENHI-PROJECT-25461026
[Journal Article] Selective enhancement of hypoxic cell killing by tempol-regulated suicide gene expression.2015
- Author(s)
  4.Kagiya G, Ogawa R, Choudhuri R, Cook JA, Hatashita M, Tanaka Y, Koda K, Yamashita K, Kubo M, Kawakami F, Mitchell JB.
- Journal Title
  
  Oncol Rep.
  
  Volume: 34 Issue: 2 Pages: 1065-1073
- DOI
  10.3892/or.2015.4020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19347
[Journal Article] The role of α-synuclein and LRRK2 in Tau Phosphorylation.2015
- Author(s)
  Kawakami F., Ichikawa T.
- Journal Title
  
  Parkinson’s Dis.
  
  Volume: 2015 Pages: 734746-734746
- DOI
  10.1155/2015/734746
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19347
[Journal Article] Suppressive Effect of Dietary Fucoidan on Proinflammatory Immune Response and MMP-1 Expression in UVB-Irradiated Mouse Skin.2015
- Author(s)
  Maruyama H, Tamauchi H, Kawakami F, Yoshinaga K, Nakano T
- Journal Title
  
  Planta Med.
  
  Volume: 81 Issue: 15 Pages: 1370-1374
- DOI
  10.1055/s-0035-1557821
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19347
[Journal Article] Leucine-rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase-3β.2014
- Author(s)
  Kawakami F, Shimada N, Ohta E, Kagiya G, Kawashima R, Maekawa T, Maruyama H, Ichikawa T.
- Journal Title
  
  FEBS J.
  
  Volume: 281 Issue: 1 Pages: 3-13
- DOI
  10.1111/febs.12579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461026, KAKENHI-PROJECT-25860720
[Journal Article] LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth.2012
- Author(s)
  Kawakami F, Yabata T, Ohta E, Maekawa T, Shimada N, Suzuki M, Maruyama H, Ichikawa T, Obata F.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 1 Pages: e30834-e30834
- DOI
  10.1371/journal.pone.0030834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790809
[Journal Article] LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth2012
- Author(s)
  Kawakami F., Yabata T., Ohta E., Maekawa T., Shimada N., Suzuki M., Maruyama H., Ichikawa T. and Obata F
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Data Source
  KAKENHI-PROJECT-23790809
[Journal Article] Bleomycin hydrolase is regulated biphasically in a differentiation- and cytokine-dependent manner: relevance to atopic dermatitis.2011
- Author(s)
  Kamata Y, Yamamoto M, Kawakami F, Tsuboi R, Takeda A, Ishihara K, Hibino T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 8204-8212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790809
[Journal Article] LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations2011
- Author(s)
  Ohta E., Kawakami F., Kubo M., Obata F
- Journal Title
  
  FEBS Lett
  
  Volume: 585 Pages: 2165-2170
- Data Source
  KAKENHI-PROJECT-23790809
[Journal Article] Stimulatory effect of a-Synuclein on the tau-phosphorylation by GSK-3ss2011
- Author(s)
  Kawakami F., Suzuki M., Shimada N., Kagiya G., Ohta E., Tamura K., Maruyama H. and Ichikawa T
- Journal Title
  
  FEBS J
  
  Volume: 278 Pages: 4895-4904
- Data Source
  KAKENHI-PROJECT-23790809
[Journal Article] Stimulatory effect ofα-Synuclein on the tau-phosphorylation by GSK-3ss2011
- Author(s)
  Kawakami F., M. Suzuki, N. Shimada, G. Kagiya, E. Ohta, K. Tamura, H. Maruyama and T. Ichikawa
- Journal Title
  
  FEBS J
  
  Volume: 278 Issue: 24 Pages: 4895-4904
- DOI
  10.1111/j.1742-4658.2011.08389.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591618, KAKENHI-PROJECT-23790809
[Journal Article] LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations.2011
- Author(s)
  Ohta E, Kawakami F, Kubo M, Obata F.
- Journal Title
  
  FEBS lett.
  
  Volume: 585 Pages: 2165-2170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] 消化管寄生線虫感染における終末糖化産物受容体を介した腸管免疫制御機構の解析2023
- Author(s)
  坪川大悟, 佐藤雅, 川上文貴, 川島麗, 市川尊文
- Organizer
  第92回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06996
[Presentation] Receptor for advanced glycation products (RAGE) contributes to negative regulation of type 2 mucosal immunity to the intestinal nematode Nippostrongylus brasiliensis.2022
- Author(s)
  D Tsubokawa, M Satoh, F Kawakami, R Kawashima, T Ichikawa
- Organizer
  15th International Congress of Parasitology (ICOPA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06996
[Presentation] Nippostrongylus brasiliensis感染感受性における終末糖化産物受容体の役割2022
- Author(s)
  坪川大悟, 佐藤雅, 川上文貴, 川島麗, 市川尊文
- Organizer
  第91回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-21K06996
[Presentation] 摂食時間の変更が脳内の炎症に及ぼす影響2021
- Author(s)
  五味未早希、川上文貴、ティティルイン、高橋博之、丸山弘子
- Organizer
  第21回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-18K11108
[Presentation] 消化管粘膜バリア機構に対する高脂肪食摂取の影響に関する解析2018
- Author(s)
  川上文貴, 山下真裕佳, 石川勇太, 寄元映見, 井阪勇輝, 市川尊文
- Organizer
  第88回日本衛生学会
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 高脂肪食摂取マウスにおける腸管粘膜バリア機能の変化2018
- Author(s)
  川上文貴, 山下真裕佳, 石川勇太, 寄元映見, 井阪勇輝, 市川尊文
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] Seaweed extract inhibit phosphorylation of tau in human tau stable expressed HEK293 cells2018
- Author(s)
  Imai M., Kawakami F, Hisanao A, Keiko Y, Takashi K, Hiroko M
- Organizer
  the 46th Myanmar Health Research Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 消化管粘膜バリア機構におけるLRRK2の機能解析2017
- Author(s)
  川上文貴, 井阪勇輝, 水邊慧子, 石川勇太, 山下真裕佳, 川島麗, 前川達則, 市川尊文
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 脂肪組織におけるLRRK2の機能解析2017
- Author(s)
  井阪勇輝, 川上文貴, 石川勇太, 丸山弘子, 川島麗, 前川達則, 市川尊文
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] ワカメ成分による糖代謝促進機構の検討2017
- Author(s)
  今井基貴, 川上文貴, 吉永恵子, 加原卓, 丸山弘子
- Organizer
  第16回日本応用藻類学会
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] Alteration of social behavior and glutamic acid decarboxylase level in the valproic acid-induced autism rat model2017
- Author(s)
  T.T. Win-Shwe, Imai M., N.C. Nway, T.T. Lwin, O. Mar, Maruyama H., Kawakami F., Watanabe H.
- Organizer
  10th world congress Developmental Origins of Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] DSS誘発性腸炎に対する高脂肪食の影響2017
- Author(s)
  川上文貴, 渡辺望, 湯原ひかる, 丸山弘子, 川島麗, 前川達則, 市川尊文
- Organizer
  第137回薬学会年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] ワカメ長期摂取がマウスの肝臓に与える影響の検討2017
- Author(s)
  今井基貴, 川上文貴, 吉永恵子, 加原卓, 丸山弘子
- Organizer
  第71回日本・栄養食糧学会
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 消化管粘膜防御機構に対する高脂肪食摂取の影響2016
- Author(s)
  川上文貴, 渡辺望, 湯原ひかる, 丸山弘子, 川島麗, 前川達則, 市川尊文
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] ストレス性消化管運動障害に関わる新規分子の解析2016
- Author(s)
  津島博道、前川達則、川上文貴、川島麗、市川尊文
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 放射線照射モデルを用いたH2受容体拮抗薬の効果2016
- Author(s)
  川島麗, 香渡優, 川上文貴, 前川達則, 菅原節子, 石原和彦, 五艘行信, 市川尊文
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] ワカメ摂取が脂肪の産生に及ぼす影響について2016
- Author(s)
  渡辺希、今井基貴、千葉むつみ、川上文貴、吉永恵子、加原卓、丸山弘子
- Organizer
  第15回日本応用藻類学会
- Place of Presentation
  東京
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] ストレス性消化管運動障害に関わる新規分子の解析2016
- Author(s)
  津島博道, 前川達則, 川上文貴, 川島麗, 市川尊文
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] ワカメは高脂肪食摂取マウスの耐糖能異常を抑制する2016
- Author(s)
  今井基貴, 川上文貴, 千葉むつみ, 渡辺希, 吉永恵子, 加原卓, 丸山弘子
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] ワカメが高脂肪食摂取マウスの肝臓における脂肪代謝に及ぼす影響2016
- Author(s)
  今井基貴、川上文貴、川島良輔、牧喜子、渡辺希、吉永恵子、加原卓、丸山弘子
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 消化管運動におけるLRRK2の機能解析2015
- Author(s)
  津島博道、前川達則、山下博徳、雲井利亮、川上文貴、川島麗、市川尊文
- Organizer
  第88回日本生化学会
- Place of Presentation
  兵庫県神戸市（神戸国際会議場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] わかめ摂取が糖代謝に及ぼす影響について2015
- Author(s)
  千葉むつみ、今井基貴、川上文貴、吉永恵子、加原卓、丸山弘子
- Organizer
  第14回日本応用藻類学会
- Place of Presentation
  東京都品川区（東京海洋大学）
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 真コンブ摂取による高脂肪摂食マウスの耐糖能に及ぼす影響2015
- Author(s)
  丸山弘子、渡邉栄美子、呉谷奈央子、圓子侑希、鈴木麻耶、川上文貴
- Organizer
  第88回日本生化学会
- Place of Presentation
  兵庫県神戸市（神戸国際会議場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] パーキンソン病原因分子LRRK2とp53の相互作用とリン酸化2015
- Author(s)
  川上文貴、川島麗、前川達則、市川尊文
- Organizer
  第88回日本生化学会
- Place of Presentation
  兵庫県神戸市（神戸国際会議場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] 神経細胞LRRK2を介する腸管上皮細胞調節機構の解析2015
- Author(s)
  山下博徳、前川達則、津島博道、雲井利亮、川上文貴、川島麗、市川尊文
- Organizer
  第88回日本生化学会
- Place of Presentation
  兵庫県神戸市（神戸国際会議場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] パーキンソン病原因分子LRRK2とp53の相互作用とリン酸化2015
- Author(s)
  川上文貴、川島麗、前川達則
- Organizer
  MBM2015
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25461026
[Presentation] ワカメによる高脂肪摂取マウスの耐糖能異常に対する改善効果2015
- Author(s)
  今井基貴、千葉むつみ、川上文貴、吉永恵子、加原卓、丸山弘子
- Organizer
  第36回　日本肥満学会
- Place of Presentation
  愛知県名古屋市（名古屋国際会議場）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K19347
[Presentation] GSK-3βによるTauのリン酸化に対するα-Synucleinの促進効果2012
- Author(s)
  川上　文貴，山田　雄基，川島　麗，市川　尊文
- Organizer
  第132年会日本薬学会
- Place of Presentation
  北海道大学札幌キャンパス（北海道）
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] 神経軸索伸長制御におけるLRRK2によるタウのリン酸化の生理的役割2012
- Author(s)
  川上文貴
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] Biochemical characterization of α-synuclein as a stimulator for the gsk-3β-mediated phosphorylation of tau protein.2012
- Author(s)
  Fumitaka Kawakami
- Organizer
  22nd IUBMB37th FEBS congress
- Place of Presentation
  Sevilla, Spain
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] Takafumi Ichikawa Biochemical characterization of a-synuclein as a stimulator for the gsk-3ss-mediated phosphorylation of tau protein2012
- Author(s)
  Fumitaka Kawakami, Minori Suzuki, Yuki Yamada, Rei Kawashima
- Organizer
  37th FEBS congress
- Place of Presentation
  Sevilla
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] 神経軸索伸長制御におけるLRRK2 によるタウのリン酸化の生理的役割2012
- Author(s)
  川上文貴、山田雄基、川島麗、石原和彦、市川尊文
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] GSK-3ss による Tau のリン酸化に対するa-Synuclein の促進効果2012
- Author(s)
  川上文貴,山田雄基,川島麗,市川尊文
- Organizer
  第132 年会日本薬学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] クルクミンによるβアミロイド蛋白質産生抑制効果の基礎的検討2012
- Author(s)
  大泉孝仁、丸山弘子、國井琢矢、白井亮多、秋田久直、川上文貴、大部誠、武田徹
- Organizer
  第66回日本栄養・食糧学会講演要旨集
- Place of Presentation
  仙台
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22580145
[Presentation] クルクミンによるβアミロイド蛋白質産生抑制効果の基礎的検討2012
- Author(s)
  大泉孝仁、丸山弘子、國井琢矢、白井亮多、秋田久直、川上文貴、大部誠、武田徹
- Organizer
  第66回日本栄養・食糧学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22580145
[Presentation] アルツハイマーモデルマウスにおけるクルクミンの発症抑制効果2012
- Author(s)
  大泉孝仁、丸山弘子、國井琢矢、白井亮多、秋田久直、川上文貴、大部誠、武田徹
- Organizer
  第25回北里大学バイオサイエンスフォーラム
- Place of Presentation
  東京
- Year and Date
  2012-08-02
- Data Source
  KAKENHI-PROJECT-22580145
[Presentation] LRRK2 による p53 のリン酸化とその生理的役割に関する解析2012
- Author(s)
  山田雄基、川上文貴, 川島麗、市川尊文
- Organizer
  第85回日本生化学会
- Place of Presentation
  神戸市, 福岡市
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] GSK-3betaによるtauのリン酸化に対するHsp70の抑制作用2011
- Author(s)
  川上文貴、鈴木美乃里、山田雄基、川島麗、市川尊文
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] GSK- による tau のリン酸化に対する Hsp70 の抑制作用2011
- Author(s)
  川上文貴、鈴木美乃里、山田雄基、川島麗、市川尊文
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23790809
[Presentation] 5-Fluorouracil起因性消化管粘膜傷害において成分栄養剤がムチン分泌機能に与える影響
- Author(s)
  雲井利亮、川島麗、曽根暦美、杉元くるみ、星菜奈海、坂井唯人、菅原節子、前川達則、川上文貴、市川尊文
- Organizer
  第26回北里大学バイオサイエンスフォーラム
- Place of Presentation
  北里大学相模原キャンパス（神奈川県相模原市）
- Year and Date
  2014-08-21 – 2014-08-22
- Data Source
  KAKENHI-PROJECT-25461026
[Presentation] 5-Fluorouracil起因性消化管粘膜傷害に対する成分栄養剤の効果
- Author(s)
  川島麗、雲井利亮、菅原節子、前川達則、川上文貴、石原和彦、市川尊文
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25461026
[Presentation] LRRK2によるGSK-3βの活性化を介したタウのリン酸化調節
- Author(s)
  川上文貴、川島麗、前川達則、嶋山ひとみ、石原和彦、市川尊文
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-25461026

1. Kawashima Rei (70392389)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. MARUYAMA Hiroko (50129269)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. ICHIKAWA Takafumi (30245378)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. 小寺義男 (60265733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKEDA Tohoru (10197311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 佐々木徹 (30158927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 坪川大悟 (30714901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 佐藤雅 (40611843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 緒形雅則 (20194425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 今井基貴 (50908457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAGIYA Go

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAKAMI FUMITAKA 川上 文貴

KAWAKAMI Fumitaka 川上 文貴

Research Projects

Research Products

Co-Researchers

LRRK2変異による糖代謝異常と脳内炎症に着目したパーキンソン病発症機序の解明Principal Investigator

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Regulation mechanism of host immune response by S100-like proteins from parasite helminths

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Elucidation of the Mechanism of Abnormal Glucose Metabolism Induced by LRRK2 Mutation and High-Fat Diet: Involvement in the Development of Parkinson's DiseasePrincipal Investigator

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Analysis of the molecular mechanism of circadian clock and cerebral insulin resistance involving in beta-amyloid deposition

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Investigation of mechanisms of inflammatory bowel disease caused by interaction of high-fat diet and LRRK2, a susceptibility gene of IBDPrincipal Investigator

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Clarification of autophagy mechanisms to tracking from exocrine secretory granule membrane

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Antioxidant induced decrement of β-amyloid deposits by phase contrast X-ray technique

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Characterization of LRRK2 in enteric nervous systemPrincipal Investigator

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[Book] ヒトの基礎生化学 情報(シグナル)伝達と受容体、ホルモン2016

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[Journal Article] LRRK2: An Emerging New Molecule in the Enteric Neuronal System That Quantitatively Regulates Neuronal Peptides and IgA in the Gut.2017

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[Journal Article] Oxidative stress increases megalin expression in the renal proximal tubules during the normoalbuminuric stage of diabetes mellitus.2017

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[Journal Article] Maintaining of the Green Fluorescence Emission of 9-Aminoanthracene for Bioimaging Applications.2017

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[Journal Article] パーキンソン病原因分子LRRK2によるTauの異常リン酸化機構2016

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NAID

Data Source

[Journal Article] Influence of H2-receptor antagonists on intestinal mucositis induced by 5-fluorouracil in rats.2016

Author(s)

KAWAKAMI FUMITAKA 川上文貴

KAWAKAMI Fumitaka 川上文貴

[Book] ヒトの基礎生化学情報(シグナル)伝達と受容体、ホルモン2016